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Games that emotionally stirs me

1. Final fantasy: Type-0, this is actually a masterpiece, with a really dark theme, and the bloody part is uncensored. The depiction of war is quite realistic. The theme is of God and Human, destiny and hard work, the ending is just...., please don’t hate Machina, if you read the novel you will know why he does that

2. Danganronpa series, the classic hope vs despair, what I like is how optimistic it is while depressing at the same time. I really like Yasuke Matsuda from the Zero novel, don’t know why. Also the V3 Ending is contrary to public opinion is quite good, not choosing anything is also an option, choosing both or more is also an option. Who determine we need to choose one and abandon the others?

3. FF Tactics: War of the Lion, this is the story with a lot of twist, and Delita is a good grey antagonist. You can’t help to understand and relate with his way of thinking, even tough it is morally wrong 

to be continued

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Thought on final fantasy tactics: war of the lion

I honestly never really finished the game myself, just saw it and felt it has a good plot, but the lag on pc emulator just turn me off. That was like 3 years ago I think, when I am still in high school. But recently watch https://www.youtube.com/watch?v=GiJXxc9ySPI, the recap of the story, I remembered why I love Japan so much, it is the plot, Japan has always surprised me with their way of characterization and their take on things in life. The story is about Delita and Ramza, who both has their own take on life. At the end Delita said, “What do you gain from it?”, I understand that, Ramza just like how a protagonist should act, become selflessly heroic even if he is brandished as a heretic from the seemingly comfortable position of a duke’s son, definitely not a fitting end of hero, and Delita, through lie and deceit finally ascend to the throne from being a commoner. I just felt both deserve their ending. The way Delita ask for Ramza is what makes it emotional I think. Delita and Ramza grow together, and they care about each other, Delita’s lust for revenge, his manipulation, I think Ramza know of it yet didn’t mind it much. In a sense, Delita’s lost the only person who understand him the most. I think this is why I felt a bit empty watching the ending. It is sad, but there is no other way.

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People look down on stuff like geography and meteorology, and not only because they’re standing on one and being soaked by the other. They don’t look quite like real science. But geography is only physics slowed down and with a few trees stuck on it, and meteorology is full of excitingly fashionable chaos and complexity. And summer isn’t a time. It’s a place as well. Summer is a moving creature and likes to go south for the winter.

Terry Pratchett - Feet Of Clay (via terrypratchettparadise)

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A circumhorizontal arc, often called a fire rainbow, is an optical phenomenon in which an ice halo forms by hexagonal, plate-shaped ice crystals in high level cirrus clouds. The halo is so large that the arc appears parallel to the horizon, hence the name. When the sun is very high in the sky, sunlight entering flat, hexagon shaped ice crystals gets split into individual colors just like in a prism.

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Anyone can tell me how to solve this ???

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Know the Mechanisms by which Microorganisms exhibit Resistance to Antimicrobials! [High Yield Topic]

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The Central Dogma

What is it? The central dogma is a common way to refer to one of the most fundamental concepts in biology: how organisms store, transmit, and act upon information. It was coined by Francis Crick partially because he forgot the meaning of the word ‘dogma.’ (Really, he did).  Basically it goes like this:

Image Credit: Khan Academy, “Intro to gene expression”

Long term storage of information (like how to build a protein, or how often a cell should divide) is stored in DNA. When the cell needs that information, the DNA is transcribed into messenger RNA, or mRNA. Then, that mRNA is translated into a chain of amino acids, which folds into a protein that can do work within the cell. It could perform a chemical reaction, become part of a cellular structure, regulate transcription of specific genes, etc.

The DNA to RNA transition is called transcription because the mRNA is basically a copy of the DNA but with a slightly different molecule. It’s pretty easy to look at an RNA sequence and figure out what portion of the DNA it was transcribed from. The RNA to protein transition is called translation because it’s like the RNA is being translated into a completely different language. Every three bases of RNA (a codon) codes for a specific amino acid. But, since there are 64 possible combinations of RNA bases and only 20 amino acids, there is a lot of redundancy. If you know the exact sequence of amino acids in a protein, you can’t figure out the exact RNA sequence that created it.

What are the exceptions to it? Although broad, simple theories are appealing, they almost never capture the true complexity of life. The central dogma is true for most processes in the cell. Genes make RNA, which makes protein. However, there are some exceptions.

Viruses lack the ability to replicate or reproduce by themselves, so they have to infect other cells to survive. Some viruses don’t have a genome made of DNA, they have an RNA genome instead. One class of these is called retroviruses, because they move backwards against the usual flow of information described by the central dogma. When they invade the cell, they reverse transcribe their RNA genome into DNA, which gets inserted into the genome of the host. HIV (human immunodeficiency virus) is an example of a retrovirus.

Prions are another example of a process that defies the central dogma. They are proteins that can cause disease by triggering other proteins to switch into a misfolded state. They are infectious, but they don’t have any RNA or DNA genomes, they’re just a single protein. The first prion discovered was called Prion Protein, because scientists are very creative. Many animals have genes for prion proteins and have tons of normal, healthy prion protein in their bodies. However, these proteins can change shape (misfold) into an alternate, infectious state. Once one protein misfolds, it gets all the other prion protein around it to misfold as well. They clump up into giant, stable aggregates of proteins, which end up killing the cell they’re in. Then, the prions find other cells to infect and kill. So, they act like pathogens, but they don’t have any genome and don’t even fit the definition of a living thing. Examples of prion diseases include mad cow disease, Creutzfeldt-Jakob disease, kuru, and possibly Alzheimer’s (the research on this is still pretty new). There are no current treatments for prion diseases, but fortunately they are pretty rare.