#Megathura crenulata

[animalids]

Giant keyhole limpet (Megathura crenulata)

Photo by Robyn Waayers

[hardtigerdreamlands]

Megathura crenulata is a northeastern Pacific Ocean mollusk species in the family Fissurellidae

NATIONAL GEOGRAPHIC

[boudhabar]

Megathura crenulata

[andrearrrrr]

Megathura Crenulata (Giant keyhole limpet) is a Northeastern Pacific Ocean species of limpet. They consume plants, red and brown algae. Their blood appears blue due to its copper content.

https://en.wikipedia.org/wiki/Megathura_crenulata

[deinheilpraktiker]

Studentenjob: Urlaubsvertretung als Front und Customer Relationship Manager (m/w/d)

Studentenjob: Urlaubsvertretung als Front und Customer Relationship Manager (m/w/d)

Ort: Baden-Württemberg Beschreibung:Die biosyn Arzneimittel GmbH ist ein Pharma- und Biotech-Unternehmen, spezialisiert auf Spurenelemente, Weltmarktführer bei hochdosierten Selen-Injektionen, Entwickler und Betreiber von 2 weltweit einmaligen GMP-Wirkstoff-Fertigungen und außerdem im Biotech-Bereich aktiv mit einem Glykoprotein, isoliert aus der Megathura crenulata, einer in Kalifornien…

[moleculardepot]

Keyhole Limpet Hemocyanin (KLH)

Keyhole Limpet Hemocyanin (KLH)

Keyhole Limpet Hemocyanin (KLH) Catalog number: B2010482 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 5 mg Molecular Weight or Concentration: 4 MDa Supplied as: Liquid Solution Applications: a strong immune-stimulant Storage: 2-8°C Keywords: KLH, Hemocyanin from Megathura crenulata Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I…

[aparnasonali-blog]

The Next five years the Keyhole Limpet Hemocyanin (KLH) market will register a 2.0% CAGR

Acquire Market Research has announced market research Report On – “Global Keyhole Limpet Hemocyanin (KLH) Market Growth 2019-2024″ with key players.

This report studies the Keyhole Limpet Hemocyanin (KLH) market, KLH, which can be used as an active pharmaceutical ingredient (“API”), is a very large, high molecular weight, oxygen-carrying glycoprotein made of millions of atoms. There are two KLH subunit forms, KLH1 and KLH2, each composed of seven or eight functional units, with each functional unit having an oxygen binding site of two copper atoms. Keyhole limpet hemocyanin is an extremely large, heterogeneous glycosylated protein consisting of subunits with a molecular weight of 350,000 and 390,000 in aggregates with molecular weights of 4,500,000-13,000,000. Each domain of a KLH subunit contains two copper atoms that together bind a single oxygen molecule (O2). The KLH protein is potently immunogenic yet safe in humans and is therefore highly prized as a vaccine carrier protein.

KLH protein is derived only from the hemolymph of the giant keyhole limpet (megathura crenulata), which is native only to a limited stretch of the Pacific Ocean coastline along Southern California and Baja California, Mexico.

KLH can be used as an active pharmaceutical ingredient and has high medical value. Due to high technology barrier and scarce raw material, there are few companies able to produce KLH and biosyn highly monopolizes the market at the moment.

The global keyhole limpet hemocyanin production will increase to 2132g in 2017, from 1570g in 2012, it is estimated that the global keyhole limpet hemocyanin demand will develop with a CAGR of 4.03% in the coming five years.

Megathura crenulata is native to rocky coasts of Southern California, United States to Baja California, Mexico and are found at shallow depths below the low tide line. American companies dominate the keyhole limpet hemocyanin product market. But downstream demand of keyhole limpet hemocyanin mainly is concentrated in Europe. Owning to immature technology, there is no company in China produce KLH for the time being.

Get Full Sample Copy @ https://www.acquiremarketresearch.com/sample-request/459

According to this study, over the next five years the Keyhole Limpet Hemocyanin (KLH) market will register a 2.0% CAGR in terms of revenue, the global market size will reach US$ 10 million by 2024, from US$ 9 million in 2019. In particular, this report presents the global market share (sales and revenue) of key companies in Keyhole Limpet Hemocyanin (KLH) business.

This report presents a comprehensive overview, market shares, and growth opportunities of Keyhole Limpet Hemocyanin (KLH) market by product type, application, key manufacturers and key regions and countries.

This study considers the Keyhole Limpet Hemocyanin (KLH) value and volume generated from the sales of the following segments:

Segmentation by product type

   GMP/Clinic Grade

   Research Grade

Segmentation by application

   Laboratory

   Pharmaceuticals

 More Info and TOC @ https://www.acquiremarketresearch.com/industry-reports/global-keyhole-limpet-hemocyanin-klh-market-growth-2019-2024/459/

This report also splits the market by region

   Americas ( United States ,Canada, Mexico, Brazil)

   APAC   ( China, Japan, Korea ,Southeast Asia ,India ,Australia)

   Europe   ( Germany ,France, UK  ,Italy ,Russia Spain)

   Middle East & Africa  (Egypt, South Africa,  Israel ,Turkey ,GCC Countries) 

The key manufacturers covered in this report

   Biosyn

   Sigma-Aldrich

   Stellar Biotechnologies

   Thermo Fisher Scientific

   G-Biosciences

Research objectives

 To study and analyze the global Keyhole Limpet Hemocyanin (KLH) consumption (value & volume) by key regions/countries, product type and application, history data from 2014 to 2018, and forecast to 2024.

   To understand the structure of Keyhole Limpet Hemocyanin (KLH) market by identifying its various subsegments.

   Focuses on the key global Keyhole Limpet Hemocyanin (KLH) manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.

   To analyze the Keyhole Limpet Hemocyanin (KLH) with respect to individual growth trends, future prospects, and their contribution to the total market.

   To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).

   To project the consumption of Keyhole Limpet Hemocyanin (KLH) submarkets, with respect to key regions (along with their respective key countries).

   To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.

   To strategically profile the key players and comprehensively analyze their growth strategies.

 Table of Contents:

1 Scope of the Report

   1.1 Market Introduction

   1.2 Research Objectives

   1.3 Years Considered

   1.4 Market Research Methodology

   1.5 Economic Indicators

   1.6 Currency Considered

 2 Executive Summary

   2.1 World Market Overview

       2.1.1 Global DL-Dithiothreitol (DTT) Consumption 2014-2024

       2.1.2 DL-Dithiothreitol (DTT) Consumption CAGR by Region

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[itsbydesign]

There are two keyhole limpet hemocyanin genes, termed KLH1 and KLH2 which share around 60% identity at the protein level. Both encode large glycosylated proteins consisting of around 3400 amino acids and a molecular weight of around 390,000 Daltons, excluding the glycosylation. The protein oligomerises to form a barrel shaped didecameric complex which is composed of 20 monomers. Each domain of a KLH subunit contains two copper atoms that together bind a single oxygen molecule (O2). When oxygen is bound to hemocyanin, the molecule takes on a distinctive transparent, opalescent blue color, due to the Cu2+ state of the copper. In the absence of oxygen, the bound copper is found as Cu1+ and hemocyanin is colorless. The KLH protein is potently immunogenic, but does not cause an adverse immune response in humans. It is therefore highly prized as a vaccine carrier protein. Because of its size and glycosylation, KLH protein cannot be reproduced synthetically; it is available only as a purified biological product from the keyhole limpet Megathura crenulata.

[astronomy-to-zoology]

Great Keyhole Limpet (Megathura crenulata)

Also known as the giant keyhole limpet, the great keyhole limpet is a large species of keyhole limpet (a type of gastropod) native to the coasts of Southern California and Mexico. Like other limpets the giant keyhole limpet is a simple herbivore and feeds mostly on algae and detritus. True to their name great keyhole limpets have a single keyhole like opening on the tops of their shells, this hole allows water to enter the animal and waste leave it. Most of this large limpets shell is covered in its fleshy mantle.

Phylogeny

Animalia-Mollusca-Gastropoda-Vetigastropoda-Fissurellidae-Fissurellidae-Megathura-crenulata

Image Source(s)

[boudhabar]

Megathura crenulata

[deinheilpraktiker]

Studentenjob: Urlaubsvertretung als Front und Customer Relationship Manager (m/w/d)

Studentenjob: Urlaubsvertretung als Front und Customer Relationship Manager (m/w/d)

Ort: Baden-Württemberg Beschreibung:Die biosyn Arzneimittel GmbH ist ein Pharma- und Biotech-Unternehmen, spezialisiert auf Spurenelemente, Weltmarktführer bei hochdosierten Selen-Injektionen, Entwickler und Betreiber von 2 weltweit einmaligen GMP-Wirkstoff-Fertigungen und außerdem im Biotech-Bereich aktiv mit einem Glykoprotein, isoliert aus der Megathura crenulata, einer in Kalifornien…

[gastropods]

that hole on top of the shell is where it poops out of :) unlike "true limpets" which release their waste underneath the shell

Giant keyhole limpet (Megathura crenulata)

Photo by Robyn Waayers

[boudhabar]

Megathura crenulata 

[boudhabar]

Megathura crenulata

[boudhabar]

Megathura crenulata

[boudhabar]

Megathura crenulata