#5a-reductase deficiency
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Dr. Heinz Doofenschmirtz from Phineas and Ferb is intersex, and his variation is 5alpha-Reductase Deficiency (5ARD)!
#admin post#pnf fandom come get y'all juice#intersex4intersex doofperry when#intersex#intersex headcanon#5alpha-reductase deficiency#5a-reductase deficiency#5ARD#heinz doofenshmirtz#dr doofenshmirtz#doctor doofenshmirtz#phineas and ferb#phineas & ferb#pnf#he also has light coding bcuz its been said he was raised as a girl? iirc?#has trans themes too and I was tempted to edit him with the trans flag but it's late as shit and I need a shower.#so. uh. sorry. lazy!#leaves open-endedness too if y'all enjoy that. I Guess.
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Isn't that boxer being discussed female tho?
the reporting is really murky which is why i was trying to figure out what was actually going on before saying anything, but from what i can tell (which, again, murky) it's a semenya-like situation where someone with xy has something like 5a reductase deficiency or androgen insensitivity (both of which are male-specific DSDs)
the specifics are being kept confidential but multiple tests have supported the disqualification
either way i think i'd trust the olympic-level boxer to know what kinds of force she's been up against before, and i doubt she'd tap out that early unless something was really wrong
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Look, sometimes the best thing to do for your mental health is to write a five pages genetics research paper on the variance of primary sexual characteristics due to irregularities in the placement of the SRY coding gene, functional androgen receptors, and deficiencies in the 5a-reductase enzyme responsible for converting testosterone to dihydroxytestosterone purely so people can write more engaging worldbuilding for pornography tangentially related to werewolves.
The fact that it was a week before an episode of psychosis is completely beside the point. Now, I'm off to compile my sources from the Books of Enoch and the Genesis Apocryphon found in the Dead Sea scrolls in order to explain why Noah was a twink.
No weapon formed by the hand of man can stop this, because God won't let me die. Thank you.
Coping mechanisms for the mentally disturbed: debating on writing out several academic-style mla-cited explorations of various fanfic tropes that people either 1) don't really care about or 2) are aware of because everyone only ever hears about that trope for the absolute batshit insane kink shit
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Baldness can be treated
Baldness can be treated, however, at some point; most folks are getting to experience hair loss. In the world, approximately half all men (and women, too) will start showing signs of baldness by their 40th birthday. Even though modern folklore, and even some limited scientific studies, has suggested that the mother's side of the family is basically accountable for a genetic predisposition toward baldness, the reality is balding isn't all our mothers' fault. In fact, doctors now say baldness patterns are inherited from a mixture of many genes on each side of the family. There are some environmental factors that inherit play, too.
As the blandness can be treated so, scientists are beginning to inch closer to finding a cure for the missing hair problem. But within the meantime, here are a couple of proven ways to stop baldness, and help grow back lost hair. But it also can be caused by environmental factors like poisoning, radiation, certain drugs, infections, hormone disorders, or nutrition deficiencies. Also, physical stressors like sudden weight loss or pregnancy, or other physical, or emotional shocks, can cause temporary hair loss.
Hair growth promoters (alopecia treatment)
Treatment regime of alopecia:
Baldness can be treated by using hair growth promoters that claim to be useful for alopecia treatment steadily growing as a multibillion‒dollar market. Few research areas and lots of patents claiming because of the anti‒alopecic agents and yet, pharmaceutical alopecia management still within a clinical test phase. There are many drugs available to extend the hair growth on the head. Minoxidil also reduces hair loss and maintains hair growth. Numerous other allopathic and herbal products are available in the marketplace for hair growth, and hair care.
��Herbal drug utilized in alopecia treatment in Pakistan
Use of synthetic drugs are related to many adverse drug reactions and usually not prescribed for effective and safe management of alopecia. Therefore, the natural origin drugs have emerged as an alternative to scale back the adverse drug reaction related to synthetic drugs. To cope with the alopecia problem, here we've looked into the treasure of natural origin and located a variety of natural products which are effective for alopecia treatment. Many benefits are related to natural products like fewer side effects, improved patient compliance and poly herbal treatment gives quite one mode of an action for the treatment of Alopecia. The natural product utilized in the treatment of alopecia are usually DHT blockers and 5‒α‒Reductase blockers, and provides nutritional requirement and improved scalp blood circulation Iron, copper, chromium, zinc, and magnesium are vital to take care of healthy hairs and natural products provide these mineral to manage the blood circulation that increases hair growth. Vitamin B-complex vitamin (B6, B3, B5 and folic acid), biotin (biotin source is: ingredient, whole grains, rice and milk) and vitamin. An important for hair growth because it keeps the hair root lubricated. Herbal drugs also are utilized in aromatherapy, which are taken orally and therefore, the essential oils present in herbal drugs directly reach the vessel, where they are attached to receptors. These essential oils work on a cellular level to calm the system, providing a way of well‒being. Aromatherapy stimulates blood circulation at the base of hair follicles and it's proved as effective and safest thanks to coping up with different sorts of hair loss (alopecia). However, exact pharmacological actions of those herbs and oils are yet not known. Plant extracts having multiple phyto‒constituents and may treat hair loss either by providing or by acting as DHT and 5‒α‒Reductase blockers or nutritional supplements. They even have volatile oil which may be helpful in treating alopecia by aromatherapy by improving blood circulation in the scalp.
Synthetic drugs within the treatment of alopecia:
Baldness can be treated by using various drugs, for the treatment of alopecia are originally developed for other diseases like anti‒epileptics drugs (phenytoin), antihypertensive (diazoxide), topical corticosteroids. Such few drugs are available in the marketplace for alopecia treatment.
Current therapies within the alopecia treatment:
Management of patients with alopecia may be challenging as a variety of risk factors and mechanisms are involved in its etiology. Here are some medicines that are used for the treatment of baldness:
● Minoxidil (Rogaine, Headway)
● Finasteride is a specific inhibitor of type 2‒5 alpha reductase.
● Zinc inhibits 5a reductase enzyme.
● Skinoren/Azelaic Acid Potent inhibitor of 5 alpha reductase.
● Ketoconazole (Nizoral): Antiandrogenic effect causes reduction in testosterone and other androgens by adrenal.
● Prezatide copper (Lamin) it's the copper binding peptide.
● Copper chloride Androgen inhibitor of 5alpha reductase.
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