#Corneal Ulcer Treatment

[rahulp3]

Corneal Ulcer Treatment Market Size and Growth, Industry Analysis, Trends, CAGR, Segmentation, Opportunities, and Forecast 2022 To 2029

The Corneal Ulcer Treatment Market is anticipated to develop as a result of rising contact lens usage, novel treatment options, such as anti-amoebic medications, and well-established supply chain operations. The market for corneal ulcer therapy is expected to grow significantly at 5.7% CAGR from 2022 to 2029, reaching an estimated market value of about US$ 867.3 Million as of 2022.

According to Future Market Insights, the market share for antibiotics is predicted to reach a huge 76.4% in 2021.The general public as well as ophthalmologists are becoming more aware of corneal ulcers because to a number of activities by international as well as regional organisations, governments, etc. to end preventable blindness caused by contact lens use.

Get your PDF Sample Report with Latest Market Information @ https://www.futuremarketinsights.com/reports/sample/rep-gb-6953

Further, universities and non-profit organizations arranging eye check-up camps further aids in enhancing awareness about corneal ulcers.

FMI – a well-established name in the market research domain – forecasts that, the corneal ulcer treatment market will experience a major upturn in the coming years, reaching a valuation of US$ 1.27 Bn by 2029.Key Takeaways of Corneal Ulcer Treatment Market StudyTreatment of broad-spectrum corneal ulcers using antibiotics is expected to gain traction and contribute more than 75% of revenue share during the forecast period.Growing bacterial keratitis requiring antibiotics for treatment will contribute significantly to the revenue share of the segment.Eye drops or eye ointments dominate the market by form type, as these are relatively cheaper and do not require other interventional and oral route for drug delivery.By distribution channel, retail pharmacies are expected to gain more than 50% of market share during the forecast period.North America is dominating the global corneal ulcer treatment market, while East Asia is expected to offer lucrative growth opportunities, owing to rising healthcare infrastructure and industrialization.Acquisition – Key Strategy Followed by Leading ManufacturersLeading manufacturers in the corneal ulcer treatment market are focusing on geographical expansion as well as increased product offerings through partnerships and acquisitions.

Ask from Market Research Expert@ https://www.futuremarketinsights.com/ask-question/rep-gb-6953

Key Market Segments Covered In Corneal Ulcer Treatment Industry ResearchBy Drug class:AntibioticsAntifungalsAntiviralsCorticosteroidsNSAID’sBy Form:TabletEye Drops/ OintmentsVialsBy Route of Administration:OralTopicalInjectablesBy Indication:Bacterial KeratitisFungal KeratitisViral KeratitisAcanthamoeba KeratitisBy Distribution ChannelHospital PharmaciesRetail PharmaciesDrug StoresOnline PharmaciesBy RegionNorth AmericaLatin AmericaEuropeSouth AsiaEast AsiaOceaniaMiddle East and Africa (MEA)

[sueanoi-the-vet]

granulation tissue in healing corneal ulcer can look really scary.

This dog presented to me after they received treatment for corneal ulcer at a generalist clinic for two weeks. as the left image showed, the red, raising tissue on the eye looks scary. the owner was concerned and decided to get specialist care.

it actually wasn’t a bad thing that these red tissue appear on healing cornea. i adjusted their medication only slightly, and after 10 days the cornea becomes what it looks like on the right image. scar tissue is replacing the granulation. the dog has no pain. This is considered healed. i expect it to become gradually more transparent over a few weeks to months.

the clinic did everything right, they just weren’t able to explain the scary red thing to the owners satisfactory.

dog also has really bad atopic dermatitis. which can very well be the cause of scratch that made the ulcer appear in the first place. we’re taking care of that next.

[risoria]

Anecdotally I can tell you about the saddest dog I have met in my life - and I only worked at a the small animal clinic as a vet for three months in the summer. If I had stayed, I would have met countless others.

A fenchie that was shockingly underweight because he had previously suffered complications after surgery because of his obstructed airways (BOAS). The surgeon had told the owners that the dog couldn’t be put under anasthaesia again because chances were extremely high that he wouldn’t survive it.

He came in because of an corneal injury - this is another thing that is very common with brachy dogs because of their protruding eyes and flat face. They scratch their eyes very easily on sticks, bushes, sharp corners and get deep ulcers on their eyes, simply because of the way their face looks. This is very painful and also often leads to infection which is why antibiotics are most often used - even small scratches can easily worsen to involve more layers of the eye, and go deeper. Surgery is most often needed to remove the dead and damaged layers of the cornea for the healthy tissue to be able to heal - same principle as with skin wounds. Worst case scenario is you have to remove the entire eye in the end if it doesn’t respond to treatment and to relieve the animal of the pain from the eye (enucleation).

This dog got a referral so I have no idea what happened to it of course, I only diagnosed it with the corneal ulcer - it was big and deep and it wasn’t the first time for this dog. And it couldn’t have surgery, because of its BOAS. But the ulcer needs surgery because it’s extremely painful and will most likely get worse and worse. So… :) I hope they managed to treat their dog in some way but… Imagine a scenario where you had to put your dog down because it scratched its eye on a small stick - because it’s bred to not be able to breathe and will die if you put it through surgery. I know that this was an extreme case of course, but it was still because of its airways in the end.

[nerdgirlnarrates]

Now the fluoroquinolones go toe to toe! Both of these medications work by binding the topoisomerase IV/gyrase-DNA complex. Their most unique adverse effect is tendon rupture (avoid in kids and older adults!), and they shouldn't be used in myasthenia gravis patients as they can exacerbate the condition. Both can be used as post-exposure prophylaxis for anthrax. So which fluoroquinolone should move forward?

Ciprofloxacin: Of the fluoroquinolones, cipro has the best activity against both pseudomonas and gram negatives, notably the Enterobacteriaceae. It has a wide variety of uses, and among the most interesting (to me) are treatment of the plague and typhoid fever. On the more mundane side, it's mostly used for GI and GU infections. It can also be formulated as ophthalmic or otic drops for corneal ulcers/conjunctivitis and acute otitis externa, respectively. Beware though: it inhibits cytochrome P450, increasing the risk of drug interactions.

Levofloxacin: levo is considered a respiratory fluoroquinolone since it is mostly (but not exclusively) used for respiratory infections. While levo doesn't cover those fascinating bugs of plague and typhoid fever, it makes up for it by not inhibiting cytochrome P450. As with all fluoroquinolones, it should not be taken with dairy, as it can bind to the calcium and be rendered ineffective.

Vote for the best antibiotic

[careforcritters]

Vet Med in Warrior Cats: Whitecough, Greencough, and Yellowcough

Disclaimer

The two main respiratory infections in the warriors series are whitecough and greencough. Whitecough is less severe and can progress to greencough, which has worse symptoms and a graver prognosis. Vicky Holmes states in the 3rd Erin Hunter chat that whitecough is similar to a cough (likely an upper respiratory infection) and greencough is pneumonia (lower respiratory infection), but the specific diseases that each of these coughs represent is never mentioned. The name “greencough” comes from the green fluid that cats cough up when they are affected, whereas cats with whitecough are stated to cough up clear (serous) fluid. A third respiratory disease, yellow cough, makes an appearance in the A Vision of Shadows series. The disease presents similarly to greencough but does not respond to catmint.

There is no way to tell which pathogens each of these diseases might be caused by because the symptoms of each pathogen are very similar, so they are likely caused by several different pathogens and/or combinations. Feline respiratory disease complex (FRDC) is a major cause of upper respiratory infections in cats and is caused by any of the following pathogens, alone or in combination: feline herpes virus (FVR), feline calicivirus (FCV), mycoplasma felis, and chlamydia felis. Bartonella henselae and Bordetella bronchiseptica can also contribute to symptoms. FVR and FCV specifically cause 80-90% of the respiratory disease that is observed in cats. These pathogens are spread by respiratory droplets, direct contact with infected cats, or contact with fomites (objects that have come into contact with the pathogen). Previously infected cats can carry and spread FVR or FCV without showing clinical signs. Acute signs include fever, sneezing, nasal discharge, conjunctivitis, and rhinitis. “Coughing” is not a symptom of respiratory infections in cats, but it is frequently mentioned in Warriors. Cats cough when affected by a lower respiratory infection, laryngeal infection, allergies, or heartworms, but rarely cough as a result of an upper respiratory infection. Symptoms are often more severe in very old and very young cats, which is consistent with the books since kits and elders die the most often from whitecough or greencough. Cats that have respiratory infections in warriors are often shown to refuse food, which is consistent with findings that sick and/or feverish animals are often anorexic. Calicivirus causes painful lesions in the mouth, which can also contribute to cats refusing to eat. 

FRDC is generally self limiting and resolves itself in 5-10 days in mild cases, but can take up to 6 weeks to resolve completely in more severe cases. Because of this, mild to moderate respiratory infections could be treated with just supportive care. Medicine cats do this by providing food, water, and rest to infected cats, which is why most cases of whitecough or other nondescript respiratory diseases are resolved in the series. The bigger issue is when there are more severe cases or cases that have ocular involvement. 

Ocular involvement can result from almost any respiratory disease causing agent, and can range from discharge to severe conjunctivitis, ulcers, and even globe rupture. Conjunctivitis and other ocular symptoms of respiratory disease are never mentioned in Warriors besides some mild tearing. I will be talking about this issue more in an ocular section later on, as it connects to some broader issues. 

To treat more severe cases of respiratory disease, veterinarians often use antivirals, antibiotics, and/or antifungal depending on the pathogens present. Supportive care should also be provided, in addition to feeding tubes and/or treatment of corneal ulcers if necessary. Medicine cats provide supportive care to their patients by providing them with food, water, and warm, dry bedding. For many cases of respiratory disease, this should be enough to help the cat survive since disease is usually self limiting and will resolve with time. A variety of herbs are used in Warriors to treat respiratory infections, but the most notable is catmint. Catmint is also known as catnip, and it is famously known to have psychological effects on cats by acting first as a stimulant from the smell and then a sedative from ingestion. While its effects mimic pheromones, which can be calming, there is no evidence that catmint can be used to combat respiratory disease. Catnip can also be toxic in large doses, causing nausea and vomiting. Cats also become slowly more resistant to its effects with repeated use. Chickweed and Hawkweed are both less effective treatments for greencough. Chickweed has been shown to have some antimicrobial properties, though it is most effective against salmonella and E.coli, both of which are not respiratory pathogens. Hawkweed has been used in some European countries to ease respiratory disease and asthma symptoms, but there has not been research on this. In Long Shadows, tansy is introduced as a way to prevent whitecough from progressing to greencough. Though tansy has been used for various medical issues in humans, it has never been reported to be used for respiratory disease. Coltsfoot is an herb that eases breathing, so it is commonly used for respiratory distress. Coltsfoot was historically used for coughs and respiratory distress in people, and recent studies have proved its efficacy in reducing lung inflammation. Brighteye and lovage are also mentioned briefly in Mistystar’s Omen as another treatment for coughing. These two herbs have been shown to improve symptoms of respiratory disease and allergies in humans, but have not been researched sufficiently. Lungwort is the herb that is presented to Puddleshine by Starclan to treat the emergent yellowcough epidemic in Shadowclan. Lungwort has been used to ease tuberculosis and asthma in humans, but again, there is no substantial research to back this. In addition, Birchsap is briefly mentioned as another possible treatment for yellowcough, but it’s not seen being used in the books. Birchsap traditionally has various medical and cosmetic uses in some cultures, but no research has been done to prove its efficacy. 

Overall, the Warriors series gives a fairly accurate depiction of respiratory illness while leaving out some crucial details. The omittance of any ocular involvement, especially in young kittens where it is most prevalent, is a large oversight. The description of the disease process is mostly accurate, however coughing is not as common of a symptom as nasal discharge and rhinitis. Cats in feral colonies are often carrying these diseases without actively showing symptoms, which is why bouts of whitecough can appear suddenly in a clan (especially in times of stress and poor nutrition such as leafbare, which would suppress the cat’s immune responses). As far as treatment goes, medicine cats are providing adequate care to most cats but simply taking care of their basic needs. In more severe cases, medicine is needed. While none of the herbs listed can effectively mimic an antibiotic or antiviral, hawkweed, coltsfoot, brighteye, lovage, and lungwort seem like the most accurate treatments for infection used in the books. Coltsfoot specifically has the most evidence for easing respiratory symptoms, and would be beneficial for medicine cats to use in moderate to severe cases of respiratory disease.

Sources:

https://www.merckvetmanual.com/respiratory-system/respiratory-diseases-of-small-animals/feline-respiratory-disease-complex?query=feline%20respiratory%20disease

https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/respiratory-infections 

https://vetmed.tamu.edu/news/pet-talk/feline-fine-the-benefits-of-catnip/ 

https://botanicalinstitute.org/eyebright/

https://botanicalinstitute.org/chickweed/ 

https://www.botanical.com/botanical/mgmh/h/hawmou08.html

https://www.botanical.com/botanical/mgmh/t/tansy-05.html 

https://dsps.lib.uiowa.edu/roots/coltsfoot/ 

https://www.fs.usda.gov/wildflowers/plant-of-the-week/lobaria_pulmonaria.shtml

[moonlight26posts-blog]

In Baltimore County, MD: Small Terrier mix Seeking Rescue

Baltimore County Animal Services is seeking rescue placement for Honey, a 2 year old, 28 pound terrier mix that came to us as a stray. Honey was found to be infested with fleas, causing her hair loss, which treatment has been started for. Honey also has a healed corneal ulcer in her left eye. Honey is pretty standoffish and would benefit from a rescue where a foster can get to know her true personality and find her best home. Honey is not currently available for adoption through us and is only available for a rescue pull. If you are interested in pulling Honey, or have any questions, please let us know!

Thank you,

BCAS Rescue Team

Baltimore County Animal Services

13800 Manor Road

Baldwin, MD 21013

bcasrescue@baltimorecountymd.gov

410-887-7297

Baltimorecountymd.gov/animalservices

To see other animals in need of rescue, visit here: https://www.baltimorecountymd.gov/departments/animal-services/rescue-partners

Adoptable pets: https://www.baltimorecountymd.gov/departments/animal-services/adoption#/

Foster Information: https://www.baltimorecountymd.gov/departments/animal-services/foster/

[mcatmemoranda]

Going through ABFM CKSA questions:

An acute red eye is a common presentation in primary care and it is critical to differentiate serious causes from benign causes. Pain is an important distinguishing feature for the acute red eye. Episcleritis is a self-limited condition that can be idiopathic or associated with autoimmune conditions. It is more common in females and usually presents with mild discomfort and focal hyperemia. Discerning episcleritis from scleritis is important. In general, the inflamed vessels of episcleritis will move with gentle pressure from a cotton-tipped applicator whereas those with scleritis will not, and the pain of scleritis is more intense. The treatment of episcleritis is symptomatic with topical lubricants and oral NSAIDs. If recurrent episodes occur, an autoimmune workup should be considered. Conjunctivitis is typically associated with a discharge that is clear in viral cases and mucopurulent in bacterial cases. Iritis is associated with significant pain, a poorly reactive pupil, diminished vision, and photophobia. This patient does not have changes in visual acuity, photophobia, or severe pain as seen in keratitis, which would also cause an abnormal fluorescein stain showing corneal ulceration.

A Cochrane review reports good evidence that salicylic acid is effective for the treatment of plantar warts. Candida injections may be indicated for warts that are difficult to treat, but they are not considered a first-line treatment. The application of duct tape has not been shown to be more effective than placebo. Manual paring and extraction of plantar warts carries a greater risk for complications and is not necessary for flat, minimally bothersome warts. Laser treatment may be effective, but the cost is not justified as initial therapy in this case.

[sepdet]

so the ulcer on my left eye got worse While I was visiting my parents and I have got my FOURTH $1000 amniotic patch on it trying to heal it (fuck you covid for setting off underlying health issues and essentially triggering the corneal equivalent of the worst damn shingles flareup EVER except it's herpes simplex keratitis not Zoster) anyway i've got all kinds of treatments the point is i'm home and away from several causes of physical and other forms of stress at my parents' which were making it worse so let's see if we can save my vision in that eye.

Right now what I see with the left eye is basically what the world looks like through totally fogged glass on my right eye, which I discovered by blowing on a glass shower door.

I've been dealing with this flareup since August. And it still HURTS.  The only saving grace is that I'm getting used to operating with just One functional eye.

But the strain of dealing with I pain as well as the world being kind of removed because I can't see very well is making it hard for me to string thoughts together, like Trying to take a test when there is someone continually sniffing and refusing to use a Kleenex in the same room with you. (Some people can concentrate through noise/static; I'm one of those people who really has trouble blocking out distractions.)

(I do wish Siri wouldn't capitalize every single time I have to stop and Fix a typo/dictation mistake!)

[lifebiologicsusa]

The Role of Innovative Amniotic Tissue Companies in Modern Medicine

In the ever-evolving field of regenerative medicine, innovative amniotic tissue companies are at the forefront of providing advanced solutions for wound healing, surgical procedures, and pain management. Amniotic tissue, derived from the innermost layer of the placenta, has remarkable healing properties that have made it a game-changer in the medical field. With its unique ability to promote tissue regeneration and reduce inflammation, this natural resource is transforming patient outcomes across the United States.

What Is Amniotic Tissue?

Amniotic tissue consists of the amniotic membrane and fluid that surround and protect a developing fetus during pregnancy. This tissue is rich in growth factors, cytokines, and extracellular matrix components, all of which contribute to its powerful healing capabilities. It also has anti-inflammatory, antimicrobial, and anti-scarring properties, making it an ideal material for a wide range of medical applications.

Amniotic tissue is commonly used in:

Wound Healing: To treat chronic wounds, burns, and diabetic ulcers.

Ophthalmology: For repairing corneal injuries and other eye conditions.

Orthopedics: To manage pain and inflammation in joint and soft tissue injuries.

Surgery: To enhance healing in complex surgical procedures.

The Work of Amniotic Tissue Companies

Amniotic tissue companies are responsible for collecting, processing, and distributing this valuable medical resource. They follow stringent guidelines to ensure the tissue is ethically sourced and processed in a way that preserves its therapeutic properties. Donors are carefully screened, and the tissue is sterilized and cryopreserved to ensure safety and efficacy.

These companies also invest heavily in research and development to expand the applications of amniotic tissue. From developing advanced wound dressings to injectable amniotic products for orthopedic use, their innovations are pushing the boundaries of what regenerative medicine can achieve.

Benefits of Amniotic Tissue in Medicine

The use of amniotic tissue in medical treatments offers numerous benefits:

Accelerated Healing: Amniotic tissue provides an ideal environment for cell growth and tissue regeneration, leading to faster recovery times.

Reduced Inflammation: Its natural anti-inflammatory properties help manage pain and swelling, improving patient comfort.

Lower Risk of Rejection: Since amniotic tissue is immunoprivileged, it minimizes the risk of immune response or rejection.

Versatile Applications: From treating wounds to reducing post-surgical complications, its uses are vast and growing.

Minimized Scarring: Amniotic tissue promotes natural healing processes while reducing the formation of scar tissue.

Innovations Driving the Future

Amniotic tissue companies are continually innovating to improve the accessibility and efficacy of their products. Advances in biotechnology have enabled the creation of injectable amniotic products, which are particularly beneficial in orthopedics for treating joint pain and soft tissue injuries. These products are minimally invasive and deliver targeted healing benefits directly to the affected area.

Furthermore, companies are exploring the potential of amniotic tissue in regenerative therapies for conditions such as arthritis, spinal injuries, and even hair restoration. These cutting-edge applications demonstrate the vast potential of this natural resource in improving patient outcomes.

Challenges and Accessibility

While the benefits of amniotic tissue are undeniable, challenges remain. The cost of these treatments can be prohibitive for some patients, and insurance coverage is not always guaranteed. Additionally, the process of sourcing and processing amniotic tissue requires rigorous adherence to ethical and regulatory standards, which can impact availability.

To address these challenges, leading companies are working to make amniotic tissue products more affordable and accessible. This includes increasing awareness among healthcare providers, partnering with insurance companies, and investing in cost-effective processing methods.

Conclusion

Advanced solutions provided by amniotic tissue companies are revolutionizing healthcare, offering hope and healing to patients across the United States. With their commitment to innovation, safety, and accessibility, companies like Life Biologics are leading the charge in harnessing the power of amniotic tissue for the betterment of modern medicine. As research and technology continue to evolve, the potential for this incredible resource will only grow, ensuring a brighter future for patients in need.

Read More :- https://biologicslife.wixsite.com/lifebiologicsusa/post/exploring-advanced-skin-substitutes-for-wound-healing-1

[sharp-sight92]

What is corneal damage? What are its Causes, Symptoms, and Treatments?

Corneal damage refers to any injury or condition that affects the cornea, the transparent front layer of the eye that covers the iris, pupil and anterior area. A cornea plays a crucial role in focusing vision, and damage to it may impair eyesight.

Types and Causes of Corneal Damage:

Corneal Ulcer

Corneal Abrasion

Keratitis

Corneal Edema

Symptoms of Corneal Damage:

Continues eye pain and discomfort

Blurred vision

Redness and inflammation

Sensitivity to light

Tearing and watery eyes

What are the treatment options available?

Medication

Protective Eyewear

Artificial Tears

Surgery

Rest and care

Sharp Sight has achieved various accreditations and awards which reflect its commitment and quality and excellence in eye care. If you’re suspected of any eye-related problems. Consider Sharp Sight Eye Hospital in Agartala to get the best treatment for your precious eyes.

[daksh-netralaya]

Best Eye Care in Jabalpur: Daksh Netralaya

Comprehensive Eye Care Services

Daksh Netralaya is recognized as the Best Eye Care Center in Jabalpur because of its comprehensive range of services designed to meet all eye health needs:

1. Cataract Surgery

Cataract surgery is one of the most common procedures performed at Daksh Netralaya, where the latest techniques and advanced technology are used to restore vision. Renowned for offering the Best Cataract Surgery in Jabalpur, the hospital’s ophthalmologists use precise surgical methods to ensure minimal recovery time and maximum vision improvement for their patients.

2. Retina Treatments

Retinal disorders can be complex and require specialized treatment. Daksh Netralaya is reputed as the Best Retina Treatment in Jabalpur, providing expert care for conditions like macular degeneration, diabetic retinopathy, and retinal detachments. As the Best Retina Specialist Hospital in Jabalpur, the hospital employs advanced diagnostic tools and treatments to effectively address these serious conditions.

3. Cornea Treatments

Corneal diseases can significantly impact vision if left untreated. Daksh Netralaya, known for the Best Cornea Treatment in Jabalpur, offers solutions for conditions such as keratoconus, corneal ulcers, and scarring. The center’s advanced corneal transplant and other surgical options have helped many patients regain clarity in their vision.

4. Ophthalmology Services

Daksh Netralaya’s ophthalmologists are highly skilled professionals recognized as some of the Best Eye Doctors in Jabalpur. They provide a wide range of services, from routine eye check-ups to complex surgeries. As the Best Ophthalmologist in Jabalpur, the team at Daksh Netralaya combines knowledge with compassion, ensuring every patient receives the highest standard of care.

Cutting-Edge Technology and Facilities

Daksh Netralaya is equipped with advanced diagnostic and surgical equipment, including OCT, fundus photography, and lasers. The hospital is committed to using these technologies to deliver precise diagnoses and treatments, establishing itself as a trusted Eye Care Center in Jabalpur.

Why Choose Daksh Netralaya?

Experienced Team of Specialists: Daksh Netralaya has a team of Eye Specialists in Jabalpur who are highly qualified and experienced in various fields of ophthalmology.

Patient-Centered Care: The hospital prioritizes the patient’s needs, providing personalized treatment plans and comprehensive follow-up care.

Advanced Procedures: From cataract surgery to corneal transplants, Daksh Netralaya offers cutting-edge procedures to treat complex eye conditions.

Affordable and Accessible: The hospital aims to make quality eye care accessible to everyone in Jabalpur by offering affordable treatment options.

FAQs about Daksh Netralaya

1. Who is the best eye doctor in Jabalpur?

Daksh Netralaya is home to some of the Best Eye Doctors in Jabalpur. The specialists here are experienced in treating a wide range of eye conditions with a focus on patient comfort and recovery.

2. What is the cost of cataract surgery at Daksh Netralaya?

The cost of Best Cataract Surgery in Jabalpur at Daksh Netralaya depends on the type of lens implant chosen. They provide affordable packages tailored to suit individual needs.

3. How can I book an appointment with an eye specialist in Jabalpur?

Appointments with Daksh Netralaya’s Eye Specialists in Jabalpur can be scheduled by calling the hospital directly or through their website for added convenience.

4. Is retina treatment available at Daksh Netralaya?

Yes, Daksh Netralaya offers the Best Retina Treatment in Jabalpur, catering to various retinal issues such as diabetic retinopathy and macular degeneration.

5. Are there any specialized cornea treatments available?

Daksh Netralaya provides the Best Cornea Treatment in Jabalpur for conditions like keratoconus and corneal scarring. Advanced corneal transplants are also available when necessary.

[sueanoi-the-vet]

melting corneal ulcer.

this is a sign there is bacterial activity due to collagenase destroying the cornea collagen layers.

i always recommend bacterial culture for best treatment result. meanwhile, treatment should at least include antibiotic eye drop and anticollagenese drop (serum or acetylcysteine). preferable if analgesia (atropine) and artificial tear are included. always use cone collar to prevent self harm.

this cat got better and eye sight is preserved in a few weeks.

[maxivision123]

Corneal Ulcers: Protect Your Vision with Expert Care

Your eyes are a delicate window to the world, and maintaining their health is essential for a fulfilling life. Corneal ulcers are one of the most serious conditions that can threaten your vision if left untreated. By understanding the symptoms, causes, and effective corneal ulcer treatment options, you can take the right steps to safeguard your eyes.

What Are Corneal Ulcers?

A corneal ulcer is an open sore on the cornea, the clear, dome-shaped surface covering the front of your eye. This condition often results from infections or injuries to the cornea, leading to inflammation, pain, and potential vision loss if untreated.

Common Causes of Corneal Ulcers

Corneal ulcers can occur due to a variety of reasons:

Infections: Bacterial, viral, fungal, or parasitic infections are the most common causes.

Injuries: A scratch or trauma to the cornea can lead to an ulcer if the wound becomes infected.

Contact Lens Use: Poor hygiene or overuse of contact lenses increases the risk of corneal infections.

Dry Eye Syndrome: Insufficient tears can leave the cornea vulnerable to damage.

Immune Disorders: Autoimmune conditions may predispose individuals to corneal ulcers.

Symptoms of Corneal Ulcers

Early detection is key to effective corneal ulcer treatment. Be alert for these symptoms:

Persistent eye pain or discomfort.

Redness and swelling around the eye.

Sensitivity to light (photophobia).

Blurred or decreased vision.

A white or gray spot visible on the cornea.

Watery eyes or discharge from the affected eye.

Why Early Treatment Is Essential

Corneal ulcers can lead to severe complications, including permanent vision loss or blindness, if not addressed promptly. Seeking treatment from an experienced ophthalmologist ensures the best corneal ulcer treatment and recovery outcomes.

Diagnosis and Evaluation

When you visit an eye specialist, they will perform a detailed examination to diagnose a corneal ulcer. This typically includes:

Slit-Lamp Examination: To closely inspect the cornea for ulcers or abnormalities.

Fluorescein Staining: A dye test to identify corneal damage.

Culture Tests: To determine the exact cause of infection, guiding targeted treatment.

Treatment Options for Corneal Ulcers

Treatment depends on the severity and underlying cause of the ulcer. Here are the primary options:

Antibiotics and Antifungals: For bacterial or fungal infections, specialists prescribe medicated eye drops to eliminate the infection and prevent further damage.

Antiviral Medications: If the ulcer is caused by a virus, such as herpes simplex, antiviral drugs are essential.

Pain Management: Lubricating eye drops or ointments may be recommended to ease discomfort.

Protective Measures: Your doctor might advise you to wear an eye patch to shield the cornea as it heals.

Surgical Intervention: In severe cases, a corneal transplant may be required to restore vision.

By seeking the best corneal ulcer treatment from a trusted eye hospital, patients can experience a full recovery and avoid long-term complications.

Prevention Is Better Than Cure

Preventing corneal ulcers is simpler than treating them. Follow these tips to protect your eyes:

Maintain strict hygiene when handling contact lenses.

Avoid rubbing your eyes, especially if they are irritated or injured.

Seek prompt medical attention for any eye infection or trauma.

Use protective eyewear during activities that pose a risk of injury.

Treat underlying conditions like dry eyes or blepharitis proactively.

Choosing the Right Eye Hospital for Corneal Ulcer Treatment

The quality of care you receive plays a significant role in your recovery. Look for an eye hospital that offers:

Specialized Expertise: Experienced ophthalmologists who are well-versed in managing corneal ulcers.

Advanced Technology: Access to the latest diagnostic tools and treatment options.

Comprehensive Care: A team that prioritizes personalized care for every patient.

Maxi Vision, a super speciality eye hospital, stands out as a trusted provider of exceptional care. Their commitment to patient well-being, combined with state-of-the-art facilities, ensures that every individual receives the best corneal ulcer treatment tailored to their needs.

When to Seek Medical Help

Do not delay if you experience symptoms of a corneal ulcer. Early intervention significantly improves the likelihood of a positive outcome. Whether it’s mild discomfort or noticeable vision changes, consulting an expert can make all the difference.

Conclusion

Corneal ulcers are a serious eye condition that demands prompt attention and expert care. By understanding the causes, symptoms, and treatment options, you can protect your eyes from potential damage and ensure lasting eye health. Trust Maxi Vision, a super speciality eye hospital, to provide the best corneal ulcer treatment with compassion and expertise. Their focus on advanced care and patient satisfaction makes them the ideal choice for safeguarding your vision. Don't wait—your eyes deserve the very best.

[jcsmicasereports]

Basal cell carcinoma resection in an Ecuadorian patient with Gorlin-Goltz syndrome by Andrea Villarreal-Juris in Journal of Clinical Case Reports Medical Images and Health Sciences

Abstract

Gorlin-Goltz syndrome is an inherited dominant autosomal disorder characterized by a predisposition to numerous cancers. The clinical-pathological findings of this syndrome are very diverse. The objective of this report is to present an Ecuadorian patient with Gorlin-Goltz syndrome who underwent surgical resection of basal cell carcinoma compatible lesions.

Conclusion: Gorlin-Goltz syndrome encompasses a variety of clinical signs and symptoms, including important oral manifestations and skin lesions that must be recognized to achieve an early specialty referral, thus reducing the risk of malignancy through a multidisciplinary treatment.

Keywords: Basal Cell Nevus Syndrome, Gorlin-Goltz syndrome, Carcinoma, Basal Cell

Introduction

Gorlin-Goltz (G-G) syndrome or nevoid basal cell carcinoma syndrome (NBCCS) is a dominant autosomal genetic disorder with high penetrance. Fifty percent of patients who suffer from it have a mutation in the long arm of chromosome 9q22.3 in the area of the PTCH gene (protein patched homolog) (1–3), a homologue of the Drosophila patched gene (PTC), which encodes a transmembrane receptor protein (4). This protein binds to a soluble factor of the hedgehog family (Hh), thus activating the Smo (smoothened) receptor, which unblocks the transcription of several growth factors. Therefore, the PTCH gene is an oncosuppressor that is part of the Sonic Hedgehog Homolog (Shh) signaling pathway and is crucial in embryonic development, cell division control, and tumor growth (5).

Its approximate prevalence is 1 in 57000 to 1 in 256000 and the ratio of males to females is 1:1 (6). Binkley and Johnson reported this syndrome for the first time in 1951 (7), then, in 1960, Gorlin and Goltz described the association between multiple basal cell carcinoma, odontogenic keratocysts (OKC) and bifid ribs, which account for the characteristic triad (8). In 1977, Rayner et al. added additional features, including calcification of the falx cerebri and palmar/plantar fossae (9).

According to the criteria of Kimonis et al., the diagnosis of G-G syndrome requires the coexistence of at least two major criteria or one major and two minor (10).

The characteristic that is usually diagnosed first is OKC, because it can be detected during the first decade of life and appears in almost 80% of G-G syndromes.

Other manifestations include palmar and plantar ulcers that appear as shallow pits, caused by partial or complete absence of the corneal layer, which can also appear along the sides of the hands and fingers and even on the tongue; spina bifida (10,11); medulloblastoma (can be an epiphenomenon of G-G, especially in children who are ≤5years-old) (12); cardiac tumors, including fibromas and ventricular histiocytomas, usually congenital (13); hypertelorism, congenital cataract, nystagmus, coloboma and strabismus (14); and ameloblastoma (extremely rare) (15,16).

Early diagnosis of G-G syndrome and its subsequent treatment are very important due to neoplasm susceptibility (2).

The case of a patient with a previous diagnosis of Gorlin-Goltz syndrome who presented multiple lesions compatible with basal cell carcinoma is presented below.

Case Report

A 35-year-old male, living in Quito, Ecuador, without allergies; no history of tobacco or alcohol intake. His mother and his brother presented Gorlin-Goltz syndrome (G-G).

The patient presents hereditary and congenital G-G syndrome (multifocal basal cell carcinoma and maxillary keratocysts), whose manifestations began at the age of 22. He underwent surgery for bilateral keratocysts at the age of 25, and multiple biopsies of the upper left eyelid were taken since 2012. In August 2015, with a positive tumoral activity biopsy report, a wide resection involving 60% of the left upper eyelid plus flap reconstruction was performed.

Physical examination revealed multiple surgical scars on the left upper eyelid with tumoral activity on the eyelid margin, as well as on the outer third of the ipsilateral lower eyelid and on the right side.

In October, a wide resection of the left upper and lower eyelid was planned, plus reconstruction and transoperative study, which are performed without complications.

Subsequently, the patient attended scheduled control, reporting the presence of a left superciliary nodular lesion. Physical examination revealed multiple lesions located in the left superciliary region, left helix, concha, and antihelix, in the inner corner of the left lower eyelid, in the left parieto-temporal and occipito-temporal regions, and other small bilateral genian lesions. There were no alterations in the flap. Left external campimetry was limited. It was decided to perform a facial bone and skull simple and contrasted tomography (CT) and laboratory tests.

Then, resection of the previously mentioned lesions and resection of the lower eyelid with transoperative study, shield-type incision and external canthoplasty of the lower left eyelid was planned. A plastic surgeon was included in the surgical team.

Altogether, 9 skin lesions located in the left superciliary, left frontal, interparietooccipital, posterior occipital, auricular, and left retroauricular regions were resected, which were positive for basal cell carcinoma.

In the subsequent control, the patient's campimetry showed improvement.

DISCUSSION

Reports about Gorlin-Goltz syndrome are scarce in the literature (17). The rarity and phenotypic variability of this syndrome causes a delay in its diagnosis. Syndromicassociated keratocystic odontogenic tumors are often treated in the same way as nonsyndromic cases (18) and associated systemic signs can easily be missed due to lack of understanding of the syndrome. In addition, their characteristics vary globally, so doctors and even dentists must identify them in a timely manner, considering those that are more prevalent in their population or similar populations (19,20).

The pathogenesis of basal cell carcinoma (BCC) is thought to involve increased sensitivity to ultraviolet light and to involve ineffective mechanisms that repair UVinduced DNA damage. In any case, this theory is not accepted by all authors since these lesions can also appear in areas that have not been exposed to sunlight. Especially in children, patients with G-G syndrome who undergo radiotherapy for other cancers have shown to be at increased risk of radiation-induced BCC (21).

In 50% of patients with G-G syndrome, jaw keratocysts appear, characterized by a thin surrounding layer of epithelial cells, which tend to reappear locally after excision in 6 to 60% of cases, therefore, the indication for surgery should be carefully considered, also due to the possibility of intensive clinical and instrumental monitoring (22).

In recent years, new drugs have been developed to inhibit certain components of the sonic hedgehog signaling pathway. In 2013, the FDA approved vismodegib, the first small molecule to target this pathway (11). Although these agents seem promising options for patients with G-G syndrome, their efficacy is limited by adverse effects and the development of resistance (23). Logically, a more aggressive approach is necessary if basal cell carcinoma is suspected; subsequently, depending on the lesion site and the surgery type, a reconstruction can be performed, as in the case presented in this article (24,25).

CONCLUSION

Gorlin-Goltz syndrome encompasses a variety of clinical signs and symptoms, including important oral manifestations and skin lesions that must be recognized to achieve early referral to a specialty, thus reducing the risk of malignancy through multidisciplinary treatment.

Ethical responsibilities

In this case report, the informed consent of the patient was obtained. Its elaboration and all the inherent details were based on the Declaration of Helsinki.

[ramahospital]

Corneal Diseases: Understanding and Managing Vision Impairment

The cornea is the transparent, dome-shaped layer covering the front of the eye. It plays a crucial role in focusing light on the retina, enabling clear vision. Any disease or damage to the cornea can disrupt this process, leading to discomfort, impaired vision, or even blindness. Corneal diseases encompass a range of conditions that affect the cornea's structure, transparency, and function.

Common Corneal Diseases

Keratitis: Inflammation of the cornea, often caused by bacterial, viral, or fungal infections. Non-infectious keratitis can result from prolonged contact lens use or eye injuries.

Corneal Dystrophies: A group of genetic disorders where abnormal material builds up in the cornea, affecting its transparency. Examples include Fuchs' dystrophy and lattice dystrophy.

Corneal Ulcers: Open sores on the cornea caused by infections, trauma, or severe dry eye. These ulcers can cause redness, pain, and blurred vision.

Keratoconus: A progressive condition where the cornea thins and bulges into a cone-like shape, distorting vision.

Dry Eye Syndrome: While not exclusively a corneal disease, dry eyes can damage the cornea over time, leading to discomfort and vision issues.

Corneal Scarring: Caused by trauma, infections, or surgery, scarring can obstruct light from entering the eye properly, leading to visual impairment.

If you suspect any issues with your cornea, seeking treatment at an Eye Specialist Hospital in Mandhana can ensure prompt diagnosis and effective care.

Symptoms of Corneal Diseases

Symptoms of corneal diseases may vary depending on the condition but commonly include:

Blurred or distorted vision

Redness and inflammation

Eye pain or discomfort

Sensitivity to light (photophobia)

Excessive tearing or dryness

Feeling of a foreign object in the eye

These symptoms should not be ignored, as early intervention can prevent further complications and preserve vision.

Causes and Risk Factors

Corneal diseases can result from various factors, including:

Infections: Bacterial, viral, or fungal pathogens can invade the cornea and cause inflammation.

Injuries: Scratches, chemical burns, or foreign objects in the eye can damage the cornea.

Genetics: Certain corneal dystrophies are inherited conditions.

Environmental Factors: Prolonged exposure to UV rays, pollutants, or dry climates can harm the cornea.

Medical Conditions: Autoimmune diseases and prolonged use of contact lenses increase the risk of corneal problems.

Diagnosis and Treatment

A comprehensive eye examination by specialists is essential for diagnosing corneal diseases. Tests like corneal topography, slit-lamp examination, and pachymetry help assess the cornea's structure and function.

Treatment options include:

Medications: Antibiotics, antifungals, or antivirals to treat infections, and lubricating eye drops for dry eye.

Specialized Contact Lenses: Scleral lenses or rigid gas-permeable lenses can correct vision in keratoconus patients.

Surgical Procedures:

Corneal Transplant (Keratoplasty): Replaces damaged corneal tissue with healthy donor tissue.

Collagen Cross-Linking: Strengthens the cornea in early stages of keratoconus.

Phototherapeutic Keratectomy (PTK): Removes damaged corneal layers.

An Eye Specialist Hospital in Mandhana is equipped with advanced diagnostic tools and experienced professionals to provide personalized care for corneal conditions.

Prevention and Care

To reduce the risk of corneal diseases:

Practice proper hygiene, especially if using contact lenses.

Wear protective eyewear to prevent injuries.

Avoid touching your eyes with unclean hands.

Use lubricating eye drops if you experience dryness.

Conclusion

Corneal diseases can significantly affect the quality of life if left untreated. Early diagnosis, preventive measures, and timely treatment are essential for preserving vision. By consulting experts at a trusted Eye Specialist Hospital in Mandhana, individuals can receive the care and guidance needed to safeguard their eye health and maintain clear vision for years to come.

[drnehakamalrathi]

Can LASIK Surgery Be Performed on Individuals with a History of Corneal Ulcers?

If you've been considering LASIK treatment in Bangalore, but have a history of corneal ulcers, you might be wondering if this vision correction procedure is still an option for you. As an eye specialist, I frequently encounter patients who are concerned about whether their previous eye conditions could affect their eligibility for LASIK surgery. In this article, I'll address the key questions around LASIK for patients with a history of corneal ulcers, helping you understand what factors come into play when evaluating if you're a suitable candidate.

Understanding LASIK and Corneal Ulcers

Before diving into whether LASIK is a viable option for those with a history of corneal ulcers, it's important to understand what these terms mean. LASIK (Laser-Assisted in Situ Keratomileusis) is a popular laser eye surgery that corrects vision by reshaping the cornea, allowing light to focus correctly on the retina. This results in clear vision, often eliminating the need for glasses or contact lenses.

On the other hand, a corneal ulcer is an open sore on the cornea, typically caused by an infection, injury, or underlying eye condition. It can lead to symptoms like redness, pain, blurred vision, and sensitivity to light. Given the cornea's critical role in vision, any damage to it, including past ulcers, raises concerns about undergoing LASIK.

Can LASIK Be Safe for Patients with a History of Corneal Ulcers?

The short answer is: it depends. While a history of corneal ulcers doesn't automatically disqualify you from getting LASIK, it requires a thorough evaluation by an eye specialist. The health and stability of your cornea will be the main deciding factors. Here’s what I, as an eye doctor, would consider before recommending LASIK:

Corneal Stability: If the ulcer has completely healed and the cornea has returned to a stable, healthy condition, you may still be eligible for LASIK. However, if there are any lingering scars or thinning of the cornea, this could pose a risk.

No Active Infections: You must be free of any active infections or inflammation in your eyes. Any ongoing issues could complicate the healing process after LASIK.

Corneal Thickness: During the pre-LASIK evaluation, we use tests to measure corneal thickness. If the previous ulcer has caused significant thinning, it might affect your suitability for LASIK, as a certain corneal thickness is required for the procedure.

Factors That Determine Eligibility for LASIK

When assessing if LASIK is suitable for someone with a history of corneal ulcers, several factors come into play:

Complete Healing of the Ulcer: It's crucial that the ulcer has fully healed without any residual inflammation or infection. A healed ulcer with minimal or no scarring increases the chances of being a candidate for LASIK.

Location of the Scar: If there is a scar left from the ulcer, its location on the cornea matters. Scars in the central part of the cornea can affect vision and may complicate the LASIK procedure. Peripheral scars, however, might not pose as much of a problem.

Ocular Surface Health: Dry eyes are a common issue after LASIK. Patients with a history of corneal ulcers may already have compromised ocular surfaces, which could increase the risk of post-LASIK dry eye syndrome. As part of your evaluation, we'll assess the overall health of your ocular surface.

Point-by-Point Guide: Key Assessments Before LASIK Surgery

When considering LASIK after a history of corneal ulcers, here's a breakdown of the assessments typically performed:

Comprehensive Eye Examination: A thorough eye check-up is crucial to evaluate your overall eye health, including the cornea.

Corneal Topography: This test maps out the shape of your cornea, helping us detect any irregularities caused by past ulcers.

Pachymetry: This measures the thickness of your cornea to ensure there’s enough tissue for safe LASIK reshaping.

Tear Film Evaluation: Dry eyes can be a concern, especially if your eyes were affected by the previous ulcer. We'll assess your tear film to prevent complications after LASIK.

Scarring Analysis: Using advanced imaging, we'll check if any corneal scars could interfere with the LASIK procedure.

What Are the Alternatives If LASIK Isn’t an Option?

If you’re not a suitable candidate for LASIK due to corneal damage from past ulcers, don’t worry—there are other vision correction options available:

PRK (Photorefractive Keratectomy): Unlike LASIK, PRK doesn’t involve creating a corneal flap, which might be safer for patients with corneal scars. It’s often recommended for those with thinner corneas.

ICL (Implantable Collamer Lens): This is a type of implant that can correct vision without altering the cornea’s shape. It’s a great option for those who cannot undergo LASIK.

Advanced Surface Ablation: Similar to PRK, this procedure works directly on the cornea’s surface, which can be beneficial for those with corneal irregularities.

The Importance of a Personalized Evaluation

Every patient’s eye health is unique, especially if you’ve had a corneal ulcer in the past. As your eye doctor, my goal is to provide a personalized evaluation to determine the safest and most effective vision correction option for you. At The Eye Foundation, we use state-of-the-art diagnostic tools to ensure you receive the best care.

If you’ve been considering LASIK treatment in Bangalore but have concerns due to a history of corneal ulcers, I encourage you to schedule a consultation. During your visit, we'll thoroughly assess your eye health and discuss whether LASIK or an alternative vision correction procedure is best for you.

As Dr. Neha Kamal Rathi at The Eye Foundation, I’m dedicated to helping my patients achieve their best possible vision. Don’t let past eye conditions hold you back from the clarity you deserve. Book your appointment today and take the first step toward a clearer, brighter future!

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