#microinjections

[beakers-and-telescopes]

With the fast fashion industry… how it is… finding sustainable ways to make fabric is super important.  Fibers from synthetic fabrics make up 35% of the microplastics that make their way to the ocean.  Natural fibers sourced from plants or animals are much more environmentally sound options, including silk.

Currently, the only way to get natural silk on a large scale is to harvest it from silkworms.  You’ve probably heard about the strength and durability of spider silk (it is 6x stronger than Kevlar!) but as of yet there hasn’t been a good way of getting it.  Raising spiders the way people do silkworms isn’t really an option.  Spiders need a lot of room to build their webs compared to silkworms, and individual spiders don’t produce that much silk.  Plus, when you put a whole bunch of spiders in captivity together, they tend to start eating each other.

Attempts to artificially recreate spider silk have also been less than successful.  Spider silk has a surface layer of glycoproteins and lipids on it that works as a sort of anti-aging “skin”- allowing the silk to withstand conditions such as sunlight and humidity.  But this layer has been very tricky to reproduce.

However, as scientists in China realized, silkworms produce that same kind of layer on their silk.  So what if we just genetically modified silkworms to produce spider silk?

That is exactly what the researchers at Donghua University in Shanghai did.  A team of researchers introduced spider silk protein genes to silkworms using CRISPR-Cas9 gene editing and microinjections in silkworm eggs.  In addition to this, they altered the spider silk proteins so that they would interact properly with the other proteins in silkworm glands.  And it worked!  This is the first study ever to produce full length spider silk proteins from silkworms.

The applications of this are incredibly exciting.  In addition to producing comfortable textiles and new, innovative bulletproof vests, silkworm generated spider silk could be used in cutting edge smart materials or even just to create better performing sutures.  In the future, this team intends to research how to modify this new spider silk to be even stronger, and they are confident that “large-scale commercialization is on the horizon."

[dreamgrlarchive]

High Maintenance 101

Prissy Girl Beauty Regimens 🎀

my prissy girl guide to beauty services and building a beauty lifestyle that fits you 💗

Skincare:

Essential Skincare Routine ❤︎︎

twice daily, in the morning and at night

daytime: gentle cleanser, toner, serum, eye cream, moisturizer, SPF

prep and protect skin

nighttime: double cleansing with oil and cleanser, exfoliation, treatments, moisturizer

wash away the day and help skin accept treatments and actives during your beauty sleep

products will change depending on skin type and goals, but sequence will more or less stay the same

Face Masks + Treatments ❤︎︎

Face Masks -

typically done at home 1-3x/week

clay, gel, mud, cream, liquid

my fav masks at home:

aha + bha liquid mask by the ordinary: a literal overhaul of my pores. it’s refining and helps reduce texture and hyperpigmentation. 1-2 x/week

korean modeling mask: i use this after doing everything in my routine. it’s super cooling and smooths my skin out. the low temp of the mask reduces flushing of my skin and helps the steps in my routine absorb better. 2-3 x/week

Treatments -

done either 1-3x/week and/or exclusively at night

consumer grade Retinols, AHAs, BHAs at high strength

little extra things i like to use to enhance my routine:

gua sha, ice pack, rose quartz roller, however often i choose

Facials ❤︎︎

done every 1-2 months by licensed estheticians

often includes exfoliation and extraction

Classic Facial: cleanse, extract, massage, moisturize

HydraFacials: extracts pores while infusing serums to boost skin’s vitamin and nutrient content

dry, dehydrated skin

Microdermabrasion: microabrasive tool removes outermost, textured, damaged layer of skin using suction to reveal a smooth and refined new layer of skin

sun damaged, aged, textured skin or skin with hyperpigmentation

Chemical Peel: application of medical grade AHA, BHA, Lactic Acid, Fruit Enzymes, or Retinol to peel away top layers of skin over the course of 1-2 weeks

pore refining, brightening, and anti-aging

after care is crucial. skin will be peeling and sensitivity to sun is increased. SPF MUST be used. it’s heavily advised that clients stay home for the first few days.

HydroJelly Facial: facial made of electrolytes, algae, organic white grain oat flour, rice flour, and white willow bark powder. leaving your skin hydrated, plump, and nourished. forms a vacuum-like seal that compresses facial contours.

there are 25 different hydrojelly pro masks for most skin concerns you may have, check here

More Facials ❤︎︎

Contouring Facial: sculpting, tightening, and lifting of facial muscles

LED Facial: uses LED light to soothe inflammation, aiding in acne healing and prevention

Vampire Facial: plumps skin and improves wrinkles by extracting blood, removing its platelets, then either re-injecting it into the skin or applying it topically

Diamond File Facial: finely ground diamonds resurface skin by filing to improve dark spots

Glass Skin Botox: multiple tiny botox injections just below the surface of the skin. alleviate fine lines, redness, texture, and more achieving glass skin

AquaGold Facial: microinjections that combine vampire facial methods, hyaluronic acid, botox, stem cells, antioxidants, vitamins, peptides, etc. improves fine lines, wrinkles, pores, pigmentation, acne scarring, dryness, tone, texture, skin elasticity, and more

cite

Hair:

Hair Care ❤︎︎

Wash Routines:

curly textured: wash and condition every 2-3 weeks, deep condition every 1-2 weeks

straight: wash and condition every 2-3 days, deep condition every 2-3 weeks

Styling ︎❤︎︎

Hair should have a style everyday! At home hairstyling is limitless and really depends on your taste and lifestyle. The everyday woman does her own her once every 1-4 weeks using natural hair products, heat, or other tools.

Professional Stylists:

hair is styled every 1-3 months: uses heat to straighten or curl, extensions to lengthen and add volume, shears to maintain/attain a shape and length

trim ends: every 6-8 weeks

hair color: touched up roughly every 6-8 weeks (depending on how fast your hair is growing and how fast your color will fade)

Silk Press:

after a clarifying wash and deep conditioning, natural hair is straightened using flat iron and/or pressing comb, then usually curled in feathers or pin curls to preserve the style

lasts 3-4 weeks depending on maintenance

preserved by wrapping hair at night, keep hands out of hair, and using a wide toothed comb only

can be further styled with different kind of rollers, or with pin curls

Braids:

afrocentric hairstyles typically done to protect hair while maintaining beauty

lasts 3-8 weeks

styles include knotless braids, faux locs, stitch braids, french braids, etc

Extensions:

hair added to natural hair to enhance length or volume

can be done at home with patience and proper materials

sew-in extensions: (my personal fav) 1-2 months

your natural hair gets braided down flush to your scalp and the bundles are sewn on by the wefts in a flat pattern typically with a section of hair left out to cover the wefts $100-600

microlinks: up to 4 months

i-tip extension is added to hair using micropliers, clippers and loop tool. takes far longer than most extension methods but looks the absolute most natural $500-1000

tape-in extensions: up to a year, touch ups every 4-6 weeks

medical grade tape is used to attach extensions to small sections of hair $200-400

clip-in extensions: 3-6 months

extensions are clipped on by the wefts. the hair itself can last up to six months, but it’s not recommended to sleep, shower, or swim with the extensions in $50-100

Natural Styles:

all last roughly 1-2 weeks at most. allowing hair to completely DRY is crucial for these styles. your natural hair can be further changed in styles like buns, puffs, etc once dry

natural hair essentials: scalp oil, leave in conditioner, detangling brush, wide tooth comb, curling cream, styling gel, edge control and edge brush

wash n’ go

wash and detangle, then use leave in conditioner to keep hair moist. oil on the scalp and ends is recommended for growth and healthy ends

bantu knots

a traditionally african style where the hair is cleanly sectioned (usually parted in a cute pattern) and twisted into knots. style can be worn just like this or taken down for curls

braid/twist out

a specific pattern of curls is achieved after hair is twisted or braided with curl preserving products. end result depends on how big your twists or braids are

roller set

hair is sprayed with water and curl cream applied before roller of your choice is added. hair is left to dry usually overnight for springy well formed curls

Brows and Lashes:

Brow Shaping ❤︎︎

in salon or at home

Waxing - every 3 weeks

Threading- every 2-3 weeks

Razor Shaping - weekly

Brow Enhancement ❤︎︎

Tinting - monthly

can be done at home or by pro in the salon

Microblading - every 1-3 years + annual touch ups, exclusively professional work

cosmetic tattooing using a manual tool with nearly invisible hair-like needles to inject pigment in brows to create your desired brow look

Lash Enhancements ❤︎︎

*done exclusively by professionals

Lifts - every 6 weeks

basically a perm for your lashes to curl them semi-permanently for lashes to appear longer

Lash Extensions - new set every 6-8 weeks, fill ins every 2-3 weeks depending on quality and style

false individual strands of lashes glued to natural lashes to create semi-permanent length and/or volume

lash baths: wet lashes and apply a small amount of gentle cleanser or a “lash bath” to lashes. cleanse lashes and eyelids for about 10 seconds. hold a towel under your eye and use a nozzle bottle to flush soap and bacteria from lashes then dry with a disposable lint free towel. finish by brushing your lashes with a spoolie. daily.

Lash Styles:

Classic: one lash on each fan, thin lashes

Volume: fluffier lashes with more lashes on each fan

Hybrid: uses classic and volume lashes to make an alternated look

Russian: volume lashes made with very thin individuals, 5-6 extensions per natural lash, fanned out look

DIY Lash Extensions - lasts about a week (sometimes longer)

lash fragments or individual wisps are glued either under the lashes or on the lash line. KISS Falscara is a product that makes this concept simple and easy

Nails:

all these services can be done at home with the proper materials and KNOWLEDGE

Classic Manicure ❤︎︎

every 1-2 weeks

nail service that consists of soaking hands in warm soapy water then drying them. nails are trimmed, filed, and buffed. cuticles are pushed back before applying nail polish (base coat, color, top coat), then finally cuticle oil is applied.

nails can be enhanced with rhinestones, glitter, or charms and attached with uv gel or nail glue

my fav styles are pink, cream, white, black and any french tip using those colors

Pedicure ❤︎︎

every 2-4 weeks

sister to the classic manicure, but can be upgraded depending on materials. steps are similar to manicure, except feet are scrubbed and exfoliated before feet are washed and dried to apply nail color

regular polish, acrylic, or gel can be used on toenails

Gel or Shellac Mani ❤︎︎

every 2-3 weeks

same process as the classic manicure, but traditional nail polish is replaced with uv base coat, gel or CND Shellac polish, then uv top coat that’s cured in a UV or LED lamp

longer lasting and more strong/3d than classic mani and is typically removed by soaking in acetone

Apres Gel-X Nails ❤︎︎

every 2-3 weeks

my personal fav at home nails using the artme yoko matsuda nails. after doing a classic mani sans polish, you apply a dehydrator and primer to prep nail for gel. then you apply builder gel to your natural nail and cure. then you apply that same builder to the nail extension after etching it using an electric drill or acetone. marry the gel to your nail and cure. then just shape to your liking and top with uv top coat. tutorial here

Acrylic Nails ❤︎︎

every 2-3 weeks, nails are fully grown out after 6 weeks

manicure done with liquid monomer and acrylic powder to build and extend natural nail, then polished with color or just a top coat if desired

Russian Mani ❤︎︎

every 4-5 weeks

essentially a gel manicure, but more invasive. the eponychium is snipped away so polish can be applied more closely and flush to the cuticle. this aids in visuals and longevity

service is seen as risky because the skin is more susceptible to fungal or bacterial infection. this is actually how i do my nails at home.

Body:

Bathing ❤︎︎

2x daily

self explanatory, we all know how to bathe. i have other posts that talk about my shower and bath routines.

use a gentle cleanser then a scented body wash to complement perfume and smell fresh all day.

if needed, you can use body soaps with actives like aha, bha or retinol to exfoliate or treat skin at night

exfoliation - 2-3x/week. using scrubs, loofahs, bath brushes, etc.

Hair Removal ❤︎︎

shaving - 2-3x/week

waxing - every 3-5 weeks

sugaring - monthly

ipl device - a device that uses light therapy to slowly destroy hair follicles and unwanted pigment in skin. i use mine after every 5-6 shaves but i could really use it more often.

Vajacial ❤︎︎

1-2x/month

a “facial” for your lady area

the esthetician will first wax, then cleanse and apply an enzyme exfoliant. then they extract any blackheads or ingrown hairs from the area before applying a soothing mask usually in the jelly form.

Moisture and Hydration ❤︎︎

body cream or lotion - daily right after bathing to hydrate skin

body oil - daily to seal in moisture and protect skin from debris and dryness

masks - weekly to address particular skin concerns

ex. when i was having eczema flare ups on my back, i used a dead sea mud mask every 1-2 weeks to help treat it

done at home or at spa

glycolic, clay, mud, salicylic, etc.

Enhancement Procedures:

the goal is to look younger and balance facial features. all these services are exclusively done by professionals usually in a medspa and are widely considered luxury.

Botox ❤︎︎

every 6-8 months; between brows, smile lines, outer corners of eyes, etc

discourages muscle movement to reduce wrinkles

Lifts ❤︎︎

lasts about 10 years; face, neck, brow, eyelids

skin is lifted to desired look, then excess skin is removed

Fillers ︎❤︎︎

every 6-12 months; under-eye, lips, jawline, wrinkle sites, cheekbones

injects acids (usually naturally occurring) like Hyaluronic Acid and Calcium Hydroxylapatite to add volume to your face

Body Contouring ❤︎︎

every 2-4 months until desired results are achieved

non invasive liposuction to achieve desired physique

CoolSculpting - cryolipolysis freezes fat cells for the body to the metabolize and and remove them

SculpSure - essentially the same as CoolSculpting, but uses heat and laser technology to destroy fat cells

Laser Hair Removal ❤︎︎

every 5-6 weeks; bikini, underarms, legs, arms

touch ups done every 1-2 years

hair growth is inhibited by exposing follicles to light at frequencies that kill them

Building the Regimen 🗒️💕:

when making appointments with your “glam squad” you can stagger your services by week depending on what’s being done. for example you can get your mani and pedi done one week. then your facials, brows and lashes another week.

Things to Keep in Mind 💭💞:

these frequencies won’t be the same for everyone depending on personal wants, budgets, etc. but will most likely land somewhere in the ranges i gave. if you need touch ups or redos any sooner than i mapped out, then the service most likely was of poor quality.

anything done at home may or may not be up to the level of detail and longevity as salon or spa work. if you see yourself doing the majority of your beauty maintenance at home, this can save money but may end up taking more time than professional services. so it’s a give and take.

More Resources:

manage your routines, services and products using a beauty binder

a look at my skincare routine

at home beauty treatments for the summer

my hair care routine at home

pretty on purpose by @shefromhouston

monthly beauty routine by @angeljpg

dream girl routines by me

[nshtn]

[ UV Albert Wesker Uroboros & PG67 HCs ]

These take after the knowledge that PG67 contains hastily-added leech genes. This is full of medical jargon related to virology and genetics. It's hard sci-fi styled!

the neurology is probably capable of being refuted easily, unfortunately- a lot of sert rabbithole research can't be cited because it's... lacking in couth towards how they talk about neurodivergence...

tags: medical:genetic;neurology (hardly);virology;needles (PG67-A/W), cannibalism mention, childhood trauma, body horror, mental decay

Such a far cry from his beginnings... he's truly taken after the man he hates the most.

Unfortunately for Wesker, adding Uroboros in intensely massive quantities to an existing Progenitor-67 infection is a poor choice that makes him spend much of his fight with Chris alternating between pouncing him like a rabid animal and curling like the death throes of a dying spider.

And unfortunately for Chris, Wesker doesn't die when he's left at the volcano to stew in a puddle of himself. Even with the awakened lack of thermophilic qualities as a result of G, there is enough local flora and fauna to keep him alive, albeit in a subdued state.

Physiological:

Uroboros, combined on the initial foundation of Progenitor 67, takes after Progenitor 67's metabolic inefficiency and drives that far higher than it was ever meant to go in an attempt to sow compatibility.

Due to this, Wesker needs a truly ridiculous amount of calories (~6,000 - ~9,000 kcal/d) to remain fully intelligent.

A lesser amount will generally retain him, though he will experience a plethora of negative symptoms related to starvation (~3,500 - ~5,500 kcal/d).

Wesker cannot digest iron bound to salt or any organic chelates except heme (or hemeprotein) as a result of initial Progenitor 67 infection.

Progenitor 67 epigenetically alters his enterocytes. The genes involved with this are the upregulation of HCP1 and the downregulation of DMT1 and, less intensely, Dcytb, and is a result of both Progenitors' own natural leaning and, primarily, the hasty introduction of leech genes when microinjection became available.

This ultimately means that, as time drags on, he begins to find his palate shifts from a lot of power smoothies to meat.

But there is something crucial here: 67% or more of heme iron is lost when you cook meat. That means...

He slowly slips into preferring his meat blue or raw, otherwise he won't be able to properly supplement his need for heme iron.

With the addition of Uroboros, which dethrones and replaces Progenitor, this change persists and couples roughly with his modified caloric needs.

Uroboros; a monster that eats itself continually without end. It physically presents a sign of Wesker's malingering, creeping need to consume biomass.

Patches of necrotizing, hardening skin and flesh form across his arms and legs in uneven patterns.

Scaly, itchy lesions creep along his cheekbones and the sides of his neck like a corrupted skin flush. They make him look draconic and feral.

These are a weaker, useless vestigial presentation of the hardening of skin he undergoes when he's being flash-fried by high temperatures.

One of the scars of Wesker's infection and subsequent mutative transformation are hypermelanotic deposits.

They start strongest at his fingertips and weaken at the base of his shoulders.

They are also strongest in the center of his chest where his macronuclei is present and taper off approaching his shoulders and abdomen.

His face has some of the same tinting where he was burned and developed heat-resistant scales.

Uroboros enhances the strength of many of his bones - worse closer to the surface of his body - by fortifying them with calcium and double-thickening them.

As a feature of the beginning stages of Uroboros' starvation, it will begin to leach calcium out of bones and the deposits it creates when time to intellect loss is ticking down.

When resources are low, the bones will be stripped for the calcium they uniformly contain, causing him to experience an effect similar to calcium gout / pseudoarthritis, malaise, and brittling.

This leaching undoes itself and becomes re-fortifying under the duress of stress hormones like cholecystokinin and epinephrine.

To note, epigenetic changes brought on by Progenitor physiologically are stacked upon inappropriately and randomly by Uroboros like re-patchwork, which leads to a general instability and accidental incorporation of Progenitor's physical defense mechanisms.

This is what ultimately enables him to survive the events of RE5.

Neurological:

Progenitor infection spiraling into his temporal lobes, brain stem, and, minorly, his frontal lobes as years progress are the cause of his irritation and aggression in RE5.

It does this because it has no antimutagenic properties unlike the more developed t-Virus, slowly mutating out of control into a dysfunctional beast as Wesker experiences more and more stress and trauma.

A bit like G in this regard...

His SERT is disrupted by its' presence in the midbrain raphe nuclei along the brain stem.

This causes elevated extracellular serotonin levels initially, followed by receptor downregulation and eventual serotonin deficiency.

The lack of available serotonin leads him to experience, at first, heightened periods of aggression. Later, this becomes mania and even delirium if he forfeits sleep or a PG/67 shot, because...

As time ticks on, his dopamine begins to become dysregulated as well.

This imbalance contributes to mood swings, aggression, and impaired decision-making.

It also leads to a loss of the ability to feel pleasure or joy in things, making him manic and paranoid, taking risks uncharacteristically to feel something, anything.

As Progenitor 67 degrades brain function, particularly areas involved in impulse control and aggression, Wesker experiences the uncontrollable urge to consume.

This leads him to cannibalize interns and people he calculates won't be missed, as well as people who piss him off enough. During this time it does change - and become true - that a misplaced boop! or headpat! might get you killed.

His ego begins to vacillate and strengthen itself in an effort to maintain itself despite his decline. If he can just finish Uroboros, everything will be okay again, he can fix himself...

His brain practically relies on his PG67-A/W dose before he gains Uroboros.

A rapid decline in cognitive and emotional stability when he’s off the dose is present.

It's not unlike sundowning...

You would not want to see his MRIs during this time. They look awful - his brain has lesions and there are parts that are grossly overgrown; there are tiny black specks where Progenitor has gnawed holes in the fabric of him. If he hadn't roped it in, he would probably end up eventually going completely feral from his brain swelling up against the sides of his skull; he'd just become another victim of Cannibal Disease and turn, simply painfully slowly.

Uroboros is not supposed to crawl into the brain. It's supposed to leave it unaffected - but Progenitor having already curdled and spread unchecked into it gives it an opening for opportunistic infection.

It attempts to knit the holes and tamp down overgrown regions, but in doing this, it feeds from a sort of 'genetic template' that restores Wesker's ability to feel and feel greatly. This includes the reactivation (and reanimation) of the greatly disordered regions of his brain responsible for empathy, sleep regulation, attachment, and guilt.

It also cannot perfectly recreate lost tissue or resurrect memories from dead, liquefied tissue, so he retains some of his symptoms, like mood swings.

Rage becomes consuming, hunger becomes voracious, and guilt becomes haunting; he is plagued with an unfortunate (to him) tendency to consider others.

He finds it a prying weakness, but he can no longer tamp it down into nonexistence as he did; he is, essentially, thermally reduced to his Arklay days in behavior. He’s still intelligent and cunning, but he must now wrestle with intense emotional responses that don’t align with his goals at all...

Guilt and empathy are so foreign to him they are nearly out-of-body; he views them clinically and tries to rationalize them away, but his inability becomes the stake that impales him and imparts a malingering sense of conflict.

...and he must take a good, hard, long look at his goals and how far they've diverted from their initial precedence.

... what is he now? What use does he serve in this world - to what master does he heel, clearly dethroned from his position? These questions and more are things he asks himself now.

Is he doomed to roam aimlessly without purpose until he perishes?

[weskie]

hello weskie, you are so cool! here is something i can't stop thinking about! i hope you enjoy!

stars wesker saves someone and they look at him with big round innocent eyes and thank him profusely and he has no idea how to respond because it's giving him a crisis. he backs off really really awkwardly and nods them off and feels... bad for it. bad. he feels... bad.

what? is he going soft? no, of course not, so he shoves it down and continues like he's supposed to. easy. it's nearly automatic, anyways. slap on a smile.

but what was that, anyway?

he goes back to his office later, when the adrenaline has run off, and he is left with a strange empty feeling when he thinks about returning to the lab again under Umbrella and Spencer and Markus' direction. instead of the consuming pleasant numbness, there is a... some deep lack he hasn't felt in so long, since who knows when.

thinking about the last time he felt it makes his brain feel like it's buzzing, so he doesn't scoop it out from the repressed cage it's in.

not yet, anyway. not that there is ever a good time.

the more he thinks about the nice things civilians say to him, the way they look at him, the way they thank him... the feeling of pride he gets when he completes a mission and no life is lost. being thanked and praised and being someone's savior... it makes him feel warm. it makes him feel like he'd got an A on a test, when he'd microinject a cell and the new gene would be accepted...

it's warm, and it glows tiny and steady, and he feels like he's felt this before but he can't place it and he can't trust anyone with it and he must foster it lest it die and leave him feeling that strange emptiness again.

he is being weak, and yet in this weakness he feels like he finally gels and flows like salmon up a river with team alpha, even mingling properly with team bravo. it's beneficial, right?

but he submits some paperwork for umbrella and the crushing weight around him is suffocating, exhausting the flame. unity is strength. never question your authority. compassion is weakness...

compassion is weakness, right?

and then he saves a child.

and the child looks up at him in a defining moment that will never be erased from their psyche as long as they live, the image of the man who saved them a hero they will think of ten years later and wonder how he's doing.

and wesker is struck again with this feeling, but this time it's not just adrenaline pulling his strings loose.

he embraces it. the kid gives him a hug for saving them.

he returns to his office later and sits in his chair and takes his badge out. he stares at it, the expression behind his shades perplexed and confused... and let down... and ashamed, and immiserated by a sudden and intense feeling of emptiness and lack, like a teddy bear missing an eye; incomplete, the tiniest match of the flame of empathy flickering steadily in him because it crossed paths with the desire to succeed and a savior complex.

artificial.

it cannot last, it won't last. wesker has more important things to do; he is temporary. he should get up and cease this pointless–

but wesker sits there and he looks at the cold reflection in that badge. he looks at the lie of a man whose sole seed of truth is planted in the lifesaving actions he takes for others that umbrella would have no qualms killing for their goals.

umbrella would have no qualms killing him for their goals, either.

chris is thrumming on his guitar; wesker can hear the gentle pluck of chords, clumsy and fumbling, self-taught and learning on their own accord, not forced or coerced.

and for what feels like the very first time the thought has a genuine and concerning amount of feeling to it, wesker wonders what it would be like if he could run away from umbrella... if he could leave... what it would be like to learn what you want when you want to, eat what you want when you want to eat it, dream and fulfill yourself.

have a sense of self instead of a sense of cohesion within a hive that will die to serve.

ARE YOU TRYING TO KILL MEEEEEEEEEEEEEEEEEEEEEEEEEEEEE

This is so tender and devastating all at once. The idea of Wesker slowly but surely falling into the realization that his life could be more, that there is more than what he was raised into at all of those boarding schools, that his immense talent can be used for good… but knowing defecting could and likely would cost him his livelihood if not his life altogether.  I wonder if he ever thought about it. I imagine he would’ve at some point.  Defection was already an idea in his head, clearly, when Umbrella operations started going tits up.  But to do so to pursue a life in which he is a hero– a real hero, not just for subterfuge– is just *chef’s kiss*. I LOVE the idea of an AU where s.t.a.r.s. wesker was truly good, which might be heavy influence from that good wesker au fic i shared a while back, but i do think it would be so interesting to see. especially considering how it would change his relationships with the series' protagonists

[manie-sans-delire-x]

"To address this issue, we applied both ex vivo and in vivo approaches to rats in which fear memory had been consolidated. A unique form of depotentiation reversed conditioning-induced potentiation at thalamic input synapses onto the LA (T-LA synapses) ex vivo. Extinction returned the enhanced T-LA synaptic efficacy observed in conditioned rats to baseline and occluded the depotentiation. Consistently, extinction reversed conditioning-induced enhancement of surface expression of AMPAR subunits in LA synaptosomal preparations. A GluR2-derived peptide that blocks regulated AMPAR endocytosis inhibited depotentiation, and microinjection of a cell-permeable form of the peptide into the LA attenuated extinction."

Me: ...yeah I'm too stupid for this one.

[hearth-fucker]

At work we make our own microinjection needles out of glass capillary tubes. You wake up this beautiful clunky machine which costs around $10,500 for some reason.

Then you carefully and awkwardly line up a tube into the two clamps on opposite sides, while holding the sliders together with your pinkies. Secure the tube into the clamps and, oh oops it wasn't secure. Ok line it up and tighten it again. Ok. Lower the screen so you don't damage your eyes from the white hot metal and press Pull.

The machine heats the glass and pulls the two sides apart until the tube splits in two, creating two needles sharp enough to pierce a cell membrane without damaging it. You can use these to inject 0.000,000,5ml or 0.000,001ml of liquid into an embryo. You cannot see the tip with the naked eye. The tip is so thin it bends a bit if you press on it. It will break if you look at it wrong. Now very very carefully loosen the clamps and remove your needle without damaging the ultra-sharp incredibly fragile tip. And place it into your very scientific holder: a petri dish with modeling clay in it.

Having the needles be the same size is not necessary, but I like when I line it up just right so they're exactly even. It's harder than it looks! I think I did my best job yet today.

[alivewellnessclinics]

Skin boosters, also referred to as microinjections or skin hydration operations, are non-invasive cosmetic procedures made to refresh and improve the appearance of the skin. Small amounts of specific materials are injected into the skin during these procedures to enhance its moisture, flexibility, and smoothness.

[glowskinlaser]

Face Mesotherapy: Benefits and Side Effects

In the ever-evolving world of skincare, Face Mesotherapy has emerged as a revolutionary treatment for achieving radiant, youthful skin. This non-invasive cosmetic procedure has gained popularity for addressing a wide range of skin concerns, from pigmentation to fine lines. If you're curious about this trending treatment, let’s explore its benefits, potential side effects, and essential details, including mesotherapy for face cost in India.

What is Face Mesotherapy?

Face Mesotherapy, often referred to as Meso treatment for the face, involves the injection of vitamins, enzymes, hormones, and plant extracts into the middle layer of the skin (mesoderm). These microinjections are tailored to address specific skin concerns such as hydration, pigmentation, and signs of ageing. Unlike invasive procedures, Mesotherapy offers a natural boost, rejuvenating the skin from within.

Benefits of Face Mesotherapy

Here are some potential benefits of Face Mesotherapy:

1. Improves Skin Hydration

The microinjections deliver hyaluronic acid and vitamins directly into the skin layers, providing intense hydration. This makes the skin appear plumper and more radiant.

2. Reduces Pigmentation

Mesotherapy for face pigmentation is highly effective in targeting dark spots and uneven skin tone. The procedure works by reducing melanin production and promoting skin regeneration.

3. Boosts Collagen Production

The treatment stimulates the production of collagen and elastin, essential proteins for maintaining skin elasticity and firmness.

4. Minimizes Fine Lines and Wrinkles

By improving skin texture and boosting collagen, Face Mesotherapy visibly reduces fine lines and wrinkles.

5. Non-Invasive and Quick Recovery

Unlike surgical treatments, Face Mesotherapy is minimally invasive with little to no downtime, making it a convenient choice for busy individuals.

Read More ...

[theestheticclinics]

Hair Mesotherapy in India: A Breakthrough for Hair Loss Treatment

Hair loss can be a significant concern, affecting self-confidence and leading people to search for effective solutions. One such advanced treatment is Hair Mesotherapy. In recent years, this procedure has gained considerable popularity in India due to its promising results and non-surgical approach. For individuals looking to restore their hair growth with minimal downtime, Hair Mesotherapy offers a unique option that's both effective and accessible.

In this blog, we will dive into what Hair Mesotherapy is, how it works, and why seeking out the best cosmetologists and top dermatologists in India can help you achieve the best results.

 What is Hair Mesotherapy?

Hair Mesotherapy is a non-invasive, therapeutic procedure designed to deliver active ingredients directly to the scalp. It involves a series of microinjections containing nutrients, vitamins, amino acids, and enzymes tailored to promote hair regrowth and restore scalp health. Unlike oral supplements or topical treatments that may not fully penetrate the scalp, Mesotherapy deposits these nutrients directly where they’re most needed.

---

 How Does Hair Mesotherapy Work?

1. Assessment by the Specialist: Initially, the dermatologist or cosmetologist assesses your hair type, scalp condition, and hair loss pattern. This helps in customizing the Mesotherapy blend for your specific needs.

2. Application of Injections: During the procedure, tiny injections are administered to the scalp. The goal is to stimulate blood flow, increase collagen production, and encourage the hair follicles to grow stronger and healthier.

3. Boosted Nutrient Absorption: The nutrients delivered directly to the hair roots help in reversing miniaturization of the hair follicle, thus improving hair thickness and density.

4. Minimally Invasive with Minimal Downtime: Mesotherapy is usually quick and causes minimal discomfort, with most patients returning to normal activities immediately after the treatment.

---

 Benefits of Hair Mesotherapy in India

1. Non-Surgical and Minimal Downtime: This treatment doesn’t involve surgery, so there’s no need for extended downtime or recovery.

2. Tailored for Indian Hair and Scalp Needs: Many top dermatologists in India specialize in creating Mesotherapy blends suited to Indian hair textures and environmental factors, making the treatment more effective.

3. Increases Blood Circulation to Hair Follicles: Improved circulation means better nutrient absorption, resulting in a noticeable improvement in hair health over time.

4. Safe and Effective: When performed by qualified dermatologists or cosmetologists, Hair Mesotherapy is generally safe with few side effects.

5. Boosts Hair Density and Thickness: After several sessions, many patients experience an increase in hair density and improved thickness, which are key indicators of healthy hair growth.

---

 Finding the Best Cosmetologist in India for Hair Mesotherapy

India boasts a vast pool of skilled dermatologists and cosmetologists, especially in cities like Mumbai, Delhi, Bangalore, and Chennai, where dermatology clinics are known for using the latest hair restoration technologies.

When searching for the best cosmetologist in India, consider factors such as:

- Experience with Hair Mesotherapy: The specialist should have significant experience in administering Mesotherapy for hair and be well-versed in customizing treatments for different hair types.

- State-of-the-Art Clinics: Opt for clinics with high standards of hygiene, safety, and the latest Mesotherapy equipment.

- Client Testimonials: Positive client feedback and case studies on successful treatments are a good indicator of a reputable clinic.

Choosing a Top Dermatologist in India

Top dermatologists in India are known for their expertise in various hair loss treatments, including Hair Mesotherapy. They can provide a holistic treatment plan that not only focuses on Mesotherapy but may also include additional therapies, such as PRP (Platelet-Rich Plasma) therapy, low-level laser therapy, or other advanced techniques based on individual needs.

Some of the Top Dermatologists in India who specialize in hair restoration and Mesotherapy typically work out of leading dermatology clinics and hospitals. Checking qualifications, certifications, and reviews can help you make an informed choice.

[driftwooddestiel]

hi are any of my followers biology experts or decently knowledgeable in biology in some way perchance… i need to explain step by step how the gene editing process occurred in this ⬇️ research like on a molecular level + also how the gene was extracted from the human as well and tee bee haych . i have no idea. i have scoured the internet for an explanation of how microinjection works for gene editing on a molecular scale and i have found #nothing n also i cant find anything explaining how it worked specifically in this experiments case either 💔

(text is from here) (the research in question is Erwin Wagner and Uli Rüther’s 1984-1991 research into the Fos oncogene in transgenic mice btw)

anyway if any of you know any resources for where i can find out more abt microinjection or would be able to explain it in simpler terms i will be eternally grateful 🙏

[avellinaaesthetics]

How Can Mesotherapy Boost Your Confidence?

Confidence is often tied to how we perceive ourselves, particularly when it comes to our appearance. Feeling good about how we look can significantly enhance our self-esteem and overall confidence. Mesotherapy, a non-surgical cosmetic treatment, has become increasingly popular for those seeking to rejuvenate their appearance without invasive procedures. If you’re in the Philadelphia area, Mesotherapy Philadelphia could be your key to achieving a youthful and vibrant look, helping you feel more confident in your skin.

What is Mesotherapy?

Mesotherapy is a minimally invasive treatment that involves injecting a cocktail of vitamins, enzymes, hormones, and plant extracts into the skin. These microinjections target the middle layer of the skin, addressing a variety of skin concerns such as fat accumulation, cellulite, hair loss, and signs of aging. The goal of Mesotherapy is to nourish and rejuvenate the skin, improve circulation, and reduce inflammation, leading to a more youthful and radiant appearance.

How Mesotherapy Enhances Your Appearance

One of the primary reasons people choose Mesotherapy is its ability to target specific skin issues. Whether you're dealing with stubborn fat deposits, cellulite, or sagging skin, Mesotherapy can be customized to address your unique concerns.

Skin Rejuvenation: Over time, the skin can lose its elasticity and youthful glow. Mesotherapy can help restore your skin's natural radiance by stimulating collagen and elastin production. This leads to firmer, smoother skin that looks and feels rejuvenated.

Fat Reduction: Mesotherapy can also aid in body contouring by breaking down stubborn fat deposits in areas such as the abdomen, thighs, and arms. This can result in a slimmer, more toned appearance, which can significantly boost your confidence.

Hair Regrowth: For those struggling with hair loss, Mesotherapy can be a game-changer. The treatment can stimulate hair follicles, promoting hair regrowth and thicker, fuller hair.

The Psychological Benefits of Mesotherapy

The physical changes brought about by Mesotherapy can have a profound impact on your mental and emotional well-being. When you feel good about your appearance, it often translates into greater confidence in social, professional, and personal interactions.

Increased Self-Esteem: Improved skin texture, reduced fat, and rejuvenated hair can make you feel more attractive and self-assured. This can lead to a more positive outlook on life and a willingness to engage more actively in social situations.

Enhanced Professional Confidence: A refreshed appearance can also boost your confidence in the workplace. Whether it’s feeling more comfortable during presentations or simply exuding confidence in daily interactions, Mesotherapy can help you present the best version of yourself.

Why Choose Mesotherapy Philadelphia?

If you’re considering Mesotherapy, opting for a reputable provider in your area is crucial. Mesotherapy Philadelphia offers tailored treatments that cater to your specific needs, ensuring that you receive the best care and achieve optimal results. The experienced professionals in Philadelphia understand the unique skin and aesthetic needs of their clients, making them an excellent choice for those looking to enhance their appearance and boost their confidence.

Conclusion

Mesotherapy is more than just a cosmetic treatment; it’s a confidence booster. By addressing various skin concerns and rejuvenating your appearance, this minimally invasive procedure can help you feel more self-assured and ready to face the world. If you’re in the Philadelphia area and looking to improve your appearance, consider exploring Mesotherapy Philadelphia to unlock a more confident you.Click Here - https://www.magcloud.com/user/avellinaaesthetics

[aesthisave]

Jalupro HMW Skin Booster: The Best Anti-Aging Remedies Available

Novel approaches to better address the indications of aging are emerging as the quest for youthful, glowing skin persists. The Jalupro HMW injection stands out among them as a skincare industry game-changer. This potent skin booster, which is intended to revitalize the skin from the inside out, is gaining popularity due to its amazing effects in addressing fine lines, wrinkles, and laxity of the skin.

Hyaluronic acid and a strong amino acid complex are combined in Jalupro HMW skin booster, a sophisticated skin booster that promotes the formation of collagen, improves skin suppleness, and provides deep hydration. The treatment offers a noticeable increase in hydration and firmness and is specifically designed to address more aged skin issues.

A concentrated amount of hyaluronic acid and amino acids is injected into the dermal layer of the skin via the Jalupro skin boosters. Renowned for its exceptional capacity to hold onto moisture, hyaluronic acid plumps up the skin, diminishing the visibility of wrinkles and fine lines. The amino acids leucine, glycine, lysine, and proline help to build collagen and enhance general skin health, which in turn supports the structure of the skin. Usually, microinjections are used to give this therapy, which enables the active components to deeply permeate the skin. Immediate benefits include increased hydration and elasticity, while long-term advantages include reduced aging symptoms and better skin texture.

High molecular weight hyaluronic acid included in Jalupro HMW provides the skin with intensive hydration, assisting in the restoration of moisture levels and the creation of a plump, youthful look. Jalupro HMW's amino acid complex promotes the synthesis of collagen, which is essential for preserving the firmness and suppleness of skin. Over time, this helps to lessen the visibility of wrinkles and fine lines. Jalupro HMW improves the skin's suppleness with repeated treatments, strengthening its resistance to the effects of aging and environmental harm. Jalupro HMW improves the general structure and condition of the skin from the inside out, giving longer-lasting effects than topical lotions that just give momentary hydration. For those with older skin or those who are noticing indications of aging, such as wrinkles, loss of firmness, and dryness, Lemon Bottle Fat Dissolving Injections are helpful. It's also a great choice for people who want to improve the overall brightness of their skin or stop early indications of aging. This treatment can also be utilized to preserve results after the surgery or to prepare the skin for later cosmetic treatments.

[cytgen]

[Open Access Book] Abstract: Plant genetic engineering as a group of technologies and methods that lets scientists change the DNA of many organisms, including plants, bacteria, and animals, covers such methods as biolistic transformation, microinjection, Agrobacterium-mediated transformation. The monograph includes the information about some aspects of the genetic transformation of plants using Agrobacterium rhizogenes soil bacteria: characteristics of the bacteria, role of Ri-plasmids in horizontal gene transfer in nature, plant – Agrobacterium interaction, effect of rol genes on plant secondary metabolism etc. There is also the data about hairy roots induction, their characteristics, cultivation and using as producers of valuable bioactive compounds.

[yourskinexpert]

Mesotherapy: Rejuvenate Your Skin with Targeted Microinjections

Mesotherapy has gained prominence as a minimally invasive cosmetic procedure designed to rejuvenate and revitalize the skin. This comprehensive guide explores the principles behind mesotherapy, its benefits, applications, procedure details, and how it can effectively address various skin concerns to enhance your overall complexion and confidence.

Understanding Mesotherapy: Mesotherapy involves the microinjection of vitamins, minerals, amino acids, and other active ingredients directly into the mesodermal layer of the skin. This technique aims to nourish and rejuvenate the skin from within, stimulating collagen production, improving circulation, and promoting cellular regeneration.

Benefits of Mesotherapy:

Skin Rejuvenation: Enhances skin tone, texture, and elasticity for a more youthful appearance.

Hydration Boost: Provides deep hydration, making the skin plump and supple.

Reduction of Fine Lines and Wrinkles: Minimizes the appearance of wrinkles and fine lines.

Firming and Tightening: Improves skin firmness and tightens sagging areas.

Even Skin Tone: Diminishes hyperpigmentation, sunspots, and acne scars.

Hair Restoration: Stimulates hair follicles to promote hair growth and combat hair loss.

Indications for Mesotherapy: Mesotherapy is suitable for addressing a variety of cosmetic concerns and conditions, including:

Aging skin

Dehydration and dullness

Acne scars and pigmentation

Cellulite reduction

Hair loss and alopecia

Customized Treatment Formulations: The formulation used in mesotherapy can be customized based on individual skin types, concerns, and treatment goals. The cocktail of ingredients may include vitamins (such as Vitamin C and Vitamin E), minerals, hyaluronic acid, peptides, and plant extracts tailored to address specific skin needs.

The Mesotherapy Procedure:

Consultation: A thorough consultation with a trained healthcare professional assesses your skin condition, medical history, and cosmetic goals.

Preparation: The treatment area is cleansed, and a topical numbing cream may be applied for comfort, depending on the sensitivity of the treatment area.

Microinjections: Using a fine needle or mesotherapy gun, the customized cocktail is injected into the targeted areas of the skin or scalp. The injections are shallow, typically reaching the mesodermal layer just beneath the skin's surface.

Multiple Sessions: Mesotherapy treatments are often performed in a series of sessions spaced several weeks apart to achieve optimal results. The number of sessions required varies based on individual skin condition and desired outcomes.

Post-Treatment Care: Following mesotherapy, it's essential to follow post-care instructions provided by your healthcare provider to optimize results and minimize potential side effects:

Avoid Sun Exposure: Protect treated areas from direct sunlight and apply sunscreen regularly.

Gentle Skincare: Use gentle skincare products and avoid harsh exfoliants or irritants that may compromise skin healing.

Hydration: Maintain skin hydration with a moisturizer recommended by your provider to support the skin's recovery process.

Combination Therapies: Mesotherapy can be combined with other cosmetic procedures to enhance overall results:

Microneedling: Combining mesotherapy with microneedling enhances product absorption and stimulates collagen production for improved skin texture and firmness.

Platelet-Rich Plasma (PRP) Therapy: PRP therapy can be incorporated to further boost collagen production and accelerate healing post-mesotherapy.

Laser Treatments: Depending on specific concerns, laser treatments may complement mesotherapy for skin resurfacing and rejuvenation.

Long-Term Results and Maintenance: The longevity of mesotherapy results varies depending on individual factors such as skin type, age, and lifestyle habits. Maintenance sessions may be recommended periodically to sustain improvements and address ongoing skin concerns effectively.

Safety and Considerations: Mesotherapy is generally considered safe when performed by a qualified healthcare professional using sterile techniques and high-quality ingredients. Potential side effects, such as temporary redness, swelling, or bruising at the injection sites, are typically mild and resolve within a few days.

Choosing a Qualified Provider: When considering mesotherapy, select a reputable healthcare provider or cosmetic dermatologist with experience in administering the treatment. Research their credentials, read patient reviews, and schedule a consultation to discuss your expectations and ensure personalized care.

Conclusion: In conclusion, mesotherapy offers a versatile and effective solution for rejuvenating and enhancing skin health through targeted microinjections of beneficial nutrients and active ingredients. Whether you're seeking to reduce wrinkles, improve skin texture, or address specific skin concerns like acne scars or hair loss, mesotherapy provides a tailored approach to achieving radiant and revitalized skin. Embrace the transformative potential of mesotherapy and discover a renewed complexion that reflects your natural beauty and confidence.

[theestheticclinics]

 Hair Mesotherapy in India: A Breakthrough for Hair Loss Treatment

Hair loss can be a significant concern, affecting self-confidence and leading people to search for effective solutions. One such advanced treatment is Hair Mesotherapy. In recent years, this procedure has gained considerable popularity in India due to its promising results and non-surgical approach. For individuals looking to restore their hair growth with minimal downtime, Hair Mesotherapy offers a unique option that's both effective and accessible.

In this blog, we will dive into what Hair Mesotherapy is, how it works, and why seeking out the best cosmetologists and top dermatologists in India can help you achieve the best results.

 What is Hair Mesotherapy?

Hair Mesotherapy is a non-invasive, therapeutic procedure designed to deliver active ingredients directly to the scalp. It involves a series of microinjections containing nutrients, vitamins, amino acids, and enzymes tailored to promote hair regrowth and restore scalp health. Unlike oral supplements or topical treatments that may not fully penetrate the scalp, Mesotherapy deposits these nutrients directly where they’re most needed.

---

 How Does Hair Mesotherapy Work?

1. Assessment by the Specialist: Initially, the dermatologist or cosmetologist assesses your hair type, scalp condition, and hair loss pattern. This helps in customizing the Mesotherapy blend for your specific needs.

2. Application of Injections: During the procedure, tiny injections are administered to the scalp. The goal is to stimulate blood flow, increase collagen production, and encourage the hair follicles to grow stronger and healthier.

3. Boosted Nutrient Absorption: The nutrients delivered directly to the hair roots help in reversing miniaturization of the hair follicle, thus improving hair thickness and density.

4. Minimally Invasive with Minimal Downtime: Mesotherapy is usually quick and causes minimal discomfort, with most patients returning to normal activities immediately after the treatment.

---

 Benefits of Hair Mesotherapy in India

1. Non-Surgical and Minimal Downtime: This treatment doesn’t involve surgery, so there’s no need for extended downtime or recovery.

2. Tailored for Indian Hair and Scalp Needs: Many top dermatologists in India specialize in creating Mesotherapy blends suited to Indian hair textures and environmental factors, making the treatment more effective.

3. Increases Blood Circulation to Hair Follicles: Improved circulation means better nutrient absorption, resulting in a noticeable improvement in hair health over time.

4. Safe and Effective: When performed by qualified dermatologists or cosmetologists, Hair Mesotherapy is generally safe with few side effects.

5. Boosts Hair Density and Thickness: After several sessions, many patients experience an increase in hair density and improved thickness, which are key indicators of healthy hair growth.

---

 Finding the Best Cosmetologist in India for Hair Mesotherapy

India boasts a vast pool of skilled dermatologists and cosmetologists, especially in cities like Mumbai, Delhi, Bangalore, and Chennai, where dermatology clinics are known for using the latest hair restoration technologies.

When searching for the best cosmetologist in India, consider factors such as:

- Experience with Hair Mesotherapy: The specialist should have significant experience in administering Mesotherapy for hair and be well-versed in customizing treatments for different hair types.

- State-of-the-Art Clinics: Opt for clinics with high standards of hygiene, safety, and the latest Mesotherapy equipment.

- Client Testimonials: Positive client feedback and case studies on successful treatments are a good indicator of a reputable clinic.

Choosing a Top Dermatologist in India

Top dermatologists in India are known for their expertise in various hair loss treatments, including Hair Mesotherapy. They can provide a holistic treatment plan that not only focuses on Mesotherapy but may also include additional therapies, such as PRP (Platelet-Rich Plasma) therapy, low-level laser therapy, or other advanced techniques based on individual needs.

Some of the Top Dermatologists in India who specialize in hair restoration and Mesotherapy typically work out of leading dermatology clinics and hospitals. Checking qualifications, certifications, and reviews can help you make an informed choice.