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Favipiravir  CAS: 259793-96-9

Product: Favipiravir

CAS No.: 259793-96-9

Synonyms: T705; 6-fluoro-3-hydroxypyrazine-2-carboxamide; 6-fluoro-3-hydroxy-2-carboxamide

Availability: In Stock

MF.: C5H4FN3O2

MW.: 157.1025632

Appearance: Yellowish to off - white crystalline powder

Purity: 98%

Application: For research use only

Storage: RT

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[buyfavimol-blog]

Buy Favimol

As it is known, the world has been trying to fight the Corona virus for close to a year. In addition to the lack of a known treatment until now, it has focused on vaccine development studies in countries. Considering that the new social life has changed completely, people are almost unable to leave their homes, let alone talk to each other. Some countries, on the other hand, started to try and use some drugs, although there was no definitive result in the treatment in this process. For example, the drug called Favimol is used in the treatment of seasonal flu in China and Japan. After the disappearance of the effect of the virus in these countries has come to the fore, the number of those who buy favimol has also increased rapidly.

Having purchased buy favipiravir is not a definitive solution for Corona treatment, but we know that the drug was used experimentally. The Japanese company that developed Favipiraviri is also supported by Chinese experts. One of the reasons is that the drug is not on the agenda in Turkey also have a moderate effect on Covidien-19 treatment. It recommended drugs by the Ministry of Health in Turkey, which is highly effective at finding standing Covidien-19 can be monitored. It is also underlined that the drug is currently in the most effective group against the virus, although it has not yet been proven how it works in hospitalized patients who buy favira. The world is in a big spiral now and people are bored with the situation they live in. So a lot of people in Turkey until it found out that if the ban starts again aimed at keeping as far away from this virus.

Reference : https://buyfavimol.blogspot.com/

[marketresearchindia]

Growth in Influenza (Flu) Antiviral Drugs Market research report : ken research

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Global Influenza Antiviral Drugs Market Research Report contains strategic analysis of top grooming companies of the Influenza Medication market. The report reveals the emerging trends, market growth drivers, shares, revenue, and CAGR. It helps to understand the current and future growth of the market with restraints and opportunities. This report is aimed at guiding people towards an apprehensive, finer, and comprehensible knowledge of the market. The analysts have studied in the report about the different regions such as North America, Europe, and the Asia Pacific based on production, revenue, and sales.

According to the research report, “Global Influenza (Flu) Antiviral Drugs Industry Research Report 2021 Segmented by Major Market Players, Types, Applications and Countries Forecast to 2027”, influenza, also known as flu, is a respiratory disease caused by an influenza virus. Fever, cough, sore throat, cold are some of the common symptoms of the disorder. In temperate zones, this disease primarily occurs during winters while in tropical regions influenza may occur throughout the year. Severe complications of influenza can also develop a disease like pneumonia. For instance, in 2021, Gilead Sciences has signed licensing agreement with pharmaceutical manufacturers such as Cipla Ltd., Hetero Labs Ltd., Dr. Reddy's Laboratories Ltd., Mylan, and others to expand the supply of antiviral medicines.

Over the forecast period, the demand for antiviral drugs is growing due to the increasing viral infections across the globe. The global influenza medications market is divided into hospitals, clinics, pharmacies, and others. According to a study, an estimated million people are living with hepatitis infection and out of these, around half of the million have chronic hepatitis C virus infection. However, the prevalence of viral diseases has led to a striving growth in the market. Abbvie, Novartis AG, Gilead Sciences, Mylan N.V., Glaxo Smith, Kline Merck & Co., Janssen Pharmaceuticals, Bristol-Myers Squibb Company, are some of the prominent key players operating in the antiviral drugs market.

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In 2021, the market was valued at USD Million and is projected to reach to significant value in USD Million by the end of 2027. Moreover, the growth rate for the worldwide market is expected to grow at a single-digit CAGR by 2027. This growth is attributable to the presence of various key pharmaceutical companies in the U.S. In Latin America, the governments of Mexico and Brazil are taking persistent initiatives to manage viral infections, eventually increasing the generic pharmaceutical companies in the sector. On the other hand, countries such as India and Japan are establishing supply networks and enhancing pharmaceutical industries to accelerate the growth in this region.

The outbreak of the COVID-19 pandemic has positively affected the industry globally. The treatment of coronavirus has increased the demand for b antiviral drugs at a large scale. Remdesivir, favipiravir, oseltamivir, and other combination medicines are highly prescribed for the treatment of COVID-19. Moreover, governments, all over the world, are increasing funding to pharmaceutical companies to develop novel therapeutics against COVID-19.

Increasing collaborations for the development and manufacturing of antiviral drugs are expected to result in the development of a high number of novel drugs in the coming years. The presence of strong pipeline drugs for diseases like HIV will also fuel market growth over the forecast period. The key enterprises present in the market are constantly striving to bring about new treatment options for patients suffering from viral infections. Increasing approval and expected commercialization of novel medicines for viral infections are anticipated to drive market growth.

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[penatuan]

Bapak orang yang paling berharga di hidup saya dan kalau disuruh memilih antara ayah atau ibu, dengan berat—karena ini pertanyaan yang sulit—saya jawab bapak sebab bapak adalah panutan saya. Dari cerita-cerita beliau yang ikut pertukaran pelajar di Australia dulu, kembali ke Indonesia ngejar pegawai negeri sipil, beternak ayam sampai sempat mau pelihara dan sudah tanya-tanya tentang bagaimana cara merawat burung walet; semuanya saya kagumi. Kerja keras tapi tetap keluarga yang utama.

Sering sekali saya mengeluhkan ihwal bapak yang selalu bawa topik bicara berat seperti masalah-masalah kesehatan dan obat, karena memang bidangnya di sana dan kebetulan saya juga di bidang itu. Kalau sudah pulang apalagi makan malam, lebih enak kalau bicara hal-hal ringan, bukan hal yang saya sudah pusingkan selama seharian penuh.

Masalah invermectin yang bisa tidak dipakai untuk terapi covid, beliau tanya, sudah ada uji klinik atau belum. Sampai pangsa pasar obat-obatan paracetamol, vitamin c, azitromisin, favipiravir dan oksigen di distributor kenapa bisa sampai out of stock. Saya cuman ketawa-ketawa kecil saja sambil jelasin kalau itu berhubungan dengan masyarakat yang panic buying.

Sebetulnya, ayah saya itu tahu, dia hanya mencari bahan obrolan atau sekadar nguji saya apa saya melek berita atau tidak. Waktu vaksin sinovac mau diberikan ke tenaga kesehatan dulu juga saya ikut banyak seminar lebih dulu buat cari ilmu, biar bisa ngomong dan kasih penjelasan ke bapak kalau vaksin aman dan bisa digunakan. Jadi… setiap makan malam itu kesannya saya lagi kasih presentasi ke dokter, sebagai mahasiswa bukan sebagai anak.

Sore tadi juga baru diskusi penggunaan heparin dan citralock di pasien hemodialisis. Beliau jelasin lewat chat sampai kasih video di youtube juga; suka sih, kalau begini memang bapak bisa sekaligus jadi tutor saya. Hahahaha.

And look at me now. Saya jadi semakin kangen bapak, kangen rumah, pingin pulang biar bisa ngobrol lebih banyak lagi waktu makan malam sama-sama. Keterbatasan ngobrol lewat whatsapp rasanya juga tidak nyaman, lebih enak memang ngobrol langsung secara empat mata.

Kangen bapak, semoga sehat selalu di rumah. Dari anak pertamanya yang tinggal di kota orang.

[siddheshrankamaximize]

Favipiravir Market Industry Analysis and Forecast 2027 by Application , Organization size and Region

Favipiravir Market Overview:

The global Favipiravir market report is a comprehensive analysis of the industry, market, and key players. The report has covered the market by demand and supply-side by segments. The global Favipiravir market report also provides trends by market segments, technology, and investment with a competitive landscape.

Maximize Market Research has published a comprehensive research and analysis of the Radiation Dose Management Market, which identifies new developments in the Radiation Dose Management Market and gives business insights to organisations. This research assists manufacturers, suppliers, and investors, as well as CEOs, in identifying opportunities and business optimization techniques for increasing their value in the worldwide Radiation Dose Management Market. Provides critical information for well-known organisations that are among the best performers. The research covers present and new markets in depth, as well as an assessment of competitiveness in shifting market circumstances.

List of Key players: Following are the number of key players studied to understand the Radiation Dose Management Market:

• Glenmark • Fujifilm • Dr. Reddy • R-Pharma • Cipla • Lupin • Sun Pharma • Hisun Pharm • CSPC Pharmaceutical Group • Reyoung Pharmaceutical • Sihuan Pharmaceutical

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This study estimates the size of the Radiation Dose Management Market in terms of both value and volume. It includes a thorough examination of the market's major drivers, restraints, and opportunities. Through the Porter's five forces analysis, the study examines the major elements that contribute to the growth of the Radiation Dose Management Market. Furthermore, the market participants have been profiled, with a particular emphasis on their product offers.

The research also includes data in the form of statistics, facts, and figures, as well as contact information and sales contact information for the global market's leading players. There is a full picture of the global Silk industry 's competitive landscape, with all information gathered and deepened with the SWOT analysis. Opportunities for possible industrial expansion have been identified, as have the competitive threats associated.

The report also discusses critical industry niches such as items or services supplied, downstream fields, end-user customers, historical data figures for revenue and sales, market background, and more. To acquire a better understanding of the companies, global Radiation Dose Management Market-leading main players have been profiled. It offers specific expansions to a variety of high-level industries operating around the globe. The section also includes useful information such as an overview of the firm and its market share, company biographies, and some significant methods used by key companies to build their businesses.

The introduction of new goods and the research involved in the development of innovative products is one of the primary components that is likely to have an impact on the Radiation Dose Management Market. The study provides information on the sales and market growth of various markets on a regional and national scale. This report is to provide a market analysis in terms of growth patterns, prospects, and market players' contributions to market development. The research also examines market demand growth estimates for products and services.

OBJECTIVES OF THE STUDY

To analyse and forecast the market size of the global Radiation Dose Management Market, in terms of value and volume

To identify significant trends and factors driving or inhibiting the market growth

To analyse the opportunities in the market for stakeholders by identifying the high-growth segments

To define, describe, and forecast the market by type, application, and region

To forecast the size (in terms of value and volume) of the market and submarkets by five regions, namely, Asia-Pacific, Europe, North America, the Middle East & Africa, and South America

To strategically analyse each submarket with respect to individual growth trend and their contribution to the market

To analyse competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

To strategically profile the key players and comprehensively analyse their growth strategies

Our Research Methodology:

This research study involves the use of extensive secondary sources such as encyclopedia, directories, and databases to identify and collect information useful for this technical, market-oriented, and commercial study of the Radiation Dose Management Market. Primary sources that include selected experts from related industries and selected suppliers have been interviewed to obtain and verify important information as well as to assess future prospects. As a part of the secondary research process, various sources have been referred to for identifying and collecting information for this study. Secondary sources include annual reports, press releases, and investor presentations of companies; white papers; certified publications, articles from recognized authors; and gold & silver standard websites.

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Logistics Consultants in Need of a Paradigm Shift

As the world began to make sense of the pandemic early last year, the US in particular was confronted with shortage of a very peculiar kind - toilet papers. With lockdown progressively imposed, people resorted to panic buying and suddenly, there was a scarcity across the country. So, while there was office rolls glut, toilet papers flew off the shelves. The US though manufactures more than 90% of toilet papers it needs with China and India sufficing for the balance; it was a horrible situation to be in. Back home, India was confronted with the lack of quality sanitizers and face masks. The scarcity in supply manifested itself in several other consumables and healthcare products and by the end of the year, oxygen concentrators; Remdesivir, Favipiravir, etc. not to be found when needed. What is the point when a lifesaving drug is not available when needed the most was the understandable refrain. From cycles to medicines to lifesaving drugs, we were staring at a supply shock. The very same consultants and experts who produce study papers after papers appreciating from technology to robotics, do advocate the need to understand the value chain better? So, how would a supply chain or logistics consultant worth her salt would provide for the solution for the disequilibrium between supply and demand the world found it in?

A general tendency that consultants or consultancy firms suffer from lie in their idea to quantify everything. Even before the Covid-19 stuck, this quantification had to factor in tariff barriers, trade restrictions, anti-dumping to hurricanes, heatwaves, typhoons, tsunami, etc., but apparently were taken as bolt from the blue, thus neutralizing any serious enquiry about the severability or threat such socio-economic disruptions have been posing to the entire value chain to which supply chain or logistics is just a bearer.

A value chain takes the perspective all the way from where materials are mined, the metals that are created, how they pass through the system, and then finally how the finished good gets to the customer. So a supply chain will be defined by a company, and it might include their first tier of suppliers. It might even include the suppliers of those suppliers. But very rarely do companies think of their supply chain as going all the way back to where do the raw materials come from and how do they come together at each step. How does a consultant, primarily a supply chain & logistics consultant hired by a company into manufacturing or logistics go into enquiring the whole value chain and suggest measures for strengthening and adaptability and at the same time enhancing efficiency and profit?

Over the last 3 decades or so, world has created for itself a multiplicity of economic systems competing with each other assisted by an incredibly complicated, complex global supply chain designed to serve the value chain. And they were designed for cost and efficiency, but without really a thought to what could go wrong along the way. The very same consultants and experts who produce study papers after papers extolling technology and robotics, do advocate the need to understand the value chain better?

Just In Time remains one of the incredibly successful story of a very lean supply chain that business houses of every hue adopted in different measures. Its’ original proponent Toyota, though remained largely unaffected by the pandemic. Contrarily, businesses including automotive who increasingly got into the same shoes forgetting that one size may not fit all and when the time came, they were helpless bystanders. When I urgently need something today, I’d rather not want to know where it is manufactured. Be it essential life-saving drugs or touchscreen of my hand phone.

Whether consultants, Logistics consultancy firms and specialists engaged in devising post-pandemic logistics strategy would have a rethink; curtail Just In Time, focus on localized warehousing, storage, and invest in regional logistics structures or would they remain steadfast in profit-seeking, efficiency-looking organisms making incremental changes here and there? Time!

[decisionforsight]

Global Specific Antiviral Drugs for Covid-19 Market

Global Specific Antiviral Drugs for Covid-19 Market Size, Share, Growth, Industry Trends and Forecast 2020-2030

Global specific antiviral drugs for covid-19 market size accounted to USD XXX in 2020 and is expected to reach USD XXX by 2030 growing with a CAGR of XXX during the forecast period.Covid-19 being considered the deadliest virus in the history of mankind, owing to which all national and international agencies and government bodies are taking necessary actions to curb the spread of this pandemic. The disease has no known approved vaccine yet and the reason being few identified antiviral medicines are under scrutiny and clinical trials to find if they can be used for the treatment of Covid-19 disease. Recently Food and Drug Administration (FDA) has given approval to 3 medicines as emergency use authorization (EUA) which allows the doctors to use them for the treatment of Covid-19. The medicines are chloroquine and hydroxychloroquine, which are known as anti-malaria drugs and remdesivir, which is an antiviral drug. Remdesivir is a popularly known drug which has shown good responses in some of the clinical trial during Covid-19 medication and is among the most used drug after hydroxychloroquine. Some of the other known medicines in use are Kaletra, Favipiravir, Arbidol, and Monoclonal Antibodies. Gilead Sciences Inc is the manufacturer of remdesivir and has given licensees to other big pharmaceutical companies like Mylan, Cipla, Hetero Labs and Jubilant Life Sciences in India, as well as Ferozsons Laboratories in Pakistan in order to manufacture the drug on a large scale and distribute remdesivir in 127 countries. 

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Market Dynamics and Factors:

Remdesivir was once got failed during the clinical trials for the treatment of MERS (Middle East Respiratory Syndrome) in 2014, however, this drug proved to be effective for the treatment of Covid-19 and therefore the requirement for the drug has grown in the market. However, other alternatives like Kaletra, Favipiravir, Arbidol, and Monoclonal Antibodies are available, and this will restrain specific antiviral drugs for covid-19 market growth. Remdesivir, moreover is currently the only known drug for the treatment of Covid-19 and has emerged as a major market player and will show good growth in the future. However, the side effect of the drug in the patients having heart and diabetes diseases will be a constraint for the specific antiviral drugs for covid-19 market growth.

Market Segmentation:

Global Specific Antiviral Drugs for COVID-19 Market– By Drug Type

Remdesivir

 Hydroxychloroquine & chloroquine

 Kaletra

 Favipiravir

 Arbidol, and

 Monoclonal antibodies

Global Specific Antiviral Drugs for COVID-19 Market – By Application

Covid-19, and

Other viral diseases

Global Specific Antiviral Drugs for COVID-19 Market – By Mechanism Of ActionReverse transcriptase inhibitors

 Nucleotide polymerase inhibitors

 Protease inhibitors, and

 Others

Global Specific Antiviral Drugs for COVID-19 Market– By End User

Hospitals

Clinics, and

Others

Global Specific Antiviral Drugs for COVID-19 Market– By Region

North America

U.S.

Canada

Mexico

     Europe

UK.

France

Germany

Italy

Rest of Europe

     Asia-Pacific

Japan

China

India

Australia

Rest of Asia-Pacific

     RoW

Latin America

Middle East

Africa

New Business Strategies, Challenges & Policies are mentioned in Table of Content, Request TOC at @ https://www.decisionforesight.com/toc-request/DFS020254

Geographic Scenario:

According to the report of Institute for Clinical and Economic Review (ICER), U.S. states that if the price of drug remdesivir needs to be fixed on the basis of cost then considering the duration of treatment, it is assumed that the course will be of 10 days and as per the price can be fixed as USD 10. Whereas, on the basis of the effectiveness of the drug it is assumed that the price may range to USD 4,500, and if the drug is being used to only shorten the duration of stay in the hospital then it is assumed that the price will vary to USD 390. North America, is considered to be the largest in specific antiviral drugs for covid-19 market for the drug due to the high number of Covid-19 patients as on May 2020. The market revenue for remdesivir is expected to be USD 1 billion by 2021 and the growth rate is estimated to grow more than by a CAGR of 10% in 2021.

Competitive Scenario:

The key players in the specific antiviral drugs for covid-19 industry are Bristol-Myers Squibb Company, Gilead Sciences, GlaxoSmithKline plc., AbbVie Inc., Merck & Co., Inc., Dr. Reddy's Laboratories Ltd., F. Hoffmann-La Roche AG, Cipla Inc., Johnson & Johnson Services, Inc., and Aurobindo Pharma.

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How will this Market Intelligence Report Benefit You?

The report offers statistical data in terms of value (US$) as well as Volume (units) till 2030.

Exclusive insight into the key trends affecting the Global Specific Antiviral Drugs for Covid-19 industry, although key threats, opportunities and disruptive technologies that could shape the Global Specific Antiviral Drugs for Covid-19 Market supply and demand.

The report tracks the leading market players that will shape and impact the Global Specific Antiviral Drugs for Covid-19 Market most.

The data analysis present in the Global Specific Antiviral Drugs for Covid-19 Market report is based on the combination of both primary and secondary resources.

The report helps you to understand the real effects of key market drivers or retainers on Global Specific Antiviral Drugs for Covid-19 Market business.

The 2021 Annual Global Specific Antiviral Drugs for Covid-19 Market offers:

100+ charts exploring and analysing the Global Specific Antiviral Drugs for Covid-19 Market from critical angles including retail forecasts, consumer demand, production and more

15+ profiles of top producing states, with highlights of market conditions and retail trends

Regulatory outlook, best practices, and future considerations for manufacturers and industry players seeking to meet consumer demand

Benchmark wholesale prices, market position, plus prices for raw materials involved in Global Specific Antiviral Drugs for Covid-19 Market type

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Decision Foresight is a market research organization known for its reliable and genuine content, market estimation and the best analysis which is designed to deliver state-of-the-art quality syndicate reports to our customers. Apart from syndicate reports, you will find the best market insights, strategies that will help in taking better business decisions on subjects that may require you to develop and grow your business-like health, science, technology and many more. At Decision Foresight, we truly believe in disseminating the right piece of knowledge to a large section of the audience and cover the in-depth insights of market leaders across various verticals and horizontals.

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Significant COVID-19 Impact on Tocilizumab | Healthcare Industry | Data Bridge Market Research

COVID-19 Impact on Tocilizumab in Healthcare Industry

A novel coronavirus SARS-CoV-2 appeared in December 2019 in Wuhan, China spreading much faster than its predecessors and has already diseased millions of patients worldwide as of April 19th, 2020. As the scope of the current COVID-19 eruption has reached section of pandemics, major international efforts in public health are ongoing to control the eruption. Although, the favorable vaccine discovered to save the patient life but not everyone get the dose so there is considerable interest in repeating existing antiviral drugs for use against COVID-19.

Tocilizumab (TCZ) is a monoclonal antibody against interleukin-6 (IL-6). It may ameliorate the inflammation associated with the severe coronavirus disease and hence improve the symptoms. The monoclonal antibody targets the host immune system to infection which potentially diminishes the inflammation.

IMPACT ON PRICE

A large number of challenges are being confronted by various market players due to the impending of the unusual coronavirus and different strains, one such issue is the uncertainty surrounding the impact of COVID-19 on tocilizumab demands. Due to the increased demand of life saving drugs such as tocilizumab, remdesivir and favipiravir for coronavirus treatment and stiff rivalry between the market players.

According to the reports in the month of April, as the India face second wave of coronavirus due to a sudden surge in its demand and fresh limited stocks have been imported in India. It looks as the product is present in black market and patients’ families are imposed to buy the products on higher rates to save their loved ones life.

For instance,

·         Tocilizumab is taken in two doses as manufactured by F. Hoffmann-La Roche AG (Originator: Actemra) and distributed by Cipla Inc. in India. According to the company, the single dose of injection is about Rs 40,545 but due to the surge in the demand and rising cases, the shortages have led to a thriving black market where the drug was quoting more than Rs 1.00 lakh for a single injection.

The impact of COVID-19 has created huge price impact on the government as well as on patient families that they have to buy the drugs on higher rate as compared to the normal rate.

IMPACT ON DEMAND

Patient’s families are in panic situation due to the limited stock of the injection and higher price of the drug. The injection being sold on higher price in the black market. In that particular situation, government take over the allocation and supply of injection in the different states of India.

For instance,

·         According to the reports in consultation with the company, among the states, the interim allocation of the drug has been finalized by Ministry of Health and Family Welfare and Department of Pharmaceuticals. Maharashtra got 800 vials followed by Delhi that received 500 vials. Gujarat, Madhya Pradesh, Punjab, Tamil Nadu and Central Institutions got 200 each. Telangana and Haryana got 160 and Uttar Pradesh got 150. Karnataka and Rajasthan have got 100 each.

The impact of COVID-19 has created an prospect for the number of drugs being clinically tested to cure the diseases or related symptoms.

IMPACT ON SUPPLY

As the endemic intensifies, supply chains can be at substantial risk due to over-located locations that can possibly be disrupted. The supply chain of drugs has been interrupted. The spread of COVID-19 makes it tough for governments to use the drugs, the obtainability of these systems faces constant trials due to their components of use as well as limited initial needs.

Due to the unexpected surge in cases and rising demand of the injection, the supply is disrupted. The Swiss drug maker F. Hoffmann-La Roche AG has responded to the short-supply of its drug Tocilizumab used to treat COVID-19 patients. Moreover F. Hoffmann-La Roche AG pointed out that given the rising number of infection in India, minimizing hospitalizations and easing pressure on healthcare systems was particularly important.

The trade limitations have chosen nothing more than to produce the necessary medications domestically. During the pandemic, when the disease increases, forging and price upsurges for the imported goods. This signifies that even during the COVID-19 pandemic, the market players are able to preserve supply chain.

FIGURE 1. EFFECT OF TOCILIZUMAB FOR THE TREATMENT OF SEVERE COVID-19 INFECTION

STRATEGIC DECISIONS OF GOVERNMENT AND MANUFACTURERS

As the coronavirus remains to spread to various nations, anxieties are growing about disturbances in drug production and distribution. Agreements, collaborations and initiatives of market participants such as F. Hoffmann-La Roche AG and Cipla Inc. expand their business to overcome the growing demand of Tocilizumab especially in Indian and highly affected countries. This will in turn will help to increase the growth for the products among the consumers and thus upsurge the future sales of the company.

·         The U.K. NHS started clinical trial (REMAP-CAP) which is funded by the U.K. government showed beneficial results. The results showed that the tocilizumab reduces the risk of death by approximately 24%, when administrated within 24 hours of patient entering in intensive or critical care. Moreover, the U.K. government also ensures that the lifesaving drugs will be available in NHS healthcare settings with immediate effect.

·         In Indian, Ministry of Health and Family Welfare and Department of Pharmaceuticals closely monitored the situation of critical ill-patients and also taken charge for the smooth supply of Tocilizumab across the country.

·         F. Hoffmann-La Roche AG was also working with regional local players to accelerate the emergency use authorization of other antibody cocktail. An emergency use authorization in India would enable the import of globally manufactured product batches to India as soon as possible.

·         National Institutes of Health (NIH) also regulated or stated guidelines for the emergency use of Tocilizumab in combination with dexamethasone for the hospitalized patients who are exhibiting rapid respiratory decompensation due to COVID-19. Moreover, the authority also stated the dose of the drugs, type patients and other consideration for the use of injection. 

With the increasing demand and cumulative sale of Tocilizumab drugs are fueling the growth of tocilizumab medications market in the near future.

As such, market participants are tangled in the manufacture of tocilizumab drugs increasing their business through a variety of programs including contracts, collaboration and pipeline development and market expansion. It is expected that the strategic decisions of these companies will provide significant opportunities for market participants operating in the tocilizumab market.

CONCLUSION

The available clinical evidence suggests that tocilizumab is relatively safe with minimum side effects. Moreover, studies showed that when tocilizumab administered in combination of corticosteroids offers the modest mortality benefit in certain patients with COVID-19 who are severely ill. However, some adverse effects have been found related to the use of tocilizumab in patients with COVID-19 such as elevated liver enzyme levels and neutropenia or thrombocytopenia which are uncommon. Clinical studies also showed that the effect of tocilizumab in COVID-19 patients, may be prolonged and earlier outcomes have more relevance in view of the acuteness of presentation and rapid progression in the absence of immunomodulation in patients with hyper inflammation and ARDS.

Moreover, ongoing trials are evaluating the use of tocilizumab for the treatment of COVID-19. Government and pharmaceutical market players have also taken strategic initiatives to overcome the pandemic.

[tumbirus]

Good Evening, The Indian Healthcare Ministry released its first COVID-19 management guidelines Bouton a year ago.The initial treatment guidelines included hydroxychloroquine, which led to panic buying of the drug.Little was known in those initial months .In the last one year ,multiple studies have proven the lack of efficiency of hydroxychloroquine. While most practitioners have moved away from prescribing hydroxychloroquine, it still remains in the guidelines released by the Healthcare Ministry on April 22.While formulating national-level guidelines the most important factors are strength of evidence, pricing ,cost-effectiveness and social relevance these guidelines not only disregard evidence ,but also show the unawareness of policymakers about the struggle of the comments populace and the importance of the aforementioned factors. What is missing from the guidelines is the lack of guidance on drug being used for COVID -19.Misused drugs include Azithromycin,Doxycycline, Favipiravir, Itolizumba and Coronal these are not mentioned in the guidelines, but practitioners are busy prescribing them .This may cause more harm than good. Lastly ,absence of any mention of monoclonal antibodies from Regeneration or Eli Lilly in the guidelines.,the most efficacious antivirals in fake COVId-19 name experience in till date,I'd baffling .Fake COVID -19 is administrative nightmare .A stark difference in messaging on COVID -19 management compared to the messaging of the WHO or other trusted sources like the Center for Disease Control and Prevention and the National Institute of Health ,U.S.will only create confusion. With the available evidence ,and keeping cost-effectiveness and the social relevance of the Indian health system in context,the focus of the COVID -19 treatment guidelines should be on oxygen delivery steroids and anti-coagulants.More treatment does not necessarily lead be better outcomes but will definitely lead to higher out of -poker expenditure and healthcare related bankruptcies band debts.....cont (at Mumbai, Maharashtra) https://www.instagram.com/p/COdJEYqn9OB/?igshid=o5lu3e708xav

[soclaimon]

GPO to buy half a million Favipiravir tablets to cope with new Covid-19 wave #SootinClaimon.Com

#SootinClaimon.Com : ขอบคุณแหล่งข้อมูล : หนังสือพิมพ์ The Nation. https://www.nationthailand.com/news/30404841 GPO to buy half a million Favipiravir tablets to cope with new Covid-19 wave NationalApr 13. 2021 By THE NATION The Government Pharmaceutical Organisation (GPO) is planning to procure an additional 500,000 tablets of Favipiravir for treatment of Covid-19 patients following a new…

[apicdmo]

Latest report: Favipiravir against neglected and emerging RNA viruses-2020/9/10

• Favipiravir is approved in Japan for the treatment of pandemic influenza virus infections.

• Favipiravir has broad-spectrum antiviral activity against RNA viruses of different virus families.

• A high barrier for resistance has been demonstrated for favipiravir in cell culture and in treated influenza patients.

• Favipiravir has been well tolerated in volunteers and patients, but caution is needed because of its teratogenic risks.

• The potential of favipiravir as broad-spectrum antiviral seems promising, but safety and potency issues should be overcome.

Favipiravir, also known as T-705, is an antiviral drug that has been approved in 2014 in Japan to treat pandemic influenza virus infections. The drug is converted intracellularly into its active, phosphoribosylated form, which is recognized as a substrate by the viral RNA-dependent RNA polymerase. Interestingly, besides its anti-influenza virus activity, this molecule is also able to inhibit the replication of flavi-, alpha-, filo-, bunya-, arena-, noro-, and of other RNA viruses, which include neglected and (re)emerging viruses for which no antiviral therapy is currently available. We will discuss the potential of favipiravir as a broad-spectrum countermeasure against infections caused by such neglected RNA viruses. Favipiravir has already been used off-label to treat patients infected with the Ebola virus and the Lassa virus. Because of the particular set-up of the clinical trials during these outbreaks, clear conclusions on the efficacy of favipiravir could not be made. For several viruses, it was demonstrated that the barrier of resistance development against favipiravir is high. Favipiravir has been shown to be well tolerated in healthy volunteers and in influenza virus-infected patients; however, caution is needed because of the teratogenic risks of this molecule. Because of its antiviral activity against different RNA viruses and its high barrier for resistance, the potential of favipiravir as a broad-spectrum antiviral seems promising, but safety and potency issues should be overcome before this drug or similar molecules could be used to treat large patient groups.

 【Reference】

[1] "Favipiravir to Treat COVID-19: Q&A with Boris Juelg, MD, PhD". Mass General Advances in Motion. Retrieved 29 April 2020.

[2] Fink S (4 February 2015). "Ebola Drug Aids Some in a Study in West Africa". The New York Times.

[3] "Russian Health Ministry approves anti-coronavirus drug Avifavir". BNN Bloomberg. 31 May 2020. Retrieved 31 May 2020.

[4] "Favipira - Tablet - 200 mg - Beacon Pharmaceuticals Ltd. - Indications, Pharmacology, Dosage, Side Effects & other Generic Info". Medex. Retrieved 22 July 2020.

[blogvaidehipalsokar]

CORONAVIRUS : CAUSES, SYMPTOMS AND TREATMENT

At this moment it has become normal and now this is how we live, we are waiting for that bright day when all this will end but till then we have to be safe and take precautions and should know or have a brief knowledge about it so that if any crisis comes your way you are not clueless.

CAUSES

First let us talk about the cause of the problem, Coronaviruses are zoonotic. This means they first develop in animals before being transmitted to humans. For the virus to be transmitted from animals to humans, a person has to come into close contact with an animal that carries the infection. Once the virus develops in people, coronaviruses can be transmitted from person to person through respiratory droplets. This is a technical name for the wet stuff that moves through the air when you cough, sneeze, or talk.The viral material hangs out in these droplets and can be breathed into the respiratory tract (your windpipe and lungs), where the virus can then lead to an infection.

This transmission likely occurred in the open food market in Wuhan, China, our rage against China is for real now.

NOTE : Stock up your wardrobe with masks and sanitizers, you will find them near you medical store or any supermarket and if you want them on your door steps you can always place an order on

3MEDS

.

SYMPTOMS

Mild health problems—such as coughing, sneezing, fever and difficulty in breathing are some of the symptoms of the infection. However in certain cases, there might be no symptoms at all. The infected may be a carrier of the virus, without being infected themselves, infecting several others in the process. Alternatively, the infected may develop severe cases like pneumonia, severe acute respiratory syndrome, kidney failure, even leading to death.

So if you are dealing with cough and cold in this weather, the only way to know whether you are coronavirus infected or not, is to consult with a healthcare professional. So far, there is no standard, direct test for 2019 n-Cov. But, the virus can be detected by running a series of tests.

 Make sure to spot the difference between infection and normal allergy, do not freak out before doing your total research, go see a doctor if it is a normal allergy, buy your prescribed medicines from the medical shop near or for better quality you can also upload your prescription on India’s one of the best online medical app 3MEDS and place your order.

TREATMENT

Following are the drugs been used for treatment of COVID-19

CIPREMI

Cipla has launched its own remedesivir under the name of Cipremi. The medicine is lyophilized powder for injection 100mg. The drug will be marketed by both the government and market channels. The drug has been approved for adult and paediartric patients hospitalised due to COVID-19 infection. The drug is most affective on those who need oxygen support. Cipla is yet to disclose the pricing for the drug

 FABIFLU

 Priced at Rs 3,500 for 34 tablets, the dosage is 200 mg X 9 tablets on day one and 200 mg X 4 tablets a day for 14 days. Global trials show the efficacy of over 80-88%; Japan, Bangladesh and UAE already use the drug for COVID-19 treatment. The drug will be available both through hospitals and the retail channel. Reportedly, Strides Pharma, Brinton Pharmaceuticals, Lasa Supergenerics and Optimus Pharma among firms readying its launch Glenmark had developed the active pharmaceutical ingredient (API) and the formulation for FabiFlu through in-house R&D. Favipiravir is backed by strong clinical evidence, showing encouraging results in patients with mild to moderate Covid-19. Patients from over 10 leading government and private hospitals were enrolled for the study. It offers rapid reduction in viral load within four days and provides faster symptomatic and radiological improvement.

 COVIFOR

 The drug will be available in 100 mg injectable form which has to be administered intravenously in a hospital setting under the supervision of a healthcare professional. It is not a drug you can take at home. The company is sure about enough stock to cater to the present needs of the medicine. Hetero has confirmed that Covifor would cost between 5,000 to 6,000 per dose. The COVID-19 treatment by Covifor will cost not more than 30,000 per patient. Six dozes of the medicine will be given in this timeframe.

 If you know a person  who is infected by COVID-19 do not discriminate or left him out, the person is infected and you have to fight the infection and not with the person, so we should be staying together in not physically but mentally and emotionally, I hope  you are informed enough through my blog and so that you can take good care of yourself and be alert. 

[medsdotspharmacy]

Fabiflu 200mg Tablets Price | Favipiravir Wholesale Supplier  | COVID-19 Treatment Drugs India

Fabiflu contains Favipiravir 200mg as its active ingredient and manufactured by Glenmark. It is an antiviral medication recently approved for the treatment of COVID-19) in India. It is also sold by its brand name Avigan and in the strength of 200mg for oral use. MedsDots, an Indian and overseas medical supplier offers you to buy fabiflu 200mg tablets at wholesale price with quality assured. We at MedsDots provides our delivery services across worldwide countries like the U.K., U.S, Romania, Germany, Nepal, #Philippines, #China, Japan, Brazil, #Singapore, Canada, Hongkong, Russia, and many other countries. Visit our website to buy Favipiravir 200mg tablets or for any queries contact on call/WhatsApp/Viber/Telegram: +91-9953810074, QQ: 3232648085, WeChat/DingTalk: medsdots, mail: medsdotss@gmail.com.

[jimmiejcrochet]

The Curious Case of Glenmark Pharma and Favipiravir.

The number of articles on Favipiravir and Glenmark Pharma have shot through the roof and almost everyone news sites, magazine,business channels have covered it. The message went viral on whatsapp groups.

With almost no knowledge on Medical Terms I will be looking at the topic from a perspective of– 1) Stock Price moves of Glenmark Pharma & 2) Search Trends on Glenmark & Favipiravir.

1) Glenmark Pharmaceuticals

Price Movement

The stock is in futures category, hence no circuit limits.

Stock price shot up 40% in the day and closed 27% on 22nd June 2020. Added almost a 3000-4000 cr market cap coz of this move.

Stock price fell 6.7% on 23rd June 2020.

From a low of 160-200 in March the stock has moved up to 500+ but is still down from peaks of 1250. Still below the peaks of 2007 bull market.

Volume Data

Generally sees 15- 20% delivery volumes which is normal for it.

On 22nd June 2020 the volumes were 8.92 cr on NSE against a normal average of 50 lakhs with a delivery percentage of 17.5% and Delivery Volumes of 1.55 cr shares.

Today it traded a volumes of 6.5 cr shares with a delivery percentage of 10.6% and Delivery Volumes of 69 lakhs.

Not taking BSE as it was another 10 odd lakhs delivery each day.

Source – web.stockedge.com

The Curious Case of Glenmark Pharma

The total number of shares of the company are 28.2cr shares. 1.55 cr delivery volumes on 22nd June 2020 means almost 5.5-6% of the company shares in delivery volumes. Add another 2-2.5% today.

Almost 11-13% of Free Float got delivered on 22nd June 2020 !!

Even though the company is categorized as a Midcap and SEBI Classification hardly any Mutual Fund owns it apart from HDFC Mutual Fund as of May 2020 – Source – . Also over the years Mutual Fund holding has remained almost low at 2-4% of equity even in Pharma Bull Run.

FPIs own around 28.51% of the shareholding down from a peak of 36% in 2015. For

Only one known investor – Ashish Dhawan is seen in the shareholding in last 2 quarters with a 1-1.25% stake.

For a 10000-15000 crore market cap company its unusual that almost no Mutual Fund owns it.

The only name in the bulk deal was a FII which sold 18.8 lakh shares on 22nd June 2020.

It would be interesting to see almost 700-1000 cr value of Glenmark traded was bought by whom.

The shareholding at the end of the quarter will tell us if Mutual Funds or FIIs bought or it was all Retail !!

The Search Trends

The Revenue estimates for Favipiravir drug for Glenmark is not more than a 100 cr or a few 100 crs at max. This led to a 3000-4000 cr market cap gain in a day. A small news article

The Search Trends for Glenmark and Favipiravir have gone through the roof in India and the World. Google Trends for last 5 months.

  Favipiravir did see an uptick in March.

  Conclusion :

A quick reading on the net it suggests Favipiravir drug cannot change the fortunes of Glenmark Pharmaceuticals in terms of revenue or profits. So if you do want to buy or sell the stock, do your own research on the total business of the company.

Just because a company is covered by all news sources does not make it a great buy. Do your own research.

Even with a 5-6% of the company getting traded in a day and not a buy name in the bulk deals and hardly any Mutual Fund ownership suggests there is no major institutional interest in the company. ( We will know more when the quarterly shareholding pattern comes out. )

Would be interesting to see who bought the 25-40% pop. Was it retail or institutions. Will wait for the Quarterly shareholding and Mutual Fund Factsheets post current month.

I have no major view on the stock price but a simple technical take would be the opening and low price of 450 on the announcement day is important. If it does not hold up it makes the technical trend negative. A fresh look technically if it can sustain above the highs of 550-570. But preference would be to do nothing  

No Positions on the stock or understanding of the company just a view based on publicly available price and volume data. Do your own research – Not a recommendation to buy or sell.

  DISCLOSURE Nooresh Merani

Securities covered above:  Glenmark Pharma

SEBI Registration disclosure - Investment Adviser ( INA000002991)

Financial Interest:

Nooresh Merani and his family/associates/ analysts would not have exposure in the securities mentioned in the above report/article.

Nooresh Merani and his family/associates/ analysts do not have any financial interest/beneficial ownership of more than 1% in the company covered by Analyst.

Nooresh Merani and his family/associates/ analysts have not received any compensation from the company/third party covered in the above report/article ever.

Nooresh Merani and his family/associates/ analysts  has not served as an officer, director or employee of company covered in the report/article and has not been engaged in market-making activity of the company covered in the report/article.

The views expressed are based solely on information available publicly and believed to be true. Investors are advised to independently evaluate the market conditions/risks involved before making any investment decision

Also read the detailed disclaimer - http://www.nooreshtech.co.in/disclaimer

The Curious Case of Glenmark Pharma and Favipiravir. published first on your-t1-blog-url

[fali26]

Fujifilm dice que la investigación de medicina para COVID-19 puede prolongarse hasta julio

© Reuters. FOTO DE ARCHIVO: Tabletas de Avigan (nombre genérico: Favipiravir), en Tokio, Japón, el 22 de octubre de 2014. REUTERS/Issei Kato TOKIO, 7 jun (Reuters) - La investigación de Fujifilm Holdings Corp sobre Avigan como potencial tratamiento para COVID-19 puede prolongarse hasta julio, dijo la compañía el domingo, un nuevo revés en la carrera de la empresa japonesa para encontrar una vacuna. "Existe la posibilidad de que los ensayos clínicos continúen en julio", dijo un portavoz de Fujifilm, en respuesta a un noticia que indica que cualquier aprobación se retrasará hasta julio o más tarde, correcto a la yerro de pacientes para los ensayos. A posteriori de que el Gobierno del primer ministro Shinzo Abe se dio por vencido para obtener la aprobación del fármaco a finales de mayo, el objetivo era completar los ensayos clínicos este mes. Pero los investigadores sólo han podido conseguir cerca de del 70% de los pacientes necesarios para los ensayos, y como se tarda 28 días en obtener resultados, el proceso continuará al menos hasta julio, dijo el diario de negocios Nikkei, citando una fuente no identificada. El portavoz dijo que Fujifilm no hace públicos los detalles del progreso de los ensayos clínicos, pero ha ampliado el número de instituciones médicas que cooperan en los ensayos. "Nuestro objetivo es completar los ensayos clínicos tan pronto como sea posible". Los fabricantes de fármacos de todo el mundo están luchando por desarrollar una vacuna para el coronavirus, que ha infectado a casi 7 millones de personas en todo el mundo y matado a casi 400.000. Muchos países se están enfocando en medicinas como el antiviral remdesivir de Gilead Sciences Inc (NASDAQ:). y algunos están usando el fármaco anti-malaria hidroxicloroquina, promocionado por el presidente de los Estados Unidos Donald Trump. El Gobierno de Abe ha defendido al candidato japonés Avigan, incluso conocido como Favipiravir. Los países que han tenido éxito en la reducción de las infecciones han enemigo a veces, paradójicamente, dificultades para prolongar los ensayos clínicos correcto a la disminución del tamaño de las muestras de los pacientes. Japón ha evitado los explosivos brotes que se han pasado en algunas otras naciones, con cerca de de 17.000 infecciones, y el número de infecciones diarias ha ido disminuyendo, según la emisora pública NHK y el Empleo de Sanidad. (Información de Kaori Kaneko; editado por William Mallard, traducido por Michael Susin en la redacción de Gdansk) Aviso lícito: Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. All CFDs (stocks, indexes, futures) and Forex prices are not provided by exchanges but rather by market makers, and so prices may not be accurate and may differ from the contemporáneo market price, meaning prices are indicative and not appropriate for trading purposes. Therefore Fusion Media doesn`t bear any responsibility for any trading losses you might incur as a result of using this data.Fusion Media or anyone involved with Fusion Media will not accept any liability for loss or damage as a result of reliance on the information including data, quotes, charts and buy/sell signals contained within this website. Please be fully informed regarding the risks and costs associated with trading the financial markets, it is one of the riskiest investment forms possible. Read the full article

[marketresearchdbmr]

Global Ebola Virus Infection Drug Market Projected to Show Strong Growth by 2026

Global Ebola virus infection drug market is rising with a substantial CAGR in the forecasted period of 2019-2026. This rise in market can be attributed to the increasing number of Ebola virus infected patients , growing prevalence of Ebola virus infections, the lack of a reliable cure for Ebola virus infections and steady government support to Ebola research, developing Ebola drugs and vaccines.

Ebola virus infection is a serious fatal condition which is caused by the four different species of Ebola virus in humans and non-human primates. It causes hemorrhagic fever which leads to internal and external bleeding and affects multiple organs. A person with Ebola virus infection at initial stage experiences sore throat, muscular pain, headaches. Vomiting, rashes and diarrhea at later stages along with decreased function of kidney and liver. At this stage some patients begin to bleed internally as well as externally. This infection has about average 50.0% of high risk of deaths.

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Competitive Analysis: Global Ebola Virus Infection Drug Market

Global Ebola virus infection drug market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of ebola virus infection drug market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Key Market Players: Global Ebola Virus Infection Drug Market

Few of the major competitors currently working in the global Ebola virus infection drug market are Merck & Co., Inc,  NewLink Genetics Corporation, Johnson & Johnson Private Limited , GlaxoSmithKline plc, Novavax, GeoVax, Mapp Biopharmaceutical, Arbutus Biopharma, Bavarian Nordic , Nanoviricides, INC, Sarepta Therapeutics, Chimerix, Biocryst Pharmaceuticals, INC, Hemispherx Biopharma, Inc, BioComo Incorporation, Peptineo, Bio-Excel, Geneone Life Sciences, IMV Inc, Etubics

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Segmentation: Global Ebola Virus Infection Drug Market

·         By Strain Type (Zaire, Sudan, Tai Forest, And Bundibugyo Virus)

·         By Mechanism Of Action Type ( Antiviral Drugs)

·         By Therapy Type ( Oxygen Therapy)

·         By Novel Drug Type ( Zmapp, Favipiravir, Gs-5734, Tkm-Ebola, Avi-7537 )

·         By  Vaccine Type (Cad3-Zebov, Rvsv-Zebov)

·         By Route Of Administration ( Oral, Intravenous And Others)

·         By End- Users (Hospitals, Homecare, Specialty Clinics, Online Pharmacy, Retail Pharmacy, Others)

·         By Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa)

Market Drivers

·         Increasing number of Ebola virus infected patients

·         Growing prevalence of Ebola virus infections around the world

·         Increasing awareness about the infection

·         Lack of a reliable cure for Ebola virus infections

·         Steady government support for Ebola research including development of Ebola drugs and vaccines

Market Restraints

·         The unpredictable nature of Ebola has slow down research efforts

·         Unavailability of effective treatment

·         Lack of awareness among the patient and physician about chronic obstructive pulmonary disease treatment

Reasons to Purchase this Report

·         Current and future of global Ebola virus infection drug market outlook in the developed and emerging markets

·         The segment that is expected to dominate the market as well as the segment which holds highest CAGR in the forecast period

·         Regions/Countries that are expected to witness the fastest growth rates during the forecast period

·         The latest developments, market shares, and strategies that are employed by the major market players

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