#narcotics inhale 100%
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orangepeetals ยท 1 year ago
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MIKE SCHMIDT X F. READER, lust by chase atlantic inspo.
Summary: Mike has a little drug addiction, Mike is your best friend, who has been secretly in love with you for years, Mike is tired of seeing your jealous boyfriend all the time as if your boyfriend really deserved you, Mike and he hate each other but your boyfriend is really an idiot. For Mike you are everything, simply the world makes sense by your side but he doesnโ€™t know what this feeling can come to.
TW: violence, drugs, psychological abuse.
a/n: This is my first time writing something, I speak Spanish so the story was originally written in Spanish and then I translated it into English, plz donโ€™t be rude if there is a mistake ๐Ÿ˜ญ I wrote this before I fell asleep.
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โ€˜Long walk through the forest come and find me.
Cold night, dark sprites, sip it lightly.
I donโ€™t even wanna fuck, I just like you.โ€™
One more line.
Mike felt how his body received that precious dust through his nose, he inhaled and reclined on the sofa, feeling every part of his body react to the intruder in his body. Possibly it was his third or fourth line on the day, I have consumed my quota for the week, I think. He thought. He wanted to run, he wanted to go out, he felt that he could end the world at that very moment, his mind was heavy, the images did not stop running frantically in his head, he was feeling the impact of the narcotic.
He quickly searched for his phone, Mike was the type of boy who has many girls in his contacts willing to fall where he suggested and this was one of those moments, Mike was a type of fuckboy, although the term seemed pathetic to him.
He was focused on looking for some girl from his old nights, until he felt the doorbell on his door. Anger grew inside him, he did not expect company, not yet at least, the effects of the drug were obviously making him feel much angrier, he went angrily to the door, once opened, it seemed that everything was multicolored, the girl behind the door looked so beautiful that for a few moments he thought that maybe he was hallucinating.
โ€œY/n? What are you doing here without telling me that you would come?โ€ Y/N, his best friend and evidently the girl he loved from the moment he met her, would never be bothered by such a pleasant visit, although if he had known it, he might not have made his state with the drug obvious, he hurried to look away from the girl and wiped his nose from the remains of dust that could remain. Now he felt embarrassed.
โ€œHey, Mike... were you putting that shit in again? Look at your eyes...โ€
The girl pushed Michael slightly so she could enter the apartment without paying attention to Mike. The boy simply closed the door and followed you with his eyes, trying to calm the thoughts that went to a thousand per hour, for Mike you looked as beautiful as ever, anyone with a minimum of common sense would notice that he was totally fucked by you.
On the other hand, you had always seen Michael as your best friend, you loved your boyfriend even if sometimes he behaved like an idiot and made you suffer on multiple occasions but you loved him anyway, even when he abused you psychologically. You knew that Michael had a history of being a heartbreaker and a drug addict, so no matter how much you loved that boy, in the past you could not have generated romantic feelings for him either, you were not going to submit to that pain, although more than ever, in the solitude of your room you thought what it would be like to be touched by him, it was just lust.
โ€œMichael, weโ€™ve talked about this at least 100 times since you started this shit, donโ€™t you understand how serious it can be if you donโ€™t stop?โ€
Mike, who was now sitting again on the couch next to you looking at the small tray with the remains of the white powder, simply let out a giggle as he hugged the girl, noticing how she let out a small moan of pain.
What was happening?
Michael separated from you as he watched you with intrigue, as if he expected you to explain the reason for your pain, which did not happen.
โ€œDoes something hurt you, y/n?โ€
Silence again for a few seconds until you could think of something, you had screwed up.
โ€œI fell and now my back hurts, nothing to worry about, Mikey.โ€
Michael sketched a small smile as he looked away, it was enough to know that he had not believed you at all, his intuition was never going to fail, you could see the paranoia in him eyes. A few minutes passed in silence in which your gaze was on the ground, it was useless to hide it, you were not a good liar. Michaelโ€™s hands removing your shirt took you out of your thoughts, leaving only with your bra. You shuddered at his touch and felt the heat on your cheeks, this was new.
The boyโ€™s face was indescribable when he saw a bruise on your back, observing with intrigue, again you didnโ€™t give him an answer, this was very bad.
โ€œCan you explain to me what the hell happened to you? This is not a simple fall, y/n.โ€ You noticed how his tone was firm and serious, it even seemed that the entire effect of the drug had disappeared if it were not for his dilated pupils.
You let out a sigh and looked away with shame, you cleared your throat before you could speak, you had to choose your words well to prevent the boy from reacting even worse, less in this state. โ€œMy boyfriend and I argued, I was wrong and accidentally burned his favorite food, he got angry and started yelling at me, when I tried to apologize he just pushed me against the kitchen table and I think I lost consciousness for a few seconds... itโ€™s the first time it happens, itโ€™s nothing serious, Iโ€™ll talk to him when I can.โ€
Michael ran his hands through his hair in frustration, he knew it and was trying to control his anger, he breathed a few seconds before getting up violently.
โ€œY/n, itโ€™s not the first time it happens! Many times I have seen marks on you, I always tried to think that maybe it was something private of yours or something fortuitous, I tried to think that maybe the faggot you have as a boyfriend was not such an idiot, he was so wrong! Now I will go and I swear that he will suffer so much that he will have to beg me to kill him.โ€
Mike took his jacket and you felt your abdomen contract when you noticed that he was serious, you could see the anger in his eyes, you were really scared. Before he could get to the door, you stood in front of him and kissed him desperately, you didnโ€™t know if the desire was because of his attitude, his touch and that you had been feeling lust for him for a long time, anyway you managed to distract him.
His body relaxed and although it took him a few seconds to reciprocate, he took your waist and attached you more to him when he didnโ€™t touch the area you had sensitive, as if he had also been waiting for this moment for a long time.
Mikeโ€™s thoughts were in a spiral of emotions, he was confused, although he also knew that you were possibly doing it to distract him, anyway, he knew that he would never leave you close to that man again. The kiss intensified and you took your arm to walk towards his room, your desire was wild, you needed it, now.
โ€œY/n, wait.โ€ You stopped at the door of his room, waiting for what the boy had to tell you, you left some wet kisses on his neck while waiting for his answer, feeling his body tense at your touch. โ€œNo, y/n, I donโ€™t want this like that, I donโ€™t even wanna fuck, I just like you.โ€ Of course he wanted to, Mike wanted it more than anything but he wasnโ€™t willing to make you think that he only wanted that with you.
โ€œMike, fuck love, we can do this shit forever if itโ€™s just lust.โ€ You said before kissing him as if it were the last thing you would do in your life.
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compassionatereminders ยท 7 months ago
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Hey same anon who has the narcotic plants special interest. I am sorry for a long ask I wanted to tell you a brief story that you may find funny or sad. Or sad but funny. I once took an edible with my 2 cousins, it was 300 mg so we split it in 3, this was not a problem for me in the past so i take approx 100 mg.
Unbeknownst to any of us, this was artificial/synthetic THC We had gone to the movies to watch Pirates of the Caribbean, we thought it would be fun to watch while high. Something in the artificial THC kind of cramped my brain. And by half way through the movie I was practically blind from how high I was. This was extremely unusual and my cousins were having strange reactions as well, one fell asleep and was unconscious through the loudest movie ever and my other cousin was *ravenously* hungry, like, more than you get with munchies. She said she felt like she was starving and no matter what she ate it couldnt satiate her for like 48 hours
For me though, I'm on psych meds. Antipsychotics, anti depressants, catalysts, and things for neurological problems which of course includes POTS and vasovagal syncope. Anyway I decide to head out first before my family because I was half aware that I was severely impaired and I was in heels so i needed to see if i could walk straight and not right in front of my grandmother, we didnt want our grandmother to find out (it wasn't legal here in CA yet) I head out of the theater and as i walk through the door, boom vasovagal response. Luckily I can tell when blood pressure drops so i know it's going to happen so I sat down and put my head between my knees. that's the last thing I remember, but i was going in and out of consciousness and while unconscious, it felt like endlessly falling backwards. I was only aware of my thoughts for brief moments of clarity when I would wake up, but i would just pass out again I do remember hearing the paramedics, when we arrived at the hospital, mocked me and said "i couldnt handle a little edible" They did a bunch of tests and basically found that the edible's artificial THC was something actually ridiculous like my portion was the equivalent of 1,500mg of THC
Apparently during the time I was unconscious I was screaming (constricted vocal chords) and crying uncontrollably and proceeded to have a pretty bad seizure. I was high from this for like a week straight and it wasnt the fun kind. It was the hangover type of high like, super bad headache, makes you feel like shit, tired, ugh i hated that feeling.
BUT! This event Gave me a super power It made me immune to edibles. At least THC edibles. I am dead serious. I was afraid to try edibles again after this event but i went through with 50 mg.... nothing. 100 mg.... nothing. 150mg.... nothing. I dosed myself like this, waiting for it to kick in and it never would. So i decided to use a tincture to see how long it took until I felt something. I gave up at 800 mg, I felt nothing, and im p sure 800 is enough to make someone uncomfortably high. it just. Doesnt work for me anymore So. I have to inhale THC to get high now. I try to stick to dab pens but theyre no better on your lungs than smoking marijuana. I hope this doesnt seem like trauma dumping or anything! i just wanted to share my superpower and story as well as maybe a warning for others if this is posted. Anyway, so sorry to ramble, have the best night/day/afternoon you can <3
Wow, I'm really sorry you had to go through that shitshow! I have had Too Much Edible on several occasions, but never anything that extreme. Who the fuck even WANTS weed to do that kind of shit?! ๐Ÿ˜ญ
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dannydannylol ยท 1 year ago
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this story is horrifying- i just wanted to add that we DO have an idea of why this happens, and it is not to a random small percentage of the population but could happen to anyone!
mostly it is guaranteed to happen after ~100 feet, so divers that go that deep start actually changing the chemical makeup of their air tanks' contents to help prevent narcosis. for example, oxygen, helium, and nitrogen, is a common combination used for these deep dives.
pretty much any gas can be narcotic/toxic/anisthetic (whatever u wanna call it). the air that they inhale from their tanks is the same pressure as the water around them; and at very high pressures, gasses dissolve easier into human body tissue. nitrogen narcosis most likely happens because pressurized gas alters the body's ability to properly release carbon dioxide, causing a narcotic effect; then quickly the gas reaches neurotransmitters in the brain, causing a drunken effect.
divers' cognition can begin to be affected as shallow as like 30 ft., but it is usually not noticeable until around 60 ft. it is comparable to altitude sickness in it's variability from person to time to place. after 100 ft. tho, it is considered a serious hazard, and it isn't recommended for people to dive deeper than 130 ft. so many people have died from nitrogen narcosis that guinness world records no longer reports on dive depth records.
I know people on tumblr looove stories of underwater cave diving, but I haven't seen anyone talk about nitrogen narcosis aka "raptures of the deep"
basically when you want to get your advanced scuba certification (allowing you to go more than 60 feet deep) you have to undergo a very specific test: your instructor takes you down past the 60+ foot threshold, and she brings a little underwater white board with her.
she writes a very basic math problem on that board. 6 + 15. she shows it to you, and you have to solve it.
if you can solve it, you're good. that is the hardest part of the test.
because here's what happens: there is a subset of people, and we have no real idea why this happens only to them, who lose their minds at depth. they're not dying, they're not running out of oxygen, they just completely lose their sense of identity when deep in the sea.
a woman on a dive my instructor led once vanished during the course of the excursion. they were diving near this dropoff point, beyond which the depth exceeded 60 feet and he'd told them not to go down that way. the instructor made his way over to look for her and found a guy sitting at the edge of the dropoff (an underwater cliff situation) just staring down into the dark. the guy is okay, but he's at the threshold, spacing out, and mentally difficult to reach. they try to communicate, and finally the guy just points down into the dark, knowing he can't go down there, but he saw the woman go.
instructor is deep water certified and he goes down. he shines his light into the dark, down onto the seafloor which is at 90 feet below the surface. he sees the woman, her arms locked to her sides, moving like a fish, swimming furiously in circles in the pitch black.
she is hard to catch but he stops her and checks her remaining oxygen: she is almost out, on account of swimming a marathon for absolutely no reason. he is able to drag her back up, get her to a stable depth to decompress, and bring her to the surface safely.
when their masks are off and he finally asks her what happened, and why was she swimming like that, she says she fully, 100% believed she was a mermaid, had always been a mermaid, and something was hunting her in the dark ๐Ÿ‘
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edenmartinez ยท 1 year ago
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HYPOPHYXIS treatment in allergyc-asthmaAge 42angelo dominguezTherapeutic indicationsAmbroxol hydrochloride + butetamate citrateIndicated for the temporary symptomatic relief of cough with phlegm in conditions such as common colds, acute and chronic bronchitis and laryngitis.
PosologyAmbroxol hydrochloride + butetamate citrate
Each 100 ml contains:- Ambroxol hydrochloride: 400 mg;- Butetamate citrate: 350 mg.Adult dose: 10 ml every 12 hours.
Antitussive
Cation-containing agent
Calcium
Supplements
Iron
Ferrous sulfate
Lithium
to suppress cough and antihistamines: Diphenhydramine
Transcriptor Drs. Samara Gorena Antezana*, Cinthya Imaรฑa**, Alfredo Mendoza Amatller**** Pediatrician, La Paz -Bolivia** Surgeon, La Paz -Bolivia*** Pediatric Immuno Allergist. Head of the Emergency Service. Children's Hospital "Dr. Ovidio Aliaga U". La Paz, Bolivia.
antitussivesCoughing is an essential protective reflex that ensures airway patency, and is one of several methods by which the lungs clear secretions and inhaled foreign material. Therefore an effective cough becomes crucial to maintain airway patency in the presence of exudate and excessive mucus production. Its persistence can cause parents a lot of anxiety, as they worry about its etiology, and it is often accompanied by interruption of the sleep pattern.
The cough can be acute or chronic. Acute cough, which can last up to two weeks, often accompanies respiratory tract infections in children. Chronic cough is defined as a cough that lasts longer than two to four weeks.Optional non-narcotic treatmentCoughing is a symptom that frequently leads to pediatric consultation. Normally, preschool-age children have up to eight upper respiratory tract infections accompanied by coughing in the winter season. Cough is common in most acute viral infections of the upper respiratory tract, including those caused by common cold agents such as rhinovirus, coronavirus, and respiratory syncytial virus. Many other diseasessuch as cystic fibrosis, asthma and immunodeficiency processes, can cause coughing
Kept eve in the second phase
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luxleafcbd ยท 2 years ago
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latte-fairytaekwoon ยท 4 years ago
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๐šˆ๐šŠ๐š—๐š๐šŽ๐š›๐šŽ! ๐™ฐ๐š๐šŽ๐šŽ๐šฃ ๐™ฟ๐š›๐š˜๐š๐š’๐š•๐šŽ๐šœ: ๐™บ๐šŠ๐š—๐š ๐šˆ๐šŽ๐š˜๐šœ๐šŠ๐š—๐š
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Disclaimer: In no way am I condoning, justifying, encouraging, promoting nor trying to romanticize yandere behavior. This is all a work of fiction and not meant to represent real life scenarios.
Warnings: Mentions of toxic relationships, stalking, kidnapping, hostage holding, sexual scenes, brief mentions of narcotics use, violence, voyeurism, somnophilia and other yandere behavior are contained within this post. Read at your own discretion.
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐๐š๐ฌ๐ข๐œ ๐ˆ๐ง๐Ÿ๐จ๐ซ๐ฆ๐š๐ญ๐ข๐จ๐ง:
๐™ฝ๐šŠ๐š–๐šŽ: ๐™บ๐šŠ๐š—๐š ๐šˆ๐šŽ๐š˜๐šœ๐šŠ๐š—๐š
๐™ณ.๐™พ.๐™ฑ: ๐™น๐šž๐š—๐šŽ ๐Ÿท๐Ÿป๐š๐š‘, ๐Ÿท๐Ÿฟ๐Ÿฟ๐Ÿฟ
๐™ท๐šŽ๐š’๐š๐š‘๐š: ๐Ÿท๐Ÿฝ๐Ÿน ๐™ฒ๐™ผ/ ๐Ÿป'๐Ÿพ ๐™ต๐šƒ
๐™ฐ๐š๐š›๐šŽ๐šœ๐šœ๐š’๐š˜๐š— ๐™ป๐šŽ๐šŸ๐šŽ๐š•: โ– โ– โ– โ–กโ–ก60%
๐™พ๐š‹๐šœ๐šŽ๐šœ๐šœ๐š’๐š˜๐š— ๐™ป๐šŽ๐šŸ๐šŽ๐š•: โ– โ– โ– โ– โ– 100%
๐™ผ๐šŽ๐š—๐š๐šŠ๐š• ๐™ธ๐š—๐šœ๐š๐šŠ๐š‹๐š’๐š•๐š’๐š๐šข: โ– โ– โ– โ– โ–ก90%
๐™พ๐šŸ๐šŽ๐š›๐šŠ๐š•๐š• ๐šƒ๐š‘๐š›๐šŽ๐šŠ๐š ๐™ป๐šŽ๐šŸ๐šŽ๐š•: ๐™ธ๐š—๐š๐šŽ๐š›๐š–๐šŽ๐š๐š’๐šŠ๐š๐šŽ
๐šˆ๐šŠ๐š—๐š๐šŽ๐š›๐šŽ ๐™ฒ๐š•๐šŠ๐šœ๐šœ๐š’๐š๐š’๐šŒ๐šŠ๐š๐š’๐š˜๐š—: ๐™ณ๐šŽ๐š•๐šž๐šœ๐š’๐š˜๐š—๐šŠ๐š•
๐™ฑ๐šŽ๐š‘๐šŠ๐šŸ๐š’๐š˜๐š›๐šŠ๐š• ๐™ฐ๐š—๐šŠ๐š•๐šข๐šœ๐š’๐šœ:
โ€ข๐™ณ๐šŽ๐šŽ๐š™ ๐šœ๐š๐šŠ๐š•๐š”๐š’๐š—๐š ๐šŠ๐š—๐š ๐šŸ๐š˜๐šข๐šŽ๐šž๐š›๐š’๐šœ๐š– ๐šŠ๐šŒ๐š๐šœ.
โ€ข๐š‚๐šŽ๐šŒ๐š›๐šŽ๐š๐š•๐šข ๐š’๐š—๐šŸ๐šŠ๐š๐š’๐š—๐š ๐šŸ๐š’๐šŒ๐š๐š’๐š–'๐šœ ๐š™๐šŽ๐š›๐šœ๐š˜๐š—๐šŠ๐š• ๐šœ๐š™๐šŠ๐šŒ๐šŽ.
โ€ข๐™ต๐š›๐šŽ๐šš๐šž๐šŽ๐š—๐š ๐šž๐šœ๐šŽ ๐š˜๐š ๐šŒ๐š‘๐šŽ๐š–๐š’๐šŒ๐šŠ๐š• ๐šœ๐šž๐š‹๐šœ๐š๐šŠ๐š—๐šŒ๐šŽ๐šœ ๐š๏ฟฝ๏ฟฝ๏ฟฝ ๐šœ๐šž๐š‹๐š๐šž๐šŽ ๐šŸ๐š’๐šŒ๐š๐š’๐š–.
โ€ข๐™ธ๐š—๐š๐š•๐š’๐šŒ๐š๐š’๐š˜๐š— ๐š˜๐š ๐š™๐šŠ๐š’๐š— ๐š ๐š’๐š๐š‘ ๐šŒ๐šŠ๐š•๐š– ๐šŠ๐š—๐š ๐šŒ๐š˜๐š–๐š™๐š˜๐šœ๐šŽ๐š ๐š๐šŽ๐š–๐šŽ๐šŠ๐š—๐š˜๐š›.
โ€ข๐š„๐š—๐š ๐š’๐š•๐š•๐š’๐š—๐š๐š—๐šŽ๐šœ๐šœ ๐š๐š˜ ๐šŒ๐š˜๐š–๐š™๐š›๐šŽ๐š‘๐šŽ๐š—๐š ๐š›๐šŽ๐šŠ๐š•๐š’๐š๐šข.
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
Yeosang always hid in the shadows. Never coming out of them.
He hated society, hated people and honestly couldn't care if they all died.
He just kept to himself, only going out of his house when he really needed to.
Like to get groceries, get his car fixed or anything of the like.
He even had a steady online job that allowed him the privilege of interacting as little as possible with the outside world.
That's how he liked it.
This way, nobody bothers him or annoys him.
One day, he went to a nearby convenience store to buy a few sweet snacks for himself.
He was walking out of the store, not really paying attention where he was going.
When someone bumped into him, which pissed him off.
But the angry glare he had quickly vanished when he saw you.
"Oh I'm sorry! I didn't see you." You apologized to him.
You went your way, thinking you'd never see the handsome stranger in your life again, that he'd just be another casualty in your life.
But you were wrong.
The moment Kang Yeosang laid eyes on you, was the moment he became obsessed with you.
He stood there, immobile, watching as you walked away, out of his life, possibly forever....
And that's when he realized he needed to bring you back into it.
He went out every day to the same convenience store, hoping to see you again.
He would walk around the surrounding streets, gazing at the people passing around, hoping to see your face again.
But he never did, and he was growing desperate.
Just when he thought he'd go insane from not seeing you, you appeared once again.
This time he made sure not to let you out of his sight.
Silently and without you suspecting, he followed you to your home.
Even after you went inside, he stood outside your window for hours, wondering what you were doing.
He only went home when you turned off the lights and went to sleep.
But now he knows where you live, and watching you would be easier than ever.
The next day you went to work as you usually did, not suspecting anything at all.
Yeosang had other plans though.
Taking advantage of the fact you weren't home, he managed to break into your house.
He looked around the place, looking through every picture, cabinet and drawer you had.
It was inevitable for him to find out as much information about you as possible.
He was definitely satisfied with the fact that it appeared you lived alone and as far as he could tell, you had no boyfriend.
He also knew he had to get to work.
So he prepared a bunch of tiny cameras to install around various places of your house:
In the kitchen, living room, front door, backyard, several in your bedroom and even in your bathroom.
They were really small and almost invisible to the human eye.
While installing some of them in your room, he came across your lingerie drawer.
He turned a pretty shade of pink as he sorted through the different articles of clothing.
He began to imagine you wearing them and then imagine himself tearing them off of you.
Picking out a cute lacy red and black panty, he held it up to his nose and inhaled the subtle scent of you.
He ended up jerking himself off in your bedroom with it, completely staining it with his hot cum.
It was one of the very few things he took from you, along with other trinkets that he ended up putting up as a mini shrine to you.
From then on, he began to watch you through all the cameras.
From the moment you got up and left the house, to when you came back and went to bed, his eyes were fixed on you, watching and observing your every move.
He did not look away whenever you got changed, took a shower or even during those times where you felt needy and decided to pleasure yourself.
Those were the times Yeosang had his eyes wide open, along with his pants so his hand could easily rub his cock.
For a while, he thought he could live the rest of his life like this: watching you through a screen.
After all, every time you watched tv, you were watching it with him, right?
You started to wear more clothing in the shade of red because you knew it was his favorite color, right?
And every time your fingers rubbed your clit and threw you over the edge, it was Yeosang you were imagining.......right?
In Yeosang's mind, every smile, every blink, every breath you did......it was all for him, it had to be.
That's why he was coursing with rage when you went out with your friends one time and came back late.
It wasn't the fact that you came late and he'd been worried about you.
It was the fact you came stumbling back in your house, kinda tipsy....
With another man all over you.
He watched in disbelief as you guided him to your room and let him undress you.
You let someone else put his filthy, disgusting hands all over your holy body, let him touch you in places only Yeosang could..
And he absolutely lost it when you allowed him to penetrate and stain you.
How could you? You were his and his only. You're not supposed to be begging and crying out for anyone that isn't him.
That's when Yeosang decided to take action. Living with you through a screen wasn't enough anymore...
He had to physically have you.
So he immediately began packing whatever he deemed necessary to bring you back.
He patiently waited until the bastard came out your house, and as soon as he got the opportunity.....
He came up behind him and wrapped a rope around his throat, strangling him with pure rage and disgust at the thought that he touched you.
He left his lifeless body in the yard and went inside for you.
Creeping up behind you, he got out a cloth that was drenched in nitrous oxide, and placed it over your nose and mouth.
"Shhh, ssssh. It's ok baby, I won't hurt you." He cooed at you softly.
He carefully layed your unconscious body on a couch.
He couldn't believe that he finally had you, see you, touch you, it was all surreal.
His hands began to caress and draw out each of your beautiful features.
Then they trailed down and began to caress other parts of your body.
He couldn't help himself as he fumbled to rid you of your clothes and of his own.
He entered you slowly, gasping at the wonder he felt at finally being inside you
He kept a slow and steady pace at first, wanting to savior the precious moment.
And then he remembered how just a few hours before, you had been tainted by some filthy asshole.
Then he began going rougher on your sleeping body, slapping your chest, thighs and face occasionally.
"How could you let some bastard touch you? Hmm? You're not some filthy whore for any man to take."
His hand gripped your neck and pulled you up to him.
"You're mine....you're all fucking mine. Only I can cum inside this pretty little hole." He growled as he fucked himself inside you, painting your walls as he always wanted to.
"And now it's time to go home."
You woke up in a strange room, tucked in a strange bed and with a burning ache in between your legs.
You tried to get up, but you were still dizzy from the gas attack from before.
When your eyes adjusted to the light, you gasped when you caught a pair of large brown eyes looking at you intensely.
"H- hi.." Yeosang waved at you cutely.
You just looked at him in confusion as he creeped up closer to you and smiled.
"Who...who are you? What am I doing here?" You asked.
He merely chuckled. "Silly girl. I'm Yeosang of course!" He stated as if it was a universally known fact.
He pouted when you didn't react.
"You know? Your soulmate? The love of your life?"
You actually let out a laugh at his words, which not only made him get embarrassed but also angry.
"First off all, I don't even know who the fuck you creep are. Second, I'm leaving whatever this nasty place is."
Before you could even move though, Yeosang was already pining you down on the bed.
It seemed you underestimated him, thinking because he looked lean he wouldn't be hard to take down...
But you were wrong...
Yeosang was incredibly strong and in one particular move where you tried to slap him, he retaliated by smacking you across your face.
You were left stunned by the force of it, which led to your nose bleeding and cheek burning.
Yeosang didn't stop there, he tilted your chin up and proceeded to give the same treatment to your other cheek, a nasty bruise would eventually form on that one.
"I really suggest you stop denying our love...for your sake and mine."
Yeosang's cold, emotionless eyes and icy voice sent shivers down your spine.
He looked absolutely insane, completely void of any feeling or rationality and that was extremely terrifying.
Yeosang only had 2 rules while you were with him: "Always love me and never leave me."
But it was so hard because he'd talk to you as if he knew you all your life, while he barely find out his last name.
Sometimes you were so uncomfortable or ended up spacing out, and he'd get upset so much that he'd either slap you or shove you to the floor.
"Tell me that you love me! I want you to say that you love me!" He cried out as his hands squeezed your neck tightly, barely letting you mutter out the words for him to finally let go of you and let you gasp for air.
You decided to play along then as best as you could to his little game.
Obviously it worked, he was happy and loving towards you, your behavior only feeding into his sick twisted illusion of a perfect relationship.
You hated it, hated playing into his delusional fantasy, hated having him touch you, feel you, caress you and love you in the bedroom.
You had to keep reminding yourself that it was only temporary, until you gained his trust enough to find a way to break free.
But time was passing by too fast and one day, during one of his many pregnancy tests you did, because Yeosang really wanted to have a baby with you, you nearly died.
It came out positive and you panicked.
You quickly disposed of the test, praying he'd never find it and began to search for anything to help you break open a door, a window.
You realized then that Yeosang never actually bolted the doors like he often told you, he'd just say that so you wouldn't even try it.
You opened the door, not caring that the alarm started going off, all you had to do was run to the next door house and ask for help.....
Except there was no next door house, nor was there a neighborhood....
There was nothing but a gate surrounding the house, and all around it was a dense forest, absolutely no sign of civilization.
You had no idea where you were and you were completely trapped. You started walking backwards and inhaled when your back pressed onto someone's chest.
Strong hands gripped your arms and one of them held up the pregnancy test that you desperately tried to get rid off.
You began crying, feeling utterly hopeless as a familiar and deep voice said:
"There's no escape......you won't ever leave..."
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
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supimjustwriting ยท 4 years ago
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Through the Garden Of Death
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A Tour Date Through Alnwick Featuring: Riddle Rosehearts, Ace Trappola, Leona Kingscholar, and Lilia Vanrouge
Authorโ€™s Note: For those who donโ€™t know, The Alnwick Garden is home to over 100 toxic, intoxicating, and narcotic plants according to their website. The plants are enclosed behind a black iron gates with matching plaques that read โ€˜These Plants Can Kill,โ€ skull and crossbones included. Theyโ€™re located in the UK and you can only enter the garden through guided tours. Youโ€™re not allowed to touch, eat, or smell any of the plants that live there. Even if you do follow these rules, thereโ€™s still a chance youโ€™ll pass out due to inhaling the toxic fumes. Of course this is just a small part of the garden like the anon mentioned! They also have rose gardens, cherry blossom trees and many other non-toxic species.
I personally always wanted to go here but enough explanation. I hope you enjoy this stroll with death.
Lilia Vanrouge
Authorโ€™s Note:
I was reading his voice lines in order to get to know his character and stumbled upon this line. Lilia no. I love you but no. โ€œIโ€™m good at identifying herbs: If you eat it and nothing happens, then itโ€™s not an herb!โ€
~
- Once he heard where you were taking him. He couldnโ€™t help but feel a tad excited. Will there be plants heโ€™s never seen before? Will they mention flora that has left this world? His personal favourite thought being how many of the โ€˜factsโ€™ ring true?
- Lilia strolls through the regular garden with a smile painted upon his lips. Each flower seems to hold a memory whether vivid or faded. It was quite bittersweet. Though being able to create new memories with you outweighed any unwanted thoughts.
- Once arriving at the poison garden. Lilia carefully listens to the guide, once in a while pulling you close to whisper in his two cents about the plant. Some โ€˜factsโ€™ he tells you are so outlandish you canโ€™t tell if theyโ€™re true or not. It became a guessing game between the two of you.
- Despite being playful throughout your whole date. He does watch out for you once youโ€™re in the poison garden, gently reminding you to wear a mask and not to get too close.ย 
โ€œThe most beautiful things can be the most dangerous. Please do take care.โ€
Riddle Rosehearts
- The idea of going to a botanical garden with you was quite charming to say the least.
- A childish glee filled his eyes when landing upon the rose garden before the two of you. All the different shapes and colours seemed disheveled at a glance but the longer you look at it, the more the scene comes together.
- He proudly points out which rose is the Queen of Heartโ€™s favourite. His hair seemingly mimicked the roses colour causing him to blend in among the bush. (You totally didnโ€™t edit a photo of him with petals surrounding his face and photoshopped him onto the bush. Nope. Not you. It was hella cute though.)
- Once nearing the poison garden. You happily chirped at the iron bars and foreboding sign. Cue confused and concerned Riddle noises. Itโ€™d be a lie to say he wasnโ€™t curious but after carefully reading over all the rules and warnings. Riddle wasnโ€™t sure if he wanted you to enter the garden. What if one of you pass out? Itโ€™s not like itโ€™s a magical garden either. He simply canโ€™t whip up a potion and make you better. Nature always has her own counters when it comes to mages.
- Reluctantly heโ€™d join you on a guided tour. His hand never letting go of yours. Riddleโ€™s grey eyes were more focused on you than on the flowers at this point. It was worth it, seeing the smile that blossomed upon your lips.
Ace Trappola
- It took a bit of convincing to get your boyfriend to agree with you to go to Alnwick. If the two of you are going out on a date. Why not do something more exciting? Your irresistible pout was what won him over in over in the end. Donโ€™t think you donโ€™t owe him anything though, heโ€™ll take kisses as payment.
- To his surprise. Instead of posing at each and every flower, you instead drag him to what reminds him of a prison courtyard. The male raised a brow upon reading โ€˜these plants can killโ€™. Did you really want to go in there?
โ€œWe already have to deal with some questionable stuff during potions. Do you really want to head into here?โ€ - So, in the end it became a study date. Not the worst thing in the world. At least he didnโ€™t have to worry about making up for not studying,
- Some of the flowers in there caused a shiver to run down his spine. There are potions that take days to prepare and this plant can cause more if not the same effects once bloomed? Why were these allowed to be shown in the public again?
- Heโ€™s reckless but not stupid. Ace keeps a close eye on you and you do the same for him. Once in a while pulling the other back if one of you gets too close. It was surprisingly fun in the end.
Leona Kingscholar
- It was a miracle that you got him up and ready to go outside. Maybe your excitement brushed off on him. Just maybe.
- The new sights and scents were refreshing. You bouncing ahead of him was tiring yet endearing. If you were lucky heโ€™d even point out some plants that grew in the Afterglow Savanna.
- His smile was wiped from his face once Leona caught a whiff of the poison garden.. The botanical garden was quite pleasant until those nauseating scents wafted around. It was too the point the lion actually herded you away from that part of the garden.
- Sitting on a bench nested near the entrance. Your poor boyfriend was pale with his head pounding. Needless to say. The two of you didnโ€™t enter the poison garden but you did enjoy the other sights once Leona felt better.
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modafinilxpills ยท 4 years ago
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Foremost Vital Data for Tapentadol Consumers ย | Tapentadol. Tapentadol side effects and reviews
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dougcyr935419 ยท 4 years ago
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Does Shining Silver Haze Contains Narcotic Qualities Or Not
There basically one strategy give up smoking weed and to get to convince yourself your life could better without this. I'm sure you already thinking that your life will be superior off without this in long term because tend to be reading this article. But what I want to convince you of is that your life often be better off without it NOW.
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supimjustwriting ยท 4 years ago
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Through The Garden of Death
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This is a repost due to Tumblr not showing this in the tags
Please read the whole ask here
Authorโ€™s Note:
For those who donโ€™t know, The Alnwick Garden is home to over 100 toxic, intoxicating, and narcotic plants according to their website. The plants are enclosed behind a black iron gates with matching plaques that read โ€˜These Plants Can Kill,โ€™ skull and crossbones included. Theyโ€™re located in the UK and you can only enter the garden through guided tours. Of course this is just a small part of the garden like the anon mentioned! They also have rose gardens, cherry blossom trees and many other non-toxic species.ย 
Youโ€™re not allowed to touch, eat, or smell any of the plants that live there. Even if you do follow these rules, thereโ€™s still a chance youโ€™ll pass out due to inhaling the toxic fumes.
I personally always wanted to go here but enough explanation. I hope you enjoy this stroll with death,
Lilia Vanrouge
Authorโ€™s Note: I was reading his voice lines in order to get his character right and stumbled upon this line. Lilia no. I love you but no. โ€œIโ€™m good at identifying herbs: If you eat it and nothing happens, then itโ€™s not an herb!โ€
~
- Once he heard where you were taking him. He couldnโ€™t help but feel a tad excited. Will there be plants heโ€™s never seen before? Will they mention flora that has left this world? His personal favourite thought being how many of the โ€˜factsโ€™ ring true?
- Lilia strolls through the regular garden with a smile painted upon his lips. Each flower seems to hold a memory whether vivid or faded. It was quite bittersweet. Though being able to create new memories with you outweighed any unwanted thoughts.
- Once arriving at the poison garden. Lilia carefully listens to the guide, once in a while pulling you close to whisper in his two cents about the plant. Some โ€˜factsโ€™ he tells you are so outlandish you canโ€™t tell if theyโ€™re true or not. It became a guessing game between the two of you.
- Despite being playful throughout your whole date. He does watch out for you once in the poison garden, gently reminding you to wear a mask and not to get too close.ย 
โ€œThe most beautiful things can be the most dangerous. Please do take care.โ€
38 notes ยท View notes
ishubhampatil09 ยท 4 years ago
Text
Drug Abuse Treatment Market Size, Trends, Shares, Insights and Forecast - 2026
Medication Abuse can be characterized as constantly, reliance of a person on any medications, which transforms into a compulsion. Liquor, tobacco, cigarettes, heroin, and cannabis are a portion of the normal, drugs which has been abused prompting drugs addictions. In ongoing past, numerous items have been dispatched in market for treatment and the board of medication misuse. Some normally utilized medication for treatment of medications misuse are Disulfiram, Acamprosate, Naltrexone, Nicotine Replacement Treatment, Methadone, and Buprenorphine.
Dispatch and endorsement of novel medications is extended to fuel market development over the estimate time frame
In 2017, Indivior PLC got the U.S. Food and Drug Administration (FDA) endorsement for SUBLOCADE (buprenorphine expanded delivery) infusion for subcutaneous use, which is demonstrated for treatment of moderate to extreme narcotic use issue. Besides, in 2016, Teva Pharmaceutical Industries Ltd. dispatched a nonexclusive rendition of CAMPRAL1 (acamprosate calcium) deferred discharge tablets, 333 mg in the U.S. market, which is shown for the treatment and upkeep of forbearance from liquor in patients with liquor reliance. In addition, in April 2018, Dr. Reddy's Laboratories got the U.S. Food and Drug Administration (FDA) endorsement to dispatch conventional adaptation of Suboxone sublingual film for all dose structures 2 mg/0.5 mg, 4 mg/1 mg, 8 mg/2 mg, and 12 mg/3 mg showed for the treatment of chronic drug use. Suboxone is a blend of Buprenorphine and Naloxone.
In 2014, British American Tobacco plc. gotten endorsement from the UK Medicines and Healthcare items administrative office for new items nicotine inhaler. This new inhaler will assist with stopping smoking propensities for dependent smokers, this new inhaler contains a similar fuel found in an asthma inhaler and gives a quick hit of nicotine through a breath-worked valve. In 2015 organization dispatched nicotine inhaler in the UK. Incessant dispatches of such novel medications in market are required to fuel the worldwide medication misuse treatment market development.
The worldwide medication misuse treatment market size was esteemed at US$ 13.4 Bn in 2017, and is relied upon to observe a CAGR of 7.8% over the estimate time frame (2018 โ€“ 2026).
Figure 1. Worldwide Drug Abuse Treatment Market Share (%), By Region, 2017
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Source: Coherent Market Insights Analysis (2017)
Reference - https://www.coherentmarketinsights.com/market-insight/drug-abuse-treatment-market-2011
Expanding predominance of medication maltreatment in key area is required to build interest for its treatment drugs
As indicated by the information distributed by Centers of Disease Control and Prevention (CDC) in 2016, more than 15 of each 100 grown-ups or 15.5% of grown-ups matured 18 years or more established smoked cigarettes in the U.S. as per a similar source, an expected 37.8 million grown-ups in the U.S. at present smoke cigarettes and in excess of 16 million individuals in U.S. are enduring with a smoking-related sickness. As indicated by the World Health Organization (WHO), in 2015, cycle 1,100 million smokers were recorded around the world, which incorporates around 33% of the worldwide populace matured 15 years. Such expanding pervasiveness of medication maltreatment in key areas is required to move interest for its treatment medications and drive worldwide medication misuse treatment market development.
Figure 2. Worldwide Drug Abuse Treatment Market Value (US$ Bn), (2017, 2022, 2026)
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Source: Coherent Market Insights Analysis (2017)
Read More - https://www.coherentmarketinsights.com/press-release/drug-abuse-treatment-market-to-surpass-us-263-bn-threshold-by-2026-1049
Central participants in the substance misuse treatment market are centered around accepting endorsement of its new medications from major administrative bodies. For example, BioCorRx Inc. built up an innovative work activity to look for endorsement of its naltrexone embed from the U.S. Food and Drug Administration (FDA) in 2016. Naltrexone embed works by delivering medication in body for a while and diminishes the longings for liquor and narcotics.
Besides, the activities taken by different associations to help individuals in forestalling substance misuse and dispatches of new medication misuse recovery are required to help the worldwide medication misuse treatment market development. For example, in 2017, Cardinal Health, Inc dispatched an Opioid Action Program to help the avoidance of medication maltreatment in Appalachia.
Talk To Analyst - https://www.coherentmarketinsights.com/insight/talk-to-analyst/2011
Central participants working in the medication misuse treatment market incorporate Cipla Limited, Glenmark Pharmaceuticals, Pfizer Inc., Mylan N.V., Odyssey Pharmaceuticals Inc., Lil' Drug Store Products Inc., Indivior Plc., Dr. Reddy's Laboratories, Teva Pharmaceutical Industries Ltd., and British American Tobacco Plc.
Buy This Research Report - https://www.coherentmarketinsights.com/insight/buy-now/2011
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Coherent Market Insights is a global market intelligence and consulting organization focused on assisting our plethora of clients achieve transformational growth by helping them make critical business decisions.
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tramadolcodpills ยท 4 years ago
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How to order tapentadol online without prescription for pain relief?
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Tapentadol tablets are widely used by the doctors to treat moderate to severe pain (pain that starts suddenly, has a specific cause, and is expected to go away when the cause of the pain is cured). Tapentadol long-acting tablets are used to treat severe nervous pain (pain caused by nerve damage) in diabetics.
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genrxonline ยท 4 years ago
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hgfstreamchats ยท 7 years ago
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Christmas Eve Eve Stream
Welcome to the 'highglossfinish' room. Knock Out: To you too! blythe1: Hey all Knock Out: Hello there! thenightetc: Hi! thenightetc: Don't know why chat wasn't working there Knock Out: Livestream hates Christmas, clearly. thenightetc: Apparently! blythe1: Livestream will be visited by three ghosts tonight to rediscover its love for Xmas. blythe1: I've lived in worse towns. thenightetc: ...Oh, right, and you put the wrong link in the post. thenightetc: Left out the "original." at the beginning Knock Out: Let me fix that! Knock Out: There we are. Thank you for letting me know! Shockbox: Ah. Shockbox: Of course. Shockbox: Good evening, folks. thenightetc: Good evening. blythe1: Hi Shockbox Knock Out: Good evening! blythe1: We need a robot who looks good in red with an ever happy smile to be Santa, Knock Out do you know someone like that? Knock Out: I may know a mech. Knock Out: But I demand my own Christmas special. blythe1: If only.
thenightetc: They didn't think this through very far. Shockbox: The height of comedy. Shockbox: Hm. If I recall correctly, I only saw the very end of this episode last year. Knock Out: There's a reason it's a yearly staple! Shockbox: I think I understand that now. Shockbox: Here we are, I recall this. thenightetc: I do like that ending. blythe1: I like a show with a nice clear moral Shockbox: It's decent. Shockbox: So, what's this about a calf? Knock Out: Also a tradition. blythe1: I;m curious about that cockatiel thing there! thenightetc: Oh no. Knock Out: And of course, the drugged children. thenightetc: Honestly, days should all be silent, too. blythe1: I kinda want to ask those kids to blink twice if they need help. Knock Out: When Breakdown and I first heard it, that's what we thought was she was saying. blythe1: This is GENIUS!!!! thenightetc: Good content. Knock Out: Birds certainly are...something. Shockbox: //Clasping hands together. Shockbox: Agreed. Shockbox: Ah, it briefly sang jingle bells. Clearly this is a christmas video. Shockbox: Very relevant to this stream. Knock Out: 100 percent. blythe1: Thank you KO! Knock Out: Of course! Shockbox: Oh, this looks vintage. Shockbox: Early 2000's? Knock Out: 1997, apparently. Shockbox: Close enough. blythe1: It has the voice of Blanche from the Golden Girls in it. That can't be recent. blythe1: Sounds like he ought to have wished for a newer truck. thenightetc: Oh, great. Knock Out: Grandpa's consideration for his disabled grandson's comfort is something to behold. Knock Out: Just bring the barn children along so they can snuff out matches on him between songs. Shockbox: //A gentle sigh. thenightetc: I know, right? Knock Out: They look like siblings. Shockbox: How is that canine waving with its ear? Knock Out: Something demonic. Shockbox: I am under the impression that all of the fauna presented are not of earthly origin. thenightetc: Don't nail boards to your child. Shockbox: ...I /must/ wonder what Soundwave would think of this..."Representation". thenightetc: Whooops, I guess Aunt Agnes has been drinking too much eggnog. blythe1: Finally a character I can empathise with, where is that 2nd bottle of wine. thenightetc: The hell? blythe1: Oh, wait. Nope, Can't empathise with a childkidnapper. Although I can empathise with her being a pennypincher. Knock Out: She should have had more eggnog. She wouldn't care so much about childnapping. blythe1: Now that is a message I can get onboard with, KO blythe1: Eggnog for everyone. Shockbox: The barn burnt down, but luckily, every animal in it survived. Shockbox: Those are not ears, I'm thoroughly convinced they're some type of arm. blythe1: Oh. Did anyone read about that fire at London Zoo this morning? It didn't have as happy an ending, they lost an aardvrk and 4 meerkats. It was so sad. thenightetc: Oh no! Knock Out: Well, that's depressing. thenightetc: ...This just took a turn for the surreal Shockbox: Hm. Knock Out: Why couldn't these animals have died in a fire instead? Shockbox: I'm sure this old mythical man has plenty of time to stand around to talk on christmas eve. thenightetc: ...What. Shockbox: The horse is flirting with that human. blythe1: There was once a guest on Jerry SPringer who claimed his horse was flirting with him Knock Out: Of course he did. Shockbox: Was he one of those..."Bronies"? blythe1: This was pre-Brony era. But he did marry his horse live on air and kissed it. Shockbox: I...See... Shockbox: I see Blaster landed himself a voice acting gig. blythe1: Well that cockerel just volunteered to be Sunday Dinner. blythe1: Just a PSA, kids. Never Drink and Drive. thenightetc: oh boy Shockbox: This family is a mess. Shockbox: ...You can't gift the calf, she's sapient. thenightetc: I think this is one of those uncomfortable universes where they're not aware of that. thenightetc: After all, it's a "secret" that they can talk Shockbox: I suppose Santa of all people wouldn't be against slavery. blythe1: Seems like the drunk aunt might have a point? thenightetc: Well, NOW there's no passing it off. Shockbox: ...The pig just spoke in front of all of them. Knock Out: He goes into the house and writes a small novel about it. Shockbox: He's shown to be literate, after all. blythe1: I feel like this raises many questions, especially about the food system in this universe. thenightetc: You know they're raising that pig to eat him. Shockbox: Too many 'talking animal" universes have this problem. blythe1: Again, I feel like drunk aunt Agnes might have a point. blythe1: again blythe1: I mean, nothing wrong with a second opinion from a specialist. thenightetc: AT some point they're probably going to be shown eating meat. thenightetc: And nobody will comment. blythe1: We've already seen them leaving milk out for Santa Knock Out: That's probably why grandpa impregnated Annabelle's mother. Knock Out: ...Had her impregnated. Shockbox: .....Knock Out.... Knock Out: It's out there. Now we all have to live with it. Shockbox: Primus. blythe1: Lives on a farm, can't identify a cow. Shockbox: She's two days old, maybe back off? Knock Out: You're all talking because a fat man sprayed you with magic dust. Shut up. Shockbox: Oh here we go. Shockbox: Obligatory musical number. blythe1: This reminds me entirely too much of the song sequence from Watership Down. Knock Out: Dear Unicron, you're right. caffienatedconfetti: henlo Shockbox: Greetings. blythe1: Hi caffienatedconfetti: what are we watchin Knock Out: Annabelle's Wish. Shockbox: Deranged Calf Show caffienatedconfetti: is it any good? Knock Out: No. thenightetc: Uhhhh Knock Out: Can't fences be mended? thenightetc: This doesn't seem legal blythe1: I feel like that should require a court order. caffienatedconfetti: that is definitely illegal Shockbox: This shouldn't be legal at all. Shockbox: It's a few pieces of wood. blythe1: Not to mention even I could have fixed that fence. All it needs is wood and nails. caffienatedconfetti: heck i coulda fixed it and i don't know anythin about fences blythe1: He could get those from dissassembling one of the porch benches Shockbox: "You touched my flimsy pieces of wood? Well, I guess I'll just take one of your food sources without your consent." caffienatedconfetti: NO caffienatedconfetti: NO caffienatedconfetti: NOT THIS thenightetc: ...A calf is definitely more valuable than a music box caffienatedconfetti: ANYTHING BUT THIS caffienatedconfetti: COUNTRY MUSICCCCCC Shockbox: Song count: 2 caffienatedconfetti: NOOOOO caffienatedconfetti: auuguuhu Shockbox: I would average the song quality to be, on average, 2.5/10 caffienatedconfetti: i hate country musc so, so much Shockbox: You can mute the tab. caffienatedconfetti: thank you caffienatedconfetti: tell me when it stops Shockbox: Will do. blythe1: That calf doesn't seem to be growing, they should call a vet blythe1: Some sort of pituitory problem there, surely. Knock Out: The last one was nice. They doubled their mileage by applying it to sick human children, apparently. caffienatedconfetti: she's secretly an alien Knock Out: The intergalactic community doesn't want her. Shockbox: Finally, the song is over. blythe1: Song's done caffienatedconfetti: thanks! caffienatedconfetti: my ears didn't need that cancer Shockbox: It seemed to go on much longer than it wanted to. Shockbox: *needed Shockbox: ...Sign language exists. Shockbox: Nonverbal forms of communication exist. thenightetc: Now trample them. caffienatedconfetti: ah, the old "bullies don't like girls" caffienatedconfetti: how original Knock Out: It doesn't seem like a sign language kind of town. Shockbox: Sigh. blythe1: I think they only know one hand sign there. caffienatedconfetti: "hhneh" Knock Out: Sign language, court orders, doctors... thenightetc: Hhahaha caffienatedconfetti: what's this? caffienatedconfetti: who is that screechy blonde witch??? Knock Out: Drunk Aunt Agnes. caffienatedconfetti: why does she want him?? blythe1: Drunk aunt agnes, who is unpleasant but has been in the right. thenightetc: I'm not really clear on that, to be honest. blythe1: He has been in danger on the farm, he does need a second opinion, eggnog is a basic human right! caffienatedconfetti: the animals are agents of chaos Shockbox: She apparently just didn't want to celebrate christmas alone. Shockbox: That is her entire motivation. caffienatedconfetti: lord caffienatedconfetti: end me caffienatedconfetti: so why can't the kid talk...??? thenightetc: There was a fire Shockbox: He was in a barn that caught on fire and....Was presumably traumatized? blythe1: From context, smoke inhalation has damaged his vocal chords. I think thenightetc: and presumably he inhaled some smoke and damaged his lungs or something Shockbox: Or, perhaps, the smoke destroyed his vocal chords. blythe1: SInce he's only been seen by the old country GP, it could be anything. caffienatedconfetti: santa is a WITCH thenightetc: Do they not hear that rooster Shockbox: Yes. Yes he is. blythe1: Cocaine? caffienatedconfetti: ah, the magic of hard narcotics thenightetc: But the magic dust only lasts for a day. Shockbox: Way to get the child's hopes up. blythe1: I'm not sure that is how child removal orders work? blythe1: I feel I may be being too mean for this movie. caffienatedconfetti: great caffienatedconfetti: their children will be HIDEOUS thenightetc: Really. Shockbox: Why has her face not changed at all. thenightetc: Oh, I guess it didn't just last the one day. Shockbox: That is not the face of an adult cow. caffienatedconfetti: the face of pain caffienatedconfetti: and cheap animation Knock Out: Those antlers are probably weighing down her old neck. caffienatedconfetti: "SANTA COMES, TO FULFILL YOUR DARKESTS DREAMS" blythe1: Is Santa also the Grim Reaper? thenightetc: ....Maybe? Shockbox: It's probable, in this universe. Knock Out: You can't prove he isn't. Shockbox: *There was only green under his jacket.* Shockbox: If you stare underneath the old man's jacket, you stare into the void. caffienatedconfetti: ...but females don't have antlers??? thenightetc: It's a christmas miracle! Knock Out: They actually do! blythe1: I think it depends on the deer species caffienatedconfetti: huh Shockbox: You're all missing the obvious conclusion. caffienatedconfetti: female reindeer have antlers? Shockbox: They're transgender. Shockbox: Case closed. caffienatedconfetti: that was my first thought, actually blythe1: I just want to say, I should have drunk far more wine before watching this one. Knock Out: According to your datanet, female reindeer have antlers. And during your holiday season, the males don't. caffienatedconfetti: i left by accident caffienatedconfetti: oh my god thenightetc: So are all of Santa's reindeer animals he rescued(?) and magically changed the species of? caffienatedconfetti: ....'santa and the ice cream bunny'? Shockbox: It's possible, according to that movie. caffienatedconfetti: oh my god, is this MYSTERY SCIENCE THEATER??? Knock Out: It's rifftrax. We used up our MST3K Christmas quota the last two years. caffienatedconfetti: lel Shockbox: Mmmm. Shockbox: I suppose we won't have much to say, they'll do all the riffing for us. thenightetc: If Santa *weren't* also Death then why wait until she was apparently dying to show up. caffienatedconfetti: what are they singing even? blythe1: The Christmas palm tree? blythe1: Global warming is really taking its toll. Shockbox: And then...Santa ran into Amelia Earhart. blythe1: And ate her? Shockbox: No, no, he watched her get eaten by crabs. Shockbox: "It's not Christmas, therefore helping you is outside of ย my jurisdiction." blythe1: Santa stuck in Florida? Is this an I Dream of Jeannie crossover movie? Shockbox: Is...This some kind of opera? caffienatedconfetti: i think it is blythe1: Santa is tripping caffienatedconfetti: judging by the hand-flailing Shockbox: He's very bored with his situation. caffienatedconfetti: i love these guys caffienatedconfetti: DOG caffienatedconfetti: oh my god caffienatedconfetti: they know what we're thinking Shockbox: Is Santa casting some sort of spell on the humans of the world? thenightetc: Maybe? blythe1: I'm thinking, "Jimmy Saville's home videos" right now. caffienatedconfetti: THEY KNOW caffienatedconfetti: SANTA CALLS thenightetc: I guess the Time Stop wore off? caffienatedconfetti: KAZOOS caffienatedconfetti: KAZOOOOOOOOOOS Shockbox: He's just summoning all of these random children to this unspecified island? caffienatedconfetti: THE KAZOOS thenightetc: Santa is the Pretend Spirit Knock Out: That can only end well. Knock Out: NO. caffienatedconfetti: i swear to god they're psychic thenightetc: Search your feelings. ย You know it to be true. Shockbox: This is directed and written in a manner that is uncomfortably close to modern productions that are /meant/ to be vaguely disconcerting or frightening. caffienatedconfetti: i love mystery science theater SO GODDAMN MUCH thenightetc: Is that a racoon thenightetc: it IS a racoon caffienatedconfetti: i can't stop laughing caffienatedconfetti: aaaaand i just snorted my seltzer blythe1: Be careful with raccoons, one attacked a baby in philedelphia a couple of days ago Shockbox: Good job, CC. blythe1: got in the house and mauled a four month old caffienatedconfetti: there is exactly one black child thenightetc: And they all immediately kneel down Shockbox: Ah, Representation. caffienatedconfetti: BOW TO YOUR LORD blythe1: Santa endorses child labour thenightetc: Is he going to turn them into reindeer and make them pull him around Cardinal: Hello! Knock Out: Cardinal! Hello! blythe1: Hi Cardinal caffienatedconfetti: henlo, we're watching 'santa and the ice cream bunny' Cardinal: wh Cardinal: what is this caffienatedconfetti: 'santa and the ice cream bunny' Shockbox: A masterpiece. caffienatedconfetti: DOG caffienatedconfetti: cut dog, good dog Shockbox: A horrible masterpiece. caffienatedconfetti: *cute caffienatedconfetti: just let me pet the dog Cardinal: what is this caffienatedconfetti: 'santa and the ice cream bunny' Shockbox: A masterpiece. caffienatedconfetti: DOG caffienatedconfetti: cut dog, good dog Shockbox: A horrible masterpiece. caffienatedconfetti: *cute caffienatedconfetti: just let me pet the dog blythe1: Did the spell wear off? caffienatedconfetti: the pied piper of the north pole caffienatedconfetti: ....what caffienatedconfetti: what caffienatedconfetti: i dont thenightetc: Where did she get a gorilla caffienatedconfetti: what blythe1: It is the ghost of harambe Shockbox: Ah, I see, she recruited bigfoot. caffienatedconfetti: i don't Cardinal: . . . caffienatedconfetti: this is oddly sexual caffienatedconfetti: it's the grunting okay Shockbox: ...He just needs his sleigh out of the snow, doesn't he? Shockbox: Er. Sand. Cardinal: Wouldn't it help if he . . . got out of the sleigh. Shockbox: Why doesn't he *get out of it* before asking people to move it. thenightetc: Yes, you'd think he could pull it out himself. Shockbox: //Snort. thenightetc: It doesn't look that heavy. blythe1: It does not look like a heavily built vehicle, Santa himself must weigh more than the sleigh caffienatedconfetti: angry pig thenightetc: Exactly. blythe1: Oooh, the Christmas ham has arrived. thenightetc: Maybe he's stuck. thenightetc: Or just very stupid. caffienatedconfetti: wait why would a pig work better than a mule and a m man in a gorrilla suit??? thenightetc: Oh so he CAN get out! Knock Out: Dear sweet Unicron. caffienatedconfetti: those poor animals Shockbox: There he goes! It's not that hard. caffienatedconfetti: sobbing blythe1: I'm guessing this movie did not get the "no animals were harmed" award thenightetc: Were they even trained animals? blythe1: trained better than the film makers caffienatedconfetti: the raaccon and the dog were obviously somewhat trianed blythe1: Oh it is the cast of the last movie caffienatedconfetti: ohhh, that poor horse! their hooves aren't built for sand!! caffienatedconfetti: poor baby caffienatedconfetti: stop hitting the horse!! blythe1: Yes, get out! caffienatedconfetti: STOP caffienatedconfetti: THAT POOR HRSE IS SO CONFUZZLED thenightetc: The horse just seems confused. blythe1: These kids are obviously within walking distance of a populated area. Go walk there and phone for a taxi. blythe1: It isn't even slightly buried. thenightetc: Is he. ย Still trying to sit in the sleigh and dig it out a tthe same time. thenightetc: Does anyone else find it strange that it's just him in the sleigh, and no presents? Knock Out: He's not Santa at all, just a bad man. blythe1: Oh god, singing. Cardinal: . . . Knock Out: With filthy pants. Shockbox: ...Well, at least we went for a good few minutes without having to endure this singing. Cardinal: Didn't Rudolph establish that Santa is a bad man? caffienatedconfetti: yes caffienatedconfetti: we're in hell blythe1: Either in hell, or on a hell of an acid trip Shockbox: Is....Is this really happening? thenightetc: I'm so confused. Shockbox: Okay. Cardinal: WHY caffienatedconfetti: we're dead and in hell caffienatedconfetti: *get sshot in spanish* Shockbox: And *then* the protagonist in this movie will start talking about a protagonist from a *different* story. caffienatedconfetti: i can't stop laughingggg Knock Out: I'm wheezing. thenightetc: Why is the ceiling in there so low blythe1: Remember when asking for children from witches and the fey always be specific in your wants. They love to screw you over with exact words. caffienatedconfetti: i love these guyss blythe1: The ceiling is so low because she bought it cheap from Yoda's estate caffienatedconfetti: "buy cheap, this house, you will" thenightetc: pffff thenightetc: They were really desperate to fill out the running time, huh. blythe1: duck into a swan, an anthem for the CRISPR generation Shockbox: Apparently. caffienatedconfetti: WHEEZE caffienatedconfetti: ....that looks like a boy wearing a wig caffienatedconfetti: "you and i are going to have fun together" blythe1: That is some bad CSO, even for this movie thenightetc: Uhhhhhhhhh caffienatedconfetti: is that a man in a frog suit caffienatedconfetti: WHAT HAPPENED TO SANTA caffienatedconfetti: i think marriage is a consent thing??? blythe1: WTF? thenightetc: Are they supposed to be... insects? thenightetc: I mean, the extra..... limbs blythe1: Giant shrooms, I think I've found the explanation for this movie thenightetc: Is her mother even looking for her? thenightetc: She can't be too far away blythe1: the snow in old movies was actually asbestos. Not even joking about that, they used to use asbestos for fake snow thenightetc: Well, that's cheery caffienatedconfetti: assbestos thenightetc: yikes caffienatedconfetti: why this Shockbox: ...How much longer. Shockbox: How much longer is this film. blythe1: It never ends caffienatedconfetti: it will last for eternity caffienatedconfetti: this is hell after all blythe1: It lasts forever, ahahahaha thenightetc: This is what happens when you get on Santa's naughty list! ย Take note. blythe1: Damn, I didn't realise just how naughty I must have been this year thenightetc: errrrr blythe1: A saga of child trading and forced marriages, such a classic tale for Santa to tell kids. caffienatedconfetti: wait caffienatedconfetti: I JUST REALIZED SOMETHING caffienatedconfetti: THAT MOLE MAN IS WEARING THE BODY PART OF THE GORILLA SUIT thenightetc: Oh my god. ย Yeah, plus a coat Knock Out: By the core, it is! thenightetc: I'm so uncomfortable with how they keep saying how young she is and how she's a child. thenightetc: "you're such a beautiful child! ย marry me" thenightetc: :| Cardinal: uhhhh caffienatedconfetti: jesus thenightetc: see? blythe1: A day, but it feels soooooooooooo much longer. thenightetc: "but I AM rich" caffienatedconfetti: it puts the lotion on its skin or else it gets the hose again thenightetc: "he'll die pretty soon and then you'll be a rich widow!" Knock Out: This couldn't have less to do with Christmas. caffienatedconfetti: i don't know where i am thenightetc: Please tell me the bird's not going to try to marry her, too blythe1: I think I actually miss drunk Santa at thispoint caffienatedconfetti: yes Knock Out: AHHHH! blythe1: She is not a human being, she grew fully formed from a seed caffienatedconfetti: plant hybrid caffienatedconfetti: OH MY LORD blythe1: I can't imagine there could be a worse fate that being in thiis movie blythe1: Winter is coming! Shockbox: So...When will this have anything to do with an ice cream bunny? blythe1: It melted Shockbox: At the beginning? Cardinal: . . . . blythe1: Another forced ย marriage? blythe1: I seriously question the message this movie is pushing thenightetc: So... what about her mother Thebes: Oh man I'm late--what fresh nonsense is this? blythe1: I hope those flower buds they are standing in are the same as those from little shop of horrors thenightetc: So, they absolutely just spliced another entire story in, didn' tthey blythe1: back at Santa's cult thenightetc: Credits and all thenightetc: Er, movie blythe1: Yes, Santa is dead, we're freeeeeeeee Cardinal: . . . caffienatedconfetti: am i on crack thenightetc: No, this is really happening Thebes: This feels like a festive fever dream blythe1: THE SIREN MEANS THE NUKES ARE COMING, RIGHT? blythe1: And they just ran over the camera man, which must be a relief for him caffienatedconfetti: screaming blythe1: You know the worst apart about this? caffienatedconfetti: i am screaming caffienatedconfetti: the screaming never ends thenightetc: The dog turning to look at the camera blythe1: I hear Michael Bay has signed on for a remake. Thebes: I feel like that's untrue but... cite your sources blythe1: He's signed on for a reboot for everything else. caffienatedconfetti: eeend me caffienatedconfetti: hwy tjhs caffienatedconfetti: whys blythe1: Just get him on the car and drive to the closing credits, already. thenightetc: The dog seems kind of freaked out at the bunny, there. caffienatedconfetti: please kill mee blythe1: Just for the record, that is not the right way to crank start a car blythe1: if it kicks back then it can break your arm. thenightetc: Look at that kid struggling to keep the dog from running off. thenightetc: ....So could he have done that at any time, or Thebes: I... I don't know blythe1: Is it over, truly? caffienatedconfetti: thank god thenightetc: That description caffienatedconfetti: i am freed Knock Out: It's over. Dear sweet Unicron, it's over. Knock Out: But will we ever be free? That's the question. blythe1: I'll be good next year, promise. Knock Out: I promise nothing. thenightetc: That was really.... something. blythe1: I have to look up that movie's IMDB page to see if anyone in it ever worked again Knock Out: Wasn't it just? Knock Out: Thank you all for stopping by and enduring it! thenightetc: Thank you for infli--*sharing* it with us. blythe1: Wouldn't have missed it for the world, KO. Thank you. blythe1: I love your Christmas livestreams. THey are always great. caffienatedconfetti: goood night Thebes: I only caught the end, but even that was...amazing, shall we say. thank you! Knock Out: You're all very welcome! caffienatedconfetti: it was endless pain caffienatedconfetti: and trauma thenightetc: That description caffienatedconfetti: i am freed Knock Out: It's over. Dear sweet Unicron, it's over. Knock Out: But will we ever be free? That's the question. blythe1: I'll be good next year, promise. Knock Out: I promise nothing. thenightetc: That was really.... something. blythe1: I have to look up that movie's IMDB page to see if anyone in it ever worked again Knock Out: Wasn't it just? Knock Out: Thank you all for stopping by and enduring it! thenightetc: Thank you for infli--*sharing* it with us. blythe1: Wouldn't have missed it for the world, KO. Thank you. blythe1: I love your Christmas livestreams. THey are always great. caffienatedconfetti: goood night Thebes: I only caught the end, but even that was...amazing, shall we say. thank you! Knock Out: You're all very welcome! caffienatedconfetti: it was endless pain caffienatedconfetti: and trauma caffienatedconfetti: it will be in my nightmares blythe1: Merry Christmas, everybody. caffienatedconfetti: mebby chruistmun Knock Out: Merry Christmas, happy holidays, may Santa's filthy pants keep clear of your dreams! thenightetc: Same to you! ย And goodnight. blythe1: Since it is now 5am in my timezone, I will bid you all good night. See you all next year. Thebes: good night!
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juniperpublishersjcmah ยท 5 years ago
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Comparison of Analgesic Efficacy of Paracetamol and Pethidine for Pain Relief in Active Labor
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For more articles please click on Journal of Complementary Medicine & Alternative Healthcare
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Background and Objective: Using pain-relieving drugs during labor is now part of standard care in many countries throughout the world. There are many methods for reducing pain in labor time and each method has its own risks and benefits. The aim of this study was to assess the efficacy of pethidine versus paracetamol as an analgesic during labor in pregnant women. Methods: In this clinical trial study, 100 women expected to have a natural childbirth were observed and then randomly allocated two groups. The first groups receive paracetamol and the second group receives pethidine. The intensity of labor pain experienced by the subjects and the outcome of delivery were collected by a checklist. Results: There was a significant difference between the average pain score in paracetamol and pethidine groups in 30 minutes after intervention, but there was not a significant difference between the severity of the pain in two groups before intervention and 10 and 60min after intervention. No significant differences were seen regarding duration and interval of uterine contractions, neonatal complications, first minute Apgar score and side effects of used drugs between the two studied groups. There was a significant difference between the average of fifth minute Apgar score and mother SBP and RR after intervention between two groups. Conclusions: Use of paracetamol reduces pain more than pethidine within 30 minutes after intervention
Keywords: Pethidine; Labor pain; Paracetamol; Ardabil
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Introduction
Today pain is one of the major causes that caused pregnant women donโ€™t tend to have normal delivery. Pain relief is a major part of the science of midwifery. Severe labor pain is associated with psychological and physiological complications on mother and fetus. Labor pain and its prolonged duration are the most important factors in encouraging pregnant women to cesarean delivery which not only requires more specialized facilities and higher costs, it also causes more maternal complications. Therefore, reducing labor pain and its duration is one of the major steps in reducing misplaced cesarean delivery [1-2]. Labor pain is one of the most severe pain experienced by women during their lifetime [3]. This pain is especially severe and longer in primiparous women [4]. The cause of labor pain is cervical stretching during dilatation and ischemia of the uterine wall during lactate production [3]. Pain is an unpleasant feeling that medical science has always been trying to eliminate or reduce it [6]. But, the severity and extent of pain tolerance vary in individuals and under different conditions [7-8]. Based on studies, 77% of primiparous women described labor pain as severe and intolerable [9]. Labor pain can have many adverse effects on delivery process, maternal and fetal status [10]. Severe labor pain may cause long-term imbalances that disturb the mental health of the mother and has a negative effect on the relationship between mother and baby in the first days of life which was very important [11]. Unwanted side effects due to labor pain in the fetus including late loss of fetal heart rate following the reduction of maternal arterial oxygen pressure, decreased uterine patchy blood flow due to severe uterine contraction during labor pain and fetal acidosis, which occurs in some cases [12]. According to studies, today most of women want a form of analgesia at the time of delivery [13]. For more reasons there is no way to relieve labor pain in Iran and so evaluation cheap and safe methods in this field is necessary. Various methods have been proposed for the relief of labor pain, among which non-pharmaceutical methods can be mentioned which their most important advantage is that they are uncomplicated and that their greatest defect is low effect [1]. Nonpharmacological methods included physiological delivery, delivery in water, maternal delivery in the presence of the spouse, relaxation, hypnosis, aromatic therapy and electrical stimulation. But due to the convenience and the most commonly used pharmaceutical methods, includes epidural anesthesia, spinal anesthesia, injection of sedative and opiate drugs and the use of gases such as antonox have been used for the relief of labor pain.
Today there are many methods and medications that reduce or reduce the severity of labor pain [14]. These methods are divided into four groups of psychological methods, pharmacological methods, local anesthetics and inhalation anesthetics [15]. It seems pethidine can accelerate labor by reducing maternal concentrations of catecholamines in some patients [16-17]. Pethidine is a narcotic drug that is produced by the industrial method and used to treat moderate to severe pain. In the twentieth century, pethidine was one of the most popular opioids both for acute and chronic pain. This drug in the United States is known with name meperidine [18]. Paracetamol (acetaminophen, N-acetyl-P-aminophenol) is a non-opioid analgesic that was marketed in 2002 as an intravenous infusion vial called Perforlgan. Paracetamol is an effective and safe drug with known analgesic effects, which has fewer side effects than meperidine [19]. This drug is available in Iran with the apoutel brand name in the form of 1000mg vials. The onset of the analgesic effect is 5 to 10 minutes and the maximum effect time is one hour and the duration of the effect is 6-8 hours [20]. Paracetamol is a good remedy for mild and severe pain [21-22]. Some studies have found that analgesic effects of paracetamol in reducing pain are better than meperidine [23]. Considering the increase in cesarean section rate and the promotion of normal delivery, this study aimed to compare the efficacy of paracetamol and pethidine in reducing labor pain.
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Methods
This was a randomized double blind study (Randomized clinical trial) that has been done on 100 pregnant women in the first and second parity referred to the Ardabil Alavi hospital in the active phase of labor. This study was double blind and the division of patients and injections was done by blinded persons. In this study among pregnant women who were referred to Alavi hospital in Ardabil 100 pregnant women were selected and they were randomly to groups A and B. Group A (50 cases) was injected with intravenous paracetamol at a dose of 1g and placebo and group B (50 cases) received intramuscular injection of pethidine 50mg and placebo intravenous injection. Pregnant women with singleton (37-41 weeks)-start of active phase of labor- Cephalic presentation-no fever or serious systemic illness-lack of fetal distress-lack of meconium-the lack of coagulation disorders were included in the study. Patients underwent pulsed oximetry and continuous monitoring of FHR. The checklist included age, weight, obstetric records of the pregnant mother, type of analgesia, fetal heart rate, active phase of labor, duration and intervals of uterine contractions, Apgar score in the first and fifth minutes, pain scores before and after analgesia and complications for women have been completed. Significant symptoms of the patients (blood pressure, heart rate and respiratory rate before and after pain) recorded and pain scores based on VAS were measured in minutes 10, 30 and 60. Pregnant women with disorder in fetus FHR, lack of progress in delivery, macrosomi, vaginal delivery and response to these drugs were excluded from the study. This study was approved by the Universityโ€™s Ethics Committee with the IR.ARUMS. REC.1396.202 number and registered in the Iran clinical trial database by code IRCT20150808023559N17. The collected data were analyzed using descriptive statistical methods such as tables, figures and statistical indices as average and standard deviations and statistical analytical methods in the form of various statistical tests to compare the relationship between quantitative and qualitative variables in the spss version 19. The p<0.05 was considered significant.
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Results
The average age of patients in the paracetamol group was 23.44ยฑ7.73 and in the pethidine, group was 24.98ยฑ5.15 and the difference wasnโ€™t significant. Most of women were in age group 21-30 in both groups. The mean of gestational age in paracetamol group was 38.8ยฑ2.92 and in pethidine group was 38.7ยฑ1.3 weeks and there was no significant difference between the two groups. The average score of pain in the patients in the paracetamol group was 7.68ยฑ1. 56 and in the pethidine, group was 7.38ยฑ1.97 and there was no significant difference between the two groups before the intervention
The average of pain intensity 10 minutes after the onset of the intervention in the group receiving paracetamol was 6.64 and, in the pethidine, group was 6.4 and there was no significant difference between the two groups Table 1.
The mean of uterine antractions after using drug compare to before using drug in paracetamol group was 4.36ยฑ1.12 and in pethidine group was 4.04ยฑ0.98 and the difference wasnโ€™t significant. The mean of duration and distance of uterine antractions after using drug in compare to before drug use wasnโ€™t significant between two groups Table 2.
In study the side-effects of used drug it was leveled that except the nausea, vomiting and headache which was lower in the paracetamol group than in the pethidine group there was no significant difference between the two groups in other side-effects. The incidence of complications in the pethidine group with 7 cases was higher than paracetamol group with 4 cases Table 3. Base on the findings of the study, the first- and fifth-minute neonate Apgar score showed that the majority of newborns had fifth upgar score above 9. Apgar score was higher in the paracetamol group than pethidine group and there was no significant difference between two groups in the first minute but in the fifth minute this difference was significant Table 4.
The number of heart rate of the fetus in the paracetamol group was 140.6ยฑ4.13 and in the pethidine group was 140.44ยฑ56.4 and there was no significant difference between the two groups. The mean of systolic blood pressure and maternal respiratory rate in the treatment groups were statistically significant in the post intervention period but there was no significant difference in heart rate and diastolic blood pressure Table 5.
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Discussion
The results of this study showed that the degree of pain reduction based on VAS was lower in the drug receiving groups after administration of the drug. The degree of pain reduction in the group receiving paracetamol 30 minutes after receiving drug was significantly less than pethidine group. But, over time with the absorption of pethidine the average of the numerical scale was not statistically significant for 60 minutes after intervention in the treatment groups. Allameh in a study that evaluated the effects of pethidine during delivery concluded that pain score 30 minutes after intervention was 7.8 in the control group and 6.87 in the treatment group [24]. In this study this number was 5.34 which was lower than Allameh study, stated that pethidine has the greatest effect on end stage delivery (Cervical dilatation is more than 3 to 7cm) and this would also have the least effect on maternal and fetal health [25]. In the study it was concluded that paracetamol leads to a reduction in pain score in patients [19]. In a study on patients with renal pain intravenous paracetamol was a safe and effective drug for relieving pain in patients with renal pain which could produce an analgesic effect without significant complications. Also, the results showed that paracetamol has a higher efficacy and fewer side effects than tramadol in reducing pain in patients with renal pain [26]. In a study comparing paracetamol and morphine to postoperative analgesia it was concluded that paracetamol can be used as an alternative to morphine to induce analgesia after surgery with moderate pain. Although the researchers noted that morphine produced a better short-term analgesic effect and finally the effect of paracetamol remains longer [27]. In the study of Abdollahi paracetamol produced a better analgesic effect than pethidine which is consistent with our study [28]. It seems pethidine in some patients may reduce the maternal concentration of catecholamines in the bloodstream which can accelerate the delivery [17].
But there was no significant difference between the two groups in terms of duration and contractions. The average systolic blood pressure and maternal respiratory rate after drug use were significantly different between the two groups. But the average of mother diastolic blood pressure and heart rate after drug were not significantly different between the two groups. Findings of the study on the first and fifth minute neonatal apgar showed that the majority of newborns with the first minute Apgar score above the eight and fifth grade upgrades were above nine and there was no statistically significant difference between the two groups in the first minute after delivery but the difference was statistically significant in the Apgar score in 5th minute and in the paracetamol group was more . Apgar score was higher than 8 in minutes 1 and 5 which is in line with the results of this study [28]. There was no significant difference in terms of uterine contractions and the interval between them after drug use between the two groups. In Johnterโ€™s research using internal monitoring it was found that pethidine increases intrauterine pressure and the severity of uterine contractions while the duration and distance of the contractions do not change [29]. Kamyabi donโ€™t observed different in the number and intervals of uterine contractions in the pethidine and control group which was in line with the results of the present study [30]. Studies have shown that taking pethidine at doses less than 100mg does not cause fetal complications during delivery and if the baby is born within one to four hours after taking pethidine, the probability of a babyโ€™s depression is low [17]. In the pethidine at dose 75mg did not have any side effects for the mother and no difference were found in blood pressure, heart rate, maternal respiratory rate and heart rate of the fetus before and after the injection [30]. Neonates born in both groups had a good Apgar score and none of the babies needed naloxone administration and resuscitation [30]. The results of this clinical trial were similar to the study of Mesadegh zadeh and Hontosh zadeh [31-32]. In the study there was no difference between the two groups of paracetamol and pethidine in terms of drug side effects [28] which was in line with the results of this study.
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Conclusion
Using paracetamol reduces pain more than petidine within 30 minutes after taking the drug. Using paracetamol has less side effects on mothers than pethidine. Neonates born to mothers of parestamol group had higher Apgar scores compared to those born to mothers of pethidine group.
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meganmariedeighan ยท 5 years ago
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Is CBD Liquid legally available in Germany?
ingredients Much more important than taste aspects are the ingredients used to assess the quality. A top product is characterized by the use of high quality ingredients. Equally important is that the CBD Liquid has undergone quality control and has a corresponding test certificate. CBD e-liquids usually consist of five ingredients: in addition to the CBD, they also contain propylene glycol, known as E 1520, glycerine, known as E 422, natural flavors and distilled water. Nicotine-containing liquids also contain nicotine. The latter is rather to classify as negative in terms of health. The aromas are usually taken deeper moves. Nicotine can cause all the more fatal health damage.
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Amount of CBD included
An important quality criterion is the amount of contained CBD. Many of the CBD E-Liquids available today contain an amount of 100 milligrams of carrier compound composed as indicated above. However, the CBD content can be very different. The CBD dosages range from 50 milligrams to 1,000 milligrams. Beginners of the Vapen should start with a low CBD dose, because the CBD is absorbed very quickly during the vaping, and has a strong effect even at relatively low doses. In addition, at higher doses, more side effects are to be expected. The organism needs some time to get used to an increased CBD intake. Anyone wishing to use the most effective CBD Liquid for severe pain or a neurological condition must purchase appropriate liquids in higher doses after the acclimation phase.
The CBD contained in CBD Liquid addresses the body's own cannabinoid receptors. Thanks to its wide distribution throughout the body, it has effects on the psyche, the brain and the organism. However, the idea that the effect of CBD on the brain is similar to THC is illusory. However, one of the big advantages of e-liquids is the fast-acting effect. The inhalation of the E-Liquids generates an effect entry after just a few seconds. This is beneficial for chronically ill people who suffer from severe discomforts such as pain or the like. In such cases, it is particularly important to have a high CBD content and a very good quality of the liquid.
In the case of cancer, it must be questioned whether a high-quality and high-dose CBD e-liquid is sufficient in its effect, or whether the doctor should talk about one of the now prescription-only available CBD preparations with THC content. The prescription of such cannabis medication for concomitant treatment is often only possible in the final stage of a cancer.
Ingredients, THC content and aroma
Some of the questions about this topic section have already been answered in the previous chapter. With regard to the ingredients, it has to be stated that CBD is currently subject to a media hype. There is also the opportunity to realize high profit margins by trading in liquids. Therefore, it is reasonably close that some foreign manufacturers of liquids could use inferior or stretched vehicles and low quality flavors. Therefore, it is advisable to choose a reputable and certified CBD dealer from Europe.
The THC content of e-liquids in Germany has clear legal requirements that must be complied with. E-liquids, like all other CBD products, should never contain more than 0.2 percent THC. With the Vapen you notice this small THC portion possibly faster than with other dosage forms. As a rule, however, it is not noticed at all, for example in the multiply purified CBD isolates. So who buys CBD and hopes that he will get high, is subject to a mistake.
CBD liquids are not to be regarded as intoxicants, but rather as medical adjunct therapy usable. The liquids are often used for the self-treatment of chronic ailments, and for the reduction of painkillers and similar side-effect drugs. In case of doubt, the use of CBD E-Liquid should be discussed with the attending physician.
Aroma
With regard to the flavors used in the CBD Liquids Test, there are currently no findings on the health benefits or possible sequelae. Potentially, however, there are inhalation risks associated with long-term use of flavored e-liquids, which hardly anyone is aware of. Whether vaping with flavored liquids can cause or aggravate intolerance or allergy to fragrances in sensitive people is unknown.
The fact is that the flavors contained in an e-liquid with CBD have to have a food suitability according to the legislator. Nevertheless, the debate on the potential health hazards of flavored CBD liquids is controversial. It is therefore worthwhile to use the arguments of both sides in order to come to a personal judgment regarding possible risks. Which interest group stands behind the pros and cons, but for a medical layman is hardly comprehensible.
As a precaution, people suffering from chronic respiratory diseases such as pulmonary fibrosis, asthma or COPD should rather test the non-flavored CBD Liquid, but choose the pure CBD Liquid with no flavors and nicotine content. The same applies to people who suffer from chronic fragrance intolerances. From our point of view, the fragrances used present a comprehensible health risk if they are present in nicotine-containing e-liquids. The inhalation of nicotine is likely to be much lower, because it just tastes good. Every consumer is well informed today about the dangers of long-term nicotine consumption.
Use, intake, dosage during smoking or vaporization?
CBD "steaming" is generally considered to be the most efficient and healthy way to enjoy CBD consumption - provided the consumer chooses nicotine-free e-liquids. The fast-acting effect of vaping does its job. The vaporizers are already considered a success story. From the point of view of the manufacturers, they even represent the "future of the green industry". In the vaporizers, many see a healthy alternative to smoking cigarettes. There are no combustion residues in the vape that can be inhaled.
Cannabidiol has brought to the fore a whole new cannabis target. Not everyone wants to use the psychoactive substance THC to relax and get rid of stress consequences. CBD offers all the benefits of hemp to these consumers - minus the disadvantages that the THC-induced intoxication can bring with continuous use. In addition, the vaping is the most efficient use for CDB. The bioavailability of the CBD is higher in the vape than usual. For most CBD products, only a relatively small proportion of the consumed CBD enters the bloodstream.
CBD products are expected to have a percent oral bioavailability of about 15 percent. On average, only about 14 milligrams of 100 milligrams of cannabidiol enter the bloodstream. The rest is stored in body fat because it is not water soluble. To calculate is also the so-called "first pass effect", which occurs with oral CBD intake. Ingestion via the mouth - for example in a drink - causes the passage of CBD through the digestive tract. The liver eliminates part of the CBD and thus reduces its availability. However, intestinal transit can be circumvented by sublingual administration. This CBD oil is placed under the tongue.
However, when vaping or vaporizing CBD liquids, oils or flowers, we have the best method available to avoid such a high loss of bioavailability. Because here, the CBD can get directly into the lungs and into the bloodstream. The "first-pass effect" is completely nullified when evaporating CBD Liquid. Thus, four times more CBD can be taken from an e-liquid. The bioavailability of CBD increases with the vaping to 50-60 percent. In other words, it takes a much smaller amount of CBD liquid to achieve the same effect that the CBD consumer would have made with four times the amount of oral CBD oil.
Another advantage is that no meal can delay the absorption and the onset of action when steaming. When CBD evaporates oil or e-liquid with high cannabidiol content, the effect is significantly faster. That can make a difference from half an hour to half an hour. The dose of CBD may be different for a 100 milliliter capacity liquid bottle of the same size. There are 100 milliliter bottles with 25 milligrams of CBD, up to a CBD share of 500 milligrams. Basically, CBD beginners should always choose the lowest dose of 10-15 milligrams of CBD. After the acclimation phase, the dose can be increased if necessary.
The vaporizer (or vape pen) is a great way to spare your scratchy throat from smoking cigarettes with hemp ingredients. The vapors of inhaled CBD oil from a vaporizer are significantly milder. In addition, the oil or liquid can be better dosed, and controlled in the effect.
Is CBD Liquid legally available in Germany?
CBD e-liquids, and all other CBD products on the market, are legal, as long as the THC content is proven to be below 0.2 percent. But that only applies to the CBD. The THC is still a drug of intoxication, and therefore illegal. It is subject to the Narcotics Act. Legal, but prescriptive and only in the final stages of a fatal disease, some already approved drugs with CBD and THC content can be used.
Watch out for travelers who want to take their CBD and vaporizers abroad. In Thailand, for example, all THC products are strictly prohibited. Even a CBD liquid could lead to an arrest here because of its minimal residual THC content. This could potentially be the case in other travel destinations. To be on the safe side, CBD should not be consumed in such travel countries. One indication is the countries in which CBD may already be legally consumed. In all other travel countries there could potentially be problems with it - especially since CBD has not been publicly known and accepted as medically usable drugs.
Often CBD is considered as a dietary supplement, so that a medical use is considered unassignable. Possibly this will complicate the sale of CBD preparations in Germany in the future, or provide conditions. Even the aromatization removes the CBD-containing liquids from being regarded as an approved drug with proven effects.
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What should consumers pay attention to when buying?
In essence, this has already been answered elsewhere. When buying should always be paid to high quality. CBD e-liquids should only be purchased from online merchants in Europe who are trustworthy. From the consumer's point of view, Scandinavian or Swiss manufacturers are currently in the lead with good to excellent qualities. In Europe, high manufacturing standards are likely. In addition, European e-liquid manufacturers are subject to many regulations and controls that are not available in Asia or Africa. Over-priced e-liquids can not meet these standards. In our CBD Liquid Test you will find the best product.
CFD crystals test
CBD Liquid Test and Leaderboard at the top of this page.
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