#cancer tumor palliation

[arrangoiz]

The Role of Surgery in Metastatic Breast Cancer

The role of locoregional treatment in the setting of de novo metastatic breast cancer: Is controversial Typically, surgery: Has been reserved for palliation A 2012 meta-analysis of 15 retrospective studies showed: Resection of the primary tumor: Was associated with increased overall survival: OS; HR 0.69, 95% CI 0.63 to 0.77, P<0.00001 Unfortunately, recent prospective studies have shown…

[drlalitmohansharma]

What are the common types of cancer treatment available?

There are several common types of cancer treatment available, often used alone or in combination depending on the type and stage of cancer. Here are the primary treatment modalities:

Surgery: This involves the physical removal of the tumor and nearby tissue that may contain cancer cells. It is often used when the tumor is localized and hasn't spread extensively Cancer treatment in Bhilwara.

Chemotherapy: This treatment uses drugs to kill cancer cells or stop their growth. It can be administered orally or intravenously (IV), and targets rapidly dividing cells throughout the body.

Radiation Therapy: This treatment uses high-energy rays (such as X-rays or protons) to kill cancer cells. It can be targeted to a specific area (external beam radiation) or delivered internally (brachytherapy).

Immunotherapy: This approach harnesses the body's immune system to recognize and attack cancer cells. It includes monoclonal antibodies, checkpoint inhibitors, cytokines, and cancer vaccines Cancer treatment in Bhilwara .

Targeted Therapy: This treatment targets specific genes, proteins, or the tissue environment that contribute to cancer growth and survival. It differs from chemotherapy by aiming at specific molecular targets.

Hormone Therapy: This is used to treat cancers that are hormone-sensitive (e.g., breast cancer, prostate cancer) by blocking or lowering the amount of hormones in the body or by blocking hormone receptors on cancer cells.

Stem Cell Transplant: Also known as a bone marrow transplant, this procedure involves replacing diseased bone marrow with healthy stem cells to help the body recover from high doses of chemotherapy or radiation therapy.

Precision Medicine: This involves using genetic testing to identify specific mutations in cancer cells Cancer treatment in Bhilwara, allowing doctors to prescribe targeted therapies that are more likely to be effective.

These treatments can be used alone or in combination, depending on factors such as the type and stage of cancer, overall health of the patient, and treatment goals (such as cure, control, or palliation) Oncologist Near Me. Treatment plans are often personalized based on these considerations.

[bravishankarsm]

Hypofractionation for Primary and Metastatic Lung Tumors

The Story of Lung Cancer

The Beginning: Prevention

‒Smoking cessation (combined pharmacologic and behavioral therapy is most effective)

‒Low-dose CT screening (age 50, > 20 pack-years, cessation < 15 years ago)

The Middle: Diagnosis and Treatment

‒Integration of multidisciplinary care provided by various oncologists

‒Monitoring for recurrence

‒Survivorship care

The End: Palliation

‒Early palliative care involvement

‒Effective symptom management

‒Appropriate advance care planning and use of hospice

[drmsskeerthi]

When Should You See An Oncologist? Do All Cancers Require Surgery?

Cancer, a terrifying opponent in the realm of human health, continues to test the boundaries of medical science due to its intricate nature and the wide spectrum of variations seen across individuals and tumor types. The comprehension of cancer complications and the vital roles played by oncologists are consummate for effectively maneuvering through the complex pathways of cancer care. From the original stages of diagnosis through treatment modalities and ongoing management, the symbiotic relationship between patients and oncologists remains vital in casting personalized and impactful strategies against this complaint. Let’s explore this guide under the guidance of the best oncologist surgeon in Hyderabad Dr. M.S.S. Keerthi.

Understanding Cancer and Oncologists:

Cancer is indeed a multifaceted complaint that can affect varied organs and systems in the body. It’s represented by uncontrolled cell excrescency that can invade surrounding organs and spread to distant organs, a process known as metastasis. Oncologists are specialized physicians trained in diagnosing and treating cancer utilizing a range of tools and remedies.

Types of Oncologists:

Medical Oncologists: These specialists concentrate on using systemic treatments similar to chemotherapy, targeted remedies, and immunotherapy. They work closely with patients to manage side effects and adjust treatment plans as required.

Surgical Oncologists: These experts are professed to perform surgical procedures to remove tumors and affected organs. They may also perform biopsies to confirm cancer diagnoses.

Radiation Oncologists: They specialize in using high-energy radiation rays to destroy cancer cells and shrink excrescences. They unite with other oncologists to integrate radiation remedies into comprehensive treatment plans.

When to Consult an Oncologist?

Consulting an oncologist is crucial at different stages of the cancer journey:

Diagnosis After a suspicious finding on imaging or biopsy, consulting an oncologist helps confirm the diagnosis and determine the extent of the condition( stage).

Treatment Planning Oncologists consider various factors, including cancer type, stage, inheritable markers, and overall health, to tailor treatment plans. They may also unite with other specialists in a multidisciplinary team.

Follow-up Care Even after completing original treatments, regular follow-ups with an oncologist are essential for monitoring for recurrence or managing long-term side effects.

What Will Your Oncologist Do?

Oncologists provide comprehensive care throughout the treatment process:

Diagnostic Workup: This includes reviewing medical history, conducting physical examinations, arranging imaging experiments( like CT scans, MRIs, PET scans), and performing biopsies as required.

Treatment Recommendations: Based on individual findings, oncologists project substantiated treatment regimens which may carry surgery, chemotherapy, radiation remedy, immunotherapy, hormone remedy, or a combination of these.

Supportive Care: Oncologists also address symptom management, supply emotional support, and conciliate care with other healthcare providers such as nutritionists, physical therapists, and counselors.

Surgery and Cancer Treatment:

Surgical interventions play a crucial role in cancer treatment:

Primary Treatment Surgery may be the primary treatment for localized cancers, especially if they’re exploitable and haven’t spread significantly.

Adjuvant or Neoadjuvant remedy In some cases, surgery is followed by more treatments like chemotherapy or radiation therapy( adjuvant therapy) to target any remaining cancer cells. The neoadjuvant remedy is given before surgery to shrink excrescences or enhance surgical outcomes.

Palliative Surgery For advanced cancers, surgery may be performed to palliate symptoms or enhance the quality of life, indeed if a cure isn’t possible.

Do All Cancers Need Surgery?

While surgery is a cornerstone of cancer treatment, not all cancers require surgical intervention immediately or at all:

Indispensable Treatments Some cancers respond well to nonsurgical treatments like chemotherapy, targeted remedy, immunotherapy, or radiation remedy.

Advanced Stages Advanced cancers or those with metastasis frequently bear a multimodal approach combining surgery with other treatments for optimal issues.

Individualized Approach Treatment opinions consider factors similar to excrescence position, size, inheritable factors, overall health, and case preferences.

In essence, the collaboration between patients, oncologists, and multidisciplinary teams ensures substantiated and effective cancer care. As Dr. MSS Keerthi highlights, understanding the roles of different oncologists, the timing of consultations, treatment options beyond surgery, and the evolving landscape of cancer care, individuals can navigate their cancer journey with knowledge and confidence. Always remember, that seeking timely medical advice and staying informed are crucial steps in managing cancer effectively.

[candrol-hospital]

Breast Cancer Natural Treatment Options to Palliate It Naturally

Today, We’re Going to Discuss the Natural Treatment of Breast Cancer and all other breast cancer natural treatment options in details. Breast Cancer – An Introduction Breast Cancer is one of the most common types of cancer which is becoming the leading cause of deaths among women. s the name suggests, breast cancer is a name given to the tumorous growth of malignant breast tissue. Although it is not sure that breast cancer always has to be malignant, it can be benign, as well!

Website:

https://www.candrol.com/breast-cancer-natural-treatment-options/

[denjoydevice]

The Many Different Specialties in Medical Specialties

Medical is the medical art, science and technique of treating a patient with a disease or injury and managing the entire treatment, diagnosis, prevention, rehabilitation or palliation of the illness or injury. Medical science encompasses various medical practices developed over the years to keep and restore good health by the management of disease and injury. It includes all branches of medicine such as pharmacy, nursing, physicians, psychiatrists, and surgeons. It also covers specialized fields such as obstetrics and orthopedics. It has become one of the major fields of study and profession all over the world. Many universities and colleges have medical courses and programs to train future medical professionals.

In United States, doctors and physicians can specialize in specific areas of medicine. For instance, nurses can specialize in either pediatricians' or cardiologists subspecialties. Cardiologists can specialize in either coronary heart diseases or pulmonary diseases. Orthopedists can specialize in either cranial or limit medical specialties.

There are many branches of medicine with a broad scope of subspecialties within it. For instance, anesthesia is the medical field that provides the application of drugs used during surgery or to alleviate pain after surgery or illness. Anesthesiology can be further subclassified into general anesthesia and local or area anesthesia. 

Oncology is a branch of medicine that deals with cancer. It can also be subclassified as internal medicine and surgery. Oncology can further be subclassified into chemotherapy, radiation oncology, plastic surgery and clinical surgery. Of course, there are many clinical studies conducted that help in diagnosing and treating cancer. Click here dental consumables

Paediatrics is another branch of medicine that treats infants, children and adolescents. Pediatricians diagnose, treat and prevent diseases that are commonly associated with children. Some of these common diseases include diabetes, asthma, allergies, disorders of the immune system and obesity. Pediatricians can further diagnose, treat and prevent diseases that affect the development of children.

Of course, all medical professionals have their own specific areas of specialization. This is to help patients suffering from illnesses or diseases. Doctors can specialize in both internal medicine and external medicine. External medicine deals with diseases that can occur outside the human body such as travel, wounds, animals and germs.

Neurology is yet another branch of medical science dealing with the brain and nervous system. Neurons in the brain help carry out certain functions of our body. It helps our bodies to stay in shape and stay healthy by preventing diseases such as Alzheimer's disease and Parkinson's disease. Several subspecialties within neurology include pediatric neurology, geriatric neurology, cardiovascular neurology, rheumatology, ophthalmology and connective tissue neurology. These subspecialties are further divided into four main branches which are research, clinical, diagnostician and neonatology. Each of these branches has several sub-specialties.

The field of medicine is very vast. There are many different branches of medicine such as traditional Chinese medicine, Ayurveda, homeopathy, pediatric medicine, etc. Many people are turning to alternative forms of treatments for various diseases and one such treatment is Chinese medicine.

In China, people have been using traditional Chinese medicine for a very long time. This form of medicine is used not only to treat physical ailments but also to prevent and treat disease. It is used for promoting mental health as well. Chinese medicine has several critical care subspecialties like herbal medicine, qigong, diet therapy and traditional Chinese Medicine (TCM). People who opt for traditional Chinese medicine will also be exposed to other forms of complementary and alternative medicine.

There are subspecialties within clinical medicine. These include intensive care, trauma, geriatrics, neonatology, cardiology, gastroenterology, pediatrics, rheumatology and infectious diseases (usually flu and AIDS). Some of these physicians specialize in particular areas. For example, cardiothoracic and intensive care cardiothoracic physicians usually specialize in heart and cardiovascular disease. Geriatric and neonatal physicians typically specialize in diseases of the elderly and severe diseases of childhood.

A subspecialty within the field of radiation oncology deals with treating cancer and brain tumors. Other subspecialties in radiation oncology include thoracic oncology, vascular oncology, pediatric oncology and vascular pathology. Pathologists that work in this area are often involved in the diagnosis and treatment of patients with head trauma, cancer and other illness. Many physicians specialize in a specific field of therapy: pain medicine, cancer therapy, endocrinology, nutrition therapy or women's health, for example.

Neurological surgery is another specialty within medical specialties. Neurosurgery deals with disorders and diseases of the nervous system. It includes procedures like cerebrospinal fluid diagnosis, cranial CT imaging, cranial MRI, functional MRI, nerve compression and neuropsychological testing. An interventional radiologist performs surgery and radiography for neurological diseases. Other physician subspecialties in neurosurgery include neurologists who focus on diseases of the nervous, abdominal and pelvic systems; cardiologists who specialize in the treatment of cardiomyopathy, a disorder related to disease of the heart; and orthopedic surgeons who perform surgeries on disorders of the musculoskeletal system.

[lupine-publishers-sjo]

Lupine Publishers | Spontaneous Pneumothorax and Cavitated Lesions as First Manifestation of Metastatic Lung Adenocarcinoma to Ovary and Peritoneum in Young Patient?

Lupine Publishers | Journal of Otolaryngology Impact Factor

Abstract

We present the report of a case of lung cancer of atypical manifestation with important challenges in its diagnosis in a young                    woman who came in with pneumothorax tension, cavitated lung lesions, ovarian, hepatic and peritoneal masses and a biopsy                    compatible with pulmonary adenocarcinoma, whose initial approach raised the differential diagnosis of a tumor of gynecological                origin. A brief literature review was conducted.

Keywords: Pneumothorax; Pulmonary Cavitation; Pulmonary Adenocarcinoma; Ovarian Metastasis; TTF1

               Introduction

A 28-year-old woman who consulted the emergency                    department of the National Cancer Institute (Instituto Nacional                    de Cancerología) for a 7-month history of asthenia, adinamia,                    progressive dyspnea, low cough, loss of 17 kilograms of weight                    and the appearance of a painful mass at the level of the iliac fossa                    and right flank. Initially studied as an outpatient with presumptive                    diagnosis of granulomatous disease with negative serial baciloscopy                    and chest x-ray showing right atelectasis + right pneumothorax.                    In the tomography multiple solid nodules some with hypodense                    center involving both pulmonary fields, caverns of thickened walls                    in both apices, posterior segments of the lower lobes and upper                    segments of the lower lobes. In the abdominal tomography there                    is presence of mass surrounding uterus of 185*100*85 mm of                    density of soft tissues, which takes the contrast IV and cystic area                    of 85 mm in its right aspect of probable ovarian origin and hepatic                    compromise with apparent peritoneal sowings. Positive tumor                    markers AFP 1.2, ACE 392, CA 125 257. A right thoracostomy, fibro                    bronchoscopy with cultures for M. negative tuberculosis and biopsy                    of pelvic mass that reported lesion characterized by cords and                    neuroglandular formation of epithelioid cells of neoplastic aspect                    with a marked desmoplasic response were initially performed. For                    which the diagnosis of metastatic ovarian cancer to lung, liver and                peritoneum is made and send to initiate management.

               Case Report

Upon admission to the institution, pulmonary thromboembolism                    is ruled out and extensive pulmonary parenchymatous involvement                    (Figure 1(a)) is confirmed by nodular areas, most of them with                    central cavitation and frosted glass halo, which are accompanied                    by paramilitary consolidations, making it necessary to consider                    neoplastic metastatic involvement with cavitation, less likely                    infectious (angioinvasive aspergillosis). At abdominal level,                    extensive infiltrative involvement of the peritoneum, hepatic                    subcapsular with extension to the parenchyma in segment 6,                    gastrohepatic ligament, transverse mesocolon, descending                    mesocolon. Heterogeneous bilateral adnexal masses of neoplastic                    aspect (Figure 1(b&c)). Scarce ascites. We reviewed pathology                    material of ovarian mass biopsy with report of adenocarcinoma                    with reactive immunopurified for CK7, TTF1 and negative for GATA                    3, WT1, RE, CDX2, PAX 8 and CK20, we added NAPSIN which was positive, confirming lung metastatic origin (Figure 2(a&b)). The new                    fibro bronchoscopy with biopsy had immunohistochemistry that                    showed reactivity in tumor cells for TTF-1 and Napsin with absence                    of reactivity for p40, RE and RP. Compatible with compromise by                    non-small cell carcinoma, favors acinar pattern primary pulmonary                    adenocarcinoma. Less than 10% of all lung carcinomas debut with                    radiological cavitations, considered secondary to tumor necrosis by                    ischemia and/or bronchial obstruction [1]. Tokito et al. presented a                    cohort of lung cancer patients, with an incidence of cavitated lesions                    of 5.5% meanwhile in the Sing series this report is much higher                    near 9.6%. In both cohorts it was more frequent to find cavitations                    in men, over 60 years old, ex-smokers and with squamous cell                    histology [2].                

Figure 1: (a) Chest X ray; (b) Axial computed tomography with extensive pulmonary parenchymatous involvement.                    (c) Computed tomography of the abdomen and pelvis with mass surrounding uterus.

Figure 2: (b) Immunohistochemistry of Napsine A in lung tissue;                    (b) Immunohistochemistry of TTF1 in ovarian tissue.

Figure 3 Chest X ray.

a greater extent induced by oncologic management are infection                    and hemoptysis, very infrequently, the presence of spontaneous                    pneumothorax which is estimated between 0.03 and 0.05% of                    primary lung cancer with a poor prognosis [3,4]. Among 1200                    patients with spontaneous pneumothorax between 1970 and                    2007, 37 (3%) had lung cancer. In all patients, the pneumothorax                    occurred on the same side of the carcinoma. The main cause of                    spontaneous pneumothorax was rupture of a necrotic tumor                    nodule or necrosis of subpleural metastases (21 ptes)., As well as                    the communication between the bronchus and the pleural cavity,                    producing a bronchopleural fistula that results in pneumothorax                    [5]. Spontaneous pneumothorax in the context of lung cancer                    occurs in 75% of cases as an initial manifestation and the remaining                    25% during the course of the disease in patients with the known                    diagnosis, sometimes after the onset of management [6]. In this                    case, the first clinical manifestation of oncological disease was the                    presence of dyspnea secondary to spontaneous pneumothorax,                    infectious causes were ruled out and required surgical intervention                    with subsequent need for high oxygen flow. The main sites of                    lung cancer metastasis are pleura, brain, bone and liver. Ovarian                    metastases are rare, accounting for 5% of all ovarian cancers.                    The main tumors that metastasize to the ovary are from the                    gastrointestinal tract: colon and gastric, or originated in the breast.                    Lung cancer alone is the cause of these metastases by 0.3% [7].                    The metastases of an adenocarcinoma of the lung are difficult to                    distinguish from a primary carcinoma of the ovary. Although there is                    no specific lung marker, TTF-1 can be used to discriminate between                    primary pulmonary and ovarian. TTF-1 is positive in approximately                    63% of lung cancers [8]. Irving and Young reported 32 cases of                    metastatic to ovarian lung carcinoma in women aged 26 to 76. A                    history of lung carcinoma was documented in 53% of cases (17 out                    of 32), with detection of ovarian involvement at an interval of one                    year. In 10 cases (31%) ovary and lung occurred synchronously, in 5                    (16%) ovarian tumors were detected 26 months before lung injury.                    The most frequent histologic subtype was small cell carcinoma                    44%, adenocarcinoma in 34% and 16% in large cell carcinoma                    in 16% of patients. One third had bilateral presentation and the                    most frequent morphological characteristics were: multinodular                    growth, necrosis, lymphovascular invasion with rare involvement                    of the ovarian surface [9]. The management decision in this                    case was made considering the presence of pulmonary visceral                    crisis, the patient’s age, her ECOG and the high risk of rapidly                    deteriorating. Chemotherapy with palliative intention was started                    with carboplatin paclitaxel with a good clinical response in the two                    initial cycles, with which the requirement of supplementary oxygen                    and control of dyspnea was reduced. 40 days later, the patient was                    admitted with subite dyspnea of 3 days of evolution. with chest                    x-ray (Figure 3) that evidences left pneumothorax, ventilatory                failure and dies despite rescue procedure.

               Conclusion

Patients with cavitated tumors develop serious complications                    during or after chemotherapy or concomitance such as infection or                    massive hemoptysis. There are no reports of safety and efficacy of                    the use of chemotherapy in patients with advanced lung cancer with                    cavitated lesions. Some retrospective reports that have evaluated                    toxicity in this group of patients in the a 9% study developed                    hemoptysis, considering it as acceptable toxicity for this group of                    patients. Sandler et al reported that 30% of patients treated with                    carboplatin+paclitaxel+bevacizumab presented hemoptysis vs                    6% of those without cavitations. In our case, taxane and platinumbased chemotherapy were initiated while obtaining studies of                    EGFR, ALK, Ros 1 and PDL1 to optimize management, with the                    initial cycles the palliation objective was achieved. However, the                    subsequent occurrence of pneumothorax is a possible consequence                    of the effect of cytotoxic treatment on existing lung lesions. It is not                    clear from the literature what would be the safest scheme, dose or                    frequency for this population to avoid the development of this type                    of complications. It is necessary to increase the reporting of these                cases in order to try to elucidate their management.

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[paintmixing]

Mod search?

Hey, so obviously I haven’t been so active on this blog lately and I’m sorry. I’ll explain why under a read more because it involves issues with my dog that might be upsetting for some folks. However, for the foreseeable future I think it’s more realistic to be adding some mods to help post stuff.

If you’re interested in moderating this page (and you’re willing to keep up with the tag system, I use some tumblr extensions because spoons) please send me a message and I’ll discuss that with you. Thanks.

tw: animal illness, surgery, tumours (spoiler: she’s living & okay, don’t worry)

Okay, so I have a dog named China. She’s 12 and a jack russell and she’s an amazing grumpy lady. Her health started deteriorating pretty quickly before xmas & I had to take care of her more, she was tired out a lot and couldn’t go for walks anymore (we got her a stroller, it was the cutest and she was so happy to go back to the park) and right before xmas she got an ultrasound that showed she had 2 pretty decent sized tumors. Her vet since she was a puppy sat down and explained that she was basically dying, had maybe 6 months to live and very few options. It looked very inoperable. We were all pretty devastated. My dog however didn’t really understand she was unwell.

After the new year we sent her to do some more tests with a specialist vet including an MRI. It was a super risky surgery but one of their surgeons was willing to take the challenge and we knew the alternatives were palliative care so we weighed it up and decided to do it despite a lot of “if the tumors have gone here, we can’t take this out” and might need to palliate anyway.. oh and your dog has a 42-47% chance of dying during the surgery or a couple days after. But anyway on wednesday she had surgery. It removed all of her tumors, her adrenal gland and spleen and luckily she got to keep her kidney. They also did a biopsy on the liver lumps and found them to not be cancerous or even tumorous and she’s been put on antibiotics for that. It went surprisingly well and she was in ICU for 2 days. 

But fast forward to now and she is basically useless by herself and has to remain in a cage for 2 weeks while she recovers. She needs a lot of prompting and attention and I don’t think I have the energy for much else let alone this blog right now, maybe as she gets better. I’m really sorry about that. So that’s why I haven’t been posting really, and have had really bad focus and motivation issues and think I should get some new mods to keep the blog going.

[advinhealthcare]

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[stlouisdivorcelawyer]

Lung Cancer Tattoos For Grandpa

The vibrancy of a pink tattoo depends, in part, on your skin tone. A ribbon tattoo can also be appropriate for someone who is currently fighting that disease or who has beaten it in the past and is always fearful of a recurrence.

Pin On Awesome

Be sure to choose a tattoo artist with extensive experience in color.

Lung cancer tattoos for grandpa. The blue iris stands for hope & faith and of course the white ribbon. A cancer memorial tattoo makes a great gift for cancer patients and also a heartwarming memorial. Lung cancer that has spread to bone is very serious.

A peace sign is a symbol of peace but with this type of design you can. The tattoo is a tribute to her paternal grandfather ronald ray cyrus, who died on february 28, 2006. And my mom passed away from lung cancer.

Underneath the ribbons, it says, ‘courage, hope, strength.’ The cancerous tumors appear on the lungs’ lobes and appear to be the main cause for death of patients once they are diagnosed with this kind of illness. Lung #cancer #tattoo done on 6/7/14.

“this is a tattoo of a green ribbon (gastroparesis), white ribbon (invisible illness and lung cancer), and a blue ribbon (chronic illness). See more ideas about memorial tattoo, memorial tattoos, mom tattoos. No matter how you spread awareness, make sure it’s meaningful for.

Lung cancer is a dreadful disease that has taken millions of lives all across the globe. There is no dearth of design possibilities when it comes to ribbons for cancer type of tattoos. One of the biggest reasons for getting a lung tattoo would be to highlight the breath in some way.

Cancer ribbon tattoos are also worn as a memorial sign by people who have lost a friend or a loved one due to cancer. See more ideas about grandpa quotes, grandparents quotes, family quotes. Cancer can be a devastating diagnosis, but it doesn’t mean the end of the fight.

The cause of lung cancer is generally connected with tobacco smoking and exposure to harmful pollutants. Cross with a cancer ribbon. “this is a tattoo of a green ribbon (gastroparesis), white ribbon (invisible illness and lung cancer), and a blue ribbon (chronic illness).

Lavender color is supposed to represent cancer in general, with yellow for cancer of the bladder, gray is for the brain, pink is for breast cancer, cervical by white, childhood cancer by gold, dark blue for colon and so on. At this stage one utilizes therapy for palliation. “breast cancer can stick it!” the quote “breast cancer can stick it!” is done in chunky block lettering around the black line art of woman playing the drums, abstractly colored in shades of pink,.

Whatever the reason, a lung tattoo is a great choice to get tattooed onto your body. Pink cancer ribbon tattoos can be personalized or plain, stand on their own or blend into a design or larger piece of ink. Cancer ribbon tattoos are often portrayed in colorful bows and designs, where the shade of the color signifies the type of cancer the tattoo is referring to.

These are small cancer memorial tattoos that are easy to dedicate to someone special, yourself, or the cause itself. For example, a pink ribbon indicates breast cancer and lung cancer is denoted by a white ribbon. Whatever the situation, there is no reason not to get a tattoo of a cancer ribbon to remind yourself and others that you or someone you know has been afflicted with such a terrible disease.

My grandpa is 75 yrs old and suffering from lung cancer it has spread to bones.what stage is he in. Perhaps you want to reflect the breath of life. He calls this one “grandpa slams lung cancer.” he’s using the platform to raise awareness with the white ribbon project.

However, there are many unknown reasons too due to which this fatal disease can affect you. Listen,the purpose of this video is to show my love for him ️and i hope you enjoyed! Lung cancer awareness products with the white or pearl awareness ribbon designs to show your support.

Grey ink flying birds and lung cancer tattoo. Lung cancer tattoos designs, ideas and meaning. Showing post nuclear war damage small picture designs is an excellent way to express your support for the armed forces.

Lung cancer ribbon picture designs for men. Some of the most liked ribbons for body art are the lung cancer ribbon, small picture designs and peace signs. Our lung cancer awareness designs are available on shirts, mugs, buttons, keychains, stickers,.

I have gastroparesis as well as a few other chronic/invisible illnesses. Beautiful lung cancer awareness tattoo design. 4 doctor answers • 10 doctors weighed in.

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[dave-kevic]

Bone Metastasis: A Cancer Caused By Cancer

Medical Diagnosis has advanced monumentally in recent years. Regardless, prior detection of Bone Metastasis can be complicated, and the detection of its presence often means that the patient has reached an advanced disease stage and has only a little time left with a few likely treatment options.

The foremost goal of these treatment options is not to overcome the condition but rather to relieve the associated pain, prevent further bone complications, and sustain a good quality of life. Upon diagnosis of the first metastatic bone cancer, the life expectancy is often around 6-48 months.

What Is Bone Metastasis?

Bone Metastasis is most commonly observed in patients suffering from lung, prostate, and breast cancer. It occurs in advanced cancer patients when cancerous cells from the primary tumor move to the bone.

Its symptoms include weakness in legs or arms, broken bones, bone pain, bowel and urinary incontinence, and hypercalcemia (a condition where high levels of calcium are seen in the blood), which lead to nausea, constipation, vomiting, and confusion.

Since this condition has adverse clinical consequences, a prompt and precise diagnosis is thus necessary. The diagnosis usually includes looking for symptoms, signs, and imaging. Laboratory tests include Plain X-ray, Computed Tomography (CT), and Radionuclide Bone Scintigraphy that can be used as the imaging methods for detecting Bone Metastasis.

What Are The Treatment For Bone Metastasis?

According to the reports, breast cancer has the highest prevalent cases of Bone Metastasis, with around 121,603 reported cases in 2020, within the metastatic group in the United States, followed by lung cancer, prostate cancer, and other solid tumors.

Further analysis shows that the number of cases of Bone Metastasis established on tumor type could climb by 2030 due to the increasing incidence of cancer globally, which could make a positive shift in the Bone Metastasis market.

A study of the Bone Metastasis Treatment Market describes the current therapies, the key companies, and the emerging pipeline in further detail. The study also indicates the progression of developmental stages and the survival rate of Bone metastasis as observed in many patients over the years.

Bone Metastasis is hardly ever cured, and the only way of treatment is through disease control, performed using systemic anticancer therapies built on multidisciplinary supportive care.

This care includes using denosumab or bisphosphonates (a bone-targeting agent) to prevent skeletal morbidity and inhibit tumor-related osteolysis. Appropriate local treatments such as specialist palliative care, radiation therapy, orthopedic surgery are further used to reduce the impact of metastatic bone disease on bodily functioning.

The Future

It is necessary to develop novel strategies that improve the patient's quality of life by averting skeletal disease and palliating established skeletal events. In addition, more studies are vital for understanding the interaction between the tumor cell and bone microenvironment so that effective new therapeutic interventions can be developed.

The entry of important pharmaceutical companies pioneering novel effective therapies, the discovery of new biomarkers for diagnosis, and R&D, shall propel the Bone Metastasis market landscape and treatment frame. With growing awareness of Bone Metastasis among people, the complete Bone Metastasis treatment landscape could change significantly in the coming years.

[healthcare-market]

Interventional Pulmonology Market Estimated to Expand at a Robust CAGR by 2025

Global Interventional Pulmonology Market: Overview

Interventional pulmonology is a branch of medical science that deals with minimally invasive medical procedures carried out under image guidance by interventional pulmonologists for the diagnosis, treatment, and palliation of different types of pulmonary disorders. Interventional pulmonology procedures involve usage of different image guided techniques such as computed tomography, fluoroscopy, and ultrasound to diagnose and treat the specific site affected with pain or cancer. Interventional pulmonology procedure is most commonly performed with other cancer treatments such as surgery, chemotherapy, and radiation therapy. These procedures offer several advantages such as quicker recovery, shorter hospital stay, minimal side effects, and more precise and accurate treatment compared to other therapeutic procedures.

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Global Interventional Pulmonology Market: Trends and Opportunities

The global interventional pulmonology market is primarily driven by high prevalence and increase in incidence rates of lung cancer across the world. Lung cancer is one of the leading causes of death globally. According to the World Health Organization (WHO), lung cancer accounted for 2.9 million deaths in 2018. Moreover, increase in incidence rates of chronic obstructive pulmonary disorders, airway strictures, and amyloidosis across the world is projected to boost the growth of the global interventional pulmonology market during the forecast period. Furthermore, advantages of minimally invasive surgical procedures, technological advancements in interventional pulmonology, and increase in government funding for oncology procedures are anticipated to fuel the growth of the global market during the forecast period.

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Global Interventional Pulmonology Market: Segmentation

The global interventional pulmonology market can be segmented based on procedure, indication, and region. In terms of procedure, the market can be divided into tumor debulking, endobronchial brachytherapy, endobronchial stenting, photodynamic therapy, and others. Tumor debulking procedure refers to the removal of tumor growing within the airway lumen endoscopically either by heating, freezing, vaporizing, or simply by resecting the tumor by with biopsy. Different techniques such as endoscopic laser resection, electrocoagulaion, and cryotherapy have been used for the removal of the tumor. Endobronchial brachytherapy procedure involves administration of high dose radiotherapy through the catheter at the surgical site in the airway. Endobronchial stenting procedure involves the placement of stents to relieve the symptoms of airway obstruction. Different types of metallic as well as silicone stents are currently available in the market and demand for these stents is increasing. Based on indication, the global interventional pulmonology market can be classified into lung cancer, chronic obstructive pulmonary disorder (COPD), carcinoid tumors, airway strictures, amyloidosis, tuberculosis, and others. The lung cancer segment is projected to dominate the global market from 2018 to 2026 owing to significant burden of lung cancer across the globe.

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Global Interventional Pulmonology Market: Regional Analysis

Geographically, the global interventional pulmonology market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America and Europe are anticipated to account for major shares of the global market due to large population afflicted with chronic lung cancer, chronic obstructive pulmonary disorders, airway stricture, and airway related disorders. Moreover, significant adoption of minimally invasive surgeries for the effective management of airway disorders, well-established health care infrastructure, and early adoption of technologically advanced interventional pulmonology products are likely to fuel the growth of the market in these regions during the forecast period. The interventional pulmonology market in Asia Pacific is expected to expand at a high CAGR during the forecast period due to rise in prevalence of cancer in the highly populous countries of India and China, rapidly changing health care systems, various government initiatives to improve overall health care, and increased per capita health care expenditure. Moreover, rise in investments by leading global interventional pulmonology devices companies in the region is likely to contribute to the growth of the market in Asia Pacific during the forecast period.

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Global Interventional Pulmonology Market: Companies Mentioned

Key players operating in the global interventional pulmonology market include Boston Scientific Corporation, Medtronic plc, Terumo Corporation, BTG plc, AngioDynamics, Inc., Ethicon, Inc. (Johnson & Johnson), Merit Medical Systems, Inc., Eckert & Ziegler BEBIG, Varian Medical Systems, Inc., HealthTronics, Inc., Röchling Group, Pulmonx, Inc., EndoChoice, Inc., ENDO-FLEX GmbH, and Karl Storz.

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Juniper Publishers- Open Access Journal of Case Studies

Orbital Metastasis as Primary Presentation of Misdiagnosed Breast Cancer: A Case Report

Authored by Lazareva E

Abstract

We report the case of orbital metastasis from a hormone-positive infiltrating lobular carcinoma in a previously misdiagnosed metastatic breast cancer in a 61-year old woman presenting with ophthalmic symptoms (diplopia, bulb proptosis). She received external beam radiotherapy, particularly 3D conformal radiotherapy, chemotherapy and hormone therapy. The metastatic involvement of the orbit in malignant tumors is a rarely diagnosed condition. Breast cancer accounts for the majority of these cases. This article highlights the importance of evaluating the one such unique metastatic site (orbital metastasis) as the first indication of advanced malignancy and reinforces the importance of an early correct diagnosis.

Keywords: Blood pressure Baseline echocardiography Mitral valve prolapse Mitral regurgitation

Introduction

Breast cancer is a histologically heterogeneous disease. Infiltrating ductal carcinoma (IDC) accounts for approximately 90% of breast cancers, whereas infiltrating lobular carcinoma (ILC), the second most common breast carcinoma, comprises approximately 10% of breast cancers [1,2]. The histopathologic appearance of ILC is different from that of IDC. Whereas IDC often metastasizes to the lung, liver, bone, and brain, ILC tends to spread to the gastrointestinal tract, genitourinary tract, peritoneum, retroperitoneum, and leptomeninges [2-7]. Some investigators have suggested that, compared with IDC, ILC has a higher distant metastasis rate [3,4,8], likely because of its infiltrative nature. It has been postulated that in ILC loss of E-cadherin, the cell-to-cell adhesion molecule, facilitates the metastasis process. Like ILC in the breast, metastatic ILC tends to infiltrate the affected organs in a diffuse process instead of forming a discrete tumor nodule.

The high incidence of breast cancer ocular metastasis may be related to the longer life expectancy of metastatic breast cancer patients, thus providing a longer time for intraocular metastasis to develop. It is therefore important to recall this diagnosis. The majority of symptomatic patients note a decreased visual acuity at the time of presentation. Other presenting signs or symptomsinclude ptosis, eye lid swelling and diplopia. Often, the possibility of an inflammatory process is raised. An excision biopsy often confirms the seemingly improbable diagnosis of an orbital metastasis. Orbital metastases remain an unfavorable prognostic factor, but the diagnosis and treatment are still important in order to prevent loss of vision and improve the patient’s quality of life. As previous studies have shown, the overall survival rate is still as limited as nearly half a century ago. Ocular metastases have become less rare since the systemic treatment with chemotherapy prolongs survival in patients with cancer.

Breast cancer is primary cancer most frequently found in the case of orbital metastases (29-51%) [9]. Lobular breast cancer represents the cancer subtype with the highest prevalence among orbital metastases. The high frequency of ILC in orbital metastases illustrates the special metastatic behavior of this tumor entity and may have implications for the understanding of the organotropism of metastatic lobular breast cancer [10].

We report the case of a patient who was discovered with orbital metastasis (OM) from an unknown breast cancer. This is a rare case of an orbital metastatic carcinoma preceding the diagnosis of a nonpalpable primary breast carcinoma.

The importance of emergency treatment for rapidly progressing lesions is stressed as well as the need for detailed treatment planning to prevent possible damage to sensitive normal structures.

Case Report

A 61-year-old woman presented with a history of gradually worsening blurred vision, periorbital swelling, pain and proptosis in the right eye. Magnetic resonance imaging (MRI) of the brain and orbits showed a diffuse abnormal enhancement involving the right orbit (Figure 1). The differential diagnosis included severe inflammatory response, pseudotumor, lymphoma, primary or metastatic neoplasia. The patient was referred to Division of Hematology to confirm a suspicion on lymphoma. The biopsy was submitted to the Ophthalmology Division where the possibility of lymphoma was excluded. Histologically, the biopsy demonstrated metastatic carcinoma of possible primary breast cancer estrogen receptor (ER) positive, progesterone receptor (PR) positive. The diagnosis of carcinoma was made; however, the site of origin of carcinoma was not yet determined. Chest and abdominal CT scan and mammography were negative. Since lymphoproliferative lesions are the most common primary orbital tumor in older adults (≥60 years of age), representing a spectrum of disorders and radiologic examinations do not allow reliable differentiation between benign and malignant lymphoproliferative disorders, hematologists indicated right enucleation. The surgical procedure was eventually carried out. The pathology report of the enucleated eyeball identified a microscopic focus of accumulated carcinoma cells (small cell carcinoma) in the sclera. While, the pathology report of the biopsed orbital masses demonstrated hypercellular population of small cells that interdigitate betweencollagen bundles in a single line, so-called “Indian file“. On immunohistochemical stains, the tumor cells from the orbital mass tissue were positive for ER, S100, CKW, CK AE1/AE3 and Lyzozim. These cells were negative for Plasma cell, Vimentin, TTF, PR, Melanoma, Melan A, LCA, SYN, Chromogranin, E-cadherin, CK 20, RCC, NSE and Actin. The findings were suggestive of metastatic lobular breast cancer. Post-operative MRI of the orbits demonstrated an expansile extraconal-intraconal mass that involved retrobulbar fat, eyelid, extraocular muscles, right nasolacrimal duct and right optic nerve (Figure 2). Postoperative chest CT scan revealed inhomogeneous loose tissue in left armpit. Cytological FNAB (fine needle aspiration biopsy) finding was negative for atypical cells. Some forms of invasive lobular carcinoma (ILC) do not present with a palpable mass as ILC is less likely to be associated with a fibrous tissue reaction. No further diagnostic studies were taken to rule out primary breast cancer (MRI, digital tomosynthesis) or primary lung cancer (bronchoscopy).

We believe that variability in the diagnostic report provided by pathologist was probably due to the common morphological features of the lobular carcinoma and small cell carcinoma. Both tumor cell lines are small, morphologically. Tumor cell of lobular carcinoma tends to have a loss of expression of E-cadherin. Small cell cancer tumors usually express chromogranin A and synaptophysin in >50% of the cell population. Small cell breast carcinoma is a very rare (the literature describes <40 cases), yet highly aggressive variant of a neuroendocrine carcinoma. The first challenge in the proper diagnosis of small cell carcinoma of the breast is to determine whether it is breast primary, or whether it is in fact a ‘secondary’ site metastized from another cancer elsewhere in the body, (and the lung would be the first place to look). It is impossible to distinguish metastatic and primary smallcell breast carcinomas on the basis of histological evaluation. Treatment by paclitaxel, cisplatin and etoposide have shown to be highly effective against the spread and recurrence of small cell breast carcinoma. Finally, based on the pathologist’s examination and diagnostic radiology exams, first-line systemic chemotherapy of metastatic extrapulmonary small cell carcinoma was initiated using Cisplatin 75mg/m2 and Paclitaxel 175mg/m2 (x 6 cycles) and sequential external beam radiotherapy, particularly 3D conformal radiotherapy to the orbit to a cumulative dose of 3000cGy.

One year after the initial diagnose she found a lump in the left breast and in the left underarm area. Based on the mammogram report and FNA cytology, she underwent through left modified radical mastectomy (Histologic type: ILC, pTNM pT2 size of carcinoma 3.5cm pN3 19/19 extranodal extension G3 L1 Stage IIIC, hormone receptor status ER 3+ 95%, PR – 5% Her2/neu 2+, SISH negative, Ki 67 1+ 15%, p53 - 5%) and was started on hormone therapy with aromatase inhibitor. The post-radiation MRI of the orbits demonstrated almost complete radiologic response (Figure 3). On a follow-up visit 36 months after her breast surgery, she was disease free. Three months later, computed tomography of the abdomen revealed features of both small and large bowel obstruction with moderate ascites, left hydronephrosis with ureteral obstruction and gastric wall thickening. Arrangements for palliation were made. A ileostomy was performed. She passed away 4 years after her initial orbital manifestation.

Discussion

Orbital metastasis is relatively uncommon. In general patients with metastatic disease do not develop orbital metastases, being identified clinically in less than 1% of cases. Orbital symptoms occur well before local symptoms from the primary tumour manifest, and as such are the first indication of advanced malignancy [11,12]. In contrast to IDC metastasis to the CNS, which tends to form metastatic masses in the brain parenchyma, ILC that metastasizes to the CNS has a strikingly high propensityto spread diffusely along the leptomeninges. Diffuse infiltrative enhancing soft tissue replacing the postseptal fat or connective tissue often accompanies the abnormally enhancing extraocular muscles. This diffuse infiltrative expansile process often causes proptosis. The Tenon capsule, sclera, and eyelid soft tissue may also be involved [13-16].

Common tumours that have a predilection to metastasise to the orbit include breast cancer, bronchogenic cancer, prostate cancer, gastrointestinal adenocarcinoma, thyroid carcinoma, renal cell carcinoma, neuroblastoma, Ewing sarcoma and Wilms tumour [9- 12,17,18]. Of all metastatic tumors to the orbit, breast carcinoma is considered to be the most prevalent primary tumor, accounting for 29% to 70% of all metastases [17]. It is possible that the actual frequency of breast cancer orbital metastases is much higher than that indicated in the published series. Metastatic involvement of ocular structures in breast cancer seems to be a rare clinical entity; nevertheless, autopsy histopathological inquiries propose that 10-37% of patients with breast cancer have detectable ocular or orbital metastasis [19]. Still many breast cancer orbital metastases remain subclinical and are never diagnosed [20].

Infiltrating lobular breast cancer is a special breast cancer subtype. It accounts for 10-15% of all mammary carcinomas and for ~1% of all malignancies [21]. ILCs display a distinct histomorphology and are almost always estrogen receptor (ER) positive [22]. The absence of the PR in luminal subtypes of breast cancer has a higher risk of relapse and lower disease-free survival [23,24]. This is in part due to an increase in hormone resistance among PR negative breast cancers [25]. PR negative lobular carcinoma confers a particularly poor response to hormonal therapy, and thus, a worse prognosis. ILC growth is strongly dependent on estrogenic stimulation [26]. The list of anatomical sites associated with ILC metastasis (ovaries, abdominal cavity, skin, bone) reads like a catalog of tissue compartments with a favorable steroid hormone supply. Estrogen concentrations are up to 1000-fold higher in ovarian tissue and peritoneal cavity fluid as compared with the body circulation [27]. Moreover, estrogens are produced by mesenchymal cells of the dermis, adipose tissue and bone [28]. Accordingly, ILCs seem to metastasize to sites of estrogen production. The most convincing case supporting this notion has been documented by Arnould et al. [29] they have reported an ILC metastasis within an estrogen-producing granulosa cell tumor of the ovary, which had developed under tamoxifen therapy [29]. There is indirect evidence that the orbital fat pad produces steroid hormones to regulate tear film composition [30,31]. Alternatively, orbital metastasis from ILBC may simply extend to the orbit from nearby bone metastases or from occult meningeosis carcinomatosa. The mean interval from diagnosis of primary breast carcinoma to detection of orbital metastasis ranges from 4.5 to 6.5 years [32]. After the diagnosis, the prognosis is poor: in fact, the median survival is 31 months, the median is 19 months with a range of one to 116 months [33]. Ocular metastasis can represent the initial manifestation of breast carcinoma, with up to 26% of orbital breast metastasespresenting before the discovery of the primary tumor [34]. The diagnosis of ocular metastases is based primarily on clinical findings supplemented by imaging studies (CT, MRI).

Orbital metastases originating from breast carcinoma predicts widespread metastatic disease in other organs. Systemic treatment of metastatic breast cancer may include some form of hormone therapy and/or chemotherapy depending on the overall disease burden [35]. Enucleation offers no advantage concerning disease progression or survival [32]. Orbital surgery is primarily used for diagnostic rather than therapeutic purposes given that the disease is usually widespread at time of diagnosis and is not curative. In selected cases, tumor resection, even if incomplete, may be appropriate to improve symptoms of pain, diplopia, and proptosis. Treatment is primarily with radiotherapy, typically with a total dose of 20 - 40Gy [11]. It is usually administered to control tumor growth, preserve visual function in the short term, decrease proptosis and exposure keratopathy, or to improve patient comfort [32].

Conclusion

In summary, although rare, orbital metastasis can be the initial and sole presenting feature of breast cancer. It can occur in the presence of normal breast examination or negative mammogram. It can be misdiagnosed as orbital pseudotumour. Patients with ocular symptoms such as ptosis, proptosis, diplopia, pain, exophthalmus, biopsy and histopathological examination of the orbital lesion should be considered, particularly in elderly. This case demonstrates the importance of the possibility of dual pathology, which may lead to diagnostic confusion. The pattern of ILC metastasis emphasizes its presentation at unusual sites such as the leptomeninges and orbit. This knowledge may aid in accurate imaging interpretation and treatment planning in patients with metastatic ILC of the breast.

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Global Medical Radiation shielding Market Size, Growth Analysis Report, Forecast to 2021-2027

The global medical radiation shielding market is anticipated to grow at a considerable CAGR of 6.5% during the forecast period (2021-2027). The market growth is primarily attributed to the rising incidence of cancer and the rising demand for nuclear radiation therapies for accurate diagnosis. Medical radiation shielding is used for radiologic applications including CT, MRI, PET & SPECT, X-ray, and other diagnostic imaging applications. The radiation shielding equipment is mainly used as a safeguard to protect the medical worker and patients from direct radiation during diagnostic imaging. The material used in the medical radiation shielding is environment friendly that allows human contact without any physical harm.

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Moreover, the increasing usage of nuclear medicine, an increasing number of installation bases of radiology equipment, and an increasing number of diagnostic imaging centers are also substantially contributing to the growth of the medical radiation shielding market. Radiotherapy has an important contribution to cure cancer and prevent it from returning, which uses high doses of radiation to kill cancer cells and shrink tumors.

A Full Report of Global Medical Radiation shielding Market is Available at: https://www.omrglobal.com/industry-reports/medical-radiation-shielding-market

At low doses, radiation is used in x-rays to observe a patient’s internal organs such as bones and teeth. Radiotherapy is presently an essential therapy in the management of cancer patients. It can also be used in the combination with chemotherapy for palliation. As per the National Cancer Institute, annually about 40% of cancer patients are cured by radiotherapy combined with other modalities, and 49% are cured by surgery, and 11% by chemotherapy across the globe.

Key questions addressed by the report

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Which segment and region dominate the market in the base year?

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How COVID-19 impacted the market?

o          Deviation from the pre-COVID-19 forecast

o          Most affected region and segment

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How players are addressing challenges to sustain growth?

Where is the investment opportunity?

Global Medical Radiation Shielding  Market Report Segment

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Radiation Therapy Shielding

Diagnostic Shielding

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United States

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Asia-Pacific

China

Japan

India

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Rest of the World

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