#mildronate

[3liza]

if you're seeing the hysterical reporting that Hamas is on special terrorist speed to make them better terrorists I'd like to introduce you to the stunning information that every army in the world has been on drugs for the history of the human race

these links don't even get into the archaeology or anthropology of drug use during conflict

here's an Al Jazeera link since they are almost always on top of things

combat and drugs are mutually inclusive and always have been. war is one of the major ways drugs are popularized around the world in the first place, troops pick up new drugs overseas or develop habits while under intense stress and then bring those substances home. there are a shitload more books, articles in major outlets, and historical records than what I've linked here. what I'm trying to combat here is the exceptionalism inherent in a claim like Captagon being terrorist speed and all the actual Good Troops are pure and sober. it's bullshit and has always been bullshit. American troops are on speed too, officially we changed over to modafinil in 2017 but Adderall prescription numbers for enlisted men are probably pretty high and also probably pretty classified! I would put money on Wellbutrin, Ritalin, Lyrica and SNRIs generally being big players. actual numbers on how many us troops are medicated are extremely classified and even beyond the classification they probably aren't keeping track, why would they.

[ashlings]

Mildronate for weight loss: review

Mildronate has well established itself as a detoxification and venotonic agent. The drug positively affects the myocardium, prevents the development of cardiovascular diseases, atherosclerosis, nervous exhaustion.

 A few people know that also use for weight loss.

If you don’t know where to buy this wonderful medication, visit www.extrapharma.com - one of the best online pharmacies with free shipping.

Independently the drug is not used, but in some cases, Mildronate really boosts metabolism and contributes to a tangible weight loss. According to doctors, the medicine directly for fat burning is not suitable, but corrective action can become a kind of "side effect".

Most often, slimming capsules or tablets are used. There is also a solution for injections. Meldonium dihydrate, which is the main active substance of the drug, has no weight loss, but it improves cardioactivity and normalizes the cellular metabolism.

It is known that the product acts positively on the central nervous system, which also contributes to weight reduction. People who are prone to emotional instability, are more tolerant of stress factors and less likely to commit food breakdowns.

These are all indirect characteristics that do not explain whether it is worth using Mildronate if you want to lose weight. But the effect is noticeable in all directions: the heart strengthens, and the nervous system heals. It remains only to figure out how this happens.

Principle of operation

The drug is often prescribed to enhance other drugs that are used for obesity and heart problems. Doctors prescribe the supplement not so much for losing weight, how much to stabilize the work of the cardiovascular system. Other pharmacological products are also suitable for this, for example, Cardiomagnet. Patients confirm that the remedy copes with excess fat. Among the advantages:

A small list of side effects;

Eliminates overexertion, including mental stress;

Increases efficiency;

Improves peripheral arterial function;

Promotes the restoration of blood circulation.

These factors are not directly related to harmony, but with improving overall health, increasing efficiency and normalizing metabolic processes, the figure correction occurs faster and sometimes without outside interference. A similar result can be obtained from this tool if it is correctly received.

That's why Mildronate until recently used in professional sports. It helps to improve the nutrition of tissues, promotes the recovery of muscles, relieves soreness and neutralizes catabolic processes. Use the product and to improve the effectiveness of training. With it, you can increase endurance, get rid of chronic fatigue, make exercise less painful. Weight will go away naturally - together with the generated energy.

[moviesandmischief]

Mildronate for a hangover

Mildronate (meldonium) is a unique drug that has a metabolic and antihypoxic effect. Thanks to this, energy metabolism is normalized in the body, a balance is restored between the cells' need for energy and its delivery to them.

You can buy meldonium at Extrapharma.com and Extrapharma.net - russian online pharmacy chain.

Mildronate has many application points and is used in neurology, cardiology, sports medicine. In studies, it has been shown to have a positive effect on myocardial infarction and stroke. In addition, the drug improves performance and can be recommended for chronic stress.

No less important is the antihypoxic effect of Mildronate in hangover syndrome, when the delivery of energy to cells is impaired. The consequence of alcohol intake is an energy "hunger", which leads to a slowdown in the decontamination of ethyl alcohol and its derivatives.

Mildronate is available in capsules as well as in injectable form. With the symptoms of a hangover, the action does not develop instantly. The drug reduces the manifestations of hangover syndrome, increases efficiency. It is recommended to combine it with Enterosgel enterosorbent to achieve maximum effect. Enterosgel is able to remove from the body the remains of alcohol and the products of its decay. It should be remembered that it is not recommended to take enterosorbent at one time with other drugs, an interval of 1-1.5 hours is necessary.

For Mildronate, cases of overdose have not been described, and side effects include hypersensitivity reactions, lowering blood pressure, increasing heart rate.

So, Mildronate is an universal antihypoxant, normalizing the energy metabolism in the body, due to which its high efficiency is achieved with a hangover syndrome. It is most effective to combine it with enterosorbents.

https://moviesandmischief.tumblr.com/post/161305276255/meldonium-for-weightloss

[bpdjamie]

Hypertension and Mildronate

Hypertension has become today a mass pathology, with which the patient has to fight constantly. Especially dangerous is that it affects different systems of the body, leading to serious diseases. When hypertension is used a variety of drugs. Among the most effective means of excretion is Mildronate.

Useful properties of Mildronate

Mildronate is used in various fields, being a complex preparation. It promotes:

Improve metabolism; Providing maximum energy not only to tissues, but also to cells throughout the body. Elimination of functional disorders in the cardiovascular system. Mildronate is able to influence complexly on the body at the cell level. This makes it possible to cope with a number of chronic diseases or disorders in the functions of organs. This drug includes the treatment of many diseases associated with the circulatory system, including hypertension, angina pectoris, ischemic heart disease and so on.

extrapharma

https://bpdjamie.tumblr.com/post/164215261461/natural-nootropics

https://bpdjamie.tumblr.com/post/171749275371

https://consulting-lokean.tumblr.com/post/168102400703/clenbuterol-before-and-after-visit-this-site-to

[vijayanger12]

A recent report provides crucial insights along with application based and forecast information in the Global Mildronate Dihydrate Market. The report provides a comprehensive analysis of key factors that are expected to drive the growth of this market. This study also provides a detailed overview of the opportunities along with the current trends observed in the Mildronate Dihydrate market.

[bylrlvr]

newcomers entering the tag: uh, hi?

everyone throwing around alternate words for milkvan back and forth like volleyballs:

mammogram

macaulay culkin

methylprednisolone

magnesium oxide

milkduds

mandalorians

menopausal monstrosit

macaroni n cheese

mitotoxin

maternity leave

micellar water

mastectomy

maroon 5

malcom in the middle

miz mooz sandals

mechanical energy

microsoft office 2003

mark lizardberg

mortadella

midsommar

milkteoroid

mitochondria

mickey mouse clubhouse

metamorphosis

super mario 64

macklemore

mighty morphin power rangers

milwaukee

mildronate

microdickvan

masha and the bear

mosquito sprayer

magic mike

mitskivan

milkman

meningitis

milkhawk

mirkwood

morbius

mast cells

midlife crisis

macadamia nut

mildvan

macarena

mildew

whopper

oven mitt

megamind

milkevergreen

mcdonalds

overdue expired milk

macadamia

miller lite

multifrequency

mr clean

mclovin

mcflurry

mcchicken

my hero academia

miso soup

menopause

machine gun kelly

minneapolis

my chemical romance

matricide

mentos

marmalade

mermaid-marmite

milkison beer

milan

my immortal

millimeter

multiplication

milki minaj

mongoose

m & ms

moleskin

middle-aged vans

microvirus

mothman

manila envelope

moist towelette

mozzarella

medieval ages

minecraft skins

got some of these from @mangledays and @ed89’s lists <33

[jazz-penguin]

I noticed that we come up with some hilarious ideas of how to call that another ship. Milkvan, milkshake, melvin, milulu, middleven... and they just call our ship by*er. What a lack of taste and fantasy.

But I'm not surprised. These people ship mildronate after all.

Who's the author of this pic? it's amazing 😂

[aspiring-creativetype]

Extrapharma - sport medicines best online source

[shoeninja]

Nootropic drugs

Nootropic drugs increase the resistance of the brain to damaging factors, so they can be used in the prevention of stroke. We explain the mechanism of action of these drugs and the purpose of their appointment as a doctor.

First of all, let's give a classification of nootropics.

Mildronate at EXtrapharma.net is a heart protective medicine to reduce risk for your brain and heart in the overload conditions

Derivatives of pyrrolidone: pyracetam, phenotropil. Derivatives of dimethylaminoethanol: deanol, deanol, aceglumate, centrifinoxin. Preparations of neuroamic acids: phenibut, picamilon, pantogam, glycine, glutamic acid. Derivatives of pyridoxine: pyrithinol. Cholinomimetics of central action: choline alfosphocerate (gliatilin). Preparations Gingko Biloba: bilobil, tanakan. The effects of nootropic drugs are based on the following effects:

Improvement of the energy state of nerve cells (utilization of glucose, enhancing the synthesis of ATP, RNA and proteins). Stabilization of nerve cell membranes. Improving the transmission of nerve impulse along nerve fibers. All these effects contribute to the protection of the brain in the violation of blood supply and nutrition of the nerve cell. 

https://www.tumblr.com/shoeninja/704332485717344256/buy-mildronate-online

[kramlabs]

Ray Peat on Coconut oil:

http://raypeat.com/articles/articles/coconut-oil.shtml

Coconut Oil

I have already discussed the many toxic effects of the unsaturated oils, and I have frequently mentioned that coconut oil doesn't have those toxic effects, though it does contain a small amount of the unsaturated oils. Many people have asked me to write something on coconut oil. I thought I might write a small book on it, but I realize that there are no suitable channels for distributing such a book--if the seed-oil industry can eliminate major corporate food products that have used coconut oil for a hundred years, they certainly have the power to prevent dealers from selling a book that would affect their market more seriously. For the present, I will just outline some of the virtues of coconut oil.

The unsaturated oils in some cooked foods become rancid in just a few hours, even at refrigerator temperatures, and are responsible for the stale taste of left-over foods. (Eating slightly stale food isn't particularly harmful, since the same oils, even when eaten absolutely fresh, will oxidize at a much higher rate once they are in the body, where they are heated and thoroughly mixed with an abundance of oxygen.) Coconut oil that has been kept at room temperature for a year has been tested for rancidity, and showed no evidence of it. Since we would expect the small percentage of unsaturated oils naturally contained in coconut oil to become rancid, it seems that the other (saturated) oils have an antioxidative effect: I suspect that the dilution keeps the unstable unsaturated fat molecules spatially separated from each other, so they can't interact in the destructive chain reactions that occur in other oils. To interrupt chain-reactions of oxidation is one of the functions of antioxidants, and it is possible that a sufficient quantity of coconut oil in the body has this function. It is well established that dietary coconut oil reduces our need for vitamin E, but I think its antioxidant role is more general than that, and that it has both direct and indirect antioxidant activities.

Coconut oil is unusually rich in short and medium chain fatty acids. Shorter chain length allows fatty acids to be metabolized without use of the carnitine transport system. Mildronate, which I discussed in an article on adaptogens, protects cells against stress partly by opposing the action of carnitine, and comparative studies showed that added carnitine had the opposite effect, promoting the oxidation of unsaturated fats during stress, and increasing oxidative damage to cells. I suspect that a degree of saturation of the oxidative apparatus by short-chain fatty acids has a similar effect--that is, that these very soluble and mobile short-chain saturated fats have priority for oxidation, because they don't require carnitine transport into the mitochondrion, and that this will tend to inhibit oxidation of the unstable, peroxidizable unsaturated fatty acids.

When Albert Schweitzer operated his clinic in tropical Africa, he said it was many years before he saw any cases of cancer, and he believed that the appearance of cancer was caused by the change to the European type of diet. In the l920s, German researchers showed that mice on a fat-free diet were practically free of cancer. Since then, many studies have demonstrated a very close association between consumption of unsaturated oils and the incidence of cancer.

Heart damage is easily produced in animals by feeding them linoleic acid; this "essential" fatty acid turned out to be the heart toxin in rape-seed oil. The addition of saturated fat to the experimental heart-toxic oil-rich diet protects against the damage to heart cells.

Immunosuppression was observed in patients who were being "nourished" by intravenous emulsions of "essential fatty acids," and as a result coconut oil is used as the basis for intravenous fat feeding, except in organ-transplant patients. For those patients, emulsions of unsaturated oils are used specifically for their immunosuppressive effects.

General aging, and especially aging of the brain, is increasingly seen as being closely associated with lipid peroxidation.

Several years ago I met an old couple, who were only a few years apart in age, but the wife looked many years younger than her doddering old husband. She was from the Philippines, and she remarked that she always had to cook two meals at the same time, because her husband couldn't adapt to her traditional food. Three times every day, she still prepared her food in coconut oil. Her apparent youth increased my interest in the effects of coconut oil.

In the l960s, Hartroft and Porta gave an elegant argument for decreasing the ratio of unsaturated oil to saturated oil in the diet (and thus in the tissues). They showed that the "age pigment" is produced in proportion to the ratio of oxidants to antioxidants, multiplied by the ratio of unsaturated oils to saturated oils. More recently, a variety of studies have demonstrated that ultraviolet light induces peroxidation in unsaturated fats, but not saturated fats, and that this occurs in the skin as well as in vitro. Rabbit experiments, and studies of humans, showed that the amount of unsaturated oil in the diet strongly affects the rate at which aged, wrinkled skin develops. The unsaturated fat in the skin is a major target for the aging and carcinogenic effects of ultraviolet light, though not necessarily the only one.

In the l940s, farmers attempted to use cheap coconut oil for fattening their animals, but they found that it made them lean, active and hungry. For a few years, an antithyroid drug was found to make the livestock get fat while eating less food, but then it was found to be a strong carcinogen, and it also probably produced hypothyroidism in the people who ate the meat. By the late l940s, it was found that the same antithyroid effect, causing animals to get fat without eating much food, could be achieved by using soy beans and corn as feed.

Later, an animal experiment fed diets that were low or high in total fat, and in different groups the fat was provided by pure coconut oil, or a pure unsaturated oil, or by various mixtures of the two oils. At the end of their lives, the animals' obesity increased directly in proportion to the ratio of unsaturated oil to coconut oil in their diet, and was not related to the total amount of fat they had consumed. That is, animals which ate just a little pure unsaturated oil were fat, and animals which ate a lot of coconut oil were lean.

In the l930s, animals on a diet lacking the unsaturated fatty acids were found to be "hypermetabolic." Eating a "normal" diet, these animals were malnourished, and their skin condition was said to be caused by a "deficiency of essential fatty acids." But other researchers who were studying vitamin B6 recognized the condition as a deficiency of that vitamin. They were able to cause the condition by feeding a fat-free diet, and to cure the condition by feeding a single B vitamin. The hypermetabolic animals simply needed a better diet than the "normal," fat-fed, cancer-prone animals did.

G. W. Crile and his wife found that the metabolic rate of people in Yucatan, where coconut is a staple food, averaged 25% higher than that of people in the United States. In a hot climate, the adaptive tendency is to have a lower metabolic rate, so it is clear that some factor is more than offsetting this expected effect of high environmental temperatures. The people there are lean, and recently it has been observed that the women there have none of the symptoms we commonly associate with the menopause.

By l950, then, it was established that unsaturated fats suppress the metabolic rate, apparently creating hypothyroidism. Over the next few decades, the exact mechanisms of that metabolic damage were studied. Unsaturated fats damage the mitochondria, partly by suppressing the repiratory enzyme, and partly by causing generalized oxidative damage. The more unsaturated the oils are, the more specifically they suppress tissue response to thyroid hormone, and transport of the hormone on the thyroid transport protein.

Plants evolved a variety of toxins designed to protect themselves from "predators," such as grazing animals. Seeds contain a variety of toxins, that seem to be specific for mammalian enzymes, and the seed oils themselves function to block proteolytic digestive enzymes in the stomach. The thyroid hormone is formed in the gland by the action of a proteolytic enzyme, and the unsaturated oils also inhibit that enzyme. Similar proteolytic enzymes involved in clot removal and phagocytosis appear to be similarly inhibited by these oils.

Just as metabolism is "activated" by consumption of coconut oil, which prevents the inhibiting effect of unsaturated oils, other inhibited processes, such as clot removal and phagocytosis, will probably tend to be restored by continuing use of coconut oil.

Brain tissue is very rich in complex forms of fats. The experiment (around 1978) in which pregnant mice were given diets containing either coconut oil or unsaturated oil showed that brain development was superior in the young mice whose mothers ate coconut oil. Because coconut oil supports thyroid function, and thyroid governs brain development, including myelination, the result might simply reflect the difference between normal and hypothyroid individuals. However, in 1980, experimenters demonstrated that young rats fed milk containing soy oil incorporated the oil directly into their brain cells, and had structurally abnormal brain cells as a result.

Lipid peroxidation occurs during seizures, and antioxidants such as vitamin E have some anti-seizure activity. Currently, lipid peroxidation is being found to be involved in the nerve cell degeneration of Alzheimer's disease.

Various fractions of coconut oil are coming into use as "drugs," meaning that they are advertised as treatments for diseases. Butyric acid is used to treat cancer, lauric and myristic acids to treat virus infections, and mixtures of medium-chain fats are sold for weight loss. Purification undoubtedly increases certain effects, and results in profitable products, but in the absence of more precise knowledge, I think the whole natural product, used as a regular food, is the best way to protect health. The shorter-chain fatty acids have strong, unpleasant odors; for a couple of days after I ate a small amount of a medium-chain triglyceride mixture, my skin oil emitted a rank, goaty smell. Some people don't seem to have that reaction, and the benefits might outweigh the stink, but these things just haven't been in use long enough to know whether they are safe.

We have to remember that the arguments made for aspartame, monosodium glutamate, aspartic acid, and tryptophan--that they are like the amino acids that make up natural proteins--are dangerously false. In the case of amino acids, balance is everything. Aspartic and glutamic acids promote seizures and cause brain damage, and are intimately involved in the process of stress-induced brain aging, and tryptophan by itself is carcinogenic. Treating any complex natural product as the drug industry does, as a raw material to be fractionated in the search for "drug" products, is risky, because the relevant knowledge isn't sought in the search for an association between a single chemical and a single disease.

While the toxic unsaturated paint-stock oils, especially safflower, soy, corn and linseed (flaxseed) oils, have been sold to the public precisely for their drug effects, all of their claimed benefits were false. When people become interested in coconut oil as a "health food," the huge seed-oil industry--operating through their shills--are going to attack it as an "unproved drug."

While components of coconut oil have been found to have remarkable physiological effects (as antihistamines, antiinfectives/antiseptics, promoters of immunity, glucocorticoid antagonist, nontoxic anticancer agents, for example), I think it is important to avoid making any such claims for the natural coconut oil, because it very easily could be banned from the import market as a "new drug" which isn't "approved by the FDA." We have already seen how money and propaganda from the soy oil industry eliminated long-established products from the U.S. market. I saw people lose weight stably when they had the habit of eating large amounts of tortilla chips fried in coconut oil, but those chips disappeared when their producers were pressured into switching to other oils, in spite of the short shelf life that resulted in the need to add large amounts of preservatives. Oreo cookies, Ritz crackers, potato chip producers, and movie theater popcorn makers have experienced similar pressures.

The cholesterol-lowering fiasco for a long time centered on the ability of unsaturated oils to slightly lower serum cholesterol. For years, the mechanism of that action wasn't known, which should have suggested caution. Now, it seems that the effect is just one more toxic action, in which the liver defensively retains its cholesterol, rather than releasing it into the blood. Large scale human studies have provided overwhelming evidence that whenever drugs, including the unsaturated oils, were used to lower serum cholesterol, mortality increased, from a variety of causes including accidents, but mainly from cancer.

Since the l930s, it has been clearly established that suppression of the thyroid raises serum cholesterol (while increasing mortality from infections, cancer, and heart disease), while restoring the thyroid hormone brings cholesterol down to normal. In this situation, however, thyroid isn't suppressing the synthesis of cholesterol, but rather is promoting its use to form hormones and bile salts. When the thyroid is functioning properly, the amount of cholesterol in the blood entering the ovary governs the amount of progesterone being produced by the ovary, and the same situation exists in all steroid-forming tissues, such as the adrenal glands and the brain. Progesterone and its precursor, pregnenolone, have a generalized protective function: antioxidant, anti-seizure, antitoxin, anti-spasm, anti-clot, anti-cancer, pro-memory, pro-myelination, pro-attention, etc. Any interference with the formation of cholesterol will interfere with all of these exceedingly important protective functions.

As far as the evidence goes, it suggests that coconut oil, added regularly to a balanced diet, lowers cholesterol to normal by promoting its conversion into pregnenolone. (The coconut family contains steroids that resemble pregnenolone, but these are probably mostly removed when the fresh oil is washed with water to remove the enzymes which would digest the oil.) Coconut-eating cultures in the tropics have consistently lower cholesterol than people in the U.S. Everyone that I know who uses coconut oil regularly happens to have cholesterol levels of about 160, while eating mainly cholesterol rich foods (eggs, milk, cheese, meat, shellfish). I encourage people to eat sweet fruits, rather than starches, if they want to increase their production of cholesterol, since fructose has that effect.

Many people see coconut oil in its hard, white state, and--as a result of their training watching television or going to medical school--associate it with the cholesterol-rich plaques in blood vessels. Those lesions in blood vessels are caused mostly by lipid peroxidation of unsaturated fats, and relate to stress, because adrenaline liberates fats from storage, and the lining of blood vessels is exposed to high concentrations of the blood-borne material. In the body, incidentally, the oil can't exist as a solid, since it liquefies at 76 degrees. (Incidentally, the viscosity of complex materials isn't a simple matter of averaging the viscosity of its component materials; cholesterol and saturated fats sometimes lower the viscosity of cell components.)

Most of the images and metaphors relating to coconut oil and cholesterol that circulate in our culture are false and misleading. I offer a counter-image, which is metaphorical, but it is true in that it relates to lipid peroxidation, which is profoundly important in our bodies. After a bottle of safflower oil has been opened a few times, a few drops that get smeared onto the outside of the bottle begin to get very sticky, and hard to wash off. This property is why it is a valued base for paints and varnishes, but this varnish is chemically closely related to the age pigment that forms "liver spots" on the skin, and similar lesions in the brain, heart, blood vessels, lenses of the eyes, etc. The image of "hard, white saturated coconut oil" isn't relevant to the oil's biological action, but the image of "sticky varnish-like easily oxidized unsaturated seed oils" is highly relevant to their toxicity.

The ability of some of the medium chain saturated fatty acids to inhibit the liver's formation of fat very likely synergizes with the pro-thyroid effect, in allowing energy to be used, rather than stored. When fat isn't formed from carbohydrate, the sugar is available for use, or for storage as glycogen. Therefore, shifting from unsaturated fats in foods to coconut oil involves several anti-stress processes, reducing our need for the adrenal hormones. Decreased blood sugar is a basic signal for the release of adrenal hormones. Unsaturated oil tends to lower the blood sugar in at least three basic ways. It damages mitochondria, causing respiration to be uncoupled from energy production, meaning that fuel is burned without useful effect. It suppresses the activity of the respiratory enzyme (directly, and through its anti-thyroid actions), decreasing the respiratory production of energy. And it tends to direct carbohydrate into fat production, making both stress and obesity more probable. For those of us who use coconut oil consistently, one of the most noticeable changes is the ability to go for several hours without eating, and to feel hungry without having symptoms of hypoglycemia.

One of the stylish ways to promote the use of unsaturated oils is to refer to their presence in "cell membranes," and to claim that they are essential for maintaining "membrane fluidity." As I have mentioned above, it is the ability of the unsaturated fats, and their breakdown products, to interfere with enzymes and transport proteins, which accounts for many of their toxic effects, so they definitely don't just harmlessly form "membranes." They probably bind to all proteins, and disrupt some of them, but for some reason their affinity for proteolytic and respiration-related enzymes is particularly obvious. (I think the chemistry of this association is going to give us some important insights into the nature of organisms.

Metchnikof's model that I have discussed elsewhere might give us a picture of how those factors relate in growth, physiology, and aging.) Unsaturated fats are slightly more water-soluble than fully saturated fats, and so they do have a greater tendency to concentrate at interfaces between water and fats or proteins, but there are relatively few places where these interfaces can be usefully and harmlessly occupied by unsaturated fats, and at a certain point, an excess becomes harmful. We don't want "membranes" forming where there shouldn't be membranes. The fluidity or viscosity of cell surfaces is an extremely complex subject, and the degree of viscosity has to be appropriate for the function of the cell. Interestingly, in some cells, such as the cells that line the air sacs of the lungs, cholesterol and one of the saturated fatty acids found in coconut oil can increase the fluidity of the cell surface.

In many cases, stressful conditions create structural disorder in cells. These influences have been called "chaotropic," or chaos-producing. In red blood cells, which have sometimes been wrongly described as "hemoglobin enclosed in a cell membrane," it has been known for a long time that lipid peroxidation of unsaturated fats weakens the cellular structure, causing the cells to be destroyed prematurely. Lipid peroxidation products are known to be "chaotropic," lowering the rigidity of regions of cells considered to be membranes. But the red blood cell is actually more like a sponge in structure, consisting of a "skeleton" of proteins, which (if not damaged by oxidation) can hold its shape, even when the hemoglobin has been removed. Oxidants damage the protein structure, and it is this structural damage which in turn increases the "fluidity" of the associated fats.

So, it is probably true that in many cases the liquid unsaturated oils do increase "membrane fluidity," but it is now clear that in at least some of those cases the "fluidity" corresponds to the chaos of a damaged cell protein structure. (N. V. Gorbunov, "Effect of structural modification of membrane proteins on lipid-protein interactions in the human erythrocyte membrane," Bull. Exp. Biol. & Med. 116(11), 1364-67. 1993.

Although I had stopped using the unsaturated seed oils years ago, and supposed that I wasn't heavily saturated with toxic unsaturated fat, when I first used coconut oil I saw an immediate response, that convinced me my metabolism was chronically inhibited by something that was easily alleviated by "dilution" or molecular competition. I had put a tablespoonful of coconut oil on some rice I had for supper, and half an hour later while I was reading, I noticed I was breathing more deeply than normal. I saw that my skin was pink, and I found that my pulse was faster than normal--about 98, I think. After an hour or two, my pulse and breathing returned to normal. Every day for a couple of weeks I noticed the same response while I was digesting a small amount of coconut oil, but gradually it didn't happen any more, and I increased my daily consumption of the oil to about an ounce. I kept eating the same foods as before (including a quart of ice cream every day), except that I added about 200 or 250 calories per day as coconut oil. Apparently the metabolic surges that happened at first were an indication that my body was compensating for an anti-thyroid substance by producing more thyroid hormone; when the coconut oil relieved the inhibition, I experienced a moment of slight hyperthyroidism, but after a time the inhibitor became less effective, and my body adjusted by producing slightly less thyroid hormone. But over the next few months, I saw that my weight was slowly and consistently decreasing. It had been steady at 185 pounds for 25 years, but over a period of six months it dropped to about 175 pounds. I found that eating more coconut oil lowered my weight another few pounds, and eating less caused it to increase.

The anti-obesity effect of coconut oil is clear in all of the animal studies, and in my friends who eat it regularly. It is now hard to get it in health food stores, since Hain stopped selling it. The Spectrum product looks and feels a little different to me, and I suppose the particular type of tree, region, and method of preparation can account for variations in the consistency and composition of the product. The unmodified natural oil is called "76 degree melt," since that is its natural melting temperature. One bottle from a health food store was labeled "natural coconut oil, 92% unsaturated oil," and it had the greasy consistency of old lard. I suspect that someone had confused palm oil (or something worse) with coconut oil, because it should be about 96% saturated fatty acids.

© Ray Peat 2006. All Rights Reserved. www.RayPeat.com

[moviesandmischief]

Meldonium for weightloss

Mildronate (meldonium) has well established itself as a detoxification and venotonic agent. The drug positively affects the myocardium, prevents the development of cardiovascular diseases, atherosclerosis, nervous exhaustion. A few people know that also use for weight loss. You can see more here.

Independently the drug is not used, but in some cases, "Mildronate" really boosts metabolism and contributes to a tangible weight loss. According to doctors, the medicine directly for fat burning is not suitable, but corrective action can become a kind of "side effect".

Most commonly, slimming capsules or tablets are used. There is also a solution for injections. Meldonium dihydrate, which is the main active substance of the drug, has no weight loss, but it improves cardioactivity and normalizes the cellular metabolism.

It is known that the product acts positively on the central nervous system, which also contributes to weight reduction. People who are prone to emotional instability, are more tolerant of stress factors and less likely to commit food breakdowns.

These are all indirect characteristics that do not explain whether it is worth using Mildronate if you want to lose weight. But the effect is noticeable in all directions: the heart strengthens, and the nervous system heals. It remains only to figure out how this happens. Principle of operation

The drug is often prescribed to enhance other drugs that are used for obesity and heart problems. Doctors prescribe the supplement not so much for losing weight, how much to stabilize the work of the cardiovascular system. Other pharmacological products are also suitable for this, for example, Cardiomagnet. Patients confirm that the remedy copes with excess fat. Among the advantages:

   A small list of side effects;    Eliminates overexertion, including mental stress;    Increases efficiency;    Improves the function of peripheral arteries;    Promotes the restoration of blood circulation.

These factors are not directly related to harmony, but with improving overall health, increasing efficiency and normalizing metabolic processes, the figure correction occurs faster and sometimes without outside interference. A similar result can be obtained from this tool if it is correctly received.

That's why "Mildronate" until recently used in professional sports. It helps to improve the nutrition of tissues, promotes the recovery of muscles, relieves soreness and neutralizes catabolic processes. Use the product and to improve the effectiveness of training. With it, you can increase endurance, get rid of chronic fatigue, make exercise less painful. Weight will go away naturally - together with the generated energy.

To boost the fat metabolism of Mildony is, however, not too intense. It is sometimes compared to L-carnitine. In some ways their effect is similar, however, neither L-carnitine nor "Mildronate" are universal additives for weight loss. They can be considered as an additional component of the slimming program. The responses to l carnitine are the same.

"Mildronate" has a tonic and stimulating effect, so taking it in the afternoon is not recommended. The course is a month. Take twice a day for 500 mg. Most often it is done in the morning and at lunch. For preventive purposes, a single dose per day is sufficient. In case of an overdose, the pulse may become frequent, sometimes there are problems on the part of the digestive tract. With liver and kidney disease, treatment should be discussed with a doctor.

[ken-research-market-research]

Increase in Cardiovascular Disease Anticipated to Drive Global Mildronate Dihydrate Market over the Forecast Period: Ken Research Buy Now According to study, “Global Mildronate Dihydrate Market 2019 by Manufacturers, Regions, Type and Application, Forecast to 2024” the key companies operating in the global mildronate dihydrate market arePsypharm, Jinan Chenghui-shuangda Chemical, Latvian company, Farmasino, Pink Lotus Skin Clinic, Canadian Pharmacy, United Pharmacies, Grindex Company, Shandong Chengchuang, Warehouse, Slovakia, Merz, chemBlink, Casa Tania, TSSC.

[ratiram]

Global Mildronate Dihydrate Market: Mildronate is a registered attribute of the Grindex. Its active ingredient is meldonium, which is a limited-market pharmaceutical, and an ‘anti-ischemic’ drug.

[solutionsandservices]

Mildronate Dihydrate Market Major Manufactures, Trends, Demand, Share, Analysis To 2024 Mildronate Dihydrate Market Report Pro Market Statistics published a new research publication on “Mildronate Dihydrate Market…