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xtruss · 1 year ago

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What is the Fastest Missile in the World and How Much Does Speed Really Matter?

— Ilya Tsukanov | Sunday May 21st, 2023

Russia’s Kh-47M2 Kinzhal hypersonic missile made the news this week after destroying a Patriot radar station and five launchers in overnight strikes in Kiev on May 16. How did the Kinzhal get through? What other countries possess ultrafast missiles? Why is it that speed isn’t always everything? Check out our explainer to find out.

According to independent US media, the Patriots fired off as many as 32 interceptor missiles at the Kinzhals targeting them in a desperate attempt to intercept them. The Pentagon went into damage control, mindful that admitting the missile defense system’s weaknesses against Russian missiles would undermine global faith in the superiority of US weapons. Patriot missile maker Raytheon saw up to $10 billion shaved from its stock valuation over the news that its coveted weapons system had been hit.

US officials claimed the systems were “damaged,” but assured that they had not been destroyed. Ukraine’s military, meanwhile, claimed that it shot down six Kinzhals without losing any Patriots. The Russian military offered no comment.

But what else does Russia have in its missile arsenal?

What is the Fastest Russian Missile?

The Kinzhal is one of the speediest and most advanced missile systems in Russia's arsenal, but not the only one. The weapon is an air-launched hypersonic missile with a range of between 2,000 and 3,000 km, and a reported speed of Mach 10 (11,925km per hour) or even higher. The Patriot’s interceptors are significantly slower, capable of accelerating to Mach 2.8 (3,340 km/h) in the case of the PAC-1, and Mach 4.1 (5,000 km/h) in the case of its PAC-2 and PAC-3 variants.

The Kinzhal is not the fastest missile in Russia’s arsenal, with the strategic RS-28 Sarmat, and the submarine-launched Bulava missiles capable of accelerating to speeds of up to Mach 20 (25,500 km/h) and Mach 24 (28,600+ km/h), respectively. And while these are not hypersonic missiles, but ballistic weapons which travel into space and then release warheads that fall to Earth, they are capable of maneuvering like their hypersonic cousins (Bulavas at their boost stage, Sarmat warheads as they approach targets, or Avangard hypersonic glide vehicles fitted aboard Sarmats), theoretically making their interception impossible. Theoretically, because these weapons have never been tested in actual warfare, and, hopefully, never will, because their use would likely signal the start of a Third World War.

When it comes to missiles, speed isn’t everything, and the lower intercept speed wouldn’t be a problem if the Patriot were locking on to a traditional ballistic missile flying on a known trajectory. The problem is, missiles like the Kinzhal are capable of maneuvering in flight, making course corrections to make it more difficult to predict its trajectory and exact course.

Russia’s Sarmat ICBM Can Change Trajectory, Will Make Interception Hardly Possible in Coming Decades! "...today, they say that air defense does not exist for the Sarmat missile system, and it probably will not exist in the coming decades," Col. Gen. Sergei Karakaev, commander of Russia’s Strategic Missile Forces predicted. © Sputnik/Press Service of the Ministry of Defense of the Russian Federation/Go to the mediabank

What is the Number One Fastest Missile in the World?

Determining a missile’s maximum speed depends on definitions. As stated above, strategic intercontinental ballistic missiles typically have the highest speed characteristics, with the US ground-based LGM-30 Minuteman having a rating of Mach 23 (28,200 km/h), and the UGM-133 Trident II submarine-launched missile a top speed of Mach 24 in its terminal phase). The Chinese DF-41 ICBM is reportedly capable of flying up to Mach 25 (30,600 km/h), making it perhaps the fastest ballistic missile in the world today. As for hypersonics, the Avangard glide vehicle appears to enjoys the coveted top spot, with a maximum boost speed of up to Mach 27 (32,200 km) in near-space conditions (although this falls to an estimated Mach 15-20 by atmospheric drag on descent).

What is the BrahMos Missile, and Does Russia Use It?

The BrahMos ramjet supersonic cruise missile jointly developed by Russia and India carries the distinction of the fastest cruise missile in the world, with a top speed of Mach 3.5 (about 4,175 km/h) – fast enough to make short work of enemy vessels and ground-based targets and their air defenses. A new variant of the missile, the Brahmos 2, is under development, with an expected maximum speed of up to Mach 8 (9,800 km/h) thanks to innovative use of a scramjet air-breathing jet engine. The Brahmos 2 is a development of the 3M22 Zircon, a Russian scramjet-powered anti-ship cruise missile which entered into service in January.

Why are High Speed Missiles So Important to Russia’s Deterrence Doctrine?

Why does Russia seem to be at the top or near the top of most rankings when it comes to the capabilities of its hypersonic, ballistic, and cruise missiles? The answer is simple. Inheriting a massive head-start on advanced missile technology and the blueprints for the earliest hypersonic missiles from the USSR, which began work on them in the late 1960s, while missile tech was one of the areas where R&D investments was not totally curtailed in the 1990s.

A Soviet hypersonic missile design displayed at an exhibition staged by the Raduga Design Bureau. File photo. © Sputnik/Sergey Mamontov//Go to the mediabank

In 2002, after the United States unceremoniously pulled out of the Anti-Ballistic Missile Treaty, President Vladimir Putin ordered work on existing projects to be accelerated, and for new ones to be laid down, amid concerns that the creation of a US strategic missile defense system could “neutralize and render obsolete our entire nuclear potential.” These efforts bore fruit, and in 2020, Putin said that for the first time in its modern history, Russia had come to possess “the most modern types of weapons, which are far superior in terms of their force, power, speed, and, very importantly, in terms of accuracy compared to all which existed before them and exist today.”

These upgrades to Russia’s missile capabilities couldn’t have been more timely, because at the same time that Washington scrapped the ABM Treaty, the Pentagon began working on "Prompt Global Strike" – an ambitious, but highly dangerous, initiative proposing mass precision-guided conventional missile strikes to decapitate adversaries’ political and military leadership and missile deterrents, thus stripping them of the ability to retaliate to aggression.

Prompt Global Strike as envisioned in a 2014 MIT presentation. © Photo: Subrata Ghoshroy, MIT

Basically, the possession of ultra-high speed missiles capable of maneuvering, evading missile defenses, and masking their destination provide Russia with a kind of missile "shield," allowing the country’s leadership to sleep soundly at night in the knowledge that surprise enemy aggression would be met with an inevitable and devastating response – thereby deterring any itchy trigger fingers at the Pentagon and forcing it to keep ideas like Prompt Global Strike on the drawing board.

#Russia #Fastest #Missile

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bapzap · 2 years ago

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-"how do you domesticate and farm angels in df"

due to a game engine silly, angels are loyal to their site owner; as they usually only spawn in a divine vault. ie, they serve their god who created the vault. but if you use a variety of methods to find where these adventurer-only accessible vaults are, you can track the exact location down and embark a fortress onto it, changing the owner to yourself and thereby changing the angel's loyalty to yours; turning all nonsapients into game-defined pet animals. the sapients still wanna kill you though, but that means they'll kill each other (then respawn, hence farming them)

-"which hierarchy of angel are they depicted as? angel/archangel/virtue/justice/order/muse/ophanim/cherubim/seraphim? or are there different types"

in dwarf fortress the worldgen creates a variety of different forms of demons and angels unique to that worldgen, so the hierarchy (if one even exists) varies between gods as well as the specifics of said angels at all (ie some are towering serpents of steel, some are walking cloth balls that spew acid, etc). the game generates varieties of different levels of danger at "assistant", "soldier" and "archangel" ranks

the angels are usually only found in divine vaults where a demon and a god made a pact to free a demon in exchange for service (usually a war god freeing a demon so that war might never end and the demon goes on to become a god-emperor of a goblin civilization to ravage the world for centuries, a death god freeing a demon so that all might end; something similar to that. although sometimes a 'good' god will do it so that 'great heroes may rise' or 'wonderous stories may be written'); and the angels remain as guards to protect the vault holding a slab to the demon's true name that will allow a mortal to permanently banish or enslave the demon to their will

-"what are hellstone and godmetal?"

hellstone is called slade in dwarf fortress, which is an impossibly heavy stone found only in hell naturally. it cannot be used for anything due to it being indestructible by any hands but a god's, so it is impossible to use it. unless you find a divine vault, which is created by the gods and ergo has slade crafted into various items which you can deconstruct and reconstruct to use bugs to generate more from nothing depending on efficiency bonuses like that infinite chocolate post

godmetals are randomly generated divine metals created in worldgen that a deity's angels use. they're not as good as THE GODMETAL, adamantine with which the gods trapped demonkind into hell with, but the randomly genned godmetals are still generally twice as good as steel (the game's best normal metal) at cutting and being not-heavy

-"should I be concered?"

very!

just so everybody knows, the dwarf fortress community finally figured out how to domesticate and farm angels for infinite hellstone and godmetal

#dwarf fortress #god i love this game

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a-shrieking-cloud-of-bats · 2 years ago

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What kind of audience do you think you'd recommend dwarf fortress to? It definetly looks very different from anything else I played

Hmm. that's a very good question anon and I'm going to break it down.

People that like making their own fun. At the end of the day, dwarf fortress is a game that's only as meaningful as you make it, due to the random generation. If you take everything literally it's just pseudo guided actions performed by randomly generated dwarves. What is a tragic tale of a soldier going on a rampage in the fort after a siege because his cat died in the fighting is very easily reduced to simple numbers, because the underlying systems are not very complex and they do not try very hard to hide themselves. Similarly after you've gotten over the initial hump, if the narrative stuff isn't quite selling you, you have to be willing to challenge yourself. I'm currently attempting to build a boat, in the ocean, and making a nice looking port town with it. None of this holds bearing on the world or how it interacts in any major way (I don't think, anyway, it's been a while), but it's a fun project and if I end up keeping the world it will continue to exist long after I'm finished playing it. I can go there in adventure mode, and dwarves from that fort that live can show up in other forts. That's pretty satisfying, if you ask me. Probably the most important part.

On to the actual game. It's mostly a logistics game, as you're attempting to wrangle a big group of mostly autonomous dwarves into doing things that will make the fort better and bigger and more like what you want it to be. The semi autonomous part is a big part of what seperates it from say, factorio, you are not exactly working with precision tools here. About the only thing you can guarantee is that you can build what and where you want to build, and the military control is pretty direct (but not setting up the military! Oh God No). Dwarves will take personal time, dwarves will sleep, dwarves will eat, dwarves will throw parties, dwarves will make artifacts (randomly generated, so there's that first point again! is that artifact sword with broccoli on it fun or dumb? that sort've random gen thing will be happening a lot.), dwarves will generally dick around a lot without any explicit order to do so. Sometimes for a startling amount of time. But that's kind've part of the fun too, even if it's sort've frustrating sometimes.

Combat and adventure mode. I mean.... it's not nothing? I've found the military more frustrating then anything and winning direct fights is usually pretty hard. But setting up an airtight fort with loads of traps and misdirection is fun too, to the right person, I'm sure. The adventure mode combat system is sort've neat and has an impressive amount of depth but you have to grind forever to get anywhere with it and it's extremely long winded, even as deep as it can get. There's an entire thread on the DF forums (or was, it's ben a while) about dwarf martial arts and how catching incoming attacks can be used to perform various complex actions. Any game where that's possible is pretty neat! It's still very long winded and nothing is easy as a result, though. I can't really speak on this much.

That's about it.

If you want to get started yourself, look for the lazy newb pack (it's a staple, don't feel bad for using it, mostly everyone does) and a video tutorial, I dunno a modern one but people used to be reccomending krugsmash I think it was? Maybe still good? Dunno. Also the wiki, which is an exhaustive source of information, but worry about that after you're done with the GUI. The dwarf fortress GUI is absolutely jam packed with information and learning how to navigate it is task number one. It's also the thing most people get stuck on, though I think it's probably a bit less of a difficulty wall now that easier alternatives are out (rimworld, gnomoria, I guess? it never really took off honestly) and some of the concepts have been used in a different place. Though dwarf fortress is still hard to start even considering that. Thankfully it's also the easiest thing to learn through a series of youtube videos.

You're never really Done learning the nuances of the UI but once you know how to make your dwarves do things, and how dwarves do things, you're through most of the meta difficulty that you don't impose on yourself.

I hope that helped! I kind've went on a bit.

#bats replies #dwarf fortress posting

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kai-lee-duudles · 3 years ago

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The first of many pictures for my Digimon Frontier AU: “DF: Next Gen”.

I’ll post about the AU in more detail later, but the gist of it is this summary here.

“Hundreds of years in the future after the defeat of Lucemon, the digital and human worlds are intertwined. Humans and digimon are living side by side, with digimon and human partners now extremely common.

However, new bearers of the warrior spirits have begun to emerge, which only mean that a new threat is on the horizon.

This tale follows the new Agnimon as he awakens from a years old slumber, and to a blank memory. Alongside him is Annie, a young woman who becomes one of Agnimon’s closest friends and is determined to help him discover his missing past.”

The best thing I can hope for is that ya’ll fall in love with this AU as much as I have, because this is the thing I’ve been obsessing over for the past 2 weeks now. Anyways, thanks for letting reading, and stay tuned folks!

Edit: I forgot to mention something. Bossardimon is right, new/Next Gen Agnimon is a himbo to the T. 😂

#digimon #digimon frontier #AU #Future AU #Agnimon #Annie KJ #DF: Next Gen

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greatworldwar2 · 4 years ago

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• Hanna Reitsch

Hanna Reitsch was a German aviator and test pilot. Along with Melitta von Stauffenberg, she flight tested many of Germany's new aircraft during World War II and received many honors. She set more than 40 flight altitude records and women's endurance records in gliding and unpowered flight, before and after World War II.

Reitsch was born in Hirschberg, Silesia (today Jelenia Góra in Poland) on March 29th, 1912 to an upper-middle-class family. She was daughter of Dr. Wilhelm Willy Reitsch, who was ophthalmology clinic manager, and his wife Emy Helff-Hibler von Alpenheim, who was a member of the Catholic Austrian nobility. Hanna grew up with two siblings, her brother Kurt, a Frigate captain, and her younger sister Heidi. She began flight training in 1932 at the School of Gliding in Grunau. While a medical student in Berlin she enrolled in a German Air Mail amateur flying school for powered aircraft at Staaken, in a Klemm Kl 25. In 1933, Reitsch left medical school at the University of Kiel to become, at the invitation of Wolf Hirth, a full-time glider pilot/instructor at Hornberg in Baden-Württemberg. Reitsch contracted with the Ufa Film Company as a stunt pilot and set an unofficial endurance record for women of eleven hours and twenty minutes. In January 1934, she joined a South America expedition to study thermal conditions, along with Wolf Hirth, Peter Riedel and Heini Dittmar. While in Argentina, she became the first woman to earn the Silver C Badge, the 25th to do so among world glider pilots. In June 1934, Reitsch became a member of the Deutsche Forschungsanstalt für Segelflug (DFS) and became a test pilot in 1935. Reitsch enrolled in the Civil Airways Training School in Stettin, where she flew a twin-engine on a cross country flight and aerobatics in a Focke-Wulf Fw 44. At the DFS she test flew transport and troop-carrying gliders, including the DFS 230 used at the Battle of Fort Eben-Emael.

In September 1937, Reitsch was posted to the Luftwaffe testing centre at Rechlin-Lärz Airfield by Ernst Udet. Her flying skill, desire for publicity, and photogenic qualities made her a star of Nazi propaganda. Physically she was petite in stature, very slender with blonde hair, blue eyes and a "ready smile". She appeared in Nazi propaganda throughout the late 1930s and early 1940s. Reitsch was the first female helicopter pilot and one of the few pilots to fly the Focke-Achgelis Fa 61, the first fully controllable helicopter, for which she received the Military Flying Medal. In 1938, during the three weeks of the International Automobile Exhibition in Berlin, she made daily flights of the Fa 61 helicopter inside the Deutschlandhalle. In September 1938, Reitsch flew the DFS Habicht in the Cleveland National Air Races. Reitsch was a test pilot on the Junkers Ju 87 Stuka dive bomber and Dornier Do 17 light/fast bomber projects, for which she received the Iron Cross, Second Class, from Hitler on March 28th, 1941. Reitsch was asked to fly many of Germany's latest designs, among them the rocket-propelled Messerschmitt Me 163 Komet in 1942. A crash landing on her fifth Me 163 flight badly injured Reitsch; she spent five months in a hospital recovering. Reitsch received the Iron Cross First Class following the accident, one of only three women to do so.

In February 1943 after news of the defeat in the Battle of Stalingrad she accepted an invitation from Generaloberst Robert Ritter von Greim to visit the Eastern Front. She spent three weeks visiting Luftwaffe units, flying a Fieseler Fi 156 Storch. On February 28th, 1944, she presented the idea of Operation Suicide to Hitler at Berchtesgaden, which "would require men who were ready to sacrifice themselves in the conviction that only by this means could their country be saved." Although Hitler "did not consider the war situation sufficiently serious to warrant them...and...this was not the right psychological moment", he gave his approval. The project was assigned to Gen. Günther Korten. There were about seventy volunteers who enrolled in the Suicide Group as pilots for the human glider-bomb. By April 1944, Reitsch and Heinz Kensche finished tests of the Me 328, carried aloft by a Dornier Do 217. By then, she was approached by SS-Obersturmbannführer Otto Skorzeny, a founding member of the SS-Selbstopferkommando Leonidas (Leonidas Squadron). They adapted the V-1 flying bomb into the Fieseler Fi 103R Reichenberg including a two-seater and a single-seater with and without the mechanisms to land. The plan was never implemented operationally, "the decisive moment had been missed."

In her autobiography Fliegen, mein Leben Reitsch recalled that after two initial crashes with the Fi 103R she and Heinz Kensche took over tests of the prototype Fi 103R. She made several successful test flights before training the instructors. "Though an average pilot could fly the V1 without difficulty once it was in the air, to land it called for exceptional skill, in that it had a very high landing speed and, moreover, in training it was the glider model, without engine, that was usually employed." In October 1944, Reitsch claims she was shown a booklet by Peter Riedel which he'd obtained while in the German Embassy in Stockholm, concerning the gas chambers. She further claims that while believing it to be enemy propaganda, she agreed to inform Heinrich Himmler about it. Upon doing so, Himmler is said to have asked whether she believed it, and she replied, "No, of course not. But you must do something to counter it. You can't let them shoulder this onto Germany." "You are right," Himmler replied. During the last days of the war, Hitler dismissed Hermann Göring as head of the Luftwaffe and appointed Reitsch's lover, von Greim, to replace him. Von Greim and Reitsch flew from Gatow Airport into embattled Berlin to meet Hitler in the Führerbunker, arriving on April 26th, as the Red Army troops were already in the central area of Berlin. Reitsch and von Greim had flown from Rechlin–Lärz Airfield to Gatow Airfield in a Focke Wulf 190, escorted by twelve other Fw 190s from Jagdgeschwader 26 under the command of Hauptmann Hans Dortenmann. In Berlin, Reitsch landed a Fi 156 Storch on an improvised airstrip in the Tiergarten near the Brandenburg Gate. Hitler gave Reitsch two capsules of poison for herself and von Greim. She accepted the capsule.

During the evening of April 28th, Reitsch flew von Greim out of Berlin in an Arado Ar 96 from the same improvised airstrip. This was the last plane out of Berlin. Von Greim was ordered to get the Luftwaffe to attack the Soviet forces that had just reached Potsdamer Platz and to make sure Heinrich Himmler was punished for his treachery in making unauthorised contact with the Western Allies so as to surrender. Troops of the Soviet 3rd Shock Army, which was fighting its way through the Tiergarten from the north, tried to shoot the plane down fearing that Hitler was escaping in it, but it took off successfully. Reitsch was soon captured along with von Greim and the two were interviewed together by U.S. military intelligence officers. When asked about being ordered to leave the Führerbunker on April 28th, 1945, Reitsch and von Greim reportedly repeated the same answer: "It was the blackest day when we could not die at our Führer's side." Reitsch also said: "We should all kneel down in reverence and prayer before the altar of the Fatherland." When the interviewers asked what she meant by "Altar of the Fatherland" she answered, "Why, the Führer's bunker in Berlin ..." She was held for eighteen months. Von Greim killed himself on May 24th, 1945. Evacuated from Silesia ahead of the Soviet troops, Reitsch's family took refuge in Salzburg. During the night of May 3rd, 1945, after hearing a rumour that all refugees were to be taken back to their original homes in the Soviet occupation zone, Reitsch's father shot and killed her mother and sister and her sister's three children before killing himself.

After her release Reitsch settled in Frankfurt am Main. After the war, German citizens were barred from flying powered aircraft, but within a few years gliding was allowed, which she took up again. In 1952, Reitsch won a bronze medal in the World Gliding Championships in Spain; she was the first woman to compete. In 1955 she became German champion. She continued to break records, including the women's altitude record (6,848 m (22,467 ft)) in 1957 and her first diamond of the Gold-C badge. During the mid-1950s, Reitsch was interviewed on film and talked about her wartime flight tests of the Fa 61, Me 262 and Me 163. In 1959, Indian Prime Minister Jawaharlal Nehru invited Reitsch, who spoke fluent English, to start a gliding centre, and she flew with him over New Delhi. In 1961, United States President John F. Kennedy invited her to the White House. From 1962 to 1966, she lived in Ghana. The then Ghanaian President, Kwame Nkrumah invited Reitsch to Ghana after reading of her work in India. At Afienya she founded the first black African national gliding school, working closely with the government and the armed forces. The West German government supported her as technical adviser. Reitsch's attitudes to race underwent a change. "Earlier in my life, it would never have occurred to me to treat a black person as a friend or partner ..." She now experienced guilt at her earlier "presumptuousness and arrogance". She became close to Nkrumah. The details of their relationship are now unclear due to the destruction of documents, but some surviving letters are intimate in tone. In Ghana, some Africans were disturbed by the prominence of a person with Reitsch's past, but Shirley Graham Du Bois, a noted African-American writer who had emigrated to Ghana and was friendly towards Reitsch, agreed with Nkrumah that Reitsch was extremely naive politically. Throughout the 1970s, Reitsch broke gliding records in many categories, including the "Women's Out and Return World Record" twice, once in 1976 (715 km (444 mi)) and again, in 1979 (802 km (498 mi)), flying along the Appalachian Ridges in the United States. During this time, she also finished first in the women's section of the first world helicopter championships. Reitsch was interviewed and photographed several times in the 1970s, towards the end of her life, by Jewish-American photo-journalist Ron Laytner.

Reitsch died of a heart attack in Frankfurt at the age of 67, on August 24th, 1979. She had never married. She is buried in the Reitsch family grave in Salzburger Kommunalfriedhof. Former British test pilot and Royal Navy officer Eric Brown said he received a letter from Reitsch in early August 1979 in which she said, "It began in the bunker, there it shall end." Within weeks she was dead. Brown speculated that Reitsch had taken the cyanide capsule Hitler had given her in the bunker, and that she had taken it as part of a suicide pact with Greim. No autopsy was performed, or at least no such report is available.

#ww2 #world war 2 #second world war #world war ii #wwii #history #german history #biography #aviation #womens history #women in history #germany #airforce history #test pilot

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jasper-crow · 1 day ago

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(via striketheearth-blog)

What an excellent use of the time machine. Vintage DF world Gen 💙

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stainlesssteellocust · 5 years ago

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The fact that it’s possible, perhaps even inevitable to cause a zombie apocalypse in the new version of Dwarf Fortress really is quite something. I made a small world the other day and the necromancers wiped out every civilisation, bar none (though I may try and see if Fortress Mode is still viable and make a comeback), and I had a whale of a time creating human Outsiders and going digging through the wreckage of the world.

One adventurer had to escape a horde of zombies by jumping in a river, then later he got pinned and killed by ghouls whilst searching through an abandoned hillock. Another went around wrecking face with a gold Warhammer (outsider gear is hilarious and possibly bugged???) before an infected thrall bit her and she turned, so I had her commit suicide by Night Troll. I found a refugee camp only to find they’d all been turned by the new red undead, so that one got torn apart. One fell down a waterfall, which seem to be more common nowadays. Another was killed by thralls in a still-populated village, after saving several of the locals. A bunch of dudes were living in a tomb, which gives me all sort of creative ideas, too.

My latest outing was a party of two girls plus a pet adder, which tragically got killed by Grizzly Bear Men. It was avenged, and is still mourned. My group took on an undead lieutenant only to get absolutely wrecked, so we ran (with the adder, who was still with us at that point). Also, can we talk about how cute it is that pre-gen party members in DF love to say things like “I’m so happy to have a friend like you!” You got to take the good where you can get it in this wild world of shapeshifting bogeymen and endless Night Troll attacks.

After a time the pair settled down in a cottage in an abandoned human village where the streets are overgrown with flowers. There’s a well and plenty of plants, and each day they go scouting the surrounding area. A goblin lawgiver lives in a nearby mead hall, still claiming to be part of a government, and refused to join us out of duty to a group of which he seems to be the only survivor. I like to think he’s gone a bit mad, and is trying to keep the dream alive. We saved him from a thrall and befriended him, and though he gets a bit grouchy if you try to compliment him, he’s nice enough.

My pair go exploring, and all sorts of strange things can be found. We looted better gear from an old armoury (well, a stash of weapons in a castle), and made sure to get a weapon and shield for our goblin buddy too. In an abandoned castle we found a collection of books written by a necromancer, which I like to think is some sort of spooky apocalyptic log written by the eventual winners.

One time we were bushwhacked by a whole horde of the dead outside a hillock, and one member of the party had to stand guard over the other after she collapsed, successfully defeating them all to keep the other safe. Another time there was a large, friendly and welcoming community of Night Creatures made from horrible necromancer experiments, so it’s nice to know living, loving creatures will remain even in this new world, I Am Legend style. Then we found a surviving human village under attack from more thralls, and saved them! Also we discovered the corpse of a previous adventurer nearby and recovered their sword.

Now my characters have acquired a small library and a musical instrument (though I can’t get them to use it), and one is practicing storytelling. They sleep in their cozy apocalypse cottagecore home every night as weird little asterisks fly around outside, and both can kill a small army on their lonesome.

They’re still mourning that adder though.

#Dwarf Fortress

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britesparc · 4 years ago

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Weekend Top Ten #432

Top Ten Games to Remaster

As we continue June’s videogame-themed series of Tops Ten – during what would normally have been E3, but is still something of a prolonged Videogame Announcement Season – I turn my attention once again to great games past. This has been exacerbated by the release of Command & Conquer Remastered Collection, a hi-def spit-and-polish re-do of two of the greatest PC games of the nineties. I have very fond teenage memories of both C&C and its pseudo-sequel, but Red Alert in particular strikes an important chord as one of “the” games that deepened and broadened by love of gaming as an art form. In the way that really only happens when you’re a kid, I absorbed Red Alert, not just completing the campaign and playing hours and hours of skirmish, but also talking about it extensively with friends, designing my own levels, and even going so far as to modify the source files to create my own super-units (nuclear tanks ahoy!). As such, it utterly delights me to declare that C&C Remastered is a phenomenal undertaking, the graphics painstakingly remade to fit modern displays, the interface masterfully tweaked to appease modern sensibilities. But at the same time it offers so many pleasing, knowing, considerate hat-tips to fans, such as a re-imagining of the classic DOS installation prompts. All in all, it’s a must-buy, bringing a 25-year-old series of games more-or-less bang up to date and preserving their legacy for a new generation.

Anyway, all this got me thinking of other classic games, and how it’s so difficult to play them nowadays. Maybe they’re mired in rights issues. Maybe it’s a technological minefield to get them to run on modern systems. Maybe elements of modern gaming – be it graphics or design – have simply passed them by, making them a far more difficult and frustrating experience than they would have seemed Back in the Day. Whatever the reason, these are games that – like classic films from the 40s and 50s – should be celebrated and enjoyed by the young’uns, not left to gather digital dust on forgotten floppies the world over.

So, with no further ado, here are ten games that I would love to see given a bit of digital TLC, renewed and revigorated for the ultra-wide monitors and liquid-cooled systems of tomorrow. In most cases these are just one game that I’d like to see spruced up and re-released, but there are a few “collections” here too, whether it’s a C&C-style pairing of a great double act, or a celebration of a series, a la Halo: The Master Chief Collection.

Oh, and I’m on about remasters here: not a full-on remake or reboot. Stuff like Perfect Dark on the Xbox 360, not Doom 2016. Old games made good on modern hardware, not a reimagining of the property.

Regardless: have at it, games industry.

Lemmings (1991) and Lemmings 2: The Tribes (1993): I definitely think they should be a double-pack, because whilst the first is a well-regarded classic, the second refines the formula, makes it more user-friendly, offers skirmish-style training modes, and amps up the comedy. But they’re both ancient by now, and despite mobile do-overs in recent years, the originals are very difficult to play. Upping the resolution whilst still keeping the character of the scantily-pixelated sprites would be difficult, but it’d be worth it to once again sample one of the gods of gaming.

Sam & Max Hit the Road (1993): other LucasArts classic adventures have had a spruce – most notably the first two seminal Monkey Island games – but it’d be good to see this cult comedy classic come back to life. I don’t know if the backgrounds ever existed in higher resolution, but I’d love to see the sprites re-drawn to more closely resemble a cartoon version of Steve Purcell’s artwork.

The Jedi Knight Series (1995-2003): I’m bundling all four Jedi Knight games in together – that’s the original Dark Forces, plus Jedi Knight, Jedi Outcast, and Jedi Academy – but let’s be honest, it’s the first two we’re really after. DF gave us a compelling mission-based “Doom Clone” (back when Doom was a genre), and one which would be amazing to see tarted up to 4K with texture filtering a-go-go; but it was its 1997 sequel, Jedi Knight: Dark Forces II, that struck serious beskar. Huge, expansive levels, in “true 3D” (as we used to call it), full-motion video cutscenes, finally getting a lightsaber and Force powers, but most of all the Light/Dark Side dynamic offering (very basic) morality and a branching storyline. Again, giving it a glossy hi-def sheen would do wonders to preserve the legacy of one of the greatest Star Wars games of all time.

The Quake Collection (1996-2005): really it should be called The Quake Qollection, no? Encompassing all four mainline Quakes. Although, again, let’s be honest: there’s something deeply iconic about the first three, so no one would complain if we just forgot about part 4, yeah? Anyway: Quake was a stunner, a gorgeous 3D technical juggernaut, offering sumptuous lighting effects and gorgeous architecture. Part II came a year later and offered us coloured lighting and a coherent sci-fi story, whereas Quake III Arena in 1999 gave us a sublimely crafted multiplayer shooter and a character that was an eyeball doing a handstand. Despite being graphical powerhouses in their day, getting them to run can be a drag, so it’d be lovely to see them dragged into the 21st Century, especially if they could offer us ray-tracing on next-gen consoles, a la Quake II RTX.

Tomb Raider (1996): we’ve seen the series rebooted in (generally) excellent fashion, but at the same time it feels it lost a little of the majesty, mythos, and merriment of OG Lara. One of the first truly successful 3D games, it was like nothing before it. A subtle update to increase its resolution, filter the rough edges, maybe offer the option to move beyond the rigid grid-based movement structure, and possibly up the poly count so blocky Lara more closely resembles her rendered box-art cousin, would be terrific. Imagine the dinosaur in 4K…!

Descent (1994): one of those games that’s slipped from public consciousness, this was a full-3D shooter a couple of years before Quake shambled onto our screens. Piloting a craft in zero gravity, it offered full freedom of movement as well as a tense shooter dynamic coupled with some mild, X-Wing-style space sim elements. It was funky, fast, gorgeous, and messed with your head. I’d love a remake that kept the levels as-is, simplified the often-complex controls for modern sensibilities, and just in general made it look prettier. I worry that a contemporary “re-imagining” might lose too many of its crazy rough edges, though.

Syndicate (1993): there have been a number of efforts to re-do Syndicate over the years, but apart from its excellent sequel Syndicate Wars in 1996, none have matched the dark joys of the original. rather than try to go all modern and 3D, I’d rather see the artwork redone, redrawn at a higher resolution, perhaps offering subtle 3D touches such as dynamic light, shadow, and ray-tracing. The fiddlier aspects (getting into cars?!) could be tidied up, but the look and feel should remain the same. I honestly think this could be a big deal.

Total Annihilation (1997): if C&C can get remastered, why not the game that was arguably the first real challenger to its sci-fi RTS dominance? TA had 3D graphics, a new and refined model of base construction, and tactical touches such as line-of-sight and elevated terrain. But the comparatively low resolution of late-nineties machines meant that the robotic units could often appear slightly indistinct, turning into a grey melange; boosting the res and the poly count would do wonders, but – like C&C – the gameplay itself should be kept as authentic as possible.

Warcraft I & II (1994-95): I know, I know; they just did a remaster of Warcraft III that wasn’t well received and got everybody’s backs up. But I barely played Warcraft III (I barely played Warcraft I for that matter). Warcraft II: Tides of Darkness was the fantasy yin to C&C’s sci-fi yang, and it was great; clear, bright, fast, fun. The cartoony graphics were gorgeous and the units had bags of character (reinforced by the humorous soundbites when you kept clicking on them). I’d want to see the sprites re-drawn in hi-res, with the units given some gorgeous new animations to match their character. Other than that? Keep it broadly the same. It worked 25 years ago, it’ll work now.

Fantasy World Dizzy (1989): I nearly didn’t have a game this old on the list. For one thing, I thought pre-16-bit games would require far more retooling for modern audiences, becoming essentially the sort of reboot I said I wanted to avoid; I can’t imagine a new Skool Daze being too similar to its original. Also which Dizzy do you choose? The one I played the most was probably Spellbound (1991). But I think Fantasy World may be the most iconic. Its Amiga port was almost a remaster anyway, giving it gorgeous colour graphics. A modern version would up the resolution with all-new art assets, obviously, and perhaps could offer a more user-friendly jumping dynamic (and maybe – maybe – I’ll allow scrolling). This could be a lovely way to re-introduce audiences to the character of Dizzy, who should really be held up more as a British gaming mascot, without having to go all-in on a brand new title. Egg-cellent (sorry).

So there we are. There are a couple missing here, obviously; Simon the Sorcerer was nearly there until I realised they did do a gentle remaster in 2018. The Settlers would have made the list, except they are remaking that, although in my opinion it looks like a full-on reboot rather than the upgraded version of the original that I crave. Fade to Black just dropped off the bottom on the grounds that I barely played it in its original form, but a third-person 3D Flashback is still on my Most Wanted list (Flashback itself, sadly, has already had a disappointing remake). And the best Star Wars game of all time, Knights of the Old Republic, I decided not to include as – again – I think we’re going to see that reimagined and folded into the new official Disney canon in some form. Maybe that should preclude me imagining the original game in 4K with updated character models, dynamic shadows, and ray-tracing, but – hey – that’s just me. At least that is one game that I’ll still be able to play fairly easily on an Xbox Series X, even without whistles and bells. Here’s to dead old games!

#top ten #games #gaming #remasters #old games #retro games #command & conquer #lemmings #star wars #dizzy #warcraft #quake

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abrilu-u · 4 years ago

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5 Simple Techniques For Psn br store

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nahaszing · 2 years ago

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Gamebryo engine flight sim

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Asset quality, shading quality, promising indications of ray tracing, more realistic 'people rendering', plus a tantalising tease for the game worlds we'll be visiting. This looked to be a clean break as opposed to the iterative upgrades we've seen to the engine since it transitioned from Gamebryo to Creation Engine. What we saw looked like a proper generational leap for Bethesda Game Studios titles with Creation Engine 2 looking nothing like its predecessors. It started with the first 'in-game' reveal of Starfield, due for release at the end of next year, and it was a feast for the eyes, certainly from a technological perspective. What they did do - to varying levels of success - was to hammer home how shrewd of an acquisition Bethesda is. However, from a personal perspective, this was the event to deliver on the promise - to seal the deal - and Microsoft did not do that. As we discuss above though, there is the sense from the media that many of the issues people raised about last year's gameplay reveal have been addressed. This is fine (if not exactly ideal) for a game early in development, but for a tentpole title mere months away from release this is more than slightly concerning. or did we? As is the E3 tradition, much of what we saw was 'in-engine' - which is to say that we have no idea if this is running in real-time or whether it's pre-rendered and if it was real-time, what kind of hardware was running it. We also got to see more of Halo Infinite.

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We kick off our show by sharing our thoughts on Forza Horizon 5 from Playground Games - a game that's cross-gen in nature but still manages to fully exercise the latest in console and PC hardware. That's what we're discussing in the latest Digital Foundry Direct, where myself, John Linneman and Alex Battaglia pick out our highlights from the Xbox team's 90-minute showing and share some thoughts on how Microsoft chose to cram 30 games into what is a relatively short presentation and the extent to which it was successful. This one had it all - and perhaps it actually delivered too much, to the detriment of some of the games shown. And in the process, Xbox went one stage further in comprehensively taking down the argument that its first-party line-up is lacking, while at the same time addressing the cross-gen controversy that made it feel like Microsoft wasn't fully committed to the concept of delivering games tailored to the strengths of the new wave of console and PC hardware. The firm had already firmly established Game Pass as a service offering unbeatable value, but remarkably, the show did an impressive job of making the subscription seem almost indispensable. The stars were aligned for Microsoft to deliver a phenomenal E3 2021 showcase and it's fair to say that Xbox and Bethesda delivered.

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bloghealthcom · 3 years ago

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Metformin và ung thư tuyến tụy Update 07/2021

Bài viết Metformin và ung thư tuyến tụy Update 07/2021 được chia sẻ bởi website Blog-Health #bloghealth #suckhoe #lamdep #sinhly

Bài viết được viết bởi Thạc sĩ, Bác sĩ Mai Viễn Phương - Bác sĩ nội soi tiêu hóa - Khoa Khám bệnh & Nội khoa - Bệnh viện Đa khoa Quốc tế Vinmec Central Park.

Metformin có thể trực tiếp kích hoạt AMPK, dẫn đến ức chế tín hiệu Akt/mTOR xuôi dòng và ức chế tăng sinh tế bào. Trong số những bệnh nhân ung thư tuyến tụy, việc được điều trị bằng metformin dường như có thể cải thiện các triệu chứng một cách hiệu quả.

1. Metformin hoạt động như chất chống ung thư

Hai cơ chế tiềm năng cho hoạt động chống ung thư của metformin đã được đề xuất. Cụ thể:

Metformin có thể trực tiếp kích hoạt AMPK, dẫn đến ức chế tín hiệu Akt/mTOR xuôi dòng và ức chế tăng sinh tế bào.

Việc giảm nồng độ insulin và IGF trong tuần hoàn do metformin gây ra có thể làm giảm hoạt hóa trục truyền tín hiệu của thụ thể IGF, dẫn đến giảm sự thúc đẩy tăng trưởng và hình thành phân bào. Do đó, tác dụng chống ung thư của metformin được thể hiện qua trung gian cải thiện hệ thống chuyển hóa hoặc trực tiếp trên các tế bào khối u.

Tổng quan về cơ chế tế bào của metformin trong bệnh ung thư tuyến tụy.

2. Metformin và ung thư tuyến tụy

Ung thư tuyến tụy là nguyên nhân gây tử vong do ung thư đứng hàng thứ tư ở Hoa Kỳ và tiên lượng của nó vẫn còn rất thấp, việc khuyến khích nghiên cứu để tìm ra các tác nhân cải tiến tích cực trong điều trị là một nhu cầu cấp thiết chưa được đáp ứng. Ung thư biểu mô tuyến tụy (PDAC) là loại mô học phổ biến nhất. Mối liên quan giữa việc sử dụng metformin và giảm tỷ lệ ung thư tuyến tụy ở bệnh nhân đái tháo đường týp 2 lần đầu tiên được công nhận bởi hai nghiên cứu lâm sàng lớn.

Trong một nhóm thuần tập hồi cứu thực hành rộng rãi, Currie và cộng sự đã báo cáo giảm nguy cơ ở người dùng metformin liên quan đến sulfonylurea (HR: 0,20; KTC 95%: 0,11-0,36) và ở người điều trị dựa trên insulin (HR: 0,22; KTC 95%: 0,12-0,38). Tương tự như vậy, trong một nghiên cứu bệnh chứng tại bệnh viện, Li và cộng sự giảm rủi ro ở những người sử dụng metformin so với những người không sử dụng (OR: 0,38; KTC 95%: 0,21-0,67). Một số phân tích tổng hợp đã củng cố mạnh mẽ việc giảm nguy cơ ung thư tuyến tụy khi sử dụng metformin ở bệnh nhân đái tháo đường týp 2. Tuy nhiên, hiệu ứng này cần được xác nhận trong các thử nghiệm lâm sàng tiền cứu lớn.

3. Tiên lượng sống của bệnh nhân ung thư tuyến tụy có sử dụng metformin

Trong một nghiên cứu hồi cứu, Sadeghi và cộng sự báo cáo nguy cơ tử vong thấp hơn 36% (HR: 0,64; KTC 95%: 0,48-0,86), lợi ích tỉ lệ sống là 4 tháng (15,2 tháng so với 11,1 tháng) và xấp xỉ tăng gấp 2 lần tỷ lệ sống sót sau 2 năm (30,1% so với 15,4%) ở những bệnh nhân dùng metformin so với những bệnh nhân nội trú không dùng. Điều thú vị là khả năng sống sót lâu hơn chỉ được quan sát thấy ở bệnh không di căn, khi được phân tầng theo giai đoạn bệnh. Các bằng chứng khác cũng được cải thiện về tỷ lệ sống được đề cập đến trong phân nhóm cắt bỏ hoặc tiến triển tại chỗ nhưng không di căn. Cụ thể, trong số những bệnh nhân được điều trị bằng PDAC, việc sử dụng metformin dường như cải thiện hệ điều hành sau 18 tháng. Liên quan đến bệnh tiến triển tại chỗ hoặc bệnh di căn, các bằng chứng khác trái ngược nhau về tỷ lệ sống sót ở bệnh nhân PDAC khi tiếp xúc với metformin chỉ được báo cáo trong một nhóm thuần tập châu Á.

Những bệnh nhân ung thư tuyến tụy không di căn dùng metformin có khả năng sống sót lâu hơn

4. Các nghiên cứu nói gì?

Một phân tích tổng hợp lớn đã phân tích dữ liệu từ 12 nhóm thuần tập hồi cứu chứng minh sự cải thiện hệ điều hành ở người dùng metformin trong các giai đoạn khác nhau (HR: 0,77; KTC 95%: 0,68-0,87). Gần đây, một phân tích tổng hợp, bao gồm hai RCT đã phân tích lại sự cải thiện trong hệ điều hành và xác nhận lợi ích trên toàn bộ dân số bệnh nhân đái tháo đường với PDAC (HR: 0,86; KTC 95%: 0,76-0,97). Phân tích các phân nhóm trong nghiên cứu này cho thấy khả năng sống sót được cải thiện ở những bệnh nhân có khối u đã được cắt bỏ hoặc tiến triển tại chỗ, nhưng không thuộc nhóm di căn. Kết quả tương tự cũng được quan sát thấy ở một nhóm khác có lợi ích về tỉ lệ sống còn toàn bộ ở các giai đoạn khác nhau, điều này được thể hiện rõ hơn tại các phân nhóm ở giai đoạn ít tiến triển hơn và bệnh nhân châu Á.

5. Kết quả ở bệnh nhân ung thư tụy điều trị bậc hai

Xem xét điều trị bậc hai, một nghiên cứu tiền cứu một nhánh không đạt được tỷ lệ sống sót của metformin liên quan đến paclitaxel. Kết quả của các thử nghiệm lâm sàng gần đây được mong đợi với sự quan tâm đáng kể. NCT01666730 khám phá sự cải thiện khả năng sống sót tổng thể của metformin liên quan đến FOLFOX6 được điều chỉnh ở bệnh nhân di căn. NCT02005419 đánh giá DFS sau 1 năm với sự kết hợp của metformin, gemcitabine ở những đối tượng bị cắt bỏ và NCT02048384 phân tích tính an toàn của metformin có hoặc không rapamycin sau khi ổn định bệnh trên hóa trị liệu đầu tiên do di căn.

Bằng chứng lâm sàng này liên quan đến dữ liệu tiền lâm sàng, rằng tế bào ung thư tuyến tụy nhạy cảm với sự ức chế quá trình phosphoryl oxy hóa, giảm tín hiệu insulin-IGF và ức chế con đường mTOR thông qua hoạt hóa AMPK, đây là một số tác dụng chống ung thư chính của metformin. Việc xác định các yếu tố dự báo hoặc tiên lượng về đáp ứng với metformin nên phù hợp để lựa chọn những bệnh nhân có nhiều khả năng được hưởng lợi nhất từ metformin. Những tiến bộ gần đây về đặc điểm phân tử có thể phân biệt sinh học khác nhau và đáp ứng với liệu pháp ở những bệnh nhân có PDAC tương tự về hình thái có thể được đưa vào các thử nghiệm lâm sàng.

Hơn nữa, thách thức kinh nghiệm gần đây về tiêu chuẩn chăm sóc trong điều trị ung thư tuyến tụy tiên tiến bằng liệu pháp đa hóa chất cũng mang lại những quan điểm mới, khi bệnh nhân trải qua thời gian sống lâu hơn với nhu cầu kết hợp các hoạt chất khác. Các thử nghiệm trong tương lai sẽ bao gồm giai đoạn bệnh, xác định các dấu ấn sinh học và nồng độ của metformin trong mô ung thư để đánh giá mạnh mẽ lợi ích của metformin trong điều trị PDAC.

Các tế bào ung thư tuyến tụy nhạy cảm với sự ức chế quá trình phosphoryl oxy hóa

6. Khối u thần kinh nội tiết tuyến tụy

Một loại ung thư tuyến tụy khác có tỷ lệ mắc gia tăng là khối u thần kinh nội tiết tuyến tụy (panNETs). Rất ít nghiên cứu đã đánh giá lợi ích lâm sàng của metformin trong điều trị panNET. Theo Pusceddu và cộng sự, trong một nhóm thuần tập hồi cứu đa trung tâm về bệnh nhân dùng everolimus có hoặc không chất tương tự somatostatin, đã báo cáo PFS tăng ở bệnh nhân tiểu đường tiếp xúc với metformin so với bệnh nhân tiểu đường không tiếp xúc hoặc bệnh nhân không bị tiểu đường [44,2 so với 20,8 tháng (nhịp tim: 0,49; KTC 95%: 0,34-0,69) hoặc 15,1 tháng (HR: 0,45; KTC 95%: 0,32-0,62), tương ứng]. Kết quả này tương quan với in vitro, bằng chứng cho thấy metformin làm giảm sự tăng sinh trong các dòng tế bào panNET của người.

Một nghiên cứu gần đây đã chứng minh rằng, sự kết hợp giữa metformin và everolimus sẽ ức chế mạnh mẽ sự tăng sinh tế bào panNET của con người thông qua việc ức chế mTOR, so với mỗi tác nhân được sử dụng một mình. Kết quả của thử nghiệm tiền cứu NCT02294006 đang diễn ra được kỳ vọng sẽ đánh giá tốt hơn tác động của phương pháp điều trị thử nghiệm này đối với PFS ở 12 tháng.

7. Kết luận

Sự thay đổi con đường nội bào đáng chú ý gây ra bởi quá trình sinh ung thư, các cơ chế tiềm năng trong hoạt động kháng u của metformin đã được hỗ trợ. Họ đã tiết lộ các phân tử mục tiêu và khả năng điều trị mới được phát hiện. Liên quan đến nghiên cứu dịch tễ học, tiền lâm sàng và lâm sàng, dữ liệu hỗ trợ cho rằng metformin có lợi cho một số bệnh nhân có khối u hệ tiêu hoá, đòi hỏi các thử nghiệm lâm sàng nghiêm ngặt để xác định những người có thể có lợi thế từ sự kết hợp metformin.

Tuy nhiên, do kết quả sống sót bị ảnh hưởng bởi vô số yếu tố, chẳng hạn như loại ung thư, sự khác biệt, giai đoạn và điều trị, để định vị lại việc sử dụng metformin trong ung thư hệ tiêu hoá, điều cần thiết là phải xem xét các đặc điểm của bệnh nhân. Điều này có thể đóng vai trò là dấu ấn sinh học dự đoán tác dụng kháng u của metformin, chẳng hạn như kháng insulin, bệnh tiểu đường, cấu tạo cơ thể và các bệnh mãn tính liên quan đến viêm cũng như con đường gây ung thư do khối u điều khiển cụ thể, có thể cản trở tác dụng kháng u trực tiếp và gián tiếp của metformin. Hiện nay, sàng lọc ung thư sớm được coi là biện pháp hoàn hảo trong việc phát hiện và điều trị kịp thời các loại ung thư. Giảm chi phí điều trị và nhất là giảm tỷ lệ tử vong ở người bệnh. Bệnh viện Đa khoa Quốc tế Vinmec luôn triển khai và giới thiệu tới khách hàng Gói Sàng lọc ung thư sớm tại Vinmec - An tâm sống khỏe giúp xét nghiệm gen, chẩn đoán hình ảnh, xét nghiệm các chất chỉ điểm sinh học phát hiện khối u sớm.

Lựa chọn Gói sàng lọc ung thư sớm tại Vinmec - An tâm tại Vinmec, khách hàng sẽ được:

Chỉ một lần xét nghiệm gen có thể đánh giá về nguy cơ mắc của 16 loại ung thư phổ biến ở cả nam và nữ (Ung thư phổi, ung thư đại trực tràng, ung thư vú, ung thư tuyến tụy, ung thư cổ tử cung, ung thư dạ dày, ung thư tiền liệt tuyến,....)

Phát hiện sớm các dấu hiệu manh nha của ung thư thông qua chẩn đoán hình ảnh, nội soi và siêu âm.

Thao tác khám đơn giản, cẩn thận và chính xác.

Đội ngũ chuyên gia được đào tạo bài bản nghề, đặc biệt là về ung thư, đủ khả năng làm chủ các ca khám chữa ung thư.

Với hệ thống cơ sở vật chất, thiết bị y tế tiên tiến, hiện đại và đội ngũ bác sĩ có chuyên môn sâu, kinh nghiệm dày dặn sẽ giúp quá trình thăm khám và điều trị của người bệnh tại Vinmec trở nên nhanh chóng với hiệu quả cao, tiết kiệm chi phí và thời gian.

Để được tư vấn trực tiếp, Quý Khách vui lòng bấm số HOTLINE hoặc đăng ký lịch trực tuyến TẠI ĐÂY. Tải ứng dụng độc quyền MyVinmec để đặt lịch nhanh hơn, theo dõi lịch tiện lợi hơn!

Tài liệu tham khảo: Cunha Júnior AD, Bragagnoli AC, Costa FO, Carvalheira JBC. Repurposing metformin for the treatment of gastrointestinal cancer. World J Gastroenterol 2021; 27(17): 1883-1904 [DOI: 10.3748/wjg.v27.i17.1883]

source https://blog-health.com/metformin-va-ung-thu-tuyen-tuy/

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