#IP 10 mg

[aingopharma]

Dydrogesterone Tablet IP 10 mg is a synthetic hormone widely used in hormone replacement therapy (HRT) and other gynecological treatments. This medication mimics the effects of the natural hormone progesterone, playing a crucial role in regulating menstrual cycles and maintaining pregnancy. In this article, we’ll dive into the uses, benefits, dosage guidelines, and potential side effects of Dydrogesterone Tablet IP 10 mg. Whether you’re dealing with menstrual irregularities, endometriosis, or infertility issues, understanding how this medication works can help you make informed decisions about your reproductive health.

[meds4genonline]

Find new post

https://businesshonchos.in/2024/08/15/10-best-ways-to-boost-libido-naturally/

[jualthermaloil-blog]

BURNER RIELLO RLS 500 M-RLS 650-RLS 800-RLS 1000-RLS 1200 M

Jual Burner Riello Dual Fuel RLS 500 M- RLS 1200 M

  Burner Riello Seri RLS satu jenis burner dual fuel yang memiliki desain ukuran besar beropasai dengan dua api atau Modulating progresive, burner seri ini memiliki ciri has berbentuk sperti kuda kokoh berwarna merah pada body dan sistem kontrol maunpun safty yang terjamin. adapun riello burner seri RLS /M di bagi menjadi 5 model yaitu . Riello RLS 500/M,  RLS 650/M, Riello RLS 800/M, Riello RLS 1000/M, Riello RLS 1200 /M. Riello merupakan kompor burner produksi itali yang memiliki populasi besar di beberapa negara industri di dunia salah sataunya indonesia, selain itu suku cadang dan after service  riello yang baik. kami perusahaan indira mitra boiler salah satu mitra burner riello sejak tahun 2015 yang memiliki komitmen mempertahankan kualitas produk dan ketersedian unit , suku cadang maupun layanan service  yang tepat dan cepat.

Spesifikasi  Riello RLS 500 /M Hingga RLS 1200/ M

Burner RLS/M dicirikan oleh struktur monoblok modular yang berarti semua komponen yang diperlukan dapat digunakan digabungkan dalam satu unit sehingga membuat pemasangan lebih mudah, cepat, dan yang terpenting, lebih fleksibel. Seri ini mencakup rentang pembakaran dari 2500 hingga 11500 kW, dan telah dirancang untuk digunakan pada boiler air panas, ketel air yang terlalu panas serta ketel uap. Pengoperasiannya dapat berupa “progresif dua tahap” atau alternatifnya “modulasi”, baik untuk bahan bakar, minyak ringan maupun gas, dengan pemasangan regulator logika PID. Perangkat pengaturan kamera mekanis memungkinkan untuk mengejar rasio modulasi tinggi pada semua rentang laju pengaktifan. Itu Oleh karena itu, pembakar dapat memasok daya yang dibutuhkan dengan presisi, sehingga menjamin tingkat sistem efisiensi yang tinggi dan pengaturan stabilitas, memperoleh konsumsi bahan bakar dan pengurangan biaya pengoperasian. Kepala pembakaran menjamin pengurangan emisi polusi (NOx < 80 mg/kWh pada pengoperasian gas). Eksklusif desain menjamin emisi suara yang rendah, konsumsi listrik yang rendah, penggunaan dan perawatan yang mudah. Seri Riello Dual Fuel RLS /M - RLS 500/M MX 1120/2500 ÷ 5050 kW - RLS 650/M MX 1430/3000 ÷ 6550 kW - RLS 800/M MX 1750/3500 ÷ 8000 kW - RLS 1000/M MX 1200/3750 ÷ 10600 kW - RLS 1200/M MX 1500/5500 ÷ 11500 kW   Data Teknik Riello RLS 500/M- RLS 1200/M - Burner operation : mode Progressive two-stage or modulating - Modulation ratio at max. output : 4 ÷ 1 - Servomotor type : SQM 10.1 - run time s : 42s / 130° - Heat output : 1120/2500 ÷ 5050 - 1430/3000 ÷ 6550 - 1750/3500 ÷ 8000 kW - Working temperature : max. 0/50 °C /min - Light oil :net calorific value 11.86 kWh/kg - viscosity at 20°C (cSt) 4 ÷ 6 mm2/s - output : 95/211 - 425 121/253 - 552 148/295 - 675 kg/h - Pump type : TA5 - output 560 kg/h (at 16.5 bar) - Atomised pressure : 6 - 30 bar - Fuel temperature max. : 140 °C - Fuel pre-heater : NO - G20 gas : net calorific value 10 kWh/Nm3 - gas delivery : 112/250 ÷ 505 143/300 ÷ 655 175/350 ÷ 800 Nm3/h - G25 gas : net calorific value 8.6 kWh/Nm3 - LPG gas : net calorific value  -- 25.8 kWh/Nm3 - Fan type : Forward curve blades - Air temperature max : 60 °C - Electrical supply Ph/Hz/V : 3/400/50 (±10%) 3N/400/50 (±10%) - Auxiliary electrical supply Ph/Hz/V : 1/230/50 ~ (±10%) 1/230/50 ~ (±10%) - Control box type : LFL 1.333 - Total electrical power kW: 15.8 (oil) / 14 (gas) 22.5 (oil) / 20.8 (gas) 24.8 (oil) / 23 (gas) - Fan motor electrical power : 12 18.5 21 kW - rated current : A 21.2 - 12.2 35.7 - 20.6 41.8 - 24.2 - Pump motor electrical power kW : 1.5 - rated current : A 5.9/3.4 - start up current : A 7 x In - protection level : IP 54 - Ignition transformer : V1 - V2 230V - 2 x 5 kV 230V - 1 x 8 kV I1 - I2 1.9 A - 35 mA 1 A - 20 mA Seri Burner RLS /M

BURNER MODELS                  HEAD LENGHT             FLAME CONTROL ELECTRICAL AUXILIARY     SYSTEM SUPPLY VOLTAGE RLS 500/M MX TC FS1 3/400/50 230/50-60 RLS 650/M MX TC FS1 3/400/50 230/50-60 RLS 800/M MX TC FS1 3/400/50 230/50-60 RLS 1000/M C13 TC FS1 3N/400/50 230/50-60 RLS 1200/M C13 TC FS1 3N/400/50 230/50-60 Pembakar bahan bakar ganda draft paksa monoblock dengan operasi modulasi, otomatis penuh, terdiri dari: - Kipas berperforma tinggi - Sirkuit penghisap udara dilapisi bahan kedap suara - Peredam udara untuk pengaturan udara yang dikendalikan oleh motor servo presisi tinggi -  Saklar tekanan udara - Motor start kipas pada 2800 rpm, tiga fase, 400V, 50Hz - Head pembakaran rendah emisi, yang dapat diatur berdasarkan output yang dibutuhkan, dilengkapi dengan: - Ujung kerucut berbahan stainless steel, tahan terhadap korosi dan suhu tinggi - elektroda pengapian untuk RLS 500 - pengapian oleh pilot gas dengan kereta gas untuk model RLS 650 - 800 - 1000 - 1200 - disk stabilitas api - Pembakar bahan bakar ganda RLS 1000-1200/M dilengkapi dengan tombak semprot untuk oli ringan, diaktifkan dengan kompresiUdara (kompresor udara tidak termasuk)

Suku Cadang Peralatan Burner

Standard equipment: - 1 flange gasket - 4 screws for fixing the flange - 1 thermal screen - 4 screws for fixing the burner flange to the boiler - 2 flexible pipes for connection to the oil supply network - 2 nipples for connection to the pump with gaskets - Seal control pressure switch (for installation on gas train) - Instruction handbook for installation, use and maintenance - Spare parts catalogue. Gas train : Fuel supply line, in the MULTIBLOC configuration (for a diameter of 1-1/2” and 2”) or COMPOSED configuration (from a diameter of DN 65 until a diameter of DN 125), fitted with: - Filter - Stabiliser - Minimum gas pressure switch - Safety valve - One stage working valve with ignition gas output regulator. Conforming to: - 2004/108 EC directive (electromagnetic compatibility) - 2006/95 EC directive (low voltage) -  2006/42 EC directive (machine) - 2009/142 EC directive (gas) - EN 676 (gas burners) - EN 267 (light oil burners). Available accessories to be ordered separately: - RWF 50 power controller - Temperature probe -100/+500 °C - Pressure probe 0-2.5 bar - Pressure probe 0-16 bar - Pressure probe 0-25 bar - Analog control signal converter - Potentiometer kit for servomotor - Continuous ventilation kit - UV cell kit - PC interface kit - Sound proofing box - Spacer - Adapters - Stabiliser spring - Seal control

Fitur Unggulan Riello Seri RLS 500/M- 1200/M

Pembakar bahan bakar ganda draft paksa monoblock dengan operasi modulasi, otomatis penuh, terdiri dari ,Kipas berperforma tinggi , Sirkuit penghisap udara dilapisi bahan kedap suara, Peredam udara untuk pengaturan udara yang dikendalikan oleh motor servo presisi tinggi, Saklar tekanan udara, Motor start kipas pada 2800 rpm, tiga fase, 400V, 50Hz, Head pembakaran rendah emisi, yang dapat diatur berdasarkan output yang dibutuhkan, dilengkapi dengan, Ujung kerucut berbahan stainless steel, tahan terhadap korosi dan suhu tinggi, elektroda pengapian untuk RLS 500, pengapian oleh pilot gas dengan kereta gas untuk model RLS 650 - 800 1000 - 1200, disk stabilitas api, Cam mekanis dengan modulator gas dan oli . Sakelar tekanan gas maksimum, dengan titik uji tekanan, untuk menghentikan pembakar jika terjadi tekanan berlebih pada jalur pasokan bahan bakar, Panel kontrol api untuk mengendalikan keamanan sistem - Detektor api inframerah, Starter bintang/segitiga untuk motor kipas - Papan terminal suplai listrik utama, Saklar nyala/mati pembakar, Sinyal led tegangan tambahan, Sinyal led burner berfungsi, Kontak motor dan relai termal dengan tombol pelepas, Perlindungan termal internal motor, Sinyal led kegagalan motor, Sinyal led kegagalan burner dan tombol pelepas menyala, Tombol darurat, Sambungan colokan-soket, Engsel pembuka pembakar, Cincin pengangkat, Tingkat perlindungan listrik IP 54. Pompa roda gigi oli ringan untuk suplai bahan bakar bertekanan tinggi, Motor starter pompa khusus, Sistem katup dengan katup pengaman oli ganda pada sirkuit keluaran dan katup pengaman ganda pada sirkuit balik, Sakelar tekanan oli maksimum dan minimum , Pengukur tekanan oli pada jalur suplai dan pengembalian oli , Pemilih Minyak/Gas, Jendela inspeksi api, Pembakar bahan bakar ganda RLS 1000-1200/M dilengkapi dengan tombak semprot untuk oli ringan, diaktifkan dengan kompresi, Udara (kompresor udara tidak termasuk)

Layanan Produk Riello

Memilih merek dan jenis burner pada suatu mesin industri di perlukan analisa yang memadai sesuai kebutuhan dan lingkungan pengoprasian, kami selaku stockis burner riello di indonesia juga menyedikan jasa konsultasi/diskusi terkait produk riello di sluruh wilayah indonesia indo lebih lanjut bisa hubungi marketing kami di bawah ini : PT Indira Mitra Boiler Jln. LoveBird blok D19/21 RT12 RW005 Permata Sepatan,Pisangan jaya ,Sepatan, Kab. Tangerang, Banten-15520 ZAENAL ARIFIN Sales Engineer Phone : (021) 59375021 Mobile : 081385776935 Whatshap : 081385776935 Email : idmarifin2@gmail.com Email : arifinspi2023@gmail.com Read the full article

[peptidehub]

Exploring PNC-27: Mechanisms and Research Potential

Introduction to PNC-27

Immunotherapeutic agents have long been investigated as alternative treatments for cancer, with a growing body of research highlighting their safety compared to traditional methods like radiotherapy and chemotherapy. This is primarily because immunotherapy leverages the body's own defense mechanisms rather than introducing harmful chemicals. Among the promising immunotherapeutic peptides are PNC-27 and PNC-28, developed by a supercomputer at SUNY Downstate Medical Center in 2000. These peptides interact with the MDM2-p53 tumor suppressor complex, acting as competitive inhibitors to increase the half-life of p53 and facilitate the elimination of cancer cells.

Mechanism of Action

Targeting HDM-2 in Cancer Cells

Cancer cells often have HDM-2 present in their cell membranes. When PNC-27 is administered, it targets these HDM-2 molecules. By binding to them, PNC-27 creates pores or holes in the cancer cell membranes, leading to their destruction. This mechanism selectively induces cell death in cancerous cells while sparing normal cells.

Research Highlights

Study 1: PNC-27 and Tumor Cell Lysis

Purpose:This study aimed to determine whether the intact PNC-27 peptide or its critical fragments induce pore formation in cancer cells.

Methods: PNC-27 was labeled with green and red fluorescent markers and introduced to MCF-7 breast cancer cells and untransformed MCF-10-2A breast epithelial cells. The fluorescence patterns were observed to determine the peptide's integrity and activity.

Results:Within 30 minutes, significant combined yellow fluorescence, indicating the intact peptide, was observed in the membranes of cancer cells, which increased during cell lysis. In contrast, untransformed cells showed initial uniform yellow fluorescence that disappeared over time, with these cells remaining viable.

Conclusions: PNC-27 induces cancer cell membrane lysis as an intact peptide, not as fragments. The observed fluorescence patterns suggest specific interactions with intramembrane targets in cancer cells, which do not exist in untransformed cells, highlighting the peptide's selective action.

Study 2: Binding Conformation and Selectivity

Purpose:To investigate how PNC-27 kills cancer cells by binding to HDM-2 in their membranes.

Methods:The 3D structure of PNC-27 was compared with the structure of p53 residues bound to HDM-2. The presence of HDM-2 in various cancer cells' membranes and its colocalization with PNC-27 was examined. Additionally, untransformed cells were transfected with HDM-2 to assess their susceptibility to PNC-27.

Results: PNC-27 targets HDM-2 in cancer cell membranes, inducing membranolysis. Untransformed cells expressing membrane-bound HDM-2 became susceptible to PNC-27, confirming the peptide's selectivity.

Conclusions: PNC-27 selectively induces cancer cell lysis by targeting HDM-2 in their membranes. This specificity offers a promising approach for cancer treatment, minimizing harm to normal cells.

Study 3: PNC-27 in an Intraperitoneal Mouse Model

Objectives:To evaluate PNC-27's cytotoxic effects on the SKOV3-luc-D3 ovarian cancer cell line in vitro and its maximum tolerated dose (MTD) in vivo using a mouse model.

Methods:SKOV3-luc-D3 cells were cultured and treated with PNC-27, and cytotoxicity was assessed using MTT and LDH assays. In vivo, healthy and tumor-bearing mice received daily intraperitoneal (IP) injections of PNC-27 to determine the MTD and assess toxicity.

Results: PNC-27 effectively suppressed cell proliferation and was cytotoxic in vitro. The MTD in mice was 2 mg/day, with dose-limiting toxicities observed at higher doses. Tumor-bearing mice tolerated treatment at the MTD, with histopathological assessments confirming these findings.

Conclusions: PNC-27 exhibits cytostatic and cytotoxic effects on ovarian cancer cells in vitro and is well-tolerated at therapeutic doses in vivo. Future studies will focus on using bioluminescent imaging to monitor tumor response without sacrificing the animals.

Study 4: Ex Vivo Efficacy Against Patient-Derived Ovarian Cancer

Objective:To evaluate the efficacy of PNC-27 against primary cultures of epithelial ovarian cancer cells from patients.

Methods:Primary cancer cells were isolated from patients and characterized in vitro. The effects of PNC-27 were assessed using light microscopy, MTT assays for cell growth inhibition, and LDH assays for cytotoxicity.

Results: PNC-27 inhibited growth and was cytotoxic to primary ovarian cancer cells in a dose-dependent manner. The control peptide PNC-29 showed no effect. PNC-27 was also effective against chemotherapy-resistant cancer cell lines.

Conclusions: PNC-27 demonstrates significant efficacy against freshly isolated and chemotherapy-resistant ovarian cancer cells, suggesting its potential as an alternative treatment for resistant cancers.

Conclusion

PNC-27 represents a promising immunotherapeutic approach for cancer treatment, offering a safer alternative to traditional methods by leveraging the body's natural defenses. Its ability to selectively target cancer cells and induce membrane lysis without harming normal cells highlights its therapeutic potential. Ongoing and future research will continue to explore its applications and efficacy in various cancer types, aiming to provide effective and less toxic treatment options for cancer patients.

[govindhtech]

MSI Stealth 14 AI Studio A1V: A Hidden Powerhouse

Ready to upgrade your gaming? The MSI Stealth 14 AI Studio A1V is a gaming laptop leader in innovation and performance. Let’s explore MSI’s Stealth 14’s four outstanding characteristics, which make it the best option for gamers seeking power and adaptability.

Strong, AI-Ready The MSI Stealth 14 is a tech powerhouse as well as a gaming laptop. The AI-ready Stealth 14 is unstoppable in gaming and AI work with cutting-edge Intel Core Ultra 9 185H processors with built-in NPU and up to NVIDIA GeForce RTX 4070 graphics.

Silky Gaming The MSI Stealth 14’s butter-smooth playability is unmatched. Experience worlds with 2.8K resolution and 120Hz refresh rate gaming. Enjoy every thrill, explosion, and triumph with amazing clarity and fluidity.

Gaming and Working Anywhere You’re no longer tied to your gaming setup. Mg-AL alloy chassis makes the MSI Stealth 14 your trusted friend for gaming or working on the road. The 1.7-kg featherweight design and 72 Whr battery life let you game and work anywhere. For intensive gaming and productivity, the MSI Stealth 14 provides unmatched performance wherever.

Stable Fire Stability matters in combat. The Queen-sized Vapor Chamber Cooling on the Stealth 14 keeps your laptop cool and stable throughout prolonged gaming. No more performance drops, just continuous gameplay. Focus on the game without overheating or throttling with the MSI Stealth 14.

Design And Aesthetics Elegant and minimalist, the Stealth 14 Studio impresses. Star Blue representing a starry night sky and Pure White representing the future of technology decorate its elegant magnesium-aluminum alloy chassis. It weighs 1.7kg (3.75lbs) and is 19mm (0.75in) thin, making it easy to transition between work and pleasure anywhere.

Display A Full HD (1920×1080) IPS screen with 165Hz refresh rate or a QHD+ (2560×1440) panel with 240Hz refresh rate are available for the laptop. Gaming and creative work benefit from both alternatives’ brilliant colors, broad viewing angles, and fluid images. Multitasking and productivity benefit from the 16:10 aspect ratio’s additional vertical screen area than 16:9.

Performance The Stealth 14 Studio is powerful. Video editing, 3D rendering, and multitasking are fast with its Intel Core i9 CPUs. Even in visually intense games, the NVIDIA GeForce RTX 40 series graphics card, available in several configurations with different VRAM capacities, smoothly runs.

16GB of DDR5 RAM gives the laptop great responsiveness and lets you run numerous apps without latency. Games, apps, and data fit on the 1TB PCIe NVMe SSD.

Cooling Keeping thin and light computers running smoothly under load is difficult. With its unique vapor chamber cooling system, the Stealth 14 Studio solves this. This novel design effectively distributes CPU and GPU heat, reducing thermal throttling during intensive gaming or heavy workloads.

Connectivity Laptops include Wi-Fi 6E for high wireless rates, Bluetooth 5.3 for peripherals, and USB-A, USB-C (Thunderbolt 4), HDMI, and an SD card reader. This makes connecting external screens, storage devices, and accessories easy.

Keyboard/Trackpad Chiclet-style keyboards with per-key RGB illumination make typing pleasant and customizable on the Stealth 14 Studio. The big multi-touch trackpad offers responsive navigation.

MSI Stealth 14 Battery Life Stealth 14 Studio’s battery life is adequate for moderate usage, but not great. A single charge lasts 4-5 hours for daily chores and somewhat less for vigorous gaming. However, use and settings affect battery life.

Conclusion Gamers and creative workers seeking mobility, power, and elegance might choose the MSI Stealth 14 Studio. Its elegant appearance, strong hardware, smooth display, and efficient cooling system make it a versatile laptop that can tackle demanding jobs. While the battery life isn’t great for unplugged usage, its portability and performance make it a formidable thin and light gaming laptop candidate.

Gaming dominance and the AI-powered future await you with the Stealth 14. MSI’s Stealth 14 redefines tiny gaming laptops with its high performance, stylish appearance, and novel features. Ready to maximize your gaming? Epic gameplay awaits you with the Stealth 14.

Read more on Govindhtech.com

[nutrarespiro]

How Nasal Spray Helps To Dry Up Runny Nose

How Nasal Spray Helps To Dry Up Runny Nose – Watery nose has become a common problem for everyone. Especially in winter. Sometimes, it causes breathing problems too. People use various methods to get rid of the cold. In this modern era, Nasal Spray is becoming the prominent way of treating runny and blocked noses. Are you looking for information regarding How Nasal Spray Helps To Dry Up Runny Nose? Then, here you go!

Nasal Spray | An Overview

The nasal spray is a common and easy way to heal a runny nose. It is the best way to say no to injections and drugs. The nasal spray gives instant relief from a watery nose via spraying in the nostrils. Usually, there are two types of nasal sprays that are available in the market – Pressured canisters and bottle pumps. Moreover, other nasal sprays are introduced in the markets by authorities. That used to cure various diseases. Such as Parkinson’s disease, migraine, osteoporosis, and others. There are various pros of nasal sprays that are described below.

Merits Of Nasal Spray

1. Nasal spray aid to relieve allergic rhinitis.

2. Also, nasal spray prevents vomiting and gastric stasis. Along with this, it is the best way to reduce the pain of severe migraines.

3. Nasal sprays are known for their durability. You can use nasal sprays for 1 to 3 years.

4. Doctors can use a nasal spray for hormone replacement therapy.

5. The most advantageous perk of the nasal spray is that they have very few side effects. And, basically, safe for offspring.

What Types Of Nasal Spray Available In the Market?

There is a broad range of nasal sprays price that are available in the market at the present movement. Along with this, prices are the important factor that affects the individual choices of nasal spray. Here is the list of nasal sprays and their prices available at Nutra Respiro.

Xylometazoline Hydrochloride Nasal Solution IP 0.1% – 10ml – Rs. 48.2

Fluticasone Furoate Nasal Spray – 27.5 ml – Rs. 330

Sodium Chloride 0.65 w v Saline Nasal Spray – 50ml – Rs. 240

Azelastine Hydrochloride and Fluticasone Furoate Nasal Spray – 10ml – Rs. 425

Mometasone Nasal Spray – 10ml – Rs. 290

Oxymetazoline Hydrochloride Nasal Solution 0.25 mg – 10 ml  – Rs. 80

Thus, you know about the types and prices of nasal sprays. Let’s move to our point about how Nasal Spray Helps To Dry Up Runny Nose!

How Nasal Spray Helps To Dry Up Runny Nose

When we talk about the nasal cavity, there is no connection with the respiratory tract. According to the definition, our nasal cavity is the main part of our nose. Its main work is to keep our noses humid and warm. The nasal spectrum is another part of the nasal cavity which divides the cavity into two called fossae. The nasal activity helps smell. It also plays a key role in keeping our blood flow to the brain in control.

Smelling the nasal spray aids in preventing the risk of cold and flu. Along with it, the blood vessels help to increase the ability to captivate the steroid and give instant relief to the nose. Additionally, it helps to reduce inflammation. This is the main principle behind the working of every nasal spray.

The Leading Nasal Spray Franchise Company In India | Nutra Respiro

Nutra Respiro is the best firm in terms of manufacturing premium quality nasal sprays. If you are looking to invest in a nasal spray franchise company in India. Then, it is a golden chance for you. Besides this, it is estimated that the market of respiratory products is currently standing at US $ 1,005.50 Million, and is forecasted to increase by US $ 2,077.79 Million at the end of the decade. Apart from this, due to the Covid-19 Pandemic, the demand for respiratory products escalates among the common people. Hence, it is a profitable step towards making a career in the pharmaceutical business in India.

Conclusion

In the end, we can say that  Nasal spray is an important thing in the household. We hope that you learn about How Nasal Spray Helps To Dry Up Runny Nose. For more information, reach out to us at Nutra Respiro for the best nasal spray business opportunity in India!

[breezeinmonochromenight]

What are some of your hottest/most controversial takes regarding video games?

Uhhh like recent games or in general?

Anyway:

I think it’s really hypocritical to praise modern games like RE Village for being shorter and letting the mediocre shooting mechanics/story slide because of how gorgeous it looks when we were practically crucifying on The Order 1886 for doing this exact same thing on last gen consoles.

That being said, there is also such thing as “too much game”. It gets to a point where I just don’t care anymore. There’s a reason RDR2 sits largely untouched in my library.

The difficulty of SoulsBorne/Sekiro is so overhyped it’s embarrassing. They’re excellent games, but they’re completely doable, even if you’re new to video games entirely.

Little Hope’s ending is one of the rare few times the “none of this is real” plot twist actually worked well. Peace of mind/a better mental state/the ability to finally move on from tragedy is a worthwhile outcome even without the presence of a physical threat.

Peace Walker is better than MGSV and the best game in the series. MGS4 is still good, but the weakest entry in the series.

Raiden (MGS) didn’t need a badass cyborg ninja makeover to be interesting — he was already interesting in MGS2.

Death Stranding didn’t need to be a Metal Gear Clone, it’s fine as it is.

Devs in companies like Square Enix don’t owe anyone a faithful remake with FFVII and can do whatever the fuck they want with their IP and bitching about it does nothing. Changing things in a remake of a “classic” game/story isn’t inherently bad — it’s what you do with those changes that matters. Anyone who gets mad about that needs friends and/or a new hobby.

ACIII and AC Unity both have interesting protagonists and Unity in particular had a very interesting plot/was gorgeous to look at, but my god the fucking bugs make them miserable experiences.

While we’re on the topic of AC, Syndicate is extremely underrated and ACII + Brotherhood would have been a 10/10 and 9/10 respectively if you didn’t have to get out of the animus. I don’t care about what’s happening outside of the animus. I will never care.

Fallout 4 isn’t that fun/feels empty/doesn’t look good without mods, but it shouldn’t be the responsibility of modders to make a game fun/make it feel less empty/look better.

Abby from TLOU2 isn’t inherently a bad character at all, she just had the misfortune of being in a game with a half-assed story that’s made infinitely worse by some of the most bizarre pacing I have ever seen in a game.

I don’t think Detroit: Become Human is a bad concept for a game, but I do think it was laughably bad in execution. Connor and Hank have the best storyline and I feel like that was a total accident. David Cage is a fucking joke and absolutely shouldn’t be allowed to write these scripts, let alone without a team of heavy handed editors.

FFXV/XIII/X-2 were good, some of ya’ll are just snobs.

FFX Tidus isn’t the worst character ever, but I feel like he was put into a unique position for a protagonist and the writers failed to capitalize on it.

Faceless and/or silent protagonists are rarely ever fun, save for like the new Doom Marine. (I will never care about Ethan Winters.)

Don’t like something? Don’t waste your time on it. There’s also a big difference between criticism of something you don’t like/didn’t enjoy and endlessly pissing and moaning about how much you hate something.

[loadingra903]

Canon Service Tool V5103 Crack

When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures.

Canon service tool v1050 free download - Canon Service Tool for PJ, Canon Print Service, Canon Print Service Plugin, and many more programs. Direct download link (Windows) canon service tool v5103 free download latest tool available on internet, it's working and have a lot of built in safety tools.

When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. Hi sir, can u give me downlink of Canon Service Tool V5103. Really need it for my printer mg3620., 09:12 #4 Generatorss.

This Service tool v4905 support for G1000, IP2770, IX6560, MP258, MG6170 printer also for G Series, IX Series, IP Series, MG Series, MP Series, MX Series, and PRO Series. Click links below to download for free.

Download Service Tool v4905 (password : errorandreset.com) or link 2

Canon Service Tool V5103 Crack Download

This software cannot be used for Canon E series and MG24xx series printers. You can download Service Tool v4720 for E series Canon printers.

Service tool v4905 Support OS:

Download Canon Service Tool V5103

Windows XP

Windows Vista

Windows 7

Windows 8

Windows 8.1

Windows 10

Before using this software, make sure your Canon printer can enter into “service mode”, each printer has a different way to get into “service mode”. In general, here’s how to enter service mode on a Canon printer.

Canon Service Tool Download Free

Turn off the Canon printer, don’t unplugging the power cable.

Press and hold Resume button then press the Power button.

Keep pressing the Power button and release the Resume button.

Then press the 5x Resume button.

Then release all the Power & Resume buttons.

The power LED will blink and you’re in Service Mode and your printer ready to reset.

[recordtank4]

The Several Advantages Of Peptides.

What Are The Types Of Sarms, What Are Sarms Uk.

Content

Peptide Modifications.

Brand-new Products.

Types Of Ipeds.

Never-ceasing Science The Reaping Machine 120 Caps (ostarine).

So, How Can I Obtain Sufficient Collagen?

View your outcomes with doctor's advice, monitor any type of modifications with time as well as see the renovations you can make to your health and wellness with easy way of living adjustments. A great way to improve your performance and also get outcomes is to understand what's going on inside your body. Look past just the expense of SARMs to determine what you are mosting likely to make use of.

Products have a light-weight appearance and also a high percentage of active components, so they're a terrific way to obtain a dose of peptides, attempt Radical Skincare Advanced Peptide Antioxidant Lotion.

A copper peptide is a peptide, combined with a trace amount of copper, which, when related to skin can aid to enhance the recovery procedure by supplying copper where it's needed to regenerate broken skin.

https://pharmalabglobal.com/product-category/hcg/ up for our newsletter to receive exclusive deals and also professional skin care advice, plus get ₤ 5 off your following order.

A fine example is copper-- a normally happening mineral within our body that assists to bind collagen and also elastin with each other.

Our client treatment group are skin care and item specialists and can direct you to the most effective skin of your life.

Although the companies included speak about a market worth $1bn, to accomplish anything near to this worth any item would certainly need to show amazing effectiveness as well as it seems most likely a variety of smaller sized products will certainly arise. Offered previous scientific experience it does seem most likely that progress in this complicated illness will certainly be step-by-step. Taking a different method is PsiOxus with MT-102, an anabolic catabolic changing representative. Patients are presently being hired for a dual blind, placebo controlled stage II research study in 132 clients, with either colon or non-small cell lung cancer. Information on endpoints including a six minute strolling examination and staircase climb should be offered next year; if favorable the company will certainly seek a companion. In the meantime, data need to emerge from the mid-stage pipeline, possibly from Acacia's APD209 prior to the end of the year.

Peptide Adjustments.

The item is a combination of 2 repurposed medications-- a beta 2 adrenoreceptor agonist and a progestogen agonist. Most cachexia research is being conducted in cancer patients however any kind of effective medicine would also likely be utilized in conditions such as renal illness and persistent obstructive lung illness, where individuals regularly suffer from losing. More comprehensive possibility also depends on related conditions such as sarcopenia, muscle wasting in the elderly that is thought to impact a quarter of men over the age of 60. Cachexia is mostly connected with cancer cells; prices vary with tumor types and the phase of the disease. For example, while around 80% of pancreatic cancer cells patients are likely to deal with wasting it is no place near as usual in less aggressive tumor types.

Hold out for a great product so you can get truth value it needs to deliver. All products detailed as well as provided through SteroidsUK are planned for research purposes just. Products provided by SteroidsUK are not planned for usage in food or as any kind of sort of medicine.

New Items.

A large dosage may be absorbed one go and infusing can result in serious infection, particularly hepatitis and HIV if infusing devices is shared so tidy devices ought to constantly be utilized. Troubles such as sleep disorders, confusion, anxiety as well as paranoia might additionally be experienced.

They are cheap as well as quickly available to subdue testosterone production. Research made it known that many individuals use the SARMs in the dose range between 10 mg and 25mg. Touchdown on this page means you might need to know a few aspects of pure SARMs. We would favor a remedy to your search and also reward you with outstanding top three pure SARMs for bodybuilding. There's no big key that the SARMs can function properly to boost body language.

Kinds Of Ipeds.

Information that GTx will begin 2 stage III researches with its novel muscular tissue throwing away therapy, Ostarine, is encouraging progression for cachexia research. The condition affects a big percentage of cancer cells clients along with patients with lung as well as kidney illness, brings a significant death risk and can badly crimp lifestyle, but has few reliable treatments.

Authorities are responding very quickly and also catching defrauders offering fake SARMs. Manufacturers need to examine each product in independent labs, which should give their consent for sporting activities supplements to show up on the marketplace. Without it, customers might doubt the accuracy and also safety and security of the product as well as not buy it. Some SARMs had actually been examined years prior to they were authorized for usage. Although costliness is a loved one term, many users will certainly concur that the rates of SARMs are high.

Our items are not planned to treat, protect against, alleviate or heal any type of condition or medical condition as well as are for research study functions just. Raising understanding of the health and wellness results of PEIDs is a key focus of ASADA Chief Executive Officer David Sharpe. One recent term paper found that youngsters given synthetic human growth hormone are at substantially greater danger of creating cancer in the long-term. Various other research performed on hormonal agent peptides has actually revealed users go to raised risk of hypertensive episodes, haemorrhage, water intoxication and also even fatality.

Never-ceasing Scientific Research The Reaper 120 Caps (ostarine).

Collect information, read testimonials from various other customers, as well as figure out what the worth is from each item. A badly made product isn't going to give you the results you are after.

What are antimicrobial proteins?

Abstract. Production of antimicrobial peptides and proteins is an important means of host defense in eukaryotes. The larger antimicrobial proteins, containing more than 100 amino acids, are often lytic enzymes, nutrient-binding proteins or contain sites that target specific microbial macromolecules.

Ibutamoren or MK 677 has actually been shown to increase IGF-1 levels by 60% in 6 weeks. It is a non-hormonal and also therefore needs no PCT after the cycle is over. It will radiate more-so if ran in conjunction with SARMS S-4 and also Cardarine (GW ). This would be similar to a SARMS triple pile that is usually ran with Ostarine, except there is a possibility of more size being placed on while reducing. To conclude, the pure SARMs are not restricted to the ones stated over, but the ones provided are the leading 3 pure SURMs for muscle building. To comprehend even more regarding other health problems and its services, check our system for even more interesting information. Ostrarine is one of the best-knownproducts that are widely utilized in this century.

Besides, each type of SARMs has its method of usage as well as a number of procedures to increase performance. You either dose once or twice daily to execute its feature to contentment as well as integrity. If you disable this cookie, we will certainly not have the ability to save your choices. This means that whenever you visit this site you will require to allow or disable cookies once again. Purely Needed Cookie must be enabled whatsoever times to make sure that we can save your choices for cookie setups. It suggests that buyers have appropriate defense when purchasing sporting activities supplements, both online and offline.

Popular brand names warrant it with boosted demand for these prep work and the greater rates of resources as well as job. Yet, 99% Purity Oxytocin reviews to on-line shopping is, a lot of fraudulences happen on the web. If you do not want to be scammed, ensure that on the internet sale is lawful in your nation. Lastly, seek previous users as well as check their experiences with a specific supplier and items. The safest way to acquire something is when you can check the item right away. When it involves SARMs, one requires to understand what to examine, such as seals or how the print on the tag was done. They ought to be well informed regarding items, brands, as well as everything else that interests them prior to getting.

For a few of the most effective medications, the examinations were also pricey to conduct at amateur level. Readus's wish to go quicker was at the origin of his use of medicines, as well as a large component of the benefit was emotional. Staite was too old to transform specialist, and also despite having the medications he was a nation mile off the very best in the sport. Despite exactly how far from centrally manage Shop Ipamorelin Online - pharmalabglobal are, though, professional athletes who dope often seem to intend to make a step up to the next degree of rate and also competitors, whatever it may be. Picture they coincide type of medications that reproached biker Lance Armstrong was outlawed for using to win 7 Tour de France titles. Currently imagine that several of the fastest riders in this pleasant neighborhood competition have used medications to improve their efficiency. The British Military takes a zero-tolerance method to substance abuse.

Peptides: What are they, uses, and side effects - Medical News Today

Peptides: What are they, uses, and side effects.

Posted: Wed, 16 Oct 2019 07:00:00 GMT [source]

Readus found that a great deal of the advice regarding dosages and discovery he got was wrong, implying some professional athletes fell short drugs tests regardless of all their efforts. For endurance athletes, the medications that were preferred one decade earlier are still the ones that are prominent today. Eventually EPO is merely perfectly fit to improving performance. Olympic cyclist and also former doper David Millar determined the similar sensation-- vitamin injection became his entrance to drugs.

There are many reasons you should use only real SARMs products. Really usually, the checklist of active ingredients found in these imitations is incorrect. A survey by PHI at Liverpool John Moores College-- Steroids and Picture Enhancing Drugs 2013 Survey Outcomes-- provides comprehensive info on the level and qualities of using these drugs in the UK.

How many types of peptides are there?

There are five different types of peptides used as skin-care actives: signaling peptides, carrier peptides, enzyme-inhibiting peptides, neurotransmitter-inhibiting peptides and antimicrobial peptides. When skin is injured, proteases break down damaged tissue into different peptide fragments.

Mechano growth element which is derived from IGF-1 as well as assists with tissue repair service as well as adjustment. Development hormonal agents like AOD-9604, which has weight loss homes and is used by professional athletes to raise power-to-weight proportions. Efficiency and image enhancing medicines are taken by individuals who desire to boost their physical appearance and/or improve their toughness and showing off performance. Essentially UKAD acts upon tip-offs, similar to law enforcement, with online forums and sites marketing medications a primary source for finding prospective culprits. Don't be fooled right into believing whatever you review online is true, though.

Medications influence the fitness and integrity of service individuals and have a destructive result on operational effectiveness. Fail a drugs examination, as well as you can anticipate to be released from the service. Experts such as physio therapists suggest people on just how to reinforce muscles after an injury or operation. They will evaluate the patient as well as deal recommendations and instruct them in exercises that can be made use of to strengthen certain muscle mass teams. Muscle mass are affixed to bones so solid muscle mass can support joints and also various other parts of the skeletal system. For people that want to build the strength of their muscles for fitness gains, they might speak with an individual instructor who can tailor a workout programme to the specific with goals to safely work in the direction of.

[johnnut28]

Cyclic Peptides In Biological

What Are The Types Of Sarms, What Are Sarms Uk.

Content

Peptide Adjustments.

New Items.

Types Of Ipeds.

Never-ceasing Scientific Research The Reaping Machine 120 Caps (ostarine).

So, Just How Can I Get Enough Collagen?

View your results with medical professional's recommendations, keep an eye on any kind of changes with time and also see the renovations you can make to your health with easy way of living changes. A terrific means to improve your efficiency as well as get outcomes is to recognize what's taking place inside your body. Look beyond just the price of SARMs to decide what you are mosting likely to utilize.

Lotions have a light-weight structure and a high portion of active ingredients, so they're a wonderful way to obtain a dosage of peptides, attempt Radical Skincare Advanced Peptide Antioxidant Lotion.

Extensive scientific study has proven that peptides can sustain your skin on numerous levels, for instance firming, relaxing as well as moistening the skin.

A copper peptide is a peptide, combined with a trace quantity of copper, which, when applied to skin can help to boost the healing procedure by providing copper where it's required to regrow broken skin.

Enroll in our newsletter to receive exclusive offers as well as professional skincare advice, plus get ₤ 5 off your next order.

A fine example is copper-- a naturally occurring mineral within our body that assists to bind collagen and also elastin with each other.

Our customer treatment team are skincare as well as product professionals and can guide you to the very best skin of your life.

Although the companies involved discuss a market worth $1bn, to achieve anything close to this value any product would certainly need to reveal exceptional efficacy and also it seems more probable a number of smaller sized products will certainly emerge. Given previous scientific experience it does appear more probable that development in this complicated illness will certainly be incremental. Taking a different approach is PsiOxus with MT-102, an anabolic catabolic changing agent. Patients are presently being hired for a double blind, sugar pill regulated stage II study in 132 individuals, with either intestines or non-small cell lung cancer cells. Information on endpoints including a six min walking test as well as stair climb must be offered next year; if positive the firm will look for a companion. In the meantime, data must emerge from the mid-stage pipeline, possibly from Acacia's APD209 before the end of the year.

Peptide Adjustments.

The item is a combination of two repurposed medications-- a beta 2 adrenoreceptor agonist and a progestogen agonist. The majority of cachexia study is being carried out in cancer clients but any type of effective medicine would also likely be used in problems such as kidney disease and chronic obstructive lung illness, where individuals regularly experience squandering. More comprehensive capacity also hinges on related conditions such as sarcopenia, muscular tissue throwing away in the elderly that is thought to affect a quarter of guys over the age of 60. Cachexia is mostly associated with cancer; rates differ with tumour types and the phase of the disease. For example, while around 80% of pancreatic cancer people are likely to suffer from losing it is no place near as typical in less aggressive tumour kinds.

Claim a fantastic product so you can get truth worth it needs to supply. All products detailed as well as provided via SteroidsUK are intended for research study purposes only. Products offered by SteroidsUK are not intended for usage in foodstuff or as any kind of medication.

New Items.

A big dose may be taken in one go as well as injecting can bring about major infection, specifically liver disease as well as HIV if injecting tools is shared so clean tools must always be made use of. Troubles such as rest conditions, complication, clinical depression and paranoia may additionally be experienced.

They are affordable and also conveniently accessible to suppress testosterone production. Study made it known that lots of people use the SARMs in the dosage variety in between 10 mg as well as 25mg. Landing on this page implies you may want to know a couple of aspects of pure SARMs. We would certainly choose a remedy to your search as well as reward you with outstanding top three pure SARMs for body building. There's no huge trick that the SARMs can function correctly to enhance body movement.

Types Of Ipeds.

Information that GTx will begin two phase III researches with its unique muscle wasting therapy, Ostarine, is motivating development for cachexia research. The problem afflicts a large proportion of cancer individuals as well as clients with lung as well as kidney illness, brings a substantial death risk as well as can drastically kink lifestyle, however has couple of reliable therapies.

Authorities are reacting extremely quickly and also catching scammers offering fake SARMs. Producers need to check each product in independent research laboratories, which need to give their consent for sporting activities supplements to appear on the marketplace. Without bring your BPC157 Spain to the future , customers may doubt the accuracy as well as security of the item and also deny it. Some SARMs had been evaluated years prior to they were authorized for usage. Although costliness is a loved one term, the majority of users will agree that the prices of SARMs are high.

Our products are not intended to treat, avoid, alleviate or cure any illness or medical condition and also are for research functions only. Raising awareness of the wellness results of PEIDs is an essential emphasis of ASADA Chief Executive Officer David Sharpe. One recent research paper located that youngsters given synthetic human development hormone go to substantially greater risk of developing cancer cells in the long term. Various other research study carried out on hormonal agent peptides has actually shown customers go to increased risk of hypertensive episodes, haemorrhage, water drunkenness as well as even fatality.

Immortal Scientific Research The Reaping Machine 120 Caps (ostarine).

Collect details, reviewed evaluations from other individuals, and also learn what the value is from each product. A badly made product isn't mosting likely to give you the results you desire.

What are antimicrobial proteins?

Abstract. Production of antimicrobial peptides and proteins is an important means of host defense in eukaryotes. The larger antimicrobial proteins, containing more than 100 amino acids, are often lytic enzymes, nutrient-binding proteins or contain sites that target specific microbial macromolecules.

Ibutamoren or MK 677 has been shown to raise IGF-1 levels by 60% in 6 weeks. It is a non-hormonal as well as consequently requires no PCT after the cycle is over. It will shine more-so if ran in conjunction with SARMS S-4 and also Cardarine (GW ). This would be similar to a SARMS three-way pile that is normally kept up Ostarine, except there is an opportunity of even more size being put on while cutting. To conclude, the pure SARMs are not restricted to the ones mentioned above, however the ones noted are the top 3 pure SURMs for muscle building. To understand more about various other health problems and its solutions, examine our platform for even more fascinating details. Ostrarine is just one of the best-knownproducts that are extensively used in this century.

So, Just How Can I Obtain Sufficient Collagen?

Besides, each kind of SARMs has its approach of usage and also numerous protocols to enhance productivity. You either dosage once or twice each day to execute its feature to contentment as well as integrity. If you disable this cookie, we will not have the ability to save your choices. This implies that every single time you see this website you will certainly need to allow or disable cookies again. Purely Needed Cookie ought to be made it possible for at all times to ensure that we can save your preferences for cookie setups. It means that buyers have correct security when purchasing sporting activities supplements, both online and offline.

Protein that can be toxic in the heart and nerves may help prevent Alzheimer's - EurekAlert

Protein that can be toxic in the heart and nerves may help prevent Alzheimer's.

Posted: Thu, 07 Jan 2021 16:45:52 GMT [source]

Popular brand names justify it with raised demand for these preparations as well as the higher rates of raw materials and also job. Yet, comparable to on the internet shopping is, many fraudulences occur online. If you do not wish to be scammed, make certain that online sale is lawful in your nation. Lastly, seek previous users and also examine their experiences with a particular supplier and items. The most safe way to get something is when you can inspect the item right away. When it comes to SARMs, one needs to recognize what to check, such as seals or how the print on the label was done. They ought to be well notified regarding products, brand names, as well as whatever else that interests them prior to buying.

For a few of one of the most powerful medications, the examinations were also pricey to perform at amateur level. Readus's wish to go quicker was at the root of his use of medications, and also a big part of the advantage was mental. Staite was as well old to transform specialist, and also even with the medicines he was a nation mile off the best in the sport. Despite how far from the elite they are, however, athletes who dope frequently appear to wish to make a step up to the next degree of speed as well as competitors, whatever it might be. Envision they're the same sort of medications that shamed bicyclist Lance Armstrong was banned for utilizing to win 7 Tour de France titles. Now imagine that a few of the fastest motorcyclists in this pleasant local competitors have actually utilized medicines to boost their efficiency. The British Army takes a zero-tolerance approach to compound misuse.

information BPC157 Canada ='border: black solid 1px;padding: 12px;'>

Peptides: What are they, uses, and side effects - Medical News Today

Peptides: What are they, uses, and side effects.

Posted: Wed, 16 Oct 2019 07:00:00 GMT [source]

Readus located that a lot of the recommendations about dosages as well as discovery he got was inaccurate, meaning some athletes failed medications tests despite all their efforts. For endurance athletes, the medications that were preferred 10 years earlier are still the ones that are preferred today. Ultimately EPO is just completely matched to boosting efficiency. Olympic biker as well as former doper David Millar identified the very same phenomenon-- vitamin injection became his entrance to medications.

There are lots of reasons why you ought to make use of just authentic SARMs items. Really frequently, the list of active ingredients found in these fakes is false. A study by PHI at Liverpool John Moores University-- Steroids and Picture Enhancing Medicines 2013 Survey Outcomes-- gives thorough information on the degree and attributes of making use of these drugs in the UK.

How many types of peptides are there?

There are five different types of peptides used as skin-care actives: signaling peptides, carrier peptides, enzyme-inhibiting peptides, neurotransmitter-inhibiting peptides and antimicrobial peptides. When skin is injured, proteases break down damaged tissue into different peptide fragments.

Mechano growth variable which is stemmed from IGF-1 as well as helps with tissue fixing and adaptation. Development hormones like AOD-9604, which has fat burning buildings as well as is utilized by professional athletes to boost power-to-weight ratios. Performance as well as image enhancing medications are taken by people who desire to improve their physical appearance and/or enhance their toughness and also showing off efficiency. Basically UKAD acts on tip-offs, just like police, with discussion forums and websites selling medications a main source for finding prospective culprits. Do not be fooled into thinking everything you review online is true, though.

Medications impact the fitness as well as dependability of service individuals as well as have a harsh effect on operational performance. Fail a medications examination, as well as you can anticipate to be discharged from the solution. Professionals such as physiotherapists suggest people on how to enhance muscles after an injury or procedure. They will assess the client and offer recommendations as well as instruct them in workouts that can be used to reinforce particular muscle mass teams. Muscle mass are attached to bones so strong muscles can sustain joints and various other components of the skeletal system. For individuals who wish to build the stamina of their muscular tissues for health and fitness gains, they might consult an individual trainer that can customize an exercise program to the private with objectives to safely function towards.

[skulkngs83]

Fan Art Friday (10-04-2019)

I guess I’m more a fan of Shinkawa Yoji than MGS itself as an IP. For this study of Olga Gurlukovich from MGS 2, I used a red bic pen for the underdrawing, then a red pilot pen to bring out some of the line, then a red brush tip pen for the thicker lines. Unfortunately tho the red pens were all different shades, and on top of that the ink from the brush tip pen was more transparent. If you look close you can see how some lines are darker than others...oh well... I actually didn’t want to do another study, but I ran out of time to do an “original”, so sorry tumblr, this is all you get this week. Hopefully next week I’ll manage my time better and do something original...we’ll see...

after Shinkawa Yoji

Olga Gurlukovich and Metal Gear Solid are (c) of Konami

[literaticat]

What percentage of middle grade novels would you estimate go out on submission and get zero bites?

... uhh I'm no math wizard but this feels like a pretty effed up algebraic type deal. I couldn’t begin to estimate how many middle grade manuscripts there ARE in the world at any given time? Does an average agent have 1 MG out, or 5, or 20? or More??? How many editors per book? How many of those are targeted correctly? How many are with schmagents? How many are GREAT versus Just OK? Does a “bite” mean “an offer of publication” or could a “bite” be interpreted as “some other expression of interest, such as an R&R, or an offer to do an IP book?” There’s just a lot of unknown variables here?

Like -- I have a spreadsheet of things I’ve actually SOLD. I’ve sold 10 MG novels in the past year. I’ve gone out with more like, 16? But.... There are a few things that are still on submission, that haven’t sold YET, but I have no reason to think won’t. There are a couple of things that I sent out and didn’t get an offer, and the author is revising or whatever -- but maybe they will in the future when we do another round. So... I mean... ???? Maybe 20% ??? For ME? But my sell-through rate might be different than another agents so...

[yulliu]

全民福利

qq号 证件号 可以查出来ip地址或者家庭住址的兄弟

前10位 可以直接去她家 享受女仆服务

有技术的可以私我

会给你一个测试的qq或者证件号 说对了给mg的

[breezeinmonochromenight]

My apologies for bothering. I have some questions please. With the Metal Gear Solid movie coming out sometime in the distant future, do you have any fears or concerns about the movie? Are there any specific scenes from the games that come to mind that you’d like to see in the movie? Any scenes you wouldn’t like to see? Any actors you have in mind you’d like to see in the movie? Any actors you think wouldn’t fit in a Metal Gear Solid movie? Many, many thanks :)

You’re never a bother, Anon! And I love Metal Gear questions anyway. (:

To be brutally honest, I have far, far more concerns versus positive thoughts about a Metal Gear Solid movie. I’ve seen both of Konami’s previous attempts at game to make Silent Hill into a movie franchise and neither of them are good.

(Without rambling on endlessly in an essay, I’ll try to just bullet things to answer your questions specifically lol.)

Let me start with the obvious/the general concerns:

Basically everything in my being is screaming that this is a terrible, no good, very bad idea.

Game-to-movie adaptations are, more often than not, terrible. Some story aspects and tones are conveyed best through game mechanics, and that does not tend to translate well to a non-interactive movie. This is especially true in this franchise.

Konami is still Konami, and Konami is the worst.

No really. Fuck Konami. Metal Gear Survive is a thing that exists in this world, and is proof they can fuck up having even when having what is essentially the IP equivalent of an infinite money cheat in their hands. They invented the Konami code ffs and they’re still fucking things up, in a sense. I do not trust them not to meddle.

Seriously, this all sounds like another cash grab, just like Metal Gear Survive. Konami should have found a new game director to head a Metal Gear/Metal Gear Rising 2 or something and have him consult Kojima like the movie director is currently doing. That would have been the wisest thing to do. The absolute best decision Konami could have done, post-Kojima — for the franchise and to save face — would have been to hit up Platinum Games again and get MGRR2 in the works. That would be largely hands off — just like a movie — and people really wanted that.

Please GOD just stick to one game — like Metal Gear Solid 1. PLEASE. The story of MGS as a whole is incredible, but an absolute fucking mess to try and sort out — the games themselves have literal hours of cutscenes without any of the action/playable sections. Trying to cram upwards of 6 games + action/stealth scenes into a ~2 hour movie asking for a disaster. This is what exactly happened with Silent Hill.

While graphics became outdated, Kojima’s shot compositions and the way his cutscenes are set up did not. I’m hoping the director sticks to them and doesn’t try to ‘leave his mark’ on the series or ‘make it his own’.

Real talk: MGS3 Snake Eater would have probably made the best movie.

Scenes I want/don’t want to see:

I’m not super picky, but in general — please don’t keep the exposition dumps. It works in the games because I know I’m going to be in control again soon, and it gives me something meaty to chew on while I work through objectives. It doesn’t work in a movie. In terms of MGS1, for example, I personally would not be able to sit through Otacon monologuing for nearly 10 fucking minutes after he’s just pissed his pants only to sit through more movie — especially when it’s going to be an actor that doesn’t sound like Christopher Randolph and may/may not even look like the Hal I know and love. The monologues on Game of Thrones are fucking annoying at best and part of the reason I threw in the towel on that series — I couldn’t imagine how much worse MGS ones would be.

Either go full Metal Gear/Kojima weird or don’t. Don’t half-ass it. Peferably do go full Kojima-brand weird and do some 4th wall breaking. Have fun with it. Actually have a codec call screen or something. Don’t try to turn it into a serious and dramatic action/espionage Hollywood blockbuster.

Remember that, despite their look and subject matter, they’re distinctly anti-war games. Do not try to take that out of them/the scenes and conversations that underline this out to appeal to western/American audiences.

Actors I do/don’t want to see:

Is David Hayter available? If not for the acting, can we just dub his voice over the actor? Please?

Barring the real Solid Snake, I’ve seen Scott Eastwood, Oscar Isaac, Tom Hardy, and Christian Bale’s names thrown around the most. Personally, Oscar Isaac has grown on me the most, and I think the mock poster (below) that’s been floating around the internet/reddit really sold it for me. Not totally convinced but he’s looking like the best choice. He’s a good actor, but he’s also got a strikingly similar nose/brow/jawline to Solid Snake. I feel like you could convincingly pass him off as a younger/MGS1 era Snake with little to no effort.

If for some reason Big Boss is the focus, then I’d say just get Kiefer Sutherland or something. They used some of his features on VB anyway, it wouldn’t be the worst thing in the world.

Please, god, anyone except Chris Evans lol.

[criticinecare]

Select the Right Company for Critical Care Franchise in India

Select the Right Company for Critical Care Franchise in India – Starting your own business in the pharma sector is a big hassle. But it can be sorted out by Selecting the Right Company for Critical Care Franchise in India. If you want to start your own injectable range business and want to get the best business deals without having to struggle with online research, analysis, and so on. If so, then give a shot to Criticine Care. Criticine Care is the Best PCD Pharma Company in India for Injectable Range, bringing you a healthy range of Critical Care injectable range at unbelievable prices. Criticine Care offers the best Critical Care PCD Pharma Franchise deals allowing you to start your own profitable business with guaranteed returns and scalable income.

Criticine Care is an ISO-certified pharmaceutical company with GMP-WHO-approved manufacturing units, world-class infrastructure, in-house quality checks, and an exceptional team of doctors and pharma experts. The company ensures that the injections are 100% quality inspected and that they are completely transparent with their clients and customers. Working with Criticine Care, the Top PCD Pharma Company for Injectable Range in India, will give you the opportunity to obtain an amazing injectable range that is preferred by doctors and highly required in the market. So, if you want to Select the Right Company for Critical Care Franchise in India, then choose Criticine Care.

How Criticine Care is the Right Company for Critical Care Franchise in India

If you want to Select the Right Company for Critical Care Franchise in India, then choose Criticine Care. Criticine Care is one of India's most trusted and dependable pharmaceutical companies, providing a wide range of critical care injections with full quality assurance. The company is legally registered and has all of the necessary accreditations to operate freely in the Indian market. You will find a wide variety of high-quality products from us that offer good value for money. The company owns cutting-edge manufacturing facilities outfitted with modern amenities and high-tech equipment.

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Criticine Care, the Best PCD Pharma Company for Injectable Range in India, has created a result-oriented and life-saving injectable range that is a perfect synonym for quality, effectiveness, and safety. The products we offer have all been clinically tested and are supported by ground-breaking research. Our injections are created in high-tech labs by India's top doctors and pharma professionals using high-quality raw materials. Furthermore, these injections are packed in leak-proof, airtight packaging with proper labeling and branding. So, if you want to get your hands on a quality injection range, then Select the Right Company for Critical Care Franchise in India, Criticine Care.

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6. Cerebroprotein Hydrolysate 60 MG Injection

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9. L-Ornithine-L-Aspartate Infusion

10. CEFOPERAZONE 250MG & TAZOBACTAM 31.25MG FOR Injection

11. Cefoperazone 1 GM + Sulbactam 500 MG Injection

12. Clarithromycin 500MG Injection

Select the Right Company for Critical Care Franchise in India “Criticine Care”

Collaboration with the Best PCD Pharma Company for Injectable Range in India, Criticine Care, will be a great business decision if you are looking to start your own business with quality and highly demanded critical care injectable range. Criticine Care is your answer to all of your business needs, with modernistic resources, a broad injection range, quality management, a powerful logistic system, and much more.

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