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“People who have a creative side and do not live it out are most disagreeable clients. They make a mountain out of a molehill, fuss about unnecessary things, are too passionately in love with somebody who is not worth so much attention, and so on. There is a kind of floating charge of energy in them which is not attached to its right object and therefore tends to apply exaggerated dynamism to the wrong situation.The moment these people devote themselves to what is really important, the whole overcharge flows in the right direction, ceasing to heat up things not worth so much emotional attention.”

— Marie-Louise von Franz, Shadow and Evil in Fairy Tales

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Cuando te volveré a ver?

Martes

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“Listen to what is being preached today. Look at everyone around us. You’ve wondered why they suffer, why they seek happiness and never find it. If any man stopped and asked himself whether he’s ever held a truly personal desire, he’d find the answer. He’d see that all his wishes, his efforts, his dreams, his ambitions are motivated by other men. He’s not really struggling even for material wealth, but for the second-hander’s delusion—prestige. A stamp of approval, not his own. He can find no joy in the struggle and no joy when he has succeeded. He can’t say about a single thing: ‘This is what I wanted because I wanted it, not because it made my neighbors gape at me.’ Then he wonders why he’s unhappy. Every form of happiness is private. Our greatest moments are personal, self-motivated, not to be touched. The things which are sacred or precious to us are the things we withrdraw from promiscuous sharing. But now we are taught to throw everything within us into public light and common pawing.”

— Ayn Rand, The Fountainhead

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28.5

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Ver "Ex Machina - Tearing Up the Dance Floor Extended" en YouTube

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“Our impulses are being redirected. We are living in an artificially induced state of consciousness that resembles sleep(…) The poor and the underclass are growing. Racial justice and human rights are nonexistent. They have created a repressive society, and we are their unwitting accomplices. Their intention to rule rests with the annihilation of consciousness. We have been lulled into a trance. They have made us indifferent to ourselves, to others. We are focused only on our own gain. Please understand. They are safe as long as they are not discovered. That is their primary method of survival. Keep us asleep, keep us selfish, keep us sedated.”

— They Live, John Carpenter (via tired-of-earth)

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Perception study may explain promising depression therapy

Rather than constantly repainting a new canvas with a picture of the surrounding world each time it takes in information, the human brain appears to build a working model supported by predictions constantly checked and rechecked against the sights and sounds it already expects.

Researchers from the University of Wisconsin–Madison have demonstrated the top-down nature of this world view by disrupting it with tiny doses of an anesthetic drug called ketamine. Their study reveals the importance of a specific type of connection between brain cells and may also explain ketamine’s promise as a treatment for depression.

A bottom-up understanding of perception has been prevalent for decades and says that sensory information moves from lower-order parts of the brain to “higher” parts that use it to perform executive functions like focusing and planning. But the top-down approach has roots in the 19th century. Now called predictive coding, the idea is that the frontal lobe of the brain makes predictions about what will happen next based on learned associations.

“You come to expect that if you hear a bark, you will see a dog,” says Sounak Mohanta, a graduate student in the lab of UW–Madison psychology and neuroscience professor Yuri Saalmann. “We used those sorts of associations to show how predictions affect behavior.”

For their study, published recently in the Journal of Neuroscience, the researchers taught 32 volunteers associations that were completely new to them by playing them a three-syllable nonsense word and following it with a picture from an assortment of unique animal-like shapes called greebles.

Through feedback, the volunteers learned which sound was paired with which picture. The researchers then tested the volunteers by playing them a sound, showing them a picture, and asking the volunteers to say whether the pair matched. The researchers also mapped the patterns in volunteers’ brains specific to correct sound-shape pairs by recording electrical activity as the sounds and shapes appeared.

Once three of these associations were introduced, the predictive qualities of the sounds were skewed in the test subjects’ minds by making a paired greeble follow its matched sound 85 percent of the time, 50 percent of the time or 33 percent of the time.

“The stronger our listeners understood a sound was predictive of a certain shape, the quicker they could tell us if the shape we showed them matched the sound,” Saalmann says. “Their reaction times for the 50-percent-predictive sounds were much slower, and slower still for the least predictive sounds.”

After hearing the highly predictive sound, activity in the subjects’ frontal lobes would increase, sending a signal down to the sensory centers in the back of the brain and activating the brain cells, called neurons, that represent the anticipated shape. Then, when the shape appeared, those neurons would get even more active and would elicit speedier responses from the viewer.

Unless the study subjects were administered ketamine.

“This drug, ketamine, blocked that whole set of processes, every one of those steps,” Mohanta says.

Neurons communicate by passing chemical signals across tiny gaps between neighboring cells. Each type of signal has a transmitter and receptor. Ketamine interferes with one specific communication channel by blocking NMDA receptors, which are common on the neurons along the pathways from the frontal lobe to sensory centers. This blocks the signal.

After a tiny dose of ketamine — set by former UW­–Madison anesthesiologist Rob Sanders, now at the University of Sydney in Australia — the highly predictive sound caused different, much noisier and disorganized activity in the frontal lobe. The pathway through the brain that normally prepared sensory centers for the anticipated shape instead stayed relatively quiet. Reaction times for all shapes stretched out, making them more like reaction times for the least-predictive sounds.

“The priming signal is lost. The brain no longer benefits from the top-down predictions, and errors happen,” says Saalmann, whose work is supported by the National Institutes of Health. “This experiment Sounak designed means whatever your view on how perception comes together, you need to include the predictions in this feedback process as an important part of brain function.”

Poor predictions are a feature of disorders including depression and schizophrenia, in which they can erroneously convince someone the worst is bound to happen or lead to hallucinations. Ketamine has been shown to relieve depression-like symptoms in animal studies, and is being used for clinical studies of depression.

“Blocking the negative predictions that are prominent in depressed patients could be how ketamine helps,” Saalmann says.

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Meno male ci sono loro vah.

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Encontradas

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“Listen to what is being preached today. Look at everyone around us. You’ve wondered why they suffer, why they seek happiness and never find it. If any man stopped and asked himself whether he’s ever held a truly personal desire, he’d find the answer. He’d see that all his wishes, his efforts, his dreams, his ambitions are motivated by other men. He’s not really struggling even for material wealth, but for the second-hander’s delusion—prestige. A stamp of approval, not his own. He can find no joy in the struggle and no joy when he has succeeded. He can’t say about a single thing: ‘This is what I wanted because I wanted it, not because it made my neighbors gape at me.’ Then he wonders why he’s unhappy. Every form of happiness is private. Our greatest moments are personal, self-motivated, not to be touched. The things which are sacred or precious to us are the things we withrdraw from promiscuous sharing. But now we are taught to throw everything within us into public light and common pawing.”

— Ayn Rand, The Fountainhead

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This is how the growth of the current world population occurs in real time. (as of January 2, 2018… and counting)

Así es como se da en tiempo real el crecimiento de la población mundial actual. (al 2 de enero de 2018…y contando) #VanekitaNekita