#RT PCR test for COVID-19

[247labsnpr]

We provide covid-19 testing services. 24-7 Labs is the first of a new line of innovative healthcare services providers. Our mission is to give people the power to control their health by providing convenient, affordable, and easy-to-understand options.

[conceptodiagnostics]

3 Benefits of Corporate Covid-19 Testing

Coronavirus is a respiratory disease brought about by SARS-CoV-2. Most patients contaminated with Covid report gentle to direct side effects and recuperate with the Private Pathology Laboratory in the UK. Nonetheless, patients with previous medical conditions like hypertension, disease, and diabetes might encounter unfavorable impacts. In any case, note that anybody can get the infection, become sick or even kick the bucket, no matter what their age.

 When can you use Corporate Covid-19 testing?

You ought to get tired or Book a Covid-19 Travel Test from the Clinic of the UK, assuming you experience any side effects of Coronavirus, regardless of whether you have gotten every one of the essential antibodies.

Note that Covid spreads rapidly and effectively, even before seeing any side effects. Thusly, the sooner you know whether you have the infection, the better since you can detach it and lessen the possibility of spreading it to other people.

Once in a while you might test negative for the infection yet feel unwell, demonstrating a bogus negative. In such a situation, you ought to disengage and contact your primary care physician to examine your side effects. Nonetheless, assuming you test positive, you should promptly detach and contact your Private Blood Tests Clinic in the UK to begin the treatment plan.

According to Diagnostic Centre in UK, you ought to do a test following five to seven days on the off chance that you are immunized against the infection. Furthermore, if you're not immunized, you ought to get a test. Given below are the 3 Benefits of Corporate Covid-19 testing:

1.    Ensures Successful Detachment

There are various difficulties confronting the battle against the spread of Covid. Luckily, medical services suppliers can utilize fast testing from the Corporate Coronavirus Testing of the UK to analyze whatever number of Coronavirus cases would be prudent before the infection spreads to the more extensive populace.

2.    Simple to Utilize

You don't need to be a clinical expert to do a quick Coronavirus test. You can do it with your family utilizing a home Coronavirus test pack.

3.    Mitigates Financial Effect

With fast testing, people presented with the infection accept their test results within a couple of hours, implying that they don't need to disengage for a long time or miss various business days as they hold back to accept their experimental outcomes. For more information visit the Private Pathology Laboratory in the UK.

 It can be concluded that Patients go through analytic tests from the Diagnostic Centre in the UK to affirm the presence of Coronavirus respiratory sickness. At the point when patients test positive for a fast antigen test, they are disengaged and begin treatment right away.

 Also Read: What Is So Fascinating About the Covid-19 Antigen LFT Test?

[covid-safer-hotties]

Also preserved on our archive

Whenever you hear someone trying to blame kid's poor test scores "post pandemic" on "lockdowns," show them this.

By Dr. Sushama R. Chaphalkar, PhD.

New research shows that mild COVID-19 alters brain structure and connectivity in key areas responsible for memory and cognition, emphasizing the lasting effects on young people’s brain health.

In a case-control study published in the journal Translational Psychiatry, researchers used magnetic resonance imaging (MRI) and cognitive tests to examine brain structure, function, and cognition in adolescents and young adults with mild coronavirus disease 2019 (COVID-19) compared to healthy controls in a pandemic hotspot in Italy. They identified significant changes in brain regions related to olfaction and cognition, with decreased brain volume and reduced functional connectivity in areas like the left hippocampus and amygdala, which were linked to impaired spatial working memory. Notably, no significant differences were observed in whole-brain connectivity, suggesting that these changes were localized rather than widespread.

Background COVID-19, primarily known for respiratory symptoms, also affects the central nervous system, leading to neurological issues like headaches, anosmia, and cognitive changes. MRI-based studies reveal anatomical brain changes in COVID-19 patients, such as reduced gray matter and decreased volume in regions like the hippocampus and amygdala, often linked to cognitive deficits.

While research mostly focuses on severe cases and older adults, a majority of infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, occur in adolescents and young adults who also experience long-lasting cognitive symptoms.

This age group, undergoing key brain development, is impacted by changes in spatial working memory and brain structure, which are crucial for cognitive functions shaped by social interactions, significantly disrupted by the pandemic.

Given that this is the largest and most understudied population affected by COVID-19, understanding the brain and cognitive impacts in adolescents and young adults is vital.

Therefore, researchers in the present study compared anatomical, functional, and cognitive outcomes, utilizing a longitudinal design that allowed them to assess both pre- and post-infection differences, in COVID-19-positive and negative adolescents and young adults from Lombardy, Italy, a global hotspot during the pandemic.

About the study The present study involved participants from the Public Health Impact of Metal Exposure (PHIME) cohort, a longitudinal investigation of adolescents and young adults in northern Italy. Between 2016 and 2021, 207 participants, aged 13 to 25 years, were included in a sub-study with MRI scans and cognitive tests. After COVID-19 restrictions were lifted, 40 participants (13 COVID+ and 27 COVID−) participated in a follow-up study, which replicated the MRI and cognitive assessments.

The mean age of participants was 20.44 years and 65% were female. COVID+ status was confirmed through positive reverse transcription polymerase chain reaction (RT-PCR) tests within 12 months of follow-up. Neuropsychological assessments used the Cambridge Neuropsychological Test Automated Battery (CANTAB) to evaluate spatial working memory.

MRI and functional MRI data were acquired using a 3-Tesla scanner, processed, and analyzed for structural and local functional connectivity using eigenvector centrality mapping (ECM) and functional connectivity (FC) metrics. Whole-brain functional connectivity metrics showed no significant differences between COVID+ and control groups, indicating that the observed changes were specific to key brain regions rather than generalized across the entire brain.

Statistical analysis involved the use of pairwise Student's t-tests, Kolmogorov–Smirnov test, linear regression, two-waves mediation analysis, negative binomial regression, and linear regression, all adjusted for covariates.

Results and discussion Significant differences were observed in the two groups regarding the time between assessments, COVID-19 symptoms, and vaccine status. The research identified five localized functional connectivity hubs with significant differences between the two groups, including the right intracalcarine cortex, right lingual gyrus, left frontal orbital cortex, left hippocampus and left amygdala, which is vital for cognitive functions. Only the left hippocampal volume showed a significant reduction in COVID+ participants (p = 0.034), while whole-brain connectivity remained unchanged, reinforcing the localized nature of the brain changes.

The left amygdala mediated the relationship between COVID-19 and spatial working memory "between errors" (p = 0.028), a critical finding that highlights the indirect effect of amygdala connectivity on cognitive function in COVID+ individuals. This mediation analysis underscores the role of specific brain regions in influencing cognitive deficits, as only the indirect effect was statistically significant for spatial working memory errors. The orbitofrontal cortex, involved in sensory integration and cognitive functions, also showed decreased connectivity in COVID+ individuals, supporting previous findings of structural and functional changes in this region during COVID-19.

The study is limited by small sample size, lack of diversity, potential confounding factors due to the long interval between MRI scans, treatment of certain subjects as COVID-negative based on antibody testing beyond the 12-month threshold, and the possibility of non-significant findings in mediation analysis due to these factors.

Conclusion In conclusion, the findings indicate persistent structural and functional alterations in specific brain regions of COVID-19-positive adolescents and young adults, including changes in gray matter volume and localized functional connectivity, which correlate with diminished cognitive function, particularly in working memory.

Further research is necessary to evaluate the longevity and potential reversibility of these brain and cognitive changes post-infection, enhancing our understanding of post-COVID outcomes and informing future interventions and treatments. The longitudinal design of this study, with pre- and post-COVID data, strengthens these findings by allowing direct comparisons over time, offering robust insights into the impact of COVID-19 on adolescent brain development.

Journal reference: COVID-19 related cognitive, structural and functional brain changes among Italian adolescents and young adults: a multimodal longitudinal case-control study. Invernizzi, A. et al., Translational Psychiatry, 14, 402 (2024), DOI: 10.1038/s41398-024-03108-2, www.nature.com/articles/s41398-024-03108-2

[darkmaga-returns]

The C19 disease caused by the airborne SARSCOV2 virus is reported to have killed 7 million people from 700 million “cases” over its five years of existence.

Coronavirus Graphs: Worldwide Cases and Deaths - Worldometer

We now know that the number of “cases” is a fiction, borne of a bogus RT-PCR test – probably more than 90% of case diagnoses were false.

Countries like Australia, New Zealand, Germany and Japan managed to avoid the first year of the scamdemic, 2020, by restricting all social interactions – denying life to their citizens. Germany and Japan chose not to use end of life treatments to euthanize those identified as “cases“ with “treatments” like Remdesivir, Midazolam, morphine and fentanyl – and the ventilators/respirators that prevented the “infected” from breathing on medics.

The number of C19 “cases” and deaths with C19 present exploded from 85 million at end of 2020 with around 2 million deaths reported in 2020 - with C19 present using the bogus RT-PCR test.

Note the WHO issued instructions – based on the bogus RT-PCR test – to treat all deaths with a positive test as a C19 death.

Our World in Data reports that 80% of the world’s 8 billion people received 13.7 billion injections.

[mariebenz]

Trained Scent Dogs Can Quickly and Accurately Detect Covid-19

MedicalResearch.com Interview with: Prof. Tommy Dickey Ph.D. Distinguished Professor Emeritus Geography Department University of California Santa Barbara Santa Barbara, CA

MedicalResearch.com: What is the background for this study? Response:  I became interested in dog's sense of smell several years ago while doing therapy dog demonstrations at the California Science Center in Los Angeles during a special traveling exhibit "Dogs! A Science Tail." (Now at the Orlando Science Center).  I did a lot of research on this topic and taught children about it through the Los Angeles Public Library using my Great Pyrenees therapy dogs. Then, COVID broke out and I expanded my research into any work being done to possibly utilize scent dogs for screening and testing for COVID.  I found only a few such studies.  However, I fortuitously met Heather Junqueira of BioScent, Inc. (in Florida) online and she was beginning to successfully teach her beagles to detect COVID-related odors.  She agreed to co-author a peer-reviewed review paper with me.  That led to our first paper - Dickey, T, Junqueira, H. Toward the use of medical scent dogs for COVID-19 screening. J Osteopath Med 2021;1(2): 141-148. https://doi.org/10.1515/jom-2020-0222 When the COVID pandemic began to wane at the beginning of this year, I felt that it would be the perfect time to do this comprehensive follow-up review to see how far COVID scent dog research had progressed. To our amazement, research efforts had increased by almost tenfold and involved over 400 scientists using over 31,000 samples (including sniffings) from over 30 countries and that 29 peer reviewed papers had been published. Heather’s inspiration for doing scent dog work came when her father contracted cancer and she wanted to find better diagnostics.  She has since been successful in detecting non-small cell lung cancer with her trained beagles as well as COVID. MedicalResearch.com: Would you tell us a little about the type and/or breeding of the dogs? Response:  In the peer-reviewed studies, the number of different breeds and mixed breeds was 19.   Typical training periods dedicated to COVID scent detection were a few weeks. Labrador Retrievers and Belgian Malinois were most commonly used (nearly 100 times). These breeds were chosen because they have been used extensively in scent detection work for several purposes.  Other breeds, such as Heather’s beagles, have been used quite successfully as well. No obvious preference based on performance has been noted by breed, age, gender, age or even previous training for scent work. Interestingly, most of the dogs were not specifically bred to do COVID detection.  In fact, previously untrained dogs have the advantage that they are not as prone to indicating on scents other than the COVID-19 associated scent. Heather is one of the few scientists who actually breeds her dogs to be single purpose scent dogs (i.e., for COVID or other diseases). MedicalResearch.com: What are the main findings? 1)    Our review has shown that it safe to utilize scent dogs to directly screen and test individuals who may be infected with the COVID-19. 2)    The accuracy of the trained scent dog method is comparable to or in some cases superior to the real-time reverse transcription polymerase chain reaction (RT-PCR) test and the antigen (RAG) test. 3)    Trained scent dogs can be effectively used to provide quick (seconds to minutes), non-intrusive, and accurate results in public settings and thus reduce the spread of COVID. MedicalResearch.com: What should readers take away from your report? - Medical scent dogs deserve their place as a serious diagnostic methodology that could be particularly useful during pandemics, potentially as part of rapid health screenings in public spaces. We are confident that scent dogs will be useful in detecting a wide variety of diseases in the future. - We feel that the impressive international COVID scent dog research described in our paper, perhaps for the first time, demonstrates that medical scent dogs are ready for mainstream medical applications.  MedicalResearch.com: What recommendations do you have for future research as a results of this study? 1)    More studies utilizing more dogs would be beneficial 2)    More work in developing target samples is needed 3)    More research is needed in different public settings. MedicalResearch.com: Is there anything else you would like to add? Any disclosures? - More trained dogs will be needed for wide-spread, large-scale scent dog screening and testing.   The training and field use of scent dogs may benefit from the recruitment of dog owners who are already involved in recreational scent work under the auspices of the American Kennel Club and other organizations worldwide. - Is the use of scent dogs cost effective?  Much of the research in this review was in fact motivated by the need for rapid, inexpensive, and lower technological testing in developing nations.  More research into the economics is needed. - Perhaps the greatest challenge to the use of medical scent dogs is the implementation of wide-spread, large-scale programs, which will require funding and development of infrastructure that is responsible for certification, protocol standards, and deployments. This may be more of a challenge in the U.S. for a variety of bureaucratic reasons. Other nations face a variety of obstacles, but the large number of scent dogs already used in practical applications (seen in our paper’s References and Tables) suggests that their governments are quite supportive of the common use of medical scent dogs and may not place as many governmental barriers. Citation: Dickey, Tommy and Junqueira, Heather. "COVID-19 scent dog research highlights and synthesis during the pandemic of December 2019−April 2023" Journal of Osteopathic Medicine, 2023. https://doi.org/10.1515/jom-2023-0104 The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.     Read the full article

[killed-by-choice]

Ashwini Thavai, 36 (India 2021)

In India in 2021, 36-year-old Ashwini Thavai was pregnant in a global pandemic. When she was 6 weeks pregnant, she was pressured to have a legal abortion for unspecified “health reasons”. Far from being good for her health, abortion would soon kill her.

Ashwini was given the abortion pill, but it resulted in an incomplete abortion, a common complication of the pill. On May 1 she was brought to the hospital for a surgical procedure to remove the corpse of her baby, but she bled heavily and died just 45 minutes after being transferred to another hospital.

From there, a cover-up began to try to hide the real cause of death. 6 doctors (2 of them from the pathology lab) tried to blame Ashwini’s death on COVID-19 and refused to hand over her body for further examination. Their fraud was exposed when from an antigen test and RT-PCR tests performed the day before her death all stated that she was Covid-negative.

All 6 of the doctors involved in the death and cover-up were booked by police. (Important note: Abortion is legal in India, but killing a woman with an abortion is not.)

Abortion-related maternal deaths are not as rare as abortionists want people to think. This is not the first time someone attempted to blame a legal abortion death on another cause. There may be many more cases similar to Ashwini that haven’t been discovered yet.

https://www.msn.com/en-in/news/other/doctors-botch-abortion-try-to-show-fatality-as-covid-death-booked/ar-AAPFNFH

[indiabookmytest]

We provides various offers and discounts on COVID-19 testing services in India. Users can select their preferred city and view the available offers on COVID-19 tests such as RT-PCR tests, rapid antigen tests, and more. The website also provides information on the different types of tests available, their respective costs, and the locations of the testing centers. Overall, the website aims to help people get access to COVID-19 testing services at an affordable price

[agdiagnostics]

RT PCR Test Preparation: Expert Tips for Accurate Results

Introduction to RT PCR Test Preparation

The RT PCR test plays a critical role in detecting viral infections like COVID-19. It is known for its accuracy, making it a valuable tool in managing and preventing the spread of viruses. If you're preparing for an RT PCR Test in Pune, following proper guidelines can help ensure that your results are as accurate as possible. The better the preparation, the more reliable the outcome.

Choosing the Right Diagnostic Centre

Before preparing for your RT PCR Test, selecting the right diagnostic centre is crucial. Ensure the facility is certified and follows all necessary health protocols. Look for centres that provide clear instructions on how to prepare for the test and offer reliable services. A trusted centre, like AG Diagnostics, ensures a smooth experience, from booking your test to receiving your results.

Timing Your Test for Maximum Accuracy

The timing of your RT PCR test is important for ensuring accurate results. If you're experiencing symptoms, it is best to wait for at least 3 to 5 days after exposure or the onset of symptoms before getting tested. This gives the virus enough time to replicate, making it detectable in the sample. If you are asymptomatic but have had close contact with a confirmed case, follow the guidelines provided by the healthcare professionals.

Avoiding Certain Foods and Drinks Before the Test

To ensure accurate results, it is advisable to avoid consuming food or drinks before the test. Refrain from eating or drinking for at least an hour prior to your RT PCR test. This helps in obtaining a clearer sample and reduces the chances of contamination, which can interfere with the test. Staying hydrated is essential, but try to avoid beverages that may irritate your throat or mouth.

Avoiding Smoking and Alcohol

It is important to avoid smoking and alcohol consumption 24 hours before your RT PCR Test in Pune. Both smoking and alcohol can affect the test sample, especially by altering your saliva or mucous membranes, which are used in the test. By refraining from these habits, you can help ensure that the sample collected is as pure as possible.

Understanding the Testing Process

Knowing what to expect during your RT PCR test can help reduce anxiety and ensure a smoother experience. The sample is usually collected through a nasal or throat swab. It is a quick procedure but may cause temporary discomfort. Keeping calm and relaxed during the test can help the process go smoothly.

Proper Hygiene Practices Before the Test

Practicing good hygiene before the test is essential. Wash your hands thoroughly before the test, and if possible, wear a mask. This reduces the risk of contamination and ensures a clean environment for the test sample. If you need to cough or sneeze, make sure to do so into a tissue or your elbow, and dispose of it properly before proceeding.

Following the Instructions of Healthcare Professionals

Each diagnostic centre may have specific instructions based on their protocols. Ensure you follow these instructions carefully. Some centres may request that you refrain from using nasal sprays, inhalers, or other medications prior to the test. These steps help ensure that the results are as accurate as possible, as certain substances can interfere with the test sample.

Ensuring Proper Sample Collection

Accurate RT PCR test results depend on the quality of the sample collected. Make sure the healthcare professional collects the sample in a manner that adheres to established guidelines. It is important that the sample is taken from the correct location (throat or nasal passage) to minimize errors. If the procedure is not done correctly, you may need to repeat the test.

Resting Before Your Test

Before your RT PCR test, try to rest well the night before. Being well-rested helps you stay calm and composed during the test. It can also improve your overall health and reduce stress, which may affect your body's response to the test. Avoid overexerting yourself, and ensure you are physically prepared for the procedure.

What to Do If You’re Feeling Unwell

If you're feeling unwell on the day of the test, be sure to inform the healthcare professionals beforehand. Symptoms like fever, cough, or shortness of breath could indicate that you might need additional tests or medical attention. Clear communication ensures that the RT PCR test is conducted in a safe and appropriate manner, both for you and for others.

Keeping Track of Your Health Status

Track any symptoms or changes in your health before your test. If you've been in close contact with someone who tested positive for COVID-19, it is important to note this. Accurate self-reporting will help the healthcare team make informed decisions about the best approach for testing and treatment. Monitoring your health closely can lead to better care and more effective testing outcomes.

Avoiding Stress and Anxiety

The thought of undergoing a test can be stressful, especially when the results are crucial. However, it's important to stay calm and relaxed during the process. Stress and anxiety can negatively impact your health and your immune system, so try to practice deep breathing or meditation techniques before and during the test. A calm mind contributes to a smoother experience.

Understanding Test Results

Once the test is complete, you will typically receive your results within 24 to 48 hours. It is important to note that while RT PCR tests are highly accurate, there is always a small chance of false negatives or positives. If you have any concerns about your results, consult with a healthcare professional for further guidance and possible retesting.

Post-Test Care and Follow-Up

After your RT PCR Test, make sure to follow the post-test instructions provided by the diagnostic centre. In the case of a positive result, isolate yourself and inform anyone you’ve been in contact with. If your test is negative but you're still showing symptoms, you may need additional testing or care.

Conclusion

Preparing for an RT PCR test is crucial to obtaining accurate and reliable results. From selecting the right diagnostic centre to understanding the procedures and following hygiene protocols, every step counts. For patients in Pune, AG Diagnostics offers expert care, ensuring a smooth and reliable RT PCR testing experience. They provide high-quality diagnostic services, following the best practices for patient care and testing accuracy.

[kristinahertzz]

Hantavirus Diagnostics Market

Hantavirus Diagnostics Market Size, Share, Trends: Roche Diagnostics Lead

Advancements in Molecular Diagnostics Driving Market Growth Worldwide

Market Overview

The Hantavirus Diagnostics Market is experiencing steady growth, with a projected CAGR of 5.8% from 2024 to 2031. North America currently leads the market, driven by a higher incidence of hantavirus cases, advanced healthcare infrastructure, and increased awareness about the disease. Key metrics include rising investments in infectious disease diagnostics, growing demand for rapid and accurate testing methods, and increasing government initiatives for disease surveillance and control.

The market is expanding due to the rising prevalence of hantavirus infections worldwide, particularly in rural and suburban areas. The COVID-19 pandemic has also increased awareness of zoonotic infections, resulting in a renewed emphasis on improving diagnostic skills for viruses such as hantavirus.

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Market Trends

Significant advances in molecular diagnostic techniques are transforming the field of hantavirus diagnostics, especially RT-PCR (Reverse Transcription Polymerase Chain Reaction) technology. These advancements enhance the sensitivity and specificity of hantavirus detection, enabling more timely and accurate diagnoses. Recently, multiplex PCR techniques capable of detecting multiple hantavirus strains simultaneously have been developed, reducing diagnostic time and costs.

There is also a growing interest in developing portable and point-of-care molecular diagnostic tools for hantavirus detection. These devices provide rapid and accurate testing capabilities in remote or resource-limited settings where hantavirus infections are more prevalent. For instance, a novel isothermal amplification method for hantavirus detection, performed on a portable device, can produce results in less than an hour.

Market Segmentation

The RT-PCR (Reverse Transcription Polymerase Chain Reaction) segment is expected to dominate the Hantavirus Diagnostics market during the forecast period. This segment's growth is largely due to the high sensitivity and specificity of RT-PCR testing in detecting hantavirus RNA, facilitating early and accurate diagnoses.

Recent advancements in the RT-PCR sector have focused on improving testing speed and efficiency. For example, several diagnostic companies have developed automated RT-PCR systems capable of handling multiple samples simultaneously, significantly reducing turnaround time. These advancements are particularly beneficial during outbreaks, where rapid testing of a large number of samples is crucial.

The COVID-19 pandemic has indirectly benefited the RT-PCR segment. The widespread use of RT-PCR testing for SARS-CoV-2 has led to increased investment in PCR infrastructure and expertise, which can be leveraged for hantavirus testing. The Association of Public Health Laboratories estimated a 25% increase in molecular testing capacity across public health labs in 2020, enhancing the availability of RT-PCR testing for other infectious diseases, including hantavirus.

Market Key Players

Prominent players in the Hantavirus Diagnostics Market include:

Roche Diagnostics

Abbott Laboratories

Thermo Fisher Scientific

bioMérieux SA

Qiagen N.V.

Siemens Healthineers

DiaSorin S.p.A.

Hologic, Inc.

Becton, Dickinson and Company

Bio-Rad Laboratories, Inc.

These leading companies are investing in technological advancements, strategic collaborations, and expanding their product portfolios to maintain their competitive edge.

Contact Us:

Name: Hari Krishna

Email us: hari.krishna@aurorawaveintellects.com

Website: https://aurorawaveintellects.com/

[global-research-report]

Comprehensive Study on the Multiplex Assay Market

The global multiplex assay market size is expected to reach USD 3.87 billion by 2030, registering a CAGR of 14.77% from 2023 to 2030, according to a new report by Grand View Research, Inc. The growing prevalence of infectious diseases is boosting the usage of multiplex assays in clinical trials. For instance, according to the American Cancer Society in 2021, 1.9 million cancer cases were reported along with 6,08,570 deaths in the United States. Multiplex assay aids in the diagnosis of cancer and reduces unnecessary invasive producers. Thus, growing chronic diseases can boost the necessity of these assays and is anticipated to fuel market growth. The increasing adoption of personalized medicine in recent years is another key factor driving the growth.

Personalized medicine is a precise medicine for an individual patient to attain improved treatment options based on the body type and disease risk. These assays ensure to be highly beneficial for the comprehensive diagnosis of personalized medicines. For instance, according to an article published in the MDPI journal in 2020, multiplex immunoassay provides a complete picture of the disease and pathways involved in Rheumatoid Arthritis (RA) and simultaneously analyzes multiple proteins that can yield biomarker signatures of RA subtypes to enable patients to benefit from personalized medicine. During the COVID-19 pandemic, multiplex testing continued to be an essential tool for healthcare professionals in effectively managing the spread of COVID-19. In addition, recently, several private companies have also developed novel versions of multiplex assays.

For instance, in Sept 2020, LabCorp launched an at-home collection version for diagnosis of influenza A/B, COVID-19, and respiratory syncytial virus single-panel tests. Furthermore, the advantages of multiplex assay over singleplex and traditional assay can boost the industry growth in coming years. Several benefits offered by these automated tests include microsampling capability, numerous arrays measured in a single trial, quicker results, high operational efficiency, easy operations, and reduced labor expenses. Thus, the industry has witnessed incremental growth in 2021 and is anticipated to have a similar trend during the forecast period. Moreover, increasing validation of the biomarkers in molecular & protein diagnostics and the rising need for high-throughput and automated systems are expected to create lucrative opportunities during the forecast period.

Multiple biomarker analysis has a wide range of applications in the area of infectious diseases, neurodegenerative diseases, autoimmune diseases, and cancer. Numerous biomarkers are being discovered, and there is a high possibility of the development of novel diagnostics. For instance, Cipla launched RT Direct multiplex PCR kit that delivers quicker results for COVID-19. Such developments can increase the market penetration of multiplex assay during the forecast period. The technological advancements and automation in the multiplex assay, improve the efficiency and speed of delivering accurate results. For instance, in July 2020, Luminex provided xMAP the INTELLIFLEX system to discover novel applications, including the exclusive ability to detect multiple antibodies in a single serology test.

In May 2022, Vela Diagnostics launched a highly automated multiplex PCR-based test for detecting antimicrobial resistance genes and UTI pathogens. Hence novel technological developments can fuel the industry growth in the near future. However, the high cost of equipment can restrict the usage of multiplex assays by researchers and manufacturers in mid and low-income countries. Also, the quality control standards and regulations are more stringent for multiplex assay compared to singlex assay, which can impede the industry growth during the forecast period.

Multiplex Assay Market Report Highlights

By product, the consumables segment held the dominant share in 2022. This is due to the recurring purchase of consumables along with the rise in the number of diagnostic tests

The protein multiplex assay type segment dominated the industry in 2022 due to the increasing focus on proteomics studies for biomarker research and clinical diagnostics

The flow cytometry technology segment held a larger share in 2022. Constant efforts by various companies to launch novel and technological advanced flow cytometer is the key factor driving the segment

The research & development application segment held the largest share in 2022 due to the utilization of these assays in clinical & preclinical stages to evaluate toxicity, immunotherapy success, and drug response biomarkers

The pharmaceutical & biotechnology companies end-user segment led the industry in 2022 due to a rise in pharma & biotech partnerships and collaborations to increase the multiplexing capabilities

North America dominated the global industry in 2022 due to the growing R&D activities as a result of the increasing prevalence of chronic diseases

Asia Pacific is estimated to register the fastest CAGRfrom 2022 to 2030 due to the rising number of hospitals in emerging countries, the developing R&D sector, and the high demand for healthcare infrastructure in the region

Multiplex Assay Market Segmentation

Grand View Research has segmented the global multiplex assay market based on product, type, technology, application, end-user, and region:

Multiplex Assay Product Outlook (Revenue, USD Million, 2018 - 2030)

Consumables

Instruments

Software

Multiplex Assay Type Outlook (Revenue, USD Million, 2018 - 2030)

Protein Multiplex Assays

Planar Protein Assays

Bead-based Protein Assays

Nucleic Acid Multiplex Assays

Planar Protein Assays

Bead-based Protein Assays

Cell-based Multiplex Assays

Multiplex Assay Technology Outlook (Revenue, USD Million, 2018 - 2030)

Flow Cytometry

Fluorescence Detection

Luminescence

Multiplex Real-time PCR

Other Technologies

Multiplex Assay Application Outlook (Revenue, USD Million, 2018 - 2030)

Research & Development

Drug Discovery & Development

Biomarker Discovery & Validation

Clinical Diagnostics

Infectious Diseases

Cancer

Cardiovascular Diseases

Autoimmune Diseases

Nervous System Disorders

Metabolism & Endocrinology Disorders

Other Diseases

Multiplex Assay End-user Outlook (Revenue, USD Million, 2018 - 2030)

Pharmaceutical & Biotechnology Companies

Hospitals & Diagnostic laboratories

Research & Academic Institutes

Other End-users

Multiplex Assay Regional Outlook (Revenue, USD Million, 2018 - 2030)

North America

US

Canada

Europe

UK

Germany

France

Italy

Spain

Asia Pacific

Japan

China

India

South Korea

Australia

Latin America

Brazil

Mexico

Argentina

Middle East & Africa

South Africa

Saudi Arabia

UAE

Order a free sample PDF of the Multiplex Assay Market Intelligence Study, published by Grand View Research.

[diagnostic-283]

COVID Test in Sector 62 Noida – Accurate & Quick Testing Services

Looking for reliable covid test in sector 62 noida? Our diagnostic center provides comprehensive COVID-19 testing, including RT-PCR and rapid antigen tests, ensuring accurate and timely results. With a focus on safety and efficiency, we adhere to all health guidelines to deliver a seamless testing experience.

for more information :- https://g.co/kgs/XkHzbKq

[getwellpathlabs]

Pathology Lab in Greater Noida

[covid-safer-hotties]

Long COVID is not the same for everyone: a hierarchical cluster analysis of Long COVID symptoms 9 and 12 months after SARS-CoV-2 test - Published Sept 19, 2024

Abstract Background Identifying symptom clusters in Long COVID is necessary for developing effective therapies for this diverse condition and improving the quality of life of those affected by this heterogeneous condition. In this study, we aimed to identify and compare symptom clusters at 9 and 12 months after a SARS-CoV-2 positive test and describe each cluster regarding factors at infection.

Methods This is a cross-sectional study with individuals randomly selected from the Portuguese National System of Epidemiological Surveillance (SINAVE) database. Individuals who had a positive RT-PCR SARS-CoV-2 test in August 2022 were contacted to participate in a telephonic interview approximately 9 and 12 months after the test. A hierarchical clustering analysis was performed, using Euclidean distance and Ward’s linkage. Clustering was performed in the 35 symptoms reported 9 and 12 months after the SARS-CoV-2 positive test and characterised considering age, sex, pre-existing health conditions and symptoms at time of SARS-CoV-2 infection.

Results 552 individuals were included at 9 months and 458 at 12 months. The median age was 52 years (IQR: 40–64 years) and 59% were female. Hypertension and high cholesterol were the most frequently reported pre-existing health conditions. Memory loss, fatigue or weakness and joint pain were the most frequent symptoms reported 9 and 12 months after the positive test. Four clusters were identified at both times: no or minor symptoms; multi-symptoms; joint pain; and neurocognitive-related symptoms. Clusters remained similar in both times, but, within the neurocognitive cluster, memory loss and concentration issues increased in frequency at 12 months. Multi-symptoms cluster had older people, more females and more pre-existing health conditions at 9 months. However, at 12 months, older people and those with more pre-existing health conditions were in joint pain cluster.

Conclusions Our results suggest that Long COVID is not the same for everyone. In our study, clusters remained similar at 9 and 12 months, except for a slight variation in the frequency of symptoms that composed each cluster. Understanding Long COVID clusters might help identify treatments for this condition. However, further validation of the observed clusters and analysis of its risk factors is needed.

[darkmaga-returns]

A Scientific Explanation of the Fraud of RT-PCR Testing for COVID-19

Corinne Michels

Nov 05, 2024

“The COVID-19 PCR tests were a fraud.” You have heard this before, but is it true or just more hype? Read this report and decide for yourself. It explains the fundamentals of the RT-PCR (Reverse Transcriptase - Polymerase Chain Reaction) test kits for those who want to understand the facts. Do not expect an easy read. For starters, you will need to familiarize yourself with the basic structure of DNA. Understanding how misinterpretation of the RT-PCR test results was used to create the COVID-19 pandemic will be your reward. You will be immunized against future efforts to create fear and societal discord. Rest assured; they will try again!

A serious flu-like respiratory disease began to spread in early Fall 2019 with Wuhan, China, as “ground zero.” By December, worldwide spread of the disease was underway. Images of hapless pedestrians suddenly falling dead in the streets; overwhelmed hospitals in Lombardy, Italy; government-imposed lockdowns; and nonstop coverage of worldwide COVID deaths fanned the flames of fear surrounding this unknown disease. It was not enough to be symptom-free. People demanded the development of a test to detect silent carriers of the infectious agent.

Only the genome sequence of SARS-CoV-2 was known at the time, and the only available testing method used polymerase chain reaction, a.k.a. PCR. Despite many known contraindications, RT-PCR widespread testing for COVID-19 began. According to Dr. Trish M. Perl, an epidemiologist at Johns Hopkins and past president of the Society of Health Care Epidemiologists of America, blind faith in the results of technically complex molecular tests results in “pseudo-epidemics.”  [https://www.nytimes.com/2007/01/22/health/22whoop.html] The COVID-19 pandemic was one of those.

[neha24blog]

COVID-19 Detection Kits Market Expected To Witness A Substantial Growth Of USD 4.06 Billion By 2030: Grand View Research Inc.

San Francisco, 6 Sep 2024: The Report COVID-19 Detection Kits Market Size, Share & Trends Analysis Report By Product (RT-PCR Assay Kits), By Sample Type (Nasopharyngeal), By Mode (Centralized Testing), By End-use (Laboratories), By Region, And Segment Forecasts, 2024 – 2030 The global COVID-19 detection kits market size is expected to reach USD 4.06 billion by 2030, according to a new report by…

[mycarelabs01444]

My Care Labs offers quick, easy, and accurate RT-PCR testing for COVID-19, RSV, and Influenza A/B. We provide on-site testing at our lab and pop-up locations throughout California, with results available the same day or within 24 hours.