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Steel Bite Pro

Mark Haddon wrote a marvelous book that became a bestseller and won both the Whitbread Book of the Year and Whitbread Novel awards. It was said that Mark Haddon himself exclaimed, “Who on Earth would want to read about a fifteen-year-old boy with a disability?,” while he was making this book. Little did he know that it was exactly the fifteen-year-old boy with a disability that made his book stand out, win awards and become a bestseller. The book is called, “The Curious Incident Of The Dog In The Night-Time and the boy is Christopher.” Christopher is an autistic-savant. He can name all the countries in the world and their capitals. He has a photographic memory and a genius in math and science. Despite of his unusual intelligence, he cannot imagine, understand figures of speech and relate to jokes. He also does not like places with a lot of people and people touching him. People who are autistic-savants exhibit both characteristics common among those with autism and those with Savant Syndrome. Autism is one developmental disorder among the group of Autism Spectrum Disorders. This condition is mainly characterized by impairment in socialization, imagination and communication. Savant Syndrome is characterized by very low general intelligence but extraordinary narrow intelligence usually in the fields of mathematics, music, art and memorization. In the story, Christopher’s parents are separated. His mother decided to leave Christopher and his father because she cannot cope anymore with the demands of having an autistic child. Parents who take care of special children such as those with autism may probably have a higher stress level compared to most parents. This is mainly because their children have special demands, unusual behaviors and different abilities compared to other kids of the same age. These children will most likely find it difficult to communicate, thus, resulting to unusual reactions. An example of this is when an autistic child cries for no apparent reason and begins hitting himself or herself. Most likely, something has caused him or her to feel upset but cannot convey what it is because he or she does not know how. Some autistic children with sensory integration problems may either be hypersensitive or hyposensitive to touch, pressure, movement and sound. They will show certain behaviors that are sometimes difficult to understand such as avoidance of certain types of food and drinks, pinching or hitting, repetitive movements and screaming. Some of them can also exhibit strong adherence to certain routines and fear of new places or people. To accommodate the needs and cope with the behaviors of these children is not easy and, therefore, can result to a lot of stress. Autism can greatly limit a child’s world. They thrive in security and anything they perceive as a threat to their security should be avoided. However, a lot of factors, situations and demands of society make them insecure and being forced to deal with these makes them very anxious most of the time. Unconsciously and unintentionally, children with autism have a constant feeling of anxiety to anything that is new or foreign to their understanding. Just like in the book, when Christopher had to go beyond the area of the town that is familiar with him, he felt physically sick and afraid. Unlike most children, those with autism cannot easily adapt to new environment or situations. The process of learning to understand and accept what is previously unknown to them results to a higher level of anxiety. Despite what seems to be a difficult task of adapting and coping with autistic children, a lot has already been studied and published regarding proper management that will not only lessen the children’s anxiety but also their parents’ stress. Certain methods such as Cognitive Behavior Modification, Behavior Modification Techniques and Environmental Modification Techniques had been proven effective in changing the inappropriate behaviors and improving the learning skills of children with autism. Some, having compounding conditions other than autism,

may need additional treatment as advised by the doctors. Autistic children who also have manic depression due to their unhappiness with being involuntarily trapped in their self-protecting behaviors may need more therapy than what was mentioned earlier. Consulting a psychiatrist is highly advisable in this situation and other medications may be prescribed. Christopher’s story ended with him being able to overcome challenges that have caused him too much anxiety and his mother deciding to return to take care of him. Just like in this fictional novel, the same can be achieved in real life in terms of dealing with stress and anxiety among families who need to cope with the condition. Through proper management, medication or treatment, stress and anxiety among parents and autistic children can be addressed effectively.

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Back Pain SOS

It can be frustrating and confusing to find out what really works for a man’s prostate health. In this article I’ve summarized some of the major guidelines and recommendations you should know. And if you’ve found something that has really worked for you, which you have verified through trial and observation, please let me know. I’d like to be able to share it with others. First, read the following list of helpful hints related to improved prostate health and benign prostate enlargement. 1. Urinary tract infections (UTI’s) are mostly related to an enlarged prostate. Candida and infections like prostatitis are also related. Candida is a common and insidious condition you should be sure to eliminate. At my website I have a simple self-test for candida. 2. Do pelvic exercises to increase circulation by tightening your pelvic muscles intentionally at least 100 times a day. Raise your awareness of the inner world of your pelvic area. Give separate consideration to your buttocks, lower abdominals, scrotum, urethra, and sphincter. 3. Use Prosperon to raise your testosterone level naturally. 4. Drink plenty of water, every day, to flush out your system. 5. Move to a low animal-protein and grain-rich diet, or some variation on the macrobiotic. 6. Keep your weight in check. 7. Keep a journal in order to track and recognize, as soon as possible, what is working for you, and what is not. Think about your symptoms for yourself; don’t just depend on your doctor! 8. Realize that hormones are hormones and vitamins are vitamins. When his PSA test results were too high, a friend decided to heal himself by doing an anti-parasite treatment. It did no harm, but your prostate has to do with hormones, and needs to be dealt with on this level. You can’t put fresh oil in your car when you’re out of gas and then wonder why your engine won’t work! 9. Visualize that you are much healthier and that your prostate and urethra function well. Approach your body with love, as it is part of your temple where the soul resides. ACCEPT . Melatonin: An excellent study done at Tel Aviv University showed that the melatonin receptors in the prostate could suppress prostate enlargement. Researchers found that an enlarged prostate is due to the imbalance of estrogen and testosterone that occurs as we age. They further noted that the excess estrogen also interferes with the normal metabolism of melatonin (J. Clin. Endoc. Metab. 82 (1997) p. 2535 – 41). Their advice then, is to take 1-3 mg. of melatonin supplement every night. (Stick with this dosage; as with most medicines, more is by no means better.) Take it ONLY in the darkness of night, in order not to interfere with the body’s natural production of melatonin before sunrise. Go to bed by ten o’clock also, to get a good night’s rest. Good luck

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Back Pain SOS

It can be frustrating and confusing to find out what really works for a man’s prostate health. In this article I’ve summarized some of the major guidelines and recommendations you should know. And if you’ve found something that has really worked for you, which you have verified through trial and observation, please let me know. I’d like to be able to share it with others. First, read the following list of helpful hints related to improved prostate health and benign prostate enlargement. 1. Urinary tract infections (UTI’s) are mostly related to an enlarged prostate. Candida and infections like prostatitis are also related. Candida is a common and insidious condition you should be sure to eliminate. At my website I have a simple self-test for candida. 2. Do pelvic exercises to increase circulation by tightening your pelvic muscles intentionally at least 100 times a day. Raise your awareness of the inner world of your pelvic area. Give separate consideration to your buttocks, lower abdominals, scrotum, urethra, and sphincter. 3. Use Prosperon to raise your testosterone level naturally. 4. Drink plenty of water, every day, to flush out your system. 5. Move to a low animal-protein and grain-rich diet, or some variation on the macrobiotic. 6. Keep your weight in check. 7. Keep a journal in order to track and recognize, as soon as possible, what is working for you, and what is not. Think about your symptoms for yourself; don’t just depend on your doctor! 8. Realize that hormones are hormones and vitamins are vitamins. When his PSA test results were too high, a friend decided to heal himself by doing an anti-parasite treatment. It did no harm, but your prostate has to do with hormones, and needs to be dealt with on this level. You can’t put fresh oil in your car when you’re out of gas and then wonder why your engine won’t work! 9. Visualize that you are much healthier and that your prostate and urethra function well. Approach your body with love, as it is part of your temple where the soul resides. ACCEPT . Melatonin: An excellent study done at Tel Aviv University showed that the melatonin receptors in the prostate could suppress prostate enlargement. Researchers found that an enlarged prostate is due to the imbalance of estrogen and testosterone that occurs as we age. They further noted that the excess estrogen also interferes with the normal metabolism of melatonin (J. Clin. Endoc. Metab. 82 (1997) p. 2535 – 41). Their advice then, is to take 1-3 mg. of melatonin supplement every night. (Stick with this dosage; as with most medicines, more is by no means better.) Take it ONLY in the darkness of night, in order not to interfere with the body’s natural production of melatonin before sunrise. Go to bed by ten o’clock also, to get a good night’s rest. Good luck

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The Ultimate Keto Meal Plan

As good as modern medical technology is, it can never save you from the problems caused by a life style that is unhealthy. Instead of getting a modern medical fix for every problem, it is far better to live in such a way that you will hardly ever fall ill. An ounce of prevention is certainly better than a pound of cure. Here are seven tips on how to live a long and healthy life. In addition, the same life style that helps you to avoid illness also helps you to lose weight. 1. Get Enough Exercise In the past people had to use their physical bodies in the course of their normal work. But today someone may get up, go to work in a car, then sit down, get up to go home in the car and when arriving at home, sit down again for the rest of the day. In such a life there is no physical labor. This physical inactivity is one of the main reasons for a host of diseases. Sport, running. walking and other things must be added to our life if our normal work does not require us to exert ourselves physically. I 2. Go to sleep when you feel sleepy This may sound simple, but many people stay up late even when their body is telling them that it is time to sleep. Yoga and Ayurvedic doctors also say that it is better to sleep in the night and be active during the day. However, people such as students will take coffee and stimulants to study late into the night. Others develop the habit of remaining active at night and sleeping during the day. While we can do this, it eventually takes a toll on health. Alternative health doctors say that this kind of unnatural living is one of the contributing factors in the causation of cancer and other diseases 3. Eat when you feel hungry This is also a simple idea, but once again we often go against the messages of the body. If you eat out of habit or due to social pressure at certain time of the day, even when you have no real appetite, then you will not digest your food properly. Acidity and indigestion begin, and this contributes to the likelihood of other more complex diseases taking root. Having an appetite is actually a sign of good health, but if you have no appetite you should wait a bit and then eat. (If you have no appetite even after awaiting a reasonable amount of time, then you should consult a doctor because something is wrong.) 4.Fast on a Regular, Systematic Basis If you would ask any person to work 365 days per year without any rest, they would complain and say that they must have some rest or else they will break down. But we have never bothered to ask or to think about our digestive organs which we compel to work day after day without a rest. They cannot protest the way a person would to his boss, but they do give us signals that they cannot work non-stop. When we ignore those signals and still compel them to work, those organs break down. That is why periodic fasting is necessary. Refrain from eating for one complete day. This gives a rest to your digestive organs and also helps in the elimination of wastes from your body. Regular fasting allows a person to gain extra time for intellectual or spiritual pursuits. Fasting is not for hermits in a cave, but is a sensible practice that anyone can practice. 5. Wash with cool water before going to bed As mentioned above, proper sleep is essential for the maintenance of health. If you wash your important motor and sensory organs (hands, arms, eyes, legs, mouth, genitals) before sleep using cool water, this will relax you and prepare you for deep sleep. 6. Perform meditation on a regular basis Your body is linked to your mind. Many of the diseases of this era are psychosomatic. Stress and anxiety take their toll on our physical health. Meditation is a mental exercise which, among other things, allows you to detach yourself from the worries of life. Learn a simple technique and do it regularly. 7. Get up early every day Once again the old proverb, “Early to bed, early to rise makes a person healthy, wealthy and wise.” I don’t know if it will make you wealthy, but it will certainly make you healthy. Your body needs just enough sleep, not too much and not too little. Follow these tips and you can’t go wrong.

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Meticore

Actin is a ubiquitous protein involved in the formation of filaments that are major components of the cytoskeleton. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments which are part of the contractile apparatus in muscle cells. It is the most abundant protein in the typical eukaryotic cell, accounting for about 15% in some cell types. The protein is highly conserved, and forms a huge variety of structure in cells in concert with a huge numbers of actin binding proteins. The actin filaments interact with myosin to produce a sliding effect, which is the basis of muscular contraction and many aspects of cell motility, including cytokinesis. The individual subunits of actin are known as globular actin (G-actin) that assembles into long filamentous polymers called F-actin. Two parallel F-actin strands twist around each other in a helical formation, giving rise to microfilaments of the cytoskeleton. Microfilaments measure approximately 7 nm in diameter with a loop of the helix repeating every 37nm. Each actin protomer binds one molecule of ATP and has one high affinity site for either calcium or magnesium ions, as well as several low affinity sites. It exists as a monomer in low salt concentrations, but filaments form rapidly as salt concentration rises, with the consequent hydrolysis of ATP. Actin from many sources forms a tight complex with deoxyribonuclease (DNase I) although the significance of this is still unknown. The formation of this complex results in the inhibition of DNase I activity, and actin loses its ability to polymerise. It has been shown that an ATPase domain of actin shares similarity with ATPase domains of hexokinase and hsp70 proteins. In vertebrates there are three groups of actin isoforms: alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. MreB, a major component of the bacterial cytoskeleton, exhibits high structural homology to its eukaryotic counterpart actin. Further it has been suggested that members of the Rho family of small guanosine triphosphatases have emerged as key regulators of the actin cytoskeleton, and through their interaction with multiple target proteins, they ensure coordinated control of other cellular activities such as gene transcription and adhesion.

Reference: 

1. Actin isoforms. Curr Opin Cell Biol. 1993 Feb;5(1):48-55 Herman IM

2. The assembly of MreB, a prokaryotic homolog of actin. The assembly of MreB, a prokaryotic homolog of actin. J Biol Chem. 2005 Jan 28;280(4):2628-35. Epub 2004 Nov 16

3. Rho GTPases and the Actin Cytoskeleton Science 23 January 1998:

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