#DNA and RNA Sample Preparation Market

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DNA and RNA Sample Preparation Market is Estimated to Witness High Growth Owing to Increasing Adoption

The DNA and RNA sample preparation market involves processes associated with isolation, extraction, purification and quantification of nucleic acids DNA and RNA from various sources like tissues, blood, sperm, cells etc. for downstream applications in genomics, molecular diagnostics, personalized medicine and others. The sample preparation is a critical and initial step before conducting various genomic tests including Next Generation Sequencing, polymerase chain reaction and other assays. Growing awareness and adoption of precision medicine and genetic/molecular testing is driving demand for efficient nucleic acid isolation and downstream analysis.

The Global DNA and RNA Sample Preparation Market is estimated to be valued at US$ 2262.46 Mn in 2024 and is expected to exhibit a CAGR of 5.8% over the forecast period 2024 To 2031. Key Takeaways Key players operating in the DNA and RNA sample preparation are Agilent Technologies, Inc., Becton, Dickinson and Company, Bio-Rad Laboratories Inc., DiaSorin S.p.A, F. Hoffmann-La Roche, Miroculus, Inc., Illumina, Inc., PerkinElmer, Inc., QIAGEN, Sigma Aldrich Corp., Tecan Group AG, and Thermo Fisher Scientific, Inc. Growing prominence of personalized medicine is creating opportunities for development of new sample preparation methods and kits which can extract nucleic acids from various types of samples. Rising incidence of chronic and infectious diseases worldwide is increasing diagnostic testing which will propel sample preparation market growth. Global expansion of key market players through acquisitions and partnerships with regional diagnostic labs and research institutes will further augment market revenues. Market Drivers Increasing funding for Genomic and genetic research from government bodies as well as private sector is one of the key factors driving the DNA and RNA Sample Preparation Market Size. Government initiatives aimed at large scale population screening and clinical testing for various genetic disorders, infectious diseases and cancers are also creating demand for high throughput nucleic acid preparation. Growing geriatric population and rising healthcare spending in developing nations also provides growth opportunities for market players in the forecast period.

PEST Analysis Political: Laws and regulations imposed by governments for research using DNA and RNA samples could impact the market. Changes in healthcare policies will also have effects. Economic: Factors like GDP growth, income levels, healthcare spending will drive demand. Rise in research activities and focus on precision medicine boost the market. Social: Growing awareness about personalized medicine and importance of genetic testing are important. Social trends also promote preventive healthcare and wellness. Technological: Advancements in fields like next generation sequencing, lab automation, bioinformatics are key for market growth. Miniaturization and portability of equipment expand applications. Developments in sample collection and storage methods improve efficiency. Geographical regions where the market in terms of value is concentrated include North America and Europe. North America accounts for the largest share in the global market due to presence of well-established healthcare industry and research institutes. Europe also captures notable share due to growing biotech sector and research funding. The Asia Pacific region is projected to be the fastest growing market during the forecast period. This is attributed to factors such as increasing healthcare expenditure, growing awareness, expanding biotech industry and rising government investments in research. Countries like China, India offer growth opportunities as they focus on healthcare infrastructure development.

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DNA and RNA Sample Preparation Market Future Trends to Look Out | Bis Research

DNA sample preparation refers to the series of techniques and procedures employed to isolate and purify DNA from various biological samples, such as blood, tissues, cells, and environmental samples. 

The global   DNA and RNA Sample Preparation Market is projected to reach $5,615.9 million by 2033 from $2,922.8 million in 2023, growing at a CAGR of 6.75% during the forecast period 2023-2033.

DNA and RNA Sample Preparation Market Overview

DNA sample preparation is a fundamental process in molecular biology, essential for obtaining high-quality DNA suitable for various analytical and experimental procedures. The process begins with the collection and proper storage of biological samples to prevent degradation.In both DNA and RNA sample preparation, the primary goal is to obtain nucleic acids that are free of contaminants and degradation, enabling successful and reproducible downstream analyses. 

Key Steps in DNA and RNA Sample Preparation Market

Sample Collection and Preparation 

Cell Lysis 

Removal of Contaminants 

Nucleic Acid Precipitation 

Purification 

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Market Segmentation

Product Type 

(i) Kits and Reagents 

(ii) Instruments 

(iii) Consumables 

Application Type 

(i) Clinical Diagnostics 

(ii) Research Applications 

(iii) Forensic Sciences 

(iv) Environmental Testings 

End Users 

(i) Academic and Research Institutes 

(ii) Hospitals and Diagnostics 

(iii) Pharmaceuticals and Biotechnology 

Recent Developments in the DNA and RNA Sample Preparation Market

Qiagen N.V. introduced two groundbreaking additions to its sample technologies portfolio, i.e., the TissueLyser III that facilitates high-throughput disruption of diverse biological samples and the RNeasy PowerMax Soil Pro Kit that isolates high-purity RNA from challenging soil samples using advanced Inhibitor Removal Technology.

PerkinElmer introduced the CHEF Magnetic Bead Cleanup System, providing automated nucleic acid purification through advanced magnetic bead technology. This novel system would help automate the nucleic acid purification process efficiently.

Conclusion

The DNA and RNA sample preparation market is poised for significant growth, driven by the increasing demand for high-quality nucleic acid samples in various applications, including clinical diagnostics, academic research, forensic science, and biotechnology.

In conclusion, the DNA and RNA sample preparation market is set to expand as technological advancements continue to improve the efficiency, accuracy, and reliability of sample preparation processes.

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Biotechnology Reagents and Kits Market will grow at highest pace owing to increasing R&D activities in biopharmaceutical companies

Biotechnology reagents and kits are used for several diagnostic and research applications including isolation, purification, and analysis of DNA and RNA. Some key products in this market include cell and tissue culture reagents, chromatography reagents, electrophoresis reagents, immunohistochemistry reagents, nucleic acid extraction and purification reagents, PCR reagents, flow cytometry reagents, electrophoresis reagents, and separation and filtration reagents. Growing funding for biotechnology research along with rising prevalence of chronic diseases has increased the demand for biotechnology reagents and kits. Advancements in biologics and personalized medicine require reagents and kits for molecular analysis of patient samples which has fueled market growth.

The Global Biotechnology Reagents and Kits Market is estimated to be valued at US$ 718.8 Mn in 2024 and is expected to exhibit a CAGR of 23% over the forecast period 2023 to 2030.

Key Takeaways Key players operating in the Biotechnology Reagents and Kits are Medtronic Plc, Hill-Rom Holdings, Inc. (Welch Allyn), iRythm Technologies, Inc., AliveCor, Inc., Vivalnk, Inc., Cardiac Insight Inc., VitalConnect, LifeSignals, Inc., Lâ€TMoreal Group, Dexcom, Inc., GENTAG, Inc., Abbott Laboratories, Koninklijke Philips N.V. and other prominent players. These players are focusing on new product development and launches to expand their product portfolio. For instance, in 2022 Medtronic Plc launched Clara Smart Pancreas System which uses RTSM technology to automatically suspend insulin delivery. The demand for biotechnology reagents and kits is growing owing to increasing demand of personalized medicine, genomics applications and cell and gene therapy research. Pharmacogenomics, companion diagnostics and molecular biomarkers are driving the need for reagents and assays utilized in the discovery, development and commercialization of personalized medicine. Growing R&D spending on developing new biologics and rising application of big data analytics in drug development is also fueling market growth. Technological advancements are expanding application of biotechnology reagents and kits in new areas. For example, next generation sequencing techniques have enabled large-scale sequencing of genomes which requires reagents for sample preparation and library preparation steps. Rapid diagnostics technologies are allowing point-of-care application of reagents for fast detection of infectious diseases. Automated instruments with integrated reagent kits are increasing efficiency and reproducibility of experiments in core labs. Market trends: 1. Growing preference for personalized medicine/ precision medicine. Biomarker discovery and validation requires biomarker detection assays which is propelling demand for immunohistochemistry, PCR and other reagents. 2. Increasing focus on contract research and contract manufacturing. CROs and CMOs require a continuous supply of biotechnology reagents and kits for conducting research and manufacturing activities on behalf of biopharma companies. Market Opportunities: 1. Emerging markets in Asia Pacific offer high growth potential. Countries like China, India and South Korea are witnessing increasing biotech research and bulk drug production which will drive the need for reagents in coming years. 2. Cell and gene therapy is a major area of focus. Reagents are essential for quality control testing, process development and scalable manufacturing of cell and gene therapies. This represents a lucrative opportunity for leading reagents players.

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Emerging Technologies Revolutionizing Epigenetics Research

The Epigenetics Market is witnessing remarkable growth propelled by advancements in genomic research, increasing understanding of epigenetic mechanisms, and their role in health and disease. Epigenetics, the study of changes in gene expression that do not involve alterations in the DNA sequence, has emerged as a promising field with applications in oncology, neurology, cardiology, and regenerative medicine.

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One of the key drivers of market growth is the rising prevalence of cancer and other chronic diseases, coupled with the growing recognition of epigenetic alterations as key drivers of disease progression and therapeutic resistance. Epigenetic modifications, such as DNA methylation, histone acetylation, and non-coding RNA regulation, play critical roles in regulating gene expression patterns and cellular functions. As a result, pharmaceutical companies and research institutions are increasingly investing in epigenetic research and drug discovery, driving the demand for epigenetics-focused technologies and services.

The development of epigenetic drugs, such as DNA methyltransferase inhibitors, histone deacetylase inhibitors, and bromodomain inhibitors, has opened new avenues for targeted cancer therapy and precision medicine. These drugs target specific epigenetic pathways dysregulated in cancer cells, offering the potential for more effective and less toxic treatment options compared to conventional chemotherapy. Additionally, epigenetic biomarkers have emerged as valuable tools for cancer diagnosis, prognosis, and treatment response prediction, further driving the demand for epigenetics-based diagnostics and companion diagnostics.

The Epigenetics Market is Valued USD 1.9  billion in 2022 and projected to reach USD 5.6 billion by 2030, growing at a CAGR of CAGR of 14.4% During the Forecast period of 2024-2032.

The epigenetics market is characterized by the presence of established players and innovative startups offering a wide range of products and services, including epigenetic assays, reagents, kits, and software solutions. Major players in the market include Illumina, Inc., Thermo Fisher Scientific Inc., QIAGEN N.V., Merck KGaA, and Abcam plc, among others. These companies provide comprehensive solutions for epigenetic research, from sample preparation and data analysis to validation and interpretation of epigenetic data.

Major vendors in the global Epigenetics Market are Bio-Rad Laboratories, Inc, Abcam plc, Abnova Corporation, Absolute Antibody, Active Motif, Inc, Bio-Rad Laboratories, Inc, BPS Bioscience, Inc., Chroma Medicine Eisai Inc., EpigenTek Group Inc, F. Hoffmann-La Roche, Illumina, Inc., Innomics Inc., Merck KGaA, Novartis AG, Promega Corporation., QIAGEN, Syndax Pharmaceuticals, ValiRx PLCand Others.

Emerging trends in the epigenetics market include the development of novel technologies for high-throughput epigenomic profiling, single-cell epigenetics, and spatial epigenetics. Recent advancements in next-generation sequencing (NGS), chromatin immunoprecipitation (ChIP), and DNA methylation analysis have enabled researchers to interrogate epigenetic landscapes at unprecedented resolution and scale, facilitating the discovery of novel epigenetic biomarkers and therapeutic targets.

Looking ahead, the epigenetics market is poised for continued growth driven by ongoing research efforts, technological advancements, and the translation of epigenetic discoveries into clinical applications. As our understanding of epigenetic regulation expands and the demand for personalized medicine grows, the epigenetics market is expected to play a pivotal role in advancing healthcare and addressing unmet medical needs. Collaborations between academia, industry, and regulatory agencies will be crucial in driving innovation and accelerating the development and adoption of epigenetics-based therapies and diagnostics.

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Massive Growth in the Life Sciences Industry Drives the NGS Sample Preparation Market

Removing RNA or DNA particles from tissues is vital for the making of libraries. Thus, RNA or DNA removal quality is important for attaining better results in NGS. Low-quality DNA or RNA removals can be polluted with proteins or carbon-based compounds like polyphenols. And it might make library preparation difficult in numerous forms. For example, for those libraries where polymerase chain…

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Next Generation Sequencing Market- Future Growth Prospects for the Global Leaders | Credence Research

The latest market report published by Credence Research, Inc. “Global Next Generation Sequencing Market: Growth, Future Prospects, and Competitive Analysis, 2016 – 2028. The Next Generation Sequencing (NGS) market currently holds a significant valuation of USD 5,809.8 million (2022). It is anticipated that by 2030, the market will surge to an astounding USD 21,485.69 million, reflecting an impressive CAGR of 20.54% from 2023 through 2030.

The Next Generation Sequencing (NGS) market refers to the industry and technology involved in advanced DNA sequencing techniques that have revolutionized the way genetic information is decoded. NGS, also known as high-throughput sequencing, is a cutting-edge method used to determine the sequence of nucleotides in DNA or RNA molecules quickly and at a large scale. It has significantly accelerated genomic research, personalized medicine, and various applications in fields such as agriculture, biotechnology, and clinical diagnostics.

Key components of the NGS market include:

Sequencing Platforms: These are the machines or instruments used to carry out the actual sequencing process. They are designed to process DNA or RNA samples, generate raw sequencing data, and facilitate data analysis.

Consumables: NGS requires various consumable reagents and kits, such as DNA libraries, primers, and sequencing reagents, which are essential for preparing and running samples on the sequencing platforms.

Bioinformatics and Data Analysis: The massive amount of data generated by NGS requires sophisticated bioinformatics tools and software for data analysis, alignment, variant calling, and interpretation.

Applications: NGS has a wide range of applications, including but not limited to genomics research, cancer genomics, infectious disease research, reproductive health, and pharmacogenomics.

The NGS market includes various components, such as sequencing instruments, consumables (e.g., reagents, cartridges), software for data analysis, and sequencing services offered by specialized laboratories. The market has seen substantial growth due to the expanding applications of NGS in research, clinical practice, and industry.

Next Generation Sequencing Market Scope

Next Generation Sequencing Market refers to the vast scope and potential of this rapidly advancing technology in the field of genomics. As scientists delve deeper into understanding the complexities of genetic code, Next Generation Sequencing (NGS) presents itself as an indispensable tool revolutionizing various industries. The Next Generation Sequencing Market encompasses a wide range of applications, including drug discovery, precision medicine, genetic testing, agriculture research, forensic analysis, and more.

With its ability to sequence massive amounts of DNA at once and generate highly accurate data quickly and cost-effectively, NGS has become instrumental in decoding complex diseases like cancer or rare genetic disorders. Moreover, it provides crucial insights into population genetics by analyzing large cohorts for personalized healthcare interventions at scale. The global market for Next Generation Sequencing continues to expand due to advancements in sequencing technologies such as Illumina platforms or Oxford Nanopore Technologies' portable devices that enable increased throughput with reduced costs per base pair sequenced.

This exponential growth is further driven by collaborations between industry leaders and academic institutions aiming to develop innovative approaches tailored to specific fields within genomics research. Overall, the Next Generation Sequencing Market holds immense promise for transforming our understanding of life's fundamental building blocks while offering unprecedented opportunities for breakthrough discoveries across diverse scientific domains.

Next Generation Sequencing Market Major Challenges and Risks

Next Generation Sequencing Market faces numerous challenges and risks that require careful consideration. Firstly, the high cost of Next Generation Sequencing (NGS) platforms poses a significant barrier to adoption among research institutions and healthcare providers. The expenses associated with acquiring sophisticated equipment, maintaining it, and training personnel can be daunting for many organizations.

Additionally, while NGS technology offers immense potential in enabling personalized medicine approaches and disease diagnosis, there are still limitations in terms of accuracy and reproducibility of results. This raises concerns regarding the clinical utility of NGS-based tests and their integration into routine patient care settings. Moreover, data management is becoming increasingly complex as the volume of genomic data generated by NGS continues to soar exponentially. Storage capacity, computational power requirements, data interpretation challenges, privacy concerns - all pose significant obstacles in managing this vast amount of information effectively.

Furthermore, regulatory hurdles related to intellectual property rights, reimbursement policies for genetic testing services offered through NGS platforms need to be addressed for widespread adoption in clinical practice worldwide. Lastly but importantly, keeping pace with rapidly evolving technological advancements necessitates continuous investment in research and development efforts by industry players competing within the Next Generation Sequencing Market to stay at the forefront of innovation amidst intense competition.

Browse 247 pages report Next Generation Sequencing Market By Technology (Sequencing by Synthesis, Sequencing by Ligation, Ion Semiconductor Sequencing, Nanopore Sequencing, Others), By End User (Research Institutes, Pharmaceuticals, Biotechnology Companies, Hospitals, Academic Institutes ), By Diagnostics (Cancer, Neonatal Screening, Infectious Disease, Reproductive Health, Genetic Testing) Growth, Future Prospects And Competitive Analysis 2020- 2030 – https://www.credenceresearch.com/report/next-generation-sequencing-market

Here are some of the significant trends that were prevalent:

Clinical Adoption: One of the most prominent trends was the increasing adoption of NGS in clinical settings. NGS was being used for diagnosing genetic disorders, cancer genomics, and identifying actionable mutations for personalized medicine. The integration of NGS into routine clinical practice was expected to drive substantial market growth.

Cost Reduction: Continuous efforts to reduce the cost of NGS were ongoing. Innovations in sequencing technology and workflow optimizations aimed to make NGS more affordable, which in turn made it more accessible to a wider range of researchers, clinicians, and institutions.

Expansion of Applications: NGS was finding applications beyond genomics research and diagnostics. It was being used in fields like metagenomics (studying microbial communities), epigenomics (examining modifications to DNA that can influence gene expression), and transcriptomics (studying RNA molecules) for a broader range of scientific inquiries.

Single-Cell Sequencing: Single-cell sequencing was a growing field within NGS. It allowed researchers to study individual cells, enabling a deeper understanding of cell heterogeneity in tissues and contributing to advances in immunology, neurobiology, and cancer research.

Emerging Markets: The NGS market was expanding into emerging markets, with Asia-Pacific, particularly China and India, showing significant growth potential. This expansion was driven by increased research activities, rising healthcare investments, and growing awareness of NGS technologies.

List of the prominent players in the Next Generation Sequencing Market:

10X Genomics

BGI

Agilent Technologies, Inc.

Bio-Rad Laboratories

GenapSys Inc.

F. Hoffmann-La Roche

Illumina, Inc.

Oxford Nanopore Technologies

NanoString Technologies, Inc.

Pacific Biosciences of California, Inc.

Why to Buy This Report-

The report provides a qualitative as well as quantitative analysis of the global Next Generation Sequencing Market by segments, current trends, drivers, restraints, opportunities, challenges, and market dynamics with the historical period from 2016-2020, the base year- 2021, and the projection period 2022-2028.

The report includes information on the competitive landscape, such as how the market's top competitors operate at the global, regional, and country levels.

Major nations in each region with their import/export statistics

The global Next Generation Sequencing Market report also includes the analysis of the market at a global, regional, and country-level along with key market trends, major players analysis, market growth strategies, and key application areas.

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DNA RNA Extraction Kit Market Size, Type, segmentation, growth and forecast 2023-2030

DNA RNA Extraction Kit Market

The DNA RNA Extraction Kit Market is expected to grow from USD 1.30 Billion in 2022 to USD 2.20 Billion by 2030, at a CAGR of 7.26% during the forecast period.

DNA RNA Extraction Kit Market Size

The DNA RNA Extraction Kit market research report analyzes the global market segment based on product type (DNA Extraction Kit, RNA Extraction Kit), end-use application (Hospital, Laboratory, Other), and geography (North America, Asia Pacific, Middle East, Africa, Australia and Europe), with the leading market players including Qiagen, Thermo Fisher Scientific, Merck KGaA, Roche, Cytiva, Agilent, Danaher, Promega, Bio-Rad, Bioneer, and Akonni Biosystems. The report dives deep into the dynamics of the market and the regulatory and legal factors, such as the increasing incidence of genetic disorders and the growing demand for personalized medicine and research on gene-based therapies. The market growth can be attributed to technological advancements, increasing research and development activities, and the need for quick, accurate, and efficient extraction of nucleic acids. The report anticipates continued market growth in the future.

DNA RNA Extraction Kit Market Key Player

Qiagen

Thermo Fisher Scientific

Merck KGaA

Roche

Cytiva

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DNA RNA Extraction Kit Market Segment Analysis

The DNA RNA Extraction Kit market targets customers in research and biotechnology laboratories, pharmaceutical companies, academic institutions, and diagnostic centers. The increasing demand for effective and efficient research tools for genetic analysis and clinical diagnostics is driving the revenue growth of the DNA RNA Extraction Kit market. The rising incidence of genetic diseases, cancer, and infectious diseases have led to increased demand for DNA RNA Extraction Kits as a primary step in genetic analysis and diagnosis.

One of the latest trends in the DNA RNA Extraction Kit market is the development of fully automated and high-throughput extraction systems, which enable faster and more efficient extraction of DNA and RNA from different sample types. Moreover, the growing popularity of personalized medicine and genomic-based research is expected to fuel the demand for DNA RNA Extraction Kits in the coming years.

The major challenge faced by the DNA RNA Extraction Kit market is the high cost of these kits, which may limit their accessibility, particularly in developing countries. Additionally, quality control issues in sample preparation and the lack of standardization in DNA RNA extraction protocols may also restrain the growth of the market.

The main findings of the DNA RNA Extraction Kit market report suggest that North America holds the largest share due to the presence of major market players in the region, while the Asia-Pacific region is expected to witness the fastest growth due to the rising demand for molecular diagnostics in the region.

The report recommends market players to focus on product innovation, developing cost-effective and easy-to-use DNA RNA Extraction Kits, and expanding their global reach through strategic partnerships and collaborations. Additionally, the report suggests that regulatory bodies should establish standardized protocols for DNA RNA extraction to ensure consistency and reliability in research and clinical diagnostics.

This report covers impact on COVID-19 and Russia-Ukraine wars in detail.

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Market Segmentation (by Application):

Hospital

Laboratory

Other

Information is sourced from www.reportprime.com

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DNA and RNA Sample Preparation Market Analysis by Size, Share, Growth, Trends up to 2032

The DNA and RNA sample preparation market is a crucial component of the rapidly advancing field of molecular biology and genomics. Sample preparation is the initial step in any genetic analysis, whether it's for research, diagnostics, or forensic purposes. It involves the extraction, purification, and concentration of DNA and RNA from various biological samples, such as blood, tissues, or saliva. This market has witnessed significant growth in recent years, driven by the increasing demand for personalized medicine, diagnostics, and research applications.

One key driver of the DNA and RNA sample preparation market is the expanding applications in clinical diagnostics. With the growing understanding of genetic variations and their links to diseases, there is a rising need for accurate and efficient sample preparation techniques to identify genetic mutations, biomarkers, and disease-associated genes. This has led to the development of innovative and automated sample preparation technologies, enabling high-throughput processing and enhancing the precision of diagnostic tests.

Moreover, the advent of next-generation sequencing (NGS) technologies has played a pivotal role in propelling the market forward. NGS requires high-quality DNA and RNA samples, and the demand for NGS-based research and clinical applications has driven the development of more sophisticated and efficient sample preparation methodologies. These advancements are not only improving the quality and quantity of extracted genetic material but also reducing the turnaround time, making genomics research and personalized medicine more accessible.

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In addition to clinical diagnostics and research, the DNA and RNA sample preparation market is also benefiting from the expanding use of genomics in agriculture, forensics, and biotechnology. As the field continues to evolve, the market is likely to witness continued innovation and growth, with a focus on automation, standardization, and cost-efficiency. This market will remain a critical enabler of advancements in genomics, contributing to our understanding of genetics and its applications in various fields, including healthcare, agriculture, and beyond.

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RNA-Sequencing & Analysis Market Industry Share & Growth Leaders

RNA-Sequencing & Analysis (RNA-seq) Market, By Product and Services (RNA Sequencing Platforms and Consumables, Sample Preparation Products, RNA Sequencing Services, Data Analysis, Storage and Management),Technology (Sequencing By Synthesis, Ion Semiconductor Sequencing, Single-Molecule Real-Time Sequencing, Nanopore Sequencing), Application (Expression Profiling Analysis, Small RNA Sequencing, De Novo Transcriptome Assembly, Variant Calling and Transcriptome Epigenetics), End User (Research and Academia, Hospitals and Clinics, Pharmaceutical and Biotechnology Companies, Other End Users) and region (North America, Europe, Asia-Pacific, Middle East and Africa and South America).

The Global RNA-Sequencing & Analysis (RNA-seq) Market size was estimated at USD 2.8 billion in 2022 and is projected to reach USD 8.7 billion in 2030 at a CAGR of 17.7% during the forecast period 2023-2030.

RNA-seq is a widely used technique that provides comprehensive insights into the genomic makeup of an organism or cell. This technique is used in both traditional and non-traditional applications, such as identifying gene expression patterns, detecting mutations, and studying epigenetic modifications. The demand for better sequencing-based diagnostics has led to the development of novel sequencing technologies that can provide more accurate and reliable results. High-throughput sequencers and portable units are two examples of such technologies that have become increasingly popular due to their ability to generate large amounts of data quickly and efficiently.

Next-generation sequencing (NGS) technology is a relatively new technology that has gained immense popularity since its launch due to its ability to provide advanced and comprehensive genetic insights. NGS technology is widely used in both traditional and non-traditional applications, such as in research, clinical diagnostics, and personalized medicine, to analyze DNA and RNA sequences. The growing demand for enhanced sequencing-based diagnostics has led to the development of new sequencing technologies that offer improved accuracy, speed, and cost-effectiveness.

 RNA sequencing is a technique used to determine the sequence of nucleotides in RNA molecules, which can provide valuable information about the virus's genetic makeup. Single-cell RNA sequencing, stranded RNA sequencing, and ultra-low input RNA sequencing are different methods used to study the virus's features and epidemiology across diverse countries. Single-cell RNA sequencing allows researchers to study individual cells and their gene expression patterns, while stranded RNA sequencing can determine the directionality of RNA molecules. Ultra-low input RNA sequencing is used when only a small amount of RNA is available for analysis.

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Delvens Industry Expert's Standpoint

Next-generation sequencing (NGS) is a high-throughput DNA sequencing technology that has revolutionized the field of genomics. Paired-end (PE) sequencing is a type of NGS that allows for the simultaneous sequencing of both ends of DNA fragments in a library. This technique produces twice as many reads as single-end sequencing, which only sequences one end of the DNA fragment. The forward and reverse reads produced by PE sequencing are aligned as reading pairs, which improves the accuracy of read alignment and enables the detection of insertions and deletions (indels) in the DNA sequence. Indels are important genetic variations that can cause diseases or affect an individual's response to drugs. The ability to detect indels is not achievable with single-read data, which makes PE sequencing a more powerful tool for genomic research. The paired-end strategy is the most modern and well-liked technique among researchers because of its ability to produce high-quality sequencing data and detect genetic variations that are not detectable by other sequencing methods.

Key Findings

On the basis of product and services, these are the products that are used to prepare the RNA samples for sequencing. RNA samples need to be extracted from the cells or tissues and then purified before they can be sequenced. Sample preparation products include kits, reagents, and instruments that are used for RNA extraction, purification, and quality control. services that are offered by sequencing companies or core facilities. Sequencing services include sample processing, library preparation, sequencing, and data analysis. These services are useful for researchers who do not have access to sequencing instruments or who do not have the expertise to perform sequencing themselves. RNA sequencing generates large amounts of data that need to be processed, analyzed, and stored. Data analysis includes quality control, alignment, quantification, and differential expression analysis.  

On the basis of technology, Sequencing by Synthesis is a method of DNA sequencing that involves the use of fluorescently labeled nucleotides to identify the sequence of the DNA strand. This method is commonly used in next-generation sequencing (NGS) technologies. Ion Semiconductor Sequencing is a type of NGS technology that uses a semiconductor chip to detect changes in pH caused by the release of hydrogen ions during DNA synthesis. This method is known for its speed and low cost. Single-molecule Real-time Sequencing is another NGS technology that uses a process called zero-mode waveguides to observe the synthesis of DNA in real-time. This method is known for its ability to detect modifications to DNA, such as methylation. Nanopore Sequencing is a third type of NGS technology that uses a nanopore to detect changes in electrical current as DNA strands pass through the pore. This method is known for its ability to sequence long DNA fragments and detect modifications to DNA.  

On the basis of Application, Expression Profiling Analysis refers to the process of measuring the expression levels of genes in a given sample. This is done by sequencing the RNA molecules present in the sample and analyzing the resulting data to determine which genes are being transcribed and at what levels. Small RNA Sequencing is a specialized type of RNA sequencing that focuses on the small RNA molecules present in a sample. These molecules are typically less than 200 nucleotides in length and play important roles in gene regulation and other cellular processes. De Novo Transcriptome Assembly is the process of reconstructing the complete set of RNA transcripts present in a sample, without the need for a reference genome. This is done by assembling short RNA sequencing reads into longer contiguous sequences, which can then be annotated and analyzed.  

The market is also divided into various regions such as North America, Europe, Asia-Pacific, South America, and Middle East and Africa. North America dominating the NGS-based RNA-sequencing market due to the increasing initiatives and funds from the government for genomics research, growing occurrences of chronic diseases, adoption of RNA-Seq products.

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Regional Analysis

North America to Dominate the Market

North America dominating the NGS-based RNA-sequencing market due to the increasing initiatives and funds from the government for genomics research.  

Asia-Pacific is expected to grow at the highest growth rate in the forecast period of 2022 to 2029 due to the increasing levels of investment for research activities and occurrence of better health facilities.

Competitive Landscape

Illumina Inc. (US)

Thermo Fischer Scientific Inc. (US)

Oxford Nanopore Technologies plc (UK)

Agilent Technologies, Inc. (US)

BGI (China)

PerkinElmer Inc. (US)

QIAGEN (Germany)

Eurofins Scientific (Luxembourg)

F. Hoffmann-La Roche Ltd (Switzerland)

Takara Bio Inc. (Japan)

GENEWIZ, Inc. (US)

Hamilton Company (US)

Macrogen Inc. (South Korea)

Zymo Research Corporation (US)

Tecan Trading AG (Switzerland)

Recent Developments

In July 2022, Illumina Inc launched Illumina DRAGEN v4.0, an accurate and comprehensive secondary analysis platform.  

In January 2021, Oxford Nanopore Technologies collaborated with NVIDIA to integrate the NVIDIA DGX Station A100 into Oxford Nanopore’s ultra-high-throughput sequencing system, PromethION.

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NGS Sample Preparation Market Share, Top Operating Players, Recent Enhancements and Regional Analysis 2032

The global NGS sample preparation market is expected to be valued at $5441.1 million by 2032, up from $1321.8 million in 2022, and to grow at a 13.7% CAGR during the forecast period (2022-2032).

DNA contains the blueprints of life. Within its structures are the codes required for the assembly of proteins and non-coding RNA – these molecular machineries affect all the biological systems that create and maintain life. By understanding the sequence of DNA, researchers have been able to elucidate the structure and functisimultaneously enabled the sequencing of thousands to millions of DNA moleculesenabled the sequencing of thousands to millions of DNA molecules simultaneously.

This technology involves steps such as library preparation followed by clone amplification and cyclic array sequencing. This technology is used for applications including human whole genome sequencing (WGS), whole exome sequencing, targeted sequencing using panels of a few to thousands of genes, and expression profiling.

NGS Sample Preparation Market: Drivers and Restraints NSG samples are being used for the sequencing of genomes. These genomes are being used for the preparation of specialized medicines. Increasing prevalence of genetic disorders is driving the growth of this market. Increasing need for the personalized medicines and clinical diagnosis is driving the growth of NGS sample preparation market. Technological advancements in sample preparation procedures and kits to standardize and simplify steps are driving the growth of NGS sample preparation market.

NGS Sample Preparation Market: Overview NGS has revolutionized the genome sequencing market. NGS sample preparation market is expected to show significant growth over forecast period. Increasing need for personalized treatment is driving the growth of this market. Increase in the healthcare spending and improvement in the healthcare technology are the major factors for the growth of NGS sample preparation market. Increasing incidence of disease conditions like cancer and use of NGS for diagnostic purpose in cancer and management or treatment of disease the boosting the growth.

Aging population is also expected to drive the growth of NGS sample preparation market. Single molecule real time sequencing is expected to be fastest growing segment due to real time preparation of samples. Drug discovery and diagnostic application are expected be highest revenue generating and fastest growing NGS sample preparation segments. Biopharmaceutical companies are biggest user of NGS samples as these companies are focusing on development of new drugs.

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NGS Sample Preparation Market: Region Wise Outlook

Geographically, the NGS sample preparation market can be segmented as North America, Latin America, Western Europe, Eastern Europe, Asia Pacific Excluding Japan, Japan and Middle East & Africa. North America is most attractive region for the NGS sample preparation market attributing to the presence of key biopharmaceutical players in this region and technological advancements. Followed by which is Europe and Japan. These markets are also growing significantly due to the focus of research institutes on development of new methods of NGS sample preparation and aging population. Asia Pacific excluding Japan is also expected to show significant growth in NGS sample preparation market due to improving healthcare infrastructure and increasing healthcare expenditure.

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DNA and RNA Sample Preparation Market Future Trends to Look Out | Bis Research

DNA and RNA sample preparation is a crucial step in molecular biology research, diagnostics, and various biotechnological applications. Proper sample preparation ensures the integrity, purity, and stability of nucleic acids, which are essential for downstream analyses such as PCR, sequencing, and gene expression studies. 

The global nucleic acid sample preparation market is projected to reach $5,615.9 million by 2033 from $2,922.8 million in 2023, growing at a CAGR of 6.75% during the forecast period 2023-2033.

DNA and RNA Sample Preparation Overview

Understanding of the key principles and methods involved in preparing DNA and RNA samples for analysis Importance of Sample Preparation, Sample Collection, Extraction of nucleic acid, quality assessment, DNA preparation, RNA preparation, quality control storage prevention 

Grab a look at the free sample page for more understanding click here !

Key Market Players 

 Agilent Technologies, Inc.

 Autogen, Inc.

 Bio-Rad Laboratories, Inc.

Roche AG

Merck KGaA

and many others  

The Nucleic Acid Isolation and Purification Market has made an impact in the following ways:

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Market Segmentation

Product Type 

End Users 

Applications 

Geography 

Various different applications involved are as follows 

Polymerase chain reaction 

Sequencing 

Gene Expression 

Molecular Diagnostics

Epigenetics and Chromatin Analysis

Drug Discovery and Development  

 Market Drivers for DNA and RNA Sample Preparation Market 

Advancements in Genomic Research

Rising Demand for Molecular Diagnostics

Increasing Applications in Drug Discovery and Development

Rising Incidence of Infectious Diseases and Genetic Disorders

Demand for Point-of-Care Testing (POCT) Solutions

Recent Developments in the Nucleic Acid Sample Preparation Market

Qiagen N.V. introduced two groundbreaking additions to its sample technologies portfolio, i.e., the TissueLyser III that facilitates high-throughput disruption of diverse biological samples and the RNeasy PowerMax Soil Pro Kit that isolates high-purity RNA from challenging soil samples using advanced Inhibitor Removal Technology. Qiagen announced the launch of the QIAseq Normalizer Kits that give researchers a fast, convenient, and cost-effective method to pool different DNA libraries for best-quality results from next-generation sequencing (NGS) runs.

PerkinElmer introduced the CHEF Magnetic Bead Cleanup System, providing automated nucleic acid purification through advanced magnetic bead technology. This novel system would help automate the nucleic acid purification process efficiently. PerkinElmer (Revvity, Inc.) rebranded its diagnostics and life sciences business as Revvity. This strategic move marked a new identity and focus for the company's ventures in these sectors.

Conclusion

As the demand for accurate, reliable, and efficient DNA and RNA sample preparation continues to rise, there is a growing emphasis on developing automated, integrated, and cost-effective solutions to meet the evolving needs of researchers, clinicians, and diagnostic laboratories. The convergence of cutting-edge technologies, strategic partnerships, and market expansion efforts is expected to drive the DNA and RNA sample preparation market forward, facilitating advancements in genomic medicine, precision diagnostics, and therapeutic development. Overall, the future of the DNA and RNA sample preparation market appears promising, with ample opportunities for innovation, growth, and impact across various sectors of the life sciences industry.

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Single Cell Analysis Market 2022 by Manufacturers, Regions, Type and Application, Forecast to 2030

Global Single Cell Analysis Market size was at US$ 3.1 Billion in 2021, and it is predicted that it will reach a valuation of US$ 10.99 Billion by the end of 2030 with an annual development rate (CAGR) of 15.10% between 2022 and 2030.

Single-cell analysis has been used to learn more about how cellular functionality is implemented. It necessitates an understanding of many biological components such as protein composition, DNA, and RNA, as well as metabolites such as pigments. A single-cell analysis approach is a method for interpreting cellular and functional variations in a single cell.

Due to new emerging approaches in which genomic technologies are applied at the single cell level rather than to all cells collectively, Single Cell Genomics is a rapidly growing business. By distinguishing the contributions of single cells to the diversity of ecosystems and species, single cell genomic technologies are breaking new ground. Single cell genomics is also revealing new information about a variety of biological systems, ranging from microbial ecosystem diversity to human cancer genetics.

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The business models, major strategies, and respective market shares of some of the most notable players in this sector are all examined in depth in this Single Cell Analysis System market study. The comprehensive analysis includes market statistics in terms of revenues, segment-wise data, region-wise data, and country-wise data, as well as an in-depth commentary on the key affecting variables. This report is one of the most comprehensive documents available, covering every aspect of the growing Single Cell Analysis System market.

Global Single Cell Analysis Market: Segmentations

Single Cell Analysis Market based on product type

• Consumable

o Microplates

o Beads

o Reagents

o assay kits (Immunoassays and cell based assays)

o Other Consumables

• Instrument

o flow cytometers

o NGS Systems

o PCR Instruments

o Spectrophotometers

o Microscopes

o cell counters

o HCS systems

o Microarrays

o Others

Single Cell Analysis Market based on Cell Type

• Human cells

• Animal Cells

• Microbial Cells

Single Cell Analysis Market based on workflow

• Single cell isolation & library preparation

• Downstream analysis

• Data analysis

Single cell analysis market based on Technique

• Flow Cytometry

• Next-generation sequencing

• Polymerase Chain Reaction

• Microscopy

• Mass Spectrometry

• Others

Single Cell Analysis Market based on Application

• Research Application

o Cancer

o Immunology

o Neurology

o stem cell

o Others

• Medical Applications

o Non-invasive prenatal diagnosis

o in Vitro Fertilization

o circulating tumor cell detection

Single Cell Analysis Market based on End-User

• Academic & Research Laboratories

• Biotechnology & Pharmaceutical Companies

• Hospitals & Diagnostic Laboratories

• Cell Banks & IVF Centers

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Next Generation Sequencing Market Outlook Analysis, Segmentation By Mode of Delivery and End-User to 2025

Next Generation Sequencing Market Highlights :

There are various diseases that have their roots in genetics such as cancer, diabetes, Alzheimer’s, arthritis, heart disease, etc. To discover viable treatment for these diseases, researchers are looking to discern how genes work. The next-generation sequencing market has been gaining impetus due to the fact that next-generation sequencing is integral to the field of genomics.

The NGS technologies are implemented for several applications, including whole-genome sequencing, de novo assembly sequencing, resequencing, and transcriptome sequencing at the DNA or RNA level. The successful application of next-generation sequencing can lead to predicting genes, protein-coding regions, and pathways.

Illumina, Helicos Biosciences, Thermo Fisher Scientific, Roche, Pacific Bioscience, ABI Life Technologies, and Oxford Nanopore are some of the companies that are implementing different NGS technologies which in turn will augment global next-generation sequencing market which is estimated to reach at a CAGR of 18.05% over the forecast period and USD 20,347.45 Million by 2025.

Next Generation Sequencing Market Segmentation :

The Next Generation Sequencing Market has been classified by Technology, Service and Product, Application, and End-User.

By technology, the next-generation sequencing market has been segmented as whole-genome sequencing, methyl sequencing, whole-exome sequencing, targeted resequencing, CHIP sequencing, RNA sequencing, and de novo sequencing.

By service & product, the next-generation sequencing market has been segmented as consumables, sample preparation, sequencing services, and platforms and services for platforms.

By application, the NGS market has been segmented as genetic screening, drug discovery, diagnostics, agriculture and animal research, and others.

End-users segmentation of the next generation sequencing market includes academic institutes and research centers, pharmaceutical and biotechnology companies, hospitals and clinics, and other end-users.

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Next Generation Sequencing Market Regional Analysis :

Owing to the rising number of funds being granted for research into genomics and initiatives adopted by the government to rein in cases of genetically occurring diseases and demand to improve the healthcare sector is estimated to augment the growth of the next-generation sequencing market in North America. Increased competition among market players as well as acquisitions and mergers are expected to drive the growth of the market in the region.

The next-generation sequencing market in Europe is expected to hold the second-largest revenue share due to the presence of some of the leading next-generation sequencing technology companies and an educated population inclined on the advancement of next-generation sequencing technology.

Though diverse regulations and a fragmented NGS market might restrain the growth of the market in the region, favorable funding scenario and immense support for scientific research would augment the next-generation sequencing market in the region.

The next-generation sequencing market share in Asia-Pacific is projected to witness expansion over the coming years due to growing demand for advanced technology and access to enhanced treatment facilities, better adoption of advanced genomics, an increase in disposable income, and rising investments in diverse treatment options by pharmaceutical companies.

Due to lack of technical knowledge, an underdeveloped healthcare sector, and poor medical facilities the next-generation sequencing market in the Middle East and Africa is expected to garner the smallest share.

Next Generation Sequencing Market Competitive Landscape :

Some of the Key Players in the Global Next-Generation Sequencing Market Illumina, Inc., Thermo Fisher Scientific, Inc., Pacific Biosciences of California, Inc., BGI, PerkinElmer, Agilent Technologies, QIAGEN N. V., Macrogen Inc., Oxford Nanopore Technologies, Ltd., and Eurofins Scientific.

Next Generation Sequencing Industry News :

Recently, Thermo Fisher Scientific launched its Ion Torrent Genexus System, the first fully integrated, next-generation sequencing platform that delivers results economically in a single day. This turnkey solution is designed to enable local hospitals to adopt NGS testing.

According to a study published in Clinical Lung Cancer local hospitals are severely challenged when it comes to providing NGS-based genomic testing at present even though hospitals are where most patients are treated. Due to limitations to NGS adoption, such as product complexity and cost, the vast majority of local molecular laboratories rely on single-gene tests.

Some laboratories even have to outsource testing for more comprehensive NGS analysis as single-gene tests fail to provide a complete genomic profile of a tumor. Ion Torrent Genexus System is expected to solve many of the problems faced by hospitals when it comes to gene testing thus increasing growth scope for next-generation sequencing.

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