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Best Web Portal Development Services
web portal development company in chennai
At Apple Infoway, we can ensure about helping you with the most effective solutions to accomplish your organizational goals.
WEB PORTAL DEVELOPMENT COMPANY IN CHENNAI
We maintain the lowest price-quality relation in our services in the market.
At Apple Infoway Pvt Ltd, we can ensure about helping you with the most effective solutions to accomplish your organizational goals. Web Portal Development Company In Chennai of Technologies are engrained with expertise and experience. Web portal development Services in chennai involves proficiency at many levels whether it is architectonics design, Database Planning, Graphical User Interface design, and coding. Web Portals are the best means of establishing your existence determinedly on the web.
Our Web portal development company in chennai supply you with down to earth solutions that can upgrade your business in line with your responsibility and aim. A portal well executed, creates a brand for its owner and develops into a gateway for the cyberspace users seamless.
Web portal development service in chennai revolves around developing all-inclusive web application connected with third-party(mediator) Application Programming Interface.The developers today use the Web strategies and quick fixes to develop web portal which includes bilateral tools like discussion forums, blogs, real-time chat, rating tools, polls, videos and so on.
WHY APPLE INFOWAY PVT LTD ?
“Unite this world into one”
Apple Infoway Pvt Ltd is an Information Technology Company in India establishing its platform’s on Internet-related services. Services like Business Process Management, Customer Relation Management, Enterprise Resource Planning, Digital Marketing, Job Portal, Web Design & Development, Search Engine Optimization, Social Media Optimization, Search Engine Marketing and Social Media Marketing.
Our Vision is to be present "high esteemed and excellence based software" provided to our clients.
At Apple Infoway Pvt Ltd, We mingle together with everyone for innovative ideas for each and every project and well, results are way beyond exception. The main motto of Apple Infoway Pvt Ltd is “Unite this world into one”. Apple Infoway Pvt Ltd was started in late 2016. Since then Apple Infoway Pvt Ltd have always been preaching employees about “union” which is and always has been Apple Inofway Pvt Ltd main secret on winning in projects handled by us. We have started our journey in late 2016 but we are popping up in our client’s list for our sheer dedication towards projects.
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OUR SERVICES
DEVELOPMENT
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Website Design
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ERP
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E-COMMERCE
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Textiles Shop
Pharmacy
Furniture
Gift Shop
Accessories
Jewellery
Fruits Shop
Sea Foods
Restaurant
Book Shop
Electrical
Tools Shop
Foot Wear
MARKETING
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SEO
SMM
SEM
SMO
ERP
Branding
IOS & ANDROID APPS
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Pharmacy
Electrical
Gift Shop
Accessories
Jewellery
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Fruits Shop
Tools Shop
Sea Foods
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Furniture
BEST DEVELOPMENT COMPANY IN CHENNAI
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BPM on Apple Infoway Pvt Ltd is a daily job by any employee on premises. BPM is supervising and considering the processes present in an organization. BPM technique is tried in tragic situation to make sure mechanism is dynamic & adequate, that results in admirable and more cost effective organization.
WEB PORTAL DEVELOPMENT COMPANY IN CHENNAI
As the fellow companies collaborated with Apple Infoway Pvt Ltd say our area of expertise is definitely Business Process Management & Customer Relation Management. Now, we got products exhibiting our collaboration with BPM & CRM. Products, Software’s it’s the way you arrange them right after experiencing it. Our multiple CRM is equal to BPM.
Our CRM performs almost on all places covering each and every space fill able with our technology. Apple Infoway Pvt Ltd CRM covers hospital, Malls, Colleges, Schools, Information Technology, Distribution, Construction, Protection, Shipping and Manufacturing.
OUR SERVICES
SOCIAL MEDIA MARKETING
360° social media marketing and branding to make sure brand stands out from the rest
360° 360° social media marketing and branding to make sure brand stands out from the restsocial media marketing and branding to make sure brand stands out from the rest
FACEBOOK, TWITTER, LINKEDIN ADS
Create and manage social media Ads on Facebook, twitter and Linkedin that reach targeted potential customers around the world
CONTENT MARKETING & OPTIMIZATION
Content is the King when it comes o SEO and social media marketing. Content is the most important factor in digital marketing. We create and optimize content for the web
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SOCIAL MEDIA MARKETING
360° social media marketing and branding to make sure brand stands out from the rest
FACEBOOK, TWITTER, LINKEDIN ADS
Create and manage social media Ads on Facebook, twitter and Linkedin that reach targeted potential customers around the world
CONTENT MARKETING & OPTIMIZATION
Content is the King when it comes o SEO and social media marketing. Content is the most important factor in digital
marketing. We create and optimize content for the web
DESTINY OF DESIGNING
Search Engine Optimization
Business in 20th century is a crucial one but, Apple Infoway Pvt Ltd is a reputed professional SEO company in Chennai.
Business Process Management
Business process management is about the people to utilize the model, introduces the schemes and abundance of project taken place by the clients.
Web Development
Providing a Website design and developing it is a dedicated service to our potential clients is Apple Infoway.
DESIGNING
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Web Designing
Web Maintenance
Website Redesigning
Innovative Designing
Multimedia Sites
Corporate Web Designing
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Multi Language Websites
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Content Writing
We are here to support for u !!
EMAIL: [email protected]
PHONE NO: +91 - 93800 37777
+91 - 90873 22777
+91 - 90872 99777
+91 - 63815 20894
044 - 25280009
WEBSITE: https://appleinfoway.com/
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CABOZANTINIB 60MG [Cabometyx 60mg]
DESCRIPTION
Cabometyx 60mg
Cabometyx 60mg is a prescription medicine required to treat people with medullary thyroid cancer (MTC) which has spread to other parts of the body known as metastatic MTC.
Cabometyx 60mg is highly protein bound and there is a hypothetical risk that it will displace combination withwarfarin, so INR monitoring is recommended.
Cabometyx 60mg is not known if using in childrensafe and effective.
INDICATION
Cabometyx 60mg
Cabometyx 60mg tablet is Indicated for following conditions;
The treatment of Metastatic medullary thyroid cancer
The treatment of Advanced renal cell carcinoma (RCC) who have getting before anti-angiogenic therapy.
The treatment of Hepatocellular cancer who have previously received sorafenib.
MECHANISM OF ACTION
Cabometyx 60mg
Cabozantinib is also known as targeted therapy whichaims and attach to the tyrosine kinase receptors and prohibits the activity of multiple tyrosine kinases, contains RET, MET, and VEGF on the surface of the cell.
By connecting to these receptors, Cabozantinib stops important pathways whichdevelop cell division.
PROPERTIES
Ingredients : Cabozantinib
Strength : 60mg
Package : 30 tablets
ADME
Maximum plasma concentration is observed in 2-5 hours
Human serum protein bounding of Cabometyx is ≥ 99.7%
Mostly metabolized by CYP3A4 and minorly by CYP2C9.
The drug excreted mostly via feces 54 % and in urine 27% and half-life is 55 hours.
DOSAGE MANAGEMENT
Cabometyx 60mg
Do not substitute Cabometyx tablets with Cabozantinib capsules.
The prescribed dose of Cabometyx is 60 mg.
Administration Cabometyx is without food.
Tell the patients don’t not havefood for at least 2 hours before and 1 hour after taking cabometyx.
Continue the treatment until patient no longer experiences clinical benefit or experiences unacceptable toxicity.
Swallow Cabometyx tablets whole. Do not crush Cabometyx tablets.
PRECAUTIONS
Cabometyx 60mg
• Interrupt the Cabometyx 60mg in patients who develop an acute myocardial infarction, cerebral infarction, or any other clinically significant arterial thromboembolic complication.
• Interrupt the Cabometyx 60mg for patient if have severe hypertension that cannot be controlled with anti-hypertensive therapy.
• Checkthe patients for symptoms of perforations and fistulas, included abscess. discontinueCabometyx 20mg in patients who experience a perforation or a fistula.
• Avoid administration Cabometyx 60mg tablet to patients with a present history of patients with haemorrhage or haemoptysis.
• Advice pregnant women aboutpossible risk to a foetus. Hence inform females of reproductive possible to use effective contraception during treatment with Cabometyx 60mg and for 4 months after the last dose.
SIDE EFFECTS
• GI perforations and fistulas
• Thrombotic events
• Hypertension and hypertensive crisis
• Diarrhea
• Palmar-plantar erythrodysesthesia
• Haemorrhage
• Reversible posterior leukoencephalopathy syndrome
• Weight loss
• Decreased appetite
• Nausea
• Fatigue
• Oral pain
• Neutropenia
• Low platelets
• Taste changes
• Hair colour changes
• High blood pressure
• Low potassium
• Hair loss
• Dizziness
• Joint pain
• Swallowing trouble
• Muscle spasms
• Dyspepsia (indigestion)
• Skin redness
• Reduced sodium
PREGNANCY
Pregnancy Category is D: Based on studies of animal and mechanism of action, Cabometyx 60mg will cause risk to fetus when given to pregnant women.
Avoid pregnancy while on treatment with Cabometyx 60mg.
LACTATION
Advise the women not to breastfed to infants while on treatment with Cabometyx 60mg drugs because of possible risk to the fetus.
STORAGE
Store the drug at 20°C to 25°C
Keep away from the children resistances
CONTACT US
PHONE NO:
+91-9940472902
EMAIL:
WEBSITE
https://millionpharma.com/cabozantinib-60mg.php
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seo company chennai
LOCAL SEO
seo company chennai
Local SEO, differs in because it is concentrating on optimizing a commerce wiredexistence so that its web pages will be advertised by search engines when users enter local searches for its commodity or utility. Local search engine optimization is a comparable to SEO (seo company chennai) that it is also a process stirring the clarity of a website or a web page in a web search engine's unpaid results (SERP- search engine results page) usuallysignify to as "essential", "organic", or "secure" results. In common, the higher ranked on the search results page and more usuallya site come into sight in the search results list, the more visitors it will secure from the search engine's users; these visitors can then be convinced into customers
MORE ABOUT LOCAL SEO
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Google Maps
Google has added a new Q&A features to Google Maps allowing users to submit questions to owners and admit these to respond.
The Birth Of Local SEO
Local Search Results
Fake Reviews
LOCAL RANKING ACCORDING TO GOOGLE
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Eminence, purpose, and distance are the three main precedent Google claims to use in its algorithms to show results that best match a user's objection. Eminence reflects how well-known is a place in the offline world. An important museum or store, for example, will be given more Eminence. Google also uses data obtained on the web to assess Eminence such as review counts, links, articles. Purposeattribute to Google's algorithms effort to surface the listings that best match the user's query.
RANKING FACTORS
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Local Online Marketing : Major search engines have algorithms that regulate which local businesses rank in local search. In 2016, a study using statistical analysis assessed how and why business ranked in the Local Packs and identified positive equivalence between local rankings and 100+ ranking factors. Although the study can’t stimulateGoogle’s algorithm, it did deliver several attractive findings: Back-links showed the most important equivalence (and also Google’s Toolbar PageRank, indicating that older links are an advantage because the Toolbar has not been updated in a long time). Sites with more content (hence more keywords) contribute to fare better (as expected). Reviews on GMB also were found to strongly compare with high rankings. Other GMB factors, like the presence of photos and having a verified GMB page with opening hours, showed a positive compare (with ranking) albeit not as important as reviews. The quality of excerpt such as a low number of duplicates, consistency and also a fair number of excerpts, involve for a business to show in Local Packs. However, within the pack, citations did not dominate their ranking: “excerpts appear to be foundation but not anambitious advantage." The authors were instead surprised that targeting elements (city & state) in the title of the GMB landing page did not have any impact on GMB rankings Design structured data is a ranking determinant. The addition of the 'Local Business' mark-ups will enable you to seo company chennaiadvertisesuitable information about your business to Google. This involve opening hours, address, founder, parent company information and much more. The number of reviews and overall star rating compare with higher rankings in the Google map pack results.
contact us
PHONE NO :+91- 93800 37777 +91 - 90873 22777 +91 - 90872 99777 +91 - 63815 20894 EMAIL :[email protected] WEBSITE :http://localseochennai.com/
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Seo company in chennai
seo company in chennai
Apple Infoway Pvt Ltd is a reputed professional SEO company in Chennai, Nowadays If you're planning to start a business whether it is a small or a big business you should establish your presence in internet, To start a business in this new generation doing SEO activities is a crucial one. SEO is widely used for to generate your business leads and conversion.
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Apple Infoway Pvt Ltd is a one of the SEO company in chennai offers best SEO servicesat affordable cost which is crucially helps to improve your business. In chennai we're the only seo service company offers the SEO service at this low cost.
Since we have an own digital marketing institute for training, we make ourstudents to work for
our client's projects so that's the reason how we can give our service at this low amount, In quality wise we offers best service by providing complete knownledge onpage and offpage seo optimization techniques, and we takes short time to complete our client projects since we have an huge number of people those who works for SEO.
Key Advantages of a Website for Business:
Less Expensive
Better Relationship
Advertising
Increase Customers
Easy Accessibility
Increase Sales
Long Term Clients
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ADVANTAGES & BENEFITS OF SEO :
Drive quality visitors to your website and increase sales dramatically
Lower customer acquisition cost in comparison to other advertising and marketing channels
Generate new sales leads
Build brand awareness
HOW SEO CAN IMPROVE YOUR BUSINESS
Apple Infoway Pvt Ltd isn’t a company that offers you just monthly SEO reports, it offers results
Single point of contact and a personal touch that helps us relate better to your business
We offers you the best SEO services & reports in simple layman language
What are the things we focusing to grow your business in digital platform
While work for our client's business apart from SEO we also concentrate on Social medial optimization(SMO), Social media marketing(SMM), Analytics, Link building, and SEO content creation experts and professional on hand. In our SEO service company in chennai we offer high end SEO service at low of costWe have been authorized as the Best SEO company in Chennai.
TYPES OF SEO SERVICES
ONPAGE Optimization
OFFPAGE Optimization
ONPAGE OPTIMIZATION
OnPage Optimization (Process) refers to all measures that can be taken directly within the website in order to improve its position in the search rankings of the website. Examples of this include measures to optimize the content or improve the meta description and title tags.
Apple Infoways Pvt Ltd SEO analysts are strong in ON page activities. Our SEO ON page activities consist of Keyword Analysis & Research, Meta tag Optimizations, Robots, Site map integration, URL Optmization, Error Code Optimization, Analytiss and much more
OFF PAGE OPTIMIZATION
Off-page Optimization SEO activities is as important as the on-page SEO. Once you are done with your on page SEO, you must pay attention to the SEO Off-page optimization for better results in the search engine rankings. Apple Infoways Pvt Ltd SEO analysts are strong in Link building activities. Our SEO off page activities consist of article submission, blog posting and commenting, infographic submission, business listing, forum submission, video sharing, image sharing, ppt sharing, profile creation, guest posting, Q and A submission, bookmarking, classified submission and more
OUR SEO Techniques
OFF-PAGE
Strong quality link building
Local listing
Business Directories
Article Submissions
Articles
Web 2.0
ON-PAGE
Site Checkup
Page optimization
Image optimization
Language Tag
Content Creation
Optimization
Sitemap & robots.txt creation
Broken links checks
xHTML validation
Social Media Strategies
Blog Submission
Guest Posting
Videos Submissions
Forum Posting
Updates and newfeeds
Launching Campaigns
CONTACT US
MAIL ID : [email protected]
PHONE NO : +91 - 93800 37777
+91 - 90873 22777
+91 - 89399 95548
+91 - 63815 20894
044 - 25280009
WEBSITE :https://appleinfoway.com/best-seo-company-chennai.php#
https://appleinfoway.com/
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Lenvatinib 10mg capsules | Lenvatinib | Millionpharma
DESCRIPTION
Lenvatinib10mg
Lenvatinib10mg is a multi-kinase inhibitor and antineoplastic agents. It is a type of targeted treatment which target the specific cancer cells and hence reduces side effects caused by affected cells.
Lenvatinib10mg tablet inhibits the protein which promotes cell division by preventing the cancer cell development.
PRESCRIBED FOR
Lenvatinib10mg
•In adult,Lenvatinib 10mg is indicated for the treatment of metastatic, progressive, radioactive Differentiated Thyroid cancer. • •Lenvatinib10mg in combination with everolimus is indicated in patients for the treatment of advance Renal Cell Carcinoma following treatment before anti-angiogenic therapy.
•Lenvatinib 10mg tablet is also indicated for the first line treatment in patients suffering with unresectable hepatocellular carcinoma.
MECHANISM OF ACTION
•Lenvatinib is a tyrosine kinase inhibitor which has shown mainly anti-angiogenic properties, and direct prevention of malignant developed was also observed inside the models. Lenvatinibwhich selectively prevents the kinase functions of vascular endothelial growth factor receptors 1(FLT1), 2 (KDR), 3 (FLT4).
•Although not been studied directly with Lenvatinib 10mg, the mechanism of action (MOA) for High blood pressure is hypothesizing to be resolve by the prevention of VEGFR2 in vascular endothelial cells.
Same as the, the action for proteinuria is hypothesizing to be interfere with down regulation of VEGFR1 and VEGFR2 in the cell of bowman’s capsules of the glomerulus.
Lenvatinib10mg
PROPERTIES
•Ingredients : Lenvatinib
•Strength : 10mg
•Package : Pack of 20 Capsules.
ADME
•Absorption:
Time to high plasma concentration is 1-4 hours post dose. Effect with food is low to the extent Lenvatinib10mg of absorption.
• Distribution:
bounding of Human plasma proteins is 98% to 99%.
•Metabolism:
Lenvatinib 10mg is primarily metabolized in CYP3A. Lenvatinib 10mg metabolic pathway is identified as enzymatic and non-enzymatic processes.
•Elimination:
eliminated via 64% feces and 25% urine.
DOSAGE MANAGEMENT
•The usual dose of Lenvatinib for the adult patients is 24mg and administer has two 10mg capsules and one 4mg capsule given orally, once daily taken with or without food.
The Lenvatinib tablet should continue until disease progression or until unacceptable toxicity occurs.
•Take Lenvatinib 10mg tablet at the same time.
Patients with severe renal or hepatic impairment the dose is 14mg administer once daily orally.
•OVERDOSE:
Lenvatinib is not expected to be dialyzable because of maximum plasma protein binding and if the dose getting of Lenvatinib 10mg orally then causes death due to multiorgan dysfunction occurred in the patients.
PRECAUTIONS
•Blood pressure may increase while treatment with Lenvatinib 4mg. Your doctor will preferably check your blood pressure during your treatment.
•Inform the doctor if you are allergic to Lenvatinib 10mg, any other regimens, or any of the ingredients in Lenvatinib 10mg capsules. Other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may to change the doses of your drugs or guide carefully for adverse reaction.
Lenvatinib10mg
• Inform doctor if you have or had seizures, hypertension, a stroke, a heart attack, , especially those due to blood clots, a fistula, a tear in the wall of your GIT, QT interval prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death), low levels of Ca, K or Mg in your blood, bleeding problems, or cardiac, renal, or hepatic disease.
•Take into the knowledge that Lenvatinib 10mg may reduce the fertility in men and women. It not means that you or your partner cannot become pregnant. Inform doctor before if you are pregnant or plan to become pregnant. After becoming pregnant, you should use birth control while treatment with Lenvatinib 10mg and for at least 2 weeks after your treatment, become pregnant during Lenvatinib therapy, call your doctor immediately. Lenvatinib 10mg may harm the fetus.
•Take into the knowledge that Lenvatinib 10mg may reduce the fertility in men and women. It not means that you or your partner cannot become pregnant. Inform doctor before if you are pregnant or plan to become pregnant. After becoming pregnant, you should use birth control while treatment with Lenvatinib 10mg and for at least 2 weeks after your treatment, become pregnant during Lenvatinib therapy, call your doctor immediately. Lenvatinib 10mg may harm the fetus.
•Inform the doctor if you are breastfeeding or plan to breastfeed. Avoid breastfeed during Lenvatinib 10mg treatment.
SIDE EFFECTS
Common side effects:
Tiredness
Peeling of skin on palms and sole of the feet
Constipation
Loss of appetite
Weight loss
Joint and muscle pain
Insomnia.
Serious side effects :
Shortness of breath
Chest pain
Pain in arm, back, neck or jaw
Seizures
Black, tarry or bloody stools
Heavy menstrual bleeding
Coughing up blood
Yellowing of the skin or eyes.
Common side effects:
Tiredness
Peeling of skin on palms and sole of the feet
Constipation
Loss of appetite
Weight loss
Joint and muscle pain
Insomnia.
•PREGNANCY
When administrated to pregnant, Lenvatinib 10mg drugs can cause harm to the fetal. There are no available human data related to drug associated risk. Advice pregnant women specific risk to fetus.
•LACTATION
Excretion in human milk is unknown. It’s not known that drug is present in human milk Because of the serious side effects in infants from the drug, Advice to avoid breast feeding during treatment with Lenvatinib 10mg.
STORAGE
Store at 25°C
Keep out of the children hands Discard the after-expiry date Dispense the drug only in original container
KEYWORDS:
Lenvatinib 10mg
Lenvatinib 10mgtablet
Lenvatinib
Lenvima 10mg
CONTACT US
•EMAIL: [email protected]
•PHONE NO: +91-9940472902
•WEBSITE: https://millionpharma.com/lenvatinib-10mg.php
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ERP SOFTWARE DEVELOPMENT COMPANY IN CHENNAI
WHAT DOES ERP STAND FOR
erp software development company in chennai
ERP stands for (or enterprise resource planning software) is an integrated system used by organizations to combine, organize and maintain the data necessary for operations. ERP software companies systems merge an organization’s key operations, including the manufacturing, distribution, financial, human resources and customer relations departments, into one software system. Selecting an ERP software package and implementing it correctly can be an extremely complex and intimidating process for many executives and project teams. When the ERP evaluation and implementation is performed correctly, ERP software can revitalize an organization by streamlining and synchronizing its separate departments into one unified software system. When these tasks are done without focus and solid planning, the ERP software project can have severe repercussions that negatively effect the organization for many years to come.
Enterprise resource planning (ERP) is business process management software that allows an organization to use a system of integrated applications to manage the business and automate many back office functions related to technology, services and human resources.
A business will typically use a combination of different modules to manage back-office activities and tasks including the following:
Distribution process management
Supply chain management
Services knowledge base
Configure prices
Improve accuracy of financial data
Facilitate better project planning
Automate the employee life-cycle
Standardize critical business procedures
Reduce redundant tasks
Assess business needs
Accounting and financial applications
Lower purchasing costs
Manage human resources and payroll
ERP IS AN ENTERPRISE APPLICATION
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ERP software is considered to be a type of enterprise application, that is software designed to be used by larger businesses and often requires dedicated teams to customize and analyze the data as like ERP analysts and to handle upgrades and deployment. In contrast, Small business ERP application are lightweight business management software solutions, often customized for a specific business industry or vertical.
ERP SOFTWARE MODULES EXPLAINED
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ERP software companies typically consists of multiple enterprise software modules that are individually purchased, based on what best meets the specific needs and technical capabilities of the organization. Each ERP system module is focused on one area of business processes, such as product development or marketing, by software development services. Some of the most common ERP system modules include those for product planning, material purchasing, inventory control, distribution, accounting, marketing, finance and HR.
CONTACT US
MAIL ID : [email protected]
PHONE NO : +91 - 93800 37777
WEBSITE :
https://appleinfoway.com/best-online-management-software.php
https://appleinfoway.com/
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SEARCH ENGINE MARKETING-APPLE INFOWAY PVT LTD
sem company in chennai
A recent study has revealed that more 80% of people start their business in search engine marketing. Search Engine Marketing is the process of getting website traffic by promoting through ads on Search engines.
Search Engine Marketing (SEM) or PPC (Pay-Per-Click) is the model of paying search engines like Google and Bing to display your website’s advertisements. If you are looking for SEM Company in Chennai, Google promotion company in chennai Call : +91-93800 37777
WHY APPLE INFOWAY FOR SEM :
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We Maximize the leads with lowest cost
Transparent Cost
Faster Turnaround
Dedicated Client relationship manager
WHAT IS SEARCH ENGINE MARKETING ?
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Search engine marketing (SEM) is the transparent way to reach your target audience, who are ready to buy. Researches made to prove that buyers circle doing online searches about 90%.
WHICH OF THE FOLLOWING IS A BENEFIT OF SEARCH ENGINE MARKETING (SEM)?
SEM and SEO both are used to increase traffic and purchase as well too. SEO takes time, while search engine marketing process quickly to reach audience.Following are the sem analysis report showing benefits in servicing
Geo targeting
PPC services
Brand awareness
Transparency
Tests quickly point to the right direction
OUR SEM PROCESS :
Identify the Best and Unique Keywords that Converts
Landing Page Optimization
Ad Copy with High CTR
PPC Bid Management
Our first and foremost task is keyword selection. Our Search Engine Marketing consultant search for relevant keywords that suits your content and we make sure that the most searched unique keywords to rank higher in Google. After created a PPC ad page, we regularly analyze your campaign, properly testing your landing page that will improve your PPC campaigns results. A good PPC page will not only contain good keywords but it will also have unique attractive description with the repletion of the main keywords.
CONTACT US
MAIL ID :
PHONE NO : +91 - 93800 37777
+91 - 90873 22777
+91 - 89399 95548
+91 - 63815 20894
044 - 25280009
WEBSITE :https://appleinfoway.com/search-engine-marketing-company-chennai.php
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TWITTER MARKETING ADS COMPANY IN CHENNAI
twitter marketing company in chennai
Unlike any other marketing on social media, Twitter marketing is very challenging and needs dedicated time to maintain the account. Everyday people tend to update thousands and millions of tweets on different topics and issues. In these huge amounts of tweets your Twitter marketing will fade within the crowd.
Advertisements on twitter can prove to bring great success to your business if it is done in an appropriate and pre-planned manner. Twitter ads will help you to build up your brand using promotions and advertisements. Your ads will pop up in front of the users who search for your brand or any other relevant brands.
Twitter advertisements can be worked in two different ways; Twitter promote mode and Twitter ads mode. Both the modes are not much expensive and each has their own advantages and disadvantages. In order to work on the ads we need better and strong knowledge about the working modes.
twitter marketing company in chennai
Promoted Mode
You can promote your account and tweets by paying a fixed amount monthly to twitter for promoting you ads. The advertiser can use promoted mode to build his/her business stronger. Promoted tweets will appear in front of the users who are your target audience. These tweets will also be retweeted like any other tweet. The only difference is it will be labeled with a tag saying promoted.
This will help you gain more followers who are looking forward to the service or product you offer. The advantage in this mode is you need not take much stress about reaching your targeted audience.
Twitter will help you to promote your account in order to reach the targeted audience. Your account will be displayed to the users who are interested in your content but unaware of you account. This is also known as Followers campaigns, this will gain you more potential followers.
The advertiser should create strong keywords if they want to gain audience and depending upon your keywords your ads will pop in to the users account. These advertisements will be shown as ‘suggested’
Few objectives will be offered to you for promoting your ads: App installs, followers, twitter engagement, promoted video views, website clicks or conversation, App re-engagements, In stream video views and awareness. Depending on your preferred objectives you ads will be promoted.
App installs : Installing your app can bring you more audience and you will know how strong you have build your brand through twitter. Here you want the users to install your app and you will have to pay for each installed app.
Followers : followers decides the success of your account, your main focus should be building strong followers who can take your brand forward by sharing or linking it in their account.
Twitter engagement : You want more people to get engaged in your tweets, this will help to build your ads stronger.
Promoted video views : If many number of people watch your videos it is obvious that it will grow in popularity and it will tend to go viral. This should also be your main motive when you upload a video or a video link in your twitter account. The number of viewers the number of followers, so understand the value of it and create interesting content.
App re-engagements : Installing the app is not sufficient; the user should go back and check the updates and products in it. It should be created and maintained in an interesting manner which will make the users to open and use your app frequently.
Website clicks or conversation : Every click counts in website, number of viewers and activities happens in your website matters.
In stream video views : Here you will create more attractive and trending video for few second at the beginning of the video. These ads will be more attractive and last only for few seconds. The advertiser can create unique ads with important content which is to be advertised.
Awareness : Every advertiser will wish to have maximum number of view for his tweets. As the number of users visiting the tweets increases, the awareness about your brand will increase. So, creating awareness should be considered as an essential objective.
Now let us know about promoted trends, suggested trends are famous all around the social media. Even in twitter, promoted trends goes viral on user’s timeline, on twitter app and on explore tab. These trends come as hashtags and it pops up at the trending section. Any twitters will pick up your hashtag and pin that to other twitter user. This will help you to promote your work and it can happen only with strong keywords. Promoting your ads in Twitter is a great way of marketing your brand or product. Twitter marketing and ads can bring in more users through which your content can get highlighted and your brand can gain popularity.
twitter marketing company in chennai
Twitter ads
It is all about creating a campaign with a motive to reach your goals with multiple advertisements. Your objectives and strong keywords can help your brand to reach large audience. Twitter ads will help you to reach your goal by letting your user name to pop on suggestions list.
Targeting the right audience is also an essential work to be considered while advertising your brand. Twitter helps you to target your audience by giving you the clear picture of the interests different users have. You can select your audience based on their gender, location, interests, activities and their preferred events.
Apart from this twitter provides you ‘Twitter Quick Promote’ option; this is to promote your own tweet. If you know what and why to tweet and which is to be promoted, then you need not think of any mode and just get in to Twitter Quick Promote to promote your tweets.
The only difference is your tweets will not get promoted easily as you have to spend lot of time and research in your promotions. Still, it is a good idea for the starters and small business who do not want to invest more in the Twitter marketing and ads.
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SMO Company in Chennai| Apple Infoway Pvt Ltd
smo company in chennai
SOCIAL MEDIA MARKETING SERVICES
Social Media Optimization service help you reach thousands of targeted audience in a short period of time with a moderate investment. Apply Infoway’s SMO services are help your business to grow and getting brand awareness in all social media platforms. Our social marketing experts make your business visible in social ad world.
Being one of the best social media marketing companies in Chennai, we understand the client’s requirements and offer end to end social media management service.
We use a variety of social networking platforms like Facebook, Twitter, Google +, Linkedin, Instagram, Snapchat, Youtube, Tumblr, Stumbleupon, Pinterest to increase your website traffic and increases revenue of your product or service.
smo company in chennai
How to become a social media manager
As to be a successful social media manager, have to follow certain things as first to know about your channels strength. Next to become an expert on your channels, involve to know about what your competitors doing for their channels promotion, set an aggressive goals and use analytics define your standards around social ad world. Among all other social media's facebook marketing is one among the best, try to involve more on facebook marketing
smo company in chennai
WHY APPLE INFOWAY FOR SMO :
We thoroughly audit your social presence.
Create social profiles in all social media platforms.
reating a unique and crating engaging content.
Track and give you analytics reports of all social profiles.
SOCIAL MEDIA MANAGER
As to be a social media manager, need everything to know about pros and cons involve in it, here be with that as follows.
WE RE HERE TO HELP U
PHONE NO: +91-93800 37777, +91-90873 22777
EMAIL: [email protected]
WEBSITE: https://appleinfoway.com/social-media-marketing-services-chennai.php
https://appleinfoway.com
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Lenvatinib 10mg capsules | Lenvatinib | Millionpharma
DESCRIPTION
Lenvatinib10mg
Lenvatinib10mg is a multi-kinase inhibitor and antineoplastic agents. It is a type of targeted treatment which target the specific cancer cells and hence reduces side effects caused by affected cells.
Lenvatinib10mg tablet inhibits the protein which promotes cell division by preventing the cancer cell development.
PRESCRIBED FOR
Lenvatinib10mg
•In adult,Lenvatinib 10mg is indicated for the treatment of metastatic, progressive, radioactive Differentiated Thyroid cancer. • •Lenvatinib10mg in combination with everolimus is indicated in patients for the treatment of advance Renal Cell Carcinoma following treatment before anti-angiogenic therapy.
•Lenvatinib 10mg tablet is also indicated for the first line treatment in patients suffering with unresectable hepatocellular carcinoma.
MECHANISM OF ACTION
•Lenvatinib is a tyrosine kinase inhibitor which has shown mainly anti-angiogenic properties, and direct prevention of malignant developed was also observed inside the models. Lenvatinibwhich selectively prevents the kinase functions of vascular endothelial growth factor receptors 1(FLT1), 2 (KDR), 3 (FLT4).
•Although not been studied directly with Lenvatinib 10mg, the mechanism of action (MOA) for High blood pressure is hypothesizing to be resolve by the prevention of VEGFR2 in vascular endothelial cells.
Same as the, the action for proteinuria is hypothesizing to be interfere with down regulation of VEGFR1 and VEGFR2 in the cell of bowman’s capsules of the glomerulus.
Lenvatinib10mg
PROPERTIES
•Ingredients : Lenvatinib
•Strength : 10mg
•Package : Pack of 20 Capsules.
ADME
•Absorption:
Time to high plasma concentration is 1-4 hours post dose. Effect with food is low to the extent Lenvatinib10mg of absorption.
• Distribution:
bounding of Human plasma proteins is 98% to 99%.
•Metabolism:
Lenvatinib 10mg is primarily metabolized in CYP3A. Lenvatinib 10mg metabolic pathway is identified as enzymatic and non-enzymatic processes.
•Elimination:
eliminated via 64% feces and 25% urine.
DOSAGE MANAGEMENT
•The usual dose of Lenvatinib for the adult patients is 24mg and administer has two 10mg capsules and one 4mg capsule given orally, once daily taken with or without food.
The Lenvatinib tablet should continue until disease progression or until unacceptable toxicity occurs.
•Take Lenvatinib 10mg tablet at the same time.
Patients with severe renal or hepatic impairment the dose is 14mg administer once daily orally.
•OVERDOSE:
Lenvatinib is not expected to be dialyzable because of maximum plasma protein binding and if the dose getting of Lenvatinib 10mg orally then causes death due to multiorgan dysfunction occurred in the patients.
PRECAUTIONS
•Blood pressure may increase while treatment with Lenvatinib 4mg. Your doctor will preferably check your blood pressure during your treatment.
•Inform the doctor if you are allergic to Lenvatinib 10mg, any other regimens, or any of the ingredients in Lenvatinib 10mg capsules. Other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may to change the doses of your drugs or guide carefully for adverse reaction.
Lenvatinib10mg
• Inform doctor if you have or had seizures, hypertension, a stroke, a heart attack, , especially those due to blood clots, a fistula, a tear in the wall of your GIT, QT interval prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death), low levels of Ca, K or Mg in your blood, bleeding problems, or cardiac, renal, or hepatic disease.
•Take into the knowledge that Lenvatinib 10mg may reduce the fertility in men and women. It not means that you or your partner cannot become pregnant. Inform doctor before if you are pregnant or plan to become pregnant. After becoming pregnant, you should use birth control while treatment with Lenvatinib 10mg and for at least 2 weeks after your treatment, become pregnant during Lenvatinib therapy, call your doctor immediately. Lenvatinib 10mg may harm the fetus.
•Take into the knowledge that Lenvatinib 10mg may reduce the fertility in men and women. It not means that you or your partner cannot become pregnant. Inform doctor before if you are pregnant or plan to become pregnant. After becoming pregnant, you should use birth control while treatment with Lenvatinib 10mg and for at least 2 weeks after your treatment, become pregnant during Lenvatinib therapy, call your doctor immediately. Lenvatinib 10mg may harm the fetus.
•Inform the doctor if you are breastfeeding or plan to breastfeed. Avoid breastfeed during Lenvatinib 10mg treatment.
SIDE EFFECTS
Common side effects:
Tiredness
Peeling of skin on palms and sole of the feet
Constipation
Loss of appetite
Weight loss
Joint and muscle pain
Insomnia.
Serious side effects :
Shortness of breath
Chest pain
Pain in arm, back, neck or jaw
Seizures
Black, tarry or bloody stools
Heavy menstrual bleeding
Coughing up blood
Yellowing of the skin or eyes.
Common side effects:
Tiredness
Peeling of skin on palms and sole of the feet
Constipation
Loss of appetite
Weight loss
Joint and muscle pain
Insomnia.
•PREGNANCY
When administrated to pregnant, Lenvatinib 10mg drugs can cause harm to the fetal. There are no available human data related to drug associated risk. Advice pregnant women specific risk to fetus.
•LACTATION
Excretion in human milk is unknown. It’s not known that drug is present in human milk Because of the serious side effects in infants from the drug, Advice to avoid breast feeding during treatment with Lenvatinib 10mg.
STORAGE
Store at 25°C
Keep out of the children hands Discard the after-expiry date Dispense the drug only in original container
KEYWORDS:
Lenvatinib 10mg
Lenvatinib 10mgtablet
Lenvatinib
Lenvima 10mg
CONTACT US
•EMAIL: [email protected]
•PHONE NO: +91-9940472902
•WEBSITE: https://millionpharma.com/lenvatinib-10mg.php
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Lenvatinib 4mg capsules | Lenvatinib | Millionpharma
DESCRIPTION
Lenvatinib 4mg
Lenvatinib 4mg is a multi-kinase inhibitor and antineoplastic agents. It is a type of targeted treatment which target the specific cancer cells and hence reduces side effects caused by affected cells.
Lenvatinib 4mg inhibits the protein which promotes cell division by preventing the cancer cell development.
PRESCRIBED FOR
In adult, Lenvatinib 4mg tablet is indicated for the treatment of metastatic, progressive, radioactive Differentiated Thyroid cancer.
Lenvatinib 4mg in combination with everolimus is indicated in patients for the treatment of advance Renal Cell Carcinoma following treatment before anti-angiogenic therapy.
Lenvatinib 4mg is also indicated for the first line treatment in patients suffering with unresectable hepatocellular carcinoma.
MECHANISM OF ACTION
Lenvatinib is a tyrosine kinase inhibitor which has shown mainly anti-angiogenic properties, and direct prevention of malignant developed was also observed inside the models. Lenvatinib which selectively prevents the kinase functions of vascular endothelial growth factor receptors 1(FLT1), 2 (KDR), 3 (FLT4).
Although not been studied directly with Lenvatinib, the mechanism of action (MOA) for High blood pressure is hypothesizing to be resolve by the prevention of VEGFR2 in vascular endothelial cells.
Same as the, the action for proteinuria is hypothesizing to be interfere with down regulation of VEGFR1 and VEGFR2 in the cell of bowman’s capsules of the glomerulus.
PROPERTIES
Ingredients : Lenvatinib
Strength : 4mg
Package : Pack of 20 Capsules
ADD ME
Absorption:
Time to high plasma concentration is 1-4 hours post dose. Effect with food is low to the extent Lenvatinib 4mg of absorption.
Distribution:
bounding of Human plasma proteins is 98% to 99%.
Metabolism:
Lenvatinib 4mg is primarily metabolized in CYP3A. Lenvatinib 4mg metabolic pathway is identified as enzymatic and non-enzymatic processes.
Elimination:
eliminated via 64% feces and 25% urine.
DOSAGE MANAGEMENT
Lenvatinib 4mg
The usual dose of Lenvatinib for the adult patients is 24mg and administer has two 10mg capsules and one 4mg capsule given orally, once daily taken with or without food.
The Lenvatinib tablet should continue until disease progression or until unacceptable toxicity occurs.
Take Lenvatinib tablet at the same time.
Patients with severe renal or hepatic impairment the dose is 14mg administer once daily orally.
OVERDOSE:
Lenvatinib is not expected to be dialyzable because of maximum plasma protein binding and if the dose getting of Lenvatinib 4mg orally then causes death due to multiorgan dysfunction occurred in the patients.
Inform doctor if you have or had seizures, hypertension, a stroke, a heart attack, , especially those due to blood clots, a fistula, a tear in the wall of your GIT, QT interval prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death), low levels of Ca, K or Mg in your blood, bleeding problems, or cardiac, renal, or hepatic disease.
Take into the knowledge that Lenvatinib 4mg may reduce the fertility in men and women. It not means that you or your partner cannot become pregnant. Inform doctor before if you are pregnant or plan to become pregnant. After becoming pregnant, you should use birth control while treatment with Lenvatinib 4mg and for at least 2 weeks after your treatment, become pregnant during Lenvatinib therapy, call your doctor immediately. Lenvatinib 4mg may harm the fetus.
Inform the doctor if you are breastfeeding or plan to breastfeed. Avoid breastfeed during Lenvatinib 4mg treatment
PRECAUTIONS
Lenvatinib 4mg
Blood pressure may increase while treatment with Lenvatinib 4mg tablet. Your doctor will preferably check your blood pressure during your treatment.
Inform the doctor if you are allergic to Lenvatinib 4mg, any other regimens, or any of the ingredients in Lenvatinib 4mg capsules.
Other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may to change the doses of your drugs or guide carefully for adverse reaction.
SIDE EFFECTS
Common side effects:
Tiredness
Peeling of skin on palms and sole of the feet
Constipation
Loss of appetite
Weight loss
Joint and muscle pain
Insomnia.
Serious side effects :
Shortness of breath
Chest pain
Pain in arm, back, neck or jaw
Seizures
Black, tarry or bloody stools
Heavy menstrual bleeding
Coughing up blood
Yellowing of the skin or eyes.
PREGNANCY
When administrated to pregnant, Lenvatinib 4mg drugs can cause harm to the fetal. There are no available human data related to drug associated risk. Advice pregnant women specific risk to fetus.
LACTATION
Excretion in human milk is unknown. It’s not known that drug is present in human milk Because of the serious side effects in infants from the drug, Advice to avoid breast feeding during treatment with Lenvatinib 4mg.
STORAGE
Store at 25°C
Keep out of the children hands Discard the after-expiry date Dispense the drug only in original container
KEYWORDS:
Lenvatinib 4mg capsules, Lenvatinib 4mg, Lenvatinib, Lenvima
CONTACT US
EMAIL: [email protected]
PHONE NO: +91-9940472902
WEBSITE: https://millionpharma.com/lenvatinib-4mg.php
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Revolade 50mg[Eltrombopag]
DESCRIPTION
Revolade 50mg
Eltrombopag is sold under the brand name Revolade and it is a man-made form of a protein that increases production of platelets (blood-clotting cells) in your body.
Revolade 50mg can reduces the risk of bleeding by increasing platelets in your blood.
Revolade 50mg tablet which is used asprescription drug under the guidance of the medical practioners
Revolade 50mg
INDICATION
Revolade 50mg isan anticancer medication which is;
Indicated for the treatment of patients having Severe aplastic Anemia
• First line treatment of severe aplastic Anemia
• Treatment of refractory severe aplastic Anemia
Indicated for the treatment to stimulate the growth and development of platelets in the bone marrow
Primarily indicated for the treatment of patients having reduced platelet counts due to chronic hepatitis C virus infection
MECHANISM OF ACTION
Revolade 50mg
Eltrombopag consist of class of drugs known as thrombopoietin (TPO) receptor agonists. A class of drugs is a group of medications which work in a same way.
Eltrombopag mechanism by raising cells in your bone marrow and causes these cells to make more platelets. This effect reduces your risk of bleeding.
PROPERTIES
Ingredients : Eltrombopag
Strength : 50mg
Package : 7 tablets in a strip
ADME
Absorption:
High plasma concentration is 2-6 hours
Distribution:
Maximum human plasma protein bounding is >99% and in blood plasma level is 50% to 79%
Metabolism:
generally metabolised via cleavage, oxidation and conjugation with glucuronic acid.
Elimination:
Revolade 50mg eliminated mainly via feces 59%, along with 31% via renally excreted
Revolade 50mg Half-life for healthy patients is 21-23 hours and idiopathic thrombocytopenic purpura is 26-35 hours.
DOSAGE MANAGEMENT
Revolade 50mg
• The usual dose for Chronic Hepatitis C-associated Thrombocytopenia is 25 mg PO qDay. Dose is managed in 25 mg accretion q2weeks PRN to attain target Plt needed to start/control antiviral therapy with pegylated interferon and ribavirin; not to exceed 100 mg/day
• Severe Aplastic Anemia :
1.First-line therapy :
When combination with standard immunosuppressive treatment, for patients with serious aplastic Anemia (SAA)
The usual dose for severe Aplastic Anemia: 150 mg PO qDay for 6 months
Avoid taking of more than starting dose; total duration is 6 months
2.Refractory SAA :
In this condition the drug given who fail to respond enough to at least 1 before immunosuppressive therapy
The usual dose for Refractory SAA: 50 mg PO qDay
• The recommended dose for Chronic Immune Thrombocytopenia is 50 mg PO qDay Adjust dose to manage and control platelet count (Plt) >50 x 10^9/L to reduce the risk of bleeding; not to exceed 75 mg/day
PRECAUTION
• The drug Revolade 50mg may have high risk of severe and probably life-threatening hepatotoxicity; monitor liver function before and during treatment
• While receiving the drug, if patient with hepatic impairment (Child-Pugh Class A, B, C) initiates therapy for first- line treatment of severe aplastic Anemia, reduce initial dose
• When treatment, If the patients have cataracts, do not use the drug due to the Revolade 50mg effects cataracts and make the condition worse.
• Avoid the Revolade 50mg while the patients have myelodysplastic syndrome (MDS), will increases the risk of death.
• While on treatment with drug Revolade then Portal vein thrombosis reported in patients with chronic liver disease.
SIDE EFFECTS
Common side effects of Revolade 50mg :
• Headache
• Cough
• Loss of appetite
• Flu
• Reduced red blood cells
• Diarrhoea
• Nausea
• Fever
• Weakness
Serious side effects of
Revolade 50mg
:
• Swelling of legs
• Abdomen swelling
• Confusion
• Chest pain
• Dyspnea
• Cloudy vision
• Urine in dark colour
• Yellowing of your skin
• Sensitivity to light
• Seeing circles around lights
PREGNANCY
Pregnancy category is C
Safety of drug during pregnancy is not established
LACTATION
During breast feeding, avoid using of drug Revolade 50mG
STORAGE
Store at room temperature 20°C and 25°C.
CONTACT US
EMAIL: [email protected]
PHONE NO: +91-9940472902
WEBSITE: https://millionpharma.com/eltrombopag- 50mg.php
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AVASTIN 100MG|BEVACIZUMAB
DESCRIPTION
Avastin 100mg
Bevacizumab is a drug sold under the name of Avastin 100mg(BEVACIZUMAB) and which is categorized as monoclonal anti-body & anti-angiogenesis.
When Avastin 100mg tablet concomitant use with human monoclonal antibody IgG1, that circumstance and prohibits the biological action of human vascular endothelial growth factor (VEGF).
USAGE:
Avastin 100mg is indicated for the treatment of some of the conditions like Metastatic colon or rectal cancer Non-squamous, non-small cell lung cancer Glioblastoma Metastatic renal cell cancer.
Metastatic cervical cancer Epithelial ovarian, fallopian tube or peritoneal cancer.
MECHANISM OF ACTION:
Avastin 100mg tablet comprises an active compound like Bevacizumab which binds to VEGF and avoid the communication of VEGF to its receptors like Flt-1 & KDR) present on the surface of the cells This interaction prevents endothelial cell multiplication and new blood vessel production occurs Hence in counts cessation of metastatic cancer cells development happens.
Avastin 100mg
PROPERTIES
Ingredients : Bevacizumab
Strength : 100mg/4ml
Package : 400mg of Bevacizumab containing vial
ADME PROPERTIES
Distribution
The volume of distribution is 2.9 (22%) L
Elimination
The Bevacizumab half life period is 20days (11 to 50days)
DOSAGE MANAGEMENT
KEY POINT
Avoid administration of Avastin 100mg tablet before at least 28 days following surgery and the wound is completely cured.
METASTATIC COLORECTAL CARCINOMA
Concomitant use with 5-fluorouracil based chemotherapy is the usual dosage of Avastin 100mg : While concomitant use with bolus IFL the dose is 5mg/kg of Avastin for every 2 weeks IV. While in combination with FOLFOX4 the dose is 10mg/kg of Avastin for every 2 weeks IV 5mg/kg IV Avastin for every 2 weeks or 7.5 mg/kg Avastin as IV every 3 weeks by concurrently used with fluoropyrimidine Irinotecan or fluoropyrimidine oxaliplatin based therapy.
Avastin 100mg
NON-SMALL CELL LUNG CANCER
While combining with carboplatin and paclitaxel : The Avastin 100mg tablet usual dosage is 15mg/kg IV for every 3 weeks by
Avastin 100mg
GLIOBLASTOMA
Avastin 100mg
For every 2 weeks : 10mg/kg of Avastin 100mg administered IV
METASTATIC CERVICAL CANCER
Avastin 100mg
Combining with paclitaxel and cisplatin or with paclitaxel and topotecan : The drug Avastin 100mg tablet usual dosage is 15mg/kg of Avastin 100mg given intravenously for every 3 weeks
METASTATIC RENAL CELL CANCER
Concurrent use with interferon alfa : The Avastin 100mg tablet usual dosage is 10mg/kg IV for every 2 weeks
Avastin 100mg
EPITHELIAL OVARIAN, FALLOPIAN TUBE OR PERITONEAL CANCER
Platinum opposing: Concurrent use with paclitaxel, pegylated liposomal doxorubicin or topotecan :The Avastin 100mg regular dosage is 10mg/kg of Avastin for every 2 weeks Or Combining with topotecan : The Avastin 100mg regular dosage 15mg/kg of Avastin 100mg given through IV for every 3 weeks Platinum responsive concomitant with carboplatin and paclitaxel for 6 to 8 cycles : The drug Avastinrecommended dosage of is 15mg/kg given IV for 3 weeks Combining with gemcitabine & carboplatin for 6 to 10 cycles : The Avastin 100mg tablet recommended dosage is 15mg/kg of Avastin given IV for 3 weeks.
Avastin 100mg
PREPARATION & ADMINISTRATION
Avastin 100mg tablet is intravenous solution At initial infusion: given IV infusion over 90 minutes Following infusions: give second infusion over 60 minutes, if tolerated Administer all following infusion over 30minutes Avastin 100mg IV infusion is prepared in aseptic condition Avastin 400mg containing 16ml solution whereas 100mg containing 4ml Avastin dilute into 100ml of 0.9% NS Do not dilute with dextrose solution Dispose the remaining portion of medicine which is left in a vial.
PRECAUTIONS
There are some complications occurred during treatment with Avastin , care should be taken Arterial thromboembolic events: cessation of treatment with Avastin 100mg tablet in patients who are suffered with severe ATE. Venous thromboembolic events: Toxicity Incidence should be detected; If severe condition therapy should be stopped.
Hemorrhage: While on Avastin 100mg treatment some Serious hemorrhages will occur like GI hemorrhage, hemoptysis, Hematemesis, CNS hemorrhage, nose bleeding & vaginal bleeding. Hence Discontinue the treatment. Hypertension: Bp is increased in patients who are receiving Avastin therapy, must be frequently check up with blood pressure and provided with alternative medication for correct the pressure. In hypertension crisis or encephalopathy should be discontinue the treatment.
Posterior reversible encephalopathy syndrome Embryo fetal toxicity occurs : During pregnancy condition Avastin 100mg is contraindicated which produce fetal harm. Ovarian failure: The patients who are receiving Avastin may have a chance of getting ovarian failure. Congestive heart failure: the drug combination with anthracycline based chemotherapy, treatment with Avastin 100mg tablet must not be used. Avastin treatment should be stopped while CHF occurs.
SIDE EFFECTS
Gastrointestinal perforation and fistulae Surgery and wound healing complication Hemorrhage Arterial thromboembolic events Venous thromboembolic events Hypertension Posterior reversible encephalopathy syndrome Renal injury & Proteinuria Infusion reactions Ovarian failure Congestive heart failure Neutropenia, mucosal inflammation, infection, neuropathy, Epistaxis, erythrodysaesthesia
Avastin 100mg
PREGNANCY & LACTATION:
Pregnancy category:
D While administrating Avastin 100mg in pregnant women, positive evidence on fetal risk depends on human studies but potential benefits by using the drug may have common risk against fetus.Avastin 100mg tablet is excreted into breast milk taking account on this, discussion should done on whether to discontinue the breast feeding or the drug. The drug is risky during mother breast feeding to their infants.
STORAGE
The drug stored at 2 to 8°C (36 to 46°F) Single use vial Dispose the left out vial under the guidance of pharmacists.
MISSED DOSE
The dose missed by patient should have the dose immediately before the next dose timing reaches, or leave the missed dose and continue the regular schedule. Remember do not have double dose at a time Please consult with doctor for further details.
CONTACT US
MAIL ID : [email protected] PHONE NO :+91-9940472902 WEBSITE :
https://millionpharma.com/bevacizumab.php
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Cabometyx 20mg tablet-MillionHealthPharma
DESCRIPTION
Cabometyx 20mg
Cabometyx 20mg is a prescription medicine required to treat people with medullary thyroid cancer (MTC) which has spread to other parts of the body known as metastatic MTC.
Cabometyx 20mg is highly protein bound and there is a hypothetical risk that it will displace combination withwarfarin, so INR monitoring is recommended.
Cabometyx 20mg is not known if using in childrensafe and effective.
INDICATION
Cabometyx 20mg is Indicated for following conditions;
The treatment of Metastatic medullary thyroid cancer
The treatment of Advanced renal cell carcinoma (RCC) who have getting before anti-angiogenic therapy.
The treatment of Hepatocellular cancer who have previously received sorafenib.
Cabometyx 20mg
MECHANISM OF ACTION
Cabozantinib is also known as targeted therapy whichaims and attach to the tyrosine kinase receptors and prohibits the activity of multiple tyrosine kinases, contains RET, MET, and VEGF on the surface of the cell.
By connecting to these receptors, Cabozantinib stops important pathways whichdevelop cell division.
Cabometyx 20mg
PROPERTIES
Ingredients : Cabozantinib
Strength : 20mg
Package : 30 tablets
ADME
Maximum plasma concentration is observed in 2-5 hours
Human serum protein bounding of Cabometyx is ≥ 99.7%
Mostly metabolized by CYP3A4 and minorly by CYP2C9.
The drug excreted mostly via feces 54 % and in urine 27% and half-life is 55 hours.
DOSAGE MANAGEMENT
Do not substitute Cabometyx tablets with Cabozantinib capsules.
The prescribed dose of Cabometyx is 60 mg.
Administration Cabometyx is without food.
Tell the patients don’t not havefood for at least 2 hours before and 1 hour after taking cabometyx.
Continue the treatment until patient no longer experiences clinical benefit or experiences unacceptable toxicity.
Swallow Cabometyx tablets whole. Do not crush Cabometyx tablets.
PRECAUTIONS
Cabometyx 20mg
• Interrupt the Cabometyx 20mg tablet in patients who develop an acute myocardial infarction, cerebral infarction, or any other clinically significant arterial thromboembolic complication.
• Interrupt the Cabometyx 20mg for patient if have severe hypertension that cannot be controlled with anti-hypertensive therapy.
• Checkthe patients for symptoms of perforations and fistulas, included abscess. discontinueCabometyx 20mg in patients who experience a perforation or a fistula.
• Avoid administration Cabometyx 20mg to patients with a present history of patients with haemorrhage or haemoptysis.
• Advice pregnant women aboutpossible risk to a foetus. Hence inform females of reproductive possible to use effective contraception during treatment with Cabometyx 20mg tablet and for 4 months after the last dose.
SIDE EFFECTS
The following side effects ofcabometyx 20mg :
• GI perforations and fistulas
• Thrombotic events
• Hypertension and hypertensive crisis
• Diarrhea
• Palmar-plantar erythrodysesthesia
• Haemorrhage
• Reversible posterior leukoencephalopathy syndrome
• Weight loss
• Decreased appetite
• Nausea
• Fatigue
• Oral pain
• Neutropenia
• Low platelets
• Taste changes
• Hair colour changes
• High blood pressure
• Low potassium
• Hair loss
• Dizziness
• Joint pain
• Swallowing trouble
• Muscle spasms
• Dyspepsia (indigestion)
• Skin redness
• Reduced sodium
PREGNANCY
Pregnancy Category is D: Based on studies of animal and mechanism of action, Cabometyx 20mg will cause risk to fetus when given to pregnant women.
Avoid pregnancy while on treatment with Cabometyx 20mg tablet .
LACTATION
Advise the women not to breastfed to infants while on treatment with Cabometyx 20mg drugs because of possible risk to the fetus.
STORAGE
Store the drug at 20°C to 25°C
Keep away from the children resistances
CONTACT US
PHONE NO:+91-9940472902
EMAIL:[email protected]
WEBSITE:https://millionpharma.com/cabozantinib-20mg.php
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TAGRISSO 40MG [OSIMERITINIB 40MG]
DESCRIPTION
Tagrisso 40mg
A Tagrisso 40mg tablet is containing an active substance known as Osimeritinib, which is formerly known as Mereletinib.
Tagrisso 40mg is considered as third generation medicine, which is available in tablet form.
Tagrisso 40mg is an inevitable, selectively deviated epidermal growth factor receptor prohibitor, containing anti-cancer activity.
The pharmacological category of Tagrisso 40mg is tyrosine kinase prohibitor.
INDICATION
Tagrisso 40mg
A Tagrisso 40mg tablet is widely indicated as first line therapy for advanced non-small cell lung cancer with EGFR mutation positive patients.
Tagrisso 40mg is also used for the treatment of patients affected with advanced EGFR T792M mutation positive NSCLC, disease has advanced on or after the tyrosine kinase inhibitor treatment.
MECHANISM OF ACTION
Tagrisso 40mg
Osimeritinib is similar in action when compared to other tyrosine kinase inhibitor drugs.
Osimeritinib is named tyrosine kinase inhibitor of epidermal development factor receptor which is available on the surface of tumor cells
Osimeritinib is non-reversibly converge with mutant type of EGFR at 9 folds than wild sort
Forbids EGFR sharpening changes exon 19 Del and L858R
Prompts denies transformed EGFR with T790M opposition transformation
At last, bring down action against wild kind EGFR
Tagrisso 40mg
PROPERTIES
Ingredients : Osimeritinib
Strength : 40mg
Package : 30 tablets in a carton
ADME
Absorption :
High plasma concentration time of Osimeritinib reaches within 6 hours
Distribution :
Volume of distribution 918L
Human Plasma protein bound to Osimeritinib is 95%
Metabolism :
The metabolism of Osimeritinib is occurs via oxidation.
The Two pharmacologically active metabolite of Osimeritinib are AZ7550 & AZ5104
Excretion :
The mean terminal half-life period 48 hours
Clearance value 14.3L/hr
68% of metabolite is excreted in feces; 14% through urine
2% of unchanged form of drug is eliminated
DOSAGE MANAGEMENT
The recommended dosage of Tagrisso tablet are, 80mg tablet should be taken as a single dose.
Tagrisso 40mg tablet should be administered with or without food.
If patient felt difficult to swallow the Tagrisso tablets as such, must disperse the tablet in 60ml of noncarbonated water and drink the solution immediately.
Tagrisso tablet do not break, crush or chew.
Interrupt the treatment during the conditions like;
Interstitial lung disease
QT prolongation
Symptomatic congestive heart failure
In pain management
Grade III or severe: discontinue the Tagrisso 40mg tablet for 3 weeks
Grade 0 to II: follow at 80mg or 40mg as a single dose
If no development in 3 weeks: Discontinue the therapy.
While co administration of Tagrisso with CYP3A4 inducers, the dosage of Tagrisso should be increased to 160mg as a single dose and followed by 80mg for 3 weeks after discontinuation of strong CYP3A4 inducers.
PRECAUTIONS
nterstitial lung disease:
To avoid this problem, withheld or stop the Tagrisso 40mg tablets.
Keratitis:
check the manifestation of keratitis regularly and provide supportive measures
Embryo fetal toxicity:
Tagrisso 40mg tablet required in pregnancy period causes fetal damage.
QTc extension:
Do not concurrent use of Tagrisso 40mg with drug prolong the QTc
Cardiomyopathy:
Periodic cardiac monitoring is assessed; in this condition stop the therapy.
SIDE EFFECTS
Tagrisso 40mg
The most common adverse effects occurred during the therapy;
Cardiomyopathy, QT prolongation, Interstitial lung disease, Keratitis.
Other common side effect :
Tagrisso 40mg
Diarrhea or constipation, Hyperglycemia, Hypomagnesemia, Hyponatremia, Elevation of AST & ALT, Stomatitis, Nausea, Vomiting, Rash, Nail toxicity, Pruritus, Dry skin, Headache, Cough, Dyspnea, Fatigue, Pyrexia, Loss of appetite, Respiratory tract infection, Lymphopenia,Thrombocytopenia, Anemia, Neutropenia.
PREGNANCY
Pregnancy category of Osimeritinib is not designate
While using Tagrisso 40mg tablet causes possible for fetal harm
LACTATION
Milk feeding should not be taken during lactation period.
STORAGE
The Tagrisso 40mg tablet is, stored at 25°C.
Keep the tablet carton from moisture, heat and light.
MISSED DOSE
In case of missed dose, do not take the missed dose and follow the regular dosing schedule.
CONTACT US
PHONE NO: +91-9940472902
EMAIL: [email protected]
WEBSITE: https://millionpharma.com/osimeritinib-40mg.php
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