coolcreativehippo

[coolcreativehippo]

I know you're probably feeling angry right now. Channel your rage with this playlist to either burn off steam or prepare for battle. Or both.

What's your favorite song on this playlist and why?

[coolcreativehippo]

Tumblr Tuesday: Moo Deng, Queen of Our Hearts

Moo Deng, bouncy pork, literal baby girl. The knee chomp, the bath aversion, the belly rolls, the cheek scritches, the sleepy snot bubble, the exasperated scream—she has it all. Moo Deng, we love you.

@polarmary:

@najmetender:

@thwipped:

@marissasketch:

@rabbit1225:

@batwynn:

@seasneeze:

@artbyjasonleung:

@clurzo:

@projectniko:

@vilicoco:

@anxiette:

@celesse:

@fluffysheeps:

@tofupixel:

@pancake-fluffz:

@alexplantewpg:

@beepophobia:

@jeeklaart:

@eiririnn:

@kollapsar:

@twinkskeletons:

@oddarette:

@kentrl-z:

[coolcreativehippo]

obsessed with this baby hippo from thailand's khao khew zoo.. she has been so utterly betrayed by the world

[coolcreativehippo]

This song is an absolute banger. I want more people to know it exists, in case it makes your brain as happy as mine.

[coolcreativehippo]

When you see a corporation not pay $16 BILLION in taxes, remember those corporations are funding Republican politicians who want you to be upset with immigrants and migrants.

[coolcreativehippo]

I love this band

[coolcreativehippo]

this post hasn't left my mind since i've first saw it

[coolcreativehippo]

"A first-of-its-kind report has discovered that altering the ingredients list or manufacturing methods of widely used medication can really cut back on carbon emissions.

They found a reduction of 26 million tons, enough to cancel out the whole carbon footprint of the city of Geneva for a decade. Best of all, it’s already happening, and in fact, is almost done—those emissions were already saved.

The lifesaving HIV treatment dolutegravir (DTG) is used by 24 million people worldwide.

Today, over 110 low and middle-income countries have adopted DTG as the preferred treatment option. Rapid voluntary licensing of the medicine, including its pediatric version, to over a dozen generic manufacturers, significantly drove down prices, and it’s estimated that 1.1 million lives will be saved from HIV/AIDS-related deaths by 2027.

Its predecessor, efavirenz, contained 1200 milligrams of active ingredient across the three active compounds present, while DTG contains 650 milligrams of just one compound. This small difference—literally measurable in single digits of paper clips by weight—was enough to change the carbon emissions footprint of the medication by a factor of 2.6.

The incredible discovery was made in a recent report by Unitaid, a global public-private partnership that invests in new health products and solutions for low and middle-income countries, called Milligrams to Megatons, and is the first published research to compare carbon footprints between commonly used medications.

“This magnitude of carbon footprint reduction surpasses many hard-won achievements of climate mitigation in health and other sectors,” the authors of the report write.

At the rate at which DTG is produced, since it entered into production and treatment regime in 2017, 2.6 million fewer tons of CO2 have entered the atmosphere every year than if efavirenz was still the standard treatment option.

Health Policy Watch reports that the global medical sector’s carbon emissions stand at roughly 5% of the global carbon emissions and are larger than the emissions of many big countries, and 2.5 times as much as aviation.

“This report demonstrates that we can achieve significant health improvements while also making strides in reducing carbon emissions. By adopting innovative practices and prioritizing sustainability, we can ensure that medicines like DTG are not only effective but also environmentally responsible,” Vincent Bretin, Director of Unitaid’s Results and Climate Team told Health Policy Watch."

-via Good News Network, July 17, 2024

[coolcreativehippo]

Help keep COVID-19 vaccines free in the United States!

The People's CDC has created a template for sending a letter to Congress about extending the Bridge Access Program, which has been providing free COVID vaccines to uninsured people in the United States. As of time time of this posting (July 19, 2024), the Bridge Access Program will be ending next month.

My family needs the Bridge Access Program! It is the ONLY way for poor households like mine to access COVID vaccines. If this program goes away, a lot of people like my family are going to have even less access to the outside world.

My family has already had difficulty utilizing the Bridge Access Program for our updated boosters, because many vaccination locations are preemptively (and suspiciously) claiming they can't offer the vaccines for free. We tried three different locations for our most recent booster, and we still haven't been able to get it, even though the Bridge Access Program is supposed to still be in effect. We keep getting told there are "none available" by pharmacies like CVS and Walgreens, and the current wait for an appointment at the sliding-scale clinic is longer than the remainder of the Bridge Access Program. By the time I get in, it won't be free anymore, unless Congress is convinced to extend the program.

Vaccine access cannot be allowed to be taken from us like this. Lack of updated vaccines is why I can barely leave the house.

COVID hasn't gone away, vaccine boosters are vital, and I'm asking US residents to fill out and submit the form. It's a small way to help, but the People's CDC has had success with these campaigns in the past. I choose to cling to what slivers of hope I can right now.

[coolcreativehippo]

"A large clinical trial in South Africa and Uganda has shown that a twice-yearly injection of a new pre-exposure prophylaxis drug gives young women total protection from HIV infection.

The trial tested whether the six-month injection of lenacapavir would provide better protection against HIV infection than two other drugs, both daily pills. All three medications are pre-exposure prophylaxis (or PrEP) drugs.

Physician-scientist Linda-Gail Bekker, principal investigator for the South African part of the study, tells Nadine Dreyer what makes this breakthough so significant and what to expect next.

Tell us about the trial and what it set out to achieve

The Purpose 1 trial with 5,000 participants took place at three sites in Uganda and 25 sites in South Africa to test the efficacy of lenacapavir and two other drugs.

Lenacapavir (Len LA) is a fusion capside inhibitor. It interferes with the HIV capsid, a protein shell that protects HIV’s genetic material and enzymes needed for replication. It is administered just under the skin, once every six months.

The randomised controlled trial, sponsored by the drug developers Gilead Sciences, tested several things.

The first was whether a six-monthly injection of lenacapavir was safe and would provide better protection against HIV infection as PrEP for women between the ages of 16 and 25 years than Truvada F/TDF, a daily PrEP pill in wide use that has been available for more than a decade.

Secondly, the trial also tested whether Descovy F/TAF, a newer daily pill, was as effective as F/TDF...

The trial had three arms. Young women were randomly assigned to one of the arms in a 2:2:1 ratio (Len LA: F/TAF oral: F/TDF oral) in a double blinded fashion. This means neither the participants nor the researchers knew which treatment participants were receiving until the clinical trial was over.

In eastern and southern Africa, young women are the population who bear the brunt of new HIV infections. They also find a daily PrEP regimen challenging to maintain, for a number of social and structural reasons.

During the randomised phase of the trial none of the 2,134 women who received lenacapavir contracted HIV. There was 100 percent efficiency.

By comparison, 16 of the 1,068 women (or 1.5%) who took Truvada (F/TDF) and 39 of 2,136 (1.8%) who received Descovy (F/TAF) contracted the HIV virus...

What is the significance of these trials?

This breakthrough gives great hope that we have a proven, highly effective prevention tool to protect people from HIV.

There were 1.3 million new HIV infections globally in the past year. Although that’s fewer than the 2 million infections seen in 2010, it is clear that at this rate we are not going to meet the HIV new infection target that UNAIDS set for 2025 (fewer than 500,000 globally) or potentially even the goal to end Aids by 2030...

For young people, the daily decision to take a pill or use a condom or take a pill at the time of sexual intercourse can be very challenging.

HIV scientists and activists hope that young people may find that having to make this “prevention decision” only twice a year may reduce unpredictability and barriers.

For a young woman who struggles to get to an appointment at a clinic in a town or who can’t keep pills without facing stigma or violence, an injection just twice a year is the option that could keep her free of HIV.

What happens now?

The plan is that the Purpose 1 trial will go on but now in an “open label” phase. This means that study participants will be “unblinded”: they will be told whether they have been in the “injectable” or oral TDF or oral TAF groups.

They will be offered the choice of PrEP they would prefer as the trial continues.

A sister trial is also under way: Purpose 2 is being conducted in a number of regions including some sites in Africa among cisgender men, and transgender and nonbinary people who have sex with men.

It’s important to conduct trials among different groups because we have seen differences in effectiveness. Whether the sex is anal or vaginal is important and may have an impact on effectiveness.

How long until the drug is rolled out?

We have read in a Gilead Sciences press statement that within the next couple of months [from July 2024] the company will submit the dossier with all the results to a number of country regulators, particularly the Ugandan and South African regulators.

The World Health Organization will also review the data and may issue recommendations.

We hope then that this new drug will be adopted into WHO and country guidelines.

We also hope we may begin to see the drug being tested in more studies to understand better how to incorporate it into real world settings.

Price is a critical factor to ensure access and distribution in the public sector where it is badly needed.

Gilead Sciences has said it will offer licences to companies that make generic drugs, which is another critical way to get prices down.

In an ideal world, governments will be able to purchase this affordably and it will be offered to all who want it and need protection against HIV."

-via The Conversation, July 3, 2024

[coolcreativehippo]

This was published weeks ago, yet I haven't seen a single mainstream news source covering this massive scandal. Read the full article here: https://www.erininthemorning.com/p/trans-youth-suicides-covered-up-by

[coolcreativehippo]

[image description: a tweet by user @indigenousAI saying

“fun fact: as a DV survivor i cannot register to vote because doing so makes my address public. anyone who is fleeing or hiding from an abuser is automatically disenfranchised from the political process and this is a feature, not a bug”]

[coolcreativehippo]

psychiatrists: You can’t stop this medication cold turkey. You need to stay on your meds no matter what. If you don’t stay on your meds I won’t treat you as my patient anymore

psychiatrists when you need your meds refilled: yeah I can do that in about 10 business days. oh you need it right now? or you’re going to end up hospitalized? meh I don’t care. good luck idiot

[coolcreativehippo]

There are so many unintended consequences to well-intentioned actions. It feels like a game you can’t win.

[coolcreativehippo]

Cartoon by https://www.instagram.com/vulgadrawings

AGGRIEVED ENTITLEMENT

looks like this:

[The single panel comic has a pink background. A white man with short brown hair wearing a white collared shirt and black pants is sitting on one end of a wide wooden bench. His arms are crossed and he is staring straight ahead, his legs splayed out to either side wider than his hips. To his right stands a woman with dark hair and brown skin wearing a green vest over a lilac long-sleeved shirt and black shirt. She is gesturing with one hand at the bench, smiling as she looks sideways at it.]

Woman: I THINK I DESERVE TO SIT ON THIS BENCH TOO!

[Below the first drawing, the woman is now sitting on the opposite end of the bench, her hands on her closed knees. She is looking sideways apprehensively at the man who has fallen onto the ground. His arms are flung out and he looks horrified.]

White man: OH MY GOD I'VE BEEN PUSHED OFF! THERE'S NO ROOM FOR ME ON [Underlined text.] MY [End underlined text.] BENCH ANYMORE!

See also: human conversation.

"Men perceived the discussion as being equal when women talked only 15% of the time, and the discussion as being dominated by women if they talked only 30% of the time."

[coolcreativehippo]

SAG-AFTRA IS STRIKING AGAIN

This time, for video games.

Some key information:

They are striking so all performers will have protection against AI

The struck companies are those signed to the Interactive Media Agreement

The listed companies by SAG-AFTRA include Activision Productions Inc, Blindlight LLC, Disney Character Voices Inc, Electronic Arts Productions Inc, Formosa Interactive LLC, Insomniac Games Inc, Llama Productions LLC, Take 2 Productions Inc, VoiceWorks Productions Inc and WB Games Inc. Though this may not be everyone.

Important things from the FAQ:

Some games from struck companies are non-struck (due to the Collective Bargaining Agreement still being in effect)

Localisations will be affected if covered under the Interactive Localization Agreement

Actors who are part of SAG-AFTRA cannot work for non-union or independent/low-budged productions during the strike unless they are signed to an Interim Interactive Media Agreement, Interim Interactive Localization Agreement or a Tiered-Budget Independent Interactive Media Agreement

Similarly to the previous strike, struck work cannot be promoted. This includes accepting awards for performances in struck games. This does NOT include hosting/performing a skit at an awards show and San Diego Comic Con (the latter due to the close proximity to the calling of the strike)

As implied by the point above, SAG-AFTRA performers cannot partake in panels related to struck games or companies, including finished games produced by struck companies

The best way to check if a game is struck is to use the search tool provided by SAG-AFTRA

Most importantly: You are NOT being asked to stop playing video games, as highlighted in the FAQ for creators and streamers. This does NOT cross the picket line. Though please do talk about the strike and show your solidarity

I expect to see the same amount of support from y'all that we saw in the last strike. Just because it's video games doesn't mean performers deserve any less support and protection.

Also please reblog with any additions (with sources - we are NOT here to spread misinformation)! And please correct me if anything listed here is incorrect.

SOURCES:

Video Game Strike FAQs | SAG-AFTRA (sagaftra.org)

SAG-AFTRA Members Who Work on Video Games Go on Strike | SAG-AFTRA (sagaftra.org)

[coolcreativehippo]

yknow it took a meme for me to realize every member of greenday is bisexual however, i also didnt really look at pictures of the band greenday before that and like

how was this ever a question? like no shade but this group is like if danny elfman, american flavored gerard way and the “i will find you and i will kill you” guy got blasted with an emo fruitification beam and formed a band