#diabetes medicine in siddha

[naturalhomeremediesco]

How to Enjoy Jamun for Optimal Health

Jamun, or black plum, is a powerhouse of antioxidants! Packed with vitamins C and A, it supports immune health, aids digestion, and regulates blood sugar levels. Enjoy this delicious fruit for a tasty boost to your well-being!

Jamun, also known as black plum or Indian blackberry, is a tropical fruit native to the Indian subcontinent. Revered for its rich flavor and vibrant deep purple color, jamun is not only a delightful addition to various dishes but also a powerhouse of nutrition. Packed with essential vitamins, minerals, and antioxidants, this seasonal fruit is particularly celebrated for its health benefits,…

[brainlabsai]

mayura gastric problems ayurvedic hospital in hyderabad

Gastric issues refer to a range of conditions that affect the digestive system, including bloating, gas, constipation, diarrhea, indigestion, acid reflux, and abdominal pain. Ayurveda is a traditional Indian system of medicine that uses natural remedies and lifestyle modifications to treat various health conditions, including gastric issues

[chennaitop10]

Siddha Hospitals: Reviving Ancient Healing Traditions

Siddha medicine, one of the oldest systems of traditional medicine, has its roots deeply embedded in Tamil Nadu, India. With its origins tracing back thousands of years, Siddha medicine is known for its holistic approach to healing, focusing on the balance between the body, mind, and spirit. Siddha hospitals play a crucial role in preserving and promoting this ancient healing tradition.Discover the top 10 Siddha hospitals in Chennai offering holistic treatments rooted in ancient wisdom. Experience expert care with trusted Siddha practitioners for your health and well-being.

What is Siddha Medicine?

Siddha medicine is based on the principles of balancing the three humors—Vatha, Pitta, and Kapha—which govern the physical and mental well-being of an individual. The system incorporates natural remedies, lifestyle modifications, and spiritual practices to treat ailments and maintain overall health. The Siddha system also emphasizes prevention, encouraging individuals to live in harmony with nature.

Services Offered by Siddha Hospitals

Modern Siddha hospitals blend traditional knowledge with contemporary healthcare facilities, making them accessible and effective for today’s patients. Common services include:

Consultations: Expert Siddha practitioners assess patients holistically, considering physical, mental, and emotional factors.

Herbal Treatments: The use of herbal medicines, oils, and powders is central to curing various chronic and acute illnesses.

Therapies: Siddha hospitals offer therapies like Varmam (energy point manipulation), yoga, and meditation.

Detoxification: Specialized detox programs cleanse the body, helping restore natural balance.

Specialized Treatments: Chronic illnesses like arthritis, diabetes, skin diseases, and respiratory disorders are managed effectively through Siddha medicine.

Benefits of Siddha Medicine

Natural Healing: Siddha treatments are derived from natural resources like herbs, minerals, and animal products, ensuring minimal side effects.

Holistic Approach: The emphasis on mind-body harmony leads to overall well-being.

Chronic Disease Management: Siddha medicine has proven to be effective in managing and curing chronic conditions.

Preventive Care: It educates individuals on leading healthier lifestyles to prevent diseases.

Popular Siddha Hospitals in India

Several renowned Siddha hospitals are leading the way in reviving this ancient system:

Government Siddha Medical College & Hospital, Chennai: A leading institution offering treatment and education in Siddha medicine.

Santhigiri Siddha Hospital, Tamil Nadu: Known for its state-of-the-art facilities and experienced practitioners.

SKM Siddha Ayurveda Hospital, Erode: Offering integrated treatments combining Siddha and Ayurveda.

Arogya Siddha Hospital, Coimbatore: Specializes in herbal treatments and wellness therapies.

The Future of Siddha Medicine

With the increasing demand for natural and holistic treatments, Siddha medicine is gaining global recognition. Efforts are being made to document ancient texts, research new applications, and integrate Siddha practices with modern healthcare systems. Siddha hospitals are at the forefront of this revival, ensuring the knowledge is preserved and passed down to future generations.

Conclusion

Siddha hospitals are not just healthcare facilities; they are guardians of an ancient tradition. By combining traditional wisdom with modern practices, these hospitals are creating a bridge between the past and the future. For those seeking a natural, holistic approach to health and well-being, Siddha medicine offers a timeless solution.Explore renowned Siddha hospitals in Chennai for traditional healing and natural remedies. Get expert care from skilled practitioners for holistic wellness.

[dhakshin-ayurveda]

Emblica Officinalis Dried Fruit Extract: A Nutritional and Therapeutic Powerhouse

Introduction

Emblica officinalis is a plant scientifically known as amla, Indian gooseberry the plant has been employed in traditional systems of medicine for quite some time now. Its dried fruit extract is a rich source of active fractions containing bioactive compounds of substantial health value. Foremost among Research herbs in Ayurveda, amla, labeled as Rasayana, draws much attention and investigation both scientific and otherwise. It also reveals more than thirty research on the elements present in the amla extract, its uses for treatment and its mode of operation.

Historical And Traditional Uses

 Ayurvedic Medicine 

Amla is a primary herb used in Ayurveda that is referenced in classic texts, Charaka Samhita and Sushruta Samhita, pp. It is said to possess a refrigerant and deobstruent property with equal affinity for V, P and K. Amla is used in Chyawanprash which is a very widely used in the Ayurvedic form of medicine to boost one’s immunity and energy levels. 

Global Traditional Medicine 

According to the Unani system of medicine amla is used to strengthen the liver and cure digestive problems. In Siddha, it is used to cure diabetes, respiratory diseases and for the treatment of the aging population

2. Chemical Composition of Emblica Officinalis Dried Fruit Extract

Vitamin C (Ascorbic Acid)

Amla is also considered to be one among the richest fruits that contain vitamin C which is again an antioxidant immunising agent.

2.Polyphenols

oEmblicanin A and B: Tannins that recycle vitamin C with continued antioxidant properties. 

oGallic Acid and Ellagic Acid: Highly effective antioxidants capable of eradicating freely moving radicals and exhibiting anti inflammatory and anticancer activities .

3.Flavonoids

It contains Quercetin and Kaempferol, which have cardio and neuronal protective properties.

4.Alkaloids and Lignans

Alkaloids such as phyllaantine help in hepatoprotective effects, while lignans have anticancer effects.

5.Minerals

oRich in calcium phosphorus and iron preliminary to promoting bone health and metabolism.

3.Health Benefits of Emblica Officinalis Dried Fruit Extract

a)Antioxidant Powerhouse

Amla is a potent antioxidant, neutralizing free radicals that cause oxidative stress. 

 • Mechanism:Polyphenols like emblicanin A and B regenerate ascorbic acid, creating a long-lasting antioxidant effect .

  • Evidence:Studies confirm that amla extract reduces oxidative stress markers in conditions like diabetes and cardiovascular disease

b) Immune System Booster

Amla’s immunomodulatory properties enhance the body’s natural defense mechanisms. 

ActivationofImmuneCells: Amla stimulates macrophages, NK cells, and lymphocytes, critical for combating infections .

 Antimicrobial Effects: Inhibits pathogens like E. coli, S. aureus, and Candida albicans .

c) Anti-inflammatory and Anti-aging Effects

Amla helps to decrease inflammation and fights aging from the level of the cell.

Anti-inflammatory Action: Since amla suppresses formations of NF-κB and COX-2, the component has a protective effect from chronic inflammatory conditions such as arthritis and metabolic disorder . 

Skin Health: Amla strengthens the skin’s collagen layer, helps wrinkles .

d)Cardiovascular Health

Amla extract has been shown to show beneficial effects on the heart by correcting the lipid profiles and preventing oxidative stress. 

• Cholesterol Management: Reduces the levels of LDL cholesterol and triglycerides while improving HDL cholesterol .

 • BloodPressure: This makes it easy to control pressures within blood vessels due to its constituent of Nitric oxide that encourages the widening of the blood vessel.

e)Digestive and Liver Health 

Amla helps to enhance the health of the intestines and even helps the liver to guard against toxic compounds.

 •Digestive Support: Stimulates the production of bile, which sets and plays an emancipating role in the digestion of fats and absorption of nutrients.

 •Hepatoprotection: Amla contains two primary groups of biologically active compounds called alkaloids and polyphenols that work on the liver cells by preventing damage caused by oxidants and swelling. 

f)Anti-diabetic Effects

 Amla extract is good in maintaining healthy blood sugar levels and enhances the body’s interaction with insulin. 

Mechanism: Flavonoids as ellagic acid show moderate effect on alpha-amylase and alpha- glucosidase thereby reducing carbohydrate intake .

Clinical Evidence: Supplementation for a longer term also reduces concentration of fasting blood glucose and HbA1c

g)Anti-cancer Potential 

New research introduces the use of amla in tackling cancer disease since it has antioxidants that helps in shrinking the cancer cells. 

•Apoptosis Induction: Gallic acid and ellagic acid induce apoptosis in cancer cells . 

Angiogenesis Inhibition: Amla inhibits VEGF so that in turn no new blood vessels can form on the tumor.

4. Mechanisms of Action

Antioxidant Activity: Inactivates free radicals such as ROS and stimulates the body’s own antioxidant enzymes inclusive of SOD and catalase .

Immune Modulation: Improve cytokine synthesis and key immune cell activation .

3.Enzyme Inhibition: Polyphenols decrease the activity of enzymes that digest carbohydrates, as well as enzymes that promote inflammation including alpha-amylase- and COX-2. 

4.Cellular Protection: Remedies oxidized DNA and cell membrane through preventing oxidative reactions.

5.Modern Applications of Emblica Officinalis Dried Fruit Extract •Nutraceuticals: Present in multivitamin with immunity and nutraceuticals, antioxidant, and anti aging products. 

Functional Foods: Conducted in cessation related beverages like teas, gummies, and health bars for nutrition.

Cosmetics: Used in lotions and solutions as a skin care product to fight skin aging. 

Herbal Formulations: An important part of herbal formulations such as Chyawanprash and Triphala. 

6. Safety and Recommended Dosage Safety Profile

Safety Profile

Amla extract is toxin-free and is considered safe when taken in the right proportions, and is also devoid of dangerous side effects.

Dosage 

Usually the dose is between 250 mg to 1,000 mg daily of the standard extract which comprises 20 per cent to 30 per cent tannin. See a doctor or health care worker for specific advice.

 Conclusion 

Emblica officinalis dried fruit extract is a natural nutritional supplement with extensive health benefits. From enhancing the body’s defense mechanism to control chronic illnesses, its efficacy is justified by both tradition and research. Used in a number of nutraceuticals and functional foods, it is indicative of the importance of the concept of holistic health practices.

[pankajbanerjee-official]

AYUSH MEDICINES: Magic or Logic (2024)

Magic is the use of supernatural forces to create effects that defy natural laws and evoke a sense of wonder.

Magic is an effective use of laws of physics to create illusion and virtual reality to make people believe things that they can't imagine under normal circumstances with common sense.

Many a times due to scientific shortcuts and lack of wisdom or vested intentions, traditional practices are termed Magics.

AYUSH medicines, which include Ayurveda, Yoga, Naturopathy, Unani, Siddha, and Homeopathy, are sometimes colloquially referred to as "magic remedies" because of their holistic approach to health, centuries-old practices, and the perceived "miraculous" benefits they offer in managing various ailments by the abusers and consortium of evidence based practitioners. This label is often rooted due to popular perception rather than clinical evidence, reflecting how traditional healing systems are seen to work gently and naturally, sometimes achieving results where conventional treatments may fall short. And surprise at most times evoke doubts.

Hence, the term "magic remedies" can be misleading, as AYUSH therapies are grounded in specific philosophical and medicinal principles, and not in supernatural effects. The label sometimes diminishes the scientific foundations and the extensive yet unfortunately undocumented traditional knowledge that backs these systems. The Indian government, through the Ministry of AYUSH, has been promoting scientific research and clinical validation to establish the efficacy of AYUSH therapies more formally.

The term "magic remedies" has not been historically attributed to Ayurvedic medicines by any specific person. However, the phrase gained legal significance in India through the Drugs and Magic Remedies (Objectionable Advertisements) Act, 1954, which regulates advertisements claiming miraculous cures in Allopathic, Ayurvedic, and other traditional medicines to prevent misleading claims. The act used "magic remedies" broadly to address exaggerated claims rather than any official or scientific designation of Ayurvedic or traditional medicines as magical.

Few examples of companies that faced action for violating the Drugs and Magic Remedies (Objectionable Advertisements) Act in India:

(2016): Company XX was scrutinized for promoting certain products with exaggerated health claims, including remedies for diabetes, blood pressure, and joint pain. The Advertising Standards Council of India (ASCI) flagged multiple ads for making unsubstantiated claims, leading to corrective actions.

YY Ayurveda (2021): YY faced legal issues when its advertisements claimed their products could effectively "cure" serious conditions like diabetes and hypertension. The claims were deemed misleading as they lacked scientific validation.

ZZZZ: Known for producing traditional Ayurvedic products, ZZZZ received warnings for advertisements that overstated the effects of some formulations, including claims to cure serious illnesses, violating the Magic Remedies Act.

These cases emphasize the importance of responsible advertising and adherence to regulations in the AYUSH sector.

Let's understand what specific issues that require tightening of administration.

(2020): AAAA promoted Proxozeen as a COVID-19 "cure" without sufficient scientific evidence. The claim received widespread criticism, leading to government intervention. Authorities required AAAA to revise its labeling and advertise Proxozeen as an immunity booster instead of a cure for COVID-19.

YY Ayurveda Diabetes Cure Claim: YY Ayurveda advertised certain products as a permanent cure for diabetes, without clinical support for the claim. This led the ASCI to issue a warning, highlighting that such ads could mislead patients into abandoning conventional treatment for diabetes management.

ZZZZ's Anti-Asthma and Cancer Treatment Claims: ZZZZ faced scrutiny for ads claiming that certain products could treat asthma and even cancer effectively. These advertisements lacked clinical evidence and were flagged for making unverified promises about serious health conditions.

These examples underscore the importance of evidence-based products and communication with adherence to introductory regulatory standards in licensing AYUSH products responsibly.

To avoid being tagged as "magic remedies," companies manufacturing AYUSH products should:

Follow Scientific Validation: Invest in clinical trials and scientific research to validate claims with evidence-based outcomes at product introduction.

Comply with Regulations: Adhere to guidelines set by regulatory authorities like the Drugs and Magic Remedies (Objectionable Advertisements) Act, 1954 and the Ministry of AYUSH, avoiding exaggerated or misleading health claims.

Use Transparent Marketing: Focus on educational marketing that clearly explains the benefits based on evidence based traditional knowledge and scientific support rather than promising "miraculous" cures.

Label Responsibly: Ensure product labels and advertisements are accurate, emphasizing well-supported benefits and safe usage without overstated promises.

Engage in Certification: Obtain quality certifications (like WHO standard GMP or ISO) to build credibility and consumer trust, emphasizing safety and efficacy.

By maintaining these standards, both AYUSH and its companies can promote products responsibly and enhance public trust in traditional medicine.

There's no shortcuts to success. Ayurvedic companies should not be excused for proper documentation and compliance at product introduction in local markets under Ministry of AYUSH. The companies continue to struggle with the followings even in 2024:

Traditional Knowledge vs. Modern Documentation: Many Ayurvedic formulations are based on traditional recipes without modern validation processes, which may not align with the rigorous documentation standards required for modern healthcare. This results in gaps when substantiating claims with scientific evidence, as traditional practices focus more on holistic benefits than specific, measurable outcomes.

Cost and Complexity of Research: Conducting clinical trials, maintaining strict quality control, and complying with documentation standards require significant investment. Many smaller companies lack the resources to conduct such trials, leading them to bypass extensive documentation to reduce costs. Govt. should come up with a policy to support if the innovation is unique as per committee validation.

Limited Regulatory Oversight: Although the Ministry of AYUSH has set regulatory guidelines (scope for improvement remains and that's an ongoing process), the enforcement of these standards is inconsistent across states. Inspections and audits are often irregular, and smaller companies can sometimes operate without comprehensive scrutiny. This lack of strict oversight allows some companies to launch products with minimal compliance (this needs a strict stoppage).

Lack of Penalties and Follow-Through: The penalties for non-compliance are often not substantial enough to deter companies from cutting corners. The Ministry of AYUSH and local regulators sometimes lack the resources or coordination to impose effective penalties, especially in cases of misleading advertisements or low-quality production practices.

To strengthen the system, the Ministry of AYUSH will come up with stricter compliance checks and enforcements, increase penalties for violations, and improve collaboration with state-level authorities for more consistent oversight. Additionally, providing grand subsidies or incentives for scientific research on AYUSH formulations could encourage companies to invest in proper documentation and clinical validation.

Global Red Flags is a regular phenomenon by multiple countries across developed world makes manufacturers decategorize products to expand global presence and that's mostly because the complex regulation of traditional medicines across different countries. That is largely due to multiple factors, with no single party solely to blame.

Historical and Cultural Variability: Each country has its own historical and cultural ties to traditional medicine, such as Ayurveda in India, Traditional Chinese Medicine in China, and Native American herbal practices in the U.S. These unique roots have led countries to develop independent regulatory standards based on local needs and beliefs rather than a unified global standard.

Lack of Global Regulatory Authority: The World Health Organization (WHO) provides guidance but lacks the power to enforce regulations globally. As a result, countries are free to adapt WHO recommendations to suit their own regulatory frameworks and health policies, leading to varied levels of regulation.

Scientific and Evidence Gaps: The limited availability of scientific research and clinical validation for many traditional medicines makes it difficult to develop global standards. Since evidence-based criteria differ across countries, regulators often rely on local practices and existing cultural acceptance when setting standards, which contributes to inconsistency.

Political and Economic Interests: National interests often shape health regulations. Countries with strong traditional medicine markets may have looser regulatory frameworks to encourage domestic industry growth, while others impose stricter standards to protect their markets or healthcare systems. This variation reflects different political and economic agendas regarding traditional medicine.

Lack of Collaborative Mechanisms: Despite some efforts to promote international collaboration on traditional medicine, limited cross-border regulatory cooperation makes it challenging to achieve harmonized standards. Diverse legal and health priorities make consensus difficult, especially without formal frameworks for international regulatory alignment.

The varied regulation of traditional medicine is a result of historical, cultural, scientific, political, and organizational factors. Greater collaboration between countries, increased funding for scientific research, and a stronger role for organizations like WHO could help address these inconsistencies.

The World Health Organization (WHO) has made strides in acknowledging and integrating traditional medicine through initiatives like its Traditional Medicine Strategy (2014-2023) and the establishment of the Global Centre for Traditional Medicine in Jamnagar, Gujarat, India. However, WHO still faces challenges in effectively evaluating and standardizing traditional medicine globally:

Lack of Standardized Frameworks: Traditional medicine systems vary widely across cultures, with unique methodologies, terminologies, and diagnostic approaches. WHO lacks a unified framework to evaluate the safety, efficacy, and quality of these diverse practices, making it challenging to apply consistent global standards.

Limited Clinical Research and Evidence: Many traditional practices lack large-scale clinical trials or high-quality scientific evidence due to resource constraints or reliance on oral traditions. WHO's focus on evidence-based approaches makes it difficult to assess practices with minimal or culturally distinct documentation.

Funding and Resources: The WHO’s resources are often prioritized for urgent global health issues, leaving limited funding for establishing an independent, robust wing dedicated solely to traditional medicine. This financial limitation affects the organization’s ability to research, standardize, and provide guidance on traditional medicines globally.

Regulatory Diversity and Legal Constraints: Different countries have varied regulatory requirements for traditional medicine. This diversity, combined with WHO's non-regulatory role, limits its ability to enforce guidelines, as WHO can only provide recommendations that countries may or may not adopt.

Balancing Cultural Sensitivity with Scientific Rigor: WHO must respect cultural practices while promoting scientifically validated health practices. Striking this balance is complex and can slow down efforts to create a dedicated wing with rigorous evaluation standards.

To address these gaps, WHO could benefit from increased funding, partnerships with research institutions, and collaboration with regulatory bodies worldwide. This would enhance its capacity to create a comprehensive framework for evaluating traditional medicine systems and foster global acceptance through evidence-based validation.

The Magic Remedy needs to be taken care of with Evidence based Documented approach at origin to ensure all innovations in the field of healthcare doesn't face Tragic Localised Fate.

[namayush]

How AYUSH is Shaping a Healthier Future for India | Traditional Wellness

The ancient medicinal stream and the natural therapies have seen a country boast of its holistic healing. Rising interest in healthy and preventive practice has highlighted AYUSH in short-a combination of Ayurveda, Yoga, and Naturopathy, Unani, Siddha, and Homeopathy- as the focal point to establish a better future for the country. Besides safeguarding India’s traditional knowledge, AYUSH is also offering practical solutions to modern health challenges through the use of natural medicine and wellness and preventive care. In this blog, we look at how AYUSH is seeding a healthier future for India.

What is AYUSH and Why is It Important for India?

AYUSH as a way of life would primarily constitute an indicator of ancient healing systems that are based on the natural, organic, and global treatment systems. Each component of AYUSH addresses various health concerns:

Ayurveda: The art and science of medicine that focuses on the integration and equilibrium of body, mind and spirit by the use of herbs, diet and lifestyles.

Yoga & Naturopathy: This system emphasizes the practice of physical, mental, and spiritual health through yoga postures, meditation, and nature-based therapies.

Unani: It is a treatment system based on the Hippocratic school of ancient Greek medicine; its treatment relies upon attaining equilibrium or balance in the body’s humors while using plant-based treatments.

Siddha: This originated in South India and makes use of a combination of herbs, minerals, and animal products for treatment.

Homeopathy: Uses minute doses of natural substances to stimulate the body’s healing responses.

The importance of AYUSH lies in its focus on holistic health, prevention, and the preservation of India’s traditional medical wisdom. With modern medicine often addressing symptoms rather than root causes, AYUSH’s preventive and natural approach is gaining significant appeal.

How AYUSH Supports Preventive Healthcare

Prevention of disease starts; AYUSH promotes healthy lifestyles, lifestyle habits, diet management, and stress management prevent diseases. The various disciplines of AYUSH in preventive healthcare activities are as follows:

Ayurveda emphasizes daily routines known as dinacharya and seasonal routines known as ritucharya to attain body equilibrium. Yogas can boost the strength of the body and enhance mental clearness, which are pretty useful in helping manage stress-a great key to most health issues. The philosophy of naturopathy supports natural therapies such as hydrotherapy and fasting, where detoxification takes place in the body. Thus, AYUSH advocates lifestyle interventions, preventive activities, and healthy habits, which are environment-friendly and can be followed in the day-to-day lifestyle and decrease healthcare burden.

AYUSH as a Solution for Chronic Illnesses

In India, there is an alarming increase in chronic conditions like diabetes, hypertension, and arthritis, which can be attributed to the modern day lifestyle and stress. In such cases, AYUSH has effective management options available using natural means without the or less use of medication. Ayurveda uses various herbal medications including ashwagandha and turmeric that are administered to reduce inflammation apart from improving the immune system of an individual.

Homeopathy tries to manage the symptoms of chronic diseases by stimulating natural healing responses in the body.

The Siddha and Unani systems, too, are involved with specific formulations and treatment options for diseases caused by metabolism and lifestyles.

A personalized approach is taken by AYUSH practitioners-a posture that reflects the prakriti of a person, unique constitution-and then planning his treatment. It has a sort of preventive approach to chronic diseases not only curing but also treating at the root, which has become a viable option for long-term health management.

AYUSH and Mental Health: A Holistic Approach

With a better approach toward mental health, AYUSH encompasses an all-inclusive approach. It focuses on the very important aspects of both the mind and the body. Yoga and meditation practices facilitate management of mental health, regulation of anxiety, and enhancement of emotional well-being. Pranayama helps in developing increased mental clarity and serenity.

This perspective conceives mental disorder more as a disease of the whole person, hence the inclusion of treatments such as abhyanga therapeutic massage and shirodhara oil treatment to pacify the thoughts. Homeopathy is a gentle treatment to help with the symptoms of depression and anxiety as well as insomnia in order to help restore emotional equilibrium.

But, the AYUSH/CAM therapies emphasize self mindfulness and self awareness which are very important for building mental endurance. Such an integrative method is in keeping with the current situation in India whereby there is increased demand for mental health services provision and offers a feasible and affordable means of supporting mental health.

The Role of AYUSH in Building a Sustainable Health System for India

This would place the development of AYUSH in the country’s health care context as another giant step forward in promoting sustainable health care. Inclusion of AYUSH will be beneficial because it will promote blended approaches with modern medicine so that solutions can be made available to the country’s population particularly those living in the rural areas. The contribution of AYUSH to a healthy sustainable future reaffirms its role in the following ways:

Affordable Healthcare: The cost of AYUSH treatments does not strain the financial resources of the patient families making them prove useful to cheap household.

Available in Remote Areas: More and more AYUSH clinics and dispensaries are starting up in the country side so that the very far off people can readily access health services.

Promoting the Local Wisdom: The support to the AYUSH system has also contributed towards the preservation of the rich cultural diversity of the country and allows local people to manufacture and market medicines made from the plants.

Such government initiatives, through National AYUSH Mission, have sought to improve the delivery of AYUSH services in an integrated manner with modern medicine and reached maximum public coverage and awareness. As more people start adopting these practices, AYUSH is the surest way through which India can convert its present healthcare system into a sustainable and deeply traditional one.

Conclusion

As India strives for a healthier future, AYUSH emerges as a valuable tool in addressing modern health challenges. This integrated wisdom of Ayurveda, Yoga, Unani, Siddha, and Homeopathy finds expression in AYUSH’s balanced approach with a greater emphasis on prevention, natural healing, and mental well-being. At a time when the world is looking toward wellness and sustainable health care, India through its AYUSH practices provides not just an interface with the traditional knowledge but also a pathway to building a healthier and more resilient nation. AYUSH represents an investment in a holistic future where health is that state of complete physical, mental, social and spiritual well-being and not merely the absence of disease.

[insuradvisor]

Why AYUSH Health Insurance is Essential in India’s Evolving Healthcare Landscape

India’s healthcare landscape is evolving, with an increasing number of people turning to alternative therapies such as Ayurveda, Yoga, Unani, Siddha, and Homeopathy (AYUSH). These treatments offer a holistic approach to health and wellness, addressing both the body and mind. To cater to this growing demand, AYUSH health insurance has emerged as a vital tool, offering financial coverage for individuals seeking natural and traditional treatments alongside modern medicine.

Here’s why AYUSH health insurance is a crucial part of India’s healthcare system:

Addressing the Demand for Alternative Medicine: In recent years, there has been a surge in the popularity of alternative medicine across India. Many individuals are opting for AYUSH therapies, either as standalone treatments or alongside conventional medical care. AYUSH health insurance ensures that people have access to these treatments without the financial strain, making it easier to choose natural remedies.

Fostering a Preventive Healthcare Approach: AYUSH systems focus on preventive care, helping individuals maintain overall health and avoid illness through lifestyle practices and natural treatments. Health insurance policies that cover AYUSH treatments promote this preventive approach, allowing policyholders to seek regular care that prevents the onset of more serious conditions.

Support for Chronic and Lifestyle Diseases: Many chronic and lifestyle-related diseases, such as diabetes, hypertension, and arthritis, can be managed effectively through AYUSH therapies. AYUSH health insurance allows individuals suffering from these conditions to explore alternative treatments that may offer relief and long-term benefits, without the worry of high medical costs.

Holistic Care for Mental Health: AYUSH systems, particularly Yoga and Ayurveda, are known for their benefits in managing mental health issues like anxiety, depression, and stress. Health insurance that includes AYUSH therapies ensures that individuals can seek mental health support through holistic methods, offering a comprehensive approach to well-being.

Encouraging Health Equity: AYUSH health insurance helps bridge the gap between traditional and modern healthcare systems, providing coverage for a wider variety of treatments. This makes healthcare more equitable, ensuring that both rural and urban populations can access the type of care that suits their needs and preferences.

In-Depth Insights on AYUSH Health Insurance from SMC Insurance

For individuals looking to explore the benefits of AYUSH health insurance, SMC Insurance offers a detailed guide. Their article covers all aspects of AYUSH health insurance, including the scope of coverage, policy options, and how these treatments can complement conventional healthcare.

To gain a deeper understanding of AYUSH health insurance, you can read SMC Insurance’s comprehensive article on “AYUSH Health Insurance”. This guide provides valuable insights to help you choose the right policy for your healthcare requirements.

Ensure your health is covered through both natural and modern methods by opting for AYUSH health insurance, with expert guidance from SMC Insurance!

[kavirajpharmaceuticals]

Exploring the benefits of kaviraj pharaceuticals siddha ayurvedic medicine

"The Power of Kaviraj: Proprietary, Ayurvedic, and Siddha Medicines for Optimal Health"

The world of medicine is constantly evolving and expanding, with new treatments and remedies being discovered every day. However, in the midst of all the modern advancements, there are still traditional forms of medicine that have been used for centuries and continue to be relied upon by many. Kaviraj Pharmaceuticals is a prime example of a company that combines ancient knowledge with modern techniques to produce high-quality medicines that promote optimal health.

With over 40 proprietary medicines, 82+ ayurvedic medicines, and 150+ siddha medicines, Kaviraj Pharmaceuticals has a wide range of products to cater to various health concerns. And it doesn't stop there - their line of Kaviraj Foods and Herbals as well as Yavvana Care products add even more options for individuals looking to maintain their well-being.

One of the key factors that sets Kaviraj Pharmaceuticals apart is their GMP certification. This means that their medicines are prepared in a clinically clean environment, with the highest standards of plant hygiene, personal hygiene, and product hygiene. This attention to detail ensures that the medicines produced are of the highest quality and meet strict safety standards.

But what exactly are proprietary, ayurvedic, and siddha medicines? And what makes them so effective in promoting good health? Let's take a closer look.

Proprietary Medicines:

Proprietary medicines are those that are developed and produced by a specific company and are protected by trademark or patent laws. Kaviraj Pharmaceuticals takes great pride in their extensive range of proprietary medicines, which includes remedies for various ailments such as respiratory issues, digestive problems, skin conditions, and more.

What sets proprietary medicines apart is that they are made using a unique formula or composition developed by the company. This means that they cannot be replicated by other manufacturers, making them exclusive to Kaviraj Pharmaceuticals. Additionally, these medicines have undergone rigorous testing and quality control measures to ensure their effectiveness and safety.

Ayurvedic Medicines:

Ayurveda is an ancient Indian system of medicine that focuses on balancing the mind, body, and spirit to achieve optimal health. It is based on the belief that every individual is unique and therefore requires a personalized approach to healing. Ayurvedic medicines are natural remedies made from herbs, minerals, and other plant-based ingredients that work in harmony with the body to promote balance and well-being.

Kaviraj Pharmaceuticals offers a wide range of ayurvedic medicines, including herbal tonics, capsules, powders, and oils. These medicines are prepared using traditional methods and follow strict quality control measures to ensure their authenticity and effectiveness. They are also free from harmful chemicals and additives, making them safe for long-term use.

Siddha Medicines:

Siddha medicine is another traditional Indian system of healing that originated in the southern region of India. It is based on the concept of balance between the five elements - earth, water, fire, air, and space - within the body. Siddha medicines are made from natural ingredients such as herbs, minerals, and animal products and are believed to work by restoring balance and harmony within the body.

Kaviraj Pharmaceuticals takes great care in preparing their siddha medicines using ancient techniques and following strict quality control measures. These medicines are known for their effectiveness in treating chronic conditions such as arthritis, diabetes, and skin diseases.

The Power of Kaviraj Foods and Herbals:

In addition to their line of medicines, Kaviraj Pharmaceuticals also has a range of foods and herbals that can support overall health and well-being. These include herbal teas, juices, powders, and supplements made from natural ingredients such as amla (Indian gooseberry), turmeric, and neem. These products are a great way to incorporate the benefits of tradition.

To know more : https://kavirajherbals.co.in/pharmaaceuticals/

[healthcaretechnologynews]

Research on Fenugreek

At GRG Health, we often find that what our research reveals is eventually confirmed by sundry unrelated sources (though at a somewhat later date).

Recently, #research conclusively showed that a solution of #Fenugreek and water (popular as "Methi water" in Hindi) is helpful in #weightloss (please note that #galactomannan induced fullness in the GI tract is just one aspect here) and even supports insulin sensitization (with implication for #glycemiccontrol and #diabetes).

Write to us at enquire@grgonline.com to learn how GRG Health is helping clients gather more in-depth market-level information on such topics.

The news about that research on Fenugreek was carried across public channels incl. this one:

https://lnkd.in/dU4F5RT9 .

However, well before this news appeared, GRG Health had closed an in-depth engagement for a key #client, identifying not just Fenugreek but many dependable/robust candidates that are supported by scientific evidence (for further R&D and incorporation into the client's own product portfolio).

As this was an in-depth engagement, GRG Health found not just the ingredients but their core nutrients/components (like the Galactomannan in Fenugreek, for example) also, ranking them based on evidence, #expert inputs and #KOL opinion, sharing the findings with the client in a report that is currently being used for product creation.

GRG Health also posted a short summary about that engagement when the client permitted......if you missed it, check here: https://lnkd.in/dYBDa9Fq .

Traditional Medicine (incl. #Ayurveda, #Unani, #Siddha) and #Homeopathy (the pillars of India's #AYUSH initiatives) serve as rich sources of many such ingredients....if you are looking for more insights about them, reach out to GRG Health.

Read more about Fenugreek (and Galactomannan) below.

If you need a credible partner for your #Research needs, visit our website or leave us a message.....we will get back to you at the earliest!

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Avarampoo Benefits

Avarampoo, also known as Avaram Senna or Cassia auriculata, is a plant commonly found in India and other parts of Asia. It has been used in traditional Ayurvedic and Siddha medicine for its various health benefits. Here are some of the potential benefits associated with Avarampoo:

Skin Health: Avarampoo is known for its skin benefits. It can help improve complexion, reduce skin problems like acne and blemishes, and promote healthy, glowing skin. It is often used in the form of a face pack or powder mixed with water or other ingredients.

Diuretic Properties: Avarampoo has diuretic properties, which means it can help increase urine production. This can be beneficial for people with urinary tract problems and may help in reducing water retention.

Digestive Aid: It is believed to aid in digestion and can be used to relieve digestive issues like constipation and indigestion. It is often consumed as a tea or decoction for these purposes.

Antioxidant Properties: Avarampoo contains antioxidants that can help neutralize harmful free radicals in the body. This may contribute to its anti-aging properties and overall health benefits.

Regulating Blood Sugar: Some studies suggest that Avarampoo may have a positive effect on blood sugar levels and could be beneficial for individuals with diabetes. However, more research is needed in this area.

Anti-inflammatory: Avarampoo may possess anti-inflammatory properties, which can be helpful in reducing inflammation in the body and relieving conditions like arthritis and joint pain.

Weight Management: Some traditional uses of Avarampoo include using it as a natural remedy for weight management. It may help in reducing excess body fat and promoting weight loss when consumed regularly.

Hair Care: Avarampoo can also be used for hair care. It is believed to strengthen hair and promote hair growth. It can be used in the form of a hair pack or hair rinse.

Wound Healing: In traditional medicine, Avarampoo has been used for wound healing and as a topical treatment for various skin issues. It is applied as a paste to the affected area.

It's important to note that while Avarampoo has been used for these purposes in traditional medicine, scientific research on its efficacy and safety is limited. Always consult with a healthcare professional before using herbal remedies, especially if you have underlying medical conditions or are taking medication. Additionally, the dosage and preparation methods can vary, so it's essential to follow proper guidelines when using Avarampoo or any herbal remedy.

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Empowering Men's Health: Unveiling 18 Proven Shilajit Benefits

Numerous studies have shown that men are more prone to illnesses than women. However, the key to preventing men's diseases lies in harnessing the power of organic substances. Shilajit, a unique and potent organic substance, offers a plethora of benefits for men, including improved heart health, altitude sickness relief, and enhanced fertility.

Today, we will delve into 18 scientifically proven Shilajit benefits for men that effectively address heart, body, and neuron-related issues.

What is Shilajit?

Shilajit is a sticky, tar-like resin found in the rocks of mountain ranges, particularly the Himalayan, Tibetan, and Altai mountains. It boasts a rich history of use in Indian traditional medical practices like Ayurveda, Siddha, and Unani. Renowned for its numerous health benefits, Shilajit is often used to promote overall well-being, vitality, and longevity.

Comprising a myriad of amino acids, vitamins, glycerol, and medicinal properties, Shilajit possesses potent antioxidant and nutritional qualities, with specific advantages for male reproductive health.

18 Proven Shilajit Benefits to Improve Men's Health

Shilajit, an Ayurvedic herb with theopathic effects, not only improves men's health but also enhances overall well-being. Let's explore the 18 remarkable benefits of Shilajit:

Increase Testosterone Level: Shilajit aids in boosting testosterone levels, vital for male reproductive tissue growth and the development of secondary sexual characteristics. It can help counter the natural decline in testosterone levels as men age, potentially increasing sperm count.

Combat Obesity: Shilajit has the potential to fight obesity and fatigue by boosting metabolism, burning calories, and aiding in weight loss. It also helps control sudden hunger pangs, preventing overeating.

Relieve Chronic Fatigue: Shilajit's adaptogenic properties alleviate symptoms of chronic fatigue and enhance overall cell function, improving stamina.

Reduce High Cholesterol: Shilajit's antioxidant properties protect cells from damage and help maintain healthy blood pressure and pulse rate, reducing the risk of heart disease.

Treat Wounds: Shilajit's anti-inflammatory properties promote tissue regeneration, speeding up the body's wound-healing process.

Treat Liver Disease: Shilajit can support liver health by combating cancerous cells and promoting overall liver efficiency.

Prevent Anemia Fast: Shilajit supplements can gradually increase manganese, copper, and iron levels, helping combat anemia caused by a lack of hemoglobin.

Help in Digestion: Shilajit aids digestion and nutrient absorption in the gastrointestinal tract, making it beneficial for those experiencing digestion issues.

Improve Cardiovascular Health: Shilajit's iron, copper, manganese, and fulvic acid content contribute to a defensive line against heart disease and toxins.

Improve Metabolism: Shilajit contains digestive fiber, aiding the body in ridding itself of toxins, improving mood, and providing more energy.

Manage Diabetes: Shilajit's fluvic acid neutralizes free radicals that harm pancreatic beta cells, helping restore insulin release and removing toxins from the body.

Strengthen Hair Quality: Shilajit's zinc, magnesium, and fluvic acid content strengthen and improve overall hair health.

Lower Your Risk of Aging: Shilajit's fluvic acid acts as an antioxidant, helping reduce oxidative stress and the risk of premature aging and cell deterioration.

Support Fertility: Shilajit can naturally increase sperm count by 12% when taken regularly for 90 days.

Improve Flexibility and Joint Mobility: Shilajit's minerals and phytochemicals strengthen ligaments and muscles, improving flexibility and joint health.

Improve Energy and Stamina: Shilajit's antioxidant properties boost mitochondrial performance, providing increased energy and stamina.

Alzheimer's Disease: Shilajit's memory-enhancing properties, like fulvic acid, protect neuron cells from oxidative stress, potentially benefiting cognitive function.

Help with Altitude Sickness: Shilajit's adaptogenic qualities aid the body in handling stressors, making it useful for alleviating altitude sickness symptoms.

In Conclusion

Shilajit is a core ingredient in Ayurvedic medicine, offering numerous health benefits. Embrace Shilajit to improve your overall health and protect yourself from serious illnesses. Share your experiences with us as you reap the benefits of this remarkable natural substance!"

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The increase in blood glucose level, also commonly referred to as general diabetes is a medical condition that is caused due to certain metabolic disorder where the body is either unable to secrete insulin to break the blood glucose or the inability of the body to absorb the excess glucose in the blood.  When this disorder is not taken care off, it leads to other ailments like, increase in blood pressure, cardiac problems, etc., Herbal Health care using the conventional siddha medicine treats this disorder with natural indigenous herbs that has the property to stimulate insulin secretion in the body and to give a complete cure from diabetes. Our treatment is also accompanied by simple body exercises and diet control to give the most effective cure for Diabetes Mellitus.

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Ayurvedic Medicine Buy Online from Urban Muni online shop. Here you will get more products related skin care and wellness as well. Here so many items are available for selling at reliable prices. Our shop is the best spot for regarding healthcare, personal grooming, family care and wellness gear etc. Visit and see what you want. If you want consult with doctor's you can do too from here at comfort budget.

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Why AYUSH Health Insurance is Gaining Importance in India

In India, traditional forms of medicine like Ayurveda, Yoga, Unani, Siddha, and Homeopathy (collectively known as AYUSH) have been practiced for centuries. These systems focus on holistic healing and preventive care, often appealing to individuals who prefer natural, alternative treatments. As the popularity of AYUSH therapies continues to rise, health insurance policies that include these treatments are becoming more essential.

Here’s why AYUSH health insurance is increasingly important:

Increased Demand for Natural Healing: With more people turning towards alternative therapies, particularly in the wake of the global health crisis, AYUSH health insurance addresses the growing demand for treatments like Ayurveda, Yoga, and Homeopathy. Offering coverage for these therapies ensures that people who prefer natural treatments are financially supported while receiving healthcare.

Government Promotion of AYUSH: The Indian government has been actively promoting the use of AYUSH therapies, emphasizing their role in preventive and holistic healthcare. Insurance policies that cover AYUSH treatments align with the government’s vision and help people access affordable, natural healthcare options.

Holistic Coverage for Lifestyle Disorders: Many modern health issues, such as diabetes, hypertension, and obesity, can be effectively managed with AYUSH therapies. Health insurance plans that cover AYUSH treatments provide comprehensive solutions for individuals looking for holistic ways to manage lifestyle disorders and chronic ailments.

Affordable Alternative Treatments: AYUSH treatments are often more affordable than conventional medical procedures, making them an appealing option for many. AYUSH health insurance makes it even easier to access these cost-effective treatments without financial strain, ensuring that healthcare remains affordable for all.

Broader Treatment Options: AYUSH health insurance expands the scope of healthcare, offering policyholders a range of treatment options. Whether individuals want to undergo modern medical treatments or prefer traditional therapies, AYUSH insurance ensures they have a choice without having to worry about expenses.

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Get Asthma Treatment In Siddha Tamil And Siddha Treatment for Diabetes

Siddha medicine is the ancient medicine found to cure many diseases which include asthma, diabetes, kidney stone, kidney failure piles, psoriasis, infertility, asthma, etc. Siddha provides a permanent relief for many major ailments to minor ailments.This Siddha medicine provides SiddhaTreatment for Diabetes in an effective way.  In our hospital, we provide Siddha treatment in the best way.

So if you are looking for Asthma Treatment In Siddha Tamil? Then reach diawin Siddha hospital and get Siddha Medicine For Sugar In Tamil. Diabetes is the major problem everyone is facing. Diabetes is classified into type 1 and type 2  diabetes.

So to get Siddha Treatment For Asthma and diabetes and to cure diseases, Siddha council has formulated the Siddha group of medicine. Our medicines have ISO Certification and approved by international medical council.  So don’t  wait reach our diawin Siddha hospital to cure diseases and lead a happy life. Reach us now..

[lupinepublishers]

Lupine publishers|A Brief Review on Phytochemical and Pharmacological Aspects of Andrographis Paniculata

A Brief Review on Phytochemical and Pharmacological Aspects of Andrographis Paniculata

Abstract

Andrographis paniculata is an important herbaceous medicinal plant belonging to the acanthaceous family. It is native to India, China, and Southeast Asia. It is also known as “Kings of bitters”. Andrographis paniculata has traditionally been used to treat a

variety of ailments such as fever, high blood pressure, ulcer, colic, leprosy, influenza, diabetes, and malaria. The importance of

Andrographis paniculata is also described in the literature of the Unani, Ayurveda, and traditional systems of medicine. A.paniculata

contains several chemical compounds with distinct biological properties. The major active chemical compound found in

A.paniculata is andrographolide. All the plant part contains the bioactive compounds and used for the different purposes. However, the composition of the active compounds also depends on the plant parts used, the geography of the plant, time of harvest, and the season. A. paniculata possess a broad spectrum of pharmacological activity such as anti-bacterial, anti-diarrheal, anti-diabetic, anti-

inflammatory, anti-malarial, and hepatoprotective activity. This review explores the phytochemical and pharmacological aspects of

the Andrographis paniculata.

Introduction

Since the beginning of civilization, medicinal plants have been an intrinsic component of human life [1]. The conservation of eth-nobotanical knowledge as part of living culture and practice be-tween communities and the environment is essential for biodiversi-

ty conservation. The information about medicinal plants gains from

various medicinal systems such as Unani, Siddha, and Ayurveda [2].

The traditional system of medicine belongs to the traditions of each

country and has been passed over from generation to generation. Understanding the dynamics of traditional local knowledge of me-dicinal plants is important for their medicinal properties is now be-

ing developed as a source of scientific research to prove the effect

of plants and generate new therapeutic resources. Medicinal plants are considered as a backbone of traditional medicine (WHO) as well as most modern medicine is also derived from medicinal plants i.e.

aspirin. The medicinal plant having a rich source of components that can be used to develop and synthesize drugs. About 3.3 bil-lion people in developing countries depend on medicinal plants on a regular basis, WHO estimated that about 80% world population rely on the medicinal plant for their primary health care. Further more, worldwide 42% of 25 top-selling drugs marketed are either directly obtained from natural sources or entities derived from

plant products [3]. The quality of traditional medicine is deter-mining its active substances produced by the plant. Andrographis paniculata is one of the important medicinal plants that is utilized

throughout the world [4]. A.paniculata is an herbaceous plant of the Acanthaceae family. It is widely distributed in Southeast Asia, India, and tropical as well as in subtropical Asia. A.paniculata is also known as the “King of Bitters” since it has a highly bitter taste in all parts of the plant body [5]. Furthermore, A. paniculata is known

as “Kalmegh” in India, “Chuan-Xin-Lian” in China, “Fah Tha Lai” in Thailand, “Hempedu Bumi” in Malaysia, “Senshinren” in Japan, and

“green chiretta” in Scandinavian nations [6]. A.paniculata is one of the most widely used plants in Ayurvedic and Unani medicine [4].

Traditionally, A.paniculata was used in the treatment for snake-bite, fever, bug bite, diabetes, malaria, and dysentery [7]. Moreover,

A.paniculata is also used in the combination with other herbs and health care treatment. It is found that A.paniculata is used in more

than half of the herbal formulations commercialized in India for he-patic diseases [8]. Many scientific studies also have been reported

regarding the medicinal properties possessed by the A.paniculata,

most of which are based on traditional knowledge (Table 1). Phyto-chemical investigations have revealed that A. paniculata contains a

wide range of chemicals. In addition, experimental evidence also re-ported that A.paniculata has a broad spectrum of pharmacological

activity including anti-bacterial, antidiarrheal, anti-inflammatory,

antiviral, antimalarial, anticancer, antimalarial, hepatoprotective,

etc. In this review, we briefly discuss ethnobotanical uses, phyto-

chemistry, and recent scientific finding pharmacological activity of

the A.paniculata [6]. Botanical Description and Habitat

A.paniculata is native species of India, China, and Taiwan. But it

is also found in Southeast Asia, tropical and subtropical Asia as well as few other nations such as Malaysia, Indonesia, Vietnam, Sri Lan-ka, Laos, Cambodia, Pakistan, Myanmar, and the Caribbean islands [9]. Especially, in India A.paniculata are found in Karnataka, Andhra

Pradesh, Tamil nadu, Uttar Pradesh, and Madhya Pradesh. Also cultivated in Assam and West Bengal to some extent. In addition,

A.paniculata are found in different habitats including forests, farms, plains, hill slopes, dry and wetlands, and wastelands [10]. A.panic-ulata is bitter in test, an annual herb that is abundantly branched which grows up to a height of 3.-110 cm in a humid, shady area. It has glabrous leaves that are 8.0 cm long and 2.6 cm wide, little

white flowers that are rose-purple or light pink, spots on the pet-

als, and corolla with hairs. The stem was found to be dark green in color, 0.4-1.0 m tall, 2-6 mm in diameter, quadrangular with longi-tudinal furrows and wings on the angles of the younger part [11] as shown in Figure 1Volume 2 - Issue 5LOJ Phar & Cli Res.Citation: Asha Humbal, Neha Chaudhary, Supriya Vaise and Bhawana Pathak*. A Brief Review on Phytochemical and Pharmacological Aspects of Andrographis Paniculata. LOJ Phar & Cli Res 2(5)- 2021. LOJPCR.MS.ID.000148. DOI: 10.32474/LOJPCR.2021.02.000148Copyrights @Bhawana

Pathak 266

Traditional Uses of Andrographis Paniculata

A.paniculata play vital importance in the Ayurvedic, Siddha, and traditional medicine systems in India [12]. For centuries, the leaves and roots of A.paniculata have been used to treat a wide range of health problems in Asia and Europe. However, the entire plant is

also utilized for specific uses [13]. The plant known as “Kalmegh”

in Ayurvedic literature is an essential element in the majority of

Ayurvedic remedies and is officially recognized by Ayurvedic phar-macopeia. Moreover, it is used as an aperient, emollient, astringent,

anti-inflammatory, diuretic, anthelmintic, carminative, and anti-pyretic in the Unani system of medicine [14].In India, tribal groups used this herb to cure a number of diseases such as antidote against

snake bites, Banded Krait and Russell’s viper, etc. [14]. The tribal

of Kheria, Khatra, Moora, and the Santal region of Bankura district,

West Bengal, India utilizes an infusion of the entire plant to treat fever [15]. The extracted juice from A.paniculata leaves, alone or combined with cloves, cinnamon, and cardamom is used as a cure

for flatulence, loss of appetite, griping, diarrhea in children, and ir-

regular stool. In India during the influenza epidemic in 1919, A.pa-niculata was shown to be highly effective in reducing the disease

progression [16]. It was also utilized by ancient Chine’s physicians to treat inflammatory diseases, colds, laryngitis, and fever, hep-atitis, pneumonia, respiratory infections, tonsillitis, sores, pelvic

snake bites, herpes zoster and it has been characterized as a cold property herb [13] to remove toxins and body heat. The decoction

of fresh leaves of A.paniculata is used as an antihypertensive and antidiabetic in Malaysian folk medicine. Furthermore, it is advised to use it in cases of leprosy, scabies, gonorrhea, boils, chronic and seasonal fevers, and skin eruptions, due to its “blood purifying” pu-rifying properties [4].

Phytochemistry

The aerial part (leaves and stems) of A. paniculata contains major active phytochemicals [17]. According to the survey of the literature, andrographolide is the major bioactive compound found in the A.paniculata which is a diterpene lactone that is crystalline,

colorless, and has a bitter taste [9]. The leaves have the highest

concentration of andrographolide about 2.39% whereas the seed

has the lowest concentration about 0.58%. The quantity of the

phytochemicals varies widely depending on the portion used, lo-cality, time of harvesting, and season (Figure 2). Andrographolides

are highest found immediately before the flowering season, then

decline progressively [14]. Other lactones compound observed in A.paniculata is 14-deoxy-11-andrographolide, 14-deoxy-11,

12 didehydroandrographolide, andragraphan, andrographon,

14-deoxyandrographolide, neoandrographolide, deoxyandrog-raphiside, andrographosterol, andrographiside etc. A.paniculata

also contains Xanthones and quinic acid derivatives in minor con-centrations. Moreover, Reddy et a. [18] reported that A.paniculata

contains flavone such as 5-hydroxy-7’2’6’-trimethoxyflavone and 23-C terpenoid 14-deoxy-15-isopropylidene-11, 12- didehydroan-

drograholide and other flavonoid Skullcapflavone I 2’-O-glucoside,

7-Omethylwogonin, 7-Omethyldihydrowogonin and 7-O-methyl-wogonin 5-O-glucoside as well as diterpenoids such as isoandro-

grapholide 14-deoxy-11, 12 didehydroandrographolide. Rao et al. [19] identified and isolated 5, 7, 20, 30-tetramethoxyflavanone and 5-hydroxy-7, 20, 30-trimethoxy flavone from the A.paniculata. A new labdane type diterpenoid which is andropanolide along with

seven known diterpenoids isolated from the methanolic leaves ex-tract of A.paniculata [20]Pharmacological Activity of A.Paniculata

Hepatoprotective activity

A.paniculata is widely used as a hepatoprotective and hepa-

tostimulative agent in the Indian traditional medicine system. Tra-

ditionally the leaves aqueous extract of A.paniculata is used in the treatment of jaundice and different liver damage. Andrographolide found in the A.paniculata was protective against liver damage in rats and mice induced by carbon tetrachloride. Moreover, Andro-

grapholide also observed significant hepatoprotective against vari-ous types of liver damage, induced by galactosamine or paracetamol

[21]. The free radical scavenging activity of andrographolide has a significant hepatoprotective effect by lowering lipid peroxidation

malondialdehyde product as well as by maintaining glutamic py-ruvate transaminase, alkaline phosphatase, and glutathione levels in mice treated with carbon tetrachloride [22]. A.paniculata has

been shown antihepatotoxic activity against plasmodium berghei

K173-induced hepatic damage in mastomys natalensis [23].

Antibacterial activity

A.paniculata has been shown the antibacterial activity against a

wide range of bacterial species. In vitro study found that the aque-

ous extract of A.paniculata shown antibacterial activity even at the low concentration (25 mg/ml) against E.coli, Shigella, Streptococci, Staphylococcus aureus, and Salmonella [24]. Another similar study

leaves aqueous extract of A.paniculata reported against the methi-cillin-resistant S.aureus and Pseudomonas aeruginosa [25]. Further-more, A.paniculata is also effective against HAS 1 (herpes simplex virus 1) without any cytotoxicity [26].

Antidiarrheal activity

In developing countries, Diarrhea is one of the most common diseases and it leads to the top ten causes of death among children worldwide [5]. Some drugs such as kaolin-pectin, selenium, loper-amide, and bismuth have been used to treat the symptoms. How-ever, it also causes some unfavorable side effects [5]. The study has been found that A.paniculata has significant antidiarrheal proper-ties [27]. According to the study, an ethanolic extract of A.panicu-lata treated 88.3 % of acute bacillary dysentery cases and 91.3% of acute gastroenteritis cases. Furthermore, andrographolide was found to treat 91% of acute bacillary dysentery cases. The same cure rate of about 91.1% was obtained by providing a compound tablet comprising andrographolide and neoandrographolide in a 7:3 ratio. This was claimed to be more than the cure rate observed with chloramphenicol and furazolidone [28]. A.paniculata was found to be effective in curing patients with acute diarrhea and bac-illary dysentery in double-blind investigation [14].

Antimalarial activity

In many tropic and subtopic countries, malaria is still a preva-lent disease [14]. A.paniculata was shown to significantly suppress

the growth of the Plasmodium berghei [11]. In vitro study of 50%

ethanolic extract of the aerial parts (100 mg/g) shown antimalar-ial activity against plasmodium berghei and in vivo study in rats observed antimalarial activity after intragastric application (1g/kg body weight) [26]. It is suggested that the antimalarial effect of A. paniculata is due to the reactivation of the enzyme superoxide dis-

mutase [5]. Another study has been reported that the crude extract

of A.paniculata shown antimalarial activity against the resistant

strain of Plasmodium falciparum having an IC50 value of 6mg/ml

[29]. In addition, a xanthous compound isolated from the A. panicu-lata has been shown in vivo antimalarial activity in plasmodium in-

fected Swiss albino mice. The results found that a significant reduc-tion in parasitemia after treatment with a 30 mg/kg dosage [26].

Anticancer activity

Cancer is a set of disorders characterized by abnormal cell pro-liferation and the ability to penetrate or be spared to other regions of the body. Despite the fact that many diseases have a worse prog-

nosis than most cancers [17]. The extract of A.paniculata having

diterpenoid is significantly able to restrict cell proliferation, arrest

the cell cycle and induce cell apoptosis of different cancer cells [30-

33]. Treatment of the MDA-MB-231 breast cancer cells with andro-

grapholide extracted from A. Paniculata causes apoptosis of cancer cells and arrests the cell cycle without interfering with the normal

growth of cells [34]. The study has been reported that A.paniculata

exhibits potent cytotoxic activity against human epidermoid carci-noma of the skin lining of the lymphocytic leukemia cells and na-

sopharynx [12]. A.paniculata also shown cytotoxic effects against colon cancer cells by suppressing AKT and mTOR phosphorylation

levels, resulting in ER stress-induced death [35]. Furthermore, apoptosis in colon cancer cells is induced by the andrographolide via controlling the signaling of pro-apoptotic GRP-78/IRE1/XBP-1/CHOP [17].

Antidiabetic activity

Diabetes is a metabolic disease characterized by elevated blood

sugar levels [36]. According to the WHO reports around 70 million

people worldwide suffer from diabetes. Specifically in developing

countries, diabetes has become a threat to human health [37]. In vivo study observed that ethanolic extract of A.paniculata exhibit

the protective effect in hyperglycemic condition and also protect

the tissue damage caused due to oxidative stress in a diabetic rat model produced by streptozotocin [38]. Another study conduct-ed [39] found that oral administration of andrographolide in a dose-dependent manner reduced plasma glucose levels in diabetic

rats caused by streptozotocin and wild-type rats.

Conclusion

The entire literature review indicated that Andrographis paniculata exhibits a broad range of phytochemicals and pharmacological activities. The previous study found that

A.paniculata contains 50 lactane diterpenoids, 30 flavonoids, and 30 novels phytochemical isolated and identified from A.paniculata. Phytochemical study reveals that Andrographolide is a major compound found in Andrographis paniculata. It has shown a wide spectrum of pharmaceutical activity such as anti-microbial,

hepatoprotective activity, anti-inflammatory activity, anti-malarial, anti-diarrheal, anti-diabetic, and cytotoxic activity. The precise

information offered as a review here covers the phytochemical and pharmacological information about this plant, providing the much-needed encouragement to use this plant in creating and sustaining a prospective means of livelihood.

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