#NURIX

[bmv1]

Myntra co-founder Mukesh Bansal gets VC funding for new startup Nurix AI

Mukesh Bansal, the co-founder of online fashion major Myntra and Cult.fit, has secured $27.5 million in his new fundraising for artificial intelligence firm Nurix AI. This funding round combines seed investment and series A funding and was supported by Accel and General Catalyst.

Vision and Strategic Partnerships of Nurix AI

Nurix AI is primarily interested in offering AI-based customer communication tools. The kind of AI it seeks to incorporate into companies and organizations is to become functional agents within enterprises, boosting the effectiveness of their communication with an enterprise’s customers. Bansal believes that in the not-too-distant future, advanced intelligent agents supported by the human knowledge base will perform a great portion of work, generating unheard-of levels of efficiency and an increase in product quality.

Nurix AI intends to forge strategic collaborations with AI hardware and product makers. These partnerships help the company aim at the implementation of state-of-the-art AI technologies into the solutions, offering a competitive advantage in the market. Moreover, for Nurix AI, the improvement of the firm’s research & development functions will be vital so that its solutions remain cutting-edge in the field of AI. 

Funding Details

The $27.5 million raised shall play a critical role in accelerating the operations of Nurix AI. The collected funds will be utilized for the company’s improvement of its technological portfolio, strengthening research and development, and for the development of strategic collaborations with AI hardware and product providers. The strategic investment has been informed by the growing demand for artificial intelligence solutions across Asia & North America markets and its ability to address this space squarely will be strategic for Nurix AI.

Mukesh Bansal said, “At Nurix, we envision a future where AI agents, guided by human expertise, handle a significant portion of tasks, driving unprecedented gains in productivity and quality.” 

Entrepreneurial Journey of Mukesh Bansal

Mukesh Bansal co-founded Myntra in the same year and will be one of India’s most popular fashion e-tailers. Mukesh Bansal in 2014 managed to sell Myntra to his biggest rival Flipkart. Later, he started Curefit, a fitness services firm in 2021. It was renamed Cult.fit after receiving funding from Tata Digital. Mukesh Bansal was also the President of Tata Digital before he started his two-year sabbatical from the company in 2023.

Market Potential and Unique Approach

The overall AI market is rapidly growing and enterprises are choosing AI solutions more frequently to improve customer productivity and interaction. The market research shows that the AI market is projected to grow at a CAGR of 42.2% within the years 2020 to 2027. This growth of improvements in AI technology, growing investment, and the ever-growing need for AI solutions in various organizations.

Nurix AI has the opportunity to stand out as the company offering customer experience services enhanced by artificial intelligence, yet implemented jointly with human contributors. The first service offering is in the BPO sector and the company aims at helping enterprises have highly involved and productive conversations with their customers. With AI integration Nurix AI hopes to minimize the time and energy that customers have to spend interacting with the AI itself. 

Conclusion

The new startup founded by Mukesh Bansal, Nurix AI, will be the next major player in AI and customer engagement. After receiving $27.5 million in funding from Accel and General Catalyst, the firm is prepared for increased expansion of operations to meet demand. With the growth and development of Nurix AI, the field of customer interaction with companies through artificial intelligence will be influenced.

[nurixai]

Nurix AI

Product Name: GenAssist

Proof of Concept: GenAssist is a customized virtual assistant product based on Gen AI technology, designed to provide intelligent customer service and support for enterprises. With GenAssist, customers can get real-time and personalized help to meet their needs and solve problems, improve customer satisfaction and improve enterprise efficiency.

Product Features:

Real-time intelligent answers: GenAssist can use Gen AI technology to generate real-time, accurate answers and solutions based on the questions and needs provided by customers. Customers can get help without waiting for manual responses.

Personalized service: GenAssist can generate personalized suggestions and recommendations based on customers' historical data and personal preferences. By analyzing customers' preferences and behavior patterns, GenAssist can provide more accurate services.

Multi-channel support: GenAssist can flexibly integrate with multiple communication channels of enterprises, including website chat windows, in-app chat functions, and social media private messages, etc., to meet customer needs on different platforms.

Intelligent learning ability: GenAssist can continuously learn and optimize its answers and solutions, improve its intelligence level in continuous interaction, and better understand and meet customer needs.

Proof of concept method:

Build the GenAssist model: Based on the specific business needs of the enterprise, collect and prepare relevant data sets, and use OpenAI's technology platform to train the Gen AI model to generate intelligent customer answers and solutions.

Simulate customer scenario testing: Integrate GenAssist into the enterprise's customer service platform and simulate customer scenarios for testing. By interacting with simulated customers, verify whether GenAssist can accurately understand customer problems and provide real-time and personalized solutions.

User feedback and iteration: Collect user feedback and suggestions from simulated customer scenario testing, and continuously optimize GenAssist's performance and user experience. Through continuous iteration, ensure that GenAssist can meet customer needs and achieve the expected business results.

Through the above proof of concept process, enterprises can evaluate the feasibility and effectiveness of GenAssist and provide a basis for the development and launch of the final product.

[kkumarsblog]

Revolutionizing Disease Treatment with Molecular Glue Therapeutics

Molecular Glue Trials are emerging as a revolutionary advancement in targeted protein degradation (TPD). These small molecules have captured considerable attention in recent years due to their unique ability to modulate protein-protein interactions, thereby promoting the selective degradation of disease-associated proteins. Unlike traditional inhibitors that block protein activity, molecular glues enhance the interaction between ubiquitin ligases and target proteins, marking them for proteasomal degradation.

Understanding the Molecular Glue Mechanism of Action

Molecular glues function by stabilizing the interaction between an E3 ubiquitin ligase and the target protein. This stabilization enhances the recruitment of the target protein to the ubiquitin ligase complex, leading to ubiquitination and subsequent degradation via the proteasome. This mechanism provides several advantages over conventional small-molecule inhibitors, including improved specificity, reduced resistance development, and the ability to target previously "undruggable" proteins.

Key Molecular Glue Companies Driving Innovation

Several biotechnology and pharmaceutical companies are actively advancing molecular glue therapies. Notable players in the field include:

Arvinas: A pioneer in the targeted protein degradation space, working extensively on PROTACs and molecular glues.

C4 Therapeutics: Focused on TPD-based therapies for oncology and other conditions.

Monte Rosa Therapeutics: Developing molecular glue-based therapies for various cancer indications.

Kymera Therapeutics: Advancing novel degraders targeting key oncogenic pathways.

Nurix Therapeutics: Engaged in developing molecular glues and other small-molecule degraders for oncology and immune disorders.

These Molecular Glue Companies are conducting various preclinical and clinical studies to evaluate the safety and efficacy of molecular glues in diverse therapeutic areas.

Notable Molecular Glue Trials in Progress

Several promising molecular glue candidates are currently under clinical evaluation. Key ongoing trials include:

IBRUTINIB-BASED MOLECULAR GLUES FOR LYMPHOMA

Sponsor: C4 Therapeutics

Phase: I/II

Indication: B-cell malignancies

Description: This trial investigates a molecular glue designed to degrade Bruton's tyrosine kinase (BTK), offering a potential solution for patients resistant to standard BTK inhibitors.

CDK9-TARGETING MOLECULAR GLUES IN AML

Sponsor: Monte Rosa Therapeutics

Phase: I

Indication: Acute Myeloid Leukemia (AML)

Description: A first-in-human study assessing a CDK9-targeting molecular glue intended to induce leukemic cell death through targeted protein degradation.

MCL1-DEGRADING MOLECULAR GLUES IN SOLID TUMORS

Sponsor: Kymera Therapeutics

Phase: I/II

Indication: Solid tumors and hematologic malignancies

Description: This study aims to degrade MCL1, an anti-apoptotic protein often linked to tumor progression, to enhance cancer cell death.

Clinical Successes and Challenges

While molecular glue development has shown remarkable potential, the transition from preclinical success to clinical efficacy presents challenges:

Drug Delivery and Bioavailability: Poor solubility and bioavailability are common hurdles, requiring improved formulation techniques.

Target Selectivity: Achieving high specificity to minimize off-target effects is essential for reducing toxicity risks.

Resistance Mechanisms: Prolonged treatment may induce resistance through mutations in the target protein or E3 ligase.

Regulatory Barriers: As a novel drug class, molecular glues require stringent regulatory evaluation to ensure safety and efficacy.

Despite these challenges, advancements in medicinal chemistry and AI-driven drug discovery continue to refine molecular glue candidates, improving potency and selectivity.

Future Prospects for Molecular Glue Therapies

The future of molecular glue therapies is promising, with several exciting trends shaping the field:

Combination Therapies: Molecular glues are being tested alongside immunotherapies, chemotherapy, and other targeted drugs to boost treatment effectiveness.

Expanded Indications: While oncology dominates current trials, molecular glues are also being explored for neurodegenerative diseases such as Alzheimer's and Parkinson's.

AI-Powered Drug Discovery: Artificial intelligence and machine learning are accelerating the identification of novel molecular glue candidates with optimized properties.

Personalized Medicine: Advances in genomics and proteomics are enabling tailored molecular glue therapies based on individual patient profiles.

Conclusion

Molecular glue trials are at the forefront of transforming targeted protein degradation, offering innovative therapeutic options for previously untreatable conditions. With multiple clinical trials underway and increasing investments from biotechnology and pharmaceutical companies, these molecules hold significant potential in revolutionizing precision medicine. As ongoing research advances the understanding of Molecular Glue Mechanism of Action, these therapies are expected to become vital tools in combating cancer, neurodegenerative diseases, and autoimmune conditions.

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Contact InformationKanishk Email: kkumar@delveinsight.com

[wakeming]

'Holiday Witch Business: A Black Cat's View'

I used to be a solo cat. Now I live with Fiona and Jenny. They call me Nurix.

We met at the edge of the woods during a beautiful autumn sunset. Everything glowed with warm orange: the sky, the leaves, the wind, even some abandoned iron.

'Do you want to live with us?' They petted me softly with their gentle hands.

'Come, come.' The invitation felt natural.

We've been together for 189 days. They give me really good snacks, but I'm still an independent cat.

I found out that they are witches, so I guess I'm now a witch's cat, but I don't do magic.

They perform magic a lot—with accessories, with machines, sometimes with spells—causing lights and sounds to come out of nowhere.

I'm involved in all their business.

'Where we goin' this time for the holiday?' Fiona asked, one day.

'What about the beach?' Jenny said, reading a book.

So we flew here.

Sunbeams, sea breeze, golden sands, and big trees growing tasty seaweeds.

They are doing their holiday witch business on the beach.

As usual, I like hanging on Jenny's fluffy head.

Being independent and being present, I'd choose to stick with them longer and longer, I guess.

[mirrorworldmagazine]

Mukesh Bansal’s Nurix AI Secures $27.5 Million in Funding from Leading Venture Firms – Accel, General Catalyst, and Meraki Labs

San Francisco, CA – Mukesh Bansal’s Nurix AI has raised $27.5 million in funding from General Catalyst and Accel, with Meraki Labs, in its most recent fundraising round, which is a major step forward for the nascent field of artificial intelligence and healthcare. The investment, led by major venture capital firms Accel and General Catalyst, with investments from Meraki Labs, demonstrates the growing interest in AI-powered solutions for drug development and personalized treatment.

Nurix AI, founded in 2021, intends to transform pharmaceutical development by using advanced machine learning algorithms to predict how tiny compounds will interact with proteins in the human body. The company’s novel approach aims to speed up the drug discovery process, which has typically taken years and requires significant financial commitment.

The funding is a combination of seed and series A rounds. The company raised $12.5 million in early capital, with the remainder coming from Series A.

The investment will be used to enhance Nurix’s technological base and scale its activities in Asia and Northern America, according to a news release. This involves expanding its R&D skills and forming long-term relationships with AI hardware and product companies.

Transforming Drug Discovery

Mukesh Bansal, who co-founded the well-known firm Myntra before delving into the area of AI and biotech, is optimistic about Nurix AI’s ability to transform the pharmaceutical landscape. “Traditional drug discovery strategies are time-consuming and uncertain. “Our technology enables researchers to make more informed decisions earlier in the process, ultimately saving time and resources,” he explained in a recent interview.

Nurix AI’s technology uses cutting-edge deep learning techniques to scan large datasets, identifying possible medication candidates more accurately than traditional methods. Nurix AI’s algorithms predict drug efficacy and safety by combining biological, chemical, and clinical data, considerably increasing the likelihood of favorable clinical trial outcomes.

Read More: https://mirrorworldmagazine.com/mukesh-bansals-nurix-ai-secures-27-5-million-in-funding-from-leading-venture-firms-accel-general-catalyst-and-meraki-labs/

[businessindustry]

Molecular Glues Market Application, Growth 2024-2032

The Reports and Insights, a leading market research company, has recently releases report titled “Molecular Glues Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2024-2032.” The study provides a detailed analysis of the industry, including the global Molecular Glues Market Size share, trends, and growth forecasts. The report also includes competitor and regional analysis and highlights the latest advancements in the market.

Report Highlights:

How big is the Molecular Glues Market?

According to Reports and Insights analysis, the global molecular glues market is expected to register a revenue CAGR of 5.8% during the forecast period of 2024-2032.

What are Molecular Glues?

Molecular glues are small molecules capable of binding to two different proteins simultaneously, thereby effectively "gluing" them together. This characteristic enables them to modulate interactions between proteins, influencing various cellular functions. Molecular glues have garnered considerable interest in drug discovery and development because they can target protein complexes that are difficult to inhibit using conventional methods. They present a promising strategy for creating new treatments for diseases like cancer, neurodegenerative disorders, and viral infections, by selectively targeting specific protein interactions crucial for the advancement of these conditions.

Request for a sample copy with detail analysis: https://www.reportsandinsights.com/sample-request/1609

What are the growth prospects and trends in the Molecular Glues industry?

The molecular glues market growth is driven by various factors. The molecular glues market is experiencing significant growth, primarily due to the increasing emphasis on drug discovery and development. Molecular glues are essential for modulating interactions between proteins, making them invaluable in addressing complex diseases. Factors such as the rising incidence of chronic diseases, growing demand for targeted therapies, and advancements in molecular biology are propelling market expansion. Moreover, the rising investment in research and development focused on molecular glues is expected to drive further market growth. Hence, all these factors contribute to molecular glues market growth.

What is included in market segmentation?

The report has segmented the market into the following categories:

By Product Type:

Proteolysis-Targeting Chimeras (PROTACs)

Specific and Nongeneric Protein Degraders

Other Molecular Glues

Application:

Oncology

Genetic Disorders

Neurological Disorders

Infectious Diseases

Other Therapeutic Areas

End-user:

Pharmaceuticals and Biotechnology Companies

Research Institutes and Academia

Contract Research Organizations (CROs)

Others

Research Focus:

Preclinical Studies

Clinical Trials

Post-market Surveillance

Segmentation By Region:

North America:

United States

Canada

Europe:

Germany

The U.K.

France

Spain

Italy

Russia

Poland

BENELUX

NORDIC

Rest of Europe

Asia Pacific:

China

Japan

India

South Korea

ASEAN

Australia & New Zealand

Rest of Asia Pacific

Latin America:

Brazil

Mexico

Argentina

Middle East & Africa:

Saudi Arabia

South Africa

United Arab Emirates

Israel

Who are the key players operating in the industry?

The report covers the major market players including:

Arvinas Inc.

C4 Therapeutics

Kymera Therapeutics

Nurix Therapeutics

Bristol Myers Squibb

Boehringer Ingelheim

AstraZeneca

Genentech (a member of the Roche Group)

GlaxoSmithKline

Novartis

Pfizer Inc.

Takeda Pharmaceuticals

Merck & Co., Inc.

Amgen Inc.

Vertex Pharmaceuticals

View Full Report: https://www.reportsandinsights.com/report/Molecular Glues-market

If you require any specific information that is not covered currently within the scope of the report, we will provide the same as a part of the customization.

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Reports and Insights consistently mееt international benchmarks in the market research industry and maintain a kееn focus on providing only the highest quality of reports and analysis outlooks across markets, industries, domains, sectors, and verticals. We have bееn catering to varying market nееds and do not compromise on quality and research efforts in our objective to deliver only the very best to our clients globally.

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[fmarkets]

'''Urgent'Measures'Required'to'Reverse'the'Financial'Downturn'at'Nurix'Therapeutics'Inc $NRIX #Nasdaq

NRIX announced second quarter of 2024 operating shortfall of $-48.54 millionInterpreting the financial results of a major pharmaceutical preparations company can be both enlightening and concerning. In the case of Nurix Therapeutics Inc, the disclosed figures for the period of March to May 31, 2024, paint a rather disastrous picture. Revenue has experienced a significant decline of -60.582% to $12.09 million, while the net loss per share has widened to $-0.71. Comparing these results to the same financial reporting period a year ago, it

[hopetribune]

Chronic Lymphocytic Leukemia Market Is Projected to Grow at a Moderate Growth Rate During the Forecast Period | Loxo Oncology, Oncternal Therapeutics, MingSight Pharmaceuticals, Nurix Therapeutics

http://dlvr.it/T6WKyK

[conversationpoint]

Chronic Lymphocytic Leukemia Market Anticipated to Expand by 2032, as Projected by DelveInsight | Loxo Oncology, Oncternal Therapeutics, Novartis, AstraZeneca, Nurix Therapeutics, Merck

http://dlvr.it/T5ZRms

[thealphareporter]

CNS Lymphoma Pipeline Analysis (2023) Covering Clinical Trials, Emerging Therapies, FDA, EMA, and PMDA Approvals, Competitive Landscape | Kazia Therapeutics, Cellectar, Ono Pharma, Nurix Therapeutics

http://dlvr.it/SyZy8n

[biotech-news-feed]

The alliance, which aims to combine Seagen’s antibody expertise with Nurix’s targeted protein degradation research, comes as the larger biotech awaits its acquisition by Pfizer to close. #BioTech #science

[lindamacdonaldavanir]

Seagen partners with Nurix to create new kind of cancer drug

Seagen partners with Nurix to create new kind of cancer drug https://ift.tt/rZ3xDRJ The alliance, which aims to combine Seagen’s antibody expertise with Nurix’s targeted protein degradation research, comes as the larger biotech awaits its acquisition by Pfizer to close.  via BioPharma Dive - Latest News https://ift.tt/qcQsv09 September 07, 2023 at 12:20PM

[columbianewsupdates]

CNS Lymphoma Market is Expected to Expand at a Healthy Growth Rate During the Forecast Period (2022-2032),|Key Companies – Pentixa Pharmaceuticals, Ono Pharmaceuticals, Prelude Therapeutics, Nurix Ther

http://dlvr.it/SnkvMn

[kkumarsblog]

Molecular Glues Market Evolution: Key Players and Growth Projections

The Molecular Glues Market is witnessing remarkable growth, driven by their potential in revolutionizing targeted protein degradation and addressing previously undruggable targets. Molecular glues are small molecules that induce protein-protein interactions, enabling targeted protein degradation for conditions like cancer, autoimmune diseases, and other complex disorders.

Market Overview: Molecular Glues Landscape

The Molecular Glues Market Size has expanded significantly with growing research investments and technological advancements. Pharmaceutical companies are actively exploring molecular glues to unlock new therapeutic strategies, particularly in oncology and immunology.

Key Players in the Molecular Glues Market

Prominent Molecular Glues Companies driving innovation and expanding product pipelines include:

C4 Therapeutics

Kymera Therapeutics

Arvinas, Inc.

Monte Rosa Therapeutics

Nurix Therapeutics

These companies are leveraging molecular glue technology to develop advanced therapies targeting diverse protein classes, enhancing treatment precision.

Emerging Therapies and Drug Innovations

The Molecular Glues Drugs Market is evolving with groundbreaking drug candidates aimed at improving clinical outcomes in conditions with limited treatment options. Ongoing clinical trials are exploring combination therapies, precision targeting, and improved formulations to boost efficacy and safety.

Future Outlook and Market Dynamics

The Molecular Glues Therapeutics Market is poised for exponential growth, fueled by increasing collaborations, rising investment in protein degradation research, and promising clinical data. As precision medicine continues to advance, molecular glues are expected to play a critical role in developing innovative therapies for hard-to-treat diseases.

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About DelveInsight

DelveInsight is a leading market research and consulting firm specializing in the life sciences and healthcare sectors. With a focus on providing actionable insights, DelveInsight empowers pharmaceutical, biotech, and medical device companies to make informed decisions in competitive and evolving markets.

Contact InformationKanishk kkumar@delveinsight.com

[craftgender]

ADnurix:

A gender that is caused by the Attention Deficit in ADHD.

This gender is basically “Executive Dysfunction: Gender Edition”. It’s somewhere in the brain fog. You just don’t know where it is just yet. The gender was just here a second ago, I’ll find it, I swear.

This term can only be used by people with ADHD

Coined By: @term-hoarder