#adalimumab injection

[omkarmeds]

The Most Effective Exemptia 40 injection

These injectable drugs, Cresp 40 and Exemptia 40, are becoming widely known for their therapeutic efficacy in the management of different health conditions. Both offer special benefits that can definitely boost the quality of life that is available to patients. More facts about the Cresp 40 injection and the Exemptia 40 injection can be acquired through this writing. 

Cresp 40 contains Erythropoietin (EPO). This is used most of the time as prescribed for anaemia, more so in chronic diseases related to the kidneys. The medication increases the production of red blood cells that help elevate normal counts of haemoglobin within the blood. This helps prevent fatigue and increases energy.

Adalimumab is a very potent class of drugs that falls in Exemptia 40 and is used for the treatment of various autoimmune diseases like rheumatoid arthritis and Crohn's disease. It blocks a few processes of inflammation, thereby lowering the signs of diseases to a more satisfactory extent, which ultimately improves the immunogenic behaviour of the human body against these diseases.

The advantages of convenience for both Cresp 40 and Exemptia 40 injection include that they can be given subcutaneously. Self-administration is much easier in the home setting, which might help improve adherence to treatment plans and increase flexibility for the patient.

It can be used to deliver it less frequently; therefore, most patients require delivery every one or two weeks according to their needs. Also, Exemptia 40 can be used when applied intermittently after a loading dose is performed such that the therapeutic level shall remain constant and simplify schedules of treatment, too.

Better Quality of Life

With the proper management of symptoms induced by chronic diseases, Cresp 40 or Exemptia 40 injections can greatly improve a patient's quality of life. Many patients are in less pain and have enough energy and well-being to continue their daily activities.

These are injections: Cresp 40 injection and Exemptia, 40-which have a substantial therapeutic benefit for the sick. Understanding the benefits of such drugs can help patients come together with their healthcare providers in designing effective treatment plans. Always seek professional advice and treatment.

[kexingbiopharm]

Adalimumab Solution for Injection

Adalimumab(Ahrasin) is a fully human anti-tumor necrosis factor-α(TNF-α) monoclonal antibody, a biosimilar drug of HUMIRA. Excessive inflammation in a variety of immune-mediated diseases in humans is associated with TNF-α.

[dromersheriff]

Top Rheumatoid Arthritis Doctor Chennai

Rheumatoid arthritis (RA) is a chronic autoimmune condition that affects millions of people worldwide, leading to inflammation, pain, and stiffness in the joints. Top Rheumatoid Arthritis Doctor Chennai  Over time, this condition can result in joint damage and affect mobility, severely impacting a person’s quality of life. It is essential to seek expert care and advanced treatment to manage RA effectively. In Chennai, Dr. Omer Sheriff stands out as a leading specialist in rheumatoid arthritis treatment, offering cutting-edge therapies and a patient-centered approach to care.

Understanding Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disorder where the body's immune system mistakenly attacks its own tissues, particularly the synovium—the lining of the joints. This leads to joint inflammation, swelling, and stiffness, especially in the hands, wrists, knees, and feet. The disease often affects both sides of the body symmetrically, making it easy to identify.

RA is not limited to joint problems; it can also affect other parts of the body, including the skin, eyes, lungs, heart, and blood vessels. Over time, if left untreated, RA can lead to irreversible joint damage, deformities, and even a reduced lifespan. Early diagnosis and prompt treatment are critical to controlling the symptoms and preventing further complications.

Symptoms of Rheumatoid Arthritis

The symptoms of rheumatoid arthritis can vary from person to person but commonly include:

Joint pain and swelling, particularly in the hands, wrists, and knees.

Stiffness in the joints that is usually worse in the morning or after periods of inactivity.

Fatigue, fever, and unintentional weight loss.

Symmetrical joint involvement, meaning that the same joints on both sides of the body are affected.

Recognizing these symptoms early is crucial, as timely intervention can prevent joint damage and improve the overall prognosis of the disease. Seeking consultation with a skilled rheumatoid arthritis doctor is essential for proper management.

Advanced Rheumatoid Arthritis Treatments in Chennai

Chennai offers some of the best facilities and rheumatologists for the treatment of rheumatoid arthritis. The city’s advanced medical infrastructure ensures that patients have access to the latest therapies and diagnostic tools. Dr. Omer Sheriff is one of the top rheumatologists in Chennai, offering a comprehensive approach to RA treatment that includes:

1. Disease-Modifying Antirheumatic Drugs (DMARDs)

DMARDs are the cornerstone of RA treatment. These medications slow down the progression of the disease, prevent joint damage, and improve the overall prognosis of the patient. Methotrexate, sulfasalazine, and leflunomide are common DMARDs used in the treatment of RA.

2. Biologic Agents

Biologic therapies are a newer class of treatment that target specific parts of the immune system responsible for causing inflammation. They are often prescribed to patients who do not respond to traditional DMARDs. Biologics such as TNF inhibitors (e.g., etanercept, adalimumab), interleukin inhibitors, and B-cell depleting therapies can provide significant relief and help prevent further joint damage.

3. Steroids

Corticosteroids are effective in reducing inflammation and controlling flare-ups of RA. These medications can be taken orally or injected directly into the affected joints to provide quick relief. However, due to potential long-term side effects, steroids are usually prescribed for short-term use or in combination with other medications.

4. Physical Therapy

Physical therapy is a vital component of RA management. Customized exercises and stretches help maintain joint flexibility, reduce stiffness, and improve strength. Dr. Omer Sheriff emphasizes the importance of working with physical therapists to optimize joint function and prevent further damage.

5. Surgical Interventions

In advanced cases where joint damage is severe and other treatments have not been effective, surgical options may be considered. Joint replacement surgery or arthroplasty can restore function and reduce pain. Dr. Sheriff, with his extensive experience in orthopedic care, ensures that his patients receive the best possible surgical solutions when necessary.

Dr. Omer Sheriff – Top Rheumatoid Arthritis Doctor in Chennai

Dr. Omer Sheriff is a highly respected rheumatologist in Chennai with over 24 years of experience in treating autoimmune disorders, including rheumatoid arthritis. He has a reputation for offering cutting-edge treatments and personalized care plans tailored to each patient's needs. His holistic approach to RA treatment combines medication, physical therapy, and lifestyle modifications to manage symptoms effectively.

Dr. Sheriff’s Approach to RA Treatment

Dr. Sheriff believes in a comprehensive, patient-centric approach to rheumatoid arthritis care. His treatment philosophy revolves around:

Personalized Treatment Plans: Dr. Sheriff takes into account the unique needs of each patient, developing a customized plan that may include a combination of medications, lifestyle changes, and therapies.

Advanced Medical Techniques: He stays updated with the latest advancements in rheumatology, offering his patients the most effective treatments, including biologics and newer medications.

Joint Preservation: Dr. Sheriff focuses on preventing joint damage and preserving function. Through a combination of medications and physical therapy, he helps his patients manage pain and improve mobility.

Regular Monitoring: RA is a chronic disease that requires continuous monitoring. Dr. Sheriff ensures that his patients undergo regular check-ups to track disease progression and adjust treatment as needed.

Why Choose Dr. Omer Sheriff?

There are several reasons why Dr. Omer Sheriff is a trusted choice for rheumatoid arthritis treatment in Chennai:

Expertise in Advanced Therapies: Dr. Sheriff specializes in biologics, immunosuppressive therapies, and other advanced treatments for RA, ensuring that his patients receive the best care available.

High Success Rate: His treatment methods have yielded significant improvements for his patients, helping them lead active, pain-free lives.

State-of-the-Art Facilities: Dr. Sheriff’s clinic is equipped with the latest diagnostic tools and treatment options, providing a comfortable and modern healthcare environment for his patients.

Comprehensive Care: Dr. Sheriff works with a team of physical therapists, orthopedic surgeons, and other specialists to ensure that every aspect of the patient’s treatment is addressed.

Positive Patient Outcomes: Dr. Sheriff’s patients consistently report positive experiences, with improved mobility, reduced pain, and better overall health.

Rheumatoid Arthritis Treatment Cost in Chennai

While the cost of treatment for rheumatoid arthritis can vary depending on the treatment approach, the overall expenses in Chennai are relatively affordable compared to many other cities. The cost of treatment will depend on factors such as the type of medication used, the need for biological therapies, physical therapy sessions, and any surgical interventions.

Dr. Omer Sheriff’s clinic offers a range of treatment packages to suit different budgets. During your consultation, you will be provided with a clear understanding of the expected costs, helping you plan your treatment effectively.

Conclusion

Rheumatoid arthritis is a complex, chronic condition that requires specialized care to manage its symptoms and prevent further damage. Dr. Omer Sheriff, a leading rheumatologist in Chennai, offers a comprehensive approach to treating RA, combining the latest medical treatments, personalized care plans, and a commitment to improving the quality of life for his patients. For more details visit  https://dromersheriff.com/best-orthopaedic-doctors-in-chennai/

[machendrix]

Effective Ways to Treat Scalp Psoriasis and Improve Your Quality of Life

Phototherapy involves exposing the affected skin to controlled ultraviolet (UV) light. This treatment slows down cell turnover and reduces inflammation. For severe cases of scalp psoriasis, targeted phototherapy devices like UV combs can be highly effective. When topical treatments and phototherapy aren't sufficient, systemic medications may be prescribed. These include oral or injectable drugs that suppress the immune system to reduce symptoms. Common options include methotrexate, cyclosporine, and biologics like adalimumab or etanercept.

For More Information, Please Visit phototherapy for scalp psoriasis

[harshnews]

Psoriasis Treatment Market Size, Share, Demand, Future Growth, Challenges and Competitive Analysis

"Global Psoriasis Treatment Market - Industry Trends and Forecast to 2029

Global Psoriasis Treatment Market, By Drug Class (Corticosteroids, TNF Inhibitors, Interleukins, Others), Type (Plaque Psoriasis, Psoriatic Arthritis, Others), Route of Administration (Oral, Parenteral, Topical), Application (Topical Therapeutic Drugs, Systemic Therapeutic Drugs, Combinations), End User (Hospital Pharmacy, Clinics, Retail Pharmacies, Online Sales), Country (U.S., Canada, Mexico, Peru, Brazil, Argentina, Rest of South America, Germany, Italy, U.K., France, Spain, Netherlands, Belgium, Switzerland, Turkey, Russia, Hungary, Lithuania, Austria, Ireland, Norway, Poland, Rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Vietnam, Rest of Asia Pacific, South Africa, Saudi Arabia, U.A.E, Kuwait, Israel, Egypt, Rest of Middle East and Africa) Industry Trends and Forecast to 2029.

Access Full 350 Pages PDF Report @

**Segments**

- **By Drug Class**: The psoriasis treatment market can be segmented based on drug class, which includes biologics, systemic therapy, topical therapy, and others. Biologics are becoming increasingly popular due to their targeted approach in treating psoriasis at a molecular level. Systemic therapy involves oral or injectable medications that affect the entire immune system to manage psoriasis symptoms. Topical therapies include creams, ointments, and lotions applied directly to the skin to alleviate mild to moderate symptoms.

- **By Route of Administration**: Another important segmentation in the psoriasis treatment market is based on the route of administration. This includes oral, injectable, and topical routes. Oral medications are often prescribed for systemic treatment, while injectable biologics are administered via subcutaneous or intravenous routes. Topical treatments are primarily used for localized psoriasis management.

- **By Distribution Channel**: The distribution channel segment categorizes the market based on where patients can access psoriasis treatments. This includes hospital pharmacies, retail pharmacies, online pharmacies, and specialty clinics. Hospital pharmacies are common for inpatient treatments, while retail pharmacies cater to outpatient prescriptions. Online pharmacies are gaining popularity due to convenience, and specialty clinics focus on dermatological care for psoriasis patients.

**Market Players**

- **AbbVie Inc.**: AbbVie is a leading player in the psoriasis treatment market, offering biologics like Humira (adalimumab) for psoriasis management.

- **Johnson & Johnson Services, Inc.**: Johnson & Johnson is known for its systemic therapy options for psoriasis, such as Stelara (ustekinumab) and Tremfya (guselkumab).

- **Novartis AG**: Novartis is a key player with a strong portfolio of psoriasis treatments, including Cosentyx (secukinumab) and Methotrexate.

- **Amgen Inc.**: Amgen has a range of biThe psoriasis treatment market is a dynamic and evolving sector with several key players driving innovation and advancements in treatment options for patients. AbbVie Inc. is a prominent player in the market, offering biologics like Humira (adalimumab) that have demonstrated efficacy in managing psoriasis symptoms. Biologics have gained significant traction in the market due to their targeted approach at the molecular level, offering a more personalized and effective treatment option for patients. Johnson & Johnson Services, Inc. is another major player known for its systemic therapy options such as Stelara (ustekinumab) and Tremfya (guselkumab), which have shown promise in managing moderate to severe psoriasis.

Novartis AG, with its strong portfolio of psoriasis treatments including Cosentyx (secukinumab) and Methotrexate, has been instrumental in improving outcomes for patients with psoriasis. These treatments target specific pathways involved in the development of psoriasis, providing patients with more targeted and effective treatment options. Amgen Inc., with its range of biologics like Enbrel (etanercept), has also made significant contributions to the market by providing new insights and advancements in psoriasis treatment.

The market for psoriasis treatments is witnessing a shift towards more personalized and targeted therapies, driven by advancements in biologics and systemic therapies. Biologics, in particular, have revolutionized the treatment landscape for psoriasis by targeting specific molecules involved in the inflammatory response associated with the condition. These targeted therapies have shown significant efficacy in managing psoriasis symptoms and improving quality of life for patients.

The distribution channels for psoriasis treatments play a crucial role in ensuring access to these therapies for patients. Hospital pharmacies are essential for inpatient treatments, while retail pharmacies cater to outpatient prescriptions, providing convenient access to medications for patients. Online pharmacies have also emerged as a popular choice for patients seeking convenience and accessibility in obtaining their psoriasis treatments. Specialty clinics focusing on dermatological**Global Psoriasis Treatment Market**

- **Segments** - **By Drug Class**: The psoriasis treatment market encompasses a variety of drug classes, including corticosteroids, TNF inhibitors, interleukins, and others. Corticosteroids are commonly used for their anti-inflammatory properties, while TNF inhibitors and interleukins target specific pathways in the immune system to manage psoriasis symptoms. Other drug classes offer alternative mechanisms of action for psoriasis treatment. - **By Type**: The types of psoriasis targeted in the market include plaque psoriasis, psoriatic arthritis, and other less common forms of the condition. Different types of psoriasis may require specific treatment approaches tailored to the patient's symptoms and disease progression. - **By Route of Administration**: Psoriasis treatments can be administered through various routes, such as oral, parenteral, and topical. Oral medications are often used for systemic treatment, while parenteral routes involve injections for targeted therapy. Topical treatments are applied directly to the skin for localized symptom management. - **By Application**: The applications of psoriasis treatment include topical therapeutic drugs, systemic therapeutic drugs, and combination therapies. These different applications offer a range of options for patients and healthcare providers to address the varying severity of psoriasis symptoms. - **By End User**: The end users in the psoriasis treatment market span hospital pharmacies, clinics, retail pharmacies, and online sales. Each end user plays a crucial role in ensuring access to psoriasis

The Psoriasis Treatment Market competitive landscape provides details by the competitors. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, and application dominance.

Major Points Covered in TOC:

Psoriasis Treatment Market Overview: It incorporates six sections, research scope, significant makers covered, market fragments by type, Psoriasis Treatment Market portions by application, study goals, and years considered.

Psoriasis Treatment Market Landscape: Here, the opposition in the Worldwide Psoriasis Treatment Market is dissected, by value, income, deals, and piece of the pie by organization, market rate, cutthroat circumstances Landscape, and most recent patterns, consolidation, development, obtaining, and portions of the overall industry of top organizations.

Psoriasis Treatment Profiles of Manufacturers: Here, driving players of the worldwide Psoriasis Treatment Market are considered dependent on deals region, key items, net edge, income, cost, and creation.

Psoriasis Treatment Market Status and Outlook by Region: In this segment, the report examines about net edge, deals, income, creation, portion of the overall industry, CAGR, and market size by locale. Here, the worldwide Psoriasis Treatment Market is profoundly examined based on areas and nations like North America, Europe, China, India, Japan, and the MEA.

Psoriasis Treatment Application or End User: This segment of the exploration study shows how extraordinary end-client/application sections add to the worldwide Psoriasis Treatment Market.

Psoriasis Treatment Market Forecast: Production Side: In this piece of the report, the creators have zeroed in on creation and creation esteem conjecture, key makers gauge, and creation and creation esteem estimate by type.

Keyword: Research Findings and Conclusion: This is one of the last segments of the report where the discoveries of the investigators and the finish of the exploration study are given.

What to Expect from the Report, a 7-Pointer Guide

The Psoriasis Treatment Market report dives into the holistic Strategy and Innovation for this market ecosystem

The Psoriasis Treatment Market report keenly isolates and upholds notable prominent market drivers and barriers

The Psoriasis Treatment Market report sets clarity in identifying technological standardization as well as the regulatory

framework, besides significantly assessing various implementation models besides evaluation of numerous use cases

The Psoriasis Treatment Market report is also a rich repository of crucial information across the industry, highlighting details on novel investments as well as stakeholders and relevant contributors and market participants.

A through market analytical survey and forecast references through the forecast tenure, encapsulating details on historical developments, concurrent events as well as future growth probability

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[heathcareforallworld]

Ocular Inflammation Therapeutics Market Growth and Trends: Forecast to 2032

The Ocular Inflammation Therapeutics Market is expected to witness significant growth over the forecast period leading to 2032. Ocular inflammation refers to swelling, redness, and discomfort caused by various conditions affecting the eye, such as uveitis, keratitis, conjunctivitis, and scleritis. These conditions can arise from infections, autoimmune disorders, or trauma, potentially leading to vision loss if not treated promptly. The increasing prevalence of eye-related disorders, advancements in treatment options, and the growing elderly population are key factors propelling the market's expansion.

Ocular Inflammation Therapeutics Market Size was estimated at 14.16 (USD Billion) in 2023. The Ocular Inflammation Therapeutics Market Industry is expected to grow from 14.89(USD Billion) in 2024 to 22.2 (USD Billion) by 2032. The Ocular Inflammation Therapeutics Market CAGR (growth rate) is expected to be around 5.12% during the forecast period (2025 - 2032).

Market Growth Drivers

Rising Prevalence of Ocular Inflammatory Conditions The increasing incidence of eye diseases, particularly among the aging population, is a major factor driving the demand for ocular inflammation therapeutics. Conditions such as uveitis, which affects the uveal tract of the eye, are increasingly diagnosed globally. According to the American Academy of Ophthalmology, uveitis is responsible for 10% to 15% of cases of total blindness in the U.S. alone. Other conditions such as scleritis and keratitis are also contributing to the rising demand for effective treatments.

Increasing Awareness and Early Diagnosis Awareness campaigns promoting eye health and early diagnosis of ocular inflammatory diseases are contributing to market growth. With advancements in diagnostic technologies, such as Optical Coherence Tomography (OCT) and fundus imaging, clinicians are better equipped to identify inflammation in its early stages. This leads to more prompt and effective treatment, enhancing patient outcomes and driving the demand for therapeutic solutions.

Advancements in Therapeutics and Drug Development Innovations in the field of ocular drug delivery and therapy are helping boost the market. The development of biologics, immunosuppressants, and corticosteroid formulations has transformed the treatment landscape for ocular inflammation. For example, corticosteroid implants and injectable therapies offer sustained drug release, providing long-term relief from chronic conditions like uveitis. Additionally, novel biologic therapies are emerging as targeted treatments that offer fewer side effects compared to traditional options, thus increasing adoption.

Market Segmentation

The Ocular Inflammation Therapeutics Market can be segmented based on drug class, indication, distribution channel, and geography.

By Drug Class: The market is segmented into corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), immunosuppressants, and biologics. Corticosteroids currently hold the largest share due to their widespread use in treating inflammation, although biologics are expected to see the highest growth owing to their targeted action and fewer side effects.

By Indication: Key conditions treated include uveitis, keratitis, conjunctivitis, and scleritis. Uveitis accounts for a significant portion of the market due to its frequency and potential severity.

By Distribution Channel: The primary distribution channels are hospital pharmacies, retail pharmacies, and online pharmacies. With the increasing prevalence of e-commerce and telemedicine, online pharmacies are expected to witness notable growth over the forecast period.

Key Market Trends

Biologics Gaining Traction Biologic therapies are gaining ground in the ocular inflammation therapeutics market due to their precision in targeting specific pathways involved in the inflammatory response. Biologics like adalimumab have shown significant efficacy in treating severe uveitis, reducing the need for long-term corticosteroid use and minimizing associated side effects. As more biologic treatments receive regulatory approvals, their use is expected to expand, fueling market growth.

Rising Focus on Sustained Drug Delivery The development of sustained drug delivery systems for ocular therapeutics is a growing trend. Implants and injectables that deliver medications over an extended period are becoming more popular, especially for chronic conditions like posterior uveitis. These systems improve patient compliance, reduce the frequency of dosing, and provide more consistent therapeutic outcomes.

Increasing Use of Immunosuppressants Immunosuppressants, traditionally used in organ transplantation, are now being repurposed for treating ocular inflammatory conditions, particularly in patients unresponsive to corticosteroids. Drugs like cyclosporine and tacrolimus are gaining traction as they offer long-term control of inflammation without the side effects of prolonged steroid use.

Regional Analysis

North America holds the largest share of the ocular inflammation therapeutics market due to its advanced healthcare infrastructure, high prevalence of eye diseases, and growing geriatric population. The U.S. remains a major contributor to market growth, with high healthcare spending and an increasing number of clinical trials focused on novel therapies for ocular inflammation.

Europe follows closely, with countries like Germany, France, and the U.K. leading the way in adopting advanced ocular treatments. Awareness campaigns and government initiatives aimed at preventing vision impairment are driving market demand in this region.

Asia-Pacific is expected to witness the fastest growth during the forecast period, driven by improving healthcare infrastructure, increasing access to treatment, and a large, aging population. The rising incidence of diabetes, a key risk factor for ocular inflammation, further propels the demand for therapeutics in countries like India and China.

Competitive Landscape

Key players in the AbbVie ,Novartis ,Pfizer ,Roche ,Allergan ,Regeneron ,Alcon ,Takeda ,Iluvien ,Bausch & Lomb ,Biogen ,Santen ,Bayer ,Merck & Co ,Johnson & Johnson. These companies are focusing on product development, strategic collaborations, and mergers and acquisitions to strengthen their market presence. Ongoing research into new drug formulations, biologics, and drug delivery systems is expected to create new growth opportunities in the coming years.

Conclusion

The Ocular Inflammation Therapeutics Market is poised for substantial growth through 2032, driven by increasing awareness of eye health, advancements in drug development, and the rising prevalence of ocular inflammatory conditions. Innovations in biologics, sustained drug delivery systems, and early diagnosis technologies will continue to shape the market. As the demand for effective therapies grows, especially in emerging markets, key players in the industry are well-positioned to capitalize on these opportunities, driving future expansion.

[jupiterca]

Dermatology Prescription Medications: A Comprehensive Guide

Dermatology, the branch of medicine dealing with the skin, hair, and nails, encompasses a wide array of conditions and treatments. Prescription medications play a crucial role in managing various dermatological issues, ranging from acne and eczema to psoriasis and skin infections. This article delves into the diverse world of dermatology prescription medications, highlighting their uses, benefits, and potential side effects.

Understanding Dermatology Prescription Medications

Dermatology prescription medications are drugs prescribed by a dermatologist to treat skin-related conditions. These medications can be topical (applied directly to the skin) or systemic (taken orally or injected). The choice of medication depends on the specific condition, its severity, and the patient's overall health.

Common Dermatological Conditions and Their Treatments

Acne Vulgaris

Topical Retinoids: Medications such as tretinoin and adapalene are derivatives of vitamin A. They work by promoting cell turnover and preventing the clogging of hair follicles.

Antibiotics: Topical antibiotics like clindamycin and erythromycin help reduce bacteria and inflammation on the skin. Oral antibiotics, such as doxycycline and minocycline, may be prescribed for more severe cases.

Benzoyl Peroxide: Often combined with antibiotics, benzoyl peroxide has antibacterial properties and helps to prevent resistance to antibiotics.

Hormonal Treatments: For females, oral contraceptives and anti-androgens like spironolactone can be effective in managing acne related to hormonal imbalances.

Eczema (Atopic Dermatitis)

Topical Corticosteroids: Hydrocortisone, betamethasone, and clobetasol are commonly used to reduce inflammation and itching. The potency of the corticosteroid depends on the severity of the eczema.

Calcineurin Inhibitors: Tacrolimus and pimecrolimus are non-steroidal medications that modulate the immune response and reduce inflammation.

Systemic Immunosuppressants: For severe cases, drugs like cyclosporine and methotrexate may be prescribed to suppress the immune system and control symptoms.

Psoriasis

Topical Treatments: Calcipotriene, a vitamin D analog, and topical corticosteroids are frequently used to manage mild to moderate psoriasis.

Biologic Agents: These are advanced treatments targeting specific parts of the immune system. Examples include adalimumab, etanercept, and ustekinumab.

Systemic Treatments: Methotrexate, cyclosporine, and acitretin are oral medications used for more severe cases.

Rosacea

Topical Treatments: Metronidazole and azelaic acid help reduce redness and inflammation.

Oral Antibiotics: Doxycycline and minocycline are commonly used to manage moderate to severe rosacea.

Other Treatments: Ivermectin cream and brimonidine gel can help with specific symptoms like inflammatory lesions and redness, respectively.

Fungal Infections

Topical Antifungals: Clotrimazole, miconazole, and terbinafine are used to treat fungal infections of the skin.

Oral Antifungals: For more extensive infections, oral medications like fluconazole, itraconazole, and terbinafine may be necessary.

Mechanisms of Action

The effectiveness of dermatology prescription medications lies in their diverse mechanisms of action:

Anti-inflammatory Agents: Many skin conditions are inflammatory in nature. Corticosteroids and non-steroidal medications like calcineurin inhibitors reduce inflammation and alleviate symptoms.

Antibacterial and Antifungal Agents: These medications, such as antibiotics and antifungals, target and eliminate pathogenic bacteria and fungi causing infections.

Immunomodulators: Biologics and systemic immunosuppressants modify the immune response, which is particularly beneficial in autoimmune conditions like psoriasis and severe eczema.

Cell Turnover Regulators: Retinoids and similar agents increase cell turnover, preventing clogged pores and reducing lesions in acne and psoriasis.

Side Effects and Considerations

While dermatology prescription medications can be highly effective, they are not without potential side effects. Understanding these is crucial for safe and effective treatment.

Topical Medications

Skin Irritation: Many topical medications can cause redness, burning, or peeling, especially during the initial stages of treatment.

Allergic Reactions: Some patients may develop allergic reactions to topical medications, characterized by increased redness, itching, and swelling.

Systemic Medications

Antibiotics: Long-term use can lead to antibiotic resistance and disrupt the normal flora, potentially causing secondary infections.

Immunosuppressants: These can increase the risk of infections and may have systemic side effects like liver toxicity and hypertension.

Biologics: While generally well-tolerated, biologics can sometimes cause injection site reactions and increase the risk of infections due to immune suppression.

Retinoids

Teratogenicity: Oral retinoids are highly teratogenic and can cause severe birth defects. Women of childbearing age must use effective contraception.

Dryness and Sensitivity: Both topical and oral retinoids can cause significant dryness and sensitivity to sunlight.

Advances in Dermatology Medications

Recent advancements have significantly expanded the arsenal of dermatology medications. Biologics and new small-molecule drugs offer targeted therapy with fewer side effects compared to traditional treatments. Additionally, research into the skin microbiome is opening up new avenues for treating various skin conditions by modulating the skin's natural bacterial environment.

Conclusion

Dermatology prescription medications are essential tools in managing a wide range of skin conditions. They work through various mechanisms to address the underlying causes and symptoms of dermatological diseases. However, their use requires careful consideration of potential side effects and individual patient factors. With ongoing advancements in dermatology, the future holds promise for even more effective and personalized treatments, improving the quality of life for patients worldwide.

In summary, understanding the options, mechanisms, and considerations associated with dermatology prescription medications can empower patients and healthcare providers to make informed decisions and achieve the best possible outcomes in skin health.

[futurecapstocks]

Market this week 23-12-2023

Market this week 23 12 2023 The agreement to supply adalimumab biosimilar Humira in Japan is signed by Biocon Biologics and Sandoz. The important distribution deal that Biocon Biologics Ltd (BBL), a Biocon Ltd subsidiary, signed with Sandoz grants it exclusive rights to market, sell, and distribute “Adalimumab BS for subcutaneous injection [FKB]” in Japan. With immediate effect, the deal is a…

[dr-humeira-badsha]

What are the causes of Psoriatic Arthritis?

Causes

What causes psoriatic arthritis is not known exactly. Of those with psoriatic arthritis, 40 percent have a family member with psoriasis or arthritis, suggesting heredity may play a role.

Psoriatic arthritis can also result from an infection that activates the immune system. While psoriasis itself is not infectious, it might be triggered by a streptococcal throat infection.

Who Gets Psoriatic Arthritis?

Psoriatic arthritis usually appears in people between the ages of 30 to 50,  but can begin as early as childhood. Men and women are equally at risk.

Psoriatic arthritis typically affects the large joints, especially those of the lower extremities, distal joints of the fingers and toes, and can also affect the back and sacroiliac joints of the pelvis.

How Is Psoriatic Arthritis Diagnosed?

To diagnose psoriatic arthritis, rheumatologists look for swollen and painful joints, certain patterns of arthritis, and skin and nail changes typical of psoriasis. X-rays often are taken to look for joint damage. MRI or CT scans also can be used to look at the joints in more detail.

Occasionally skin biopsies (small samples of skin removed for analysis) and blood tests are done to rule out other types of arthritis that have similar signs and symptoms, including gout and rheumatoid arthritis. In patients with psoriatic arthritis, blood tests may reveal high levels of inflammation and mild anemia.

How Is Psoriatic Arthritis Treated?

Psoriatic Arthritis treatment varies depending on the level of pain. Those with very mild arthritis may require treatment only when their joints are painful and may stop therapy when they feel better.

Non-steroidal anti-inflammatory drugs such as ibuprofen (Motrin or Advil) or naproxen (Aleve) are used as initial treatment. If arthritis does not respond, disease-modifying anti-rheumatic drugs may be prescribed. These include sulfasalazine (Azulfidine), methotrexate (Rheumatrex), cyclosporine (Neoral, Sandimmune), leflunomide (Arava) and the more recently available “anti-TNF agents” such as etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira). The anti-malarial drug hydroxychloroquine (Plaquenil) may help, but it usually is avoided as it can cause a flare of psoriasis.

Azathioprine (Imuran) may help those with severe forms of psoriatic arthritis. For severely swollen joints, corticosteroid injections can be useful. Surgery can be helpful to repair or replace badly damaged joints.

[indraprastheyetech]

 Uveitis Treatment: A Comprehensive Guide to Managing Eye Inflammation

https://eyetech.in/

Uveitis is a potentially serious eye condition that involves inflammation of the uvea, the middle layer of the eye. Left untreated, uveitis can lead to vision loss or other complications. Fortunately, there are effective treatments available to manage uveitis and alleviate its symptoms. In this blog, we will explore uveitis treatment options, their benefits, and what you can expect when seeking medical care for this condition.

Understanding Uveitis

Before diving into treatment options, let's briefly understand uveitis. It can be caused by various factors, such as infections, autoimmune diseases, or trauma to the eye. Symptoms of uveitis may include eye pain, redness, blurred vision, sensitivity to light, and floaters. The severity of uveitis can vary, and its management often requires prompt medical attention.

Treatment Approaches

Corticosteroids:

Corticosteroid eye drops, such as prednisolone, are often the first line of defense in treating uveitis. These drops help reduce inflammation and alleviate symptoms. For more severe cases, your doctor may prescribe oral or injectable corticosteroids.

Immunosuppressive Drugs:

In cases where corticosteroids alone are not sufficient or for long-term management, immunosuppressive drugs like methotrexate, azathioprine, or cyclosporine may be prescribed. These drugs work by suppressing the immune system to reduce inflammation.

Biologic Agents:

Biologic agents like adalimumab and infliximab are used when uveitis is associated with autoimmune diseases like rheumatoid arthritis or ankylosing spondylitis. These medications target specific immune system components responsible for inflammation.

Antibiotics or Antiviral Medications:

If uveitis is caused by an infection, such as bacterial or viral uveitis, antibiotics or antiviral medications will be prescribed to treat the underlying infection.

Surgical Interventions:

In some cases, surgical interventions may be necessary. This includes procedures like vitrectomy, which removes inflamed vitreous humor in the eye, or implanting slow-release steroid devices.

Benefits of Uveitis Treatment

Symptom Relief:

Uveitis treatment aims to alleviate pain, redness, and discomfort, improving your overall quality of life.

Preservation of Vision:

Effective treatment helps prevent vision loss or further complications associated with untreated uveitis.

Management of Underlying Conditions:

Treating the underlying causes of uveitis, such as autoimmune diseases or infections, can lead to better overall health.

Preventing Recurrences:

Consistent treatment and follow-up care can reduce the risk of uveitis flaring up again.

What to Expect During Treatment

Consultation:

Your journey to uveitis treatment starts with a visit to an eye specialist (ophthalmologist). They will conduct a comprehensive eye examination and gather your medical history to determine the cause and severity of your uveitis.

Treatment Plan:

Based on the diagnosis, your doctor will create a personalized treatment plan tailored to your specific needs. This may involve one or a combination of the treatment options mentioned earlier.

Medication Administration:

You will receive instructions on how to use prescribed eye drops, oral medications, or injections. It's crucial to follow the prescribed regimen meticulously.

Monitoring:

Your doctor will schedule follow-up appointments to monitor your progress, adjust medications if necessary, and ensure your uveitis is under control.

Lifestyle Adjustments:

In some cases, your doctor may recommend lifestyle changes, such as managing stress, maintaining a healthy diet, and protecting your eyes from UV rays.

Conclusion

Uveitis is a challenging eye condition that requires prompt and appropriate treatment to prevent vision loss and complications. With advancements in medical science, there are various effective treatment options available. If you experience symptoms of uveitis, consult an eye specialist immediately to receive proper diagnosis and treatment. Remember, early intervention can make a significant difference in preserving your eye health and overall well-being.

[omkarmeds]

Meropenem Injection Supplier Bangalore has Consistent Stock for Such Injection!

People choose Meropenem injection because it is a powerful antibiotic that is used to treat serious bacterial infections. The injection is also used when other antibiotics are not effective or even when the infection is severe. And it works by killing bacteria and stopping their growth which helps the body fight off the infection. The leading Meropenem injection supplier Bangalore is the top choice as they are known for providing high quality injections which are important for treating serious bacterial infections. This supplier has built a strong reputation for reliability, quality and for their excellent customer service and making them the go to option for many hospitals, clinics and even healthcare providers in Bangalore.

Doctors mainly prescribe this injection for infections in different parts of the body like the lungs, abdomen, urinary tract and also the skin. It is also used to treat infections in the brain such as meningitis. This injection is especially important for patients who are in the hospital with serious infections that need strong and fast acting treatment. With this Meropenem injection supplier Bangalore you can get the best quality Meropenem. They work with trusted manufacturers who follow strict quality control measures to ensure that each injection is safe and effective too. This means that when you choose this supplier you can trust that you are getting a product that meets the highest standards. The importance of quality cannot be overstated especially when it comes to medications like Meropenem which is used to treat severe and life threatening infections.

Another reason this supplier is highly choose is their reliability. When healthcare providers need Meropenem injections they also need them quickly. This Meropenem injection supplier Bangalore understands the urgency and ensures that they have a consistent stock of injections available. They offer prompt delivery services throughout Bangalore so clinics and hospitals can always believe on them to get the medications they need on time. This level of reliability is important in the healthcare industry and where suitable access to medications can make a major difference in patient outcomes.

People choose a commode chair for several practical and health related reasons. This chair is a moveable toilet that can be used in different locations such as beside the bed or in any room where it is needed. And it is especially useful for people who have difficulty reaching the bathroom due to mobility issues, illness or even recovery from surgery. One of the main reasons people choose a commode chair is for convenience. They are the top commode chair dealers in Bangalore and selling the top quality chair for you.

Commode chair dealers in Bangalore

Safety is another important reason why people go for a commode chair. For elderly individuals or those with limited mobility getting to the bathroom can be a dangerous task. The risk of slipping or falling increases when they have to walk a distance and especially if they are unsteady on their feet. Purchasing from the commode chair dealers in Bangalore can minimize this risk by providing a stable and easy to reach option. These chairs are designed to be comfortable and they are user friendly too. They mainly have padded seats and backrests which make them more comfortable than a regular toilet for people who need to sit for longer periods. Some models also have adjustable heights that allow users to customize the chair to their needs.

Author’s Bio:

Omkar Meds is the top Meropenem injection supplier Bangalore. As one of the leading commode chair suppliers in Bangalore, he strives hard to bring convenient to use commode chairs in cheap.

[laxmiwaprani]

Advancements in Rheumatoid Arthritis Treatment

Advancements in Rheumatoid Arthritis Treatment

A Ray of Hope for Patients Introduction

Rheumatoid Arthritis (RA) is a chronic autoimmune disease that affects millions of people worldwide. Characterized by painful joint inflammation, it can lead to severe disability if left untreated. However, there is hope on the horizon as significant advancements in RA treatment have emerged in recent years, offering patients a better quality of life and improved outcomes.

Biologics: Precision in Targeting Inflammation

One of the most remarkable breakthroughs in RA treatment has been the development of biologic medications. Biologics are designed to target specific components of the immune system that contribute to inflammation in RA. Tumor necrosis factor (TNF) inhibitors, such as Etanercept and Adalimumab, have been successful in reducing inflammation and slowing joint damage. Moreover, newer biologics like Rituximab, Tocilizumab, and Abatacept target different pathways in the immune system, providing more options and personalized treatment plans for patients.

Janus Kinase (JAK) Inhibitors: A New Class of Medications

JAK inhibitors are a relatively recent addition to the RA treatment arsenal. Medications like Baricitinib and Tofacitinib target specific enzymes involved in the inflammatory process. They have shown promise in reducing pain and inflammation in patients who do not respond well to traditional disease-modifying antirheumatic drugs (DMARDs). JAK inhibitors offer an oral alternative to injections and infusions, providing convenience for many patients.

Personalized Medicine: Tailoring Treatment to the Individual

Advancements in genetic and molecular profiling have paved the way for personalized medicine in RA treatment. Understanding a patient's genetic makeup and disease activity enables rheumatologists to choose the most effective treatment, reducing the trial-and-error approach. This not only enhances treatment efficacy but also minimizes potential side effects, promoting a better quality of life for patients.

Early Intervention and Treat-to-Target Strategies

The concept of "treat to target" has gained prominence in RA management. The goal is to achieve remission or low disease activity through aggressive treatment. Early intervention is key, as studies have shown that starting treatment within the first few months of symptom onset can significantly improve outcomes. This approach focuses on preventing joint damage and disability rather than simply managing symptoms.

Biosimilars: Expanding Access to Biologics

The introduction of biosimilars has played a pivotal role in increasing access to biologic treatments for RA. Biosimilars are highly similar versions of approved biologics, offering cost-effective alternatives. They have the potential to reduce the financial burden of RA treatment, making these life-changing medications more accessible to a broader range of patients.

Combination Therapies and Multidisciplinary Care

Rheumatologists are increasingly exploring combination therapies, which involve using two or more medications with different mechanisms of action. This approach can enhance treatment efficacy while minimizing side effects. Moreover, multidisciplinary care, including physical therapy, occupational therapy, and psychological support, plays a crucial role in improving the overall well-being of RA patients.

Conclusion

Advancements in rheumatoid arthritis treatment have transformed the landscape of care for patients living with this debilitating disease. Biologics, JAK inhibitors, personalized medicine, early intervention, biosimilars, and holistic treatment approaches have revolutionized RA management, offering patients hope for a brighter and less painful future. As research continues to push the boundaries of RA treatment, there is optimism that even more groundbreaking therapies are on the horizon, further enhancing the lives of those affected by this condition.

About Best Rheumatologist in Pune

Dr. Laxmi Waprani after completing her post-graduation worked for 2years in cardiology & Critical Care before finally moving to Rheumatology. Dr. Laxmi had a deep interest in rheumatology which went on to become her passion. Dr. Laxmi had the privilege of training for almost 3 years under internationally acclaimed rheumatologist Dr. Milind Aurangabadkar. Dr. Laxmi believes in keeping her professional knowledge & skills up to date. She keeps on doing various courses in Rheumatology. She had done post-graduate certification course in Rheumatic Diseases. Dr. Laxmi believes in educating the patient regarding his or her disease & involves patients in making decisions about their treatment.

[market-insider]

Dupuytren's Disease Market Dynamics: A Comprehensive Report

The global dupuytren’s disease market size is expected to reach USD 5.87 billion by 2030. Dupuytren’s disease is a debilitating condition characterized by the abnormal thickening and shortening of palm tissue, leading to the formation of claw-like finger deformities. This projected market expansion highlights the growing recognition of the importance of effectively addressing and treating this condition. The industry presents lucrative prospects for stakeholders, such as pharmaceutical companies, medical device manufacturers, and healthcare providers to develop innovative therapies and interventions. As the prevalence of the condition continues to rise, there is an escalating demand for effective treatments that can improve symptoms and enhance patients' quality of life.

Dupuytren’s Disease Market Report Highlights

The type II disease segment dominated the market in 2022 due to its higher prevalence, more severe symptoms, and greater demand for treatment options

In addition, advancements in medical technology have focused on addressing challenges specific to type II Dupuytren's disease, leading to a wider range of effective treatments available for patients

By type, the treatment segment held a dominant revenue share in 2022 due to the increasing demand for effective treatment options to alleviate symptoms and improve the quality of life for individuals

The hospitals end-use segment held the largest market share in 2022 due to advanced infrastructure, specialized care, and referral networks

Europe established a strong regional position in the market in 2022. This can be attributed to factors, such as advanced healthcare infrastructure, increasing prevalence of the disease, and presence of key players driving innovation and access to treatment options in the region

Gain deeper insights on the market and receive your free copy with TOC now @: Dupuytren's Disease Market Report

Consequently, intensified research and development efforts are anticipated in the near future, leading to advancements in treatment options and potential breakthroughs in managing Dupuytren's disease. In a recent study, adalimumab emerged as a potentially cost-effective treatment choice during the early stages of Dupuytren’s disease. The research findings suggest that this medication holds promise in effectively managing the condition while providing value for the investment. These results underscore the potential advantages of adalimumab as a practical and economically viable treatment option specifically for individuals in the early stages of Dupuytren’s disease. The growing awareness and understanding of the disease among healthcare professionals and patients, along with advancements in medical research and diagnostics, are driving the market expansion.

Improved detection rates and timely intervention have increased the demand for effective treatments. Endo Pharmaceuticals’ “Watching Education Unfold” campaign, featuring real patients, aims to raise awareness about Dupuytren’s contracture and educate the public and healthcare community about the condition and available treatment options. This initiative is expected to contribute to heightened awareness, early diagnosis, and improved management of contractures. In addition, significant advancements in medical technology and therapeutic approaches, such as injectable collagenase and minimally invasive surgical techniques, have played a crucial role in driving the market forward. Injectable collagenase treatment like Xiaflex has gained approval for Dupuytren's contracture in multiple countries, offering a less invasive alternative to traditional surgical procedures and leading to improved patient outcomes and shorter recovery times. These advancements in medical technology and therapeutics are significant contributors to the overall growth of the market.

[mari-musing]

Friday's Fruits 11 August 2017 💉🌸 On today's shopping list: adalimumab and Pukka tea. 🍫🍺 Spontaneous indulgences: fair trade chocolate and a stubby of gluten-free beer just because. 🍭👙 Obtuse gratitude: a nice grab of belly roll makes subcutaneous self-injection so much easier. I think it would have stung my drum-tight tum of yore so much more. ❄☔ Tangential thought: I know I am not alone in finding it difficult to motivate myself to exercise when the weather is so cold, wet and miserable. I just want to be curled up, not moving, like the dog. Moving stirs up cold air. I am becoming very good at ignoring my Garmin's commands. I am not a good role model.

[healthline-gate]

Humira Injection Pen: Medicine Uses and Side Effects - Healthline Gate

What is Humira Used For?

Humira is a medication has been used to successfully treat many arthritis, inflammatory and other diseases, however, this medication also has its share of side effects – some of which are more dangerous than others.

Learn more about this drug, from how it works to side effects, in this article.

Humira Injection Pen

The Humira injection pen works by binding to the cells in your body and preventing them from causing inflammation. Once it has bound to the cells, it blocks a protein called tumor necrosis factor (TNF). The TNF proteins tell your immune system that something is wrong in the body and that it needs to be attacked. The injection prevents blocking this message from leaving the cell, which reduces inflammation when it’s injected into the body.

How to Inject Humira Painlessly?

Follow your doctor’s instructions on how to inject the mediation. If you’re given a pen like needle, it can be injected into the fatty area of the body (stomach, thighs, hips) or the upper arms. The injection should be done in 1-inch increments, slow and steady. The needle should never be used again after it’s been injected into the body.

Is Humira an Immunosuppressant?

Unlike other biologic drugs like Remicade, Humira is not an immunosuppressant (it doesn’t reduce immune function). The mechanism of action for the medication is to block the signals that the immune system needs in order to cause inflammation. This decreases the number of inflammatory cells and cytokines that are involved in the inflammatory process.

Humira Uses

The Humira injection can be given to you in a doctor’s office, hospital, or even at your home. The injection is given into your stomach, through your thigh or buttocks with a needle and syringe. It takes about 10 minutes to give the shot. The injection site will be cleaned before giving the shot, and you might feel some discomfort when getting an injection.

The drug injection pen has been approved for use in treating the following diseases:

1. Rheumatoid Arthritis

The FDA approved Humira in 2009 for the treatment of moderate to severe rheumatoid arthritis. The side effects that occur are common and include injection site reactions, headache, stomach pain, nausea, urinary tract infection, viral infection.

The following are the ways that the injection is used to treat rheumatoid arthritis. It can be used by itself, but is often given along with one or more other treatments for this type of arthritis. The medication works by slowing down the immune system’s attack on the joints. This reduces pain and swelling in many people who take it.

2. Psoriatic Arthritis

One of the most common uses of Humira is for the treatment of psoriatic arthritis. This condition causes inflammation in your joints, which can lead to pain and stiffness. The drug works by reducing the effects of the immune system on these symptoms without causing major side effects.

The U.S. Food and Drug Administration (FDA) approved the drug to treat moderate to severe psoriatic arthritis in adults who have an inadequate response to other therapies. Patients with psoriatic arthritis can also be treated with methotrexate or a TNF inhibitor, such as Enbrel or Remicade.

3. Inflammatory Diseases

Humira is a medication that treats adalimumab-resistant inflammatory diseases. It is also known as an anti-TNF medication. It prevents the body from producing TNF alpha, which causes inflammation. The most common inflammatory diseases are Crohn’s disease or ulcerative colitis. However, some people may struggle with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis.

4. Crohn’s Disease

Humira is a drug that can be used to treat Crohn’s disease. If you’re suffering from the condition, it may affect your body in different ways depending on the type of Crohn’s you have. For example, if you have ileocolitis or colitis with ulcerative proctitis, Humira might not work for you at all. If on the other hand, you suffer from Crohn’s with fistulas and perianal disease, the drug could still help.

5. Ulcerative Colitis

Ulcerative colitis is a condition that has caused inflammation of the colon. The condition can be debilitating, and it can cause severe bleeding, weight loss, and infections. Doctors may prescribe Humira injections to reduce the symptoms. There are two ways that drug can work: it can either reduce inflammation or suppress your immune system.

6. Psoriasis

One of the many uses for Humira is to treat psoriasis. This medication is an immunosuppressant, which means it lowers your immune system’s response to foreign substances. Psoriasis is caused by an over-reaction of the immune system, so this treatment works well for that condition. One possible side effect of the medication is that your body will produce fewer natural killer cells, which helps fight infections.

7. Ankylosing Spondylitis

Ankylosing spondylitis is a type of arthritis that causes inflammation and stiffness of the spine and joints in the body. It typically starts from the neck down to the lower back. Humira is a drug that is used to treat Ankylosing spondylitis by decreasing disease activity by reducing inflammation, pain, and improving function of areas affected by AS. The medication is also may be prescribed as a preventative measure after surgery to protect against autoimmune disorders.

Humira Dose

The recommended dose for Humira is 40 mg, injected under the skin once a week. There are also doses of 20 mg and 80 mg, which can be injected as often as every other week for those who suffer from severe arthritis.

Humira Side Effects

The drug side effects are divided into two types, Physical and Psychological.

Physical side effects are common, but usually mild. These include:

Continue learning about Humira Injection Pen Uses, Dose and Side Effects...

[thepoliticalpatient]

How to get your Humira level tested thru Prometheus

I started taking Humira for my Crohn's in July of last year. Getting onto this medication was a gigantic pain in my ass, but I actually think the part that ended up being the hardest was dealing with getting my levels tested, so I wanted to write a post detailing that process. There is lots of info here that I wish I had known at the start. I actually have been wanting to write this post since last September, which was when I actually had the test done, but the whole situation didn't get fully wrapped up until today, 6 months later, and I didn't want to write it until I had complete information.

I will try very hard to make this an informative post and not just a rant but I'm not sure I have the self-restraint tbh.

OK, to start: what even is this test? With biologics, you need to maintain a high enough concentration of the drug in your system, to prevent your body from producing antibodies against the medication, and for it to be effective. My (now former - more on that soon lol) gastroenterologist is pretty passionate about making sure his patients keep a good level and will have them go on a weekly dose instead of the normal every-other-week dose if their levels aren't to his liking.

Importantly, the timing of this test is vital. You can't get it measured in the days immediately after you inject or your levels will be super high. The goal is to find out what the level is when it's at its lowest, i.e. in the day or two before your injection. My (former) gastroenterologist wanted me to get this test done between my second and third doses. That didn't end up happening because of how much of a clusterfuck this whole thing was.

So this test is only done by one company in the United States, Prometheus Biosciences. The name of the test is Anser ADA. They also have similar tests for measuring the levels of other biologics, like Anser IFX which measures Remicade levels (ADA = adalimumab, which is the generic name for Humira; IFX = infliximab, or Remicade). They have tests for Stelara and Entyvio too. If I had to guess, I'd say that the info in this post is probably pertinent to those tests as well, but I cannot guarantee it. I only know for sure about my own experience with Anser ADA.

Because this test can only be performed by Prometheus, it is likely that you cannot just go to your hospital's lab and have them draw your blood. It's possible they will do this draw for you and mail the blood to Prometheus, but you'll want to be certain to clarify this with your doctor.

My doctor's office gave me a lot of extremely wrong information, so I had no idea about this. I actually showed up at my hospital's phlebotomy lab on the morning before my third Humira dose, handed them a form that my doctor's staff had given me that contained the order for the bloodwork, and they took my blood and I thought I was done with it. Then WEEKS later at my next appointment with my doctor, he was like "did you ever get that Prometheus test done?" and I was like "wait do you not have the results back from the blood I gave weeks ago?" and he was like "you absolute imbecile, we can't do that lab for you, you need to schedule that with Prometheus's phlebotomists" (I'm paraphrasing a little bit here). To this day I have no idea what happened to the blood I gave at the lab! I assume they were like "wait what do we do with this lol" and then threw it in the garbage and didn't bother to inform me????

This was just one of many bad experiences I’ve had with this doctor/hospital, but this was the one that finally pushed me over the edge. I have since changed to a new GI at a different hospital (which was its own fucking saga, omg, it should not be so hard to get your medical records transferred from one hospital to another).

ANYWAY, my point is, be very certain to talk with your doctor about whether your hospital can draw this blood for you. If they can't, you have to call Prometheus to set up a draw with them.

Prometheus is located in California but contracts with a network of phlebotomists throughout the country. You can set up an appointment for a phlebotomist to come to your home to draw your blood.

For some goddamn reason, instead of equipping their phlebotomists with the supplies they'll need, Prometheus will mail you a package ahead of your appointment that contains some supplies.

Here's my next pro-tip: Prometheus will use some very scary language to make it sound like you need to be waiting right at the door when this package arrives and to immediately put some of the contents of the package into the freezer or else something terrible will happen. This is not true. What's actually happening here is that the package will contain some shipping supplies, including an insulated container and an ice pack, which the phlebotomist will need in order to store your blood safely. They want you to pre-freeze that ice pack before the phlebotomist arrives so that it will be ready to go as soon as your blood is drawn. That's it. So there's nothing in the package that's gonna, like, go bad or something if you don't get it into the freezer right away.

The whole thing was kind of stressful because I didn't have any tracking info on the package or anything, but it did arrive ahead of my appointment.

Okay so the next big topic here is PAYMENT. This is a $2,500 test, and most insurance doesn't cover it.

Around the same time I scheduled the draw with Prometheus, I sent a message to my insurance carrier to ask whether they would cover the test. The rep who replied to my message needed to know the CPT code for the test and the NPI for Prometheus, which I found on Prometheus's prior authorization form here. The insurance rep then said that this test would require my doctor to complete a prior authorization. If I got the prior auth, then insurance would cover the test at the out-of-network rate, which would require me to pay 35% of the cost. Without the prior authorization, they would deny the claim entirely.

I sent a message to my doctor's office asking them to complete the prior authorization stat, as I had already scheduled the draw with Prometheus and there wasn't much time. I was hesitant to cancel my draw, because that would require me to wait at least another 2 weeks (since you have to time the draw with your Humira doses), and I was already months later on this test than my doctor had originally wanted because of the whole snafu with thinking I could get it drawn at my hospital. My doctor's assistant replied and said she didn't think they'd have time to complete the prior auth, but not to cancel my appointment. She assured me that Prometheus would not charge me more than $75 if my insurance denied the claim.

I was extremely nervous about this. I was mainly concerned because I had found this info about Prometheus's payment assist program, which says that they'll reduce the charge to $75 if your income is below a certain threshold, and mine is not. Based on the info on that page, it looked like I didn’t qualify for any cost reduction, so I was pretty convinced they were gonna charge me the full $2,500.

Looking at the claims on my insurer's website, I see that Prometheus indeed tried to charge my insurance $2,500 for the test, and my insurance denied it. There is an additional $50 claim to my insurance, which insurance did pay, which I think was for the cost of having the phlebotomist visit my home.

Prometheus sent me several mailers about their payment assist program, which I just ignored because my income is too high. And for the next 6 months I sat anxiously waiting to receive a bill in the mail for several thousand dollars.

Well I'm happy to report that today, I finally received the bill from Prometheus, and it is for $75. I don't know why exactly they reduced it to that amount, but I am certainly not going to complain.

Now, I'm not certain of this, but my GUESS would be that the $75 rate is only for people who are doing self-pay. So, hilariously, if I had gotten the prior authorization done on time, my out of network coinsurance would have required me to pay 35% of the total claim, which would be $875. So, I mean....I can't guarantee that your experience will be the same as mine, but it seems to me like it is to your advantage to not go through your insurance for this test.

Oh, and Prometheus will NOT hold your test results hostage while they try to get paid. They sent the results to my doctor soon after the draw. And my levels were good!

ANYWAY, this was long, but I wanted to share everything I wish I had known before going through this. I hope it will help someone else who is trying to navigate this process!!!