#a lot of people he ends up dealing with speak at least passable Latin so at a pinch they might perhaps try switching to that?

[canisalbus]

I just recently started following you so i don't have the full lore of your murderous gay religiously traumatized doggos, BUT, from my understanding, they are Italian and i don't know what part of Italy they are from, yet i can't help headcanoning Vasco as Tuscan, while Machete is probably from some part of Veneto. And as an Italian who has heard Tuscans and Veneto dialet, well it's an hilarious mental image.

Vasco is indeed Tuscan, Florentine to be specific. He comes from a wealthy and influential noble family that has lived in Florence for centuries. He's proud of his roots, and it's usually easy for strangers to tell where he's from. He's a resonably successful politician and has worked as an ambassador and representative of Florence on numerous occasions.

Machete is originally Sicilian (ironically about as far from Veneto as possible), although he was taken to mainland at young age and has lived in several places since then, before ending up in Rome. The way I see it, he exhibits very little local color, his demeanor and (even though Italian hadn't become a standardized language yet) way of speaking are formal, neutral and scarcely give away any hints about his personal history, at least in the 16th century canon.