#mip 99
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mewguca · 1 month ago
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I had a dream that it was their birthday yesterday. happy late birthday NA (I don't think they have a canon birthday I just wanted to draw them looking stupid. theyve never celebrated a birth or activation date before I'd imagine)
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fum1r · 3 months ago
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Meep
Someday I will learn to draw hands
gift for @mewguca
Initially wanted to make it look like an icon, but I had issues with colouring and.. yeah
Black n white version undercut
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Intro Post
still on indefinite hiatus whoops.
This blog focuses on my Rain World OCs involved in the "Mobile Iterator Project" AU. ^_^
The “Mobile Iterator Project” (MIP) is a project created and directed by an Ancient named "No Cost Too Great" (NCTG) with the stated goal of supporting standard iterators in their productivity, maintenance, and longevity, so that they can operate at maximum efficiency, even after the inevitable mass ascension. ‘MIP Units’—iterators under the project—are created puppet-first in the "MIP Development Center" and later assigned to Local Groups, where their structures are built to support the Iterators around them. Uniquely, their personalities are heavily based around singular, specific Architects (Ancients) who donate their memories and qualia. The exception to this is TWR. In total, there are 99 MIP Units, with IDs ranging from 01 to 99.
(This AU strays pretty far from the themes and canon of both Vanilla Rain World and Downpour, so please keep that in mind!)
⚠️Importantly, here are some warnings for sensitive content that may appear in the posts:
depictions of trauma and mental illness
heavy themes of manipulation (including memory manipulation)
depictions of emotional abuse
dehumanization
depictions of dissociation
identity struggles
medical malpractice/abuse, experimentation
child endangerment
generally dark themes
violence, physical abuse
infrequent body horror
When sensitive content comes up, I will leave a warning before the cut and tag as "sensitive content"!
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Characters:
Starlight Symphony (SLS) she/her, [bio]
Frosted Briar (FB) she/they, [bio]
Glimmering Seafoam In Sunlight (GSIS) she/her, [bio]
Thorns Without Roses (TWR) she/they, [bio]
Perpetual Umbra (PU) they/them, [bio]
Legacy Of Famine (LOF) she/any, [bio]
*These are not all of the characters, just the main 6 that are open to receiving asks.
How it works:
Please specify who you are asking the question to, for example: (to SLS), (to SLS and FB), (to any), (to all), (to admin)
If you don’t specify, I’ll just pick myself. Though, sometimes, I might have another character answer too, if I think it might be interesting.
For admin asks, my friend’s overseer might want to add stuff too, so don’t be surprised if she shows up. For simplicity's sake, assume all admin asks are addressed to potentially both of us.
Additionally, I might add commentary sometimes, which I’ll tag with #admin commentary. My friend might do that too sometimes, so #overseer commentary for her.
I’ll do my best to answer your asks, with varying art quality, though I won’t answer all of them. Jade might answer some of them too, primarily the ones regarding, FB, as she knows them way better than I do.
We will sign off at the end of each post, denoting who handled the “broadcast” (ask.)
[Broadcast handled by admin], [Broadcast handled by overseer], [Broadcast handled by admin and overseer]
There is a light roleplaying/interactive element: The in-universe framing device for the questions is broadcasts being sent to the iterators, hence the ask button’s title. There may also be some occasional meta shenanigans.
I will be answering some questions from curiouscat rather than tumblr, and I will crosspost to twitter, too. This is probably too much work, but whatever. The askblog will be the main source of my attention, though, so posts will come here first.
Boundaries/Rules:
Please don’t ask questions related to your own OCs, because I don’t know them.
Please try to break up multiple questions into separate asks.
Nothing NSFW or suggestive.
No “magic” asks (like turning the characters into different things)
You can send items if you want, though
Please keep in mind that Frosted Briar is, for all intents and purposes, basically a child.
Rules may change as things go along and we figure stuff out!
Non-Ask Posts:
Occasionally, I may post content related to backstories and worldbuilding and stuff unrelated to asks. This will be tagged with #mip logs.
Tags:
#silly: for silly stuff
#angst: for angsty stuff
#dubiously canon: usually used in tandem with silly, but for anything that has questionable characterization
#sensitive content: content that may be triggering or upsetting
#mip worldbuilding: asks/posts related to worldbuilding
#mip lore: asks/posts related to lore!
#mip ask: in-universe asks for the ocs.
#admin ask: asks directed towards the admin/overseers
#guest appearance: asks where characters outside of the main 6 appear.
#mip logs: non-ask posts that build upon the lore/worldbuilding
#ooc: update posts, rule posts, etc.
#meta: hehe
#admin commentary: commentary from the admin (luna)
#overseer commentary: commentary from the overseer (jade or clover)
#overseer assistance: for when the overseers help with the process
#fanart: reblogs of fanart!! :D
#admin art: reblogs of luna’s, jade's or clover's art of the characters
#luna art, #jade art, #clover art: self-explanatory
#old: from the sls ask blog, consider it non-canon
#mobile iterator project, #rw mip au: self-explanatory
post is tagged with most of these
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Main Admin: Luna, @mewguca
Overseer: Jade, @fauxbia
Overseer: Clover, @cloverlady
Thank you for reading!
For additional information on my OC usage permissions, please read my carrd
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entheundead · 3 months ago
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Conlang update!1!1! Did my first totally 100 words that equal to a hundred (source: 100==100) (secondary source 103===100) update: 102==100 trust
1. Sash - I/me
2. Ter - You (singular)
3. Pem - He/she/it
4. Ley - We/us
5. Shus - You (plural)
6. Mip - They/them
7. Rishlem - Person
8. Pip - Animal
9. Yey - Rock
10. Tis - To see
11. Map - To sit
12. Liymet - To give
13. Rat - Big
14. Sit - Small
15. Lim - Many
16. Rey - To go
17. Rut - To finish
18. Shil - To be
19. Ruy - To cause
20. Tat - Tree
21. Sam - Place
22. Tatsam - Forest
23. Tarrat - Fire
24. Tarratsam - Firepit
25. Mitris - Grass
26. Mitrissam - Field
27. Tulyit - Home
28. Tulyitsam - House
29. Puysem - To hunt
30. Tut - Fish
31. Tutpuysem - Fishing
32. Puysemrishlem - Hunter
33. Tutpuysemrishlem - Fisherman
34. Pir - Zero
35. Tim - One
36. Yul - Two
37. Rash - Three
38. Lay - Four
39. Mes - Five
40. Sep - Six
41. Shat - Seven
42. Tur - Eight
43. Mesh - Nine
44. Tapsat - To talk
45. Satrer - Fast
46. Latses - Slow
47. Pashsal - White/bright/day
48. Lasshap - Black/dark/night
49. Mut - Red/blood
50. Sarray - Yellow/sun
51. Tashrus - Green/blue/teal
52. Yamtep - Brown
53. Yat - Warm/hot
54. Shal - Cold
55. Misput - Sky
56. Shiymir - Thing/stuff
57. Lit - Food
58. Lurret - To drink/eat
59. Shammur - Spider
60. Tisris - Snow/to snow
61. Yulshul - To wear
62. Tuptup - To use
63. Yushlem - To make
64. Tit - To love
65. Rum - Yes
66. Mur - No
67. Piy - And
68. Tapsip - To grab
69. Parpar - Bird
70. Tissap - To kill
71. Sharlut - Flower
72. Mis - Very
73. Larshuy - Pretty/beautiful
74. Tapsattashrus - River
75. Tuttulyit - Lake
76. Tatlit - Fruit/berries
77. Piplit - Meat
78. Turlur - Time
79. Yip - Dirt
80. Shuysiy - Wind
81. Pup - To grow
82. Sharlutpup - To bloom
83. Tashrustapsat - To swim
84. Sharlutpupturlur - Spring
85. Shammurturlur - Summer
86. Tapsitshiymir - Hand/arm
87. Patshashshiymir - Foot/leg
88. Rishlemsam - Town
89. Patlis - Clothes
90. Ril - Dek
91. Muy - El
92. Pap - Do
93. Patlisyushlem - To sew
94. Patlisyushlemrishem - Seamstress
95. Litrishlem - Chef
96. Tatshiymir - Wood
97. Mam - Parent
98. Yum - Sibling
99. Sillum - Old
100. Sirlet - Young
101 Lil - Child
102. Tupshim - Bone
I'll also include my thought process for these later.
Sure hope there isn't a random n in the words which has happened with rishlem becoming rishlan and me needing to erase and rewrite the word in my physical notebook several times.
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mip-dev-center · 22 days ago
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RAR Containment Post (1)
i don't know how to explain RAR. they're... an AU character, I guess? like... Director's mipsona. They have a lot of spoilers surrounding them, though.
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I love you thorns without roses. also i forgot to mention it is their. Unwilling mipsona
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the idea was that they had an arm welded on, and eventually it would break off as their structure received more damage. I don't really want this direction anymore, I think. They don't need to be welded to their connector arm to be trapped and contained, and I'd like them to get carried around a bit. the idea that they mellow out and become a better person is going to stick, though.
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design brainstorming. the wings reminded me too much of someone else's concept and the vulture inspiration isn't quite what I wanted so I changed them later. The concept behind their design was to create something like an inversion of NCTG. their design is quite ornate, but it makes them look like some kind of trinket / display piece rather than an intimidating and important member of society. A pointed commentary on MIP Unit design trends.
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This was mainly spurred on by Thorns. Later, I refine the idea somewhat to include 99... I need to work on that. Anyways, the insurrection was initially carried out without input from PU and SLS. They helped after things were already set in motion, but... Unlike TWR, they successfully repressed their desires to revolt, and a change in the status quo is scary for them. It's kind of complicated; they have very negative feelings towards NCTG, but they can't imagine life without following their commands. They're very conditioned.
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sylvietg · 15 days ago
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I'd also like to add for Horizon, specifically, they could use procedural textures for 99% of the robots and facilities and it would run leaner and look better,even on PS4/5 - get a good metal shader, a couple good flow shaders, and your base could be a single 7f7f7f pixel and the robot would look every bit as good. Likely don't even need displacement or other fancy layers - but instead they're sending 4k by 4k textures with dozens of mip maps that are spectacularly large given the percentage of pixels that ever factor into the actual display, even at 4k.
One thing there is NVidia, specifically, replaces shaders with less detailed ones, simplifies textures, etc. - this is what game ready means - and then on top of that, is going to use AI to synthesize lower quality frames to keep up rates. But I think the big issue is that they've been covering hard for optimization in the drivers - which means if I am a large company, rather than pay a programmer to optimize a shader, I can just use unoptimized garbage, and NVidia will find it and fix it
And tools like Unreal Engine and Unity often don't help - you go into the asset store and pull down a random texture, and it likely is not optimized. You feed them a PNG, and they likely don't optimize even that without third party add ones.
Another thing driving this is in engine cut scenes. Civ 7, as an example, has a massive, multiple minute video that everyone is going to skip after the first time. I've not checked files on it, but Civ 5 and 6 put OVER 20 COPIES of the video file, versus just using separate audio tracks for each supported language. And installs all of those files all of the time, with them also not using a particularly good codec.
If you're releasing in multiple languages, package them as free DLC, if you're not packaging different regional packages. This lets people not install gigs of audio they're never going to hear.
this is a controversial opinion and I’m not a gamer but I don’t need my graphics to be that good. I don’t need to see every individual feather on a bird. my poor computer doesn’t deserve to carry that weight either.
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merkabici · 1 year ago
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Características de los cascos de carretera
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Las Características de los cascos de carretera se basan en pruebas realizadas sobre el comportamiento de la resistencia de los materiales usados para su fabricación ante un eventual impacto. Normalmente hoy en día están fabricados con policarbonato; material muy liviano y altamente resistente. Están  elaborados en diferentes diseños con muy variados colores altamente atractivos. Las almohadillas internas generalmente son fabricadas con espuma de poli estireno expandido de alta densidad para lograr la mayor protección posible. Las correíllas de ajuste son cintas de poliéster, siendo las hebillas fabricadas con poliamida de alta tenacidad y también con polioximetileno de mucha resistencia. Los modelos de cascos de carretera más buscados por ciclistas En el mercado ciclístico se consiguen los modelos de cascos de carretera más buscados por ciclistas. Los cuales se basan en variedad de diseños y colores por lo que nos vamos a permitir reseñar algunos de los más solicitados. Casco de carretera Moon Podemos nombrar por ejemplo el casco ciclismo Moon que es un casco atractivo y funcional. Es un casco que cumple con las expectativas de ciclistas exigentes ya que es muy cómodo. Posee buenas almohadillas y una cinta ajustable bastante resistente, se fabrica en variados colores y sirve para ciclismo de carretera como de montaña. Casco de carretera Catlike Mixino Es un casco fabricado con policarbonato expandido de alta densidad en variados colores. Viene con protecciones interiores elaboradas con espuma de poliestireno igualmente de alta densidad capaces de absorber un impacto muy fuerte que se distribuya hacia el casco propiamente dicho sin permitir daños al cerebro. El precio promocional actualmente del casco Catlike Mixino es de 174.95 euros y es ampliamente recomendado como el mejor casco por los hermanos Antón, Ion y Gorka Izaguirre todos ellos pertenecientes al Movistar Team. Por eso es bueno tener en cuenta cuáles son las Características de los cascos de carretera para así escoger el mejor. Casco Catlike Whisper Este es un casco que presenta tecnologías novedosas como es el diseño LNP que se caracteriza por ser un diseño trasero que proporciona mayor protección en la zona occipital. También incorpora la tecnología FES que consiste en que las tomas de aire afecten a más de un nervio por lo que se logra que la energía del impacto se distribuya equilibradamente y no afecte al cerebro. Tiene incorporado el sistema Dual Flow que permite la fluidez del aire gracias a las 39 tomas de aire que tiene en la parte frontal. Estas permiten un flujo de aire constante entre las almohadillas y la cabeza. Por lo que siempre van a sentir frescura los ciclistas ya que el aire sale por unas mini toberas colocadas en la parte posterior del casco. Con respecto a los precios de los cascos Catlike. Se consiguen variadas ofertas en las tiendas especializadas y particularmente Amazon ofrece el casco Catlike Whisper SV en 99 euros y por los momentos lo oferta en 52.18 euros. Igualmente el Catlike Vaccum lo ofrecen en 68.96 euros y el casco Catlike Whisper Plus en colores blanco y rojo lo están vendiendo en oferta especial de 39.99 euros. De esta manera al saber las características de los cascos de carretera podrás escoger el que mejor te parezca conveniente. Casco de carretera POC Octal AVIP MIPS Los cascos de carretera marca POC Octal AVIP MIPS son muy reconocidos en el mundo del ciclista. Más que todo por el diseño de los mismos, que son fácilmente reconocibles y en la construcción de estos afamados cascos se utiliza tecnología de última generación. Más que todo en lo que respecta a seguridad en ciclismo. Este casco no es la excepción bajo ningún concepto y por lo tanto se privilegia los puntos clave que han colocado a esta famosa marca en el tope de la popularidad entre los ciclistas más pudientes económicamente hablando, y como siempre se toman en cuenta primero que todo la aerodinámica, la ventilación y el poco peso de los mismos. Además presenta la novedad de integrar el sistema MPS que traducido al castellano significa protección frente a los impactos multi direccionales. Lo que proporciona una mayor protección contra las fuerzas de rotación, que es la mayor fuerza que se produce durante los impactos. Además proporciona mayor protección a las sienes y a la parte occipital de la cabeza. Sus precios en algunas tiendas se encuentran en 345 euros pero en Amazon se encuentran en oferta por pocos días en 180 euros y los otros modelos están rebajados a 149.90 euros. Lo que significa una buena ganga que invita a comprar aprovechando los excelentes precios promocionales que se ofertan en estos momentos. Casco de carretera Kask Mojito Estos cascos de carretera diseñados por la marca italiana Kask y denominados Mojito cuentan de avances tecnológicos con un excelente diseño al mejor estilo italiano. Que marcará tendencia cuando los ciclistas salgan a pedalear por carreteras, calles y avenidas de las diferentes ciudades de Italia y del mundo. Tiene muy buena ventilación además de que cuenta con avanzados sistemas de protección. Se consiguen en diferentes colores todos ellos muy a la moda vanguardista. Hay variedad de precios en las tiendas especializadas pero sus valores rondan entre los 99 euros y los 120 euros, por lo que la adquisición de uno de ellos brindará al rider la mejor protección y comodidad. 5 ventajas de usar casco de carretera mientras conduces bicicleta Conducir bicicleta es muy recomendable para la salud, pero es bueno conocer 5 ventajas de usar casco de carretera mientras conduces bicicleta. Porque de esta forma te estas comportando como un buen ciudadano que cumple con las leyes regulatorias que regulan el tránsito de este tipo de vehículos. Y que solo buscan proteger al ciclista quien es el más vulnerable en caso de sufrir un accidente. Por esta razón te queremos indicar cuales son las ventajas que implican el uso de casco protector para tu cabeza. Porque como bien sabes esta parte de nuestro cuerpo es muy susceptible a la fuerza de un impacto donde de la manera más simple lo menos que te puede ocurrir es una fractura de cráneo con las concebidas consecuencias fatales. Lo primero que hace un ciclista responsable antes de salir es ajustarse su casco para evitar golpes en la cabeza, con posibles graves lesiones cerebrales. Ya que el sabe muy bien cuáles son las características de los cascos de carretera. Cuando el ciclista porta el casco conduce su bici con seguridad y mucha confianza al pedalear. Usando el casco por lógica te sientes más protegido y en caso de un accidente el golpe en la cabeza es absorbido por el casco y su goma interna que absorbe el golpe minimizando el impacto. Ya teniendo en cuenta cuáles son las características de los cascos de carretera. Es bueno acotar que los cascos hoy en día son muy ligeros y son fabricados con policarbonato. Un material sumamente ligero, pero resistente a los golpes. La mayoría de los cascos para ciclistas cumplen con estándares internacionales de seguridad. Read the full article
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bettervewor · 2 years ago
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Qualcomm atheros qca9377 wireless network adapter aoss
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#QUALCOMM ATHEROS QCA9377 WIRELESS NETWORK ADAPTER AOSS DRIVER#
#QUALCOMM ATHEROS QCA9377 WIRELESS NETWORK ADAPTER AOSS PORTABLE#
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#QUALCOMM ATHEROS QCA9377 WIRELESS NETWORK ADAPTER AOSS DRIVER#
However, all the methods are reliable, also easy enough to execute. Aaro Koskinen PATCH MIPS: OCTEON: caviumocteondefconfig: re-enable OCTEON USB driver (Sat 17:08:30 EST) Aaron Lu. Qualcomm Atheros reference design miniPCIe Wi-Fi modules with best parametrs, High Power and compatibility!Ĭheck Wodaplug dual SIM 4G / 5G LTE routers with ROOTer firmware! Qualcomm Atheros AR956x Wireless Network Adapter Driver Download: Done Thus, with the help of the above-mentioned strategies, you can find the most up-to-date and genuine network adapter drivers. For support write email to support.įor News and Promo - pleasae visit and follow as on our 524WiFi Facebook! Please, if you are distributor / dealer or ISP, first create account and mail to us for business login with discount. 524wifi is part of Google Customers Reviews program to assure customers satisfaction - Google Approved. Quectel leads market in LTE 5G 4G modules & IoT technologies. Wodaplug offers reliable solution for Ethernet Data over Coax (EOC), G EPON and 4G 5G LTE routers & backup units. With more than 18 years of experience in the Networking Industry, our partners are Wodaplug & Quectel & Compex & Wallys communications. 11ac wireless adapter, the IGX-PACAF1-9880a1 operates in 2.
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qualcomm QCA9331 chipset openWRT modem router 3g 4g, US 35 - 99 / Piece, 3G/4G portable router, GL. Welcome to 524wifi - home of best WiFi & LTE 5G & Internet over Coax & GEPON Optical networks! 981213 has written a new spi driver that replaces 'qca,ar7100-spi' for the newer atheros/qualcomm SoCs.
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donghogshock · 3 years ago
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Đồng hồ Casio G-Shock GBD-200UU-9DR
Đồng hồ Casio G-Shock GBD-200UU-9DR dành cho nam thuộc dòng G-SQUAD mỏng nhất, dây nhựa, mặt vuông, kết nối điện thoại thông minh, chức năng đếm bước, chống nước WR20BAR, Kích thước vỏ: 49,4 × 45,9 × 15mm
Dòng đồng hồ G-Shock GBD-200 là đồng hồ thể dục có liên kết điện thoại thông minh Bluetooth và cảm biến gia tốc để đếm bước. Giống như GBD-100, độ chính xác của bộ đếm bước có thể được cải thiện bằng cách sử dụng nó khi được kết nối với điện thoại thông minh được trang bị GPS và nó sẽ hiệu chỉnh phù hợp cho các phiên ngoại tuyến trong tương lai.
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Các tính năng khác đồng hồ Casio nam bao gồm khả năng chống sốc, chống nước ở độ sâu 200 mét, màn hình MIP LCD, giờ thế giới 38 thành phố (38 múi giờ với cài đặt DST tự động + UTC), đồng hồ bấm giờ (khoảng tăng 1 giây, tối đa 99: 59'59 với thời gian trôi qua và chia thời gian), đồng hồ đếm ngược (lên đến 5 bộ hẹn giờ với tính năng tự động lặp lại cho khoảng thời gian, có thể cài đặt theo khoảng tăng 1 giây, tối đa 60 phút cho mỗi bộ hẹn giờ, tự động khởi động), 4 chế độ báo hàng ngày với 1 lần báo lại, nút bật / tắt âm thanh, Super Đèn LED chiếu sáng với phát sáng sau (1,5 hoặc 3 giây), chế độ trên máy bay và chức năng rung.
https://casiovietnam.net/dong-ho-casio-g-shock-gbd-200uu-9dr-day-nhua-bo-dem-buoc-chan-ket-noi-dien-thoai-wr20bar
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anakinsthot · 3 months ago
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The first two screenshots are a little misleading. We see “99% of tested brains” but because we can’t see the source of the screenshot or it’s citations there’s no clue to how many deceased former players participated in/donated their bodies to this science. There’s likely a high bias towards men who were affected donating their brains to be studied.
The second screenshot is also a bit misleading. They did not kill themselves so they could be studied. That study would not have been approved. They did make sure not to damage their brains so they could still be studied. Is this horrific? Yes, but I think not as horrific as thinking someone killed themself just for science.
Is American football one of the worst sports for TBI incidence? Yes. There’s also meta-analysis of published studies ranking rugby higher than American football in concussion incidence, and ice hockey is consistently just behind football - and not by a lot. (For all the people in the notes going oh it’s American football not soccer… yeah soccer is the leading cause of concussions for women in sport)
What muddies the waters a lot is that currently there are few international studies or reviews. Football is the most popular sport in the US and the most studied. Don’t confuse the heightened awareness of the risk around American football to mean other sports are safe.
If you want to enact change? Don’t just go around saying “oh no no one should ever play football again” because you know that’s not going to work.
I witnessed an accident at the top level in my sport (Eventing) that put someone in a coma. It’s been months and I don’t think she’s woken up. I sold a horse to someone and found out she died a year later in an accident during competition. Regardless, I’m still committed to reaching the top levels. Because unfortunately risk doesn’t put people off of participating in sports they enjoy.
If you have kids in sports/play sports yourself make sure you and your coaches are aware of concussion protocol. https://www.sportconcussionlibrary.com this website is a great resource. If you or someone you know has a concussion for the love of god make sure you follow recovery protocol.
If you’re involved in a sport find out who is doing safety research on it - I guarantee there’s someone - and donate to it if you can. Be risk aware. Wear your safety gear and please please please replace helmets after they’ve suffered an impact or are past their expiration date.
If you’re involved with a team that uses helmets - try and get them all switched to MIPS helmets. It’s a great technology https://mipsprotection.com
And DEMAND transparency from your sports regulatory bodies. Write to, call, email the boards of directors and safety committees. Ask for helmet safety standards that include testing rotational forces.
Every sport should have guidelines to take athletes out of play if they suspect a concussion. Push to have these guidelines ENFORCED. Every sport should have incident data available every year. Some organizations are good at this and some are terrible. If you can’t find it - ask why.
man how the hell is this stupid ass sport legal. why do we funnel HIGH SCHOOLERS into this
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mewguca · 3 months ago
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i forgot to post this here. i made them a new tupper pfp (it looks Okay!)
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medicalmary · 4 years ago
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CBD and the immune system: 4 ways CBD oil provides a virus-season boost
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For CBD and the immune system, this article covers four ways in which CBD oil may support immune health
The endocannabinoid system is known to play an important role in regulating immunity and scientists consider it to be one of the “gatekeepers” of the immune system.1 The endocannabinoid system includes receptors known as cannabinoid receptors 1 and 2 (CB1 and CB2) as well as the endogenous cannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG) and enzymes that influence the production of these endocannabinoids.
There’s scientific evidence that cells of the immune system express both CB1 and CB2, although CB2 concentrations are higher than CB1.2
How CBD and the immune system interact
Cannabidiol (CBD), a non-psychoactive component of Cannabis sativa, is a phytocannabinoid that acts on the endocannabinoid system and may have the ability to maintain a balanced and healthy immune system.*
Transient receptor potential vanilloid 2 (TRPV2), a protein that facilitates the communication of cells with their extracellular environment, plays an important role in healthy immune system function.3 CBD activates TRPV2 and also influences other transient receptor potential (TRP) channels involved in supporting immunity.3*
Hemp-based CBD oil may have both direct and indirect mechanisms for maintaining immunity.* This article covers four ways in which pairing CBD and the immune system may support immune health.
Increasing natural killer cells*
In animal studies investigating autoimmune health, CBD oil from hemp has been shown to balance the immune system by reducing the activity of T cells, B cells, and both T helper and T cytotoxic lymphocyte subsets.4* However, outside of an autoimmune arena, CBD supports the activity of natural killer (NK) cells, a type of white blood cell.4*
NK cells are a major player in the body’s response to the presence of viruses.* CBD also supports the activity of natural killer T cells, which share properties of both NK cells and T cells.* In vitro studies have shown CBD has actions of interest to people who want to maintain immune health in the liver.5*
Supporting a healthy inflammatory response*
CBD is well known for its ability to maintain a healthy inflammatory response.* In animals, CBD supports a healthy inflammatory response in the lungs.6* It also improves lung function in mice exposed to a lung irritant.*
In one study, CBD enhanced markers of healthy lungs such as decreased total lung resistance and elastance, leukocyte migration into the lungs, myeloperoxidase activity in the lung tissue, and protein concentration as well as maintenance of healthy levels of cytokines (TNF and IL-6) and chemokines (MCP-1 and MIP-2).* This could potentially assist with respiratory function.*
Maintaining a healthy gut microbiota*
A large proportion of the immune system is located in the GI tract, where there are large numbers of organized lymphoid tissue and scattered innate and adaptive effector cells.7
The gut microbiota, the collection of organisms — good and bad — found in the intestines play an important role in helping the body have a balanced immune response.8
Excessive inflammation in the gut can lead to intestinal permeability, gut microbiota dysbiosis, and an impaired intestinal immune response.9,10 One way the body counteracts this is through the endocannabinoid system. 9,10  
Like endogenous cannabinoids, CBD also has been found to support a healthy intestinal  inflammatory response in human trials.11* The key message here is that keeping the gut healthy supports overall immunity.*
A calming effect during everyday mild stress and frustration*
Ongoing psychological stress is linked to a decline in immunity.12 CBD is involved in a healthy stress response.*
Unlike endogenous cannabinoids, which work on the CB1 receptor, CBD supplementation leads to direct activation of the 5-HT1A serotonin receptor.*13,14 CBD stress-relieving properties are also related to its ability to modulate cerebral blood flow in brain regions involved in anxiety including the amygdala, hippocampus, hypothalamus and cingulate cortex.15*
In human trials, CBD was found to reduce mild stress in people giving a speech.* For example, researchers observed the effects of different doses of CBD and placebo in 57 healthy male participants performing a simulated public speaking test.16* In this double-blind study, subjects were given oral CBD at doses of 150 mg, 300 mg, or 600 mg or a placebo prior to the public speaking test. Compared with the placebo, 300 mg of CBD led to the subjects being more calm and relaxed during the speech.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
CHRIS D. MELETIS, ND, is an educator, international author and lecturer. His mission is “Changing World’s Health, One Person at a Time.” He believes that when people become educated about their bodies is the moment positive change begins. He is widely recognized as a world-renowned expert on the science of CBD and has authored 16 books and over 200 national scientific articles in such journals and magazines as Natural Health, Alternative and Complementary Therapies, Townsend Letter for Doctors and Patients, Life Extension and The Journal of Restorative Medicine. He served as dean of naturopathic medicine and chief medical officer for seven years at NUNM, the oldest naturopathic medical school in North America. He has received numerous awards, including the prestigious Physician of the Year Award by the American Association of Naturopathic Physicians; Excellence Award for his work in treating and advocating for the medically underserved; and most recently, the NUNM Hall of Fame Award. He represents TruGen3 and can be contacted at DrMeletis.com. “TruEase® is an ideal choice for people searching for a phytocannabinoid-rich hemp oil. It’s encapsulated in VESIsorb®’s patented delivery system to optimize absorption. It uses a proprietary extraction process that eliminates solvents and impurities to produce non-detectible THC content. Clinically, I depend on bioavailability for my patients, and per a 2019 article, VESIsorb® CBD after a single oral administration of the SEDDS CBD led to 4.4-fold higher blood plasma levels of CBD compared to the control CBD formula.”17
References:
Oláh A, Szekanecz Z, Bíró T. Targeting Cannabinoid Signaling in the Immune System: “High”-ly Exciting Questions, Possibilities, and Challenges. Front Immunol. 2017 Nov 10;8:1487.
Booz GW. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free Radic Biol Med. 2011 Sep 1;51(5):1054-61.
Pumroy RA, Samanta A, Liu Y, et al. Molecular mechanism of TRPV2 channel modulation by cannabidiol. Elife. 2019 Sep 30;8. pii: e48792.
Ignatowska-Jankowska B, Jankowski M, Glac W, Swiergel AH. Cannabidiol-induced lymphopenia does not involve NKT and NK cells. J Physiol Pharmacol. 2009 Oct;60 Suppl 3:99-103.
Lowe HI, Toyang NJ, McLaughlin W. Potential of Cannabidiol for the Treatment of Viral Hepatitis. Pharmacognosy Res. 2017 Jan-Mar;9(1):116-8.
Ribeiro A, Almeida VI, Costola-de-Souza C, et al. Cannabidiol improves lung function and inflammation in mice submitted to LPS-induced acute lung injury. Immunopharmacol Immunotoxicol. 2015 Feb;37(1):35-41.
Mowat, A., Agace, W. Regional specialization within the intestinal immune system. Nat Rev Immunol 14, 667-685 (2014).
Wu HJ, Wu E. The role of gut microbiota in immune homeostasis and autoimmunity. Gut Microbes. 2012 Jan 1; 3(1): 4-14.
Hornby PJ, Prouty SM. Involvement of cannabinoid receptors in gut motility and visceral perception. Br J Pharmacol. 2004 Apr;141(8):1335-45.
Cani PD, Plovier H, Van Hul M, et al. Endocannabinoids–at the crossroads between the gut microbiota and host metabolism. Nat Rev Endocrinol. 2016 Mar;12(3):133-43.
Irving PM, Iqbal T, Nwokolo C, et al. A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis. Inflamm Bowel Dis. 2018 Mar 19;24(4):714-24.
Segerstrom SC, Miller GE. Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry. Psychol Bull. 2004 Jul;130(4):601-30.
Crippa JA, Derenusson GN, Ferrari TB, et al. Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol. 2011 Jan;25(1):121-30.
Shannon S, Opila-Lehman J. Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report. Perm J. 2016 Fall;20(4):16-005.
Soares VP, Campos AC. Evidences for the Anti-panic Actions of Cannabidiol. Curr Neuropharmacol. 2017;15(2):291-9.
Linares IM, Zuardi-AW, Pereira LC, et al. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Braz J Psychiatry. 2019 Jan-Feb;41(1):9-14.
Knaub K, et al. A Novel Self-Emulsifying Drug Delivery System (SEDDS) Based on VESIsorb® Formulation Technology Improving the Oral Bioavailability of Cannabidiol in Healthy Subjects. Molecules. 2019 Aug 16;24(16):pii: E2967.
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vector2game · 4 years ago
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LET'S GO TO VECTOR 2 GENERATOR SITE! [NEW] VECTOR 2 FREE DATA CHIPS AND UPGRADE KITS Add up to 999 Data Chips and up to 99 Upgrade Kits All for Free! Real working 100% guaranteed Please share this guys HOW TO USE: 1. Go to GENERATOR SITE 2. Enter your Username/ID or Email (you don’t need to enter your password) then click CONNECT 3. Enter the amount of Data Chips and Upgrade Kits then click GENERATE, Popup Agreement click CONTINUE 4. Click VERIFY, finish verification process and check your account! Vector 2 highlights exceptional interactivity with procedurally created climate and similar movements in a tragic world. RUN FOR YOUR LIFE Slip through a gigantic and complex exploration office and attempt to get out alive – again and again. Stuff UP There's horrible run without great gear! Evaluate test cutting edge gear that will assist you with enduring longer and find approaches to update it. ADD STYLE TO YOUR SKILL Learn tricks to evade lethal snares – and do it in the most boss manner ever conceivable. #vectorgame #vector2 #runnergame #vector2garmin #runner #parkour #dystopianworld #vector2apk #dystopian #vector2online #vector2gameonline #vector2game #endlessrun #vector2mod #datachips #upgradekits #endlessrunner #vector2unity #rungame #endlessrunning #runninggame #vector2games #vector2download #vector2ios #androidgamer #iosgamer #mobilegamer #vector2android Example 02.02: Texture filtering & MIP mapping | Spare ...
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mip-dev-center · 1 month ago
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Hello! This blog exists to archive art related to the Mobile Iterator Project AU. The Mobile Iterator Project AU is a Rain World OC AU that I (mewguca) made with Jade (fauxbia). You can read the website I linked for more information and some character Logs!
Here's the in-universe mission statement:
The “Mobile Iterator Project” (MIP) is a project created and directed by a Benefactor named "No Cost Too Great" (NCTG) with the stated goal of supporting Iterators in their productivity, maintenance, and longevity, so that they can operate at maximum efficiency, even after the inevitable mass ascension. ‘MIP Units—Iterators created under the project—are created puppet-first in the "MIP Development Center" and later assigned to Local Groups, where their structures are built to support the Iterators around them. Uniquely, their personalities are heavily based around singular, specific Architects (Benefactors) who donate their memories and qualia. The exception to this is TWR, who features a more traditional personality module. In total, there are 99 MIP Units, with IDs ranging from 01 to 99.
If you have questions, feel free to ask @mewguca .
Blog Admins: @mewguca (main), @fauxbia , @cloverlady Other people that own MIP Unit OCs: Corvus, Charlie, Yuuno, Viridi, Mael, Azure (?)
[TAG GUIDE] - This helps with blog navigation; I recommend looking at it. link to other master posts.
⚠️ Content Warnings
Please read these!! You can find them on the site, too.
Frequent Depictions of Trauma and Mental Illness, Frequent Depictions of Manipulation and Emotional Abuse (including depictions similar to abusive parenting), and Memory Manipulation, Frequent Themes of Dehumanization, Identity Struggles, and Dissociation
Frequent allusions to passive suicidal ideation and occasional depictions of or allusions to self harm (THESE WILL BE TAGGED)
Depictions of Unhealthy Interpersonal Relationships (platonic and romantic)
Medical Malpractice/Abuse, Genetic Experimentation (mostly pertain to a few specific characters)
Child Endangerment/Harm to Children, Child Neglect or Abuse, Medical Abuse to Children, Child Experimentation (again I will tag these; I will specify that most of these are alluded to rather than shown directly and pertain to a few specific characters)
Cult-like Manipulation tactics, Violence and Physical Abuse, Infrequent Body Horror (eyes, wings, implied blood)
There's a good deal of sensitive content. I don't make anything sexual, but I do like to explore heavier subject matter. I will try to give warnings on specific posts and use tags. please let me know if I'm missing something important. ^^
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growinstablog · 5 years ago
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Forget Spectacles. These Glasses Live-Stream To Facebook, Instagram, Or YouTube
Snap Inc.’s Spectacles were a big disaster. As hundreds of thousands of pairs rot away in a warehouse somewhere, there are some companies out there that think they can make the social hardware concept work.
One such company – an electric skateboard brand called Acton – has created a pair of sunglasses that won’t work with Snapchat. It will, however, work with Facebook, Instagram, and YouTube – allowing you to shoot and live-stream hands-free POV video.
Ace Eyewear has an onboard 8MP camera with a 120-degree wide-angle lens that can capture video and still images with the touch of a button, and stream the content by connecting directly to your smartphone. Video captured by the glasses is lacking in quality – it’s only HD quality (1792 x 1168/24, 720P: 1280 x 720/24), but can be forgiven as the onboard Dual Core MIPS 1.2GHz processor allows you to get more footage – and not at the expense of battery life.
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In fact, the battery will last you up to 80 hours on standby, up to 90 minutes when recording to its 4GB onboard memory, or 40 minutes when live-streaming. Ace Eyewear also boasts a built-in microphone to capture sound with your videos. That’s pretty impressive, from a gadget that weighs just 50 grams.
Afraid to get it dirty? Don’t. It’s IP55-rated waterproof and dust-proof, and, unlike Spectacles, you can use it to stream on three different platforms – not just one, and not just for 30 seconds. If it works as advertised, it’s a bargain!
A pair will cost you $99 if you decide to pre-order, but when released it will cost a cool $199. Pre-order now and in summer 2018 it will be yours.
#Ace Eyewear#Facebook#live#live streaming#smart glasses#snapchat#Youtube
https://growinsta.xyz/forget-spectacles-these-glasses-live-stream-to-facebook-instagram-or-youtube/
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linkandorf · 8 years ago
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As a kid I had these books where you had to find specific bugs or sea creatures in a huge scene filled with animals. In the back of the book, there was versions of each picture where all the creatures were silhouetted and numbered, along with a guide to help you find where certain creatures are. So that’s what this is. I guess this can be helpful if you either don’t recognize a character and want to find their name, or cant find a certain character in the picture. I noticed that there was 118 characters, so I decided to include my signature at the bottom right and the SM64 logo at the top because having 120 things is too perfect.
1. Fly Guy 2. Pokey 3. Micro Goomba 4. Thwomp 5. Mario 6. Wing Mario 7. Tuxie the Baby Penguin 8. Bully 9. Big Boo 10. Monty Mole 11. Bub / Cheep Cheep 12. Wing Cap 13. Clam 14. Metal Mario 15. Spindel 16. Headless Snowman’s Head 17. Vanish Mario 18. Bird 19. Koopa Troopa 20. Red ! Block 21. Swoop 22. Small Koopa Troopa 23. Big Penguin 24. Beach Koopa 25. Unagi the Eel 26. Bullet Bill and Bill Blaster 27. Piranha Plant 28. Crazed Crate 29. Fish #1 30. Boulder / Watch Out for Falling Rocks! 31. Star Marker (Where the Red Coin Star appears) 32. Coin 33. Amp 34. Mr. I 35. Snufit 36. Bob-Omb 37. Bookend 38. Princess Toadstool~ Peach 39. Blue ! Switch 40. Key 41. Whomp 42. Kuromame 43. Toad 44. Giant Snowman in Snowman’s Land 45. Bob-Omb Buddy 46. Magic Carpet 47. Chain Chomp 48. Spinning Heart 49. Grindel 50. Bomp 51. Ukiki 52. Green ! Switch 53. Mama Penguin 54. Power Star 55. Moneybag 56. Big Mr. I 57. Green ! Block 58. Crystal Tap 59. Chuckya 60. Big Bully 61. Venus Fire Trap / Small Venus Fire Trap / Fire Piranha / I’m not sure what they’re called tbh /  62. Blue Coin 63. Big Goomba 64. Yellow ! Block 65. Lakitu Bro. #1 66. Skeeter 67. Big Bob-Omb / King Bob-Omb 68. MIPS the Rabbit 69. Blue Switch 70. Water Bomb 71. Skull Crate 72. Fwoosh 73. Klepto 74. Cannon 75. Lakitu Bro. #2 76. Red Coin 77. Floating Mine 78. Butterfly 79. Big Venus Fire Trap / Big Fire Piranha 80. Metal Cap 81. Arrow Lift 82. Koopa the Quick 83. Scuttlebug (no memes here) 84. Wiggler 85. Heave-Ho 86. Hoot the Owl 87. Bird That Carries You Over A Disproportionately Small Gap Boo That Carries The Cage That Takes You To Big Boo’s Haunt 88. Headless Snowman’s Body 89. Fish #2 90. Sushi 91. Chill Bully 92. Red ! Switch 93. Tweester / Tornado 94. Mad Piano 95. Yoshi 96. Killer Chair 97. Purple Switch 98. Big Power Star 99. Lakitu 100. Mr. Blizzard 101. Bowser 102. Lava Bubble 103. Big Steely / just a big ol metal ball 104. Dorrie 105. Spiny 106. Manta 107. Tox Box 108. Goomba 109. Whomp King 110. Shiny Shell 111. Boo 112. Eyerok 113. Bubba / Boss Bass 114. Blue ! Block 115. 1-Up Mushroom 116. Spindrift 117. Vanish Cap 118. Fire Jet 119. My Signature UwU 120. Super Mario 64 Logo
hopefully people use this and i didnt waste my time hahahaha (jokes on you i had fun)
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