#Autism Spectrum Disorder Treatment Market Revenue
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Autism Spectrum Disorder Treatment Market Trends Analysis Report By Treatment Type, Application, Distribution Channel, Region And Forecast To 2030: Grand View Research Inc.
San Francisco, 8 Aug 2023: The Report Autism Spectrum Disorder Treatment Market Size, Share & Trends Analysis Report By Treatment Type (Stimulants, Antipsychotic Drugs), By Application, By Distribution Channel, By Region, And Segment Forecasts, 2023 – 2030 The global autism spectrum disorder treatment market size is expected to reach USD 3.28 billion by 2030, according to a new report by Grand…
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#Autism Spectrum Disorder Treatment Market#Autism Spectrum Disorder Treatment Market 2030#Autism Spectrum Disorder Treatment Market Revenue
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Autism Spectrum Disorder Treatment Market Revenue, Segments, Analysis and Forecasts 2032
Autism Spectrum Disorder (ASD) affects millions of individuals worldwide, influencing social interaction, communication, and behavior. Effective treatment for ASD combines behavioral therapies, medication, and support services tailored to individual needs, helping individuals with ASD lead fulfilling lives. With increasing awareness and scientific understanding, advancements in ASD treatment are focusing on innovative approaches that foster independence, improve quality of life, and support both individuals and their families.
The Autism Spectrum Disorder Treatment Market size was valued at USD 2.16 Billion in 2023 and is expected to reach USD 3.71 Billion By 2032 and grow at a CAGR of 6.2% over the forecast period of 2024-2032.
Future Scope
The future of ASD treatment is geared towards personalized and technology-driven therapies that address the unique needs of each individual. Integrating genetic research with therapeutic interventions is expected to enhance treatment precision, while AI-powered platforms hold promise for improving early detection and intervention. Further, wearable devices and mobile applications are being developed to support real-time monitoring and management, providing caregivers and therapists with valuable insights into behavioral patterns.
Emerging Trends
Emerging trends in ASD treatment include the use of virtual reality (VR) and augmented reality (AR) technologies to create immersive environments that help improve social and communication skills. Machine learning algorithms are also aiding in the identification of ASD at earlier stages, enabling earlier intervention. In addition, dietary and microbiome-based therapies are gaining attention for their potential to alleviate certain ASD symptoms, while robotics is being explored to support social skill development in children.
Applications
ASD treatments are applied across various domains of support, including behavioral therapies like Applied Behavior Analysis (ABA), speech and occupational therapies, and social skills training. These treatments are customized to improve communication abilities, reduce problematic behaviors, and enhance social engagement. Pharmacological interventions are sometimes used to manage symptoms such as anxiety, hyperactivity, and irritability, providing additional support alongside behavioral therapies.
Key Points
ASD treatment focuses on improving communication, social interaction, and quality of life.
Emerging technologies like VR, AI, and machine learning support early detection and intervention.
Personalized therapy approaches, including microbiome and dietary adjustments, are being explored.
Robotics and virtual environments are enhancing social skill development in ASD treatment.
Conclusion
Innovative approaches in ASD treatment are transforming the lives of individuals on the autism spectrum, providing them with new opportunities for independence and improved social interaction. As advancements in technology and personalized medicine continue to evolve, ASD treatment is expected to offer even more targeted and effective solutions, empowering individuals with ASD to reach their full potential. By enhancing support systems and exploring new therapeutic methods, the future of ASD treatment looks brighter than ever.
Read More Details: https://www.snsinsider.com/reports/autism-spectrum-disorder-treatment-market-3024
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#Autism Spectrum Disorder Treatment Market#Autism Spectrum Disorder Treatment Market Size#Autism Spectrum Disorder Treatment Market Share#Autism Spectrum Disorder Treatment Market Growth#Autism Spectrum Disorder Treatment Market Trends
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The Rise of Speech Therapy: Exploring Market Size and Growth Potential
The global Speech Therapy Market Revenue, valued at USD 11.13 billion in 2023, is anticipated to witness significant growth, reaching USD 18.19 billion by 2032. This expansion reflects a compound annual growth rate (CAGR) of 5.64% over the forecast period from 2024 to 2032. The rising demand for speech therapy services is driven by increasing awareness of speech and communication disorders, coupled with the growing need for early diagnosis and intervention.
Market Dynamics and Growth Drivers
Speech therapy involves the assessment and treatment of speech, language, voice, and communication disorders. It plays a crucial role in improving communication skills and enhancing the quality of life for individuals with speech impairments. The market's growth is largely fueled by the increasing prevalence of speech-related disorders, such as stuttering, autism spectrum disorders, dysarthria, and aphasia, among both children and adults.
Advancements in technology have also led to the development of innovative speech therapy solutions, including mobile apps, teletherapy platforms, and speech-generating devices. These technologies have made speech therapy more accessible and effective, especially for individuals in remote locations or those with limited access to traditional therapy services. As a result, the adoption of digital speech therapy solutions is expected to rise, contributing to market growth.
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Key Market Trends
One of the key trends in the Speech Therapy Market is the increasing focus on early intervention programs. Early diagnosis and treatment of speech disorders can lead to better outcomes, especially in children. Consequently, there is a growing emphasis on screening and early intervention programs in schools, healthcare facilities, and community centers. This trend is expected to drive the demand for speech therapy services over the coming years.
Another notable trend is the expansion of teletherapy services. The COVID-19 pandemic accelerated the adoption of telehealth across the healthcare sector, and speech therapy was no exception. Teletherapy has enabled speech-language pathologists (SLPs) to provide services remotely, making therapy sessions more convenient and accessible for patients. This approach has proven to be effective, especially for children and individuals with busy schedules, and is likely to remain a popular option even after the pandemic.
Moreover, technological advancements have led to the development of speech therapy apps and software that offer interactive exercises, games, and activities to help improve speech and communication skills. These digital tools are designed to engage users and make therapy sessions more enjoyable, thereby improving treatment adherence and outcomes. As a result, the integration of digital solutions into speech therapy is becoming increasingly common.
Regional Insights
North America dominated the Speech Therapy Market in 2023, holding the largest market share. The region's growth can be attributed to the high prevalence of speech and language disorders, advanced healthcare infrastructure, and the presence of skilled speech-language pathologists. Additionally, the U.S. government's initiatives to improve healthcare access and early childhood development programs have contributed to the increased demand for speech therapy services.
The Asia-Pacific region is expected to witness the highest growth rate during the forecast period. Factors such as the rising awareness of speech disorders, increasing healthcare expenditure, and growing adoption of digital health solutions are driving market growth in countries like China, India, and Japan. Furthermore, the expanding healthcare infrastructure and initiatives to improve early diagnosis and intervention are contributing to the market’s expansion in this region.
Key Players in the Market
The Speech Therapy Market features several key players, including Speech-Language and Hearing Associates, Lingraphica, Speech Therapy Centres of Canada Ltd., Smart Speech Therapy LLC, and TinyEYE Therapy Services. These companies are focusing on expanding their service offerings, developing innovative digital solutions, and forming strategic partnerships to strengthen their market presence. Continuous investment in research and development is also helping these companies introduce new and effective therapy solutions to meet the evolving needs of patients.
Conclusion
The global Speech Therapy Market is poised for substantial growth over the next decade, driven by increasing awareness of speech disorders, technological advancements, and the growing adoption of digital health solutions. As the demand for accessible and effective speech therapy services continues to rise, market players are expected to explore new opportunities and expand their reach, offering significant benefits to patients worldwide.
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Pediatric Healthcare Market Forecast Report 2021 – 2030: Top Key Players Analysis
Pediatric healthcare is defined as a branch of medicine that deals with the treatment of child-related diseases that affect the infants and children most. Due to lower immunity, many children suffer from gastrointestinal diseases, respiratory diseases, and other chronic diseases. Pediatric healthcare provides comprehensive care to all patients from birth to eighteen years of age. It manages the physical health, behavior-related health, and mental health of the children. In a recent study by Hiroshima University it was reported that Hepatoblastoma (HB) was the most common liver cancer in children. It mainly affected the children up to three years old.
In terms of revenue, pediatric healthcare market was valued at more than US$ 90 Bn in 2020 and is estimated to register a CAGR of 5.1% over the forecast period (2021 – 2029).
Some key players in the global pediatric healthcare market are Allergan, Aveanna Healthcare LLC., BAYADA Home Health Care, Boehringer Ingelheim International GmbH, Boston Scientific Corporation, Cardinal Health, Eisai Co. Ltd., Epic Health Services, GE Healthcare (GENERAL ELECTRIC COMPANY), Gilead Sciences Inc., GlaxoSmithKline PLC, Koninklijke Philips N.V., Maksun Biotech Pvt. Ltd., Merck & Co. Inc., PAX HEALTHCARE, Pediapharm, Sanofi, Siemens Medical Solutions USA Inc., and Stryker amongst others.
Read the Full Article @ https://www.industryglobalnews24.com/global-pediatric-healthcare-market-is-estimated-to-witness-a-growth-rate-of-51-over-the-forecast-period
Increasing prevalence of diseases among neonates and infants is a major factor driving the global pediatric healthcare market growth. In 2010, more than 8% of children had a health condition that interfered with daily activities. Compared to last 50 years, this percentage symbolized an increase of more than 400%. 14% to 16% of this 400% increase came from an increase from four classes of more common conditions that were usually less complex and they did not have substantial mortality associated with them. These conditions included asthma, obesity, mental health conditions, and neurodevelopmental disorders. In the 21st century, the rates of asthma and obesity stabilized. However, rate of other conditions, such as autism spectrum disorders and attention deficit hyperactivity disorder (ADHD) kept on increasing, along with the rates of diagnosis. This resulted into better awareness of the conditions. Due to better awareness and more diagnosis, the demand for pediatric healthcare has increased all over the world, contributing to more investment in this market and leading to global pediatric healthcare market growth.
In September 2021, American Heart Association (AHA) highlighted hypertension as the major cause of increased mortality, cardiovascular disease, and chronic kidney disease. Increased body weight and obesity, occurring with hypertension, were identified as major risk factors causing chronic diseases. Hence, pediatric healthcare for treating and preventing hypertension-related obesity showcases huge potential for market growth. The spread of China-originated coronavirus pandemic significantly increased the demand for home healthcare services to children who maybe suffering from single or multiple chronic conditions. However, as physician visits were restricted during the COVID-19 pandemic, due to all countries implementing and enforcing lockdowns, the role of telemedicine in pediatric healthcare increased. The technologies which are a part of telemedicine introduced virtual visits for patient care. In December 2020, a New York-based home care agency, St. Mary's Home Care, launched a virtual service platform for patient engagement. Due to COVID-19 pandemic, the role of home healthcare increased in global pediatric healthcare market. Many healthcare facilities started to provide medications at home so that patients' frequency of visiting hospitals would reduce and the spread of virus would get prevented. Development of life-saving devices for children is anticipated to proliferate the growth of global pediatric healthcare market over the future years. Due to technological advancement in medical sector, there are bespoke mission critical systems in technologically advanced countries like Australia that are supporting largest organizations with technology architecture and solutions that play an important role within medical sector. These devices can be integrated with other software-based medical devices and can be useful for customized treatment for those chronic diseases which most people suffer from during childhood. In 2013, there were 75 million children in USA who at that time, accounted for 24% of total US population (315 million). In September 2021, the Penn State Health Life Lion Critical Care Transport fleet added new pediatric ambulance that was equipped with latest technology. The new life-saving ambulance features of this ambulance included several pieces of specialty equipment, such as a transport isolette for infants, a stronger oxygen system, and a ventilator.
Demand and Market for Devices to rapidly grow over the Forecast Period (2021 – 2029) due to Technological Advancement in the Medical Sector
According to Absolute Market Insights report, devices/equipment segment will remain the fastest growing segment during forecast period in the global pediatric healthcare market. Cardiology devices are long, thin, flexible tubes that are threaded into a heart or other blood vessel. The purpose of threading activities is to open narrowed or blocked areas so that the blood flow to the heart can be improved, along with chest pain reduction. These devices are commonly used for the treatment of heart attacks. In September 2021, Children's Hospital Los Angeles (CHLA) inaugurated new heart institute faculty. Increased advancements in medical devices and equipment, specifically for pediatric patients, is anticipated to further the segment’s growth in the global market over the forecast period.
Rising volume of pediatric patient cases kept the market strong in the North America Region in 2020
According to various online reports, rising volume of pediatric cases was a leading cause of for the necessity of pediatric healthcare in 2020. North America region was the largest regional market in 2020 due to presence of key market players, rising volume of pediatric cases, rise in government initiatives to create awareness in people for pediatric treatments as well as disorders, and availability of advanced medical sector. In North America, especially in USA, the volume of children suffering from autism, cerebral palsy, muscular atrophy, and respiratory disorders is rapidly increasing. According to the 2018 statistics from American Academy of Allergy, Asthma & Immunology, more than 40% of children in USA had allergies and due to this, which contributed towards the high demand for pediatric healthcare in the country. Other factors contributing to the market in this region include increasing investment in R&D in medical sector, high adoption of telehealth services, launch of new products by key players for pediatric patients, and improvements in healthcare infrastructure. In August 2021, the U.S. Department of Health and Human Services, awarded US $ 10.7 million from the American Rescue Plan to integrate telehealth services into pediatric care. This funding is meant to expand behavioral healthcare access for children.
Global Pediatric Healthcare Market:
By Offering
Anthelminthics
Antibacterials
Antifungal Medicines
Antiviral Medicines
Antiprotozoal Medicines
Others
Blood Pressure
Pulse Oximetry
Temperature Monitoring
Others
Speech Therapy
Physical Therapy
Others
By Application
Neonates (Below 28 days)
Infants (29 days to less than 2 years)
Children (2 years to less than 12 years)
Adolescents (12 years to less than 21 years)
By Distribution Channels
Online
Offline
Pharmacy & Drug Stores
Specialty Stores
Hospitals & Clinics
Others
By Region
North America
U.S.
Canada
Mexico
Rest of North America
Europe
Denmark
Finland
Iceland
Sweden
Norway
Belgium
The Netherlands
Luxembourg
Asia Pacific
Indonesia
Thailand
Malaysia
Singapore
Rest of Southeast Asia
Middle East & Africa
Saudi Arabia
UAE
Egypt
Kuwait
South Africa
Rest of Middle East & Africa
Latin America
Brazil
Argentina
Rest of Latin America
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A Controversial Autism Treatment Is About to Become a Very Big Business
When desperate parents are looking for medical treatment for their kids, especially their autistic kids, they often do two things: They look up information about a program at Duke University, and then, in short order, they go to GoFundMe. The fundraising site is full of pleas that often mirror each other, in essence saying: My child has one hope, and that hope is in stem cell and cord blood treatments.
This hope, though, is attached to treatments that are hotly disputed at best, unproven at worst, and often very expensive in either case. At Duke University’s Marcus Center for Cellular Cures, parents can enroll their children into a number of clinical trials that aim to study the effects of cells derived from umbilical cord blood on treating the effects of autism and brain injuries; adults can also participate in a trial testing whether cord blood can help them recover from ischemic strokes. And when parents can’t get their children into any of these clinical trials, particularly for autism, they often opt for what’s called the Expanded Access Program (EAP), in which they pay between $10,000 and $15,000 to get their kids a single infusion.
All of the trials use products derived from human umbilical cord blood, which is a source of stem cells as well as other types of cells. The autism trials are using a type of immune cells called monocytes, according to Dr. Joanne Kurtzberg, a well-respected Duke professor who’s conducting clinical trials into whether cord blood can help with autism, and who has been researching stem cells since the early ‘90s. (On ClinicalTrials.gov, however, these trials are listed as using mesenchymal stromal cells, which are a completely different type of cord blood cell.)
Now, a for-profit company called Cryo-Cell International with ties to Duke researchers has indicated that it plans to open clinics promoting these treatments, under a licensing agreement with the renowned North Carolina university. (Cryo-Cell acknowledged receiving a list of questions from Motherboard, but did not respond to any follow-up emails or respond to those questions before publication.) In their investor presentation, Cryo-Cell said they plan to become “an autonomous, vertically integrated cellular therapy company that will treat patients.”
Do you work for Duke University or Cryo-Cell? We would love to hear from you. Contact the reporter at [email protected], or on Signal at 267-713-9832.
Duke and Cryo-Cell’s rush to monetize a procedure before it’s shown to have solid benefits has created concern, though, across the community of scientists, clinicians, and medical ethicists who study autism treatments.
The hope is that these cord blood infusions can improve some autism symptoms, like socialization and language, or decrease the inflammation that some parents and clinicians think might exacerbate autism symptoms. Early study results, however, haven’t been very promising. A large randomized clinical trial, the results of which were released in May 2020, showed that a single infusion of cord blood was not, in the words of the researchers, “associated with improved socialization skills or reduced autism symptoms.”
This is why Duke’s latest move comes as such a surprise: The university and Cryo-Cell have told investors that they’re planning to open a series of “infusion centers.” At these clinics, Cryo-Cell will use Duke’s technology and methods to offer cord blood treatments for $15,000 per infusion.
In an exuberant presentation for investors, Cryo-Cell said it estimates an annual revenue of $24 million per clinic; it hasn’t disclosed how many clinics it plans to open. At least one will reportedly open in Durham, North Carolina.
A student walks past Duke Chapel on the campus of Duke University in Durham, North Carolina, Monday, April 30, 2007. (Photo by Jim R. Bounds/Bloomberg via Getty Images)
The move follows a June 2020 announcement that Cryo-Cell had entered into an exclusive patent-option agreement with Duke, allowing it to manufacture and sell products based on patents from Dr. Joanne Kurtzberg.
Thus far, though, Duke’s trials have not shown any promising results for cord blood products as autism treatments, granting that the research is still far from over. The university told Motherboard, “Duke’s institutional position is that additional research is required and to encourage further study to provide definitive results.” (Many autistic self-advocates object to the idea that autism needs a “cure,” and elsewhere, autism research is beginning to shift away from that language and more toward early diagnosis for children and helping autistic adults lead fulfilling and fully supported lives.)
Kurtzberg's goal, she told Motherboard in email responses provided by Duke, "is to develop and evaluate treatments that will help improve social skills and the ability to communicate with others in children with autism.” For both cerebral palsy and autism, she added, “improvements are measured using well-established tests. Among some children with cerebral palsy, improvements have been measured in gross motor function. With autism, there have been measurable improvements in communications and executive function among some study participants.”
Alycia Halladay is the chief science officer at the Autism Science Foundation, which seeks to guide families into safe, evidence-based treatments for autism. “While stem cell therapies as medical intervention for the ASD are currently being rigorously studied at Duke, it is still too early to say they actually help those on the spectrum,” she told Motherboard. “Making the move at this time to sell this therapy to families across the world is irresponsible and dangerous. It shocks and surprises me that Duke University, an institution with a stellar academic reputation, would enter into an agreement to sell intellectual property for stem cells in autism, especially since Duke has enormous financial incentive to make this profitable for Cryo-Cell.”
“I was horrified when I first heard about the Duke program,” said Anne Borden King. She’s a Toronto-based science writer and the current chair of the Campaign Against Phony Autism Cures. She also hosts the podcast “Noncompliant,” about neurodiversity, where she’s frequently spoken critically about the Duke program.
Borden King has come to believe that Duke is leveraging its reputation to run a program that’s far from ethical. “When you see a university name on a project, you think everything must be on the up-and-up,” she said. “But that’s actually not a safe assumption. Money talks.”
The idea of using therapies derived from umbilical cord blood to treat serious disorders isn’t new, and neither is the controversy around it. There are small stem cell clinics across the world, from Mexico to Panama to the Caribbean, making a host of shaky claims about the benefits that stem cells from cord blood can provide, both autologous ones (stem cells that come from the patient themselves, taken from cord blood banked at birth) and allogeneic (stem cells that come from someone other than the patient). In the past decade, small stem cell clinics have also begun to dot the United States, mostly in strip malls and similarly downmarket locales, offering treatment for things like back pain.
Stem cell clinics started to bubble into the public awareness around 2010. At that point, said Paul Knopefler, “almost all of it was outside the United States. I had people asking me, ‘Should I go to the Caribbean?’”
Knoepfler is a professor at UC Davis in the Department of Cell Biology and Human Anatomy. For the last 11 years he’s also been one of the more widely-read experts on stem cell and related therapies, with a blog called The Niche. He’s watched as these treatments went from speculative to potential cash cows; one of the earliest clinics to get a flood of attention was Celltex, a Texas firm where former Gov. Rick Perry had experimental back surgery. (NBC reported in 2011 that Perry pushed a bill that would have benefited Celltex, and he joined its board of directors in 2016, after he was no longer governor but before he joined the Trump administration as energy secretary. Perry resigned from that position in 2017.)
In the early days, Knoepfler said, “it was a mixed bag in terms of the diseases that were on people’s minds: arthritis, orthopedic issues, ranging to things more concerning to me, like parents reaching out about kids with autism or cerebral palsy.”
In the mid 2000s, agreed Leigh Turner, “I was watching this entire marketplace come into existence before my eyes.” Turner is a bioethicist and a professor in the Department of Health, Society and Behavior at UC Irvine’s public health program, and he and Knoepfler released a study in 2016 showing a huge profusion of stem cell clinics across the United States, often marketing themselves as cures for orthopedic and sports medicine problems. What they found, Turner said, was “a growing number of companies in the U.S. that were selling purported stem cell treatments not licensed by the FDA, [and which had] no meaningful evidence of safety and efficacy.” He wrote a letter to the FDA about one such clinic, urging it to investigate, before realizing that looking at the field as a whole would be a better use of his time.
Umbilical cord blood and cord, collected from hospitals, are prepared for storage at the headquarters of the Polish umbilical cord blood bank PBKM/FamiCord on November 26, 2019 in Warsaw. – Poland has emerged as Europe's leader in stem cell storage, a billion-dollar global industry that is a key part of a new therapy that can treat leukaemia but also raises excessive hope in other patients. (Photo by Wojtek RADWANSKI / AFP) (Photo by WOJTEK RADWANSKI/AFP via Getty Images)
Though stem cell clinics have been around for years, the sheen of academic and scientific legitimacy bestowed by Duke onto experimental stem cell and cord blood treatments is very new indeed. And the combination of legitimate institutional backing, money, and the hopes of desperate parents is creating a combination that critics say is combustible and potentially very risky.
At Duke, Turner said, there are respected researchers like Kurtzberg, who have, as he put it, “a long period of actual research in stem cell transplantation and meaningful research in publications, credible clinical trials. These are actual individuals who are part of the broader scientific community. It’s not the veneer of science. I imagine there are cell manufacturing and cell processing techniques that are more robust than you’d get at a strip-mall stem cell clinic.”
But there are also some similarities between what Duke is doing and the work at smaller clinics, he added. “One of them is that, at the end of the day, there are many individuals paying out of pocket. It’s not just a clinical trial. Not covered by a public or private health insurer.”
Kurtzberg is also now the medical director at Cryo-Cell, a position she took on in 2018. (A Duke spokesperson confirmed that she’s still in that role. In response to a question about how the university manages potential conflicts of interest between Kurtzberg’s two roles, they told Motherboard: “All Duke faculty must observe conflict of interest guidelines that are closely monitored by the university. Dr. Kurtzberg has reported activities with companies, institutions, or organizations outside Duke University. Any potential conflicts of interest are reviewed and, when appropriate, managed by the individual and the university.”)
Kurtzberg, in email responses provided by Duke, said that her role at Cryo-Cell was the result of the company acquiring a cord blood bank called Cord:Use, which contracted with a blood bank she founded at Duke. “When Cryo-Cell bought Cord:Use, those functions and financial arrangements continued without change.” Her salary for that job, she said, “was paid directly to the Family Support Program for the Pediatric Transplant and Cellular Therapies” at Duke.
As the cord blood market has grown, autistic children—and their often desperate, always well-meaning parents—have since begun to comprise a core market for those therapies, even as the benefits of the treatments remain largely speculative. And as Business Insider’s Tom Porter reported in January, experts in the field say that the fly-by-night clinics in other countries are getting an unintended legitimacy boost from Duke. In GoFundMe appeals, parents talk about going to overseas clinics after being unable to get into Duke, or because they felt they saw promising results from a Duke infusion and wanted another. “We have researched hospitals outside of the United States and there is a reputable medical group performing the Stem Cell Therapy in Panama City, Panama,” reads one typical plea, from a desperate mother, asking for $20,000 to get her child there.
Autistic kids and their parents are already extremely vulnerable from the start, Borden King says, due to the sheer amount of misinformation and pseudoscience that’s directed their way. She began running the Campaign Against Phony Autism Cures three years ago, after her son received an autism diagnosis. “I started meeting all these parents in meetup groups who were doing phony cures and it really shocked me, just how much of it is out there, how many different scams,” she said. “How dangerous some of them are for kids. Things like feeding kids bleach, using chelation to remove so-called ‘vaccine injury,’ and so many other things.”
She began looking at the Duke program after seeing the results of the study released in May 2020, which showed that a single cord blood infusion wasn’t effective in reducing autism symptoms. (The study authors, Dr. Kurtzberg and her colleague Dr. Geraldine Dawson, did say, however, that a subgroup of children in the study without an intellectual disability showed some improvements in “language communication, ability to sustain attention measured via eye tracking, and increased alpha and beta EEG power, a measure of brain function,” as a press release from Duke put it.)
The results were unambiguous overall, in the view of experts in the field. “This is a uniquely solid study in this area so in my view there’s not much room for hedging bets like ‘Well, maybe trying things a little different will work’ anymore,” Paul Knoepfler wrote on The Niche. “The key data in the paper are in Table II (screenshot below) showing across the board that there is no benefit of cord blood for these patients.”
“The first thing that jumped out at me when I read Duke’s study was they reported kids having health issues during infusion, like severe allergic reactions—and also being agitated and upset by the procedure,” Borden King said. (Duke’s researchers said some children experienced “agitation during IV placement and infusion” and one child experienced an allergic reaction, which was immediately treated, but they characterized most of the adverse events seen during the study as “nonserious,” and that overall the infusions were “safe and well tolerated.”)
Duke told Motherboard that “‘Cures’ is an aspirational term, not a statement about the current standard of care.”
The second thing, Borden King added, was “Duke’s own conclusion that they didn’t find any benefit from the infusions. The third thing was that they were continuing with new studies of the same thing and running a pay-to-play [in the form of the EAP program]. I thought, why? Their own studies say no evidence of benefit and clear evidence of harm. Why are they continuing?” (Duke told Motherboard, “Further research is warranted to understand the basis for favorable responses in some study participants,” referring apparently to the subgroup of children without intellectual disabilities.)
There’s one main reason why Duke has been able to run so many clinical trials relating to stem cells: Bernie Marcus, the Home Depot founder. Marcus suffered from bronchiectasis, a condition where the lungs become damaged and clogged with mucus, and sought treatment from the Stem Cell Institute (STI) in Panama, according to a blog post on its website. STI is controversial, to put it lightly. The physician and science writer Dr. David Gorski, who writes frequently about pseudoscience, especially in autism treatments, has baldly referred to it as a “quack clinic,” noting that their website “advertises stem cells to treat autism, cerebral palsy, heart failure, multiple sclerosis, osteoarthritis, rheumatoid arthritis, spinal cord injury, and autoimmune diseases, complete with very little actual science but a whole lot of testimonials.”
Home Depot CEO Bernie Marcus poses for a portrait in a Home Depot store October 15, 1998. (Photo by Erik Lesser/Liaison)
Marcus felt that the treatment he received in Panama helped his condition; soon, per the STI blog post, he was bringing his wife down to Panama for treatment to help with her knee pain. His foundation, the Marcus Foundation, soon began donating millions of dollars to both STI and Duke for stem cell research. (The Marcus Foundation could not be reached for comment: the non-profit does not maintain any kind of public-facing website or social media presence, and a phone number for them does not allow callers to leave messages. Several messages to the organzation’s program director, Elisa Levy, were returned as undeliverable.)
Bernie Marcus’ efforts in this area led, in 2018, to the founding of the institution at Duke that bears his name: the sunnily named Marcus Center for Cellular Cures.
“I think [that name] is hugely problematic,” says Jeremy Snyder, a professor in the Faculty of Health Sciences at Simon Fraser University whose research focuses on public health ethics and medical tourism, among other topics. (He and Leigh Turner have released research about misleading stem cells claims in GoFundMe appeals and the ways platforms like GoFundMe can spread health misinformation across the web. “In general crowdfunding platforms, they appear to be do very little in terms of any way vetting crowdfunding campaigns, Turner told Motherboard. “It can be a dodgy cancer clinic in Germany or a stem cell clinic in the U.S. and GoFundMe takes a hands-off approach unless there’s a groundswell of media coverage.”)
“That’s a longstanding complaint,” Snyder says, of the Marcus Center’s incredibly optimistic name. “You’ll see this in the cancer realm quite a bit. Marketing divisions of large hospitals put out commercials and different marketing materials, and you get a lot of that misleading language, playing on these tropes of hope, fighting, cures.” The point of the research, he explained, isn’t necessarily to “cure” the participants. “It’s to find out if this thing even works. If you’re getting ahead of yourself and calling it a cure, that’s deeply unethical.” (Duke told Motherboard that “‘Cures’ is an aspirational term, not a statement about the current standard of care.”)
In email responses provided by Duke, Kurtzberg told Motherboard that monocytes “can modulate inflammation, especially in the brain. In cerebral palsy, these cells promote repair of myelin—particularly in the motor tracks, which is often damaged during injuries. We have published several papers regarding this, noting the unique properties of monocytes in cord blood.”
Autism, Kurtzberg added, “is more complicated because there are multiple etiologies causing this condition. In some instances, there is inflammation of the brain, and cord blood tissue appears to calm down that inflammation in animals and lab models. We are exploring whether cells in cord blood or in cord tissue, we’re not sure which, has the ability in certain patients to calm down that inflammation and improve symptoms.”
This theory, though, is not new. As journalist Brendan Bournell reported in an extensive investigation for Spectrum News in 2019, Kurtzberg and Geraldine Dawson led a Duke team that published results in 2017 suggesting that in a trial of 22 children, all between 2 and 5 years of age, 13 had shown improvement after a single infusion. But, as Bournell noted, “Without a control group, it is impossible to say whether the children would have improved anyway.” More importantly, he wrote, “A follow-up report found that those who improved showed increased connectivity in brain regions affected by autism, including the limbic system, but the researchers published no evidence to support their inflammation theory.”
As the years have passed, Turner, Knoepfler, and Snyder have all begun asking the same basic question about the Duke program: Why is an intervention that hasn’t shown much in the way of results not only still operational, but also charging participants a lot of money to get access to it?
“We can look at their own research,” Turner said. “They haven’t done a convincing job of demonstrating efficacy. So should people have to pay what can end up being substantial amounts of money?”
Knoepfler has questions, he said, about whether the FDA is “carefully monitoring” the Expanded Access Program at Duke, which it does have to approve, at least initially. “Are they still aware Duke and Cryo-Cell want to expand this greatly?” he asked. “Is the FDA aware of the fact that hundreds of kids have gotten infused and the plans could be for thousands more? That’s where I don't have a good sense. A lot of these things are hard to tease apart. There’s different confidentiality issues.”
One especially tricky thing, he added “is that Duke must have gotten what’s called an IND, or investigational new drug applications, for cord blood or stem cells related to cord blood. That’s the basis for running a clinical trial. And anything related to an IND, the FDA views as confidential.” Indeed, in investor documents, Cryo-Cell says plainly that it plans to administer stem cell infusions under the permissions granted by Duke and Kurtzberg’s IND approval. It has gotten, Cryo-Cell’s documents add, $5 million in startup funding from the Marcus Foundation.
The FDA did not answer specific and detailed questions about Cryo-Cell’s planned infusion centers, telling Motherboard, “As a general matter, FDA cannot comment on particular applications or investigational products.” But in order to charge patients for an investigational drug under an IND application, the agency added, “the sponsor must obtain prior written authorization from FDA in accordance with FDA regulations. When charging for individual patient expanded access [sic] to an investigational drug, a sponsor may recover only its direct costs associated with making the drug available to the patient. For individual patient expanded access, the sponsor may not charge for indirect costs, including administrative costs associated with providing an investigational drug.”
“Anything related to an [investigational new drug application], the FDA views as confidential.”
The FDA also told us that stem cell therapies and other similar treatments carry some innate risk, and essentially warned that the buyer should beware:
Stem cell therapies offer the potential to improve human health, but they also create potential inherent risks for patients because of the way they may be manipulated or administered. Unproven/unapproved stem cell therapies can be particularly unsafe and have led to serious infections, blindness, and death. There are companies that are making unsubstantiated claims about the potential benefits of unproven cell therapies and their use in regenerative medicine, which is a disservice to those innovators who are working to develop safe and effective stem cell products, fully in keeping with our statues and regulations. Actions like this cast doubt across the entire field of regenerative medicine. We are concerned that people may use these unapproved products with a false sense of security about their safety and efficacy. Consumers should be cautious of any clinics, including regenerative medicine clinics, or health care providers, including physicians, chiropractors, or nurses, that advertise or offer any of these products.
The agency also said it has sent warning letters and “pursued enforcement actions for serious violations of the law” related to stem cell clinics. To date, a spokesperson wrote, it has sent “400 letters to manufacturers, clinics and health care providers, noting that it has come to our attention that they may be offering unapproved regenerative medicine products and that their activities may be subject to FDA regulation.”
In a recent blog post on The Niche, Knoepfler called on the FDA to freeze Duke’s EAP and closely examine its deal with Cryo-Cell. “The big-picture reason that I believe the agency should freeze this EAP is that it is not in the best interest of the children and their families,” he wrote. “I believe that Duke and Cryo-Cell may be too focused on ultimately profiting off of the EAP in the long run rather than just helping children.”
The science, he added, is simply not there. “Keep in mind,” he wrote, “there is no good evidence that cord blood can help kids with autism or CP. EAPs of this kind are supposed to have at least some quality data that is encouraging. I don’t see such data in this case.”
There’s also evidence that Cryo-Cell plans to extend these unproven treatments to COVID-19, which would both expand its market share and crowd an already cluttered marketplace of questionable treatments for the disease.
With funding from the Marcus Foundation, Duke is already running Phase 1 and 2 trials to see if mesenchymal stromal cells, which are also taken from cord blood, could help treat Acute Respiratory Distress Syndrome (ARDS) caused by COVID-19. Those results are not expected until 2022, but as has become a pattern with Duke and Cryo-Cell’s partnership, they’re already selling investors on the idea: Cryo-Cell’s pitch deck to investors says there are “indications under current clinical study” that mesenchymal cells from cord tissue could be used against both autism and COVID-19. (The FDA told Motherboard the agency has not approved “any regenerative medicine products, including stem cell therapies, for the treatment of COVID-19, multiple sclerosis, or autism. The only stem cell–based products that are FDA-approved for use in the U.S. consist of blood-forming stem cells (hematopoietic progenitor cells) derived from cord blood.”)
Halladay, of the Autism Science Foundation, told Motherboard she has simple advice for families looking at these treatments for autistic kids. “Families should not consider this an established, evidence-based treatment,” she wrote in an email. “Families hearing about this plan by Cryo-Cell should be suspicious and turn to their doctor or clinical team for other potential treatments and treatment combinations. This may include not just for core autism symptoms but for debilitating mental health comorbidities as well.”
In the end, the issues here extend beyond just Duke, and even the world of stem cell research, Borden King argues, noting they touch on the very nature of scientific credibility itself.
“When people think of pseudoscience, they tend to think of things like a cheesy salesman selling fake pills online,” she said. “But in my work, I see quite a few examples of autism scammers hiding behind university credentials, building hype through a university. This all has a broader impact on the credibility of our universities, which are supposed to be grounded in science. Especially at this time, when we’re fighting a pandemic and we need clear boundaries around science versus pseudoscience, the impact of projects like this just really ripples out.”
A full statement from Duke University is below:
Researchers at Duke University have studied the use of cord blood cells for pediatric blood cancers and have explored potential therapeutic applications of these cells for neurological disorders in children arising from inborn errors of metabolism, traumatic brain injury, cerebral palsy, autism and neuroinflammatory conditions.
Duke researchers are active in conducting randomized controlled clinical trials evaluating cord blood cell therapies for these applications. Data from the studies are submitted for publication in peer reviewed journals and are rigorously assessed by the scientific community and the FDA. Much remains to be learned about how these cells affect the brain and about clinical outcomes, and Duke investigators are committed to ongoing research to close these gaps in knowledge.
For some children who do not qualify for clinical studies, but who have few other options for treatment of their conditions, the FDA has authorized Duke to offer cord blood cells through an expanded access protocol (EAP) monitored by the FDA.
In recent months, Duke has entered into a licensing agreement with Cryo-Cell International to provide regulatory information and other data that would help advance the company’s effort to develop a cell therapy program eligible for approval from the FDA. This licensing agreement does not grant Cryo-Cell the use of Duke’s EAP for the treatment of patients at Cryo-Cell, but will allow Cryo-Cell to develop its own cell therapy program.
Duke is committed to ensuring that scientific evidence guides the further study and use of these investigational therapies. As new findings provide additional insights, Duke will continue to evaluate how best to move forward, both with research and with FDA-approved clinical applications.
A Controversial Autism Treatment Is About to Become a Very Big Business syndicated from https://triviaqaweb.wordpress.com/feed/
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Traditional Chinese Medicine Market is bound to reach US$ 43 Billion at a CAGR of 5.1% between 2020 to 2030
The Traditional Chinese Medicine Market is bound to reach US$ 43 Billion at a CAGR of 5.1% between 2020 to 2030. The modern-day situation says that the healthcare sector is witnessing an optimization and reposition of the business models to obtain enhanced patient outcomes. With real-time analytics known to improve patient care and the fact that consumers are shifting towards the preventive model of care, the healthcare vertical is likely to witness greater strides in the forecast period.
Traditional Chinese medicine is one of the oldest systems of health and wellness that has been used in China for thousands of years. Other medicines mainly focus on treating a disease. But traditional Chinese medicines aim to increase immune power and look at the entire well-being. The most common type of traditional Chinese medicines includes herbal products, acupuncture, and Tai Chi, among others.
According to a latest report published by PMR, the global traditional Chinese medicine market is expected to witness a CAGR of more than 5% over the forecast period (2020–2030).
Strategizing The Moves For The Next Decade? See Through Sample Of Traditional Chinese Medicine Market Report! https://www.persistencemarketresearch.co/samples/16219
Companies covered in Traditional Chinese Medicine Market Report
Tongrentang
Zhongxin Pharmaceuticals
Tianjin Tasly Group
Yuannan Baiyao
Solstice Medicine Company, Inc.
Shanghai Sundise Traditional Chinese Medicine Co., Ltd
China Chinese Medicine Holding Co., Ltd.
Hunan goldliloo pharmaceutical Co., Ltd
Wanbang Pharma Group Corp.
Chengdu Qiankun Veterinary Pharmaceuticals Co., Ltd.
Pfizer Inc.
Eli Lilly and Company
Novartis AG
GlaxoSmithKline PLC
Mallinckrodt Pharmaceuticals
Hisamitsu Pharmaceutical Co., Inc.
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Key Takeaways from Traditional Chinese Medicine Market Study
Non-traditional Chinese medicines is the leading segment by product in the global traditional Chinese medicine market. The Autism Spectrum disorder (ASD) segment has been gaining more traction in recent years, and is expected to expand at a rate of 6.7% during the forecast period.
North America is the leading region in the traditional Chinese medicine market, followed by Europe.
East and South Asia, including China, South Korea, Japan, India, and ASEAN countries, is the fastest-growing region in the traditional Chinese medicine market, due improving medical infrastructure.
Tong Ren Tang, Pfizer, and Novartis AG are amongst the leading players in the global traditional Chinese medicine market. These companies invest most of their revenue in R&D, and focus on strengthening their distribution channels to maintain a leading position in the traditional Chinese medicine market space.
100+ health systems are partnering with retail chains, providing physician oversights and increased patient traffic to retail clinics, and extending health system networks to new patient populations.
The COVID-19 pandemic is a cause for concern, which has deprioritized non-essential medical treatments. This will hurt the growth of the global traditional Chinese medicine market in the short term.
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“Increasing incidence of ADHD to boost growth of global traditional Chinese medicine market,” says a PMR analyst.
Rising prevalence of ADHD is a major factor contributing to revenue growth of the traditional Chinese medicine market across the globe. The exact cause of ADHD is still unclear, although genetic influence is observed in most cases.
As per data released by the Centers for Disease Control and Prevention (CDC), approximately 6.1 million (9.4%) – 388,000 children aged 2–5 years, 4 million children aged 6–11 years, and 3 million children aged 12–17 years – were diagnosed with ADHD in the U.S. In Spain, pooled prevalence of ADHD in a population of 361,580 representing children and adolescents was estimated at 6.8% from the last decade.
Prevalence of ADHD is rising at an alarming rate, which is expected to fuel revenue growth of ADHD therapeutics such traditional Chinese medicines, as there is no specific treatment for this disorder.
Product Innovation – Key Strategy of Traditional Chinese Medicine Market Players
Major players in the global traditional Chinese medicine market are introducing innovative products to retain their market share. A patented technology called osmotic controlled release oral delivery system (OROS) is used in Concerta, manufactured by Johnson & Johnson. It releases an initial dose of methylphenidate within the first two hours of ingestion, and when the pill passes through the stomach and gastrointestinal track, water is absorbed, resulting in internal pressure, which releases small amounts of medication as the pill passes through gut. This technology was implemented to maintain consistency of improvement in cognitive performance throughout the day.
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Rosemary Extracts Market: Global Industry Analysis, Trends, Market Size, and Forecasts up to 2025
The report on the global rosemary extracts market provides qualitative and quantitative analysis for the period from 2017 to 2025. The report predicts the global rosemary extracts market to grow with a CAGR of 4.5% over the forecast period from 2019-2025. The study on rosemary extracts market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and RoW for the period of 2017 to 2025. The report on rosemary extracts market is a comprehensive study and presentation of drivers, restraints, opportunities, demand factors, market size, forecasts, and trends in the global rosemary extracts market over the period of 2017 to 2025. Moreover, the report is a collective presentation of primary and secondary research findings.
Request to Fill The Form To get Sample Copy of This Report: https://www.sdki.jp/sample-request-103745 Porter's five forces model in the report provides insights into the competitive rivalry, supplier and buyer positions in the market and opportunities for the new entrants in the global rosemary extracts market over the period of 2017 to 2025. Further, IGR- Growth Matrix gave in the report brings an insight into the investment areas that existing or new market players can consider. Report Findings 1) Drivers • The growing popularity regarding natural preservative over artificial additive among the food and beverage industry • Nowadays, manufacturers are looking for natural additive to extend the shelf life of their products, which in turns, the growth of natural preservative is increased 2) Restraints • Availability of cheaper artificial additive 3) Opportunities • Research and development and innovation to use of rosemary extracts in various end-user industries Research Methodology A) Primary Research Our primary research involves extensive interviews and analysis of the opinions provided by the primary respondents. The primary research starts with identifying and approaching the primary respondents, the primary respondents are approached include 1. Key Opinion Leaders associated with Infinium Global Research 2. Internal and External subject matter experts 3. Professionals and participants from the industry Our primary research respondents typically include 1. Executives working with leading companies in the market under review 2. Product/brand/marketing managers 3. CXO level executives 4. Regional/zonal/ country managers 5. Vice President level executives. B) Secondary Research Secondary research involves extensive exploring through the secondary sources of information available in both the public domain and paid sources. At Infinium Global Research, each research study is based on over 500 hours of secondary research accompanied by primary research. The information obtained through the secondary sources is validated through the crosscheck on various data sources. The secondary sources of the data typically include 1. Company reports and publications 2. Government/institutional publications 3. Trade and associations journals 4. Databases such as WTO, OECD, World Bank, and among others. 5. Websites and publications by research agencies Segment Covered The global rosemary extracts market is segmented on the basis of form, nature, and application. The Global Rosemary Extracts Market by Form • Powder • Liquid The Global Rosemary Extracts Market by Nature • Conventional • Organic The Global Rosemary Extracts Market by Application • Food and Beverages • Pharmaceuticals • Personal Care Industry • Others Company Profiles The companies covered in the report include • Naturalin Bio-Resources Co., Ltd • Changsha E.K HERB Co., Ltd. • Kalsec Inc. • FLAVEX Naturextrakte • Frutarom Industries Ltd. • Hainan Super Biotech Co., Ltd. • Kemin Industries • Geneham Pharmaceutical • Danisco A/S • Other Companies What does this report deliver? 1. Comprehensive analysis of the global as well as regional markets of the rosemary extracts market. 2. Complete coverage of all the segments in the rosemary extracts market to analyze the trends, developments in the global market and forecast of market size up to 2025. 3. Comprehensive analysis of the companies operating in the global rosemary extracts market. The company profile includes analysis of product portfolio, revenue, SWOT analysis and latest developments of the company. 4. IGR- Growth Matrix presents an analysis of the product segments and geographies that market players should focus to invest, consolidate, expand and/or diversify.
The dynamic nature of business environment in the current global economy is raising the need amongst business professionals to update themselves with current situations in the market. To cater such needs, Shibuya Data Count provides market research reports to various business professionals across different industry verticals, such as healthcare & pharmaceutical, IT & telecom, chemicals and advanced materials, consumer goods & food, energy & power, manufacturing & construction, industrial automation & equipment and agriculture & allied activities amongst others.
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Autism Spectrum Disorder Therapeutics Market To Surpass US$ 5,225.5 Million By 2027
Global Autism Spectrum Disorder Therapeutics Market, by Drug Type (Aripiprazole, Risperidone, Melatonin, CM-AT, Bumetanide, and Balovaptan), by Age Group (Child and Adult), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) was valued at US$ 2,285.5 million in 2019 and is projected to exhibit a CAGR of 10.9% over the forecast period (2019 - 2027).
Increasing investigational research and funding support for pharmacogenomics-based drug discovery is a major factor driving growth of the autism spectrum disorder therapeutics market. Various organizations are focused on receiving approvals to investigate novel drugs for the treatment of ASD. For instance, in January 2018, Roche announced that the U.S. Food and Drug Administration (FDA) granted breakthrough therapy designation for its investigational oral medicine balovaptan, a vasopressin 1a (V1a) receptor antagonist for individuals with ASD. Balovaptan demonstrated potential to improve social interaction and communication in people with ASD. Similarly, in May 2018, the U.S. FDA granted fast track designation for Yamo Pharmaceuticals’ investigational drug L1-79, a tyrosine hydroxylase inhibitor intended to diminish the socialization and communication symptoms in individuals with ASD. L1-79 demonstrated potential to address an unmet medical need for treatment of core symptoms of ASD.
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Increasing funding for the research of ASD drugs is expected to contribute in the ASD therapeutics market size. For instance, in June 2018, Innovative Medicines Initiative funded US$ 132 million to a research grant titled Autism Innovative Medicine Studies-2-Trials (AIMS-2-Trials), which is academically co-led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and F. Hoffmann-La Roche, Basel. Manufacturers in the autism spectrum disorder therapeutics market are focused on adopting collaboration and partnership strategies to enhance their market share. For instance, in 2017 Servier Laboratories Ltd. and Neurochlore announced signing of an exclusive licensing agreement to develop and market bumetanide for pediatric autism in Europe. Under this agreement, Servier Laboratories Ltd. will develop and market the product in Europe and Neurochlore will retain these rights for the U.S. market.
Browse 146 Market Data Tables and 30 Figures spread through 308 Pages and in-depth TOC on "Global Autism Spectrum Disorder Therapeutics Market, by Drug Type (Aripiprazole, Risperidone, Melatonin, CM-AT, Bumetanide, and Balovaptan), by Age Group (Child and Adult), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Global Forecast to 2027"
Furthermore, government organizations are focused on conducting workshops for parents and caregivers of children with developmental disorders, which is expected to aid in the ASD therapeutic market growth. For instance, a workshop jointly led by Pan American Health Organization, World Health Organization, and Autism Speaks is organized annually in the month of August in Buenos Aires, Argentina, to teach skills and raise awareness about autism and its preventive measures.
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Key Takeaways of the Autism Spectrum Disorder Therapeutics Market:
The global autism spectrum disorder therapeutics market is expected to witness a CAGR of 10.9% during the forecast period (2019–2027), owing to increasing drug approvals, investigational studies, and funding
Among drug type, the Aripiprazole segment is expected to hold major revenue share in 2019-2027, owing to increasing production of generics of Aripiprazole. For instance, in April 2015, the U.S. Food and Drug Administration (FDA) approved the pharmaceutical companies Alembic, Hetero Labs, Teva, and Torrent for manufacturing the generic version of Bristol-Myers Squibb’s Abilify oral tablets.
Major players operating in the global autism spectrum disorder therapeutics market include, F. Hoffmann-La Roche AG, Neurim Pharmaceuticals, Inc., Yamo Pharmaceuticals LLC, Servier Laboratories Ltd., Otsuka Holdings Co. Ltd., Curemark LLC, Oryzon Genomics S.A., GW Pharmaceuticals Plc., Teva Pharmaceutical Industries Ltd., Zynerba Pharmaceuticals Inc., Stalicla SA., Novartis AG, Pfizer, Inc., and Bristol Myers Squibb.
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Neurological Biomarkers Market Projected To Have Valuation Worth USD 16.5 Billion By 2026
The global neurological biomarkers market size is expected to reach USD 16.5 billion by 2026, according to a new report by Grand View Research, Inc. It is estimated to register a CAGR of 14.5% over the forecast period, driven by an increasing prevalence of neurological diseases and emergence of novel diagnostic products.
Neurological biomarkers can be used for diagnostics, drug discovery, or personalized medicines among other applications. These products may be employed in drug development to reduce attrition rates during clinical trials. Some neurological biomarkers can further be used to predict drug failures early in the development process by determining their pharmacological effect on patients, which helps the pharmaceutical company obviate additional costs associated with further clinical trials.
There remains a significant dearth for in-depth knowledge of the pathophysiologies of several neurological disorders, thus resonating with the unmet need for more research and increased funding for the same. Though technological advancements and rising consumer awareness are flag-bearers in this market growth, there remains considerable scope for advanced diagnostics - in terms of precision, specificity, and test time.
The diagnostic landscape in this market is gradually shifting towards genetic testing and counseling. Biomarker signatures are a rising trend in the diagnosis and treatment of neurological diseases. This has resulted in non-invasive testing, faster drug development, and early diagnosis of abnormalities/diseases. Furthermore, digital biomarkers provide various pharmaceutical companies with contextual and supplemental information to conclude clinical trial decisions. For instance, IXICO plc is collaborating with biopharmaceutical companies to validate clinically digital biomarkers and use them in clinical trials.
Proactive initiatives by public and private organizations to heighten consumer awareness is a key driver of the neurological biomarkers market. For instance, the National Alliance on Mental Illness (NAMI) one of the largest grassroot organizations in the U.S. is dedicated to educating, advocating, and supporting mental health patients about diagnosis and apt treatment for their conditions. Such drivers reflect a prosperous future in the global biomarkers market.
To request a sample copy or view summary of this report, click the link below: www.grandviewresearch.com/industry-analysis/neurological-biomarkers-market
Further key findings from the report suggest:
Most biomarkers evaluating neuronal damage cannot be clinically useful individually, and are generally used in panels
Most cerebrospinal fluid biomarkers used in medical practice are amyloid β and tau proteins
Nascent products allow a broader scope for characterization and selection of treatment strategies
Inconsistent regulatory trends remain a major constraint for the market
Asia Pacific is positioned to witness the fastest regional growth
Grand View Research has segmented the global neurological biomarkers market based on application, type, end-use, and region:
Application Outlook (Revenue, USD Million, 2015 - 2026)
Alzheimer’s Disease
Parkinson’s Disease
Multiple Sclerosis
Autism Spectrum Disorders
Others
Type Outlook (Revenue, USD Million, 2015 - 2026)
Genomic
Proteomic
Metabolomic
Imaging
Others
End-Use Outlook (Revenue, USD Million, 2015 - 2026)
Hospital Laboratories
Independent Clinical Diagnostic Centers
Research Organizations
Others
Regional Outlook (Revenue, USD Million; 2015 - 2026)
North America
Europe
Asia Pacific
Latin America
Middle East & Africa`
U.S.
Canada
U.K.
Germany
France
Italy
Spain
Japan
China
India
South Korea
Australia
Brazil
Mexico
Argentina
South Africa
Saudi Arabia
UAE
About Grand View Research
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.
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ADHD Therapeutics Market Share, Growth By Top Company, Application, Driver, Trends & Forecasts By 2027
ADHD Therapeutics Market Overview
Attention Deficit Hyperactivity Disorder, majorly known as ADHD is a neuro-developmental condition that mostly occurs in the childhood and continues in adulthood if not treated in time. Symptoms of ADHD include combinations of tenacious issues such as impulsive behavior, difficulty in sustaining attention, and hyperactivity, etc.
The exact cause leading to the occurrence of ADHD is not known. However, some environmental factors such as premature birth, prenatal tobacco exposure, and genetics are considered as severe risk factors for ADHD. Similarly, there is no breakthrough treatment for ADHD, but early detection & treatment can help patients to manage their conditions.
Over the past few years, the global ADHD therapeutics market has been growing rapidly, mainly due to the growing prevalence of ADHD and the advancements in the therapeutics to manage its conditions. The increasing uses of ADHD medicines indicate that the numbers of patients being diagnosed and treated have been increasing.
Considering the traction, the market is vibrating with; Market Research Future (MRFR) in its recently published study report asserts that the global ADHD therapeutics market gaining further prominence will register a spectacular growth along with a striking CAGR throughout the forecast period (2017 – 2024).
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The burgeoning healthcare sector along with the increasing number of advanced care providing facilities substantiates the market growth. However, the number of patients receiving the quality treatment, worldwide, is yet far little. In few of the developing regions, ADHD is still under-diagnosed and remains untreated often.
The well-established ADHD therapeutics market perceives several options available for diagnosis and treatments, ranging from behavioral intervention and prescription medication to digital medicines. Additionally, there are antibiotics developed with technological interventions to provide preferable outcomes.
Spreading awareness among people about the disorder and the availability of various therapeutics to treat its conditions is a key factor fostering market growth. Evidently, improving economic conditions worldwide act as a major tailwind pushing up the market growth by availing improved healthcare.
Conversely, factors such as incidents of drug resistance, unmet clinical needs, and the high cost associated with the treatments are likely to impede the market growth. However, emerging Biosimilars are expected to support market growth, availing affordable, cost-effective medical products.
ADHD Therapeutics Market - Segmentations
MRFR has segmented the report into three key dynamics for an easy grasp;
By Drug Type : Stimulants, Non-stimulants and others.
By Distribution Channel : Hospitals, Pharmacies, Clinics, and Research Laboratories among others.
By Regions : Asia Pacific, Europe, North America, and Rest-of-the-World (RoW).
ADHD Therapeutics Market - Regional Analysis
The North American region accounts for the leading market for ADHD therapeutics, Globally. The ADHD therapeutics market in this region commands the largest market share, followed by Europe & Asia Pacific market, respectively. The US ADHD therapeutics market heading with the high healthcare expenditure leads the regional market. Continuing with the same growth trends in the future, North America is expected to retain its dominance over the global ADHD therapeutics market, creating a large revenue pocket throughout the forecast period.
Heading with the significant technological advancements and the emergence of digital medicines, the ADHD therapeutics market in the European region holds the second position in terms of the size. Moreover, the presence of a flourishing medical devices market and rising healthcare expenditure in the region are estimated to facilitate the growth of the market.
The Asia Pacific ADHD therapeutics market is emerging as a lucrative market, worldwide. The factors substantiating the market growth include the huge population, large unmet needs, and the availability of low-cost drugs for ADHD treatment. Besides, the improving economic conditions in the region are acting as a key driving force pushing up the market growth by boosting the healthcare sector.
Increasing funding support from the public and private bodies are supporting the market growth in the region, increasing R&D activities. Furthermore, the rising penetration of healthcare insurance mainly in the countries such as Malaysia, Thailand, and Vietnam alongside the availability of new treatment methods that are increasingly meeting the growing demand for the treatments is expected to drive the ADHD therapeutics market in the in the Asia Pacific region.
Global ADHD Therapeutics Market - Competitive Analysis
The highly competitive, ADHD therapeutics market appears to be fragmented characterized by the presence of various large and small-scale players. Well-established players incorporate strategic initiatives such as acquisition, partnership, collaboration, expansion, and product launch to gain a competitive edge and to maintain their positions in the market.
ADHD Therapeutics Market Key Players:
Key players leading the global ADHD therapeutics market include Concordia International Corp., Highland Therapeutics Inc., Eli Lilly and Company, Janssen Global Services LLC, Novartis AG, NEOS Therapeutics Inc., Noven Pharmaceuticals Inc., Teva Pharmaceutical, Shire, and Pfizer Inc. among others.
ADHD Therapeutics Industry/Innovations/Related News:
January 04, 2019 – Researchers at Children's Hospital of Philadelphia (US) published the results of the study wherein they evaluated a digital medicine tool – EVO designed for investigational treatment for children with autism spectrum disorder (ASD) and co-occurring attention/deficit-hyperactivity disorder (ADHD). The outcomes published in the Journal of Autism and Developmental Disorders confirmed the acceptability, feasibility, and safety of EVO designed by Akili Interactive, a prescription digital medicine company. EVO delivers sensory and motor stimuli through an action video game experience.
#ADHD Therapeutics Market#ADHD Therapeutics Market Size#ADHD Therapeutics Market Share#ADHD Therapeutics Market Growth#ADHD Therapeutics Market Analysis
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By 2026 Adaptive Strollers Market To Surpass US$ 590 Million - Coherent Market Insights
Adaptive Strollers Market To exhibit a CAGR of 7.8% over the forecast period (2018 - 2026).
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Description:
Adaptive stroller is a special mobility equipment that is designed to offer smooth mobility and comfortable seating for patients with neurodegenerative disorders. It offers a lighter and more portable alternative to wheelchair. Adaptive strollers can be equipped with accessories that help with comfortable positioning and posture. For younger children, strollers are an appropriate alternative to a wheelchair and are more easily transported in cars than heavier wheelchairs. Adaptive strollers are available for nearly all sized clients and frame adjustments and seating options vary significantly among different models.
The global adaptive stroller market size was valued at US$ 313.4 million in 2017 and is expected to witness a CAGR of 7.8% over the forecast period (2018 – 2026)
Global Adaptive Strollers Market Share (%) Analysis, By Product 2017
Adaptive Strollers | Coherent Market Insights
Source: Coherent Market Insights Analysis (2018)
Increasing prevalence of neurodegenerative diseases is expected to drive the adaptive stroller market revenue
Neurodegenerative disease is an array of conditions, which primarily affects the neurons in the human brain. It is an incurable and devastating conditions that results in progressive degeneration and death of nerve cells, which causes problems with movement or mental functioning. Spinal Muscular Atrophy (SMA) and motor neuron diseases are the most common neurodegenerative diseases in children. SMA affects the motor neurons that control body movement.
According to a report published in the PLOS One journal, 2018, SMA is the leading genetic cause of infant death worldwide, with an incidence of around 1 per 10,000 newborns worldwide. Cerebral palsy is also the most common motor disability in childhood. According to the Centers for Disease Control and Prevention’s (CDC) 2014 report, an average of one in every 323 children in the U.S. suffer from cerebral palsy.
Adaptive Strollers Market Restraints
High product cost and limited features as compared to wheelchair are the major factors expected to confine the adaptive stroller market growth during the forecast period. Adaptive strollers generally use the same manufacturer’s seating options, whereas manual wheelchairs can accommodate a variety of manufacturers’ seating systems and components, depending on the customer need.
Adaptive Strollers Market - Regional Insights
On the basis of region, the global adaptive strollers market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America adaptive strollers market is expected to generate major revenue share during the forecast period. This is owing to increasing investment of government in the healthcare sector coupled with a large number of children suffering from mobility disorders. According to the CDC 2014 report, the expenditure on treatment for a child with Autism Spectrum Disorder (ASD) was US$ 17,000, annually and it increased to over US$ 21,000, annually for a child with more severe ASD.
Europe adaptive stroller market size is expected to witness significant growth, owing to higher prevalence of SMA in the region and increasing charity and funding for adaptive stroller by various government and private organizations such as The ACT Foundation, Action For Kids, and Cerebra. According to the NHS 2014 report, approximately 5,500 to 6,000 people in the UK were suffering with some form of SMA.
Global Adaptive Strollers Market Revenue 2017 (US$ Mn), By Region
Adaptive Strollers | Coherent Market Insights
Source: Coherent Market Insights Analysis (2018)
Adaptive Strollers Market - Competitive Landscape
Key players operating in the global adaptive strollers market include, Adaptive Star, Assistive Technology, Inc., Convaid Products, Inc., Deming Designs Inc., Eurovema Ab, Invacare Corporation, Meyra, Ormesa, Performance Health, Special Tomato, Sunrise Medical LLC, R82 Inc., and Thomashilfen.us.
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The Global Autism Spectrum Disorder Therapeutics (ASD) Market was leading by US$ 2,285.5 million in 2019.
Summary:The Global Autism Spectrum Disorder Therapeutics (ASD) Market is expected to grow for CAGR of 10.9% during 2019–2027.
Key Trends:
Autism Spectrum Disorder Therapeutics divided in symptoms such as core and associated.Core symptoms include impairment of social interaction and communication while associated spectrums include sleep deficits, language disability, mood swings, and self-injury.
Increasing prevalence of autism spectrum disorders and growing number of fast track designations are the major drivers of Autism Spectrum Disorder Therapeutics Market.
Furthermore, in September 2017, Curemark conducted second Phase III clinical trial: Blüm Study— to evaluate the safety and efficacy of CM-AT in children aged 3-8 with ASD.
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Regional Analysis:
Due to increasing prevalence of ASD in the pediatric population of the U.S. the global autism spectrum disorder therapeutics market is witnessing significant growth in regions i.e.North America, Latin America, Europe, Asia Pacific, Middle East, and Africa over the forecast period.
Asia Pacific is anticipated to be the second most popular region in terms of rapid growth in the autism spectrum disorder therapeutics market revenue to the rising awareness about different therapies.
Competitive Landscape
Key players operating in the global autism spectrum disorder therapeutics market include, F. Hoffmann-La Roche AG, Neurim Pharmaceuticals, Inc., Yamo Pharmaceuticals LLC, Servier Laboratories Ltd., Otsuka Holdings Co. Ltd., Curemark LLC, Oryzon Genomics S.A., GW Pharmaceuticals Plc., Teva Pharmaceutical Industries Ltd., Zynerba Pharmaceuticals Inc., Stalicla SA., Novartis AG, Pfizer, Inc., and Bristol Myers Squibb.
Market Segmentation:
By Type
Autistic Disorder
Asperger Syndrome,
Pervasive Developmental Disorder
By Treatment
Communication & Behavioral Therapies
Drug Therapies
By Distribution Channel
Hospitals
Retail Pharmacies
Online Channels
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Related Topics:
ANDROGEN REPLACEMENT THERAPY MARKET
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy, in which androgens, often testosterone, are replaced. ART is often prescribed to counter the effects of male hypogonadism. It typically involves the administration of testosterone through injections, skin creams, patches, gels, or subcutaneous pellets. Testosterone replacement therapy is a promising technology for improving symptoms of hypogonadism and to raise the testosterone level.
HEALTHCARE CONTRACT RESEARCH OUTSOURCING MARKET
Healthcare Contract Research Outsourcing is conducted by pharmaceutical and medical device sectors for development of new drugs and medical devices. Clinical trials form the key part of pharmaceutical drug and medical device development and in the current scenario clinical trials are conducted across multiple locations in various geographies. Increasing cost and time required for drug development is expected to propel growth of the global healthcare contract research outsourcing market over the forecast period.
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Revenue from the Speech Therapy Services Market research to Increase Exponentially During 2017 – 2025
Speech therapy services involves the treatment of communication and speech related disorders. This includes the different approaches which are used to treat patients based on the disorder, and includes physical exercises, speech drills, sound production practice etc. to reinforce the muscles and improve voice clarity and articulation. Speech therapy also involves the treatment of people who have problems in pronounce words correctly. Speech therapy market trends propose that demands of such therapies will increase in end users such as school, bilingual classes, corporate settings, and private practices.
Speech and communication loss is strongly associated with aging. Increase in elderly population will give the opportunity to speech therapy service providers to balance impairments as the number of persons with speech problems will increase rapidly. Baby boomers are now facing the problems of neurological disorders and increases in associated hearing impairments and this will boost market opportunity for speech therapy services providers. Speech therapy demand may be greater in the areas with large numbers of retirees. Medical advances have increased the survival rate of premature infants, and trauma and stroke victims, who then need assessment and possible treatment in speech related problems.
Increase in awareness of the importance of early diagnosis and identification in infants is going to boost the demand of speech therapy services over the forecast years. Increase in screening of newborns for speech and hearing impairment to receive suitable intervention services are opening new window for existing and emerging market players. Demand of speech therapy services is increasing in elementary and secondary school for special education students. Increasing demand for contract based and direct services to individuals in hospitals, schools, and nursing care facilities is expected drive the growth of speech therapy services in near future.
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The global Speech Therapy Services market is segmented on basis of age group, indication, and geography
Segment by Age Group
Pediatrics
Adults
Elderly
Segment by Indication
Speech Disorder
Language Disorder
Apraxia
Autism Spectrum Disorder (ASD)
Other Disorders
Articulation Disorders
Fluency Disorders
Resonance Or Voice Disorders
Receptive Disorders
Expressive Disorders
Cognitive-communication Disorders
Global speech therapy services market is segmented by age group, indication and geography. Based on the age group, global speech therapy services market is segmented as pediatric, adult and elderly population. Based on indication, the speech therapy services market is segmented as speech disorders, language disorder, apraxia, autism spectrum disorder (ASD), and other disorders. Speech disorders further includes, articulation disorders, fluency disorders, resonance or voice disorders and language disorder includes receptive disorders, expressive disorders, and cognitive-communication disorders. Rise in incidence of congenital disorders, increased awareness, early diagnosis and new services launch is expected to drive the global speech therapy services market during the forecast period. Whereas inadequate access to health care, cost and lack of availability of essential services in remote areas, insufficient number of healthcare professional for speech therapy and lack of standardized tools for diagnosis and treatment is expected to hinder the growth of global speech therapy services market.
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By Geography, the global speech therapy services market is segmented into five broad regions viz. North America, Latin America, Europe, Asia-Pacific, and the Middle East & Africa. North America is estimated to lead the global speech therapy services market due to rise in incidence of congenital disorders, increase in elderly population etc. Europe market is also projected to experience high growth in the near future. Asia Pacific market is anticipated to grow at a substantial growth rate during the forecast period, owing to factors such as rising standard of living, lifestyle changes, increase in awareness for speech disorders and focusing on healthcare expenditures.
Some of the major players in global speech therapy services market are Smart Speech
Therapy LLC
Therapy Solutions Inc.
Glenda Browne Speech Pathology
Benchmark Therapies
Talk Speech and Language Therapy Ltd
Speech Plus
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Autism Spectrum Disorder Therapeutics Market - Size, Share, Outlook,
Autism Spectrum Disorder Therapeutics Market – Insights
Autism Spectrum Disorder (ASD) is a neurodegenerative disorder, which is associated and often overlaps with other conditions such as epilepsy, frequent infections, sleep disorders, anxiety, depression, and gastrointestinal problems. ASD is only diagnosed by developmental and comprehensive tests. It can be detected at eighteen months to two years of age. Drugs such as Aripiprazole, Risperidone, and Melatonin are U.S. Food and Drug Administration (FDA) approved drugs that aid in the treatment of ASD. Bumetanide and Balovaptan are the drugs that are under clinical trial and investigation to evaluate their safety and efficacy for the treatment of ASD.
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Increasing Number of Pipeline Drugs and Early Diagnosis of ASD is expected to Drive Growth of the Autism Spectrum Disorder Therapeutics Market
Increasing number of pipeline drugs and launches of novel products by key players are expected to be the major driving factors for the global autism spectrum disorder therapeutics market growth during the forecast period. For instance, in February 2014, the company was awarded six new patents for its enzyme delivery system in Europe, Australia, and Central America, which can be utilized for multiple enzyme products including CM-AT— Curemark’s proprietary ASD drug.
Furthermore, in September 2017, Curemark conducted second Phase III clinical trial: Blüm Study— to evaluate the safety and efficacy of CM-AT in children aged 3-8 with ASD.
Autism Spectrum Disorder Therapeutics Market - Restraints
Shortage of specialist doctors to diagnose ASD accurately is one of the major factors, which is expected to hamper the ASD therapeutics market. For instance, according to Simons Foundation Autism Research Initiative’s (SFARI) research, in 2018, there are only 8,300 child psychiatrists, 1,500 child neurologists, and 1,000 developmental-behavioral pediatricians for over 1 million autistic children in the U.S. The shortage of specialist doctors to diagnose ASD hampers growth of the ASD therapeutic market.
Autism Spectrum Disorder Therapeutics Market - Regional Insights
On the basis of region, the global autism spectrum disorder therapeutics market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold a dominant position in the global autism spectrum disorder therapeutics market during the forecast period, owing to increasing prevalence of ASD in the pediatric population of the U.S. For instance, according to the Centers for Disease Control and Prevention’s (CDC) report released in April 2018, 1 in every 59 children was identified with ASD in the age range of 3 to 17 years in 2014.
Asia Pacific is expected to foresee a rapid growth in the autism spectrum disorder therapeutics market revenue. This is owing to increase in sales of Aripiprazole for the treatment of ASD. For instance, in 2017, Otsuka Pharmaceutical’s ABILIFY MAINTENA (Aripiprazole) generated US$ 62.9 million in revenue with a growth of 24.1% compared to the revenue in 2016. Moreover, ABILIFY accounted for a revenue of US$ 59.7 million in 2017.
Autism Spectrum Disorder Therapeutics Market - Competitive Landscape
Key players operating in the global autism spectrum disorder therapeutics market include, F. Hoffmann-La Roche AG, Neurim Pharmaceuticals, Inc., Yamo Pharmaceuticals LLC, Servier Laboratories Ltd., Otsuka Holdings Co. Ltd., Curemark LLC, Oryzon Genomics S.A., GW Pharmaceuticals Plc., Teva Pharmaceutical Industries Ltd., Zynerba Pharmaceuticals Inc., Stalicla SA., Novartis AG, Pfizer, Inc., and Bristol Myers Squibb.
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