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Ginkgo Biloba
Ginkgo Biloba is one of the world’s oldest natural medicines and it is gaining a new reputation as an efficient natural nootropic. Ginkgo Biloba is a medicinal plant from traditional Chinese medicine that is commonly called Maidenhair tree“. It was used to increase energy and treat various conditions ranging from infection to asthma.
Today, Ginkgo Biloba is one of the top 10 most popular supplements in the west. In the traditional Chinese medicine seeds and fruit were first used, they more recently included leaf extract. The leaves of the Ginkgo tree have been used to create medical treatment for many physical ailments, including hearing problems, headaches, eye issues, bronchitis, asthma and many other conditions.
Modern studies have proven that Ginkgo Biloba increases circulation and it is being studied as a potential treatment for various conditions associated with impaired blood flow, including sexual dysfunction and headaches. It is thought to have some benefits in fighting the memory disorders associated with Alzheimer’s disease. It is also known to decrease leg cramping and pain caused by training. Ginkgo has also been proven to benefit individuals who suffer Reynaud’s Syndrome, which is a painful response to cold, particularly in the toes and fingers.
However, some of the Ginkgo Biloba’s most interesting benefits are associated with cognition, mood and memory. By enhancing blood flow and promoting circulation in the brain, Ginkgo Biloba works as a nootropic. People who use it claim it increases learning, boosts mood and promotes memory. Ginkgo is also known to work as an antioxidant, protecting the brain from free radicals and from oxidative stress.
Ginkgo Biloba is a popular addition to nootropic stack because it interacts well with other supplements and may work as a potentiator for other nootropics.
What was one thought of a folk medicine elixir is a proven memory enhancer with many other cognitive benefits, including combating Alzheimer’s disease.
Benefits
Energy booster – Ginkgo Biloba has been regarded a potent energy enhancer for many centuries. Modern studies indicate that the ancient Chinese physicians who used it as a general tonic were certainly on the right path. By promoting circulations throughout the body, Ginkgo increases oxygenation and the absorption of nutritients, enhancing endurance and making muscles perform longer and work better.
Reduce leg cramping and pain – Ginkgo Biloba has been proven to reduce training-related leg cramping and pain. Ginkgo Biloba’s circulatory properties help alleviate this problem, which is caused by insufficient blood flow. The same circulatory properties also enable Ginkgo to soothe the discomfort of Raynaud’s syndrome, a disorder in which cold temperatures induce painful vasospasms of the toes and fingers.
Mood enhancement – Ginkgo Biloba has a longstanding reputation as a memory booster and recent studies are showing that reputation to be well-earned. Many clinical studies and researches have proven that Ginkgo Biloba supplements noticeably promoted memory in individuals suffering from mild to moderate primary degenerative dementia. Although similar researches on healthy volunteers have been less conclusive, many people who use Ginkgo say that using this supplement makes their memory quicker, clearer and sharper.
Improved cognition – Ginkgo’s ability to promote circulation and blood flow in the brain makes it an effective and potent nootropic, both on its own and in combination with other nootropics. Improved cerebral blood flow results in promoted absorption of nutrients and oxygen, which in turn produces a feeling of mental alertness and clarity. It is also known to modulate the release of many crucial neurotransmitters, such as Acetylcholine, the neurotransmitter most closely connected with studying.
Improved vision – Clinical trials have proven that Ginkgo promotes vision in individuals who suffer from glaucoma. It has also been shown to benefit individuals who suffer from macular degeneration, an incurable age-connected disease in which the central part of the retina deteriorates.
Mood management – Ginkgo has been used for hundreds of years as a mood booster, and clinical trials on volunteers suffering from anxiety disorder proves that it is an efficient treatment for anxiety. Ginkgo has also been proven to be efficient mood modulator among healthy adults, and there are scientific proofs supporting its benefits for individuals suffering from depression.
How It Works
The main active components found in Ginkgo Biloba’s leaves are bilobalides, ginkgolides and flavonoids. The actions of these components make Ginkgo Biloba an antioxidant and anti-inflammatory that also decreases platelet accumulation, increases cerebral glucose utilization, affects the vasomotor system and regulates neurotransmitter release.
It is believed that the main source of Ginkgo Biloba’s power lies in its ability to enhance circulation. This supplement improves and regulates tone in the vascular system by managing thromboxane A2 and prostacyclin.
Increased circulation then creates outstanding conditions in all vital organs, particularly the brain. Maintaining a healthy blood flow to the brain is best way to enhance concentration and increase memory. It also has potential to heal migraines and headaches.
The management of blood clotting is another one of Ginkgo Biloba’s main circulatory mechanisms. Through ginkgolide B, redundant blood clotting is hampered. This can prevent many cerebrovascular problems, including thrombus and myocardial ischemia.
Enhanced circulation plays an important role in Ginkgo’s nootropic and therapeutic capabilities. Improved blood flow throughout the body decreases circulation-related cramping and pain and makes muscle work better. Increased cerebral circulation makes the brain works more effectively, absorbing nutrients and oxygen quicker and more thoroughly.
Ginkgo Biloba is also natural monoamine oxidase (MAO) inhibitor. This function is a crucial regulator of mental confidence and good mood. It prevents loss of key energy and mood hormones like norepinephrine, serotonin and dopamine. Also, Ginkgo’s cyanogenic glycosides attack harmful fungus and bacteria throughout the body.
Ginkgo Dosage
Although Ginkgo Biloba has been used since at least 2500 BC, the Food and Drug Administration (FDA) has still not held a formal Ginkgo review. As a result, there is no official recommended dosage.
However, Ginkgo dosages of up to 360 mg in one day (split into 3 dosages) have been tested and found to be both efficient and safe.
If used as a daily supplement for the prevention of cognitive decline and for overall brain health, taking 40 to 120 mg dosages one to three times a day is usually recommended. For a fast mental boost of mental performance, a single dosage of 120 mg a few hours before the task should be a nice starting point.
The daily total amount of Ginkgo can be taken all at once or spread over 2 to 3 dosages. Ginkgo Biloba should usually be taken with food.
Ginkgo Side Effects
As shown by its many centuries of use as a folk medicine, Ginkgo Biloba is mostly without severe side effects for most individuals. Some minor side effects including gas, heart palpitations, headaches and nausea may happen in some cases, but it is not the norm. These side effects are rare and are generally temporary. However, you it is recommended to reduce a dose if you experience them.
Ginkgo supplements are derived from the leaves of ginkgo tree. However, consuming extracts made from the ginkgo seeds or eating the seeds of the ginkgo tree can cause dangerous seizures.
People who are using antidepressants, anticoagulants or anticonvulsants or who have just had surgery are recommended to avoid using Ginkgo Biloba. Also, small children, women who are expecting a baby or breastfeeding are recommended to avoid this supplement.
Stacking
Ginkgo is a popular natural nootropic which works very well on its own but truly shines when combined with other supplements. Ginkgo is often referred to as the „neutral nootropic“ and some people who take Ginkgo claim its cognition increasing effects are best achieved when it is stacked or combined with other supplements.
Ginkgo, Gotu Kola and Ashwagandha
Gotu Kola is a reputable natural supplement known primarily for boosting energy, and it also promotes conditions of chronic venous insufficiency and positively effects cardiovascular health. Ashwagandha is an ancient herbal nootropic which dates back to Ayuervedic medicine. It is known mainly for its potent anti-anxiety effects, but it also increases cognition and mood.
Ginkgo and Vinpocetine Stack
Vinpocetine is a natural nootropic and it is best known as a memory increaser. Like Ginkgo, Vinpocetine has been proven to work as a brain protectant and to promote blood circulation.
Brands
When shopping around for Ginkgo Biloba, make sure that you look out for the following brands, because these are regarded to be the top 5 Ginkgo supplements available in the market today.
Now Foods Ginkgo Biloba
Cardiovascular Research Ginkgo Biloba
Jarrow Formulas Ginkgo Biloba
Natrol Ginkgo Biloba
Advanced Ginkgo Smart
Where to Buy
Ginkgo is one of the most widely available supplements. It is both available in storefronts and can also be purchased online. Ginkgo is available in both capsule and powder form. It is recommended to buy Gingo in bulk powder form from PowderCity.com if you want to use Ginkgo over the long-term and would like a more inexpensive option.
Ginkgo Biloba is used as both a general tonic and a specific treatment for many centuries. It is currently being tested as a potential treatment for many memory-related and circulatory disorders. Ginkgo can promote cognition and memory, increase energy, and work as a strong potentiator in combination with other supplements. Ginkgo is affordable, very well-tolerated, safe and readily available everywhere.
Ginkgo is a supplement that’s well worth a try if you want to make the most of your body and brain. Read more interesting articles here.
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Bromantane Review – Stimulant and Anxiolytic at the Same Time
Bromantane Review
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Bromantane (brand name Ladasten) was originally developed as an immuno-stimulant drug in the laboratories and pharmaceutical companies of Russia. Soldiers and sportsmen in Russia have been using Bromantine since the late 1980’s. It is adamantane derivative and was originally developed to stimulate the immune system.
Product Description:
Bromantane is a stimulant and an anxiolytic at the same time. These two effects usually negate the effects of each other so the fact that Bromatane acts as a mental relaxant and a stimulant makes this drug unique.
Bromantane was also used to reduce recovery times after strong physical exertion. Although this drug soon fell out of use by the army, it still continued to be researched in areas such as sports medicine, because it was found to increase athletic performance. Bromantane is said to act really fast to increase motivation, alertness and overall mental energy.
This nootropic has also been proven to provide athletes with performance improvements. However, in 1996 this drug was listed in the IOC list of banned substances shortly upon learning that it is being used by several athletes to gain advantage over other athletes in the year’s Olympic Games.
This nootropic supplement is regarded to be a new nootropic with psychostimulatory effects. It is also regarded to be actoprotector. This means that they are synthetic adaptogens with a remarkable magnitude that can enhance physical performance.
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General thoughts:
Benefits
This nootropic supplement is usually used in Russia as a treatment for neurasthenia. This medical condition is marked by depressed mood, anxiety, irritability and fatigue.
The very beneficial side effect profile of this nootropic is one contributing to factor to its improvement in popularity as a potential substance. Bromantane is one of the few stimulating drugs which can be said to fit this definition because „true“ nootropic drugs do not carry any addictive potential.
This nootropic would theoretically decrease any fatigue that comes alongside long periods of mental exertion because of its effects as an actoprotector. This feature makes Bromantane a possible study help. This effect would be improved by Bromantane’s stimulating effect, which leads to improved concentration and motivation. However, this nootropic has not yet seen any official testing regarding its exact effects on cognition and cognitive health.
There are a variety of benefits that Bromantane can provide. This includes, but is not limited to some of the following:
Exhibit anxiolytic effects
Increases mental and physical endurance under stress
Enhances amounts of dopamine and serotonin neurotransmitter in the brain
Stimulation of the nervous system
Helps with liver detoxification
Decreases anxiety
Shown to help boost mood and motivation
Improves cognition and learning capability
Low to no potential for addiction
Boosts the immune system
Low toxicity
Stimulates euphoria
Enhances muscle mass and strength
Decreases overheating
Very few side-effects
Helps protect against hyperthermia
How It Works
Bromantane is known to exhibit qualities of both adaptogens and stimulants. However, the exact methods of action of this nootropic are not as well researched as other nootropic substances.
This nootropic works mainly by inhibiting the reuptake of both serotonin and dopamine in the brain. Although the method of action is not that well understood, experimentation has indicated that the administration of Bromantane induces a release of dopamine.
Additionally, this nootropic also triggers a notable increase in the 5-HT and 5-HIAA content in the frontal cortex of the brain. It also delays an increase in their content in subcortial brain regions, therefore a stable reduction in the 5-HT and 5-HIAA in the cerebellum is noticed.
This increase activates the part of the brain that is responsible for short-term memory task, motivation, attention and reward.
Bromantane stimulates synthesis of cytochrome P-450, strengthens GABA-ergic mediation reducing gene expression and acts as an anxiolytic.
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Bromantane Dosage
A typical single dosage of Bromantane can range from 50 to 100 mg. However, Bromantane dose seems to be sex-dependent.
Females absorb this drug much faster than males. That’s why this nootropic has a much shorter half-life in females than in males.
Time to achievement of this nootropic is 4 hours in males and 2.75 hours in females. Bromantane is highly lipophilic and it is quickly absorbed by the gastrointestinal tract into the blood when taken orally.
The effective dosage for this nootropic supplement is 30 mg/kg in mice because Bromantane has a stimulant effect at this dosage.
In animal researches, toxicity was reached only at very high levels of administration (600 mg/kg in mice). This nootropic has a tranquilizing effect at toxic dosages.
Stacking
Bromantane can be taken on its own but also does very well in nootropic stacks for synergistic benefits.
Bromantane, Kava Kava, AcetylCarnitine, Agmatine and Fish Oil Stack
Stacking Bromantane with Kava Kava,, AcetylCarnitine, Agmatine and Fish Oil would be a potent stack which would decrease anxiety, improve health, stimulation and motivation.
Bromantane, Clomipramine, Citalopram, Liothyronine (T3) and Agomelatine Stack
This is a very powerful stack that would to get you out of bed and not have to worry about falling asleep before noon.
Brands
If you would like to purchase Bromantane, here are the top brands:
Anonymous Pharm
Ladasten
Nootropica Bromantane Powder
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Side Effects:
There are no established side effects in the scientific literature surrounding this nootropic supplement. Bromantane has not demonstrated addictive potential, unlike most stimulant drugs and after prolonged periods of use it does not seem to build a tolerance.
One research suggests that high dosages of this supplement in rats can cause enhancement in the DNA-binding activity of the beta-amyloid precursor protein (β-APP) gene promoter.
This can be linked to the pathogenesis of Alzheimer’s disease. However, it is important to note that the dosages used in this research are around 68 times the normal prescription dosage of this nootropic.
Also, many users say that they wouldn’t recommend Bromantane for daily use because it made them feel light headed and out of it for some time.
Conclusion:
Bromantane is available in both capsule and powder form. It is recommended to buy it in powder form because it may be cheaper. You can order Bromantane powder at Ceretropic.com or Nootropica.pw. If you want to purchase the original Russian brand Ladasten, you can order it at AwakeBrain.com.
Bromantane is a nootropic supplement that provides the potential of numerous cognitive benefits. This nootropic works as a stimulant and anxiolytic simultaneously and for this reason it is considered to be a unique drug.
Bromantane also serves to boost performance by improving the body’s resistance to physical and mental fatigue and exhaustion. Unfortunately, this nootropic lacks the wide spectrum of study. However, it appears that there is relatively no risk for addiction when taking this drug.
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Bromantane Review – Stimulant and Anxiolytic at the Same Time
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Bromantane Review Focus Energy Mood Cognition PROS · Reduces anxiety · Promotes cognitive health · Calms stress · Supports a relaxed mood · Regulates the body · Improves long-term well-being · Enhances calmness and happiness CONS - The door gets hot when in use - Not...
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The post Bromantane Review – Stimulant and Anxiolytic at the Same Time appeared first on It Made My Day.
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Vinpocetine Review
Vinpocetine Review
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Vinpocetine is an extract from the seeds of the Vince Minor plant. It is a unique supplement which boosts cognition, mood and memory in many ways.
It increases the production of vital neurotransmitters, it enhances the absorption of nutrients and oxygen, it promotes cerebral blood circulation and flow, and it works as an antioxidant, protecting the brain from the aging process, negative effects of stress and environmental toxins.
Many people consider Vinpocetine to be one of the best nootropics that should be used by everyone on a regular basis. You can buy Vinpocetine in its own for use in a stack or you can find it in nootropic products, such as Alpha Brain.
Product Description:
Vinpocetine used today is synthetically produced to ensure quality. However, the herbal origins of this compound mean that it is generally classified as a natural nootropic. Vinpocetine was first isolated in 1975 in Hungary.
It has been mass produced in Hungary as a prescription medicine since 1978. It is used throughout Eastern Europe as a drug for age-related memory deterioration and cerebrovascular disorders. In the US it is available as a dietary supplement because it is not regulated as a pharmaceutical.
Although clinical trials of this supplement have been limited, it has shown to be an efficient vasodilator with specific and directs effects on the brain.
It has also been proven to increase cerebral metabolism, and these factors are the basis of Vinpocetine’s nootropic abilities. It has also been proven to be a powerful anti-inflammatory agent and it is thought to have potential as a treatment for Parkinson’s disease, Alzheimer’s disease, and other age-related neurodegenerative disorders.
Vinpocetine is both safe and well tolerated. It works effectively both in combination with other supplements and on its own.
Although at present Vinpocetine is less well-known than many other brain drugs, it has enormous potential for both cognitive and anti-aging improvement.
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General thoughts:
Benefits
Vinpocetine’s actions as an anti-inflammatory agent and vasodilator make it a potent and efficient nootropic, increasing cognition by enhancing the effectiveness of the brain and promoting the overall health.
Mood improvement: Researches indicate that Vinpocetine stimulates enhanced production of many vital neurotransmitters, the brain chemicals which enable the transfer of nerve impulses. Making more of these chemicals available for use in the brain not only increases cognitive abilities and learning, but can also decrease anxiety, enhance a feeling of energized well-being and boosts cognitive abilities and learning.
Improved mental clarity and quicker learning: Vinpocetine is also thought to enhance the body’s ability to convert dietary lipids and glucose to ATP (adenosine triphosphate), the cellular coenzyme which transfers chemical energy for metabolism. The more adenosine triphosphate available for use in the brain, the quicker learning and the improved intellectual capacity can take place. The presence of ample ATP in the brain increases feelings of mental clarity and decreases feelings of „brain fog“ (mental fatigue).
Improved concentration and focus: Vinpocetine has been proven to work as a limited-action vasodilator, boosting blood circulation and flow in the brain without effecting blood pressure in the rest of the body. Boosted blood circulation and flow promotes the overall health and effectiveness of the brain, which in turn lengthens attention span and improves concentration and focus.
Memory enhancement: Vinpocetine is prescribed throughout Eastern Europe as a treatment for memory disorders. It is widely recognized for its ability to sharpen memory. Most of clinical trials indicate that this supplement can enhance memory formation in older individuals with memory deterioration. Also, people who use Vinpocetine claim that it helps them recall learned information more accurately and quickly.
How It Works
Vinpocetine is not completely water soluble and is usually incompletely absorbed. However, concentrations peak quickly in the blood and get into central nervous system and brain with relative rapidity.
Initial scientific researches suggest that Vinpocetine has many effects on the brain. The most important of these effects is the increasing oxygen utilization and blood circulation.
Vinpocetine enhances blood flow in the brain without effecting blood pressure or circulation throughout the rest of the body. Vinpocetine has also been proven to specifically aim the areas of poor circulation within the brain and damaged brain cells.
The enhanced flow of blood and associated oxygenation makes the brain more tolerant to hypoxia and ischemia, conditions of insufficient and decreased oxygen associated with stroke and other brain injuries and pathologies.
In healthy brains and enhanced flow of blood and associated oxygenation is thought to have important nootropic properties.
Also, enhanced oxygenation and circulation in the brain improves overall brain function with enhanced production of coenzyme ATP, which is vital for cerebral metabolism.
By producing a sufficiency of coenzyme ATP Vinpocetine enhances the effective usage of glucose and other brain nutrients and thus promotes mental clarity.
Vinpocetine also works as an anti-inflammatory agent in the brain. It decreases the expression of the vascular and proinflammatory cell adhesion molecules which can cause neuronal death in states such as Parkinson’s and Alzheimer’s disease.
The anti-inflammatory characteristics of Vinpocetine make it a promising neuroprotectant which could potentially have major anti-aging benefits.
This supplement has also been proven to interact with potassium, calcium and sodium ion channels in the brain, modulating the release of different neurotransmitters like dopamine, serotonin, noradrenalin and acetylcholine. By enhancing the availability of these neurotransmitters Vinpocetine not only effects overall cognition and memory but it may boost mood by increasing feelings of well-being and energy and soothing feelings of anxiety.
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Dosage
The recommended dose for Vinpocetine is 50 to 100 mg, divided into two or three daily dosages. You may experience positive results with even smaller dosages, particularly when used in a stack with other nootropic supplements.
It is recommended to begin by taking 10 mg of Vinpocetine and do not enhance until you have minimum 7 days of side-effect free experience.
Stacking
Vinpocetine can be efficient nootropic taken on its own, but it is known to work extremely well when paired with other nootropics and is often found in preformulated supplements. Here are some ideas if you like to make your own nootropic stack
Racetam and Vinpocetine Stack
This nootropic stack will make the most of intensive learning time. The Vinpocetine will work with the Aniracetam to enhance memory, the Piracetam will boost general cognition and the Alpha GPC will ensure sufficient top-quality choline for transformation to Acetylcholine, also known as the „studying neurotransmitter.“
Ginkgo Biloba and Vinpocetine Stack
Ginkgo Biloba and Vinpocetine act as potentiators for each other, with the combination of enhancing efficiency and overall potency of both. This amazing stack will boost productivity and motivation, promote mood and increase cognitive abilities.
Brands
Vinpocetine is available with the brand names of Cavinton, Cognitol, Intelectol and Neurovin. Most users prefer to purchase Vinpocetine as a part of the popular nootropic supplement Alpha Brain.
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Side Effects:
When used as recommended, Vinpocetine is regarded safe with low risk of side effects. It is usually well tolerated and has a lower toxicity rating than caffeine.
Although there are no severe Vinpocetine side effects, some individuals may encounter mild discomfort when using this supplement. In some instances difficulty falling asleep, anxiety, nausea, light-headedness, stomach pain and headaches were reported.
Vinpocetine has anti-platelet effect, which means that it may affect platelet accumulation and blood clotting. For this reason, using Vinpocetine with anticoagulant supplements or drugs could result in negative interactions.
This supplement is contraindicated for individuals undergoing planned surgery within 14 days, individuals with bleeding disorders and immunocompromised individuals. There are not enough proofs to determine safety for children, women who are expecting a baby or women who are nursing.
It is recommended to drink lots of water when taking Vinpocetine. You should not use it too late in the days because it may cause insomnia. You should consult your doctor before taking Vinpocetine to determine the right way to use it and whether it is appropriate for you.
Conclusion:
Fortunately, Vinpocetine is quite easy to buy and conveniently can be purchased online. Amazon can be purchased from Amazon by companies Absorb health and Life Extension. Vinpocetine can also be bought more economically in powder form from PowderCity.com. This is the best source for bulk nootropics.
Vinpocetine’s unique mechanisms of action, promise as a brain protectant and potent cognitive improvement capabilities are sparking interest of all nootropic users. Vinpocetine is dependable brain increaser on its own and works well with other nootropics, making it perfect addition to most nootropic stacks. This supplement is ready available, inexpensive and safe.
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Sunifiram – Nootropic 1000 Times Stronger than Piracetam
Sunifiram Review
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Sunifiram, also known as DM-235, is an exciting new development in the world of nootropics. It is a derivative of the Racetams. It provides a very potent cognitive enhancement along with energy and mood improvement. Having been synthesized in the early 2000s, Sunifiram is one of the most recent supplements to be introduced into the nootropic line of supplements. Sunifiram is discovered recently and only a limited body of research is available to date, but preliminary animal researches indicate that it is a very efficient nootropic shown to improve memory and learning. It is believed to have amazing potential as a possible treatment for many neurological disorders, including amnesia, Parkinson’s disease, Alzheimer’s disease.
Product Description:
Some studies have suggested that it works similarly to Piracetam but it is over 1000 times more powerful than Piracetam for the same dose.
No severe side effects have been documented. There have been no documented clinical trials or researches involving humans but animal researches suggest that Sunifiram is both well tolerated and safe. Also, it may be even less toxic than the Racetams.
Sunifiram is a derivative of the Racetam group of nootropics. However, it has a different chemical structure and it is classified as a piperazine alkaloid rather than Racetam. Sunifiram is also considered an Ampakine because it is an AMPA agonist.
Sunifiram is extremely efficient at increasing memory function as well as alertness, decision making, learning and attention span.
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General thoughts:
Benefits
Depression and anxiety management: Although animal researches don’t show that Sunifiram works as an anxiety and anti-depressant reliever, some people who take it claim that it has these effects. This could be because of the compound which interacts with the glutamatergic AMPA receptors and works as a mild stimulant or its actions as an Ampakine.
Perceptual/visual booster: While reports of perceptual and visual enhancement are far from universal, many users report that using Sunifiram gives them a brighter look, making colors more vibrant and shadow and light more pronounced. For some users it also makes music more emotionally meaningful and mentally engaging.
Memory and learning: Sunifiram has been shown to work as a potent nootropic, providing measurable improvements in memory recall, retention and learning speed. Animal researches proved that this supplement not only increased performance in learning tasks, it actually reversed chemically-induced amnesia.
Enhanced sex drive: A significant percentage of people who take Sunifiram claim that it has noticeable and distinct aphrodisiac properties, enhancing their sex drive. This effect has not been proven in animal researches and doesn’t appear to be universal.
Energy and mood booster: Many people who take Sunifiram claim that it gives them more energy and a brighter, happier outlook.
Enhanced motivation and focus: People who use Sunifiram often report that it improves their concentration and focus and enhances their motivation. The motivation and focus enhancement effects could be attributable to the fact that Sunifiram stimulates the release of Acetylcholine, the neurotransmitter most closely connected with cognitive ability.
How It Works
Sunifiram is known to work in two ways, both as a cholinergic that enhances the production and release of Acetylcholine and as an Ampakine that stimulates the activity of glutamine receptors. Its precise mechanisms of actions are not completely understood. However, it is thought that Sunifiram’s primary action is that of an Ampakine. This means that after crossing the BBB, it binds to AMPA-type glutamate receptors in the brain. This stimulates the production of glutamate, a crucial neurotransmitter which has the vital role in neural activation.
Glutamate is excitatory neurotransmitter which is essential to synaptic plasticity, or the ability of nerve synapses to respond to decreases and increases in activity. A sufficiency of glutamate is vital to long-term potentiation, or lasting boost in signal strength between nerve cells. This is especially important in the hippocampus, the area of the brain which has the main role in both the formation and storage of memory and spatial navigation. It is thought that much of Sunifiram’s cognitive improvement ability is achieved by increasing neural signal strength in this area of the brain.
Ampakines also work as mild stimulant that boost energy and alertness, but without restlessness and other negative side effects connected with amphetamines, Ritalin and caffeine.
Sunifiram is also believed to work as a cholinergic, boosting the production and release of the Acetylcholine. Although the exact process by which this happens has not been understood, an animal research proved that tests using piperazine compounds like Sunifiram had a cholinergic effetc similar to that of Piracetam.
Acetylcholine is narrowly connected with most aspects of cognition, including learning ability and speed, memory, and fluid intelligence. Most nootropic supplements work by stimulating the production of Acetylcholine, either by directly supplying the choline from which Acetylcholine is created or by stimulating acetylcholine receptors.
Dosage
Sunifiram is unbelievably concentrated compared even to the most powerful Racetams, such as Pramiracetam and it requires a much smaller dose than Racetams for efficiency. You will notice positive effects from a dosage as small as 4 mg. However, many users usually take between 5-8 mg in a day, and this dosage is usually considered both efficient and safe. A Sunifiram dosage of 10 mg is more likely to cause a stimulant effect similar to Adderall. Sunifiram is best taken sublingually.
It is recommended to begin with the smallest possible effective dose and build slowly as necessary. Not only is it a new supplement on which no human studied have been documented, Sunifiram is also known to be extremely strong and a too-high dosage could have unwanted side effect, such as brain fog and over-stimulation.
Also, tolerance to Sunifiram may build quickly. To avoid this problem, some people suggest cycling it with other nootropics.
Stacking
Sunifiram can be safely and efficiently stacked with other nootropic supplements. However, users are advised to be both conservative and cautious about Sunifiram doses in combination with other powerful nootropics, especially until they are certain how they personally react to Sunifiram.
Stacking for mood improvement: Sunifiram is known to stack well with Aniracetam for mood improvement. Sunifiram also stacks well with L-theanine, which increases production of GABA, dopamine and serotonin and works as glutamine reuptake inhibitor. Another good addition to this type of stack is Sulbutamine, which potentiates glutamatergic, cholinergic and dopaminergic transmission. Also, a good choline source is very important both to prevent headaches and other unpleasant side effects and as a potentiator.
Stacking for increased cognitive effects: This is probably the most usual type of Sunifiram stack. It is best accomplished by combining Sunifiram with one or more of the Racetams, such as Noopept, Piracetam and Oxiracetam. It is very important to add a good choline source, such as centrophenoxine, Alpha GPC or CDP choline to this type of stack because Racetams make a potent draw on the brain’s choline source.
Brands
Sunifiram is available with the brand Liftmode selling it in pharmaceutical grade powder form at Amazon.com.
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(max-width: 767px){#go-pricing-table-32626 .gw-go-col-wrap{width:50%}}@media only screen and (max-width: 479px){#go-pricing-table-32626 .gw-go-col-wrap{width:100%}}
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Side Effects:
No severe side effects have been documented to this date. However, it’s important to note that no human researches or clinical trials have been finished. Information from animal researches shows that Sunifiram is both well tolerated and safe, and even dosages many times larger than the effective dosage have not proven toxic.
User reported side effects are both temporary and minor and include enhanced salivation and/or perspiration, nasal stuffiness, enhance in body temperature, headache, insomnia and an increase in sensitivity to audio and visual stimulation.
Conclusion:
Sunifiram is one of the most promising and exciting new nootropics, providing powerful energy, perceptual, mood and cognitive benefits. Many people take it on a regular basis and consider it a favourite. However, Sunifiram is not a supplement to be consumed carelessly and taken lightly, because no human researches have been documented and much remains to be understood about this potent nootropic.
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CDP Choline – How Good is This Nootropic?
by Mental Hike | Dec 20, 2016 | Focus Nootropics, Memory Nootropics | 0 Comments
CDP Choline Focus Energy Mood Cognition PROS · Reduces anxiety · Promotes cognitive health · Calms stress · Supports a relaxed mood · Regulates the body · Improves long-term well-being · Enhances calmness and happiness CONS - The door gets hot when in use - Not...
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Ginkgo Biloba as a Nootropic? – Review
Ginkgo Biloba Review
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Ginkgo Biloba is one of the world’s oldest natural medicines and it is gaining a new reputation as an efficient natural nootropic. Ginkgo Biloba is a medicinal plant from traditional Chinese medicine that is commonly called „Maidenhair tree“. It was used to increase energy and treat various conditions ranging from infection to asthma.
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Today, Ginkgo Biloba is one of the top 10 most popular supplements in the west. In the traditional Chinese medicine seeds and fruit were first used, they more recently included leaf extract. The leaves of the Ginkgo tree have been used to create medical treatment for many physical ailments, including hearing problems, headaches, eye issues, bronchitis, asthma and many other conditions.
Modern studies have proven that Ginkgo Biloba increases circulation and it is being studied as a potential treatment for various conditions associated with impaired blood flow, including sexual dysfunction and headaches. It is thought to have some benefits in fighting the memory disorders associated with Alzheimer’s disease. It is also known to decrease leg cramping and pain caused by training. Ginkgo has also been proven to benefit individuals who suffer Reynaud’s Syndrome, which is a painful response to cold, particularly in the toes and fingers.
However, some of the Ginkgo Biloba’s most interesting benefits are associated with cognition, mood and memory. By enhancing blood flow and promoting circulation in the brain, Ginkgo Biloba works as a nootropic. People who use it claim it increases learning, boosts mood and promotes memory. Ginkgo is also known to work as an antioxidant, protecting the brain from free radicals and from oxidative stress.
Ginkgo Biloba is a popular addition to nootropic stack because it interacts well with other supplements and may work as a potentiator for other nootropics.
What was one thought of a folk medicine elixir is a proven memory enhancer with many other cognitive benefits, including combating Alzheimer’s disease.
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General thoughts:
Benefits
Energy booster – Ginkgo Biloba has been regarded a potent energy enhancer for many centuries. Modern studies indicate that the ancient Chinese physicians who used it as a general tonic were certainly on the right path. By promoting circulations throughout the body, Ginkgo increases oxygenation and the absorption of nutritients, enhancing endurance and making muscles perform longer and work better.
Reduce leg cramping and pain – Ginkgo Biloba has been proven to reduce training-related leg cramping and pain. Ginkgo Biloba’s circulatory properties help alleviate this problem, which is caused by insufficient blood flow. The same circulatory properties also enable Ginkgo to soothe the discomfort of Raynaud’s syndrome, a disorder in which cold temperatures induce painful vasospasms of the toes and fingers.
Mood enhancement – Ginkgo Biloba has a longstanding reputation as a memory booster and recent studies are showing that reputation to be well-earned. Many clinical studies and researches have proven that Ginkgo Biloba supplements noticeably promoted memory in individuals suffering from mild to moderate primary degenerative dementia. Although similar researches on healthy volunteers have been less conclusive, many people who use Ginkgo say that using this supplement makes their memory quicker, clearer and sharper.
Improved cognition – Ginkgo’ ability to promote circulation and blood flow in the brain makes it an effective and potent nootropic, both on its own and in combination with other nootropics. Improved cerebral blood flow results in promoted absorption of nutrients and oxygen, which in turn produces a feeling of mental alertness and clarity. It is also known to modulate the release of many crucial neurotransmitters, such as Acetylcholine, the neurotransmitter most closely connected with studying.
Improved vision – Clinical trials have proven that Ginkgo promotes vision in individuals who suffer from glaucoma. It has also been shown to benefit individuals who suffer from macular degeneration, an incurable age-connected disease in which the central part of the retina deteriorates.
Mood management – Ginkgo has been used for hundreds of years as a mood booster, and clinical trials on volunteers suffering from anxiety disorder proves that it is an efficient treatment for anxiety. Ginkgo has also been proven to be efficient mood modulator among healthy adults, and there are scientific proofs supporting its benefits for individuals suffering from depression.
How It Works
The main active components found in Ginkgo Biloba’s leaves are bilobalides, ginkgolides and flavonoids. The actions of these components make Ginkgo Biloba an antioxidant and anti-inflammatory that also decreases platelet accumulation, increases cerebral glucose utilization, affects the vasomotor system and regulates neurotransmitter release.
It is believed that the main source of Ginkgo Biloba’s power lies in its ability to enhance circulation. This supplement improves and regulates tone in the vascular system by managing thromboxane A2 and prostacyclin.
Increased circulation then creates outstanding conditions in all vital organs, particularly the brain. Maintaining a healthy blood flow to the brain is best way to enhance concentration and increase memory. It also has potential to heal migraines and headaches.
The management of blood clotting is another one of Ginkgo Biloba’s main circulatory mechanisms. Through ginkgolide B, redundant blood clotting is hampered. This can prevent many cerebrovscular problems, including thrombus and myocardial ischemia.
Enhanced circulation plays an important role in Ginkgo’s nootropic and therapeutic capabilities. Improved blood flow throughout the body decreases circulation-related cramping and pain and makes muscle work better. Increased cerebral circulation makes the brain works more effectively, absorbing nutrients and oxygen quicker and more thoroughly.
Ginkgo Biloba is also natural monoamine oxidase (MAO) inhibitor. This function is a crucial regulator of mental confidence and good mood. It prevents loss of key energy and mood hormones like norepinephrine, serotonin and dopamine. Also, Ginkgo’s cyanogenic glycosides attack harmful fungus and bacteria throughout the body.
Ginkgo Dosage
Although Ginkgo Biloba has been used since at least 2500 BC, the Food and Drug Administration (FDA) has still not held a formal Ginkgo review. As a result, there is no official recommended dosage.
However, Ginkgo dosages of up to 360 mg in one day (split into 3 dosages) have been tested and found to be both efficient and safe.
If used as a daily supplement for the prevention of cognitive decline and for overall brain health, taking 40 to 120 mg dosages one to three times a day is usually recommended. For a fast mental boost of mental performance, a single dosage of 120 mg a few hours before the task should be a nice starting point.
The daily total amount of Ginkgo can be taken all at once or spread over 2 to 3 dosages. Ginkgo Biloba should usually be taken with food.
Stacking
Ginkgo is a popular natural nootropic which works very well on its own but truly shines when combined with other supplements. Ginkgo is often referred to as the „neutral nootropic“ and some people who take Ginkgo claim its cognition increasing effects are best achieved when it is stacked or combined with other supplements.
Ginkgo, Gotu Kola and Ashwagandha
Gotu Kola is a reputable natural supplement known primarily for boosting energy, and it also promotes conditions of chronic venous insufficiency and positively effects cardiovascular health. Ashwagandha is an ancient herbal nootropic which dates back to Ayuervedic medicine. It is known mainly for its potent anti-anxiety effects, but it also increases cognition and mood.
Ginkgo and Vinpocetine Stack
Vinpocetine is a natural nootropic and it is best known as a memory increaser. Like Ginkgo, Vinpocetine has been proven to work as a brain protectant and to promote blood circulation.
Brands
When shopping around for Ginkgo Biloba, make sure that you look out for the following brands, because these are regarded to be the top 5 Ginkgo supplements available in the market today.
Now Foods Ginkgo Biloba
Cardiovascular Research Ginkgo Biloba
Jarrow Formulas Ginkgo Biloba
Natrol Ginkgo Biloba
Advanced Ginkgo Smart
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Side Effects:
As shown by its many centuries of use as a folk medicine, Ginkgo Biloba is mostly without severe side effects for most individuals. Some minor side effects including gas, heart palpitations, headaches and nausea may happen in some cases, but it is not the norm. These side effects are rare and are generally temporary. However, you it is recommended to reduce a dose if you experience them.
Ginkgo supplements are derived from the leaves of ginkgo tree. However, consuming extracts made from the ginkgo seeds or eating the seeds of the ginkgo tree can cause dangerous seizures.
People who are using antidepressants, anticoagulants or anticonvulsants or who have just had surgery are recommended to avoid using Ginkgo Biloba. Also, small children, women who are expecting a baby or breastfeeding are recommended to avoid this supplement.
Conclusion:
Ginkgo is one of the most widely available supplements. It is both available in storefronts and can also be purchased online. Ginkgo is available in both capsule and powder form. It is recommended to buy Gingo in bulk powder form from PowderCity.com if you want to use Ginkgo over the long-term and would like a more inexpensive option.
Ginkgo Biloba is used as both a general tonic and a specific treatment for many centuries. It is currently being tested as a potential treatment for many memory-related and circulatory disorders. Ginkgo can promote cognition and memory, increase energy, and work as a strong potentiator in combination with other supplements. Ginkgo is affordable, very well-tolerated, safe and readily available everywhere.
Ginkgo is a supplement that’s well worth a try if you want to make the most of your body and brain.
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Ginkgo Biloba as a Nootropic? – Review
by Mental Hike | Dec 24, 2016 | Memory Nootropics | 0 Comments
Ginkgo Biloba Review Focus Energy Mood Cognition PROS · Reduces anxiety · Promotes cognitive health · Calms stress · Supports a relaxed mood · Regulates the body · Improves long-term well-being · Enhances calmness and happiness CONS - The door gets hot when in use -...
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CDP Choline – How Good is This Nootropic?
by Mental Hike | Dec 20, 2016 | Focus Nootropics, Memory Nootropics | 0 Comments
CDP Choline Focus Energy Mood Cognition PROS · Reduces anxiety · Promotes cognitive health · Calms stress · Supports a relaxed mood · Regulates the body · Improves long-term well-being · Enhances calmness and happiness CONS - The door gets hot when in use - Not...
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The post Ginkgo Biloba as a Nootropic? – Review appeared first on It Made My Day.
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Galantamine Review – Nootropic for Memory
Galantamine Review
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Galantamine is an alkaloid first derived from the flowers of a plant called Galanthus Caucasius (AKA Snowdrop). This natural supplement has been used for hundreds of years in China as a memory booster. It was even noted by the ancient Greeks for it potent mind-stimulating effect. The synthetic supplement formulation of Galantamine was first produced in 1959 in Bulgaria.
Since then, Galantamine has been used regularly throughout Europe as a treatment for many diseases and disorders, including myopathy, myasthenia and many types of motor or sensory dysfunctions.
It is known that this supplement indirectly improves dreaming sleep and also lucid dreaming, which is the art of becoming self-aware in your dreams.
Product Description:
Galantamine is extremely popular nootropic supplement for increased intellectual capacities and memory enhancements. This supplement is approved by the Us Food and Drug Administration (FDA) as a treatment for Alzheimer’s disease in 2001. Galantamine is available as both a prescription drug and over the counter drug. There are some possible side effects connected with the use of Galantamine but if you are using it as recommended you will probably not experience any negative and unwanted effects.
You can take Galantamine with a cholinergic supplement like Citicoline or Alpha GPC to optimize your Acetylcholine levels. It is also fairly usual to use Galantamine in combination with Racetams like Aniracetam and Piracetam.
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General thoughts:
Benefits
The main benefit of this supplement is as a cognitive booster or nootropic supplement. The boost of Acetylcholine is key to these demulcent effects because the neurotransmitter is believed to have a main role in learning and memory.
Many people who use Galantamine will experience an increased learning capacity, increased and lengthened concentration and attention span and boost in memory formation.
Also, in some cases sensory perception may be increased resulting in things like sounds becoming sharper and colors brighter.
Another interesting benefit of this supplement is that of helping you to have lucid dreams. This type of dream is one in which you know that you are dreaming. Galantamine also has many benefits in related to improving deep high-quality sleep. The compound acts instantly to enhance the duration of REM sleep, and this will make your dreams clearer and more memorable.
How It Works
Galantamine is believed to have a dual mode of action.
The first part of this activity is that it modulates nicotinic receptors on brain cells. These are extremely important synaptic sites which are responsive to Acetylcholine and many other brain chemicals like nicotine. Galantamine helps to change them in such a way as to maintain their functional and numerical integrity.
The second action of Galantamine is to block specific enzymes and enzymatic activity within the brain.
Galantamine is an acetylcholinesterase inhibitor. This means that it prevents the Acetylcholine from breaking down acetylcholine. The Acetylcholine is involved in some of the most crucial signalling in the brain related to attention, cognition and memory.
As you are getting older, levels of this neurotransmitter decrease naturally and acetylcholine activity is especially low in people who suffer Alzheimer’s disease and other types of senile cognitive disorders. By moderately enhancing Acetylcholine level in the brain, Galantamine can contribute to greater clarity of thought and better mental performance.
Dosage
The generally recommended dose range of Galantamine is between 4 and 24 mg in one day. The specifics should be determined by the reason for use. The generally accepted dosage for dream improvement is on the low side: 4 to 8 mg in one day. A lucid dreamer will need to take during the night and also during the day. On the other hand, people who suffer Alzheimer’s disease often take 12 mg or more in one day. On rare occasions, going up to the maximum Galantamine dosage of 24 mg would be allowable. Taken orally, this supplement is active and at full strength within 60 minutes of ingestion. The half-life of Galantamine is 5 to 6 hours.
It’s recommended to take Galantamine in the middle of the night to take advantage of the longer REM cycles which happen in the second half of the night. Taking this supplement before you go to sleep may have the opposite of the desired effect and may result in unwanted experiences.
It is recommended to begin with the lowest effective dosage and only after becoming familiar with how it affects your body chemistry work your way up.
Galantamine has been known to build up tolerance. For this reason it is recommended to use it as part of cycle with at least as much down time as usage.
Stacking
You may want to use Galantamine with a cholinergic supplement like Citicoline or Alpha GPC to optimize your Acetylcholine levels. The use of choline supplements and Galantamine has become recognized as one of the most effective combinations for inducing lucid dreams.
Also this potent nootropic stack can have extremely positive results for mental clarity, focus and memory. Choline and Galantamine share similar pathways in the brain. Both these supplements work to enhance acetylcholine transmission in a synergistic manner.
It is also fairy usual to use Galantamine in combination with Racetams, such as Aniracetam and Piracetam.
Brands
In the UK Galantamine is available under the drug name Reminyl. Other brand names are Razadyne and Razadyne ER. In US there are AbsorbHealth and PeakNootropics as top brands that sell them.
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(max-width: 767px){#go-pricing-table-32626 .gw-go-col-wrap{width:50%}}@media only screen and (max-width: 479px){#go-pricing-table-32626 .gw-go-col-wrap{width:100%}}
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Side Effects:
While Galantamine is regarded to be generally well tolerated and very safe, there are some unwanted and unpleasant effects. Individuals who are allergic to daffodil plants may also be allergic to Galantamine. Drugs with anticholinergic effects and which cross brain/blood barrier, like Artane (trihexyphenidyl), Cogentin (benztropine) and atropine counteract the effects of Galantamine.
The usual side effects include headaches, tiredness, loss of appetite, dizziness and nausea. Also, the following medical problems have been reported to be worsened or irritated by the use of Galantamine: heart problems, including heart murmur or slow heartbeat, urinary tract issues, liver and/or kidney issues, asthma, stomach ulcer, epilepsy or history of seizure and lung disease. If any types of medical problems or allergic reactions develop, immediately discontinue use and consult your doctor.
Conclusion:
Galantamine is a highly effective nootropic which does produce a lot of benefits in regards to memory and studying. While there are some possible side effects associated with its use, if you are taking it as directed you will most likely not encounter any negative effects.
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