#G-Protein Coupled Receptors Market Trends

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G-Protein Coupled Receptors (GPCRs) Market Growth, Trends 2024-2030

G-Protein Coupled Receptors (GPCRs) Market is expected to reach US$ 5.42 Bn. at a CAGR of 6.7% during the forecast period 2030. G-protein coupled receptors (GPCRs), also known as seven-(pass)-Trans membrane receptors, are a varied collection of membrane receptors. These are found in the cell membrane and are responsible for binding external chemicals and transmitting signals from them to an intracellular molecule.

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Navigating the Landscape of the Global G-Protein Coupled Receptors Market: Trends and Opportunities

Introduction: The global G-Protein Coupled Receptors (GPCRs) market is witnessing a paradigm shift, fueled by advances in molecular biology, structural biology, and computational modeling. As researchers uncover the intricate signaling mechanisms mediated by GPCRs, new opportunities emerge for drug discovery and therapeutic intervention. In this blog post, we explore key trends and opportunities shaping the landscape of the global GPCR market. Global G-protein coupled receptors market size is expected to reach US$ 7.86 Bn by 2031, from US$ 4.67 Bn in 2023, exhibiting a compound annual growth rate (CAGR) of 7.7% during the forecast period. Emerging Therapeutic Areas: Traditionally, G-Protein Coupled Receptors Market Demand drugs have been primarily focused on indications such as cardiovascular diseases, inflammation, and central nervous system disorders. However, recent research has identified GPCRs as key players in a broader range of therapeutic areas, including: Immuno-oncology: GPCRs expressed on immune cells modulate immune responses and tumor microenvironment, presenting new targets for cancer immunotherapy. Check more trending articles related to this topic: https://cmiinfopiece.blogspot.com/2024/03/fluid-dynamics-understanding-chemical.html

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G-Protein Coupled Receptors (GPCRs) Market Size Worth $4.36 Billion By 2026 | CAGR 6.7% | Grand View Research, Inc.

The global G-protein coupled receptors market size is expected to reach USD 4.36 billion by 2026 registering a CAGR of 6.7%, according to a new report by Grand View Research, Inc. Rising adoption of faster and accurate High-Throughput Screening (HTS) technology by pharmaceutical firms to develop potential G-protein coupled receptor-targeted therapeutics is expected to augment the market growth. HTS is used on the G-protein coupled receptor cell-based assays to assist several drug development programs.

Structural and functional features of G-protein coupled receptors (GPCRs) allow it to mediate physiological responses to hormones, stimulants, and neurotransmitters, thus making them as potential therapeutic targets for various diseases. Recent advancements in the structural biology of GPCRs have provided insights into the molecular mechanisms of these receptors’ activation and activity. Several pharmaceutical companies are undertaking efforts to develop G-protein coupled receptors-targeted therapeutics for several disorders.

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In December 2018, Boehringer Ingelheim collaborated with Domain Therapeutics to discover GPCR targets for the treatment of cancer, Central Nervous System (CNS), and immunological disorders. Moreover, in May 2019, Evotec OAI AG partnered with Euroscreen S.A. to improve its capabilities for GPCR targeting. Evotec OAI will access GPCR reagents and AequoScreenTM technology of Euroscreen for its drug discovery procedures. Such initiatives enhance the product adoption as well as drug screening expertise in the pharmaceutical industry.

North America is likely to be at the forefront of the market throughout the forecast period due to heavy investments in cancer research to address the rising demand for drug discovery and development procedures in U.S. Whereas, Asia Pacific is expected to register the fastest CAGR over the forecast years. The region witnesses a rising number of therapeutics development and contract research, thus boosting G-protein coupled receptors market growth.

Grand View Research has segmented the global G-protein coupled receptors market on the basis product, assay type, application, and region:

GPCRs Product Outlook

Cell Lines

Detection Kits

Cell Culture Reagents

Ligands

 GPCRs Assay Type Outlook

cAMP Functional Assays

Calcium Functional Assays

β-Arrestin Functional Assays

Radioligand Binding and GTPγS Functional Assays

Internalization Assays

Trafficking Assays

Other Assays

 GPCRs Application Outlook

Cancer Research

CNS Research

Metabolic Research

Cardiovascular Research

Respiratory Research

Inflammation Research

Other Application

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G-Protein Coupled Receptor (GPCR) Targeting Market 2022 Trends, Growth Opportunities, Industry Revenue and Business Analysis by Forecast – 2027

G-Protein Coupled Receptor (GPCR) Targeting Market research report covers inclusive data on prevalent trends, drivers, growth opportunities, and restraints that can variation the market changing aspects of the global industry. This report provides an in-depth analysis of the market segmentation that contains products, applications, and geographical analysis. Global G-Protein Coupled Receptor (GPCR) Targeting market report delivers a close watch on leading participants with strategic analysis, micro and macro market trend and scenarios, pricing analysis, and a complete overview of the industry conditions during the forecast period.

Report Coverage:

The research report of the defending coatings industry offers a inclusive analysis of existing companies that can affect the market outlook throughout the forthcoming years. In addition to that, it affords an accurate assessment by highlighting data on multiple aspects that may contain growth drivers, opportunities, trends, and hindrances. It also represents the overall: G-Protein Coupled Receptor (GPCR) Targeting market size from a global perception by analysing historical data and qualitative insights.

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G-Protein Coupled Receptor (GPCR) Targeting Market is envisaged to record an expansion at the CAGR of 2.6% over the forecast period, 2022 – 2027.

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Global G-protein coupled receptors (GPCRs) market is expected to register a substantial CAGR of 9.3% in the forecast period of 2019-2026. This rise in the market can be attributed to the increasing health problems such as cardiovascular diseases, advancement in technology of cryotherapy equipment and high application in research and development for newer drugs.

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Global G-Protein Coupled Receptors Market Demand, Sales and Cost Structure Analysis, Forecast to 2025

Global G-Protein Coupled Receptors Market Research Report: By Product (Cell Lines, Detection Kits, Cell Culture Reagents, Ligands), By Assay Type (Calcium Functional Assays, cAMP Functional Assays, cGMP Assays, Others) and By Application (Cardiovascular System, Oncology, Immunology, Respiratory System, Others) – Forecast to 2025

As per Market Research Future (MRFR) analysis, the global G protein coupled receptors market is expected to reach USD 3,100 million with a CAGR of 7.1% CAGR from 2017 to 2024 (forecast period). The study also analyses the impact of COVID-19 on the G-protein coupled receptor market and provides a clear assessment of the expected market fluctuations during the forecast period.

G-protein coupled receptors (GPCRs), also referred as seven-transmembrane domain receptors, 7-TM receptors, serpentine receptors, heptahelical receptors, and G-protein-linked receptors (GPLRs), are a broad family of receptor proteins that detect molecules outside the cell and enable internal signal transduction pathways and, ultimately, cellular responses. Coupled with G proteins, they are called seven-transmembrane receptors because they pass across the cell membrane seven times.

Market Dynamics

The growth of the global market for G-protein coupled receptors (GPCR) is driven by a variety of factors, such as increased use of G-protein combined receptors in drug disclosure and advancement forms, and an increase in the number of drugs in clinical and preclinical studies targeting these receptors. However, the high cost of maintaining GPCR cell lines and strict government policies is expected to reduce the global market growth for G-protein coupled receptors.

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Segmentation

The global market for G-protein coupled receptors has been segmented based on the product, assay type, and application.

Based on the product, the market has been divided into cell lines, detection kits, cell culture reagents, ligands, and others. The segment for detection kits are plausible to be the fastest during the evaluation period as they are ready to use kits that include all cells and reagents to conduct functional GPCR assay in live cells, thereby pushing the growth of the global G protein coupled receptor market.

Based on assay type, the global G-protein coupled receptor market has been segmented into functional calcium assays, cGMP assays, internalization assays, GTP gamma S binding assays, cAMP functional assays, ß-Arrestin Functional Assays, and others. Calcium functional assays are the strongest segment, with numerous advantages, such as user configurability and ease in estimating calcium flux, thereby driving this segment's growth in the GPCR market.

Based on the application, the global G protein coupled receptors market has been segmented into the cardiovascular system, oncology, respiratory system, immunology, central nervous system, and others. The cardiovascular system is a significant segment of angiotensin II, and β-adrenergic receptors provide treatment for a wide variety of cardiovascular disorders, such as heart failure. Nearly 17.9 million people die every year from cardiovascular disease, therefore increasing the G-protein coupled receptor market.

Regional Analysis

Regionally, the market for G-protein coupled receptors has been divided into the Americas, Europe, the Asia Pacific, and the Middle East & Africa.

The Americas is estimated to be the leading market due to the presence of a large number of approved drugs targeting G-protein coupled receptors. The market for G-protein coupled receptors in the Americas was further divided into North America and Latin America, with the North American market divided into the United States and Canada.

The European G-protein coupled receptor market has been classified as Western Europe and Eastern Europe. The Western European market has also been classified as Germany, France, the United Kingdom, Italy, Spain, and the rest of Western Europe.

The market for G-protein coupled receptors in the Asia Pacific has been segmented into China, Japan, South Korea, India, Australia, and the rest of the Asia Pacific. The number of approved drugs targeting GPCRs has propelled the growth of the G-protein coupled receptor market and is projected to be the fastest-growing market in the Asia Pacific. The market for G-protein coupled receptors in the Middle East and Africa has been divided into the Middle East and Africa.

Key Players

Some of the major participants in the global G protein coupled receptor market are Thermo Fisher Scientific, Inc., Cisbio, Abcam PLC, PerkinElmer Inc., Merck Group, Promega Corporation, HD Biosciences Co., Ltd, QIAGEN, Enzo Life Sciences, and Inc.BD. Many industry players currently dominate the global G-protein coupled receptors industry. The leading players are involved in product launches and strategic alliances to reinforce their market positions.

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Diabetic Nephropathy Market Forecasts Detailed in New Research Report

The increase in research and development funds for drug discovery followed by growing awareness of kidney-related disorders, and diabetes are the major factors driving the expansion of the global diabetic nephropathy market.

Globally, many programs are organized by the American Diabetes Association to prevent diabetes, create awareness among vulnerable populations, and ensure that all patients with diabetes are able to get the best care, information and treatment about diabetes management. Thus, the increased awareness about diabetic nephropathy drugs is a new trend that is expected to influence the growth of the global diabetic nephropathy market during the forecast period.

It is a disease which affects the kidney glomerulus and one of the most major issues for diabetic patients. Not only the person with diabetes has to undergo kidney impairment, but also the acute cases of diabetic nephropathy could lead to kidney miscarriage. The disease affects the kidneys in a way that makes it futile. Progressive growth in proteinuria and failure in renal function, hypertension, and high risk of cardiovascular disease are the major side effects of chronic diabetic nephropathy. Blood pressure (BP) control is necessary in minimizing the progression of diabetic nephropathy. Irrespective of the agent used, lower blood pressure in type II diabetics could slow down the start and progression of diabetic nephropathy.

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On the basis of mode of treatment, the global diabetic nephropathy market is segmented into disease modifying therapies and others. Disease modifying therapies is further categorized into diuretics, angiotensin-converting enzyme inhibitors, antioxidant inflammation modulator, angiotensin receptor blockers, renin inhibitors, calcium channel blockers, connective tissue growth factor inhibitors, monocyte chemoattractant proteins inhibitor, G protein-coupled receptors and endothelin (a receptor antagonist).

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Lack of complete therapeutic management for diabetic nephropathy, longer approval time for drugs as well as, harsh regulatory requirements are hampering the market growth of global diabetes nephropathy market.

Some of the major competitors in the global diabetic nephropathy market are Novartis AG, Merck & Co., Inc., Pfizer Inc., Abbott Laboratories, Sanofi, Eli Lilly and Company, Reata Pharmaceuticals, Inc., Bayer AG, AbbVie Inc., and Mitsubishi Tanabe Pharma Corporation.

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G-Protein Coupled Receptors (GPCRs) Market Statistical Snapshot: Unveiling Segmentation, Outlook, and Overview Trends | 2024-2030

G-protein coupled receptors (GPCRs), also known as seven-(pass)-Trans membrane receptors, are a varied collection of membrane receptors. These are found in the cell membrane and are responsible for binding external chemicals and transmitting signals from them to an intracellular molecule.

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“G-Protein Coupled Receptors Market” report provides a detailed analysis of Global Market Size, Growth Potential, Trends Analysis, Competitive Market Size and Forecast.

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G-Protein Coupled Receptor (GPCR) Targeting Market 2022 Trends, Growth Opportunities, Industry Revenue and Business Analysis by Forecast – 2027

Report Title G-Protein Coupled Receptor (GPCR) Targeting is one of the most comprehensive and important additions to the Verified Market Reports. Provides detailed research and analysis of key aspects of the global G-Protein Coupled Receptor (GPCR) Targeting market. Market analysts write in-depth information provided in this report is a complete analysis of the global G-Protein Coupled Receptor (GPCR) Targeting Market, providing leading growth drivers, restraints, challenges, trends, and opportunities. Market participants can use analysis for market dynamics to plan effective growth strategies and prepare for future challenges. Each trend of the global G-Protein Coupled Receptor (GPCR) Targeting market is carefully analysed and studied by market analysts.

G-Protein Coupled Receptor (GPCR) Targeting Market is envisaged to record an expansion at the CAGR of 2.6% over the forecast period, 2022 – 2027.

Complete report on G-Protein Coupled Receptor (GPCR) Targeting Market report spread across 150+ pages, list of tables & figures, profiling 10+ companies. Read Detailed Index of Full Research Study at @