#Fluorescence In Situ Hybridization Probe forecast

[healthcarefuture]

DNA Probe-Based Diagnostics: Key Drivers, Market Trends, and Industry Insights

DNA Probe-based Diagnostics involve the use of DNA probes—single-stranded DNA sequences designed to detect the presence of complementary nucleic acid sequences. This method is highly specific, as it targets sequences unique to pathogens or genes of interest, enabling accurate identification of diseases at a molecular level. DNA probes are invaluable in diagnosing infections, genetic disorders, and cancers. In recent years, DNA Probe-based Diagnostics have advanced significantly, enabling quicker, more sensitive, and cost-effective tests compared to traditional diagnostic approaches. The probes often detect diseases earlier than conventional methods, which allows for timely interventions and treatment.

In 2022, the market for DNA probe-based diagnostics was projected to be worth 2.81 billion US dollars. By 2032, the DNA probe-based diagnostics market is projected to have grown from 3.09 billion USD in 2023 to 7.4 billion USD. During the forecast period (2024-2032), the DNA Probe-based Diagnostics Market is anticipated to develop at a CAGR of around 10.17%.

DNA Probe-based Diagnostics Size and Share

The global DNA Probe-based Diagnostics market has experienced substantial growth, driven by advancements in biotechnology, an increase in research activities, and rising demand for personalized medicine. This market’s size continues to expand, supported by high adoption rates in hospitals, clinics, and research laboratories. As of recent estimates, the market is expected to grow at a consistent compound annual growth rate (CAGR) over the next few years. This growth is fueled by increasing government initiatives, rising investments in healthcare infrastructure, and growing awareness of the importance of early disease detection.

The market share of DNA Probe-based Diagnostics is significant in the molecular diagnostics sector, with applications across diverse fields including infectious disease diagnostics, oncology, genetic testing, and forensic sciences. North America currently holds a major share, driven by the advanced healthcare infrastructure, high investment in research and development, and a strong focus on precision medicine. However, Asia-Pacific is anticipated to see the fastest growth due to increasing healthcare expenditures, rising prevalence of chronic diseases, and a growing demand for advanced diagnostic technologies.

DNA Probe-based Diagnostics Analysis

DNA Probe-based Diagnostics utilize several analysis methods that contribute to their accuracy and reliability. Techniques such as fluorescence in situ hybridization (FISH), polymerase chain reaction (PCR), and nucleic acid amplification tests (NAATs) are commonly employed in DNA probe diagnostics. Each method has its unique advantages: FISH, for instance, allows for the visualization of DNA in chromosomes, making it particularly useful in genetic and cancer diagnostics. PCR amplifies DNA sequences to enhance detection sensitivity, while NAATs are known for their high precision in identifying pathogenic DNA in low-abundance samples.

The analysis of DNA Probe-based Diagnostics reveals trends that continue to shape the industry, including the growing shift towards digital and point-of-care diagnostics, which are particularly valuable in low-resource settings. The trend of miniaturization and automation in DNA probe diagnostics has further improved throughput, making these diagnostics faster and more accessible to a larger population.

DNA Probe-based Diagnostics Trends

Several notable trends are currently driving the growth and development of DNA Probe-based Diagnostics. The first is the increase in demand for personalized and precision medicine, where diagnostics are tailored to individual genetic profiles, providing targeted treatments. Second, there is an expansion in the use of DNA probes for infectious disease diagnostics, especially in the detection of viruses such as COVID-19, which highlighted the need for rapid, accurate diagnostics. Third, advancements in microfluidics and lab-on-chip technologies are making diagnostics more compact and accessible. Fourth, automation and digitalization are improving the accuracy and speed of diagnostic results, and fifth, next-generation sequencing (NGS) technologies are pushing the limits of what DNA probes can detect.

Reasons to Buy DNA Probe-based Diagnostics Reports

Comprehensive Market Insight: Reports provide an in-depth understanding of the DNA Probe-based Diagnostics market, covering all segments, growth factors, challenges, and opportunities.

Competitive Analysis: Detailed profiles of key market players, their strategies, and competitive positioning give buyers a clear view of the competitive landscape.

Trend Analysis: Reports analyze current and emerging trends in the diagnostics market, providing data-driven insights to make informed decisions.

Strategic Recommendations: Clear, actionable insights help stakeholders identify areas of growth and potential investment opportunities.

Recent Developments: Reports cover the latest advancements, regulatory updates, and innovations within the DNA probe diagnostics field.

Recent Developments

Recent developments in DNA Probe-based Diagnostics include the integration of artificial intelligence (AI) for faster data interpretation and the launch of more portable diagnostic devices. The shift toward at-home diagnostic kits has also gained momentum, with many new products entering the market that allow patients to conduct self-tests. Additionally, advancements in CRISPR technology are enhancing the accuracy and versatility of DNA probes, especially in gene editing applications.

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[farmacuticals]

Market Insights: Drivers and Future Scope of DNA Probe-based Diagnostics

DNA Probe-based Diagnostics involve the use of DNA probes—single-stranded DNA sequences designed to detect the presence of complementary nucleic acid sequences. This method is highly specific, as it targets sequences unique to pathogens or genes of interest, enabling accurate identification of diseases at a molecular level. DNA probes are invaluable in diagnosing infections, genetic disorders, and cancers. In recent years, DNA Probe-based Diagnostics have advanced significantly, enabling quicker, more sensitive, and cost-effective tests compared to traditional diagnostic approaches. The probes often detect diseases earlier than conventional methods, which allows for timely interventions and treatment.

In 2022, the market for DNA probe-based diagnostics was projected to be worth 2.81 billion US dollars. By 2032, the DNA probe-based diagnostics market is projected to have grown from 3.09 billion USD in 2023 to 7.4 billion USD. During the forecast period (2024-2032), the DNA Probe-based Diagnostics Market is anticipated to develop at a CAGR of around 10.17%.

DNA Probe-based Diagnostics Size and Share

The global DNA Probe-based Diagnostics market has experienced substantial growth, driven by advancements in biotechnology, an increase in research activities, and rising demand for personalized medicine. This market’s size continues to expand, supported by high adoption rates in hospitals, clinics, and research laboratories. As of recent estimates, the market is expected to grow at a consistent compound annual growth rate (CAGR) over the next few years. This growth is fueled by increasing government initiatives, rising investments in healthcare infrastructure, and growing awareness of the importance of early disease detection.

The market share of DNA Probe-based Diagnostics is significant in the molecular diagnostics sector, with applications across diverse fields including infectious disease diagnostics, oncology, genetic testing, and forensic sciences. North America currently holds a major share, driven by the advanced healthcare infrastructure, high investment in research and development, and a strong focus on precision medicine. However, Asia-Pacific is anticipated to see the fastest growth due to increasing healthcare expenditures, rising prevalence of chronic diseases, and a growing demand for advanced diagnostic technologies.

DNA Probe-based Diagnostics Analysis

DNA Probe-based Diagnostics utilize several analysis methods that contribute to their accuracy and reliability. Techniques such as fluorescence in situ hybridization (FISH), polymerase chain reaction (PCR), and nucleic acid amplification tests (NAATs) are commonly employed in DNA probe diagnostics. Each method has its unique advantages: FISH, for instance, allows for the visualization of DNA in chromosomes, making it particularly useful in genetic and cancer diagnostics. PCR amplifies DNA sequences to enhance detection sensitivity, while NAATs are known for their high precision in identifying pathogenic DNA in low-abundance samples.

The analysis of DNA Probe-based Diagnostics reveals trends that continue to shape the industry, including the growing shift towards digital and point-of-care diagnostics, which are particularly valuable in low-resource settings. The trend of miniaturization and automation in DNA probe diagnostics has further improved throughput, making these diagnostics faster and more accessible to a larger population.

DNA Probe-based Diagnostics Trends

Several notable trends are currently driving the growth and development of DNA Probe-based Diagnostics. The first is the increase in demand for personalized and precision medicine, where diagnostics are tailored to individual genetic profiles, providing targeted treatments. Second, there is an expansion in the use of DNA probes for infectious disease diagnostics, especially in the detection of viruses such as COVID-19, which highlighted the need for rapid, accurate diagnostics. Third, advancements in microfluidics and lab-on-chip technologies are making diagnostics more compact and accessible. Fourth, automation and digitalization are improving the accuracy and speed of diagnostic results, and fifth, next-generation sequencing (NGS) technologies are pushing the limits of what DNA probes can detect.

Reasons to Buy DNA Probe-based Diagnostics Reports

Comprehensive Market Insight: Reports provide an in-depth understanding of the DNA Probe-based Diagnostics market, covering all segments, growth factors, challenges, and opportunities.

Competitive Analysis: Detailed profiles of key market players, their strategies, and competitive positioning give buyers a clear view of the competitive landscape.

Trend Analysis: Reports analyze current and emerging trends in the diagnostics market, providing data-driven insights to make informed decisions.

Strategic Recommendations: Clear, actionable insights help stakeholders identify areas of growth and potential investment opportunities.

Recent Developments: Reports cover the latest advancements, regulatory updates, and innovations within the DNA probe diagnostics field.

Recent Developments

Recent developments in DNA Probe-based Diagnostics include the integration of artificial intelligence (AI) for faster data interpretation and the launch of more portable diagnostic devices. The shift toward at-home diagnostic kits has also gained momentum, with many new products entering the market that allow patients to conduct self-tests. Additionally, advancements in CRISPR technology are enhancing the accuracy and versatility of DNA probes, especially in gene editing applications.

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Curved Televisions Market Size, Share, Demand, Growth and Forecast 2024-2032

Curved Televisions Market provides in-depth analysis of the market state of Curved Televisions manufacturers, including best facts and figures, overview, definition, SWOT analysis, expert opinions, and the most current global developments. The research also calculates market size, price, revenue, cost structure, gross margin, sales, and market share, as well as forecasts and growth rates. The report assists in determining the revenue earned by the selling of this report and technology across different application areas.

Geographically, this report is segmented into several key regions, with sales, revenue, market share and growth Rate of Curved Televisions in these regions till the forecast period

North America

Middle East and Africa

Asia-Pacific

South America

Europe

Key Attentions of Curved Televisions Market Report:

The report offers a comprehensive and broad perspective on the global Curved Televisions Market.

The market statistics represented in different Curved Televisions segments offers complete industry picture.

Market growth drivers, challenges affecting the development of Curved Televisions are analyzed in detail.

The report will help in the analysis of major competitive market scenario, market dynamics of Curved Televisions.

Major stakeholders, key companies Curved Televisions, investment feasibility and new market entrants study is offered.

Development scope of Curved Televisions in each market segment is covered in this report. The macro and micro-economic factors affecting the Curved Televisions Market

Advancement is elaborated in this report. The upstream and downstream components of Curved Televisions and a comprehensive value chain are explained.

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The Rising Demand for Non-Radioactive Nucleic Acid Labeling Products: A 2030 Outlook

The global non-radioactive nucleic acid labeling product market is expected to grow from US$ 1.5 billion in 2023 to US$ 2.5 billion by 2030, at a CAGR of 7.5% during the forecast period. The growth of the market is attributed to the increasing demand for non-radioactive nucleic acid labeling products in various applications, such as molecular biology, genomics, and proteomics.

Non-radioactive nucleic acid labeling products offer several advantages over radioactive labeling products, such as safety, ease of use, and cost-effectiveness. Radioactive labeling products are hazardous to work with and require specialized training and equipment. Non-radioactive labeling products, on the other hand, are safe to use and do not require any special training or equipment. Additionally, non-radioactive labeling products are typically less expensive than radioactive labeling products.

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Non-radioactive nucleic acid labeling products are a safe and effective alternative to radioactive labeling products. They are used to label nucleic acids, such as DNA and RNA, with a variety of different labels, such as fluorescent dyes, haptens, and enzymes. These labeled nucleic acids can then be used in a variety of different applications, such as in situ hybridization (ISH), Southern blotting, Northern blotting, and Western blotting.

Key Market Trends:

The increasing adoption of non-radioactive labeling techniques in molecular biology and biotechnology research is the key market trend driving the growth of the non-radioactive nucleic acid labeling product market. Non-radioactive labeling techniques are safer, more convenient, and more sensitive than traditional radioactive labeling techniques.

Another key market trend is the growing demand for non-radioactive nucleic acid labeling products in the pharmaceutical industry. Pharmaceutical companies are using non-radioactive labeling products to develop new drugs and therapies.

Key Takeaways:

The global non-radioactive nucleic acid labeling product market is expected to grow from US$ 1.5 billion in 2023 to US$ 2.5 billion by 2030, at a CAGR of 7.5%

The growth of the market is attributed to the increasing demand for non-radioactive nucleic acid labeling products in various life science applications, such as DNA sequencing, PCR, and hybridization.

Other factors driving the market growth include the rising prevalence of infectious diseases, the growing demand for personalized medicine, and the increasing investment in life science research.

Regional Outlook:

North America is expected to be the largest market in terms of revenue, accounting for over 35% of the global market share in 2023.

The growth of the market in this region is attributed to the increasing demand for non-radioactive nucleic acid labeling products in the pharmaceutical and biotechnology industries.

Europe is expected to be the second-largest market, followed by Asia Pacific.

The growth of the market in Asia Pacific is attributed to the increasing investment in life science research and the growing demand for personalized medicine in this region.

Key Players:

Some of the key players in the global non-radioactive nucleic acid labeling product market include:

Thermo Fisher Scientific

PerkinElmer

Roche Diagnostics

GE Healthcare

Illumina

Agilent Technologies

Qiagen

Merck KGaA

Bio Rad Laboratories

Invitrogen

Promega

Segmentation:

By Product Type:

Enzymes

Probes

Kits

Others

By Application:

DNA Sequencing

PCR

Hybridization

Other Applications

By End User:

Pharmaceutical and Biotechnology Companies

Academic and Research Institutes

Hospitals and Diagnostic Centers

Other End Users

[myblogscmi]

Molecular Cytogenetics Market Is Estimated To Witness High Growth Owing To Increasing Demand for Genetic Testing

The global Molecular Cytogenetics Market is estimated to be valued at US$ 4,211.4 million in 2023 and is expected to exhibit a CAGR of 24.5% over the forecast period 2023-2030, as highlighted in a new report published by Coherent Market Insights.

A) Market Overview:

Molecular cytogenetics is a branch of genetics that focuses on the study of chromosomes and their abnormalities at a molecular level. It combines cytogenetic techniques with molecular biology to investigate the structure and function of chromosomes, as well as the genetic abnormalities associated with various diseases. The market offers a wide range of products such as fluorescent in situ hybridization (FISH) probes, comparative genomic hybridization (CGH) arrays, and karyotyping reagents, which are extensively used in research laboratories and diagnostic centers for genetic testing.

B) Market Dynamics:

The Molecular Cytogenetics Market is driven by two key factors. Firstly, there is a growing demand for genetic testing, especially in the field of personalized medicine, where genetic information is utilized to tailor treatment plans for individual patients. Genetic tests help in identifying genetic abnormalities that may cause diseases, enabling healthcare practitioners to make informed decisions regarding patient care. Moreover, advancements in technologies such as FISH and CGH arrays have made genetic testing more efficient and accurate, further contributing to market growth.

Secondly, there is a rising incidence of genetic disorders worldwide. According to the World Health Organization (WHO), birth defects are the leading cause of infant mortality and contribute significantly to childhood morbidity and disability. In addition, genetic disorders can also lead to adult-onset diseases such as cancer and neurodegenerative disorders. With an increasing awareness of the importance of early diagnosis, genetic testing has become an integral part of healthcare systems worldwide, driving the demand for molecular cytogenetics products.

C) Market Key Trends:

One key trend in the Molecular Cytogenetics Market is the increasing adoption of non-invasive prenatal testing (NIPT). NIPT is a genetic screening test that can detect the risk of certain chromosomal abnormalities in the fetus, such as Down syndrome, without the need for invasive procedures such as amniocentesis. The test is based on analyzing cell-free fetal DNA present in the maternal blood. NIPT offers several advantages over traditional methods, including higher accuracy, lower risk of complications, and earlier detection. This trend is expected to boost the demand for molecular cytogenetics products in the coming years.

D) SWOT Analysis:

Strengths:

- Advanced technologies such as FISH and CGH arrays offer high sensitivity and specificity in genetic testing.

- Increasing adoption of genetic testing in personalized medicine.

Weaknesses:

- High cost associated with molecular cytogenetics tests and equipment.

- Lack of awareness and accessibility in developing regions.

Opportunities:

- Growing application of molecular cytogenetics in oncology for cancer diagnosis and prognosis.

- Emerging markets such as Asia-Pacific offer significant growth opportunities.

Threats:

- Stringent regulatory requirements for genetic testing.

- Ethical concerns related to prenatal genetic testing.

E) Key Takeaways:

Paragraph 1: The global molecular cytogenetics market is expected to witness high growth, exhibiting a CAGR of 24.5% over the forecast period, due to increasing demand for genetic testing and rising incidence of genetic disorders.

Paragraph 2: North America is expected to dominate the market, followed by Europe, due to the presence of key players and a well-established healthcare infrastructure. However, the Asia-Pacific region is projected to be the fastest-growing market, owing to a growing population, rising healthcare expenditure, and increasing awareness about genetic testing.

Paragraph 3: Key players operating in the global molecular cytogenetics market include Abbott Laboratories, Affymetrix, Inc., Agilent Technologies, Inc., Applied Spectral Imaging, Inc., Bio-Rad Laboratories, and Thermo Fisher Scientific Inc., among others. These players focus on product innovation, collaborations, and acquisitions to sustain their market position and expand their product portfolios.

[markettrend24]

Fluorescence In Situ Hybridization Probe Market risks and challenges that the industry is facing

Fluorescence In Situ Hybridization Probe Market risks and challenges that the industry is facing

This report studies the Fluorescence In Situ Hybridization Probe Market with many aspects of the industry like the market size, market status, market trends and forecast, the report also provides brief information of the competitors and the specific growth opportunities with key market drivers. Find the complete Fluorescence In Situ Hybridization Probe Market analysis segmented by companies,…

[wemresearch]

Spatial Genomics and Transcriptomics Market Report 2022 to 2030 By Top Key Players, Types & Applications

The Spatial Genomics and Transcriptomics Market size was $163.8 million in 2020, and is expected to grow at a value of more than $470.55 million by 2030, registering a CAGR (Compound annual growth rate) of over 11% from 2022 to 2030.

Due to the rising potential of spatial genomic analysis as a cancer diagnosis tool and the arrival of the fourth generation of sequencing, the market for spatial genomics and transcriptomics will experience significant expansion. A desirable novel biomarker needed in many cancer types is genome placement. The use of spatial information as a diagnostic biomarker for many diseases was made possible by the discovery of spatial patterns in the genome for a number of medical problems. Biomarkers that enable more accurate classification between benign and malignant tumours are in increased demand. The need for spatial genomics analysis as a cancer detection tool is increasing as a result of this factor.

A research created by FutureWise Industry Research offers a thorough analysis of the market trends for spatial genomics and transcriptomics that will impact the expansion of the overall market. Additionally, it has comprehensive details on the profitability graph, SWOT analysis, market share, and regional expansion of this company. The study also provides information on the current status of important market participants in the examination of this industry's competitive landscape.

Spatial Genomics and Transcriptomics Market: Segmentation Analysis

Spatial Genomics and Transcriptomics Market by technology:

·         Spatial transcriptomics

Sequencing based methods

§  Laser capture microdissection

·         FFE tissue samples

·         Others

Transcriptome in-vivo analysis (TIVA)

In situ sequencing

Microtomy sequencing

·         IHC

·         Microscopy based RNA imaging techniques

Single molecule RNA fluorescence in-situ hybridization

Padlock probes/rolling circle amplification

Branched DNA probes

·         Spatial genomics

FISH

Microscopy-based live DNA imaging

Genome perturbation tools

Massively-parallel sequencing

Biochemical techniques

Others

The spatial transcriptomics section ruled the market with a revenue share of more than 80% in 2020 attributable to its high reception when contrasted with spatial genomic techniques for the transcriptomic study of single cells. The development of this section can likewise be ascribed to the accessibility of automated sequencing philosophies, for example, laser catch microdissection technique (LCM), to fulfil the growing need for nucleic acid sequencing of biological specimens or single cells.

Spatial Genomics and Transcriptomics Market by workflow:

Spatial imaging

Spatial analysis

Spatial sequencing.

Spatial Genomics and Transcriptomics Market by product type:

·         Instruments

By mode

§  Automated

§  Semi-automated

§  Manual

·         By type

Sequencing platform

IHC

Microscopy

Flow cytometry

Mass spectrometry

Others

·         Consumables

·         Software

Bioinformatics tools

Imaging tools

Storage and  management databases

Among these, Consumables Segment is expected to witness healthy growth during the forecast Period. The section is projected amplify substantially because of the rising occurrences of various chronic disease and cancer cases across the globe. Inferable from an increment in the rising rates, increasing R&D development are likely to push the market progression.

Spatial genomics and transcriptomics market by application: 

Translational research

Drug discovery & development

Others

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Top Key Players:-

Akoya Biosciences, Inc.

BioSpyder Technologies Inc.

Bio-Techne Corporation (Advanced Cell Diagnostics, Inc.)

Dovetail Genomics, LLC

Fluidigm Corporation

Genomic Vision SA, Illumina, Inc.

Lunaphore Technologies SA

Nanostring Technologies, Inc.

Natera Inc.

PerkinElmer Inc. (Horizon Discovery Group Plc.)

Rarecyte, Inc.

Rebus Biosystems, LLC

Resolve Biosciences

S2 Genomic

Seven Bridges Genomics

Singular Genomics System, Inc.

Tecan Group Ltd. (Nugen Technologies, Inc.)

Ultivue, Inc.

Veranome Biosystems LLC

Vizgen Corporation

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Frequently Asked Questions (FAQ):

Q1. What is the total market value of spatial genomics and transcriptomic market report ?

Q2. What would be forecast period in the market report?

Q3. What is the market value of spatial genomics and transcriptomic market in 2021?

Q4. Which is base year calculated in the spatial genomics and transcriptomic market report?

Q5. Which are the top companies hold the market share in spatial genomics and transcriptomic market?

Q6. Which is the most influencing segment growing in the spatial genomics and transcriptomic market report?

Q7. What are the key trends in the spatial genomics and transcriptomic market report?

Q8. What are the market values / growth % of emerging countries?

Q9. What is spatial genomics and transcriptomic?

Q10. What are spatial genomics and transcriptomic used for?

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Fluorescent In Situ Hybridization (FISH) Probe Market 2022: Global Industry Analysis and Opportunity and Forecast To 2029

Fluorescent In Situ Hybridization (FISH) Probe Market 2022: Global Industry Analysis and Opportunity and Forecast To 2029

Fluorescent In Situ Hybridization (FISH) Probe Market 2022-2028 A New Market Study, Titled “Fluorescent In Situ Hybridization (FISH) Probe Market Upcoming Trends, Growth Drivers and Challenges” has been featured on fusionmarketresearch. Description This global study of the Fluorescent In Situ Hybridization (FISH) Probe Market offers an overview of the existing market trends, drivers,…

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Global Flourescent in Situ Hybridization (FISH) Probe Market Size and Challenges to 2026

Global Flourescent in Situ Hybridization (FISH) Probe Market will exhibit a CAGR of 6.6% for the forecast period of 2019-2026

Global Flourescent in Situ Hybridization (FISH) Probe Market Analysis and Insights:

Global Flourescent in situ hybridization probe market is expected to register a substantial CAGR of 6.6% in the forecast period of 2019-2026. This rise in the market can be attributed to the increase in use of FISH probes for diagnosis of infectious viruses, initiatives taken by the government and rise in awareness among people for benefits of FISH probe technique.

Fluorescent in situ hybridization (fish) would help in the identification of position of genes. It is used in clinic for diagnosing the chromosomal abnormalities including duplications, deletions and translocations etc. FISH has wide applications in research labs and clinics for monitoring the after effects of therapies, tracking of cells after transplantation etc. Many developments are taking place in FISH market including DNA probe-based diagnostics which assists in the determination of suspected diseases caused by any bacteria.

Global Flourescent in Situ Hybridization (FISH) Probe Market Scope and Market Size:

By Technology

FISH, Q FISH, Flow-FISH, CISH, DISH

By Type

DNA, RNA, mRNA, miRNA

By Application

Cancer Research, Lung, Breast, Bladder, Hematological, Gastric, Prostrate, Cervical

Global Flourescent in Situ Hybridization (FISH) Probe Market Country Level Analysis:

The countries covered in Flourescent in situ hybridization probe market report are the U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

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Competitive Landscape & Global Flourescent in Situ Hybridization (FISH) Probe Market Share Analysis:

Flourescent in situ hybridization probe market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, regional presence, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Flourescent in situ hybridization probe market.

Major Players:

Oxford Gene Technology

Agilent Technologies Inc

PerkinElmer Inc

Horizon Discovery Group plc

BioDot

Sysmex Singapore Pte. Ltd

Major TOC of the Report:

Chapter One: Introduction

Chapter Two: Market Segmentation

Chapter Three: Market Overview

Chapter Four: Executive Summary

Chapter Five: Premium Insight

Chapter Six: COVID-19 Impact on Global Flourescent in situ hybridization probe Market

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[chitrakullkarni]

Fluorescent In Situ Hybridization (FISH) Probe Market PESTEL Analysis and Key Growth Opportunities

The global Fluorescent In Situ Hybridization (FISH) Probe Market is expected to display higher growth rate over the next seven years. Rapid surge in the fluorescent in situ hybridization probes market is credited to the rising demand for molecular diagnostic tools and increasing adoption of ISH technology. Growing prevalence of chronic diseases along with rising demand for rapid diagnostic techniques are anticipated to foster market growth over the forecast period.

Globally, the fluorescent in situ hybridization (FISH) probe industry is predicted to generate massive revenue over next seven years, providing numerous opportunities for market players to invest for research and development in the FISH probe market. The conventional methodologies such as clinical trials were influenced by factors such as the growing competition, rising prices of medicines and strict governmental laws to limit adverse effects on the environment. With advent of the In Situ hybridization devices, such factors are significantly diminished due to numerous advantages associated with fluorescent In Situ hybridization devices.

Benefits associated with adoption of fluorescent In Situ hybridization devices are superior performance, successful trials, reliability and short timeframes for execution of clinical trial, and cost-effectiveness. Rising prevalence of cancer-related diseases is expected to boost market demand fluorescent in situ hybridization probe industry over the upcoming years. In addition, increasing adoption of DNA probe-based diagnostics for identification of diseases that are caused by pathogen or bacteria is estimated to drive market growth.

Rise in the number of incidence related to genetic disorders, solid tumors, leukemia, autism, and other syndromes are predicted to stimulate market demand for FISH Probe over the forecast period. Fluorescent in situ hybridization probes offer an advanced analytical method to monitor gene aberration, including gene amplification and deletion. Fluorescent in situ hybridization probe (FISH Probe) is also responsible for gene copy number change, chromosome translocation, gene expression at RNA level, and bacterial detection.

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The fluorescent in situ hybridization probe market is broadly categorized into three major segments based on the application type such as research and development labs, hospitals & clinics, and companion diagnostics. The hospitals & clinics segment is growing rapidly in the with substantial revenue generation in the last few years. Growing popularity of fluorescent in situ hybridization probes in the hospitals & clinics segment is attributed to the broad range of application involving detection of genetic disorders, cancer, and infectious diseases.

The FISH probe industry is divided by region as North America, Europe, Asia-Pacific, Latin America and Africa. North America has shown major growth in recent years owing to the rise in the implementation of latest technologies in gene therapy, surge in number of research & development activities in the region and existence of well-established healthcare infrastructure.

Asia-Pacific region is estimated to hold major share in the FISH probes market with massive growth in forecast period. Countries such as India, China and Singapore are leading the Asia-Pacific market with rising healthcare expenditure, increasing disposable income, favorable government initiatives to promote use of advanced technologies in healthcare sector, and significant investment by leading industry players considering potential growth opportunities in the region.

The key players in the fluorescent in situ hybridization probes industry are Oxford Gene Technology IP Ltd., Life Science Technologies Ltd., PerkinElmer Inc., Abnova Co., Biosearch Technologies Inc., Genemed Biotechnologies, Inc., F. Hoffmann-La Roche AG, Abbott Laboratories, Inc., and Agilent Technologies Ltd.

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Global In Situ Hybridization (ISH) Market Analysis, Share, Growth, Industry Trends, Overview And Forecast To 2025

Global In Situ Hybridization (ISH) Market is expected to reach USD 1.84 billion by 2025. In Situ Hybridization (ISH) is a type of hybridization a method that permits for specific localization of an exact segment of nucleic acid inside a histologic section. That means it involves the use of labeled RNA probes or labeled DNA probes to detect complementary DNA or RNA targets in cytologic preparations or tissue sections. Synthetic oligonucleotides (PNA, LNA), Double-stranded DNA (dsDNA) probes, RNA probes (riboprobes), and Single-stranded DNA (ssDNA) probes are the majorly used ISH probes.

It can be labeled using two major techniques like Non-radioactive labels and radioactive isotopes. A labeled RNA or DNA probe can be used to hybridize to a known target DNA or mRNA sequence within a sample. This labeled RNA or DNA probe can then be detected by using an antibody to detect the label on the probe. The In Situ Hybridization (ISH) industry is estimated to grow at a significant CAGR of 7.3% over the future period as the scope and its applications are rising enormously across the globe. In Situ Hybridization (ISH) Market is segmented based on product type, technology, probe type, application, end use, and region.

Services, instruments, software, and kits & probes are the product types that could be explored in In Situ Hybridization (ISH) in the forecast period. The instruments sector accounted for the largest market share of In Situ Hybridization (ISH) industry and is estimated to continue its dominance in the upcoming years. This may be because of high demand from research laboratories and diagnostic centers. Also, these instruments are easy to handle, cost-efficient, and portable these factors may lead the sector in coming years. However, kits & probes sector is estimated to grow at highest CAGR in the coming years.

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The enhanced technology used in In Situ Hybridization (ISH) is Chromogenic In Situ Hybridization (CISH) and Fluorescent In Situ Hybridization (FISH) that could be explored in the future period. RNA probe and DNA probe are the two main types of probes that could be explored in In Situ Hybridization (ISH) in the foremost period. The DNA probes sector is estimated to account largest revenue shares of In Situ Hybridization (ISH) in the coming years. Whereas, RNA sector is estimated to grow at highest CAGR in the coming years.

The market may be categorized based on applications like infectious diseases, cancer, developmental biology, cytogenetics, and others that could be explored in the future period. Cancer sector accounted for the largest market share of In Situ Hybridization (ISH) and is estimated to grow at highest CAGR in the coming years. The reason could be growing occurrence of cancer and rising research in this sector. However, cytogenetics sector is estimated to grow at fastest pace in the coming years.

End users like academic institutes, research & diagnostic laboratories, contract research organizations (CROs), and others could be explored in In Situ Hybridization (ISH) Market in the forecast period. The research & diagnostic laboratories sector accounted for the largest market share of In Situ Hybridization (ISH) and is estimated to lead the overall market in the coming years. This may be because of growing applications of molecular cytogenetics in diagnostics, rising use of enhanced technology in genomics and molecular cytology, and rising initiative in cell research. However, CROs segment is estimated to grow at fastest pace in the coming years.

Globally, North America accounted for the largest market share of In Situ Hybridization (ISH) and is estimated to lead the overall market in the upcoming years. The reason behind the growth of overall market could be government involvement for development of novel diagnostic tools, availability of research funds, and developed research centers. The United States is a major consumer of In Situ Hybridization (ISH) in this region.

Instead, Europe and the Asia Pacific are also estimated to have a positive influence on the future growth. Europe is the second largest region with significant market share. However, Asia Pacific is estimated to grow at fastest pace with the highest CAGR in the foremost period. The aspects that may be ascribed to the growth comprise, growing awareness regarding advantages of In Situ Hybridization (ISH) technology in diagnostics and government initiative in R&D investments in the field of molecular biology. The developing countries like India and China are the major consumers of In Situ Hybridization (ISH) industry in the region.

The key players of In Situ Hybridization (ISH) Market are Oxford Gene Technology, Thermo Fisher Scientific, Advanced Cell Diagnostics, Inc., Leica BiosystemsNussloch GmbH, NeoGenomics Laboratories, Inc., BIOVIEW, Bio-Rad Laboratories, Inc., Agilent Technologies, PerkinElmer, Inc., and Merck KGaA. These players are concentrating on inorganic growth to sustain themselves amongst fierce competition. As such, mergers, acquisitions, and joint ventures are the need of the hour.

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Nucleic Acid Labeling Industry Supply Chain Analysis, Growth Opportunities, Top Companies, Revenue Growth and Business Development Report by 2026

Increasing healthcare expenditure, rise in disease diagnosis, increase in R&D spending, increase in genomics research, rising demand for personalized medicine, rise in enzymology research and advancements in tools for synthetic genome design are key factors contributing to high CAGR of Nucleic Acid Labeling during forecast period.

the global Nucleic Acid Labeling market valued at USD 1.56 billion in 2018 and is expected to reach USD 3.08 billion by the year 2026, at a CAGR of 8.6%. A wide variety of molecular and cellular biology procedures are dependent on a labeled or tagged nucleic acid. These behavior and functioning can be specifically studied via the attached label. Nucleic acids can be easily labelled with several tags that allows their detection and purification. These tags can be used to recover or identify other interacting molecules.  The integrity of the nucleic acid is preserved in this non-destructive reaction, which makes it useful for applications where it is necessary to use the intact sample.

Owing to the growing demand for nucleic acid labeling, the manufacturers are adapting strategic initiatives such as innovative launch systems to increase their product portfolio. For example, with the launch of PHOTOPROBE labeling systems, the total length of the original nucleic acid sample, instead of copies, is directly marked. Additionally, Nucleic Acid Labeling can also be used for applications involving protein interactions, such as gel change or drip analysis, it is generally advantageous to generate labeled probes at the end to avoid steric interference of the interaction. The nucleic acid transfer can provide valuable information on gene integrity and copy number, as well as a means of analyzing mRNA size and expression gene, nucleic acid labeling helps to characterize cells and tissues developed in vitro and often produce important clinical information when used in patient samples. Moreover, the availability of different labels and a wide range of detection systems improve the sensitivity and flexibility required for in situ hybridization, thus, eventually driving the market growth for nucleic acid labeling.

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The report provides extensive coverage of the supply chain, key players of the industry, consumer base, company profiles, production and consumption rate, primary applications, and other relevant data. It provides an in-depth assessment of the key companies operating in the market along with their company profiles, business overview, production and manufacturing capacity, product portfolio, financial standing, global position, and business expansion plans. It also studies recent mergers and acquisitions, joint ventures, product launches, partnerships, collaborations, and agreements among other. The report also provides insights into new entrants and their strategic alliances to gain a robust footing in the market.

Key Manufacturers in the Global Nucleic Acid Labeling  Market:

Promega Corporation, Thermo Fisher Scientific, Inc., General Electric Company, New England Biolabs, PerkinElmer, Inc., F. Hoffmann La-Roche AG, Vector Laboratories, Merck KGaA, Enzo Biochem, and Agilent Technologies.

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The report also provides an extensive regional segmentation to offer the readers key insights into the spread of the market over key geographical regions. It covers production and consumption patterns, import/export, supply and demand, consumer demand and behavior, key trends, and presence of key players in each region. The report also offer a country-wise analysis to impart a better understanding of the revenue growth of the market in each region.

North America (U.S., Canada,     Mexico)

Europe (U.K., Italy, Germany,     France, Rest of Europe)

Asia Pacific (India, Japan, China,     South Korea, Australia, Rest of APAC)

Latin America (Chile, Brazil, Argentina,     Rest of Latin America)

Middle East & Africa (Saudi     Arabia, U.A.E., South Africa, Rest of MEA)

Product Type (Revenue, USD Million; 2016–2026)

Reagents & Kits

Services

Technique Type (Revenue, USD Million; 2016–2026)

PCR

Nick Translation

Random Primer

In Vitro Transcription

Reverse Transcription

End Labeling

Label Type (Revenue, USD Million; 2016–2026)

Biotin-based

Fluorescent

Radioactive

End Use (Revenue, USD Million; 2016–2026)

Hospital

Clinic

Others

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Key Questions Addressed in the Report:

What is     the market size the global Nucleic Acid Labeling  market is expected to reach over the     forecast period? What is the expected CAGR?

What     are the key segments of the market?

What     are the key products and applications of the Nucleic Acid Labeling  market?

What     factors are expected to drive and restrain market growth over the forecast     period?

What     are the key outcomes of SWOT analysis and Porter’s Five Forces analysis?

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[myoliver123stuff]

Spatial OMICS Market is estimated to reach at $1584.22 Mnby 2030

The global Spatial OMICS market size is expected to be worth around US$ 584.22 Mn by 2030, according to a new report by Trends Market Research.

The global Spatial OMICS market size was valued at US$ 305.81 Mn in 2020 and is anticipated to grow at a CAGR of 15.05% during forecast period 2021 to 2030.

Growth Factors

Startups and well-established players continued their product development and launched novel solutions, democratized their offerings beyond innovators, and engaged in mergers & acquisitions. The spatial OMICS field originated from hyperplexed imaging; however, key players have shifted toward the development of spatial transcriptomics solutions and products.

Rapid advances in the sequencing of tissues, genes, and single cells have resulted in the emergence of spatial genomic sequencing. Spatial OMICS techniques offer quantitative gene expression data and visualization of DNA and RNA mapping within tissue sections. The development of novel technologies for spatial OMICS is anticipated to create lucrative opportunities for the fields of translational research as well as diagnostics.

The spatial genomics technology segment is expected to expand at the fastest CAGR throughout the forecast period owing to a rise in the launch of novel platforms. The integration of high-throughput solutions in transcriptomics, genomics, and proteomics studies has enabled determining the link between disease occurrence and genome position.

Report Highlights

The spatial transcriptomics segment dominated the market with a share of 73.56% in 2020. Continuous advancements in sequencing technologies have accelerated the transcriptomic study of single cells. For the comprehensive study of multicellular organisms, efforts are being taken to design novel solutions for high-throughput genomic analysis while maintaining the spatial information of the sample/tissue under observation or subcellular localization of analyzed DNA/RNA.

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The development of various in situ methods enhances the capabilities to explore spatial information in biological investigation. These methods have led to the convergence of function-oriented fields of biochemistry and molecular genetics with structure-focused fields such as histology and embryology, thereby enabling spatially resolved molecular investigation of biological processes.

The consumables segment accounted for the largest share of 63.01% in 2020 owing to the high utilization rate and launch of novel products. For instance, in March 2021, Bruker launched new consumables for the chemical cross-linking of proteins (XL-MS). The new PhoX cross-linker facilitates the purification of protein from XL-MS reaction complex mixtures. Moreover, the company plans to launch three cleavable cross-linkers for cleaving the cross-linkers generated in MS experiments.

The launch of new instruments is directly associated with the development of the consumables. Therefore, this drives the instruments as well as the consumables segment. In December 2020, NanoString announced the development of spatial molecular imager (SMI). It is a next-generation spatial OMICS platform designed for multiplexed protein and RNA analysis for single cells in FFPE tissue samples. The platform is expected to be launched by 2022.

The instrumental analysis segment dominated the market with a revenue share of 57.69% in 2020. The growth of the segment can be primarily attributed to substantial advancements being performed in instruments such as microscopy and mass spectrometry. Mass spectrometry is one of the most promising tools that is used for quantifying nucleic acid and proteins.

It has several advantages such as high resolution, high speed, and high-throughput operations for profiling of protein, which are later used for analyzing complex biological samples. This facilitates novel applications such as new drug development, biomarker discovery, and diagnostics.

The formalin fixation and paraffin-embedding (FFPE) segment held the largest share of 67.26% in 2020. FFPE is considered a standard sample type that is most used for the preservation of human tissue for clinical diagnosis, and hence it holds a major share in the global market. This technique is considered the best in researching tissue morphology for clinical histopathology and diagnostic purposes.

In addition, FFPE specimens are found in abundance in clinical tissue banks, which contributes to the segment growth. However, they are incompatible with single-cell level transcriptome sequencing owing to RNA degradation and RNA damage during storage and extraction. Hence, researchers are focusing on new approaches for increasing the application of FFPE in spatial transcriptomic studies.

The academic and translational research institutes segment dominated the market with a revenue share of 99.60% in 2020. An increase in the adoption of spatial OMICS to translate real-time tissue responses to an external agent increases the technology’s adoption in translational research. Translational studies in the field of genomics help researchers and healthcare practitioners analyze the behavior of human tissues and cells from different individuals in different environments.

This vital information may lead to the evolution of new and better ways to prevent diseases. For instance, single-cell transcriptomics is found to be useful for neuroscientists to understand cell types forming the brain. These methods help understand the spatial architecture of nervous tissues and evaluate the brain’s function. However, this further requires linking molecular cell types to physiological, morphological, and behavioral factors.

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North America accounted for the largest share of 54.80% in 2020. This can be attributed to the increasing prevalence of cancer, the growing demand for personalized medicine, well-developed healthcare facilities, and the availability of novel diagnostic techniques. The growing morbidity and mortality rates due to cancer and other metabolic, autoimmune, and inflammatory disorders have led to an increase in the need for developing novel therapies, thereby driving the market in this region.

In addition, companies operating in North America are launching new initiatives and programs for discovering and increasing translational applications, which is further contributing to the market growth. For instance, in March 2021, NanoString Technologies, Inc. launched the Technology Access Program (TAP) through which the company will analyze tissue samples of patients using the Spatial Molecular Imager platform and GeoMx Digital Spatial Profiler. Hence, such initiatives help in expanding spatial biology applications in the region.

Key Players

10x Genomics

Dovetail Genomics

S2 Genomics, Inc.

NanoString Technologies, Inc.

Seven Bridges Genomics

PerkinElmer, Inc.

Bio-Techne

Danaher Corporation

IonPath, Inc.

Millennium Science Pty Ltd.

Akoya Biosciences, Inc.

Fluidigm Corporation

Diagenode Diagnostics

Biognosys AG

Rebus Biosystems

Ultivue, Inc.

Vizgen Corp.

BioSpyder Technologies

Bruker

Brooks Automation, Inc.

Market Segmentation

Technology Outlook

Spatial Transcriptomics

Sequencing-based Methods

Laser capture microdissection (LCM), by tissue type

FFPE tissue samples

Others

Transcriptome in-vivo analysis (TIVA)

In situ sequencing

Microtomy sequencing

Microscopy-based RNA Imaging Techniques, by methodsSingle Molecule RNA Fluorescence In-Situ Hybridization (smFISH) Padlock Probes/ Rolling Circle Amplification Branched DNA probes

Spatial GenomicsFISH Microscopy-based Live DNA Imaging Genome Perturbation Tools Massively-parallel Sequencing Biochemical Techniques Others

Spatial Proteomics Imaging TechniquesMicroscopy Multiplexed Ion Beam Imaging Mass Spectrometry Immunofluorescence Techniques Centrifugation Techniques Others

Product Outlook Instruments By ModeAutomated Semi-automated Manual By TypeSequencing Platforms IHC Microscopy Flow Cytometry Mass Spectrometry Others Consumables SoftwareBioinformatics tools Imaging tools Storage and management databases

Workflow OutlookSample Preparation Instrumental Analysis Data Analysis

Sample Type OutlookFFPE Fresh Frozen

End-use Outlook (Revenue, USD Million, 2017 - 2028)Academic & Translational Research Institutes Pharmaceutical and Biotechnology Companies

The Spatial OMICS market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

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The report provides size (in terms of volume and value) of Spatial OMICS market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Spatial OMICS market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Spatial OMICS market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Spatial OMICS market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

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Fluorescent In Situ Hybridization (FISH) Probe Market Statistical Forecast and Analysis Report till 2022

August 19, 2021: The global Fluorescent In Situ Hybridization (FISH) Probe Market is expected to display higher growth rate over the next seven years. Rapid surge in the fluorescent in situ hybridization probes market is credited to the rising demand for molecular diagnostic tools and increasing adoption of ISH technology. Growing prevalence of chronic diseases along with rising demand for rapid diagnostic techniques are anticipated to foster market growth over the forecast period.

Globally, the fluorescent in situ hybridization (FISH) probe industry is predicted to generate massive revenue over next seven years, providing numerous opportunities for market players to invest for research and development in the FISH probe market. The conventional methodologies such as clinical trials were influenced by factors such as the growing competition, rising prices of medicines and strict governmental laws to limit adverse effects on the environment. With advent of the In Situ hybridization devices, such factors are significantly diminished due to numerous advantages associated with fluorescent In Situ hybridization devices.

Benefits associated with adoption of fluorescent In Situ hybridization devices are superior performance, successful trials, reliability and short timeframes for execution of clinical trial, and cost-effectiveness. Rising prevalence of cancer-related diseases is expected to boost market demand fluorescent in situ hybridization probe industry over the upcoming years. In addition, increasing adoption of DNA probe-based diagnostics for identification of diseases that are caused by pathogen or bacteria is estimated to drive market growth.

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Rise in the number of incidence related to genetic disorders, solid tumors, leukemia, autism, and other syndromes are predicted to stimulate market demand for FISH Probe over the forecast period. Fluorescent in situ hybridization probes offer an advanced analytical method to monitor gene aberration, including gene amplification and deletion. Fluorescent in situ hybridization probe (FISH Probe) is also responsible for gene copy number change, chromosome translocation, gene expression at RNA level, and bacterial detection.

The fluorescent in situ hybridization probe market is broadly categorized into three major segments based on the application type such as research and development labs, hospitals & clinics, and companion diagnostics. The hospitals & clinics segment is growing rapidly in the with substantial revenue generation in the last few years. Growing popularity of fluorescent in situ hybridization probes in the hospitals & clinics segment is attributed to the broad range of application involving detection of genetic disorders, cancer, and infectious diseases.

The FISH probe industry is divided by region as North America, Europe, Asia-Pacific, Latin America and Africa. North America has shown major growth in recent years owing to the rise in the implementation of latest technologies in gene therapy, surge in number of research & development activities in the region and existence of well-established healthcare infrastructure.

Asia-Pacific region is estimated to hold major share in the FISH probes market with massive growth in forecast period. Countries such as India, China and Singapore are leading the Asia-Pacific market with rising healthcare expenditure, increasing disposable income, favorable government initiatives to promote use of advanced technologies in healthcare sector, and significant investment by leading industry players considering potential growth opportunities in the region.

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The key players in the fluorescent in situ hybridization probes industry are Oxford Gene Technology IP Ltd., Life Science Technologies Ltd., PerkinElmer Inc., Abnova Co., Biosearch Technologies Inc., Genemed Biotechnologies, Inc., F. Hoffmann-La Roche AG, Abbott Laboratories, Inc., and Agilent Technologies Ltd.

Market Segment:

FISH Probe End-use Outlook (Revenue, USD Million, 2012 - 2022)

• Research

• Clinical

• Companion diagnostics

FISH Probe RNA Outlook (Revenue, USD Million, 2012 - 2022)

• mRNA

• miRNA

• Other

FISH Probe Application Outlook (Revenue, USD Million, 2012 - 2022)

• Cancer research

• Lung

• Breast

• Other

• Genetic diseases

• Genetic Diseases

• Other

FISH Probe Technology Outlook (Revenue, USD Million, 2012 - 2022)

• FISH

• Q FISH

• Flow-FISH

• Other

• CISH

• DISH

FISH Probe Market Regional Outlook (Revenue, USD Billion, 2012 - 2022)

• North America

• U.S.

• Canada

• Europe

• Germany

• UK

• Asia Pacific

• Japan

• China

• India

• Latin America

• Mexico

• Brazil

• MEA

• South Africa

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Fluorescence in situ hybridization (FISH) is a macromolecule recognition technique, which is considered as a new advent in the field of cytology. Initially, it was developed as a physical mapping tool to delineate genes within chromosomes. The accuracy and versatility of FISH were subsequently capitalized upon in biological and medical research. This visually appealing technique provides an intermediate degree of resolution between DNA analysis and chromosomal investigations. FISH consists of a hybridizing DNA probe, which can be labelled directly or indirectly. In the case of direct labelling, fluorescent nucleotides are used, while indirect labelling is incorporated with reporter molecules that are subsequently detected by fluorescent antibodies or other affinity molecules. FISH is applied to detect genetic abnormalities that include different characteristic gene fusions or the presence of an abnormal number of chromosomes in a cell or loss of a chromosomal region or a whole chromosome. It is also applied in different research applications, such as gene mapping or the identification of novel oncogenes.

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