Essential medicines are medicines that meet the population's priority needs for health care services. It is chosen by taking into account the prevalence, safety, efficacy, and relative cost-effectiveness of the disease.
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Hibidil solution for local application Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Dermatology
active ingredients: Chlorhexidine
what is Hibidil medication used for and indication?
Local adjunctive treatment of primarily bacterial skin conditions or likely to become superinfected.
NB: antiseptic agents are not sterilizing: they temporarily reduce the number of microorganisms.
Presentation (s) available for Hibidil
5 presentations are available for this drug:
1 polyethylene single-dose container (s) of 15 ml
5 single-dose container (s) of 15 ml
10 single-dose container (s) of 15 ml
25 single-dose container (s) of 15 ml
240 polyethylene single-dose container (s) of 15 ml
FEATURE DESCRIPTION Pharmaceutical class antiseptics and disinfectants Active substance (s) per 100 ml: chlorhexidine (digluconate) (50 mg) General medicine no Pharmaceutical form solution for sterile application Route (s) of administration cutaneous Selling price unregulated price Social security reimbursement rate 0% Laboratory (s) Laboratory (s) manufacturer Hibidil Conditions of issue available without prescription
Hibidil Dosage
Ready-to-use, single-use solution.
DO NOT SWALLOW. EXTERNAL USE. DERMAL.
This product can be applied directly to wounds.
Do not rinse.
Hibidil Contraindications
Never use HIBIDIL, solution for local application, sterile in the following cases:
Hypersensitivity to one of the components (or group sensitization),
In contact with the brain, the meninges, the eye, the mucous membranes, nor penetrate the ear canal in the event of eardrum perforation.
This product must not be used for the disinfection of medico-surgical equipment.
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST
How To Take Hibidil ?
Method and route of administration
Dermal.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist for more information.
how does Hibidil work?
Pharmacotherapeutic group: antiseptics and disinfectants, ATC code: D08AC02.
How To Store Hibidil ?
Keep this medication out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date refers to the last day of that month.
This medication should be stored at a temperature below 30 ° C.
Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
Hibidil Side Effects
Like all medicines, HIBIDIL, solution for topical application, sterile can cause side effects, although not everybody gets them. such as :
allergic eczema on contact with the product,
rarely, general allergic accident up to anaphylactic shock.
Due to the presence of 90 percent ethanol (alcohol), frequent applications to the skin can cause irritation and dryness of the skin.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Hibidil Interactions
This medication should not be used at the same time as other local antiseptics (risk of incompatibility or ineffectiveness). Prior use of soap should be followed by thorough rinsing.
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.
Effects on ability to Drive and use machines
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Warnings and Precautions
Warnings
Although the transcutaneous absorption of chlorhexidine is very low, the risk of systemic effects cannot be excluded. They are all the more to be feared as the antiseptic is used over a large area, on damaged skin (in particular burnt) a mucous membrane, premature or infant skin (due to the surface / weight ratio and the diaper occlusion effect at the seat).
As soon as the packaging of an antiseptic preparation is opened, microbial contamination is possible.
The use of chlorhexidine solutions, alcoholic or aqueous, for antisepsis of the skin, before invasive surgery has been associated with chemical burns in newborns. Based on reported cases and published literature, this risk appears to be higher in premature infants, especially those born before 32 weeks of gestation and in the first 2 weeks of life.
Remove all soaked materials, gowns or drape before proceeding. Do not use excessive amounts and do not leave the solution in folds of the skin or on the patient or on sheets or other material in direct contact with the patient. When occlusive dressings are used on areas previously exposed to HIBIDIL, every precaution should be taken to ensure that there is no excess product prior to application of the dressing.
Precautions for use
As soon as the packaging of an antiseptic preparation is opened, microbial contamination is possible.
Do not use chlorine-based products (bleach, etc.) to clean fabrics or containers that have been in contact with HIBIDIL: risk of indelible stains.
PREGNANCY & BREAST-FEEDING & FERTILITY
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if I overdose from Hibidil ?
In the event of massive oral ingestion, seek the advice of a poison control center.
What should I do if I miss a dose?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if you stop taking Hibidil ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What is Forms and Composition ?
Appearance and shape
Solution for local application.
15 ml in single-dose container (polyethylene).
Other shapes
HIBIDIL, solution for local application, sterile, box of 240 single-dose containers of 15 ml
HIBIDIL, solution for local application, sterile, box of 1 single-dose container of 15 ml
Composition
Active ingredient Sterile solution for local application Chlorhexidine digluconate 0.5 mg *
* per unit dose
Active ingredients: Chlorhexidine digluconate
Excipients with known effects ?
Azorubine
Other excipients: Nonoxinol 9, Ethanol, Gluconolactone (for pH adjustment), Sodium hydroxide (for pH adjustment), Purified water
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3lvXLDg via Edrug Online
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Paroex 0.12% Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Stomatology active ingredients: Chlorhexidine
what is Paroex ?
This medication is usually prescribed for:
Oral infection
Postoperative care in stomatology
what is Paroex medication used for and indication?
It is indicated for the local adjunctive treatment of infections of the mouth, or in care after surgery of the oral cavity.
Presentation (s) available for Paroex 0.12%
5 presentations are available for this drug:
1 polyterephthalate (PET) bottle (s) with 5000 ml dosing pump
1 polyterephthalate (PET) bottle (s) of 50 ml
1 polyterephthalate (PET) bottle (s) of 100 ml
1 polyterephthalate (PET) bottle (s) of 300 ml with polypropylene measuring cup
1 polyterephthalate (PET) bottle (s) of 500 ml
FEATURE DESCRIPTION Pharmaceutical class stomatological preparations Active substance (s) per 100 ml of mouthwash solution: chlorhexidine digluconate solution (0.6360 g) General medicine no Pharmaceutical form mouthwash solution Route (s) of administration oral route other Social security reimbursement rate 15% Laboratory (s) CENTER SPECIALTIES PHARMACEUTI Conditions of issue restricted prescription drug
Paroex Dosage
RESERVED FOR ADULTS AND CHILDREN OVER 6 YEARS OLD
For each mouthwash, use the contents of half a scoop (12 ml); if this presentation does not contain a cup, use a tablespoon, i.e. approximately 15 ml.
Rinse your mouth thoroughly for about a minute with the pure solution.
How often and when the drug should be administered
The number of mouthwashes is 1 to 3 per day.
Paroex Contraindications
Never use PAROEX 0.12 PERCENT, mouthwash solution in the following cases:
allergy to chlorhexidine or to any part of the solution.
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST
How To Take Paroex ?
Method and route of administration
Use locally in mouthwashes.
DO NOT SWALLOW.
This solution should be used pure, undiluted.
Mouthwashes should be done AFTER brushing and rinsing.
Duration of treatment
Do not continue treatment for more than 5 days without medical advice.
how does Paroex work?
Pharmacotherapeutic group: STOMATOLOGY / LOCAL ANTISEPTIC TREATMENT
(A: digestive system and metabolism)
How To Store Paroex ?
Keep out of the reach and sight of children.
Expiration date
Do not use PAROEX 0.12 PERCENT, solution for mouthwash after the expiry date stated on the outer packaging.
Storage conditions
After opening the bottle, this medication can be stored for a maximum of 30 days (90 days for the 5000 ml format with pump).
If necessary, warnings against certain visible signs of deterioration
Medicines should not be thrown away with wastewater or household waste. Ask your pharmacist what to do with any unused medicine. These measures will help protect the environment.
Paroex Side Effects
Like all medicines, PAROEX 0.12 PERCENT, mouthwash solution can cause side effects, although not everybody gets them.
Brown discoloration of the tongue and teeth, particularly in tea and coffee users, disappearing when treatment is stopped.
Possibility of allergic reactions: irritations, skin reactions, swelling of the salivary glands, swelling of the neck or face. If you experience any of these symptoms, stop treatment and see a doctor.
Possibility of taste alteration or burning sensation of the tongue at the start of treatment.
Occasionally, peeling of the oral mucosa.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Paroex Interactions
Use of other drugs
Do not use several medicines containing an antiseptic at the same time or in close proximity.
IN ORDER TO AVOID POSSIBLE INTERACTIONS BETWEEN SEVERAL MEDICINES, ANY OTHER TREATMENT IN PROGRESS MUST BE SENIORIZED TO YOUR DOCTOR OR YOUR PHARMACIST.
Effects on ability to Drive and use machines
Effects on the ability to drive and use machines are not expected.
Warnings and Precautions
Take special care with PAROEX 0.12 PERCENT, mouthwash solution:
DO NOT LEAVE THIS MEDICINE WITHIN THE REACH OF CHILDREN.
Prolonged use of this medication is undesirable because it can alter the natural microbial balance in the mouth and throat.
If signs of infection worsen or if there is no improvement after 5 days:
CONSULT YOUR DENTAL SURGEON OR STOMATOLOGIST
Precautions for use
Do not put the product in contact with the eyes.
Do not introduce the product into the nose or ears.
KEEP OUT OF REACH OF CHILDREN.
DO NOT SWALLOW.
IF IN DOUBT, DO NOT HESITATE TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy and breast feeding
This drug should be used with caution during pregnancy and lactation.
In general, you should seek advice from your doctor or pharmacist before taking any medication.
Sportsmen
Not applicable.
What happens if I overdose from Paroex ?
After oral ingestion of chlorhexidine, the following effects have been reported: atrophic gastritis, esophageal and hepatic lesions in case of very high doses.
In addition, this proprietary product contains terpene derivatives, as excipients, which can lower the epileptogenic threshold and cause, at excessive doses, neurological accidents in children (such as convulsions) and in elderly subjects (such as agitation and confusion). Respect the recommended dosages and duration of treatment (see section Posology and method of administration).
What should I do if I miss a dose?
Instructions for missing one or more doses
Not applicable.
What happens if you stop taking Paroex ?
Risk of withdrawal syndrome
Not applicable.
What is Forms and Composition ?
Appearance and shape
Lack of information in the MA.
500 ml in bottle (Polyethylene terephthalate) with VISTOP stopper (Polypropylene) and cap (PE)) with measuring cup (Polypropylene)
Other shapes
PAROEX 0.12 PERCENT, solution for mouthwash, 100 ml vial
PAROEX 0.12 PERCENT, mouthwash solution, 5000 ml vial
PAROEX 0.12 PERCENT, solution for mouthwash, 50 ml vial
PAROEX 0.12 PERCENT, solution for mouthwash, 300 ml bottle
COMPOSITION
p bottle from 100 ml 300 ml 500 ml Chlorhexidine (DCI) digluconate 120 mg 360 mg 600 mg (as a 20% solution (w / v): 0.636 g / 100 ml)
Excipients: glycerol, acesulfame potassium, polyoxyethylenated castor oil, propylene glycol, azorubine, Optamint 757515 flavor (menthol, anethol, eucalyptol, essential oil of mint, menthone, menthyl acetate, racemic menthol, propylene glycol, triacetin, essential oil of star anise , essential oil of geranium, vanillin, maltol, essential oil of mandarin, ethanol), purified water.
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/36D1OqY via Edrug Online
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Posine, eye drops Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Ophthalmology Active ingredients: Chlorhexidine , Synephrine
Medicinal product withdrawn from the market on 07/03/2006
what is Posine ?
This medication is usually prescribed for:
Non-infectious conjunctival irritation
what is Posine medication used for and indication?
Adjunctive treatment of non-infectious conjunctival irritations.
Posine Dosage
Local route.
RESERVED FOR ADULTS AND CHILDREN OVER 12 YEARS OLD. IN EYE INSTILLATION.
One drop of eye drops 2 to 4 times a day.
Instill 1 drop of eye drops in the lower conjunctival cul-de-sac of the diseased eye (s) by looking upwards and pulling the lower eyelid slightly downwards.
Do not touch the eye or the eyelids with the tip of the bottle. Recap the bottle after use.
Posine Contraindications
CONTRA-INDICATED
This medication is contraindicated in the event of:
hypersensitivity to one of the constituents of the eye drops,
risk of glaucoma by closing the angle.
ADVISED AGAINST:
This medication is generally not recommended in the following situations:
during the first trimester of pregnancy and in case of breastfeeding:
pregnancy: there are no reliable data on teratogenesis in animals.
There is currently no relevant, or sufficient number, to assess a possible malformative effect of synephrine when administered during pregnancy.
Consequently, the use of drugs containing synephrine is not recommended during the first trimester.
Breast-feeding: due to the lack of data on the passage of this drug in breast milk, the use of this one should be avoided during breast-
Posine Side Effects
feeding.
in combination with bromocriptine; guanethidine and related; non-selective MAOIs (iproniazid, nialamide) (see interactions).
how does Posine work?
Risk of acute glaucoma by closing the angle.
Possibility of transient irritation.
Possibility of allergic reactions: blepharitis, conjunctivitis.
Repeated instillations can cause an annoying mydriasis, superficial punctate keratitis; exceptionally, by systemic effect of synephrine, an increase in blood pressure, tremors, pallor, headaches, cardiac arrhythmias.
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3eXNbm7 via Edrug Online
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prexidine solution for mouthwashUses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Stomatology active ingredients: Chlorhexidine
what is prexidine ?
This medication is usually prescribed for:
Oral infection
Postoperative care in stomatology
what is prexidine medication used for and indication?
This medication is a mouthwash.
It is indicated for the local adjunctive treatment of infections of the mouth, or in care after surgical intervention of the oral cavity.
Presentation (s) available for Prexidine 0.12%
3 presentations are available for this drug:
1 polyterephthalate (PET) bottle (s) of 55 ml
1 polyterephthalate (PET) bottle (s) of 200 ml with measuring cup (s)
1 polyterephthalate (PET) bottle (s) of 500 ml
FEATURE DESCRIPTION Pharmaceutical class stomatological preparations Active substance (s) chlorhexidine digluconate solution General medicine no Pharmaceutical form mouthwash solution Route (s) of administration oral route other Social security reimbursement rate 15% Laboratory (s) EXPANSCIENCE Conditions of issue restricted prescription drug
prexidine Dosage
RESERVED FOR ADULTS AND CHILDREN OVER 6 YEARS OLD.
200 ml bottle: For each mouthwash, use the measuring cup, filling it up to the mark (15 ml). If there is no cup, use the contents of one tablespoon of solution (15 ml).
55 ml and 500 ml bottles: Use the content of one tablespoon of solution (i.e. 15 ml).
Rinse mouth thoroughly for about a minute with the pure solution.
How often and when the drug should be administered
The number of mouthwashes is 1 to 3 per day.
prexidine Contraindications
Never use PREXIDINE 0.12 PERCENT, mouthwash solution in the following cases:
allergy to chlorhexidine.
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK THE OPINION OF YOUR DENTIST OR OSTOMATOLOGIST AND / OR YOUR DOCTOR OR PHARMACIST
How To Take prexidine ?
Method and route of administration
Use locally as a mouthwash.
DO NOT SWALLOW.
This solution should be used pure, undiluted.
Mouthwashes should be done AFTER brushing and rinsing.
Duration of treatment
Do not continue treatment for more than 5 days without medical advice.
how does prexidine work?
Action mechanism
Pharmacotherapeutic group: STOMATOLOGY / LOCAL ANTISEPTIC TREATMENT, ATC code: A01AB03.
How To Store prexidine ?
Keep this medication out of the sight and reach of children.
Do not use PREXIDINE 0.12 PERCENT, solution for mouthwash after the expiry date stated on the outer packaging. The expiration date refers to the last day of the month.
Store at a temperature not exceeding + 25 ° C.
Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
prexidine Side Effects
Like all medicines, PREXIDINE 0.12 PERCENT, mouthwash solution can cause side effects, although not everybody gets them.
Brown discoloration of the tongue and teeth, especially in tea or coffee drinkers, disappearing when treatment is stopped.
Possibility of allergic reactions: irritations, skin reactions, swelling of the salivary glands. If you experience any of these symptoms, stop treatment and see a doctor.
Possibility of taste alteration or burning sensation of the tongue at the start of treatment.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
prexidine Interactions
Taking or using other medicines:
Do not use several medicines containing an antiseptic at the same time or in close proximity.
IN ORDER TO AVOID POSSIBLE INTERACTIONS BETWEEN SEVERAL MEDICINES, ANY OTHER TREATMENT IN PROGRESS MUST BE SIGNIFICANTLY TO YOUR DENTAL SURGEON, YOUR STOMATOLOGIST OR YOUR PHARMACIST.
Effects on ability to Drive and use machines
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Warnings and Precautions
Warnings
The indication does not justify prolonged treatment, especially since it could expose to an imbalance of the normal microbial flora of the oral cavity, with a risk of bacterial or fungal diffusion (candidiasis).
In the event of persistence of symptoms beyond 5 days and / or associated fever, the action to be taken should be reassessed and systemic antibiotic therapy should be considered.
Interrupt the treatment in case of swelling of the parotids.
Precautions for use
Do not put the product in contact with the eyes or nose.
Do not introduce the product into the ear canal.
Due to the presence of alcohol:
Keep out of the reach of children.
Do not swallow.
PREGNANCY & BREAST-FEEDING & FERTILITY
This drug should be used with caution during pregnancy and lactation.
In general, you should seek advice from your doctor or pharmacist before taking any medication.
What happens if I overdose from prexidine ?
An overdose is not expected under normal conditions of use of this mouthwash solution.
In the event of accidental oral ingestion of chlorhexidine, the following effects have been reported: atrophic gastritis, esophageal and hepatic lesions in case of very high doses.
In the event of accidental ingestion in children, take into account the presence of alcohol (0.1 g / ml).
In addition, this specialty contains terpene derivatives, as excipients, which can lower the epileptogenic threshold and cause, in excessive doses, in the event of accidental oral ingestion, neurological accidents in children (such as convulsions). and in the elderly (agitation and confusion type). Follow the recommended mode and route of administration, dosages and duration of treatment (see section Posology and method of administration).
An accidental projection by the ocular route of a solution of chlorhexidine is likely to cause corneal lesions requiring specialized care.
What should I do if I miss a dose?
If you forget to use PREXIDINE 0.12 PERCENT, mouthwash solution
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if you stop taking prexidine ?
If you stop using PREXIDINE 0.12 PERCENT, mouthwash solution
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
If you have further questions on the use of this medicine, ask your doctor or pharmacist for more information.
What is Forms and Composition ?
SHAPES and PRESENTATIONS
Solution for mouthwash.
60 ml PET (polyethylene terephthalate) bottle sealed with an aluminum cap with a polyethylene seal (filled to 55 ml).
Other shapes
PREXIDINE 0.12 PERCENT, solution for mouthwash, bottle (+ measuring cup) of 200 ml
PREXIDINE 0.12 PERCENT, solution for mouthwash, 500 ml bottle
PREXIDINE 0.12 PERCENT, solution for mouthwash, 300 ml bottle
prexidine composition
p 100 ml Chlorhexidine digluconate 20% solution 120 mg
Excipients (common): saccharin, glycerol, polysorbate 80, alcohol, levomenthol, mint flavor (ethanol, menthol, menthyl acetate, mint essential oil), purified water.
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3nlou5R via Edrug Online
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Text
Angispray Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Otorhinolaryngology Active ingredients: Hexetidine , Propionic acid (E280) , Chlorobutanol
Medicinal product withdrawn from the market on 09/11/2014
what is Angispray ?
This medication is usually prescribed for:
Affection limited to the oral mucosa and oropharynx
what is Angispray medication used for and indication?
Local antibacterial and analgesic adjunctive treatment of affections limited to the oral mucosa and the oropharynx.
NB: given the general clinical signs of bacterial infection, general antibiotic therapy should be considered.
Angispray Dosage
Adult and child over 15 years :
1 spray 4 to 6 times a day.
Avoid breathing in while spraying.
Angispray Contraindications
CONTRA-INDICATED:
Known allergy to local anesthetics and hexetidine.
Do not use in children under 15 years old.
ADVISED AGAINST:
This medicine contains 0.22 g of alcohol per spray. It is not recommended in patients suffering from liver disease, alcoholism, epilepsy, as well as in pregnant women.
Pregnancy: in the absence of experimental and clinical data with this combination, ANGISPRAY is not recommended during pregnancy.
Breast-feeding: in the absence of data on the passage of this medication into breast milk, ANGISPRAY should be avoided during breast-feeding.
how does Angispray work?
PREPARATIONS FOR THE THROAT.
ATC code: R02A.
(R: respiratory system).
Preparation for oral or oropharyngeal use combining a local antiseptic (hexetidine) and a local anesthetic (chlorobutanol).
Angispray Side Effects
Anaphylactic reaction
Numbness of the tongue
Wrong way
Irritation of the oral mucosa
Dryness of the oral mucosa
Sensitization to hexetidine and local anesthetics with risks of anaphylactic reaction.
Temporary numbness of the tongue and possibility of aspiration (see warnings).
Due to the presence of alcohol (approximately 0.22 g per spray) frequent applications may cause irritation and dryness of the mucous membranes.
Angispray Interactions
The simultaneous or successive use of other antiseptics should be avoided given the possible interferences (antagonism, inactivation).
Hexetidine is inactivated by alkaline solutions.
Hexetidine is inactivated by alkaline solutions.
Warnings and Precautions
WARNINGS
Possibility of aspiration by anesthesia of the oropharyngeal crossroads:
do not use this medication before meals or before taking a drink.
The indication does not justify a prolonged treatment beyond 5 days, especially since it could expose to an imbalance of the normal microbial flora of the oral cavity with a risk of bacterial or fungal diffusion.
Repeated or prolonged treatment in the mucosa may expose the risks of toxic systemic effects of contact anesthetics (damage to the central nervous system with convulsions, depression of the cardiovascular system).
PRECAUTIONS FOR USE:
In the event of persistence of symptoms beyond 5 days and / or associated fever, the action to be taken must be reassessed.
This medicine contains approximately 0.22 g of alcohol per spray. It is not recommended in patients suffering from liver disease, alcoholism, epilepsy, as well as in pregnant women.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
In the absence of experimental and clinical data with this combination, ANGI SPRAY is not recommended during pregnancy.
Breast-feeding
In the absence of data on the passage of this medication into breast milk, ANGI SPRAY should be avoided during breast-feeding.
What happens if I overdose from Angispray ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What should I do if I miss a dose?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if you stop taking Angispray ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What is Forms and Composition ?
Appearance and shape
Lack of information in the MA.
40 ml pressurized bottle (glass).
Composition
Active ingredient Mouthwash Hexetidine 72.8 mg * Propionic acid 47.2 mg * Chlorobutanol 200 mg *
* per unit dose
Active ingredients: Hexetidine , Propionic acid , Chlorobutanol
Excipients: 95 ° ethyl alcohol , Glycerol , Star anise essential oil , Mint essential oil , Clove essential oil , Cinnamon essential oil , Purified water , Pulsating gas: Nitrogen
No excipient with known effect ?
is not present in the composition of this drug
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/38MRlvI via Edrug Online
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Text
OSTEOCAL D3 500 mg / 400 IU Uses, Dosage, Side Effects, Precautions & Warnings
OSTEOCAL D3 500 mg / 400 IU, lozenge, box of 1 bottle of 60 >> Generic drug of the Therapeutic class: Metabolism and nutrition Active principles: Elemental calcium , Cholecalciferol
Medicinal product withdrawn from the market on 03/30/2015
what is OSTEOCAL D3 ?
This medication is usually prescribed for:
Vitamin-calcium deficiency in the elderly
Osteoporosis
what is OSTEOCAL D3 medication used for and indication?
This medication is indicated:
in the elderly, in the event of calcium and vitamin D deficiencies,
in combination with treatments for osteoporosis, when the intake of calcium and vitamin D is insufficient.
Presentation (s) available for Osteocal d3 500 mg / 400 IU
1 polyethylene bottle (s) of 60 tablet (s)
FEATURE DESCRIPTION Pharmaceutical class mineral supplements Active substance (s) for one tablet: calcium carbonate (1250.00 mg), cholecalciferol concentrate, powder form General medicine no Pharmaceutical form tablet to suck Route (s) of administration oral Social security reimbursement rate 65% Laboratory (s) ALKOPHARM Conditions of issue restricted prescription drug
OSTEOCAL D3 Dosage
The daily dosage is 2 tablets per day or 1 tablet morning and evening to suck.
OSTEOCAL D3 Contraindications
Never take OSTEOCAL D3 500 mg / 400 IU, tablet to suck in the following cases:
history of allergy to vitamin D or to one of the constituents,
prolonged immobilization,
abnormally high amount of calcium in the blood (hypercalcaemia),
exaggerated elimination of calcium through the urine (hypercalciuria),
kidney stones (calcium lithiasis),
phenylketonuria (hereditary disease due to enzyme deficiency), due to the presence of aspartame.
How To Take OSTEOCAL D3 ?
Administration mode
Oral route
Duration of treatment
Comply with your doctor’s prescription.
how does OSTEOCAL D3 work?
VITAMINO D-CALCIUM CONTRIBUTION.
(drug active on the calcium balance. A: digestive system and metabolism).
Vitamin D corrects the insufficient intake of vitamin D.
It increases the intestinal absorption of calcium and its fixation on the osteoid tissue.
Calcium intake corrects dietary calcium deficiency.
The daily calcium requirements are of the order of 1000 to 1500 mg of elemental calcium and 500-1000 IU / day of vitamin D.
Vitamin D and calcium correct secondary senile hyperparathyroidism.
An 18-month, double-blind, placebo-controlled study involving 3270 women aged 84 + – 6 years living in health centers, showed a significant decrease in plasma PTH levels. At 18 months, the results of the intention-to-treat analysis revealed 80 hip fractures in the calcium-vitamin D group and 110 hip fractures in the placebo group (p = 0.004). Under the conditions of this study, the treatment of 1387 women prevented 30 hip fractures. After an extension up to 36 months, the following results were obtained: 137 hip fractures in the calcium-vitamin D group and 178 in the placebo group (p <= 0.02).
How To Store OSTEOCAL D3 ?
Keep out of the reach and sight of children.
Expiration date
Do not use OSTEOCAL D3 500 mg / 400 IU, lozenge after the expiry date stated on the bottle.
Storage conditions
No special storage conditions.
If necessary, warnings against certain visible signs of deterioration
Do not use OSTEOCAL D3 500 mg / 400 IU sucking tablet if you notice visible signs of deterioration.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with any unused medicine. These measures will help to protect the environment.
OSTEOCAL D3 Side Effects
Like all medicines, OSTEOCAL D3 500 mg / 400 IU, lozenge can have side effects, although not everybody gets them:
constipation or diarrhea,
bloating, stomach pain,
nausea,
too great an increase in the level of calcium in the blood or urine, in the event of prolonged treatment,
itching, extensive rash, hives.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
OSTEOCAL D3 Interactions
ASSOCIATIONS WHICH ARE THE SUBJECT OF A PRECAUTION FOR USE
Cyclines:
Decrease in the digestive absorption of cyclins.
Take calcium salts away from cyclins (more than 2 hours, if possible).
Digital:
Risk of rhythm disturbances.
Clinical monitoring and, if necessary, control of ECG and serum calcium.
Bisphosphonates:
Risk of reduced digestive absorption of bisphosphonates.
Take calcium salts away from bisphosphonates (more than 2 hours, if possible).
Estramustine:
Decreased digestive absorption of estramustine.
Take calcium salts away from estramustine (more than 2 hours if possible).
Iron (salts) (oral route):
Decreased digestive absorption of iron salts.
Take iron between meals and in the absence of calcium.
COMBINATIONS TO BE TAKEN INTO ACCOUNT
Thiazide diuretics:
Risk of hypercalcemia by reduction of urinary calcium elimination.
Effects on ability to Drive and use machines
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Warnings and Precautions
of prolonged treatment, it is necessary to have the quantity of calcium excreted in the urine checked regularly (calciuria). Depending on the result, your doctor may need to reduce or even interrupt your treatment.
additional administration of calcium and vitamin D in high doses which must be done under strict medical supervision.
associated treatment with bisphosphonates as well as in case of treatment with an antibiotic of the cyclin family, it is advisable to wait at least two hours between the intakes of these drugs and OSTEOCAL D3, tablet to suck
sarcoidosis or kidney failure.
galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency (rare metabolic diseases), due to the presence of lactose.
fructose intolerance (hereditary metabolic disease), due to the presence of sorbitol.
PREGNANCY & BREAST-FEEDING & FERTILITY
This product can be used during pregnancy and lactation. However, the daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D3.
During pregnancy, cholecalciferol overdose should be avoided:
vitamin D overdose during gestation has had teratogenic effects in animals.
in pregnant women, vitamin D overdoses should be avoided because permanent hypercalcemia can cause physical and mental retardation in children, supravalvular aortic stenosis or retinopathy. However, several children were born without malformation after administration of very high doses of vitamin D3 for hypoparathyroidism in the mother.
vitamin D and its metabolites pass into breast milk.
What happens if I overdose from OSTEOCAL D3 ?
If you take more OSTEOCAL D3 500 mg / 400 IU, tablet to suck than you should:
Tell your doctor or pharmacist immediately.
Taking an excessive dose of this medication may cause the following symptoms: nausea, vomiting, intense thirst, constipation.
In case of prolonged overdose, calcifications may appear in the vessels or tissues.
What should I do if I miss a dose?
If you forget to take OSTEOCAL D3 500 mg / 400 IU, tablet to suck:
Do not take a double dose to make up for the dose you forgot to take.
What happens if you stop taking OSTEOCAL D3 ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What is Forms and Composition ?
Appearance and shape
White round tablet.
60 tablets in a bottle (PE).
What is OSTEOCAL D3 500 mg / 400 IU, tablet to suck and contents of the outer packaging?
This medication is in the form of a tablet to suck. Box of 60.
Composition
Active ingredient Tablet to suck Calcium element 500 mg * Cholecalciferol 400 IU *
* per unit dose
Active ingredients: Elemental calcium , Cholecalciferol
Excipients with known effects ?
Aspartame, Lactose monohydrate, Sorbitol
Other excipients: Xylitol, Povidone K 30, Levomenthol, Talc, Magnesium stearate, Mint flavor: Peppermint essential oil, Gum arabic, Maltodextrin
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3lvO3Az via Edrug Online
0 notes
Text
Caltrate Vitamine D3 Uses, Dosage, Side Effects, Precautions & Warnings
CALTRATE VITAMIN D3 600 mg / 400 IU, film-coated tablet >> Generic drug of the Therapeutic class: Metabolism and nutrition Active ingredients: Calcium carbonate , Cholecalciferol
what is Caltrate Vitamine D3 ?
This medicine contains calcium and vitamin D3, which facilitate the absorption of calcium from the intestine and its attachment to the bones.
what is Caltrate Vitamine D3 medication used for and indication?
He is used :
in the treatment of calcium and vitamin D deficiencies in the elderly,
in combination with treatment for osteoporosis when calcium and vitamin D intake is insufficient.
PRESENTATION (S) AVAILABLE FOR CALTRATE VITAMIN D3 600 MG / 400 IU
4 presentations are available for this drug:
1 polyethylene bottle (s) of 30 tablet (s)
1 polyethylene bottle (s) of 60 tablet (s)
1 polyethylene bottle (s) of 90 tablet (s)
1 polyethylene bottle (s) of 180 tablet (s)
FEATURE DESCRIPTION Pharmaceutical class mineral supplements Active substance (s) for one tablet: calcium carbonate (1498.5 mg), cholecalciferol (400 IU) General medicine no Pharmaceutical form coated tablet Route (s) of administration oral Social security reimbursement rate 65% Laboratory (s) PFIZER FAMILY HEALTH Conditions of issue restricted prescription drug
Caltrate Vitamine D3 Dosage
Always take the dose recommended by your doctor. If you are uncertain, consult your doctor or pharmacist.
Caltrate Vitamine D3 Contraindications
Do not take CALTRATE VITAMIN D3 600 mg / 400 IU, film-coated tablet in the following cases:
If you are allergic to vitamin D or any of the other ingredients of Caltrate Vitamin D3.
if you have an abnormally high amount of calcium in your blood (hypercalcaemia) and / or excessive exaggeration of calcium in the urine (hypercalciuria)
if you have kidney stones (calcium lithiasis)
if you have too much vitamin D (hypervitaminosis D)
How To Take Caltrate Vitamine D3 ?
Caltrate Vitamin D3 is presented as film-coated tablets for oral use.
The usual dose is 2 tablets per day, to be swallowed with a full glass of water.
how does Caltrate Vitamine D3 work?
Pharmacotherapeutic group: mineral supplements, ATC code: A12AX.
Vitamin D3 increases the intestinal absorption of calcium.
The increase in parathyroid hormone (PTH), due to calcium deficiency, is responsible for bone resorption. The administration of calcium and vitamin D3 inhibits this increase.
An 18-month, double-blind, placebo-controlled study carried out in 3270 women living in institutions, aged 84 ± 6 years receiving a vitamin D3 supplement (800 IU / day) and calcium phosphate (corresponding to 1200 mg / day of elemental calcium), showed a significant decrease in PTH secretion. After 18 months, according to an “Intention to treat” (ITT) analysis, 80 hip fractures were observed in the calcium-vitamin D group and 110 hip fractures in the placebo group (p = 0.004) . In a 36-month follow-up study, 137 women with at least one hip fracture were observed in the calcium-vitamin D group (n = 1176) versus 178 women in the placebo group (n = 1127) (p = 0.02).
How To Store Caltrate Vitamine D3 ?
Keep this medication out of the sight and reach of children.
Do not use this medicine after the expiry date, which is stated on the pack and the bottle after the abbreviation “EXP”. The expiration date refers to the last day of the month indicated.
This medication should be stored at a temperature not exceeding 25 ° C. Keep the bottle tightly closed, in a dry place.
Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
Caltrate Vitamine D3 Side Effects
Like all medicines, CALTRATE VITAMIN D3 600 mg / 400 IU, film-coated tablet can cause side effects, although not everybody gets them.
Uncommon side effects (affects 1 to 10 users in 1,000): excessive calcium levels in the blood or urine.
Rare side effects (affects 1 to 10 users in 10,000): constipation, bloating, nausea, abdominal pain, diarrhea, itching, rash and hives.
Other side effects (frequency not known): kidney stones.
If you get any of the side effects gets serious, or if you get any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Caltrate Vitamine D3 Interactions
Thiazide diuretics reduce urinary calcium excretion. Due to the increased risk of hypercalcaemia, monitoring of serum calcium is recommended with simultaneous administration of thiazide diuretics.
Systemic corticosteroids reduce the absorption of calcium. In case of concomitant administration of corticosteroids, it may be necessary to increase the dose of Caltrate Vitamin D3.
Combination therapy with ion exchange resins like cholestyramine or laxatives like paraffin oil may reduce gastrointestinal absorption of vitamin D3.
Calcium carbonate may affect the absorption of tetracyclines when administered simultaneously. It is recommended to postpone the intake of tetracyclines at least 2 hours before or 4 to 6 hours after oral intake of calcium.
Hypercalcemia can increase the toxicity of digitalis when calcium and vitamin D are administered simultaneously. Patients should therefore be monitored regularly (ECG control and calcium levels).
In case of concomitant administration of a bisphosphonate or sodium fluoride, it is recommended to postpone the intake of Caltrate Vitamin D3 by at least 3 hours, their digestive absorption may be reduced.
Oxalic acid (found in spinach and rhubarb) and phytic acid (found in whole grains) can inhibit calcium absorption by forming insoluble compounds with calcium ions. The patient should not take any products containing calcium within two hours of eating foods rich in oxalic acid and phytic acid.
Effects on ability to Drive and use machines
No effects on the ability to drive or use machines are expected.
Warnings and Precautions
PRECAUTIONS FOR USE OF CALTRATE VITAMIN D3 600 MG / 400 IU
In the event of prolonged treatment with Caltrate Vitamin D3, it is necessary to have the amount of calcium present in the blood checked regularly (calcemia). This control is particularly important in the elderly and during associated treatment based on cardiac glycosides or diuretics. Depending on the result, your doctor may need to reduce or even interrupt your treatment.
If you frequently have kidney stones.
If your doctor has told you that you have kidney failure.
If your doctor has told you that you have sarcoidosis
If you are immobilized and you have reduced bone mass (osteoporosis)
If you are taking other medicines containing vitamin D3 or calcium
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
During pregnancy, the daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D. Studies in animals have shown reproductive toxicity at high doses of vitamin D. In pregnant women, any overdose of calcium and vitamin D should be avoided because permanent hypercalcemia has been associated with negative effects on fetal development. There is no evidence that vitamin D3 at a therapeutic dose is teratogenic in humans.
Caltrate Vitamin D3 can be administered during pregnancy, in case of calcium and vitamin D3 deficiency.
Feeding with milk
Caltrate Vitamin D3 can be administered during breast-feeding. Calcium and vitamin D3 pass into breast milk. This should be taken into account in the case of concomitant administration of vitamin D3 in children.
What happens if I overdose from Caltrate Vitamine D3 ?
If you take more Caltrate Vitamin D3 than you should and experience any of the symptoms of overdose, stop taking Caltrate Vitamin D3 and contact your doctor immediately .
Possible symptoms of an overdose are: anorexia, excessive thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disorders, increased urine volume, bone pain, kidney stones.
In case of prolonged overdose, calcifications may appear in the blood vessels or tissues.
In cases of large overdoses, cardiac arrest may occur.
What should I do if I miss a dose?
Do not take a double dose to make up for the dose you forgot to take.
If you have further questions on the use of this medicine, ask your doctor or pharmacist for more information.
What happens if you stop taking Caltrate Vitamine D3 ?
Not applicable.
Not applicable.
Not applicable.
What is Forms and Composition ?
VITAMIN D3 CALTRATE 600 MG / 400 IU: COMPOSITION
Active substance
Calcium carbonate: 1498.50 mg
Quantity corresponding to elemental calcium: 600.00 mg
Cholecalciferol or vitamin D3: 400.00 IU
For a scored film-coated tablet.
Other components
Microcrystalline cellulose, povidone, crospovidone, sodium laurilsulfate, croscarmellose sodium, magnesium stearate, OPADRY OY-S-27203, light liquid paraffin, talc.
WHAT IS CALTRATE VITAMIN D3 AND CONTENTS OF THE OUTER PACKAGE?
Gray / beige, oblong film-coated tablet. One of the faces bears a score bar with “D” engraved on the left of the bar, and “600” on the right side. “Caltrate” is printed on the other side.
Bottles of 20, 30, 60, 90 and 180 tablets. Not all presentations may be marketed.
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3kvlwtL via Edrug Online
0 notes
Text
Zymad Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Metabolism and nutrition Active ingredients: Cholecalciferol
what is Zymad ?
This medication is usually prescribed for:
Vitamin D deficiency
what is Zymad medication used for and indication?
It is indicated for the treatment and / or prevention of vitamin D deficiency.
Presentation (s) available for Zymad 200,000 IU
1 ampoule (s) in 2 ml amber glass
FEATURE DESCRIPTION Pharmaceutical class vitamins Active substance (s) for one ampoule: cholecalciferol (200,000 IU) General medicine no Pharmaceutical form drinkable solution Route (s) of administration oral Social security reimbursement rate 65% Laboratory (s) ROTTAPHARM SARL Conditions of issue available by simple prescription
Zymad Dosage
Dosage, Frequency of administration and Duration of treatment
Vitamin deficiency in children
Prophylaxis
Its implementation is:
Imperative in all infants from 0 to 18 months then during the winter period in children up to the age of 5 (ministerial circulars of February 21, 1963 and January 6, 1971),
Recommended for children and adolescents when living conditions include:
insufficient exposure to the sun,
a diet low in vitamin D.
Premature:
It is preferable to administer daily doses in drops
From 0 to 18 months:
Without milk enriched with vitamin D or in children with pigmented skin: 1 vial every 6 months.
From 18 months to the end of adolescence:
Without digestive pathology: 1 ampoule at the beginning of winter
With digestive pathology or receiving anti-convulsants: 1 ampoule every 3 months.
Treatment
1 ampoule, renewable once for 6 months, then resume the usual prophylaxis to prevent relapses. Do not exceed a total dose of 600,000 IU / year.
Vitamin deficiency in adults and the elderly
Prophylaxis
Elderly subject: 1 ampoule every 6 months.
Adult at risk of deficiency (digestive pathology, in an institution, anti-convulsant treatment, etc.): 1 ampoule every 6 months.
Treatment
1 ampoule renewable once or twice over 6 months, then resume the usual prophylaxis to prevent relapses. Do not exceed a total dose of 600,000 IU / year.
Zymad Contraindications
Never take ZYMAD 200,000 IU, oral solution in an ampoule in the event of:
known allergy to vitamin D or any of the other constituents;
hypercalcemia (excess calcium in the blood), hypercalciuria (excess calcium in the urine), calcium lithiasis (kidney stones).
How To Take Zymad ?
Method and / or route (s) of administration
Oral route.
how does Zymad work?
Vitamin D is absorbed in the small intestine passively, then reaches the general circulation by lymphatic route, incorporated into chylomicrons.
After absorption, it binds to a specific carrier protein and is transported to the liver where it is converted into 25-hydroxyvitamin D. This in turn binds to the same carrier protein and is transported to the kidneys where it is. transformed into its active form, 1,25-dihydroxyvitamin D.
Its essential storage sites are adipose tissue, muscles, but also blood. The 25-hydroxyvitamin D bound to its carrier protein is the major circulating reserve form of vitamin D. Its half-life in the blood is 15 to 40 days.
The elimination of vitamin D and its metabolites occurs via the faeces, in unprocessed form or in water-soluble form (calcitroic acid, glycuroconjugate derivatives).
How To Store Zymad ?
Keep this medication out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date refers to the last day of that month.
Store at a temperature not exceeding 25 ° C.
Keep the ampoule in the outer carton in order to protect from light.
Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
Zymad Side Effects
Like all medicines, ZYMAD 200,000 IU oral solution in ampoule can cause side effects, although not everybody gets them.
Skin and subcutaneous tissue disorders: pruritus, rash, erythema, edema.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Zymad Interactions
Combinations subject to precautions for use
+ Enzyme-inducing anticonvulsants
Decrease in vitamin D concentrations more marked than without treatment with inducers.
Determination of vitamin D concentrations and supplementation if necessary.
+ Rifampicin
Decrease in vitamin D concentrations more marked than without treatment with rifampicin.
Determination of vitamin D concentrations and supplementation if necessary.
Associations to take into account
+ Orlistat:
Decreased absorption of vitamin D.
Effects on ability to Drive and use machines
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Warnings and Precautions
To avoid overdose, consider the total doses of vitamin D when combined with treatment already contain this vitamin or if milk using supplemented with vitamin D.
In indications requiring repeated doses, monitor urinary calcium and serum calcium and stop the intake of vitamin D if calcium levels exceed 106 mg / l (2.65 mmol / l) or the calcium exceeds 300 mg / 24 h in adults or 4-6 mg / kg / day in children.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
If needed, vitamin D can be prescribed during pregnancy. ZYMAD 200,000 IU is not a suitable strength for pregnant women.
Ask your doctor or pharmacist for advice before taking any medicine.
Feeding with milk
If needed, vitamin D can be prescribed during breastfeeding. However, this supplementation does not replace the administration of vitamin D in the newborn.
Ask your doctor or pharmacist for advice before taking any medicine.
What happens if I overdose from Zymad ?
f you take more ZYMAD 200,000 IU, oral solution in ampoule than you should:
Immediately consult your doctor or pharmacist.
The clinical signs of an overdose are:
· Headache, fatigue, loss of appetite, weight loss, stunted growth;
· Nausea, vomiting;
Profuse urine, intense thirst, dehydration;
· Kidney stones, calcification of tissues, especially kidney and vessels;
· Renal failure (failure of kidney function).
The biological signs of an overdose are:
· Increase in calcium levels in the blood and urine and increased phosphorus levels in the blood and urine, low concentration and high parathyroid hormone 25-hydroxyvitamin D .
In the event of an overdose, treatment should be stopped, calcium intake (dairy) limited and your doctor should be consulted.
What should I do if I miss a dose?
If you forget to take ZYMAD 200,000 IU, oral solution in ampoule
N o not take a double dose to make up the dose you missed.
What happens if you stop taking Zymad ?
Not applicable.
Not applicable.
Not applicable.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse for more information.
What is Forms and Composition ?
Appearance and shape
Oral solution in ampoule.
2 ml in 5 ml ampoule (type III brown glass) with breakable tip. Box of 1.
Other shapes
ZYMAD 50,000 IU Oral solution box of 1 ampoule of 2 ml
ZYMAD 80,000 IU Oral solution box of 1 ampoule of 2 ml
ZYMAD 10,000 IU / ml, oral solution in drops, box of 1 vial (+ dropper) of 10 ml.
Composition
Active ingredient Drinkable solution Cholecalciferol 200,000 IU *
* per unit dose
Active ingredients: Cholecalciferol
Excipients: Sweet orange essential oil , Oleic macrogolglycerides , Refined olive oilNo excipient with known effect ? is not present in the composition of this drug
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/36N1SVt via Edrug Online
0 notes
Text
Givalex solution for mouthwash Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Stomatology Active ingredients: Hexetidine , Choline salicylate , Chlorobutanol
Medicinal product withdrawn from the market on 15/10/2015
what is Givalex ?
This medication is usually prescribed for:
Oral cavity infection
Postoperative care in stomatology
what is Givalex medication used for and indication?
This medication is a mouthwash.
It is recommended in the local adjunctive treatment of infections of the mouth or in care after surgical intervention of the oral cavity.
Presentation (s) available for Givalex
3 presentations are available for this drug:
1 125 ml amber glass vial (s)
1 125 ml amber glass bottle (s) with polypropylene measuring cup
1 500 ml amber glass vial (s)
FEATURE DESCRIPTION Pharmaceutical class stomatological preparations Active substance (s) per 100 ml of mouthwash solution: hexetidine (0.100 g), choline (salicylate) (0.500 g), chlorobutanol hemihydrate (0.250 g) General medicine no Pharmaceutical form mouthwash solution Route (s) of administration oral route other Social security reimbursement rate 15% Laboratory (s) NORGINE PHARMA Conditions of issue restricted prescription drug
Givalex Dosage
RESERVED FOR ADULTS AND CHILDREN OVER 6 YEARS OLD
Local use in mouthwash.
Do not swallow.
2 to 4 mouthwashes per day, by pouring 10 ml of this product into the measuring cup and completing with water up to the 50 ml mark.
Givalex Contraindications
Never use GIVALEX, solution for mouthwash in the following cases:
Known allergy to hexetidine, chlorobutanol, salicylates or a drug of similar activity (NSAIDs, aspirin).
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK YOUR OPINION OF YOUR DENTIST OR OSTOMATOLOGIST AND / OR YOUR DOCTOR OR PHARMACIST .
How To Take Givalex ?
Administration mode
Use locally as a mouthwash.
Do not swallow.
Duration of treatment
The treatment should not exceed 5 days without medical advice.
how does Givalex work?
Pharmacotherapeutic group:
ANTI-INFECTIOUS MEDICINAL PRODUCTS FOR LOCAL ORAL TREATMENT
ATC CODE: A01AB12 (stomatological preparations)
How To Store Givalex ?
Keep out of the reach and sight of children.
Expiration date
Do not use GIVALEX, solution for mouthwash after the expiry date stated on the outer packaging.
Storage conditions
Store away from light.
If necessary, warnings against certain visible signs of deterioration
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with any unused medicine. These measures will help protect the environment.
Givalex Side Effects
Like all medicines, GIVALEX, mouthwash solution can cause side effects, although not everybody gets them.
Possibility of allergic reactions: irritations, skin reactions.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your dentist or stomatologist and / or your doctor or pharmacist.
Keep out of the reach and sight of children.
Givalex Interactions
Do not use several drugs containing an antiseptic at the same time.
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.
Effects on ability to Drive and use machines
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Warnings and Precautions
Special warnings
DO NOT LEAVE THIS MEDICINE WITHIN THE REACH OF CHILDREN.
Prolonged use (more than 5 days) of this medication is undesirable because it can modify the natural microbial balance of the mouth, throat.
Precautions for use
If symptoms worsen or no improvement after 5 days: CONSULT YOUR DOCTOR.
IN CASE OF DOUBT, DO NOT HESITATE TO ASK FOR THE ADVICE OF YOUR DOCTOR OR PHARMACIST.
PREGNANCY & BREAST-FEEDING & FERTILITY
Use with caution in pregnant or breastfeeding women, for lack of exploitable clinical data.
What happens if I overdose from Givalex ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What should I do if I miss a dose?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if you stop taking Givalex ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What is Forms and Composition ?
Appearance and shape
Lack of information in the MA.
125 ml type III amber glass bottle with measuring cup (polypropylene), closed with a cap fitted with a low density polyethylene seal.
Other shapes
GIVALEX, solution for mouthwash, 125 ml bottle
GIVALEX, mouthwash, 50 ml spray bottle
Composition
Active ingredient Mouthwash solution Hexetidine 0.1 g * Choline salicylate 0.5 g * Chlorobutanol 0.25 g *
* per unit dose
Active ingredients: Hexetidine , Choline salicylate , Chlorobutanol
Excipients: Sodium saccharin , Polysorbate 20 , Propionic acid , 96% ethanol (alcohol) , Purified water , Lemon aroma composed: Lemon essential oil , Anise essential oil , Lime essential oil , Menthol , Cineole , Methyl salicylate in solution in , Alcohol
No excipient with known effect ?
is not present in the composition of this drug
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3kqkkI1 via Edrug Online
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PANSORAL, gel for oral application Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Stomatology active ingredients: Choline salicylate , Cetalkonium chloride
what is PANSORAL, gel ?
This medication is usually prescribed for:
Inflammatory condition of the oral mucosa
Ulcerative condition of the oral mucosa
what is PANSORAL, gel medication used for and indication?
This medication is recommended for the short-term adjunctive treatment of pain associated with inflammatory and ulcerative states of the oral mucosa.
Presentation (s) available for Pansoral
8 presentations are available for this drug:
1 polypropylene tube (s) of 3 g
1 polypropylene tube (s) of 5 g
1 polypropylene tube (s) of 12 g
1 polypropylene tube (s) of 15 g
1 polypropylene tube (s) of 30 g
1 polyethylene tube (s) of 3 g
1 polyethylene tube (s) of 15 g
1 polyethylene tube (s) of 30 g
FEATURE DESCRIPTION Pharmaceutical class stomatological preparations Active substance (s) per 100 g: choline salicylate (8.7 g), cetalkonium chloride (0.01 g) General medicine no Pharmaceutical form gel for application Route (s) of administration gingival Selling price unregulated price Social security reimbursement rate 0% Laboratory (s) Laboratory (s) manufacturer Pansoral Conditions of issue available without prescription
PANSORAL, gel Dosage
Pansoral: dosage
This medicine is only for adults.
Strict local use. Gingival application.
Clean and dry prosthetic devices before application.
On average, 1 to 4 applications (the value of a dab of gel) per day.
In the case of permanent prostheses: deposit the value of a pea of gel on the incisors or molars next to the painful gum.
In the case of temporary prostheses: place the gel on the part of the device corresponding to the extractions.
Once in the mouth, the gel spreads evenly under the effect of temperature and chewing.
PANSORAL, gel Contraindications
Never use PANSORAL, gel for oral application in the following cases:
history of allergy to salicylate drugs (aspirin.)
IF IN DOUBT, IT IS ESSENTIAL TO ASK YOUR DENTAL SPECIALIST FOR THE ADVICE.
how does PANSORAL, gel work?
Pharmacotherapeutic group PREPARATIONS FOR STOMATOLOGY / OTHER AGENTS FOR LOCAL TREATMENT, ATC code: A01 AD11 (A: Digestive system and metabolism).
Choline salicylate is a very water-soluble compound, quickly absorbed by the mucous membrane, its analgesic effect is manifested in a few minutes.
Cetalkonium chloride, a quaternary ammonium compound, inhibits the growth of Gram + and Gram – bacteria, and also has an antifungal action.
How To Store PANSORAL, gel ?
Keep this medication out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date refers to the last day of that month.
No special storage conditions.
Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
PANSORAL, gel Side Effects
Like all medicines, PANSORAL gel for oral application can cause side effects, although not everybody gets them.
Hypersensitivity reactions to salicylate drugs,
Risk of irritation due to the presence of alcohol.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
PANSORAL, gel Interactions
Use of other drugs
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.
Effects on ability to Drive and use machines
PANSORAL, gel for oral application has no effect on the ability to drive and use machines.
The result of the breathalyzer can be positive within ten minutes after application of the oral gel (increase in exhaled alcohol in the air, without systemic passage).
Warnings and Precautions
Special warnings
THIS MEDICINE IS ONLY FOR ADULTS.
If there is no improvement after a few days, see your dental specialist. In fact, irritation due to your prosthesis may require it to be adapted and the application of this treatment only constitutes a waiting gesture.
WARNING, THIS MEDICINE CONTAINS 39 G OF ALCOHOL PER 100 g.
Precautions for use
IF IN DOUBT, IT IS ESSENTIAL TO ASK YOUR DENTAL SPECIALIST FOR THE ADVICE.
PREGNANCY & BREAST-FEEDING & FERTILITY
This product can be administered during pregnancy and lactation if needed.
What happens if I overdose from PANSORAL, gel ?
If you have used more PANSORAL, gel for oral application than you should:
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What should I do if I miss a dose?
If you forget to use PANSORAL, gel for oral application:
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if you stop taking PANSORAL, gel ?
If you stop using PANSORAL, gel for oral application:
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
If you have further questions on the use of this medicine, ask your doctor or pharmacist for more information.
What is Forms and Composition ?
Appearance and shape
Oral gel.
Tube (polyethylene) closed with a 15 g polypropylene stopper.
WHAT IS PANSORAL, GEL FOR ORAL APPLICATION AND CONTENTS OF THE OUTER PACKAGING ?
This medication is in the form of an oral gel. Box of 1 tube of 3, 5, 12, 15 or 30 g.
Not all presentations may be marketed.
Composition
Active ingredient Mouth gel Choline salicylate 8.7 g * Cetalkonium chloride 0.01 g *
* per unit dose
Active ingredients: Choline salicylate , Cetalkonium chloride
Excipients: Ethanol 96% , Glycerol , Methylcellulose , Sodium hydroxide 32% solution , Star anise essential oil , Purified water
No excipient with known effect ?
is not present in the composition of this drug
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/2IAuzMy via Edrug Online
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Text
Alkocortenbioform , cream Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Dermatology Active ingredients: Flumetasone , Clioquinol
Drug withdrawn from the market on 08/24/2018
what is Alkocortenbioform cream ?
This medication is usually prescribed for:
Contact eczema
Atopic dermatitis
Stasis dermatitis
Psoriasis
Seborrheic dermatitis except the face
Insect bite
Parasitic prurigo
what is Alkocortenbioform cream used for and indication?
This medicine contains a corticosteroid of moderate activity and an antiseptic.
It is indicated for certain skin conditions such as contact eczema, atopic dermatitis, but your doctor may prescribe it in other cases.
Presentation (s) available for Alkocortenbioform
1 tube (s) painted aluminum of 15 g
FEATURE DESCRIPTION Pharmaceutical class not communicated Active substance (s) per 100 g of cream: clioquinol (3,000 g), flumetasone pivalate (0.020 g) General medicine no Pharmaceutical form cream Route (s) of administration cutaneous Selling price unregulated price Social security reimbursement rate 0% Laboratory (s) Laboratory (s) manufacturer Alkocortenbioform Conditions of issue available by simple prescription
Alkocortenbioform Dosage
The dosage is 1 to 2 applications per day in a thin layer, followed by a light massage. Do not increase the number of applications per day.
Alkocortenbioform Contraindications
Never use ALKOCORTENBIOFORM, cream in the following cases:
allergy to any component of the drug
ulcerated lesions
acne
rosacea
infectious diseases of the skin of viral (herpes, shingles, chickenpox, etc.), bacterial (example: impetigo, etc.), mycotic (due to microscopic fungi) or parasitic origin.
application on the eyelids
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.
How To Take Alkocortenbioform ?
Method and route of administration
DERMAL
It is advisable to apply the product in spaced strokes, then to spread it by massaging lightly until it is fully absorbed.
Wash hands after application.
Frequency of administration
1 to 2 applications per day as prescribed by your doctor
Duration of treatment
The treatment will be stopped gradually, by spacing out the applications and / or by using a less strong or less dosed corticosteroid.
Strictly follow your doctor’s prescription and do not prolong the treatment.
how does Alkocortenbioform work?
Association of a moderate activity DERMOCORTICOIDE and an ANTISEPTIC.
(D: dermatology).
Topical corticosteroids are classified into 4 activity levels according to skin vasoconstriction tests: very strong, strong, moderate, weak activity.
Locacortene Vioforme contains a corticosteroid of moderate activity and an antiseptic, clioquinol.
Flumetasone pivalate is the essential active substance.
Active on certain inflammatory processes (for example: contact hypersensitivity) and the pruritic effect which is linked to them. Vasoconstrictor. Inhibits cell multiplication.
How To Store Alkocortenbioform ?
Keep out of the reach and sight of children.
Expiration date
Do not use ALKOCORTENBIOFORM, cream after the expiry date stated on the outer packaging.
Storage conditions
Store at a temperature below 25 ° C.
If necessary, warnings against certain visible signs of deterioration
Medicines must not be disposed of via wastewater or household waste. Ask your pharmacist what to do with any unused medicine. These measures will help to protect the environment.
Alkocortenbioform drug Side Effects
Like all medicines, ALKOCORTENBIOFORM, cream can cause side effects, although not everybody gets them:
Due to the presence of a corticosteroid
With prolonged use, there is a risk of thinning and fragility of the skin, dilation of small blood vessels, stretch marks, acne breakout.
Cases of exaggerated development of the hair system, discoloration of the skin, secondary infection in particular in the event of treatment under an occlusive dressing or in the folds, have been reported.
Due to the presence of the antiseptic:
Skin allergy
Yellowish discoloration of the skin disappearing quickly.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Alkocortenbioform Interactions
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.
Effects on ability to Drive and use machines
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Warnings and Precautions
WARNINGS
The prolonged use on the face of corticosteroids with moderate activity exposes to the occurrence of corticosteroid-induced and paradoxically corticosensitive dermatitis, with rebound after each stop. A gradual weaning, particularly difficult, is then necessary.
Due to the passage of the corticosteroid into the systemic circulation, treatment over large areas or under occlusion may cause the systemic effects of systemic corticosteroid therapy, particularly in infants and toddlers. They consist of a cushingoid syndrome and a slowing of growth. These accidents disappear when treatment is stopped, but abrupt cessation can be followed by acute adrenal insufficiency.
PRECAUTIONS FOR USE
In infants, it is preferable to avoid corticosteroids of moderate activity. One should be particularly wary of spontaneous occlusion phenomena which may occur in the folds or under the layers.
In the event of a bacterial or mycotic infection of a corticosensitive dermatosis, precede the use of the corticosteroid with a specific treatment.
If a local intolerance appears, the treatment must be interrupted and the cause must be sought.
Breast-feeding: during oral treatment, breast-feeding should be avoided because corticosteroids are excreted in breast milk. By local route, the transdermal passage and therefore the risk of excretion of the corticosteroid in the milk will depend on the surface treated, the degree of epidermal damage and the duration of treatment.
TATE TO ASK FOR THE ADVICE OF YOUR DOCTOR OR YOUR PHARMACIST.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
No teratogenicity studies have been performed with topical corticosteroids.
However, studies concerning the intake of oral corticosteroids have not revealed a higher risk of malformation than that observed in the general population.
Breast-feeding
During oral treatment, breast-feeding should be avoided because corticosteroids are excreted in breast milk.
By local route, the transdermal passage and therefore the risk of excretion of the corticosteroid in the milk will depend on the surface treated, the degree of epidermal damage and the duration of treatment.
What happens if I overdose from Alkocortenbioform ?
If you use more ALKOCORTENBIOFORM, cream than you should:
Always use ALKOCORTENBIOFORM, cream as your doctor has told you.
Excessive or prolonged use of topical corticosteroids may be the cause of exacerbation of undesirable effects, and systemic passage is not excluded.
In case of systemic overdose, appropriate symptomatic treatment is indicated. If you have used more ALKOCORTENBIOFORM, cream than you need, contact your doctor.
What should I do if I miss a dose?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if you stop taking Alkocortenbioform ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What is Forms and Composition ?
Appearance and shape
Lack of information in the MA.
15 g sealed aluminum tube coated internally with epoxyphenolic varnish and closed with a high density polyethylene stopper.
Composition
Active ingredient Cream Flumetasone 0.02 g * Clioquinol 3 g *
* per unit dose
Active ingredients: Flumetasone , Clioquinol
Excipients with known effects ?
Cetyl alcohol, Stearyl alcohol
Other excipients: Synthetic whale white, Vaseline, Glycerol, Sodium lauryl sulfate, Purified water
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/2IBq8S2 via Edrug Online
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Text
MEDIATOR Uses, Dosage, Side Effects, Precautions & Warnings
mediator medicine >> Generic drug of the Therapeutic class: Metabolism and nutrition Active ingredients: Benfluorex
what is mediator medicine for and indication?
MEDIATOR,Adapted diet adjunct in diabetics with overweight.
MEDIATOR 150 mg, coated tablet, pack of 100
MEDIATOR Dosage
Oral way.
The dosage is usually 3 tablets a day. This dosage may be prescribed from the outset or progressively achieved as follows:
1 st week: 1 tablet daily, during dinner;
2nd week: 2 tablets daily, 1 during lunch, 1 during dinner;
From the 3 rd week: 3 tablets per day, 1 breakfast, 1 lunch, 1 dinner.
Depending on the biological results, the dosage can be decreased to 2 tablets per day, or even 1 tablet per day.
In combination with a suitable diet, Mediator is an adjuvant treatment: regular clinical and biological monitoring of each patient will be established.
How it works MEDIATOR?
Pharmacotherapeutic group: other antidiabetics except insulin
ATC Code: A10BX06
Picks of action on carbohydrate metabolism:
In animals, the following effects have been observed:
Facilitating the penetration and cellular use of glucose (rat);
Decreased hyperglycemia in the diabetic rat (insulin proprio or not), decreased hyperglycemia (measured by HPO area) in the rabbit.
Mediator has no action on insulin secretion; the occurrence of hypoglycemia is unlikely.
Additional effect of Picks:
A decrease in serum uric acid level of approximately 14% was observed in patients with hyperuricemic obesity treated with Pediatric in combination with a suitable diet.
MEDIATOR Side Effects
The following side effects have been observed:
Digestive disorders (nausea, vomiting, gastralgia, diarrhea), asthenia, drowsiness or dizziness. However, they are observed more particularly at dosages greater than 3 tablets per day and vary according to the individual susceptibilities;
Very rare cases of anaphylactic reactions, hypotension, shock, skin rash, urticaria, Quicke’s edema;
Elevation of liver enzymes, hepatitis (very rare).
Confusion, cognitive function disorders: Tempo-spatial disorientation, behavioral disorders: agitation, delirium, hallucinations perception disorders (very rare).
MEDIATOR Interactions
Not applicable.
MEDIATOR Warnings and Precautions
The metabolic disorders associated with a treatment with Picks are mainly observed in adults. Prescription Mediator is not justified in children.
If, after a period of administration of a few months (3 to 6 months), a satisfactory decrease in serum glucose concentrations is not obtained, additional or different therapeutic means should be considered.
The attention of athletes will be drawn to the fact that this specialty contains an active ingredient that can induce a positive reaction tests conducted during doping controls.
Due to the presence of sucrose, this drug should not be used in cases of fructose intolerance, glucose-galactose malabsorption syndrome or sucrase-isomaltase deficiency.
Drive and use machines
Drivers’ attention is drawn to the drowsiness that may occur when using this medication.
MEDIATOR and PREGNANCY / BREAST FEEDING / FERTILITY
Pregnancy
Studies in animals have not shown any teratogenic effect. In the absence of teratogenic effect in animals, a malformative effect in the human species is not expected. Indeed, to date, the substances responsible for malformations in the human species have proved teratogenic in animals in well conducted studies on two species.
Clinically, there are currently no data of sufficient relevance to evaluate the possible malformative or foetotoxic effect of benfluorex when administered during pregnancy.
Therefore, as a precaution, it is best not to use this medicine during pregnancy. In case of accidental exposure, this treatment should be discontinued.
feeding
In the absence of data on the passage of benfluorex in breast milk, this drug is not recommended during breastfeeding
What happens if I overdose from MEDIATOR ?
In case of massive absorption, the treatment will only be symptomatic: stomach lavage, osmotic diuresis, correction of possible electrolyte disorders, monitoring of blood pressure, state of consciousness as well as respiratory and cardiac functions.
What is Forms and Composition MEDIATOR ?
Appearance and shape
White coated domed stick tablet.
100 tablets in blister packs (PVC-Aluminum)
Other shapes
MEDIATOR 150 mg, coated tablet, box of 30
Composition
Active ingredient Coated tablet Benfluorex 150 mg *
* per unit dose
Active ingredients: Benfluorex
Excipients: Corn starch , Sodium bicarbonate , Carmellose sodium , White beeswax , Titanium dioxide , Ethylcellulose , Glycerol mono-oleate , Polysorbate 80 , Povidone , Sucrose , Colloidal anhydrous silica , Magnesium stearate , TalcNo excipient with known effect ? is not present in the composition of this drug
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3g3QN4N via Edrug Online
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Text
Diprosalic ointment,Lotion Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Dermatology active ingredients: salicylic acid, betamethasone , dipropionate
what is Diprosalic ?
Corticosteroid-sensitive dermatoses (skin diseases) with a keratotic component (with thickening of the skin or scaly skin.
Dermatoses located more particularly on the scalp, in the hairy regions and the folds.
what is diprosalic ointment used for and indication?
Corticosteroid-sensitive dermatoses with a keratotic or squamous component:
Preferred indications where local corticosteroid therapy is considered the best treatment:
Lichenification.
Indications where corticosteroid therapy is one of the usual treatments:
·psoriasis,
·lichen,
Seborrheic dermatitis except the face.
PRESENTATION (S) AVAILABLE FOR DIPROSALIC
3 presentations are available for this drug:
1 polyethylene bottle (s) of 15 g
1 polyethylene bottle (s) of 30 g
1 polyethylene bottle (s) of 100 g
FEATURE DESCRIPTION Pharmaceutical class corticosteroids, dermatological preparations Active substance (s) per 100 g: salicylic acid (2 g), betamethasone dipropionate (0.064 g) General medicine no Pharmaceutical form lotion Route (s) of administration cutaneous Social security reimbursement rate 15% Laboratory (s) MSD FRANCE Conditions of issue available by simple prescription
Diprosalic Dosage
Applications will be limited to 2 per day for one to two weeks; in maintenance treatment, a single daily application may be sufficient. An increase in the number of applications could worsen the side effects without improving the therapeutic effects.
The treatment of large surfaces requires special monitoring (number of tubes used).
The treatment will be stopped gradually by spacing out the applications or by using a less strong or less dosed corticosteroid or alternating with a base without a dermocorticoid.
Diprosalic Contraindications
Never use DIPROSALIC, lotion in the following cases:
allergy (hypersensitivity) to the active substance or to any of the ingredients of DIPROSALIC lotion,
ulcerated lesions,
acne,
rosacea (rosacea),
infectious skin diseases of viral (herpes, shingles, chickenpox), bacterial (example: impetigo, etc.), mycotic (due to microscopic fungi) or parasitic origin,
in infants,
DIPROSALIC is not intended for ophthalmic use.
IF IN DOUBT, YOU MUST ASK FOR THE ADVICE OF YOUR DOCTOR OR YOUR PHARMACIST.
How To use Diprosalic ?
Dermal.
It is advisable to apply the medicine in spaced areas, then to spread it with a plastic glove. In scalp conditions, the lotion will be applied line by line, well beyond the surface to be treated. In case of manual use, wash hands after application.
Duration of treatment
Usually the treatment will be short. The treatment will be stopped gradually by spacing out the applications and / or by the use of a less strong or less dosed corticosteroid.
Prolonged use, use on the face or in children should be subject to strict medical supervision.
how does Diprosalic work?
Pharmacotherapeutic group: Corticosteroids with strong activity, other combinations, ATC code: D07XC01
DIPROSALIC is a strong potency dermocorticosteroid (class II) combined with salicylic acid.
The topical corticosteroid is active on the inflammatory process and the pruritic effect associated with it.
It has vasoconstrictive (anti-perspirant) properties and inhibits cell multiplication and synthesis processes in the dermis and epidermis.
Keratolytic action of salicylic acid.
How To Store Diprosalic ?
Ointment
The duration of the conversation :
36 months.
Lotion
The duration of the conversation :
18 months.
Store at a temperature not exceeding 25 ° C.
After first opening:
6 weeks.
Diprosalic Side Effects
Like all medicines, DIPROSALIC, lotion can cause side effects, although not everybody gets them.
appearance or worsening of rosacea (see “Never use DIPROSALIC, lotion in the following cases”),
delayed healing of wounds, bedsores (rubbing lesions of the skin), leg ulcers (black scab surrounded by a red inflammatory area),
possible effects due to the passage of part of the active ingredients in the blood (see “Special warnings”)
cases of hypertrichosis (abnormal development of the hair system), depigmentation, secondary infections, in particular in the event of treatment under an occlusive dressing or in the folds, have been reported.
In case of prolonged use, on large surfaces, there is a risk of thinning and fragility of the skin, dilation of small blood vessels, stretch marks, acne breakout, redness and irritation around the mouth.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Diprosalic Interactions
Use of other drugs:
Based on local use of this product: At recommended doses, betamethasone for topical use is not likely to cause medically significant drug interactions.
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.
Effects on ability to Drive and use machines
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Warnings and Precautions
Take special care with DIPROSALIC, lotion:
Special warnings
Do not apply on mucous membranes or in the eyes.
It is necessary to avoid the applications on large surfaces, under a dressing, under a diaper or in the folds, in particular in the children, because of possible passage of part of the active principles in the blood.
Precautions for use
This medication should be used in accordance with the doctor’s advice:
exact location of applications,
treatment in children under 12 must be subject to strict medical supervision,
do not apply to the face, except when prescribed by your doctor.
The following recommendations should be followed:
avoid prolonged application on the face, in the folds,
any local irritation or infection should be reported to your doctor,
if an intolerance reaction appears, the treatment should be stopped,
if use under occlusion is necessary, it should be monitored due to the risk of superinfection.
IF IN DOUBT, DO NOT HESITATE TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
Clinical data from a large number of pregnancies exposed by the systemic route to corticosteroids have not shown an increase in the overall rate of malformations, although studies in animals by the systemic route have shown a teratogenic effect.
In humans, no particular malformative effects have been reported with salicylic acid. Fetal toxicity reported with NSAIDs is not expected with Diprosalic given the very low systemic concentrations under normal conditions of use.
The use of Diprosalic during pregnancy can be envisaged in strict compliance with the conditions of use: application to a skin surface <10% of the body surface, treatment duration limited to 4 weeks.
The mother may experience a prolonged bleeding time as well as the newborn if treated until delivery.
Feeding with milk
Corticosteroids and salicylic acid pass into the milk. Due to topical use, Diprosalic can be administered during breast-feeding.
Do not apply on the breasts.
What happens if I overdose from Diprosalic ?
Symptoms
Excessive or prolonged use of topical corticosteroids may lead to inhibition of the hypothalamic-pituitary axis resulting in secondary adrenal insufficiency and be the cause of manifestations of hypercorticism, including Cushing’s disease.
Excessive or prolonged use of topical preparations containing salicylic acid may cause symptoms of salicylic intoxication.
Treatment
Appropriate symptomatic treatment is indicated. Symptoms of acute hypercorticism are usually reversible. Correct electrolyte disturbances if necessary.
In the event of chronic toxicity, a gradual stopping of corticosteroids is advised. Treatment of salicylate poisoning is symptomatic.
Salicylic acid must be eliminated quickly. Orally administer sodium bicarbonate solution to alkalinize the urine and increase diuresis.
What should I do if I miss a dose?
Do not apply a double dose to make up for the dose you forgot to take.
What happens if you stop taking Diprosalic ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
If you have further questions on the use of this medicine, ask your doctor or pharmacist for more information.
What is Forms and Composition ?
SHAPES and PRESENTATIONS
Ointment: Tube of 30 g.
Lotion: Bottle of 30 g.
COMPOSITION
Ointment: p tube Betamethasone 15 mg (as micronized betamethasone dipropionate: 19.2 mg / tube) Salicylic acid 900 mg
Excipients: thick petrolatum oil, white petrolatum.
Lotion: p bottle Betamethasone 15 mg (as betamethasone dipropionate: 19.2 mg / tube) Salicylic acid 600 mg
Excipients: hydroxypropylmethylcellulose, sodium hydroxide, sodium edetate, isopropyl alcohol, purified water.
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/36wxDSr via Edrug Online
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Betadine mouthwash Uses, Dosage, Side Effects,Warnings and Precautions
Betadine mouthwash Generic drug of the Therapeutic class: Dermatology active ingredients: Povidone iodine , Ethanol
what is betadine mouthwash ?
This medicine is an antiseptic solution (containing iodine) for mouthwash.
It is an adjunctive local treatment for infections of the oral cavity and it allows post-operative care in stomatology.
What is Betadine used for and indication?
Adjunctive local treatment of infections of the oral cavity and postoperative care in stomatology.
betadine mouthwash dosage
RESERVED FOR ADULTS AND CHILDREN OVER 6 YEARS OLD.
Local use in mouthwash.
DO NOT SWALLOW.
Four mouthwashes per day, after diluting 1 to 2 teaspoons of the product in a glass of lukewarm water.
Contraindications
Povidone hypersensitivity
Pregnancy from the 2nd trimester
Feeding with milk
Premature
Newborn (0 to 1 month)
Child from 1 month to 6 years old
This medication MUST NOT BE USED in the following situations:
History of hypersensitivity to any of the constituents, in particular povidone. There are no cross reactions with iodinated contrast media. Intolerance reactions (anaphylactoid reactions) to iodine contrast products or seafood anaphylaxis do not constitute a contraindication to the use of BETADINE.
Premature and Newborn (under 1 month).
In order extended for the second and third trimester of pregnancy.
Breastfeeding is against-indicated in cases of prolonged treatment.
This medication SHOULD NOT GENERALLY BE USED:
In children under 6 years.
how does betadine work
PREPARATIONS FOR ODONTOSTOMATOLOGY / OTHER AGENTS FOR LOCAL / VARIOUS ORAL TREATMENT.
ATC Code: A01AD11.
Povidone iodine is an iodophoric product.
It is an organic complex composed of about 10% active iodine available.
Its spectrum of activity is that of iodine (antiseptic bactericide on all bacteria and fungicide on yeasts and filamentous fungi).
What are the side effects of Betadine?
Exceptionally, hypersensitivity reactions: urticaria, angioedema, anaphylactic shock, anaphylactoid reaction, have been described with products containing povidone, including specialties BETADINE.
Possibility of irritation manifesting itself in the mucous membranes.
In case of repeated administrations and excessive use, this product may, on the one hand be irritating to the mucous membranes, on the other hand it can occur iodized overload likely to cause thyroid dysfunction.
Due to the presence of terpene derivatives and in case of non-compliance with the recommended doses, possibility of agitation and mental confusion in the elderly.
Betadine Interactions
RECOMMENDED ASSOCIATIONS :
Mercurial antiseptics : erythema, phlyctenes, and even mucocutaneous necrosis (formation of a caustic complex when concomitant use of iodized and mercurial antiseptics).
The interaction depends on the stability of the organomercurial at the cutaneous level and the individual sensitivity.
Betadine Warnings and Precautions
Caution
If symptoms persist for more than 5 days and / or associated fever, the course of action should be evaluated again.
Due to possible absorption of iodine through the mucosa, repeated or prolonged treatment may pose a risk of systemic effects , particularly thyroid dysfunction.
In case of a history of epilepsy, take into account the presence of terpene derivatives (mint flavor).
Precautions for use
The indication does not justify a prolonged treatment, especially as it could expose to an imbalance of the normal microbial flora of the oral cavity with a risk of bacterial or fungal diffusion.
Given the possible interference (antagonism, inactivation), the simultaneous or successive use of antiseptics should be avoided.
Possible interference with functional exploration of the thyroid
Drive and use machines
Not applicable.
Betadine and PREGNANCY / BREAST FEEDING / FERTILITY
Pregnancy
Studies in animals have not shown any teratogenic effect.
In the absence of teratogenic effect in animals, a malformative effect in the human species is not expected. Indeed, to date, the substances responsible for malformations in humans have been teratogenic in animals in well-conducted studies on two species.In clinical practice, there are currently no data of sufficient relevance to evaluate the possible malformative effect of povidone iodine when administered at 1
trimester of pregnancy:
Since the fetal thyroid begins to fix iodine after 14 weeks of amenorrhea, no repercussions on the fetal thyroid are expected in case of prior administrations.
Iodine overload, very likely with prolonged use of this product after this term, can lead to fetal hypothyroidism, biological or even clinical (goiter).
Consequently, prolonged use of this drug is against-indicated from 2 e quarter. Its use, on an ad hoc basis, should only be considered if necessary.
Breastfeeding:
In case of breastfeeding, it is preferable not to use this drug due to the absence of kinetic data on the passage of terpene derivatives in milk and the potential neurological toxicity on the infant.Iodine passes into breast milk at concentrations higher than maternal plasma.
Because of the risk of hypothyroidism in infants, breastfeeding is contraindicated in case of prolonged treatment with this drug.
What should I do if I miss a dose?
do not take a double dose to make up for it. Resume the normal course of your treatment.
What happens if I overdose from Betadine ?
overdose is not expected under normal conditions of use.
In case of massive oral ingestion likely to lead to serious intoxication, it is to be treated in a specialized environment: gastrointestinal and / or electrolytic disorders, especially in patients with renal insufficiency. Monitoring of thyroid function is recommended.
What is Forms and Composition Betadine?
FORMS and PRESENTATIONS
Solution for mouthwash: 125 ml bottle. Solution for mouthwash and gargle: 10 ml single dose containers, box of 10.
COMPOSITION
p bottle of 125 ml single dose of 10 ml Povidone iodine 12.5 g 1 g
Excipients (common): 85% glycerol, mint flavor (mint essential oil, alcohol), sodium saccharin, sodium hydroxide, purified water.
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/3gtuMNa via Edrug Online
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temgesic 0.2 mg sublingual tablet Uses, Dosage, Side Effects, Precautions & Warnings
temgesic 0.2 mg sublingual tablet >> Generic drug of the Therapeutic class: Analgesics active ingredients: Buprenorphine
what is temgesic 0.2 mg sublingual tablet ?
This medication is an analgesic (it relieves pain).
what is temgesic medication used for and indication?
This medication is recommended for severe pain, in particular that which is resistant to other analgesic drugs (for example following certain surgical procedures).
PRESENTATION (S) AVAILABLE FOR TEMGESIC 0.2 MG
8 presentations are available for this drug:
High density polyethylene (HDPE) bottle (s) of 20 tablet (s)
High density polyethylene (HDPE) bottle (s) of 30 tablet (s)
High density polyethylene (HDPE) bottle (s) of 50 tablet (s)
High density polyethylene (HDPE) bottle (s) of 100 tablet (s)
nylon aluminum uPVC blister pack (s) of 20 tablet (s)
nylon aluminum uPVC blister pack (s) of 30 tablet (s)
nylon aluminum uPVC blister pack (s) of 50 tablet (s)
nylon aluminum uPVC blister pack (s) of 100 tablet (s)
FEATURE DESCRIPTION Pharmaceutical class pain relievers Active substance (s) for one tablet: buprenorphine (hydrochloride) (0.216 mg) General medicine no Pharmaceutical form compressed Route (s) of administration sublingual Social security reimbursement rate 65% Laboratory (s) RB PHARMACEUTICALS FRANCE Conditions of issue available by simple prescription
temgesic Dosage
The dosage should be adjusted according to the intensity of the pain.
In adults: 1 to 2 tablets per dose, on average 3 times per day.
In subjects over 65 years of age and in particular over 80 years: the dosage should be reduced by half.
For older children aged 7 to 15: 1 to 2 tablets per 24 hours, depending on weight, under careful medical supervision.
STRICTLY COMPLY WITH THE MEDICAL PRESCRIPTION.
temgesic Contraindications
Never use TEMGESIC 0.2 mg sublingual tablet in the following cases:
known allergy to buprenorphine or to any of the ingredients of this medication,
children under 7,
severe respiratory failure,
severe liver disease,
acute alcohol poisoning and alcohol withdrawal syndrome (delirium tremens),
treatment with other morphine analgesics.
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.
How do you take Temgesic?
Method and route of administration
Sublingual route.
The tablets should not be swallowed or chewed: place them under the tongue and allow them to dissolve slowly.
Frequency of administration
STRICTLY COMPLY WITH THE MEDICAL PRESCRIPTION.
Duration of treatment
STRICTLY COMPLY WITH THE MEDICAL PRESCRIPTION.
how does temgesic work?
After sublingual administration of 0.4 mg of buprenorphine, the drug is dosed in plasma from the 30 th minute and the peak plasma concentration is reached within 2 to 3 hours.
The absolute bioavailability is of the order of 75%.
The biotransformation of buprenorphine takes place in the liver where it undergoes N-dealkylation and glucuronoconjugation.
Excretion of buprenorphine occurs primarily in the bile and stool.
How To Store temgesic ?
Keep this medication out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and blister, EXP. The expiration date refers to the last day of that month.
Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
temgesic Side Effects
Like all medicines, TEMGESIC 0.2 mg sublingual tablets can cause side effects, although not everybody gets them.
The following side effects have been observed:
Common side effects (1% -10%): constipation, nausea, vomiting, insomnia, headache, malaise and dizziness, fatigue, drowsiness, drop in blood pressure when changing from lying or sitting to lying down or sitting down standing, sweating.
Rare side effects (0.01% -0.1%): respiratory failure, hallucinations, hepatitis (liver damage) with jaundice.
Other reported side effects: hypersensitivity reactions (allergy), such as rash, pruritus (itching), bronchospasm (bronchial spasm), angioedema (swelling of the face and neck which may cause breathing difficulties) and anaphylactic shock ( severe generalized allergic reaction).
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
temgesic Interactions
Contraindicated associations
Level III morphine agonists ( alfentanil, dextromoramide, fentanyl, hydromorphone, morphine, oxycodone, pethidine, phenoperidine, remifentanyl, sufentanil )
Decrease in the analgesic effect by competitive blocking of receptors, with the risk of the appearance of a withdrawal syndrome.
Not recommended associations
Other morphine analgesics
Decrease in the analgesic effect by blocking the receptors with the risk of the appearance of a withdrawal syndrome.
Alcohol
Alcohol enhancement of the sedative effect of buprenorphine; impaired alertness can make driving and using machines dangerous.
Avoid taking alcoholic drinks and drugs containing alcohol.
Associations to take into account
Benzodiazepines
Increased risk of respiratory depression, which may be fatal in case of overdose.
Other sedative drugs:
morphine derivatives (analgesics, cough suppressants and substitution treatments), neuroleptics, barbiturates, benzodiazepines, anxiolytics other than benzodiazepines (eg meprobamate), hypnotics, sedative antidepressants (amitriptyline, doxepine, mirtiprazine, mirtazamine, ), sedative H 1 antihistamines , central antihypertensive drugs, baclofen and thalidomide:
Increase in central depression. Impaired vigilance can make driving and using machines dangerous.
Combinations subject to precautions for use
CYP3A4 inhibitors ( amprenavir and by extrapolation fosamprenavir, alazanavir, itraconazole, ketoconazole, nelfinavir, ritonavir )
Increase in buprenorphine concentrations due to a decrease in its hepatic metabolism, with the risk of an increase in its adverse effects. Clinical monitoring and dosage adjustment of buprenorphine during treatment with the protease inhibitor and, if necessary, after its discontinuation.
Effects on ability to Drive and use machines
Attention is drawn, especially among vehicle drivers and users of machines, to the risk of drowsiness associated with the use of this medication.
Warnings and Precautions
Special warnings
This medicine can cause psychological and physical dependence during prolonged treatment.
This drug can cause drowsiness which may be increased by products such as alcoholic drinks, tranquilizers, sedative drugs, sleeping pills.
This medicine contains lactose. Its use is not recommended in patients with lactose intolerance (a rare hereditary disease).
Precautions for use
In case of surgery, tell the anesthesiologist to take this medication.
IN CASE OF DOUBT, DO NOT HESITATE TO ASK FOR THE ADVICE OF YOUR DOCTOR OR YOUR PHARMACIST.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
Clinically, there is currently no sufficiently relevant data to assess a possible malformative or fetotoxic effect of buprenorphine when it is administered during pregnancy.
However, given the expected benefit to the mother, buprenorphine may be prescribed during pregnancy.
During the last three months of pregnancy, chronic use of buprenorphine by the mother, regardless of the dose, can cause withdrawal syndrome in the newborn.
In addition, at the end of pregnancy, high doses of buprenorphine, even in brief treatment, are liable to cause respiratory depression in the newborn.
Consequently, at the end of pregnancy in the event of occasional high doses or chronic administration of buprenorphine, neonatal monitoring should be considered because of a theoretical risk of respiratory depression or withdrawal syndrome in the newborn. .
Feeding with milk
Due to the passage of buprenorphine and its metabolites in breast milk and insufficient clinical data, it is preferable as a precaution to avoid breast-feeding in case of maternal treatment.
What happens if I overdose from temgesic ?
Despite a large safety margin, overdose can occur with high dosages.
In the event of accidental overdose, comprehensive management should be instituted, including close monitoring of the patient’s respiratory and cardiac status. The main symptom to be treated is respiratory depression, which can lead to respiratory arrest and death. If the patient vomits, precautions should be taken to avoid bronchial inhalation of digestive contents.
Treatment :
Symptomatic treatment of respiratory depression by appropriate means should be initiated. Freedom of the upper airways should be ensured as well as controlled ventilation, or assisted if necessary. The use of an opioid antagonist (naloxone) is recommended, despite its modest effect on the respiratory symptoms due to buprenorphine, the latter being strongly bound to the morphine receptors. Doxapram can also be used.
Postoperatively, one of the components of respiratory depression may be the residual effect of previously administered narcotics, so naloxone should be given as a first-line treatment, then the use of doxapram may be considered.
In the event of administration of an opioid antagonist (naloxone), the long duration of action of the product should be taken into account.
What should I do if I miss a dose?
Ask the prescribing doctor for his opinion.
What happens if you stop taking temgesic ?
Abrupt discontinuation of treatment may lead to the appearance of a withdrawal syndrome.
If you have further questions on the use of this medicine, ask your doctor or pharmacist for more information.
What is Forms and Composition ?
Appearance and shape
White tablet.
20 tablets in blister packs (Nylon / Aluminum / uPVC).
Other shapes
TEMGESIC 0.3 mg / ml, solution for injection, box of 2 ampoules of 1 ml
TEMGESIC 0.3 mg / ml, solution for injection, box of 10 ampoules of 1 ml
TEMGESIC 0.2 mg, sublingual tablet, box of 50
Composition
Active ingredient Sublingual tablet
Buprenorphine 0.2 mg * * per unit dose
Active ingredients: Buprenorphine
Excipients with known effects ? : Lactose
Other excipients:
Mannitol, Corn starch, Polyvidone excipient, Citric acid, Magnesium stearate, Sodium citrate
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/36qBWys via Edrug Online
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Calcium Sandoz Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Metabolism and nutrition Active ingredients: Calcium gluconolactate , Laboratory calcium carbonate
what is Calcium Sandoz ?
CALCIUM SANDOZ 500 mg, powder for oral solution in sachet-dose, box of 30 sachets-dose
what is Calcium Sandoz medication used for and indication?
This medicine contains calcium.
It is indicated :
In case of calcium deficiency following an increase in needs (growth, pregnancy, breastfeeding).
As an adjunct to bone decalcifications in the elderly, or after menopause, corticosteroid therapy, prolonged immobilization after resumption of mobility.
PRESENTATION (S) AVAILABLE FOR CALCIUM SANDOZ 500 MG
3 presentations are available for this drug:
10 sachet (s) of 4.2 g polyethylene aluminum foil
20 sachet (s) of 4.2 g polyethylene aluminum foil
30 sachet (s) of 4.2 g polyethylene aluminum foil
FEATURE DESCRIPTION Pharmaceutical class mineral supplements Active substance (s) for a 4.2 g sachet: calcium (carbonate) (0.150 g), calcium (gluconolactate) (3.405 g) General medicine no Pharmaceutical form powder for oral solution Route (s) of administration oral Social security reimbursement rate 65% Laboratory (s) SANDOZ Conditions of issue restricted prescription drug
Calcium Sandoz Dosage
1 to 2 sachets per day.
Calcium Sandoz Contraindications
Never take CALCIUM SANDOZ 500 mg powder for oral solution in sachet-dose in the following cases:
history of allergy to one of the constituents,
hypercalcaemia (abnormally high level of calcium in the blood),
hypercalciuria (exaggerated elimination of calcium in the urine),
Calcium lithiasis (kidney stones) – tissue calcifications,
prolonged immobilization accompanied by hypercalcemia and / or hypercalciuria: calcium should only be administered when mobility is restored,
due to the presence of aspartame, this drug is contraindicated in cases of phenylketonuria (hereditary disease due to an enzymatic deficiency)
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.
How To Take Calcium Sandoz ?
Administration mode
Oral route.
After opening the sachet, put the powder in a glass, add water and drink as soon as it dissolves.
how does Calcium Sandoz work?
Pharmacotherapeutic group: Mineral supplements, ATC codes: A12AA20.
Calcium ions are of decisive importance in the activation of biological systems. The threshold for stimulation of excitable membranes depends on the extracellular concentration of calcium ions.
Calcium ions further help regulate the permeability of cell membranes .
A deficiency of calcium ions in the plasma rises the excitability of neuromuscular , while a surplus of decreases .
Oral administration of calcium promotes bone remineralization in cases of calcium deficiency.
How To Store Calcium Sandoz ?
Keep this medication out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton after {EXP}. The expiration date refers to the last day of that month.
Store away from humidity.
Close carefully after each use.
Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
Calcium Sandoz Side Effects
Like all medicines, CALCIUM SANDOZ 500 mg powder for oral solution in a sachet-dose can cause side effects, although not everybody gets them.
Digestive disorders such as constipation, gas, nausea.
In case of prolonged treatment at high doses: risk of modification of the calcium level in the blood or urine.
extensive rash, hives and itching.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Calcium Sandoz Interactions
Thiazide diuretics decrease urinary calcium excretion. Due to an increased risk of hypercalcaemia, serum calcium should be monitored regularly during concomitant treatment with thiazide diuretics.
Systemic corticosteroids reduce the absorption of calcium. In case of concomitant use, it may be necessary to increase the dose of CALCIUM SANDOZ.
The digestive absorption of medicinal products containing tetracycline may be reduced in the event of concomitant administration of medicinal products containing calcium. Therefore, specialties containing tetracycline should be administered at least two hours before or four to six hours after oral intake of calcium.
The toxicity of cardiac glycosides may be increased by hypercalcemia resulting from calcium therapy. The patients must then be the subject of a clinical follow-up with control of the electrocardiogram (ECG) and the calcium level.
Due to a decrease in the gastrointestinal absorption of bisphosphonates or sodium fluoride, it is recommended, during concomitant treatments, to observe a delay of at least three hours before taking calcium.
Oxalic acid (found in spinach and rhubarb) and phytic acid (found in all cereals) can inhibit calcium absorption by forming insoluble complexes with calcium ions. After taking food with a high content of oxalic acid or phytic acid, the patient must wait two hours before taking products containing calcium.
Pediatric population
Interaction studies have only been performed in adults.
Not applicable.
Effects on ability to Drive and use machines
There is no known or expected effect on the ability to drive or use machines caused by taking CALCIUM SANDOZ.
Warnings and Precautions
Special warnings
Excessive calcium intake can be dangerous. DO NOT USE THIS MEDICINE WITHOUT MEDICAL ADVICE.
Precautions for use
Use this medication WITH CAUTION in case of prolonged treatment or renal failure: it is necessary to check the calcium level in the urine and in the blood.
This medication is likely to interact with certain foods rich in oxalic acid (spinach, rhubarb, sorrel, cocoa, tea, etc.) and phytic acid (whole grains, pulses, oil seeds, chocolate, etc.), which is why it is recommended to take it away from meals containing this type of food.
It is advisable to wait at least two hours between taking a drug based on bisphosphonates, cyclines or estramustine and taking CALCIUM SANDOZ 500 mg, powder for oral solution in sachet-dose.
IN CASE OF DOUBT, DO NOT HESITATE TO ASK FOR THE ADVICE OF YOUR DOCTOR OR YOUR PHARMACIST.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
For pregnant and breastfeeding women, the recommended daily intake of calcium (food intake and supplement) is 1,000 to 1,300 mg.
During pregnancy, the daily dose of calcium should not exceed 1500 mg.
Feeding with milk
Significant amounts of calcium are secreted in milk during breastfeeding, but it does not cause any side effects in the infant.
In case of calcium deficiency, CALCIUM SANDOZ can be administered during pregnancy and lactation.
What happens if I overdose from Calcium Sandoz ?
When taking an excessive dose of CALCIUM SANDOZ 500 mg powder for oral solution in sachet-dose, the following symptoms may appear:
Nausea, vomiting, thirst intense constipation.
If such effects occur, tell your doctor immediately who will take the necessary measures.
In case of prolonged overdose, calcifications may appear in the vessels or tissues.
What should I do if I miss a dose?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What happens if you stop taking Calcium Sandoz ?
Not applicable.
Not applicable.
Not applicable.
Not applicable.
What is Forms and Composition ?
Appearance and shape
Powder for oral solution in sachet-dose.
4.2 g in sachet (Aluminum-Polyethylene paper). Box of 30 sachets.
Other shapes
CALCIUM SANDOZ 500 mg, effervescent tablet, box of 1 tube of 20.
Composition
Active ingredient Powder for oral solution
Calcium gluconolactate 3,405 g *
Calcium carbonate 0.15 g *
* per unit dose
Active ingredients:
Calcium gluconolactate.
Calcium carbonate
Excipients with known effects ?
Aspartame
Other excipients:
Citric acid anhydrous
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
from Drug Online https://bit.ly/32tQjRo via Edrug Online
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Text
hiconcil Uses, Dosage, Side Effects, Precautions & Warnings
Generic drug of the Therapeutic class: Infectiology – Parasitology Active ingredients: Amoxicillin
HICONCIL 500 mg, capsule, box of 12 Medicinal product withdrawn from the market on 02/10/2008
what is hiconcil medication used for and indication?
They derive from the antibacterial activity and the pharmacokinetic characteristics of amoxicillin. They take into account both the clinical studies to which this drug has given rise and its place in the range of antibacterial products currently available.
They are restricted to infections susceptible to germs defined as:
ADULTS AND CHILDREN :
in initial treatment of :
acute pneumonia,
secondary infections of acute bronchitis, exacerbation of chronic bronchitis
ENT infections (otitis, sinusitis, angina) and stomatological
Urinary infections
male genital infections and gynecological infections,
digestive infections and bile,
Lyme disease: treatment of the primary phase (chronic erythema migrans) and the primary phase (chronic erythema migrans associated with general signs: asthenia, headache, fever, arthralgia, etc.).
as a relay treatment for the injectable route of endocarditis, septicemia.
as a prophylactic treatment for bacterial endocarditis.
IN ADULTS ONLY :
in combination with another antibiotic (clarithromycin or imidazole) and an antisecretory, eradication of Helicobacter pylori in cases of peptic ulcer disease in adults (after endoscopic evidence of the lesion and infection).
Consideration should be given to official recommendations regarding the appropriate use of antibacterials.
hiconcil Dosage
One measuring spoon (5 ml) contains 125 mg of amoxicillin.
For adults and in certain cases in children (large doses, older children), other presentations of amoxicillin are more suitable.
Dosage of oral amoxicillin
IN SUBJECT WITH NORMAL RENAL FUNCTION :
ADULTS :
The usual dosage of amoxicillin is 1-1.5 or 2 g / day in 2 to 3 doses.
Special cases :
angina : 500 mg every 12 hours, for 10 days.
In acute strep throat, a 6-day treatment at a dose of 2 g / day in 2 doses ensures eradication of the streptococcus.
acute pneumonia: 3 g / day, or 1 g every 8 hours.
Lyme disease :
chronic migrant strictly isolated erythema: 4 g / 24 hours
in the event of systemic manifestations suggesting a hematogenous dissemination of Borrelia burgdorferi , the doses may be increased up to 6 g / 24 h.
The duration of treatment will be 15 to 21 days.
endocarditis and septicemia (relay of the injectable route) : the dosage can be increased up to 6 g per 24 hours in at least three doses.
prophylaxis of bacterial endocarditis :
oral protocol: 3 g as a single dose, administered within one hour of the risky procedure,
relay of the parenteral protocol: 1 g per os 6 hours after parenteral administration.
Helicobacter pylori eradication in case of peptic ulcer disease in adults , the following regimens are recommended
amoxicillin 1 g morning and evening, combined with clarithromycin 500 mg morning and evening and omeprazole 20 mg morning and evening for 7 days, then 20 mg omeprazole daily for 3 additional weeks in case of active duodenal ulcer or 3 to 5 weeks additional in case of progressive gastric ulcer,
or
amoxicillin 1 g morning and evening, combined with clarithromycin 500 mg morning and evening and lansoprazole 30 mg morning and evening, for 7 days, then 30 mg of lansoprazole per day for 3 additional weeks in case of active duodenal ulcer or 3 to 5 weeks additional in case of progressive gastric ulcer.
The effectiveness of the treatment depends on compliance with the dosage regimen, in particular on taking the triple therapy during the first 7 days.
CHILD :
The usual dose is as follows:
for children under 30 months : 50 mg / kg / day to 100 mg / kg / day in 3 doses at 8 hours
or children over 30 months: 25 to 50 mg / kg / day in 2 or better 3 doses without exceeding the dosage of 3 g / day.
For more severe infections, as well as for endocarditis and septicemia (relaying the injection route): the dosage can be increased up to 150 mg / kg / day in 3 or 4 doses, without exceeding the dosage of 6 g /day.
Special cases :
Lyme Disease :
Chronic erythema migrant strictly isolated: 50 mg / kg / 24 h
in the event of systemic manifestations suggesting a hematogenous dissemination of Borrelia burgdorferi , the doses may be increased up to 6 g / 24 h.
The duration of treatment will be 15 to 21 days.
prophylaxis of bacterial endocarditis:
Oral protocol: 75 mg / kg single dose, administered in the hour before the gesture at risk
relay of the parenteral protocol: 25 mg / kg per os 6 hours after parenteral administration.
angina : in acute strep throat in the over 30 month old child, a 6-day treatment at a dose of 50 mg / kg / day in 2 divided doses ensures the eradication of streptococci.
IN THE SUBJECT WITH RENAL INSUFFICIENCY :
Administer a first loading dose (Do) equivalent to the normally prescribed dose then, depending on the degree of severity of the pathology:
Creatinine clearance: Dosage schedule .
greater than 30 ml / min: no adaptation: continue treatment with the usual dose and the recommended frequency.
from 10 to 30 ml / min: Do / 2, every 12 hours.
less than 10 ml / min: Do / 2, every 24 hours.
Hemodialysis: Do, then Do / 2 per day. On dialysis days, administer Do / 2 after the dialysis session.
Method of administration :
ORAL.
This medicine can be taken with or between meals.
Use the measuring spoon supplied with the bottle.
hiconcil Contraindications
Penicillin allergy
Cephalosporin allergy
Child under 6
Congenital galactosemia
Glucose malabsorption syndrome
Galactose malabsorption syndrome
Lactase deficiency
CONTRA-INDICATED:
This medication MUST NEVER BE USED in case of allergy to antibiotics of the beta-lactam family (penicillins and cephalosporins) or to one of the other constituents.
The capsule intake is contraindicated in children under 6 years of age, because it can lead to a wrong route.
Due to the presence of lactose, this drug is contraindicated in cases of congenital galactosemia, glucose and galactose malabsorption syndrome or lactase deficiency.
ADVISED AGAINST:
This medication SHOULD NOT GENERALLY BE USED in combination with methotrexate (see interactions).
how does hiconcil work?
ABSORPTION : When
taken orally, amoxicillin is approximately 80 percent absorbed.
This absorption is not influenced by food.
DISTRIBUTION :
The serum peak, 2 hours after the intake, reaches a level of 7 to 10 µg / ml for an intake of 500 mg and of 13 to 15 µg / mI for an intake of 1 g.
Serum levels increase with dose.
In subjects with normal renal functions, the half-life is 1 hour on average.
Diffusion in most tissues and biological environments: presence of antibiotics at therapeutic rates observed in bronchial secretions, sinuses, amniotic fluid, saliva, aqueous humor, CSF, serous membranes, middle ear.
Amoxicillin has a good diffusion in the tonsils, depending on the serum concentrations: between 1.5 and 3 hours after taking 1 gram of amoxicillin in adults, the tonsil concentrations are on average 3 to 4 µg / g .
Amoxicillin crosses the placental barrier and passes into breast milk.
Protein binding rate: 17%.
BIOTRANSFORMATION :
Amoxicillin is partly transformed in the body into the corresponding penicilloic acid. About 20 percent of the dose given in this form is found in the urine.
EXCRETION :
The absorbed part is excreted in active form:
mostly in the urine (in about 6 hours, 70 to 80 percent of the absorbed dose),
in the bile (5 to 10 percent).
hiconcil Side Effects
The classification of undesirable effects used is as follows :
very common:> = 1/10.
common:> = 1/100; <1/10.
uncommon:> = 1/1000; <1/100.
rare:> = 1/10000; <1/1000.
very rare: <1/10000.
not known: frequency cannot be estimated from the available data.
Blood and lymphatic system disorders :
Very rare: reversible leukopenia, neutropenia, agranulocytosis, thrombocytopenia and hemolytic anemia.
Not known: eosinophilia.
Nervous system :
Very rare: convulsions.
Not known: dizziness, headache.
Gastrointestinal disorders :
Common: diarrhea, nausea.
Uncommon: vomiting.
Very rare: pseudomembranous colitis, hemorrhagic colitis.
Not known: superficial tooth staining in children, usually reversible after brushing teeth.
Kidney and urinary tract disorders :
Not known: acute interstitial nephritis and crystalluria.
Skin and subcutaneous tissue disorders :
Common: rash.
Uncommon: urticaria and pruritus.
Very rare: erythema multiforme, Stevens-Johnson syndrome, Lyell syndrome, bullous or exfoliative dermatitis. These skin manifestations may be more frequent and / or more intense in patients with infectious mononucleosis or active lymphoid leukemia. Acute generalized exanthematous pustulosis (see warnings and precautions for use).
Infections and infestations :
Frequent: mucocutaneous candidiasis.
mmune system :
Very rare: anaphylaxis (including anaphylactic shock), serum sickness and hypersensitivity vasculitis (see warnings and precautions for use).
Not known: allergic manifestations, including urticaria, angioedema, respiratory discomfort.
Hepatobiliary disorders :
Very rare: hepatitis, cholestatic jaundice.
Frequency not known: moderate and transient increase in serum transaminases (ALT and / or ASAT).
hiconcil Interactions
RECOMMENDED ASSOCIATION :Methotrexate:
Increase in the effects and hematological toxicity of methotrexate by inhibition of renal tubular secretion by penicillins.
COMBINATION TO BE TAKEN INTO ACCOUNT :
Allopurinol:
Increased risk of skin reactions.
SPECIAL PROBLEMS OF INR IMBALANCE :
Many cases of increased activity of oral anticoagulants have been reported in patients receiving antibiotics. The marked infectious or inflammatory context, the age and general condition of the patient appear to be risk factors. Under these circumstances, it appears difficult to distinguish between the infectious pathology and its treatment in the occurrence of the INR imbalance. However, certain classes of antibiotics are more involved: these include fluoroquinolones, macrolides, cyclins, cotrimoxazole and certain cephalosporins.
Not applicable.
Warnings and Precautions
The occurrence of any allergic manifestation requires the discontinuation of treatment, and the establishment of an appropriate treatment.
Severe and sometimes fatal hypersensitivity reactions (anaphylaxis) have been observed exceptionally in patients treated with beta-lactams.
Their administration therefore requires an examination.
Given a history of typical allergy to these products, the contraindication is definite.
The penicillin allergy is crossed with the cephalosporin allergy in 5 to 10% of cases. This leads to the proscription of penicillins when the subject is known to be allergic to cephalosporins.
In the event of renal insufficiency, adjust the dosage according to the creatinine clearance or the creatinine level (see dosage and method of administration).
In the event of administration of high doses of amoxicillin, sufficient fluid intake should be ensured to reduce the risk of crystalluria.
A positive direct Coombs test was obtained during treatment with beta-lactams. This could also occur in subjects treated with amoxicillin.
At very high concentrations, tends to amoxicillin:
reduce assay results in blood glucose
interfere in the determinations of the total protein level of the serum by color reaction,
give a false positive color reaction in glycosuria assays by the semi-quantitative colorimetric method.
Treatment of Lyme disease: Jarisch-Herxheimer reactions may occur.
This medicinal product contains 5.7 mg of sodium per measuring spoon: take this into account only in children on a strict sodium diet.
Due to the presence of sucrose , this medication is contraindicated in cases of fructose intolerance, glucose and galactose malabsorption syndrome or sucrase-isomaltase deficiency.
This medicine contains 2.2 g of sucrose per measuring spoon: take this into account in the daily ration.
Breast-feeding: there is little passage into breast milk and the quantities ingested are much lower than the therapeutic doses. As a result, breast-feeding is possible while taking this antibiotic. However, discontinue breast-feeding (or medication) if diarrhea, candidiasis, or rash occurs in the infant.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
Studies in animals have not produced any evidence of teratogenic effects. In the absence of a teratogenic effect in animals, a malformative effect in humans is not expected. Indeed, to date, the substances responsible for malformations in the human species have been shown to be teratogenic in animals during well-conducted studies on two species.
Clinically, analysis of a high number of exposed pregnancies apparently revealed no specific malformative or foetotoxic effects of amoxicillin. However, only epidemiological studies would make it possible to verify the absence of risk.
Therefore, amoxicillin can be prescribed during pregnancy if needed.
The passage of amoxicillin in breast milk is low and the amounts ingested are much lower than the therapeutic doses. As a result, breast-feeding is possible while taking this antibiotic.
However, stop breast-feeding (or the medication) if diarrhea, candidiasis or rash occurs in the infant.
What happens if I overdose from hiconcil ?
The manifestations of overdose can be neuropsychic, renal (crystalluria – see warnings and precautions for use) and gastrointestinal.
Treatment is symptomatic, particularly monitoring the fluid and electrolyte balance.
Amoxicillin can be removed by hemodialysis.
What is Forms and Composition ?
Appearance and shape
White and orange capsule.
12 capsules in blister packs (PVC / Aluminum).
Other shapes
HICONCIL 125 mg / 5 ml, powder for oral suspension, 60 ml vial of reconstituted suspension
HICONCIL 250 mg / 5 ml, powder for oral suspension, 60 ml vial of reconstituted suspension
HICONCIL 500 mg / 5 ml, powder for oral suspension, 60 ml vial of reconstituted suspension
Composition
Active ingredient Capsule Amoxicillin 500 mg *
* per unit dose
Active ingredients: Amoxicillin
Excipients with known effects ? : Lactose monohydrate
Other excipients: Magnesium stearate, Colloidal anhydrous silica, Head: Gelatin, Erythrosine, Iron oxide yellow, Titanium dioxide, Body: Gelatin, Titanium dioxide
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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