#martinez y ramirez

[empresa-oscura]

Cambio Parte Final... 28/10/24

La siguiente viñeta ocurre el mismo día del Especial 666 (En realidad 661).

Parte 3.

[egotistival]

hi pals! i'm sun and i'm currently 29 y/o and am looking for new writing partners to interact with on tumblr only! below is my current muse list (though i can and will make up characters for any such plots we come up with), and some descriptions of my characters. if you'd like to plot and write with me, feel free to give this a like, me a follow, and i'll come to you (but only if you're 21+)!

jenna ortega fc. soledad ramirez. she/they. writer of the bestelling series “trailblazer.” think wednesday addams meets jo march from little women. has a big mouth, never stops talking, will voice whatever is going on in their head but means well most of the time. sapphic/queer.

kristen stewart fc. micah chase. she/they. a loser, just can’t seem to get it together but has a heart of gold. also kind of involved in some shady dealings around town with drugs, and appears beaten up a lot of the time but no ones really stuck around long enough to voice their concern for them. sapphic/queer.

melissa barrera. lauren martinez. she/her. is she a bitch, or is she just misunderstood? the ever present question. single survivor of a murder/suicide at the hands of her father, but she's still trudging on despite the horror and trauma. sapphic/queer.

emma d’arcy fc. clay nichols. they/them. activist, scientist, and overall golden retriever whose had a string of heartbreaks and broke hearts behind them. think shane mccutcheon from the l word. queer. 

jeffrey dean morgan fc. cyrus dunn. he/him. shady preacher with an even shadier past? is he really a preacher or is he just smuggling in drugs, guns, and other such things in the church for the local biker gang in town like everyone says? unconfirmed. heterosexual. 

mike faist fc. nathan mccintosh. he/him. an awkward geek whose entirely too horny for his own good, but harmless enough. got a scholarship for track and tennis, now on his way to the olympics for competitive sports. spent his whole life trying to live up to his parents expectations and done nothing else. heterosexual. 

charles melton fc. rafe yoo. he/him. stuck up, mean, and incredibly well-off monetarily, he comes from an old money family in town known for shady dealings. best to stay away from him. closeted pansexual.

[dyns33]

The transfer

A Bruce Wayne x female cop being soulmates. 

I was too tired to reread and check all my English mistakes, sorry ! 

Y/N didn't ask to be transferred to the Gotham City Police Department.

Some of her former colleagues said it must have been a mission, because she was a good cop, talented and with integrity, the kind of cop that Gotham seemed to need. Others said it was a punishment, because she was too good and too honest, scaring some who wanted to get rid of her.

Y/N decided to believe it was fate when she met Bruce Wayne.

After all, it was always fate when two soulmates met.

There had been an attempted break-in at the Wayne Tower, the residents had been able to scare the burglar away, but the housekeeper had been very scared, the butler was just getting out of the hospital, and the owner was someone importantly, so several police officers had been sent to the scene to check that they were no longer at risk.

Y/N didn't know Gotham at all. She hadn't really cared about it, except the crime rate, and the neighborhood she had moved to. She only knew some her new colleagues, especially Jim Gordon and Ramirez.

It was a shock to meet Bruce Wayne. An honor according to Ramirez, who seemed to admire the man from afar.

     "Hello... I'm Agent Y/N Y/L/N.", she introduced herself shyly, looking the man in the eye, as she was taking the statement from Mr. Pennyworth and his boss.

The one she thought was her soulmate looked at her too, before lowering his eyes without saying anything. His butler answered all her questions, then he thanked her for her kindness, before accompanying his master to his room.

Bruce Wayne didn't look at her a second time.

Returning to the station, Y/N tried to persuade herself that he was in shock. It could be difficult to meet his soulmate under such circumstances, and he might need time. Or it wasn't the right Bruce Wayne.

She didn't think about it for a while, especially after meeting the Batman.

It didn't seem to shock many people to see a guy dressed as a giant bat walking around town and fighting crime. Well, some cops wanted to arrest him, but others saw him as an ally.

Jim Gordon was one of those threads. And Jim Gordon was a good cop, so Y/N decided to trust him.

     "He can be a little weird, rude, stubborn and quiet, but he helps us a lot. It's not easy to keep peace and security in this city, and even though he's an outlaw, he doesn't never killed anyone, so..."

     "It still wouldn't be good for everyone to start imitating him."

     "You don't know the Riddler, it's obvious."

     "The what ?"

     "You're new."

Gordon was right, he was silent. Rude. Appearing in shadows, speaking little, with his deep voice. The costume might have been ridiculous, but Y/N could understand that the criminals were afraid of him.

The beginnings were complicated, because the Batman did not trust people easily. Like Bruce Wayne, or so it seemed.

Several times, Y/N tried to communicate with him, under the pretext of the progress of the case, but each time, it was the governess or the butler who answered her. They looked sorry, which didn't help her to know if she had found her soulmate or not.

Her teammate, Martinez, taught her more about the Waynes. About what happened when the family came home from the theater. Y/N hadn't thought to inquire on her own, she found it inappropriate. This allowed her to understand Bruce Wayne a little better, and to decide to give him more time.

During this time, she began to get to know the Bat better.

They were working on cases more and more often. The masked vigilante seemed to gradually accept the presence of the new policewoman, even if he remained a man of few words.

According to Gordon, he had spoken to her more than to anyone since his arrival, more than two years ago.

     "Jim will end up being jealous."

     "Why ? He's still my favorite mustachioed cop."

     "I'll tell him you said that."

     "He won't believe you." said Batman with a smile in his voice, despite his impassive face.

After several months, Y/N ended up taking stock of her situation. Gotham's crime rate remained hopelessly the same despite their best efforts. She was starting to like Batman a lot. And Bruce Wayne still hadn't contacted her.

One day when she felt particularly depressed because of her job, she went to the Wayne Tower, where she was greeted by Alfred. The butler doesn't seem to believe for a second her excuse regarding the investigation, which had long been abandoned for lack of evidence.

He was still nice to her, letting her talk. It was then that Bruce walked down the hall. Their eyes met, he paused for a moment, surprised, but visibly recognizing her, before leaving as quickly as he had appeared. His butler apologized for him. Y/N was then certain of two things that day. Bruce Wayne was her soulmate, and he didn't want her.

It was rare to be rejected. Most of the time, your soulmate would either die or you never had the chance to meet them. But rejection ? Horrible.

However, she had to accept the situation and move on. Y/N always had a goal, her job. And Batman.

It was probably a stupid mistake to get attached to a man she knew nothing about, except his mouth and his voice. That she didn't see more than an hour, from time to time, to talk about crimes. But in her loneliness and despair, he was the only person who brought her some joy.

He wasn't as rude as Gordon had said when she kissed him. It was one evening, after a long case. Y/N was very tired. She wanted to go home and sleep. He had come to collect clues, he had noted that she was not well, and contrary to his habits, he had stayed when he had had what he wanted. Almost shyly, he asked if there was anything he could do. And without thinking, she kissed him.

     "... No. Y/N, no." he said kindly, pushing her away before leaving through the window.

They didn't talk about it again. Y/N tried not to be heartbroken for the second time in less than a year. It was stupid.

She thought she understood why the Bat had done this when she saw him with the thief who disguised herself as a cat. They seemed close. Very close.

It wasn't normally proper to talk about other people's soulmates. Soulmates were a private thing. But after almost a year in this city where justice did not work, after being rejected, having lost sleep, having worked with a vigilante, Y/N didn't care a bit about what was proper or not.

     "Is she your soulmate ?"

     "Who ?"

     "The Cat ?" Y/N asked without looking at him, focused on the last crime scene photos they were studying together.

She felt Batman's gaze on her, that dark, piercing gaze. He said nothing for a long moment, which she interpreted as a confession, and a demand that she not continue talking about it.

     "... No." he eventually admited.

     "No ? I thought so."

     "No."

     "Okay. Sorry."

They continued to work in silence, but she could feel that he wasn't as relaxed as before, not as focused, still staring at her instead of thinking about the series of murders they wanted to solve.

     "Have you met your soulmate ?" She couldn't help but ask.

     "... Maybe."

     "I'm not looking to find out your identity, if that's what you're worried about. I'd be glad if you met them. You deserve some happiness and calm in all this darkness."

This time, he was totally looking at her. Y/N forced herself not to turn around, as if she didn't feel he was staring at her gravely.

     "Afterwards, it doesn't matter if you haven't met them yet. It's easier when you're alone, I guess. And you must be afraid that they won't understand, or that they will in danger."

     "... A bit."

     "Nobody's ever really safe. And if they're your soulmate, they'll understand. It's hard, but they'll understand. Anything can be accepted out of love, like... Like rejection."

It was official, they weren't going to finish this case tonight. Y/N couldn't concentrate at all, trying not to cry thinking about Bruce.

     "Don't reject your soulmate if you meet them, please. It hurts, a lot."

     "... You were rejected ?" he asked, as if he didn't believe it.

     "Yes. But he has his reasons. He's had… a tough life."

     "... Maybe it's not rejection. Maybe he's scared, and he's not good with people."

     "It's a certainty, but I still waited almost a year, I know when I'm not wanted. Sorry, it's late."

Batman didn't try to hold her back. He said nothing about her tears, or the ongoing investigation. Y/N was a little disappointed. Even if he had tried to reassure her, she would have wanted more. That he asked her to stay, that he told her that he loved her, that he went on the window of her apartment while she was preparing tea.

Instead, someone knocked on her door, and it wasn't him.

     "... Mister Wayne ?" she wondered when she saw him in front of her, holding roses.

     "I know it's late. For everything. I wanted to apologize and... Invite you ?"

     "Invite me ? Where ? When ? You don't sound sure ?"

     "... I don't know. I never invited anyone."

Bruce Wayne looked as adorable as he was vulnerable in that moment, lost, as he stared down at her feet as he handed her the flowers, whispering that it was for her. Y/N couldn't do anything but invite him in, since he didn't know how.

     "Your place is small." he noted, surveying her apartment.

     “Thanks.”

     "No, I mean... It's fine."

     "Don't take this the wrong way, but why now ?" she asked without hatred or detour.

     "I... I didn't know if it was a good idea, before. I'm losing everyone. They're hurt. I didn't mean to... But you've been here for a year now. You're a good cop. A good person. I wish... I wish I got to know you better."

She didn't ask him how he knew that, asking him if he wanted something to drink, coffee or tea. He demanded what kind of tea, and when she replied real tea, he muttered that Alfred would love her, which made her laugh.

A car passed in the street. The lighting in the apartment wasn't strong, so Bruce's mouth was brighter than the rest of his face for a moment, a brief moment, during which Y/N froze on his lips. Lips that seemed familiar, like that voice and those dark eyes. She thought back to what he had said about fear.

They looked at each other without moving, Y/N trying to hide what she had just understood, and Bruce seemed to be waiting for her to say it.

     "So...  Tea ?"

     "Coffee, thank you."

     "Sugar ?"

     "No, thanks."

     "Oh. Black. Like the suit. Alright."

She had said that as a test, but mainly to make a joke, and lighten the atmosphere. After all, she could be wrong, she was very tired, and very attracted by her soulmate as by the Bat.

A hand on her shoulder made her turn around as she picked up two cups, and there was no longer any doubt when he kissed her. Y/N had already kissed this man.

Bruce Wayne was Batman. Her soulmate. Who she'd been working with for a year, who she'd had a weird relationship with for months, and who hadn't said anything the whole time.

She could have been upset, but it was hard when he was looking at her with that apologetic, scared puppy look. Not good with people, that's what he had said. It was terribly obvious when she wanted to kiss him again, but his attention was already elsewhere, fixed on the window.

     "... I have to go." he sighed, gently pushing her away. "... Thanks for the coffee."

He added nothing. Batman had never been talkative, there was no reason for Bruce to be much more so. He didn't ask her when they were going to see each other again, he would probably find her the following night at the police station. He didn't give her his number either.

In the sky, the Batsignal lit up the clouds, a message for the criminals, and for him. If Y/N wanted to see him, she already knew how.

Despite everything, she showed up the next morning at the Wayne Tower, welcomed by an Alfred who was too smiling for him not to already know, who offered her tea and homemade buicuits, before going to fetch his master.

     "He is not morning person, but it must be said that he sleeps little." said Alfred, returning to sit beside her.

     "It must not be easy for you."

     "You have no idea, my dear. I hope you can help me."

     "I can try, but he's known to be weird, rude, quiet and stubborn."

     "It is the least we can say !"

     "I knew you weren't supposed to meet." Bruce muttered as he entered the living room. "Don't plot against me."

     "It's not a conspiracy if you know about it."

     "Alfred..."

     "We will talk later." whispered the butler with a mischievous smile. "Master Bruce, don't sigh, come back and eat a bit with Miss Y/L/N !"

Y/N tried not to laugh as Bruce acted like a child. With this new perspective, he sometimes acted like Batman, but he seemed more mature because of the mask, showing no emotion when Jim spoke to him like Alfred.

He came over to her, muttering a shy hello, taking a seat on her right to chew on two blueberries, before letting his hand slide against the chair, one of his fingers touching her hand.

A year ago, Y/N arrived in Gotham, a dark, hopeless city where she didn't know anyone. At that moment, thinking about her job, her co-workers, and her ridiculously adorable soulmate who fought crime at night disguised as a giant bat, she thought she couldn't have asked for a better transfer.

[crucifycorii]

hey look it's kappu jose hernandez lopez ramirez garcia flores de el castillo cabello agua de horchata carillo apaga los frijoles cortes de leon pinche huevon martinez bidi bom bol perez bad bunny benito culo de la cruz aghacate amor santa maria el senal de la cruz de el nombra del padre, y del hijo,y de espiritu santo amen padre nuestro que estas en el cielo santitficado sea tu nombre blanco macia melendez rosas rios la ross patas de culo torres velasco casa cata cato fernandez guzman rubio carlos miguel pablo francisco juan mayo noe fatima chuy jesus cesar felipe javier chavo kurayami

(please tell me you get it, i did not spend 15 minutes typing that for no one to get it)

[depuertoplata-blog]

Pakolé estrena su nuevo tema “La Reina” y causa furor en la gente

Arreglada por Juan Valdés y remontándose a los años 80 la canción se posiciona Con una energía que invita a bailar de inmediato y un ritmo contagioso, fue estrenado el tema “La Reina”, una creación del cantante Elvin Martinez Ramirez (Pakolé) que promete convertirse en el himno de la salsa en esta temporada. “La Reina”, interpretada y compuesta por el talentoso y carismático salsero, es una…

[voguecovers]

• Vogue México y Latinoamérica, September 2024

Vogue Mexico y Latinoamérica celebrates its 25th anniversary with this special cover dedicated to Colombia as a global cultural reference ❜

Colombian model Nazarit Machín, photography by Emmanuel Sanchez Monsalve

❛ styling Ivan Dario Ramirez, head of content Karla Martinez de Salas

25th Anniversary Vogue México y Latinoamérica

[ola-rojita]

Conozca los postulados a rectores del CNE (+Listado)

Los nombre de los 75 postulados y postuladas a rectores y rectoras del Consejo Nacional Electoral (CNE) que pasaron la etapa de evaluación realizada por el Comité de Postulaciones Electorales, fueron dados a conocer por el Comité de Postulaciones Electorales de la Asamblea Nacional (AN).

El Comité informó que de las 75 postulaciones que superaron esta etapa, 47 pertenecen a la sociedad civil, 10 a las universidades y 18 al Poder Ciudadano, cumpliendo así con el artículo 26 de la Ley Orgánica del Poder Electoral.

A continuación el listado

Candidatos postulados por las facultades de Ciencia Jurídicas y Políticas de las Universidades:

5.424.288 HAROLD ELISEO ALBORNOZ TORREALBA 8.789.248 CARMEN ALVAREZ CABEZA 9.363.630 ANGEL ZULEY ANTUNEZ PEREZ 13.748.998 WILSON GOMEZ GUEVARA 4.767.120 ALEJANDRO JOSE UGARTE SPERANDIO

7.726.798 PEDRO ALBERTO ISEA GONZALEZ 7.275.591 JOSE RAMON MUÑOZ MONTILLA 11.469.855 LILIMAR JOSEFINA ROJAS DAVILA 4.793.004 LERMIT JOSE ROSELL PUCHE 12.630.557 MICHELY ALEXANDRA VIVAS CHACON

Candidatos postulados por el Poder Ciudadano:

4.596.507 FRANCISCO GUSTAVO AMONI VELASQUEZ 10.815.608 ODALIS YANETTE ARTEAGA PEÑA 9.683.971 ALFREDO GERMAN BAPTISTA OVIEDO 9.652.930 REINALDO ENRIQUE CARVALLO MACHADO 7.959.098 JULIO ANTONIO DUNO OLIVEROS 11.199.471 MANUEL JOSE ESCAURIZA SANCHEZ 6.730.853 WILLIAM JOSE FERNANDEZ RANGEL 12.061.089 AURA ROSA HERNANDEZ MORENO 6.492.846 CELESTE JOSEFINA LIENDO LIENDO

11.785.927 DOMINGO MEDINA GUTIERREZ 14.316.687 ANTONIO JOSE MENESES RODRIGUEZ 18.094.872 LEONEL ENRIQUE PARICA HERNANDEZ 10.948.762 ESTHELA MARIA RINCONES 17.799.433 EBENEZER DAVID RIVERA BRAZAO 9.640.547 SHEILA YUBIRY ROMERO GONZALEZ 6.836.622 CARMEN ALIDA VIGIL BENCOMO 6.297.704 GUSTAVO ADOLFO VIZCAINO GIL 11.957.784 CARLOS EDUARDO ZAMBRANO GELVES

Postulados por las Organizaciones de la Sociedad:

14.017.686 HELEN DAYANA AGUIAR HERNANDEZ 14.306.972 AMELIA ESTHER ALTER PINO 7.659.795 ELVIS HIDROBO AMOROSO 4.506.504 LEON ANTONIO ARISMENDI ANUEL 11.159.050 ESTEBAN STEVE ARVELO RUIZ 4.077.208 SAUL DE JESUS BERNAL PEÑA 4.248.113 OSCAR BRAULIO BRAVO GUARAMATO 10.886.311 GRISELDA VANITI COLINA HIBIRMA 11.691.429 TANIA DE AMELIO CARDIET 5.962.704 JUAN CARLOS DEL PINO 3.187.497 DAVID DELGADO ITURRIZA 13.339.266 ANA PAULA DINIZ SANTOS 5.217.642 WUILLIAM FERNANDEZ FUENMAYOR 5.524.394 CARMEN LUCRECIA GONZALEZ CORONEL 12.731.271 EUGENIO GONZALEZ MARTINEZ 4.132.092 ALFONSO GRANADILLO MALAVE 17.375.543 JHONNY ALEXIS GUERRERO CASTILLO 12.248.860 GABRIEL GREGORIO GUERRERO GIL 8.967.366 DICHELIS JOSEFINA GUEVARA 1.567.695 JOSE ALONSO GUEVARA GUERRA 7.048.576 JOSE LUIS GUTIERREZ PARRA 3.180.027 LUIS ENRIQUE LANDER LARRALDE 14.533.009 CIRO VLADIMIR LEON 16.288.462 AMANDA CORINA LUCCI ROYE

7.528.966 NOEL YORELBE MABARES 7.761.966 FRANCISCO JOSE MARTINEZ GARCIA 7.950.191 LADYS COROMOTO MEJIAS ROJAS 3.750.465 BERNARDO MENDEZ ACOSTA 3.552.194 CELIZ RAMON MENDOZA 4.771.335 LEONARDO ENRIQUE MORALES POLEO 6.094.547 JOEL GUSTAVO OLOYOLA CARRASQUEL 4.505.818 JOSE ENRIQUE PARRA MAURERA 3.927.576 EURO DE JESUS PARRA MONTIEL 4.323.185 CONRADO RAMON PEREZ BRICEÑO 12.095.154 ANIBAL JOSE PERNIA CONTRERAS 6.560.218 ROBERTO ANTONIO PICON HERRERA 10.719.241 CARLOS ENRIQUE QUINTERO CUEVAS 4.271.137 TULIO ALFONSO RAMIREZ CUICAS 14.143.740 ROSMERY GERALDINE RAMIREZ DIAZ 10.451.000 ROBINSON RIVAS SUAREZ 11.657.235 AQUILINO ANTONIO RODRIGUEZ GARCIA 13.970.262 DENNY ALEXANDER RUIZ FARFAN 12.839.942 YVAN JOSE SALCEDO UZCATEGUI 12.950.777 MAYGRET DEL MILAGRO SANCHEZ BARRERA 6.671.155 JHOVANY SEVILLA GASPAR 13.875.503 JUAN JOSE TORRES LARA 12.014.259 JOE PONCE UZCATEGUI GONZALEZ

Cabe destacar que este miércoles, el vicepresidente del Comité de Postulaciones Electorales, diputado José Gregorio Correa, precisó que la lista con los nombres de los venezolanos seleccionados como elegibles se podrá impugnar durante 6 días, quienes tendrán ese mismo tiempo para hacer los descargos de las objeciones.

El Consejo Nacional Electoral está integrado por cinco (5) miembros, denominados Rectoras o Rectores Electorales, cuyo periodo de ejercicio en sus funciones es de siete (7) años. Son designadas o designados por la Asamblea Nacional con el voto favorable de las dos terceras partes de sus integrantes y podrán ser reelegidas o reelegidos en sus cargos hasta un máximo de dos (2) periodos adicionales, previa evaluación de su gestión por parte de la Asamblea Nacional.

[padremax]

Puedes participar de la Misa de hoy siguiendo este enlace:

Ofrecida por las siguientes intenciones:

~ En Acción de Gracias a Dios, nuestro Padre, por la intercesión:

- del Espíritu Santo, por la Renovación Carismática Católica en Maracaibo.

- del Sagrado corazón de Jesús por una intención especial de la Familia Tulli Durán y por el Cumpleaños de Nelva Rios de Martinez.

- Jesús de la Misericordia por las intenciones y salud de María Isabel Texeira.

- de Nuestra Señora de Coromoto, por los que laboran en el Hospital Coromoto.

- de la Virgen del Rosario.

- Virgen Desatadora de Nudos por las intenciones de Mario Andrés, Víctor Hugo, Yanet Rosa Durán.

- Por las intenciones de: la familia González Parra, la familia Parra Díaz y Marin Farias- Ramirez.

~ Pedimos por la salud y recuperación de:

• enfermos del Covid-19 y por los que trabajan por su sanación.

• Padre Danilo Calderón, Padre Alberto Gutierrez, Hno. Thomas Smith, Flor Navarro y Maria Galindo.

• Jorge Negrón, Rosario Rivera, Antonio Guerrero, Marcolina Quintero, Valentina Paulovich y José Alejandro Delgado Rodríguez.

~ Por los bienhechores de nuestra Parroquia, del Seminario, de la Fundación Cura de Ars y Fundación Comedor Santa Ana.

~ Por el descanso eterno de:

+ Hilda Margarita Carrizo de Morisco. (3° años).

+ Rita Julia Ortega de Borjas.

+ Blanca Josefina Morales Maggiolo de Gill (1º mes).

+ María Eugenia Sánchez.

+ Alfredo Enrique Ule Sánchez.

+ José Gregorio Mogollón González.

+ Pedro Alcalá Rhodolfo.

+ Francisco Jesús Quintero Dajer.

+ Miguel Ovidio Pérez.

+ Doménico Lombardi.

+ Letizia Lombardi.

+ Gerardo Lombardi Bettini.

+ Francisco Lombardi Lombardi.

+ Humberto Martínez Núñez.

+ Elena Molero de Padrón (2/9).

+ Javier Hernán José Verá Urdaneta (3/9).

+ María Josefina Morrel de Morrel (3/9).

+ Maritza Josefina León de Medina (5/9).

+ Antonio José cordero Ball (23/30).

+ Huilan Nelly Maruja Ball Berci (6/15).

+ Nora Montiel de Russo.

+ Giuseppe Russo Graziano.

+ Alexis Raúl Bracho Martínez.

+ Hérmilo Paez Ávila.

+ Carlos Alberto Ortiz Ochoa.

+ Gregorio de la Rivera.

+ Alexandra del Pilar Yánez Quintero.

+ Chichi Quintero.

+ Bernardo Larreal Herrera.

+ Nelson Enrique Sthormes.

+ Luís Marín.

+ Jorge Romero Martínez.

+ Sili Hernández Belloso.

+Animas del purgatorio más necesitadas.

Para anotar intención de misa, escribe por whatsapp o SMS al +58-424-6293617‬. Para transferir ofrenda voluntaria a la cuenta de Max Güerere, C.I. 10.918.893, BOD # 0116-0103-1500-2623-9345.

[dofuuu]

More info on stem cells !

Here is an additional post regarding stem cells that go a little more in-depth to help you understand regenerative medicine a bit more!

The first thing that people think of when someone mentions stem cells are stem cells that originate from human embryos (referred to hESC) which indeed have been used in research as they are able to differentiate (develop) into any cell in the body (they are pluripotent). 

A study in 2018 explored the possibility of hESC-based treatment for patients with diabetes mellitus– more specifically, to differentiate those hESC to pancreatic cells that will form functional beta cells capable of releasing insulin in response to elevated blood glucose. The results of this study have been favourable and show great promise for potential treatment of diabetes patients.

However, there has been restricted use of hESC across many countries due to the involvement of human embryos, which has raised moral concerns.

As mentioned in the previous post, there are various different types of stem cells that can be used in stem cell research, so hESC use is not the only option available; another such type of stem cell is the induced pluripotent stem cell (referred to as iPSC).

Like hESC, iPSC are pluripotent and able to differentiate to various cells in the body. But unlike hESC, iPSC are not naturally found in the body as-is, rather, they’re a result of the reprogramming of somatic (already-differentiated, from the body) cells to increase expression of specific stem cell-related genes.  Everyone’s own cells are different, so different people may respond differently when given the same drugs, which is why the use of iPSC for testing proves to be an invaluable tool for diagnostics and drug testing. Additionally, because iPSC can come from the patient’s own body, there is no risk for immune rejection following a transplantation with these reprogrammed cells.

To give an example as to how iPSC have been involved in research, a group of researchers used iPSC by differentiating them to become microglial cells (which are found in your brain and spinal cord) to help examine how these cells are like in various neurological diseases such as Alzheimer’s disease.

Even so, potential stem cell therapies using hESC and iPSC are not completely without challenges. Cell reprogramming for iPSC generation is not very efficient, as the process of dedifferentiating cells proves difficult, alongside the elevated expression of genes that may lead to excessive cell division. Furthermore, due to their pluripotent nature, these stem cells also may run the risk of tumour formation after being transplanted into a patient; despite this, there have been ongoing research studies to improve overcome these issues. 

For instance, with respect to reprogramming for iPSC, one research group focused on finding small molecular compounds to replace the initial method of using proteins (which are called transcription factors) to induce iPSC generation, with the goal of both shortening the amount of time needed to convert the cells to stem cells as well as reducing the likelihood of tumour formation.

In summation, our understanding of diseases and how they may be treated continue to improve as great advances have been made in stem cell research and consequently, regenerative medicine. 

Thank you so much for reading!

References:

Volarevic, V., Markovic, B.S., Gazdic, M., Volarevic, A., Jovicic, N., Arsenijevic, N., Armstrong, L., Djonov, V., Lak, M., & Stojkovic, M. (2018). Ethical and Safety Issues of Stem Cell-Based Therapy. International Journal of Medical Sciences, 15(1). 36-45. doi: 10.7150/ijms.21666

Robert, T., De Mesmaker, I., Stangé, G.M. Suenens, K.G., Ling, Z., Kroon, E.J., & Pipeleers, D.G. (2018). Functional Beta Cell Mass from Device-Encapsulated hESC-Derived Pancreatic Endoderm Achieving Metabolic Control. Stem Cell Reports, 10(3). 739-750. doi:10.1016/j.stemcr.2018.01.040

Porter, L. (2020). ESCs and the Future [PPT slides]. Retrieved from https://blackboard.uwindsor.ca/bbcswebdav/pid-1209433-dt-content-rid-13841676_1/xid-13841676_1

Abud, E.M., Ramirez, R.N., Martinez, E.S, Healy, L.M., Nguyen, H.H., Newman, S.A., Yeromin, A.V., Scarfone, V.M., Marsh, S.E., Fimbres, C., Caraway, C.A., Fote, G.M., Madany, A.M., Agrawal, A., Kayed, R., Gylys, K.H., Calahan, M.D., Cummings, B.J., Antel, J.P., Mortazavi, A., Carson, M.J., Poon, & W.W., Blurton-Jones, M. (2017). iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron, 94(2). 278-293. doi:10.1016/j.neuron.2017.03.042

Chen, G., Guo, Y., Li, C., & Wan, X. (2020). Small Molecules that Promote Self-Renewal of Stem Cells and Somatic Cell Reprogramming. Stem Cell Reviews and Reports. Advanced online publication. doi:10.1007/s12015-020-09965-w

[kereshq]

Mw, por favorcito

femeninos.- natalia dyer, zoey deutch, vanessa morgan, victoria pedretti, lucy boynton , emma mackey, aimee lou wood, diana silvers, mina el hammani, danna paola, maría pedraza, alice pagani, zendaya, barbie ferreira, alexa demie, sydney sweney, cierra ramirez, maia mitchell, kristine froseth, natasha liu bordizzo, kathryn newton, olivia dejonge, gideon adlon, camila mendes, madelaine petsch, florence pugh, lily rose deep, hailee steinfeld, sofia carson, saoirse ronan, danielle rose russell, kaylee bryant, las chicas de blackpink.

masculinos.- rome flynn, fionn whitehead, dylan sprayberry, ansel elgort, charlie rowe, tommy martinez, chance perdomo, ross lynch, gavin leatherwood, charles melton,  jacob elordi, angus cloud, tom holland, shawn mendes, miguel bernardeau, arón piper, itzan escamilla, álvaro rico, miguel herrán, jaime lorente, jorge lópez, xavier serrano, lorenzo zurzolo, joe kery, charlie heaton, dacre montgomery, noah centineo, froy gutierrez, reece king, keith powers, ross buttler, justice smith, keiynan lonsdale, los chicos de bts, de outerbanks, elliot fletcher, jaden smith, luka sabbat, jordan fisher, jack mulhern, alberto rosende, nick robinson, thomas doherty, gregg sulkin, asa butterfield, timothée chalamet, 

cualquier faceclaim es bienvenido, amor. siempre y cuando sea mayor de edad, no sea alguien fallecido, o alguien que no desee ser roleado. y por eventos recientes, creemos que es prudente no utilizar los rostros de los miembros de 5sos.

DICKINSON.

[empresa-oscura]

Cambio Parte 3... 21/10/24

La siguiente viñeta ocurre el mismo día del Especial 666 (En realidad 661).

Parte 2.

[musepirations]

                                                     ╰ ✦ ⥽ PLOTTING CALL ⥼ ✦ ╮

hi angels !! so, my exams/assignments are ending next week ( for a little bit, of course ) which means i will get some more time to be online from next week. and there is nothing i want more than some cute/fluffy/angsty/etc... things to write out because i feel like i haven’t been truly engaged or taken by roleplay in a while -- i’d love for that to change again. if you prefer to roleplay in group over doing 1x1s, you can find me in @eclatanthq ( where i still have two open connections, for my roles pixie and davina, give them a look if you’re potentially interested !! ) and i might be interested in starting a simple, oc town group to go back to the 2014 roleplay roots... stay tuned for that. but for now, i would love to maybe do some 1x1s !! below the cut, i will be listening what i would die for right now, so if you’re interested in any of it, please don’t hesitate to HIT ME UP !! xoxo

➮ WANTED OPPOSITES

harry styles ( give me all the harry’s to roleplay against, pretty please with a c h e r r y on top -- you get it ?? anyways, harry, always !! )

manny montana ( i have never gotten the privilege to roleplaying against a manny and after seeing good girls and graceland, i’d literally kill ( with kindness o f  c o u r s e ) for a manny opposite )

tommy martinez

noah centineo

charlie hunnam

daniel sunjata

chris hemsworth

tom hardy

tom holland

chadwick boseman

chance perdomo

can yaman

matthew daddario

sam heughan

danielle campbell

inbar lavi

blake lively

lana condor

lily collins

lalisa manoban

halston sage

literally any woman ( except for t-swift, selena gomez, amber heard, holland roden etc... )

➮ WANTED FACES

danielle campbell

zoey deutch

inbar lavi

leighton meester

antoinette robertson

margot robbie

olivia holt

cierra ramirez

madelaine petsch

samantha logan

ana de armas

dianna agron

shay mitchell

laura harrier

tom ellis

manny montana

harry styles

noah centineo

shawn mendes

chris evans

matthew daddario

avan jogia

michael b. jordan

gavin leatherwood

➮ WANTED PLOTS

literally anything in THIS TAG, or whatever you have in your tag ?? i’m more than open to just throwing ideas around, based on characters or whatever -- lets just brainstorm, do what we both want to do etc... don’t hesitate to message me, please !! 

[blogstayfit101love-blog]

Campeonato de España (Badajoz) FEFF (resultados)

Campeonato de España de resultados (Badajoz) FEFF biomarcadores , evento celebrado los días 14 y 15 de octubre en IFEBA en Badajoz.

Campeonato de España (Badajoz) FEFF 2017 Master Classic culturismo resultados

1. Manuel Sanchez Mira (Comunidad Valenciana) (5)

2. Antonio Hernandez Parra (Murcia) (8)

3. Juan Francisco Rojas García (Comunidad de Madrid) (2)

4. Pedro Fuentes Crespo (Castilla y León) (6)

5. Plumas redondas de Vicenç (Katalonia) (7)

6. Ramón Fallas Berrocal (Katalonia) (3)

. Jordi Valls (Katalonien) (4)

Bodyfitness Senior hasta 158 cm

1. Anabel Da Cruz Valenzuela (Katalonia) (98)

2. Meire Alves Da Silva (Katalonia) (102)

3. Rocío Ibáñez García (La Rioja) (88)

4 Sarah-Ashleigh Baker (Andalucía) (93)

5. Lucia Castillo Sanchez (Comunidad de Madrid) (109)

6. Maria Isabel Fernandez Fernandez (Galicia) (119)

. Alba Brox García (Comunidad de Madrid) (110)

Bodyfitness senior exige 163 cm

1. Elena Eulalia Ordoñez Mendez (Extremadura) (104)

2. Zaira Serrano Alama (Andalucía) (92)

3. Anna Ferrer Flos (Cataluña) (89)

4. Iune Gonzalez Ojembarrena (Cataluña) (118)

5. Rafaela Silva (Cataluña) (115)

6. Isabel Mendiola Torrón (Madrid en su totalidad) (99)

. Sara Rodríguez Berza (Galicia) (96)

. Montserrat Celaya Ramírez (Katalonia) (100)

. Cristina Rodriguez Olmos (Comunidad Valenciana) (103)

. Nuria Sans Roselló (Katalonien) (105)

. BegoñGarcia Villarraco (Comunidad Valenciana) (107)

. Luisa Gil Serrato (Baleares) (108)

. Mirian Ramos Caceres (Andalucía) (118)

Bodyfitness Senior hasta 168 cm

1. Marisa Lobato Gutierrez (Andalusia) (114)

2. Marina Navas Campaña (Comunidad de Madrid) (120)

3. Laura Benasques Borau (Katalonia) (122)

4. Mihaela Loredana Caiuteanu (Canarias) (116)

5. Pino Leon Yamila (Canarias) (94)

6. Guadalupe Quiles Robles (Comunidad Valenciana) (95)

. Silvia Tambo Arizcure (Comunidad de Madrid) (97)

Bodyfitness Senior plus 168 cm

1. Raquel Arranz Fernandez (Galicia) (117)

2. Sjoukje Van Der Heide (Andalucía) (112)

3. Helena Castro Roman (Andalucía) (90)

4. Montserrat Celaya Ramírez (Katalonia) (101)

5. Veronica Martin Martin (Comunidad de Madrid) (91)

6. Soraya Alvarez Peñuela (Asturia) (106)

. Sonia Trapero Burgos (La Rioja) (121)

Campeón absoluto de bodyfitness

Raquel Arranz Fernandez (Galicia) (117)

Bikini Fitness Junior

1. Elena Maria López Baena (Andalucía) (12)

2. Rocio Araujo Carrasco (Asturias) (20)

3. Sonia Bierge De Juan (Cataluña) (18)

4. Rosa Lopez Alamo (Andalucía) (11)

5. Tatiana Mompean Guillen (Comunidad Valenciana) (21)

6. Georgina Rivas Vilanova (Katalonien) (15)

. Ana Amante Gregorio (Murcia) (9)

. Paola García CéSpedes (Andalusia) (10)

. Raquel Frias Martinez (Cataluña) (13)

. Estefania Robles Rodriguez (Comunidad Valenciana) (14)

. Pilar Fernandez Jaen (Extremadura) (16)

. belén Gutiérrez Martín (Castilla y León) (17)

. Raquel Gonzalez Adan (Canarias) (19)

Bikini Fitness Master hasta 163 cm

1. Sonia Rodriguez Martin (Cataluña) (131)

2. Rebeca Mena Serrano (Cataluña) (129)

3. Kamila Pardamcova (Andalucía) (140)

4. Rocio Pedrero Rivera (Andalusia) (128)

5. Tamara Iglesias Elvira (Comunidad de Madrid) (139)

6. Gloria Borregales Simancas (Comunidad de Madrid) (127)

. Karina Balladares De Larramendi (Galicia) (130)

. Irene Carrasco Rojas (Euskadi) (133)

. Maria Del Rosario Guillen (Murcia) (136)

Bikini Fitness Master plus 163 cm

1. Valeria Noel Britos (Cataluña) (132)

2. Sandra Cortés Román (Cataluña) (138)

3. Rocio Feria González (Andalucía) (135)

4. Sarahy Gonzalez Hernandez (Canarias) (137)

5. Raquel Heras Bohajar (Comunidad Valenciana) (143)

6. Sonia Gomez Baeza (Galicia) (125)

. Marta Guijaro Rojas (Comunidad de Madrid) (126)

. Vanesa Carrera Pérez (Euskadi) (134)

. Irene Ibañez Martin (Comunidad de Madrid) (141)

. Marzo Verónica Vilas Faggiotto (Andalucía) (142)

. Virginia Borrego Fernandez (Andalucía) (144)

El maestro absoluto de Bikini Fitness Master

Valeria Noel Britos (Cataluña) (132)

padre físico masculino hasta 170 cm

1. Alejandro Cerrejón Torrano (Murcia) (33)

2. Julián Francisco Marín Celdran (Murcia) (53)

3. Juan Guillermo Ballesteros Cebrian (Andalusia) (73)

4. Michael Anthony Bosca Sanchez (Cataluña) (36)

5. Jonathan Alvarez Rodriguez (Asturias) (30)

6. Joel Nogal Fernández (Comunidad de Madrid) (74)

. Jose Antonio Afonso Luis (Canarias) (23)

. Aitor Alfonso Vivas (Euskadi) (25)

. Antonio Fernando Abellon Jimenez (Murcia) (37)

. Jose Antonio Chacon Guerrero (Andalusia) (39)

. Kiko Antonov (Comunidad Valenciana) (46)

. Angel Pintor Cencerrado (Comunidad Valenciana) (51)

. Jose Antonio Gomez Moreno (Andalucía) (66)

. Yassine Tamaste (Murcia) (67)

. Miguel Angel Salinas Fernández (Comunidad de Madrid) (71)

Javier Domínguez Fernández (Comunidad de Madrid) (32)

Italo Alberto Solano Montilla (Comunidad Valenciana) (50)

Gedeon Martinez Vilchez (Comunidad de Madrid) (75)

Guillermo Rodriguez Izquierdo (Extremadura) (84)

Valeriano Gallardo Mulero (Extremadura) (87)

padre físico masculino hasta 178 cm

1. Cristian Triano Cantero (Andalucía) (65)

2. Dario Fernandez Verdes (Asturias) (22)

3. Dario Javier Teran Burgos (Murcia) (58)

4. Aitor Alfonso Vivas (Euskadi) (52)

5. David Fillol Perez (Andalucía) (28)

6. Manuel Casado Gil (Valencian yhteiso) (86)

. Victor Martinez Hita (Cataluña) (29)

. Adrian Herranz Sanz (Comunidad de Madrid) (35)

. Marcos Iglesias García (Comunidad Valenciana) (40)

. Miguel Jimenez Rodriguez (Euskadi) (41)

. Javier Torrijos Mediavilla (Comunidad de Madrid) (47)

. Jorge Santiago Gallego (Andalusia) (68)

. Sergio Gaitan Baez (Andalucía) (70)

. Salvador Aguilar Martin (Andalucía) (78)

. Cristian Ledesma Ruiz (Comunidad de Madrid) (82)

Salvador Macias Lucena (Andalusia) (34)

Pedro Gallego Rubiales (Andalusia) (48)

Eric Vives Celaya (Katalonia) (63)

Ivan Castesana Figueroa (Galicia) (64)

Arturo Martínez Serrano (Castilla La Mancha) (72)

Jose Antonio Jimenez Martin (Andalucía) (79)

Juan Pedro Moya Esteban (Murcia) (80)

Adrian Madolell Berrocal (Melilla) (81)

padre físico masculino más 178 cm

1. Henry Johnson (Castilla y León) (76)

2. Antonio Moreno Llado (Baleares) (31)

3. Norberto Benitez Martin (Andalucía) (54)

4. David Meis Martin (Comunidad de Madrid) (62)

5. Cesar Varela Garate (Galicia) (56)

6. Marc Alvero Díez (Katalonia) (83)

. Jorge Peña (Comunidad Valenciana) (27)

. Kevin Molla Vadillo (Comunidad Valenciana) (38)

. Miguel Angel Lluch Blazquez (Comunidad Valenciana) (42)

. Alberto Gil Burgos (Comunidad de Madrid) (43)

. Daniel Gonzalez Ruiz (Canarias) (44)

. Eneko Baz Valle (País Vasco) (45)

. Fermín Díaz Rodríguez (Comunidad de Madrid) (49)

. Carlos García-Soldado Martos (Comunidad de Madrid) (59)

. Josue Santos Santiago (Extremadura) (69)

Vicente Vacas Ibañez (Andalucía) (24)

Xabier Ramirez De La Piscina Viudez (Euskadi) (26)

Xavier Castillejos Figueras (Cataluña) (55)

Sergio Curado Gonzalez Andaucia (57)

Jorge Antonio Fernandez Sanchez (Andalucía) (85)

El maestro absoluto de la física masculina.

Henry Johnson (Castilla y León) (76) Parejas de culturismo 1. Carlos Blanco y Raquel Arranz (Galicia) (124) 2. José Yuste Andreu y Vanesa Ruiz (Comunidad Valenciana) (123) Culturismo sénior, hasta 70 kg 1. José Miguel López Vázquez (Galicia) (161) 2. Sebastián Matias Ruedas (Cataluña) (151) 3. Raúl Pérez Soro (Comunidad Valenciana) (216)

4. Carlos Ferreira Poudevida (Katalonia) (152)

5. Gonzalo Izquierdo Conejero (Extremadura) (171)

6. Jose Luis Perez Martin (Andalucía) (170)

. Jose Javier Rosique Barba (Murcia) (164)

. Pedro Javier Gutierrez Ortuño (Murcia) (202)

Culturismo más viejo hasta 75 kg.

1. Adrian Diaz Montero (Comunidad de Madrid) (172)

2. Enrique Cárdenas Almeda (Andalucía) (155)

3. Maximiliano Rodríguez Jiménez (Castilla La Mancha) (220)

4. Kevin Orellana González (Cataluña) (173)

5. Boris Corcuera (Cataluña) (175)

6. José Francisco Tornel Gómez (Comunidad Valenciana) (147)

. Antonio Balmont Llopis (Comunidad Valenciana) (148)

. Ángel Cañón Diez (Castilla y León) (162)

. Santos Crispin Cruz Troya (Cataluña) (163)

. Jose Miguel Galindo Hornero (Katalonia) (169)

. Aaron Chedey Martin Martell (Canarias) (174)

. Marcos Gustavo Schanz (Baleares) (178)

. David López García (Cataluña) (179)

. Jose Teodoro Amador Campiñez (Valencian yhteiso) (180)

. Xavier Jaume Fernandez (Baleares) (184)

. Alejandro Lorenzo Contreras (Andalucía) (194)

Culturismo más antiguo, hasta 80 kg.

1. Jorge Fernandez Dominguez (Andalucía) (177)

2. Francisco Javier Osés Pastori (Andalucía) (157)

3. Bartolome Perales Barragan (Euskadi) (176)

4. Cesar Francisco Borja Molla (Comunidad Valenciana) (145)

5. Marco Grado Estruch (Katalonien) (153)

6. David Saborido Arca (Galicia) (182)

. Osmer Osvaldo Flores Márquez (Castilla y León) (150)

. Alonso Hernandez Ortiz (Extremadura) (158)

. Gregorio San Jose Garrido (Comunidad de Madrid) (160)

. Jose Yuste Andreu (Comunidad Valenciana) (165)

. David Sanchez Pintado (Comunidad de Madrid) (167)

. Antonio Bautista Pérez (Cataluña) (168)

. Antonio José González Garrido (Andalusia) (181)

. Julián Conde Sorga (Galicia) (183)

Culturismo más viejo hasta 85 kg.

1. Alberto Alonso Martínez (Katalonia) (185)

2. Jose Luis Ortiz Ortiz (Extremadura) (191)

3. Edward Alejandro Lopez Buitrago (Melilla) (189)

4 Guillermo Rodríguez López (Andalucía) (192)

5. Jesús Sancho Alcalde (Kastilia La Mancha) (223)

6. Emilio Jose Bueno Alcaraz (Andalucía) (186)

. Juan De Dios Marmol Oliva (Murcia) (146)

. Jacob Torreblanca Coloma (Comunidad Valenciana) (154)

. David Fernandez Fernandez (Andalucía) (156)

. Planelles alemanes Manzanaro (Comunidad Valenciana) (159)

. Juan Antonio Crespo Grillo (Katalonia) (187)

. Sergio Roldán Fernández (Cataluña) (190)

. Antonio Jose Navarrete Ruiz (Andalucía) (193)

. Oscar Ferriols Lloret (Comunidad Valenciana) (204)

. Bernardo Busquets Sastre (Baleares) (214)

. Jesus Ortega Huelamo (Comunidad de Madrid) (222) Culturismo antiguo, hasta 90 kg 1. Roberto Martínez Pizana (Comunidad Valenciana) (201)

2. Carlos Ube Tena (Cataluña) (188)

3. David Cámara La Fuente (Kastilia La Mancha) (218)

4. Vicente Olombrada Ferragud (Comunidad Valenciana) (199)

5. Jesús Gallego Martín (Comunidad de Madrid) (217)

6. Tiago Jorge Sousa Marques (Extremadura) (215)

. Andres Garcia Diaz (Andalucía) (60)

. Manuel Hernandez Puertas (Andalusia) (196)

. Cristian Forga Gascon (Cataluña) (197)

. Manuel Ignacio Moreno Madero (Andalusia) (198)

. Jose Manuel Herrrero Clemente (Andalucía) (213)

. Rafael De Pedro Redondo (Katalonia) (221)

. Daryl Ernesto Orozco Sanchez (Comunidad de Madrid) (224)

Culturismo más viejo más 90 kg

1. Gregory Henri Luc Bellot (Comunidad Valenciana) (219)

2. Ousmane Bathyli (Cataluña) (205)

3. Carlos Blanco Sanjurjo (Galicia) (166)

4. Roberto Castellanos Perez (Extremadura) (206)

5. Antonio Valero Tuinenburg (Comunidad Valenciana) (217)

6. Jose Antonio Guerra Triviño (Katalonia) (203)

. Juan De Dios Romero Nadal (Andalusia) (200)

. Pedro Redin Azcona (Euskadi) (207)

. Sebastián Lago Quintáns (Castilla y León) (208)

. Ian Marc Guitart Erikson (Cataluña) (209)

. Guillermo Bermudo Alcaide (Katalonia) (210)

. Javier Cantalejo Homs (La Rioja) (211)

Un maestro absoluto del culturismo

Gregory Henri Luc Bellot (Comunidad Valenciana) (219)

[laura-1309-blog1]

Tengo casi dos meses  aquí en el Estado de San Luis Potosí  en mi regreso  he estado buscando a viejos amigos y me encuentro  con la sorpresa  que mi estimado  amigo  VICTOR  OSVALDO RAMIREZ MARTINEZ  #SKULLRAMIREZ esta desaparecido desde desde hace casi 3 meses no se si a sus familiares y amigos se les haga muy común no saber de el que niegan cualquier información,  pero en estos momentos hay situaciones  que no sabemos que este pasando  en realidad, si Tu Victor Osvaldo Ramirez Martinez  lees esto solo has saber que estas bien o si alguien sabe sólo  den una señal, de lo contrario  ayúdenme  a compartir  y crear conciencia que hay AMIGOS PREOCUPADOS POR TU BIENESTAR . Sus datos son los siguientes. Nombre: Víctor Osvaldo Ramirez Martinez Fecha de nacimiento : 27/09/1981 Nacido:San Luis Potosí Se le vio la última vez:  Circuito Oriente Colonia Maya mil Por favor cualquier información este es mi número de WhatsApp 4851028007 Laura Piña Hernández https://www.instagram.com/p/B_tDeLzF8dv/?igshid=1do6r60oqwy6h