#blackfan

[leoparditattoo]

F Ä C H E R & F I L L E R 🐜danke Johanna 💚 @johannamariee_ / / #leoparditattoo #studiomonochrom #kölntattoo #monochromkoeln #leoparditattoo #studiomonochromkoeln #leoparditattoocologne #tattooshopcologne #tattoostudiokoeln #kölntattoo #colognetattoos #colognetattoo #colognetattooartist #blacktattoos #blacktattooartist #blackworkers #fantattoo #japanesefantattoo #finelinetattoo #finelinefan #blackfan #fillertattoos (hier: Cologne (Köln), Germany) https://www.instagram.com/p/CoR7DaAMD3b/?igshid=NGJjMDIxMWI=

[regenhealthsolutions]

An Universal Gene Therapy for Diamond-Blackfan Anemia Is Poised for Clinical Trials

Treatment designed to work across different genetic mutations At a glance: A new gene therapy is designed to treat the life-threatening disorder no matter which specific genetic mutation a patient has. The therapy is ready to test in clinical trials. Work offers proof of concept that gene therapies can treat disease by targeting a shared problem that various individual mutations lead…

[futuremarketshubham]

Global Diamond-Blackfan Anemia (DBAAASE) Syndrome Therapeutics Market Explosive Growth Forecasted at 4.2% CAGR from 2023 to 2033

The global Diamond-Blackfan Anemia (DBAAASE) Syndrome Therapeutics Market is predicted to exceed an impressive US$ 4.8 Billion in 2023, with a compound annual growth rate (CAGR) of 4.2% from 2023 to 2033. The global Diamond–Blackfan Anemia (DBAAASE) Syndrome Therapeutics market is expected to garner a market value of US$ 7.29 Billion by 2033.

Because 90% of infected individuals develop hematologic difficulties during their first year of life, a rise in the incidence of blood disorders catapulted the global diamond-blackfan anemia treatment market over the historical era. Moreover, growing government R&D support, changing lifestyles, and rapidly evolving technology are anticipated to propel market growth in the forecast period.

North America dominates the diamond-blackfan anaemia syndrome therapeutics market owing to the presence of major notable stakeholders, high expendable income, increased medical costs, and an established medical sector in this region. According to a report published by Clevel and Clinic, the DBA Registry of North America, a database containing data on people who have this disorder, 25% of people with DBA die before the age of 50 from affiliated medical disorders.

Download Sample Report to learn about recent in the Dengue Fever Treatment Market by FMI @ https://www.futuremarketinsights.com/reports/sample/rep-gb-16433

DBA UK is a registered charity (1083179) that is governed by a written constitution and run by appointed volunteer groups. They offer support, research, and hope to the DBA community by bringing families together to discuss their experiences, share the most recent health history, and raise funds to assist those with DBA in the United Kingdom.

Key Takeaways from the Market Study

Global DBAAASE syndrome therapeutics market to expand 1.5x from 2023 to 2033

By treatment, blood transfusions to experience a growth rate of 6.9%

Around 2 out of 5 DBAAASE syndrome therapeutics to happen across North America

Europe to emerge as an important contributor, expected to surge at a CAGR of 3.7%

Treatment through corticosteroids to gain equal traction as blood transfusions

“As medical science expands, treatments and therapies for a broad range of blood disorders is gaining major traction. This is boding well for the market on diamond blackfan anemia syndrome, with healthcare providers introducing a plethora of therapies and treatment approaches,” says an FMI analyst.

Key Companies Profiled

Sumitomo Corporation

Johnson & Johnson Private Limited

Novartis AG

Pfizer Inc.

Sanofi S.A

Merck & Co. Inc.

LEO Pharma A/S

Cipla Limited

GSK Plc.

AstraZeneca Plc.

Abbott Laboratories

Bayer AG

Key Segments Profiled in the Diamond–Blackfan Anemia (DBAAASE) Syndrome Therapeutics Market Industry Survey 

By Treatment:

Corticosteroids

Chelation Therapy

Blood Transfusions

Stem Cell Transplant

Others

By End User:

Hospitals

Clinics

Others

By Region:

North America

Europe

Asia Pacific

Latin America

Middle East and Africa

About Future Market Insights (FMI)

Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a vast team of over 5000 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.

[medicaregate]

Diamond Blackfan Anemia | Causes, Diagnosis and Treatments

Diamond Blackfan anemia (DBA) is a form of congenital anemia that is characterized by pure red cell aplasia and is related to congenital bone abnormalities.

It is a type of macrocytic-normocytic anemia that is chronic.

Diamond Blackfan anemia develops as a result of a genetic mutation.

The most common mutation affects a ribosomal protein on chromosome 11. However, newer studies have discovered mutations in the transcription factor GATA1.

Diamond Blackfan anemia is a very rare disease that affects 1 in 500000 live births. In most cases, onset occurs within the first year of life.

Patients with Diamond Blackfan anemia are highly susceptible to hematological complications in the first year of life.

Diamond Blackfan anemia appears in 90% of patients before the age of 12 months.

Congenital bony malformations account for 50% of cases, and growth retardation accounts for 30%.

The median age of the patient at presentation and diagnosis is two months.

Children typically first exhibit pallor and lethargy.

The first-line therapy for Diamond Blackfan anemia is corticosteroids. However, patients with DBA frequently need ongoing blood transfusions and concurrent iron chelation therapy because of the long-term side effects of corticosteroids.

When steroid therapy is effective but the side effects are intolerable, the patient will need chronic blood transfusions.

Hematopoietic stem cell transplants (HSCT) may also be used to treat DBA.

Recent literature suggests that gene therapy and gene editing may be used to treat DBA in the future.

Read more at: https://medicaregate.com/diamond-blackfan-anemia-causes-diagnosis-and-treatments/

[transhells]

Trans fanconi anemia: A transabled ID where you feel you are meant to have fanconi anemia.

Trans diamond-blackfan anemia: A transabled ID where you feel you to have diamond-blackfan anemia.

Trans hemolytic anemia: A transabled ID where you feel you are meant to have hemolytic anemia.

Trans aplastic anemia: A transabled ID where you feel you are meant to have aplastic anemia.

Trans autoimmune hemolytic anemia: A transabled ID where you feel you are meant to have autoimmune hemolytic anemia.

[tapwater118]

Any thoughts on blackfan (black hole x fanny)… or treefan mayhaps…

blackfan i see more as friends more than anything. its mostly fanny, i think she would be overly selective of life partners

treefan had like a one night hookup cause even tho fanny’s a lesbian tree is gnc af so they were both curious if anything was there. there wasn’t, but they both consider it a valuable learning experience and are still friends

👁️ out of 🫵

[euphoriaemporiae]

@lungsandlips

[blackfane] liked [kadeconroy]'s photo. [blackfane] liked [kadeconroy]'s photo. [blackfane] liked [kadeconroy]'s photo.

[destinyc1020]

I see where the anon is coming from, not in the sense of the same actors being "recycled" but when a white actor is in something that people love they almost instantly become famous whereas if someone was POC they dont get that same treatment, they are almost sidelined or subjected to racism and harrassment so visibility is almost a double edged sword for POC actors especially black actresses.

Yeah its an issue in fandoms, racism and in general the erasure of fans of color tends be a significant problem not to say they dont exist, they do. I agree from my perspective like we love our artists down, but we also tend to keep it in our community as well, like growing up we knew jaime foxx, tyra, denzel, martin alwrence, jada and keke and we loved them and the messy gossip, same with BET etc. Like for us we are quick to defend our people and keep it within our spaces if you know what I mean. Like I think about keke palmer like thats sister, like we will defend her cause she understands the culture and she was a part of black television forevwr part of our childhoods same with zendaya( though there is a problematic contingent of blackfans that question her blackness, which a by product of systemic white supremacy and racism)

Thank you Anon for explaining that.

I do think that on some degree, black actors just aren't given the same level of fame or excitement. That also has to do with the demographic of this country, and let's also not forget that some counties overseas are WAY more racist even than the US.

I will STILL not forget how China (one of the biggest box office nations) and even South Korea attacked Halle and had one of the lowest box office numbers when "The Little Mermaid" hit theaters due to Halle's race. 😤

Some countries will even straight up ERASE people of color from the posters even though they are featured on the US version just simply because they are black. 🙄

Sad to say, racism is a GLOBAL problem, not just an American one, and therefore, I don't think too many black actors will ever have the same "appeal" (esp worldwide) as their white counterparts. 🤷🏾‍♀️

I think Will Smith was really one of the very few who was on top and seemed to have a lot of crossover appeal, with people from all over the color spectrum loving him and his films. Will used to put butts in SEATS.

Now look.... 🥴 One bad decision during a LIVE Oscar show program and now he's blacklisted until goodness knows when. 😩

[twinkl22004]

“Blackfan-Diamond Anemia”, Victor McKusick, Mendelian Inheritance in Man, 1966. 黑扇-鑽石貧血。(DBA5).

Here I present: “Blackfan-Diamond Anemia”, Victor McKusick, Mendelian Inheritance in Man’, 1966. 黑扇-鑽石貧血。(DBA5). INTRODUCTION. Diamond–Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. DBA causes low red blood cell counts (anemia), without substantially affecting the other blood components (the platelets and the white blood cells), which are usually…

[thealphareporter]

Diamond Blackfan Anemia Market is Expected to Expand at a Healthy Growth Rate During the Forecast Period (2023-2032)| Key Companies Novartis Pharmaceuticals, Bellicum Pharmaceuticals

http://dlvr.it/SwdQJn

[phonemantra-blog]

Diamond Blackfan Anemia (DBA): Shedding Light on a Rare Blood Disorder Welcome to our comprehensive guide on Diamond Blackfan Anemia (DBA), a rare and perplexing blood disorder. In this article, we will delve into the intricacies of DBA, its symptoms, causes, and available treatment options. Whether you're seeking information for yourself or a loved one, understanding DBA is the first step towards managing and coping with this condition. [caption id="attachment_56194" align="aligncenter" width="750"] diamond blackfin anemia[/caption] Symptoms of DBA Identifying Diamond Blackfan Anemia: Key Symptoms and Signs One of the crucial aspects of tackling Diamond Blackfan Anemia (DBA) is recognizing its telltale symptoms. DBA primarily manifests as a severe form of anemia, which is often accompanied by a range of other distressing signs. Let's take a closer look at the key symptoms associated with DBA: Anemia: DBA results in a significant reduction in red blood cells, leading to fatigue, pallor, and overall weakness. Fatigue and Weakness: Individuals with DBA often experience extreme tiredness, making it challenging to engage in daily activities. Other Associated Symptoms: DBA can also present with various additional symptoms, including craniofacial and skeletal abnormalities, heart problems, and growth issues in children. Causes and Risk Factors Diamond Blackfan Anemia (DBA) has a strong genetic component, making it essential to understand its underlying causes and risk factors. Here, we explore the genetic basis of DBA and the factors that increase the likelihood of developing this condition. Genetic Basis: DBA is primarily caused by mutations in certain genes responsible for the production of red blood cells. Mutations in genes like RPS19, RPL5, and RPL11 disrupt this process, leading to DBA. Inherited vs. Sporadic Cases: DBA can be inherited from parents with mutated genes or occur sporadically due to de novo mutations. Understanding the mode of transmission is crucial for families affected by DBA. Risk Factors: While DBA is a genetic disorder, there are no known lifestyle-related risk factors. However, having a family history of DBA increases the risk of inheriting the condition. Diagnosis Diagnosing DBA: Unraveling the Mystery Diagnosing Diamond Blackfan Anemia (DBA) requires a careful evaluation of symptoms and specialized tests. Understanding the diagnostic process is crucial for timely intervention. Here's how DBA is diagnosed: Blood Tests: The first step in DBA diagnosis involves a series of blood tests, including a complete blood count (CBC) and reticulocyte count. These tests assess the levels of red blood cells and their precursors. Genetic Testing: Confirming DBA often involves genetic testing to identify mutations in specific genes like RPS19, RPL5, and RPL11. Genetic analysis helps to distinguish DBA from other types of anemia. Differential Diagnosis: DBA shares some symptoms with other blood disorders, such as aplastic anemia or congenital dyserythropoietic anemia. A comprehensive evaluation is essential to rule out other conditions. Treatment Options Managing DBA: Treatment Strategies and Options While there is no cure for Diamond Blackfan Anemia (DBA), several treatment options are available to alleviate symptoms and improve the quality of life for those affected. Let's explore the primary treatment approaches: Steroid Therapy: Corticosteroids like prednisone are often the first line of treatment for DBA. They stimulate red blood cell production and can lead to significant improvement in anemia. Blood Transfusions: In severe cases or when steroid therapy is ineffective, regular blood transfusions may be necessary to maintain healthy hemoglobin levels. Bone Marrow Transplant: For some individuals with DBA, a bone marrow transplant offers a potential cure. This procedure involves replacing the defective bone marrow with healthy donor marrow. Living with DBA Thriving with DBA: Coping Strategies and Support Living with Diamond Blackfan Anemia (DBA) can be challenging, but with the right strategies and support, individuals can lead fulfilling lives. Here are some essential aspects to consider: Coping Strategies: Learning to manage fatigue, pain, and the emotional impact of DBA is crucial. Maintaining a balanced lifestyle, including a nutritious diet and regular exercise, can help. Support Networks: Joining DBA support groups and connecting with others facing similar challenges can provide invaluable emotional support and practical advice. Emotional Well-being: Addressing the mental health aspects of living with a chronic illness is essential. Seeking therapy or counseling can be beneficial for individuals and their families. Ongoing Research Advancements in DBA Research: A Glimpse into the Future Diamond Blackfan Anemia (DBA) research is continuously evolving, offering hope for improved treatments and potentially even a cure. Stay informed about the latest developments: Advances in DBA Treatment: Researchers are exploring new medications and therapies aimed at addressing the underlying genetic mutations responsible for DBA. Clinical Trials: Participating in clinical trials can provide access to cutting-edge treatments. We'll keep you updated on ongoing trials and opportunities for involvement. The Role of Genetics: As our understanding of the genetic basis of DBA deepens, it opens doors to targeted therapies that may revolutionize treatment. Prevention and Genetic Counseling Navigating DBA Genetics: Prevention and Family Planning Understanding the genetic aspects of Diamond Blackfan Anemia (DBA) can be crucial for families. Explore options for prevention and family planning: Preconception and Prenatal Counseling: Learn about genetic counseling before and during pregnancy to assess the risk of passing DBA to your child. Family Planning: Make informed decisions about family size and explore options such as in vitro fertilization (IVF) with genetic testing. Frequently Asked Questions about DBA 1. Q: What is Diamond Blackfan Anemia (DBA)? Diamond Blackfan Anemia (DBA) is a rare and inherited blood disorder characterized by a severe shortage of red blood cells, leading to anemia. 2. Q: What causes DBA? DBA is primarily caused by genetic mutations in specific ribosomal protein genes, such as RPS19, RPL5, and RPL11. 3. Q: Is DBA a hereditary condition? Yes, DBA can be inherited from parents who carry the mutated gene, although sporadic cases can also occur due to de novo mutations. 4. Q: What are the common symptoms of DBA? Key symptoms include anemia, fatigue, weakness, and, in some cases, craniofacial abnormalities, heart issues, and growth problems. 5. Q: How is DBA diagnosed? DBA is diagnosed through blood tests, genetic testing to identify specific mutations, and a differential diagnosis to rule out other anemia-related conditions. 6. Q: What are the treatment options for DBA? Treatment may involve steroid therapy, blood transfusions, and, in some cases, bone marrow transplantation for a potential cure. 7. Q: Can DBA be cured? While there is no known cure, some cases of DBA can be successfully treated, and ongoing research offers hope for future treatments. 8. Q: How can I support a loved one with DBA? Offer emotional support, assist with treatment routines, and encourage them to connect with DBA support networks for guidance. 9. Q: Are there lifestyle changes that can help manage DBA symptoms? Maintaining a balanced diet, regular exercise, and managing stress can improve the overall well-being of individuals with DBA. 10. Q: Can DBA be prevented through genetic counseling? Preconception and prenatal genetic counseling can help assess the risk of passing DBA to future generations, aiding in family planning decisions. Conclusion: In conclusion, Diamond Blackfan Anemia (DBA) is a rare blood disorder with unique challenges, but it's a condition that can be managed with the right knowledge and support. By recognizing the symptoms, seeking early diagnosis, exploring treatment options, and staying informed about research advancements, individuals and families affected by DBA can lead fulfilling lives. Remember that you're not alone on this journey. Joining support networks, seeking emotional well-being, and staying engaged in the latest research can make a significant difference. Stay hopeful, stay informed, and keep advocating for a brighter future for DBA.

[lamilanomagazine]

Verona: Le Soffitte in Piazza, sabato appuntamento al Parco San Giacomo

Verona: Le Soffitte in Piazza, sabato appuntamento al Parco San Giacomo. Abiti vintage, vecchi utensili, libri, riviste e fumetti. Ma anche dischi, giocattoli e attrezzi sportivi, tutti rispolverati da armadi, cantine e garage. E' in programma sabato 23 settembre al parco San Giacomo in 5^ Circoscrizione l'iniziativa 'Soffitte in piazza', i mercatini dell'usato nei quartieri organizzati dal Comune con il supporto delle associazioni DBA-Anemia Diamond Blackfan Italia ODV e Storie Creative. Anche quest'anno privati e associazioni senza scopo di lucro, potranno dare nuova vita ai propri oggetti attraverso scambi, baratti o vendite. L'iniziativa infatti ha come obiettivo quello di sensibilizzare al riuso evitando lo spreco in un periodo storico nel quale è sempre più fondamentale avere una coscienza ecologica e sostenibile. Chiunque può partecipare come espositore, l'iscrizione è obbligatoria e gratuita collegandosi, a questo link. Per informazioni www.comune.verona.it cercando poi 'Soffitte in piazza'. L'iniziativa è stata presentata questa mattina dal presidente della 5^ Circoscrizione Raimondo Dilara. "Uno spazio e una vetrina nel quartiere in cui gli espositori potranno vendere o barattare usati di modesto valore" ha evidenziato il presidente Dilara. Il prossimo e ultimo appuntamento con Soffitte in Piazza 2023 sarà il 7 ottobre in Circoscrizione 7^ in piazza Frugose alla Parrocchia Beato Carlo Steeb a San Michele Extra.... #notizie #news #breakingnews #cronaca #politica #eventi #sport #moda Read the full article

[sakurailady]

New fan 😄 #fan #blackfan #butterflies🦋 #purple #purplebutterfly #collection #random #randomphoto #randomshit https://www.instagram.com/p/CckxI07DIHM/?igshid=NGJjMDIxMWI=