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Immunotherapy A Game Changer in Blood Cancer Treatment
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Blood cancers, containing leukemia, lymphoma, and myeloma, are a diverse group of diseases that affect the blood, bone marrow, and lymphatic system. Traditionally, therapies such as chemotherapy and radiation have been the mainstays for combating these cancers. However, in recent years, the emergence of immunotherapy has revolutionized the landscape of blood cancer treatment. This groundbreaking procedure harnesses the body’s immune system to fight cancer cells, offering new hope and improved outcomes for patients.
Understanding Immunotherapy:
Immunotherapy, also known as biologic therapy, is a type of cancer treatment that improves the body’s natural protection to combat cancer. Unlike traditional therapies that directly target cancer cells, immunotherapy stimulates the immune system to recognize and destroy cancer cells more effectively.
Types of Immunotherapy:
Dr. Pratik Patil offers several types of Immunotherapy for Blood Cancer Treatment in Pune Includes:
Checkpoint Inhibitors: These drugs target checkpoint proteins such as PD-1 and CTLA-4, which act as brakes on the immune system, preventing it from attacking cancer cells. By blocking these checkpoints, immunotherapy allows the immune system to recognize and attack cancer cells more effectively.
CAR T-Cell Therapy: Chimeric Antigen Receptor (CAR) T-cell therapy involves genetically modifying a patient’s T-cells to better recognize and attack cancer cells. This personalized approach has shown remarkable success in treating certain types of blood cancers, including acute lymphoblastic leukemia (ALL) and certain types of lymphoma.
Monoclonal Antibodies: Monoclonal antibodies are laboratory-produced molecules designed to mimic the immune system’s ability to fight off harmful pathogens. They can be used to target specific proteins in cancer cells or stimulate the immune system to attack cancer cells more effectively.
Immune Checkpoint Inhibitors: These drugs target proteins that help cancer cells evade detection by the immune system. Blocking these proteins allows the immune system to recognize and destroy cancer cells more effectively.
Benefits of Immunotherapy in Blood Cancer Treatment:
Targeted Treatment: Unlike chemotherapy, which can damage healthy cells along with cancerous ones, immunotherapy specifically targets cancer cells, minimizing damage to healthy tissues.
Long-lasting Effects: Immunotherapy can create a memory in the immune system, potentially providing long-term protection against cancer recurrence.
Fewer Side Effects: While conventional treatments like chemotherapy often cause notable side effects, such as hair loss and nausea, immunotherapy tends to have fewer and milder side effects.
Personalized Medicine: CAR T-cell therapy, in particular, is a highly personalized treatment that concerns changing a patient’s immune cells to target their specific cancer cells.
Looking for immunotherapy in Pune?
Dr. Pratik Patil is the best oncologist in Pune with experience of more than 10 years.He has special interests in immunotherapy treatment. For more information about cancer and  treatment options, or to book an appointment with the Cancer Specialist in Pune call +91 9637439163 or Click on Book Appointment for online booking.
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oncology-xpert · 2 years
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A genetic change that increases the risk of cancer can be passed down (inherited) if it is present in a parent's egg or sperm cells. For example, if a parent passes a mutated BRCA1 or BRCA2 gene to their child, the child will have a much higher risk of developing breast and several other cancers.
Healthcare providers typically do genetic tests (DNA tests) to confirm someone has an inherited (hereditary) cancer. If genetic tests show you have a hereditary mutation that increases your cancer risk, your healthcare provider may recommend that your family members have the same tests.
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breastsurgeonpune · 6 months
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Breast Cancer Specialist in Pune | Dr. Shily Dolas
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Are you looking for advice from a trustworthy breast cancer specialist in Pune? If you need thorough care and knowledge about managing breast cancer, go to Dr. Shilpy Dolas. Dr. Dolas gives people with breast cancer hope and recovery through his compassionate approach and emphasis on their well-being.
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ancureclinic · 1 year
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Other than Carpel Tunnel, there can be other reasons too which are responsible for Numbness and Tingling in wrist. . 🚩Save this Post for Later  . Suffering From Severe Chronic Pain?? DRAIN YOUR #PAIN TODAY: 
Book an Appointment Now:   074900 97611
Lower Abdominal Pain Treatment in Pune | Cancer pain treatment in Pune | Best Trigeminal Neuralgia Treatment Doctor in Pune
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dr-paritosha-dalal · 1 year
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https://drparitoshathakardalal.com/
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hepatobiliary · 2 years
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Hepatobiliary Cancer Treatment In Pcmc, pune 
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Overview of Hepatobiliary Cancer
Hepatobiliary cancer refers to tumors that develop in the liver, either hepatocellular carcinoma (HCC) or the intra- and extra-hepatic bile duct system, resulting in bile duct carcinoma (BTC). The hepatobiliary system includes the liver, gallbladder and bile duct. Hepatobiliary Cancer Treatment in Pune All these organs work together to make bile. The bile helps you to digest food in the small intestine. The liver makes the bile., while bile duct is a tube that passes bile from the r to the gallbladder and small intestine and the bile is stored in the gallbladder. Hence Hepatobiliary Cancer Treatment in PCMC generally refers to Liver cancer, Gallbladder cancer and Bile duct cancer
Kshirsagar Cancer Clinic is one of the best cancer clinic in Pimpri Chinchwad, PCMC, Pune. We have specialist Liver Cancer Doctors who can provide hepatobiliary cancer treatment for various stages of cancer.
The Hepatobiliary cancer surgeon or oncologist at our clinic are here to support you on your Hepatobiliary cancer treatment journey. Contact our clinic today to create a personalized treatment plan for you. Earlier you start the liver cancer treatment greater the likelihood of successful treatment & full recovery.
Symptoms of Hepatobiliary Cancer Treatment in Pune
Hepatobiliary cancer symptoms may vary depending on the Hepatobiliary cancer surgery in pcmc  type and the tissue affected.
Most people have no signs and symptoms in the early stages of primary liver cancer. When signs and symptoms appear, they may include the following:
• Weight loss without trying • Loss of appetite • Pain in the upper abdomen • Nausea and vomit • Weakness & fatigue • Swelling of Abdomin • Jaundice – Yellowing of the skin and whites of the eyes
For More Details:-https://drpankajkshirsagar.com/hepatobiliary-cancer-treatment/
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drsumitshah · 2 years
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What causes liver cancer?
At present, suffering from liver cancer is a much-talked topic. As per the research 2022 American Cancer Society, 41260 new patients are suffering from this cancer. Like other cancer, cancer cells develop in the liver and cause cancer.
Types of liver cancer
Varied cells in the liver can develop different types of cancerous and non-cancerous tumors. While cancer develops in the liver, it is known as primary cancer in the liver. This primary cancer can also be of different types like- HCC or Hepatocellular Carcinoma, Bile Duct cancer, Angiosarcoma, and hemangiosarcoma.
Secondary cancer that arises in the liver is popular as Metastatic cancer. Sometimes, these cancer cells spread to other body parts like the pancreas, lungs, colon, etc, and it becomes metastatic cancer. People need to consult a liver cancer specialist in Pune at the primary to get the best treatment.
What are the probable causes?
The prime reason for developing cancer is the alteration in the cells in the DNA. DNA instructs the cells for chemical progression in the human body. When a mutation occurs in the DNA, the cells become out of control and start growing rapidly.
Besides those above, consumption of heavy alcohol, excessive smoking, obesity, and hepatitis can cause this cancer.
Signs and symptoms
Many times, individuals don’t understand that they have cancer. But the experts of a liver cancer center in Pune mention that all need to check the signs below to understand whether anyone is suffering from cancerous cells.
Sudden loss of weight, loss of appetite
Pain in the upper abdomen and swelling
Suffering from nausea and vomiting
Discoloration of skin
Suffering from weakness and fatigue without much hard work
Depending on the symptoms and diagnosis, doctors will recommend whether the patient requires liver cancer Surgery in Pune. Patients can consult with Dr.Sumit Shah of the Prolife cancer centre in Pune for the best treatment.
About Dr. Sumit shah
Dr. Sumit Shah has treated thousands of patients suffering from Cancer. He is one of the few oncologists in Pune who perform Minimal Access (keyhole) Surgery to offer his patients a smooth & pain-free recovery from Cancer. He is a highly experienced Oncologist in Pune with 14 years of expertise in surgical oncology. He is the Founder of Prolife Cancer Centre and is the Chief Consultant, Surgical Oncologist & Laparoscopic Cancer Surgeon in Pune.
Having pursued a super specialty course at the Cancer Centre Welfare Home and Res. Institute, Kolkata, and being awarded as the Best Outgoing Cancer Surgeon from his Institute, Dr. Shah is one of the Best Surgical Oncologist in Pune, India who possesses this recognized degree in Surgical Oncology
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oncologysurgeon123 · 2 years
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Throat Cancer Doctor in Pimpri Chinchwad |Cancer Specilist In Pune | Dr. Ashish Pokharkar
Dr. Ashish Pokharkar is leading Cancer Specialist Doctor in Pune, Pimpri Chinchwad PCMC who offers you best facilities for diagnosis & treatment options for all types of Cancers & delivers best results to overcome Cancer.
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Targeted Therapy and Immunotherapy for Gallbladder Cancer
As researchers learn more about the changes in cells that cause gallbladder cancer, they’ve developed drugs to target some of these changes. These targeted drugs work differently from standard chemotherapy (chemo) drugs. They sometimes work when standard chemo drugs don’t, and they often have different side effects.
FGFR2 inhibitors:
FGFRs (fibroblast growth factor receptors) are proteins on cells that help them grow and divide normally. A small number of people with gallbladder cancer have changes in the genes that make FGFRs, which result in abnormal FGFR proteins that cause cells to grow out of control and turn into cancer.
Pemigatinib (Pemazyre) and futibatinib (Lytgobi) are FGFR2 inhibitors. They block the abnormal FGFR2 protein in gallbladder cancer cells and keep them from growing and spreading to other places.
These drugs can be used to treat some advanced gallbladder cancers that cannot be removed by surgery or have spread to distant areas after at least one previous chemotherapy treatment. For these drugs to work, your cancer must have an abnormal FGFR2 gene, so your cancer will be tested before starting any of these drugs.
These medicines are taken by mouth as tablets, typically once a day.
IDH1 inhibitor:
In some people with gallbladder cancer, the cancer cells have a change (mutation) in the IDH1 gene, which normally helps cells make the IDH1 protein. Mutations in this gene can lead to an abnormal IDH1 protein, which can stop cells from maturing the way they normally would.
Ivosidenib (Tibsovo) is an IDH1 inhibitor. It blocks the abnormal IDH1 protein, which seems to help the cancer cells mature into more normal cells. This drug can be used in people with advanced, previously treated gallbladder cancer, if the cancer cells are found to have an IDH1 mutation. Your doctor can test your cancer cells to see if they have an IDH1 mutation.
This drug is taken by mouth, once a day.
Less common but more serious side effects can include changes in heart rhythm, pneumonia, and jaundice (yellowing of the eyes and skin).
NTRK inhibitor:
A very small number of gallbladder cancers have changes in one of the NTRK genes, called NTRK gene fusions. Cells with these gene changes make abnormal TRK proteins, which can lead to abnormal cell growth and cancer.
Larotrectinib (Vitrakyi) or entrectinib (Rozlytrek) are NTRK inhibitors. TRK inhibitors target and disable the proteins made by the NTRK genes. This drug can be used in people with advanced gallbladder cancer, who have not received prior systemic therapy.
These drugs are taken as pills, once or twice daily.
Possible side effects of NTRK inhibitors:
Common side effects can include abnormal liver tests; decreased white blood cell and red blood cells; muscle and joint pain; tiredness; diarrhea or constipation; nausea and vomiting; and stomach pain.
Less common but more serious side effects can include mental changes, such as confusion, changes in mood, changes in sleep; liver damage; changes in heart rhythm and/or function; vision changes; harm to a fetus.
BRAF inhibitor:
In some gallbladder cancers, the cells have changes in the BRAF gene. Cells with these changes make an altered BRAF protein that helps them grow. Some drugs target this and related proteins. A combination of BRAF inhibitor and a MEK inhibitor is often given together to treat advanced cancer with the BRAF V600E mutation.
Dabrafenib (Tafinlar) is a BRAF inhibitor. Trametinib (Mekinist) is a MEK inhibitor. This drug combination can be used in people with advanced, previously treated gallbladder cancer, if the cancer cells are found to have an BRAF V600E mutation.
These drugs are taken as pills or capsules each day.
Possible side effects of BRAF inhibitor:
Common side effects can include skin thickening, rash, itching, sensitivity to the sun, headache, fever, joint pain, tiredness, hair loss, nausea, and diarrhea.
Less common but more serious side effects can include bleeding, heart rhythm problems, liver or kidney problems, lung problems, severe allergic reactions, severe skin or eye problems, increased blood sugar levels, and squamous cell skin cancer.
RET inhibitor:
In a small percentage of gallbladder cancers, the tumor cells have a rearrangement in the RET gene that causes them to make an abnormal form of the RET protein. This abnormal protein helps the tumor cells grow. 
Selpercatinib (Retevmo) or pralsetinib (Gayreto) are RET inhibitors and can be used to treat advanced gallbladder cancers with the RET rearrangement.
These drugs are taken by mouth as capsules, typically once or twice a day.
Possible side effects of RET inhibitors:
Common side effects can include dry mouth, diarrhea or constipation, high blood pressure, tiredness, swelling in hands and/or feet, skin rash, muscle and joint pain, low blood cell counts, or changes in other blood tests.
Less common but more serious side effects can include liver damage, lung damage, allergic reactions, changes in heart rhythm, bleeding easily, and problems with wound healing.
KRAS inhibitor:
In some gallbladder cancers, the cancer cells have changes in the KRAS gene called a KRAS G12C mutation.  This mutation makes an abnormal form of the KRAS protein, which helps the cancer cells grow and spread.  KRAS inhibitors attach to the KRAS G12C protein, which helps keep cancer cells from growing.
Adagrasib (Krazati) is a KRAS inhibitor and is used to treat advanced gallbladder cancer with the KRAS G12C mutation if you’ve already had at least one other type of drug treatment.
This drug is taken as a pill, typically twice a day.
Possible side effects of KRAS inhibitor:
Common side effects can include diarrhea, nausea and vomiting, muscle pain, fatigue, cough, decreased white blood cell and red blood cell counts, and changes in other blood tests.
If you need targeted therapy and immunotherapy for gallbladder cancer, please book an appointment with our cancer specialist in Pune, Dr. Pratik Patil.
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retevmocapsule · 10 days
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Retsevmo and Retevmo Available in India
Retsevmo/Retevmo (selpercatinib) is a prescription medication used to treat certain cancers, including lung and thyroid. It targets RET gene mutations, offering a powerful treatment option for patients with these specific cancer types. If you want to buy Retsevmo online in India, please contact Indian Pharma Network (IPN). Specializing in sourcing hard-to-access medications such as Retsevmo, IPN is dedicated to ensuring that patients worldwide, including in India, receive critical, life-saving treatments promptly and efficiently. With IPN’s reliable global network, you can easily order oral Retsevmo from India and have it delivered directly to your location. For more information on how to buy Retsevmo capsules online.
Retsevmo (Selpercatinib) is a targeted therapy used to treat certain types of cancers, such as non-small cell lung cancer (NSCLC) and thyroid cancer. For patients/doctors/hospitals looking to buy Retsevmo in India, it can be challenging due to limited availability in the country. Indian Pharma Network (IPN) specializes in sourcing hard-to-access medicines like Retsevmo. We help facilitate the supply of this life-saving drug across India and globally, ensuring patients receive it promptly. With our international offices in Bulgaria, Belgium, and Hong Kong, we can move medicinal products promptly to every corner of the world. If you need assistance to buy Retsevmo in India.
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Retsevmo (Selpercatinib) is a prescription medicine widely used to treat certain types of cancers, such as non-small cell lung cancer (NSCLC) and thyroid cancer, in patients with specific RET gene mutations or fusions. Legal access to Retsevmo in India can be challenging due to limited availability. Indian Pharma Network (IPN) specializes in helping patients, doctors, and hospitals source hard-to-access medicines like Retsevmo. IPN ensures the global delivery of this medicine to every corner of the world, including India. Whether you're a patient or healthcare provider, IPN facilitates the supply of Retsevmo under Named Patient Programs (NPP), ensuring timely access to critical medications. For more information or to place an order.
Retsevmo (Selpercatinib 40 mg) is an FDA-approved oral medication used to treat specific types of lung, thyroid, and other cancers that are caused by abnormal RET genes. It targets and blocks cancer cell growth, providing a personalized approach to cancer treatment. If you’re looking to buy Retsevmo 40 mg capsules, Indian Pharma Network (IPN) can assist in facilitating the supply. Whether you're a patient, doctor, or hospital, we help source hard-to-access medicines like Retsevmo globally. IPN ensures quick and reliable delivery to every corner of the world, offering peace of mind during critical moments.
Retsevmo (selpercatinib 80 mg) is a therapeutic drug used for the treatment of lung and thyroid cancers with a genetic mutation in the RET gene. It is the first therapeutic option available for individuals with an abnormal RET gene. Buy Retsevmo 80 mg capsules at the lowest from India. Indian Pharma Network (IPN) is offering Retevmo Selpercatinib 80 Mg Capsules in New Delhi, Noida, Lucknow, Pune, Bengaluru, Chennai and other major cities in India. Check the best price of Retsevmo (Selpercatinib 80 mg). This oral medication is often hard to access, but with IPN’s network, patients, doctors, and hospitals can order it from trusted international sources.
Retsevmo or Retevmo (Selpercatinib) is a prescription medication used to treat certain types of cancers, including non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC), and other tumors caused by RET gene alterations. If you are looking for Retsevmo in New Delhi, the Indian Pharma Network (IPN) is here to help. We specialize in sourcing hard-to-access medications like Retsevmo and ensuring they reach patients, doctors, and hospitals in every corner of the world.
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Childhood cancer
Every year, over four Lakh cases of childhood cancer are detected in the world and 50,000 cases are detected in India. 2018, Global Initiative of Childhood Cancer was announced by World Health Organisation. Golden Ribbon is universal symbol for childhood cancer awareness and September is the golden month for awareness of childhood cancer.
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Urethral Stricture Treatment in Pune
Are you suffering from urethral stricture? Urolife Clinic in Pune offers advanced and effective treatments to alleviate this condition. Our experienced urologists, led by Dr. Irfan Shaikh, specialize in diagnosing and treating urethral strictures using the latest techniques.
What is Urethral Stricture?
Urethral stricture is a condition where the urethra, the tube that carries urine from the bladder out of the body, becomes narrowed or blocked. This can cause difficulty urinating, urinary frequency, painful urination, and even urinary retention.
Causes of Urethral Stricture
Urethral strictures can be caused by various factors, including:
Injury or trauma: Accidents, surgeries, or infections can damage the urethra.
Infections: Sexually transmitted infections (STIs) or urinary tract infections (UTIs) can lead to inflammation and scarring.
Radiation therapy: Radiation treatment for prostate cancer or other pelvic cancers can damage the urethra.
Congenital defects: Some people are born with a narrow urethra.
Treatment Options for Urethral Stricture
If looking for Urethral Stricture treatment in Pune, Consult Dr. Irfan Shaikh at Urolife Clinic — Urethral Stricture Treatment Doctor in Pune.The treatment for urethral stricture depends on the severity of the condition and the underlying cause. Our urologists at Urolife Clinic offer a variety of effective treatment options, including:
Dr. Irfan Shaikh and his team at Urolife Clinic are committed to providing compassionate and effective care for patients with urethral stricture. If you are experiencing symptoms of this condition, please contact us to schedule a consultation.
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ancureclinic · 1 year
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Yoga+ Medication = A Great Fit for Arthritis - Is It?
There is no doubt about the fact that Arthritis is one of the most painful diseases and it can cause a lot of problems if you do not take care of it at the right time. Arthritis treatment tends to have different details for each person and hence what might work well for you, does not work in the same way for others.
The one thing that you need to keep in mind is that having arthritis does not mean it's the end of the world. There are usually a lot of ways in which you can treat Arthritis and you will see that even professional doctors will suggest you try more things other than traditional medicines. One of the most common treatments for arthritis pain is none other than Yoga. But does it really work that well? It would be wrong to say that only one component can do its miracle.
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dr-paritosha-dalal · 1 year
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Most Common type of Cancer in Children
Cancer is one of the most rapidly rising non-communicable diseases, and it has not spared children. However, the cancers that affect youngsters differ from those that affect adults. Unlike lifestyle or environmental variables, early DNA changes are known to cause childhood cancers.
Every year, more children are diagnosed with cancer. Nearly 50,000–60,000 children in India are thought to have the condition, and there are undoubtedly many more who go undiagnosed or are unable to receive timely treatment. Due to a variety of reasons, the numbers are only anticipated to increase in the upcoming years. Cancer is still an illness that can be effectively controlled or treated if detected early, just like for adults.
Are cancers in children curable?
Even though they are frightening, childhood malignancies are very treatable if detected early and correctly. Nearly 80% of pediatric malignancies are treatable. If cases are caught early, children can enjoy longer, simpler lives without cancer. Lack of knowledge about signs and symptoms is one of the most frequent causes of why many youngsters do not receive a proper diagnosis. The signs and symptoms of juvenile cancer can differ from those of adult tumors in certain ways.
The most common type of cancer in children:-
Leukemia, or blood cancer
 Leukemia, which is defined as a condition of the bone marrow when the body produces unwanted white cells or lymphoblasts instead of blood, affects roughly 30% of children with cancer.
Both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), which can both be effectively treated provided the diagnosis is obtained in time, are forms of leukemia.
Infections and changes in the look of the skin, which are brought on by the abnormal production of white blood cells, can be leukemia’s signs and symptoms. If you as a parent see any of the warning signs highlighted below consult a Pediatric Cancer Doctor:
-Pale (White/Yellow skin)
-Frail immunity
-Recurring fever
-Anaemia
-Lethargy, dullness
-Profuse bleeding, low platelet count.
-Bone pain, aches, joint swelling
Other, less typical leukemia symptoms include headaches, nausea, vomiting, and squinting of the eyes. Blood cancer can be identified with the aid of a bone marrow test, which can identify the existence of malignant cancer.
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drsumitshah · 2 years
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Dr. Sumit shah   is a well-known best Liver Cancer Doctor in Pune He is an expert in Liver Cancer Treatment in Pune and one of best  Liver Cancer Hospital in Pune For any type of Patient suffering from liver Cancer problem Visit Dr. sumit Shah at Pro Life cancer center
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