#Spatial Genomics & Transcriptomics Market analysis

[versatile-blogger-1]

Global Spatial Genomics Transcriptomics Market Is Estimated To Witness High Growth Owing To Increasing Adoption of Spatial Genomics Technologies

Market Overview: Spatial genomics transcriptomics combines the technologies of spatial transcriptomics and genomics to analyze gene expression within the context of tissue architecture. This innovative approach allows researchers to study the spatial organization of gene expression within individual cells, leading to a better understanding of various biological processes and disease mechanisms. The market for spatial genomics transcriptomics is driven by the increasing adoption of these technologies in various research applications, including cancer research, neurobiology, developmental biology, and immunology. The ability to analyze gene expression within the context of tissue architecture provides valuable insights into cell-to-cell interactions, cellular heterogeneity, and spatial relationships, making it a powerful tool for biomedical research. The global Spatial Genomics Transcriptomics Market Size is estimated to be valued at US$ 262.7 million in 2023 and is expected to exhibit a CAGR of 13% over the forecast period 2023-2030, as highlighted in a new report published by Coherent Market Insights. Market Key Trends: One key trend driving the growth of the spatial genomics transcriptomics market is the increasing demand for single-cell analysis. Single-cell analysis allows researchers to study individual cells rather than bulk population samples, providing a deeper understanding of cellular heterogeneity and development. Spatial genomics transcriptomics takes single-cell analysis a step further by incorporating spatial information, enabling researchers to study gene expression within the context of tissue architecture. This integrated approach allows for a more comprehensive analysis of complex biological systems and has the potential to revolutionize our understanding of cellular processes and disease mechanisms. For example, 10x Genomics, one of the key players in the spatial genomics transcriptomics market, offers the Visium Spatial Gene Expression Solution, which enables researchers to analyze gene expression in intact tissue sections. This technology allows for the identification of cell types, mapping of gene expression, and analysis of the spatial relationships between cells. By combining single-cell analysis with spatial information, researchers can gain valuable insights into the role of gene expression in tissue development and disease progression. PEST Analysis: Political: The spatial genomics transcriptomics market is influenced by government regulations and policies regarding genomics research and healthcare. Government funding and support for research initiatives can drive market growth. Economic: The market is driven by increasing investment in genomics research and the growing demand for personalized medicine. The economic factors, such as GDP growth, healthcare expenditure, and disposable income, also impact the adoption of spatial genomics transcriptomics technologies. Social: The growing prevalence of chronic diseases and the need for better diagnostic and treatment options are driving the demand for spatial genomics transcriptomics technologies. The increasing awareness and acceptance of personalized medicine among patients and healthcare professionals are also contributing to market growth. In conclusion, the spatial genomics transcriptomics market is poised for significant growth due to the increasing adoption of these technologies in various research applications. The integration of spatial information with gene expression data provides valuable insights into cellular processes and disease mechanisms, driving the demand for spatial genomics transcriptomics technologies. With advancements in genomics research and technological innovation, this market is set to revolutionize our understanding of biology and contribute to the development of personalized medicine.

[pranalip]

Spatial Genomics & Transcriptomics Market Future Market Projections and Strategies 2024-2033 | Global Insight Services

Global Insight Services has recently updated its global market reports, now including the latest data for 2024 and projections through 2033.

Spatial Genomics & Transcriptomics are two branches of the field of genomics and transcriptomics that focus on the study of the spatial organization of genes and transcripts. This field combines genetics, genomics, and transcriptomics to investigate the spatial organization of genetic material and the regulation of gene expression in different cellular environments.

Spatial genomics focuses on the study of the physical arrangement of genes in the genome and their regulation. This involves the study of the 3D structure of the genome, which includes the location, orientation, and interaction of genes with each other. It also involves investigating the regulation of gene expression, including transcriptional and post-transcriptional regulation.

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Transcriptomics, on the other hand, focuses on the study of the expression of genes and their regulation. This involves analyzing the levels of gene expression, including mRNA and protein levels, in different cellular environments. It also involves investigating the regulation of gene expression, including transcriptional and post-transcriptional regulation.

The combination of spatial genomics and transcriptomics provides a comprehensive view of the regulation of gene expression and the physical organization of the genome. This information is important for understanding the role of genes and transcripts in health and disease, and can be used to develop new treatments and therapies.

Key Trends

The key trends in spatial genomics and transcriptomics technology include:

High-Throughput Sequencing: High-throughput sequencing (HTS) is a form of next-generation sequencing (NGS) that can quickly and accurately sequence many different genomes. By combining this technology with spatial genomics and transcriptomics, researchers can map the precise locations of genes and their expression levels within the body.

Single-Cell Analysis: This technology enables researchers to study individual cells at the single-cell level, providing a more detailed understanding of the genetic makeup of an individual or population. By studying individual cells, researchers can gain insights into how different genes interact, as well as how mutations affect gene expression.

Automated Image Processing: Automated image processing tools can be used to quickly analyze large volumes of data generated from spatial genomics and transcriptomics experiments. These tools allow researchers to quickly identify patterns in the data, which can provide valuable insights into the genetic makeup of an individual or population.

Machine Learning: Machine learning algorithms are increasingly being used to analyze spatial genomics and transcriptomics data. These algorithms can be used to identify patterns in the data that may not be obvious to the human eye, providing insights into the genetic makeup of an individual or population.

Advanced Visualization: Advanced visualization tools are being used to generate interactive visualizations of spatial genomics and transcriptomics data. These tools allow researchers to quickly identify patterns in the data and to gain a better understanding of the genetic makeup of an individual or population.

Key Drivers

The key drivers of the Spatial Genomics & Transcriptomics market are the increasing demand for precision medicine, the development of new technologies, and the availability of data. The demand for precision medicine is driven by the need to improve patient outcomes and reduce healthcare costs. As the cost of sequencing technologies decreases, they are becoming more widely available, allowing researchers to generate larger data sets and identify new gene expression patterns. New technologies, such as single-cell sequencing, are also enabling researchers to gain a better understanding of the complexity of gene expression patterns. In addition, the availability of data from public and private sources is allowing researchers to conduct larger-scale studies.

The development of new analytical tools is also driving the Spatial Genomics & Transcriptomics market. Tools such as artificial intelligence (AI) and machine learning are being used to analyze large datasets in order to identify novel patterns and correlations. AI-based tools can also be used to generate predictive models that can be used to identify potential drug targets or predict patient response to treatment.

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The increasing demand for personalized medicine is also driving the Spatial Genomics & Transcriptomics market. Personalized medicine involves the use of gene expression data to tailor treatments to individual patients. By understanding the molecular basis of disease, personalized treatments can be developed that are tailored to the individual patient’s genetic makeup.

Finally, the increasing demand for data-driven decision making in the healthcare industry is driving the Spatial Genomics & Transcriptomics market. By leveraging gene expression data, healthcare providers can make more informed decisions about patient care and treatment. This data can be used to identify potential drug targets, identify biomarkers of disease, and evaluate drug efficacy.

Research Objectives

Estimates and forecast the overall market size for the total market, across product, service type, type, end-user, and region

Detailed information and key takeaways on qualitative and quantitative trends, dynamics, business framework, competitive landscape, and company profiling

Identify factors influencing market growth and challenges, opportunities, drivers and restraints

Identify factors that could limit company participation in identified international markets to help properly calibrate market share expectations and growth rates

Trace and evaluate key development strategies like acquisitions, product launches, mergers, collaborations, business expansions, agreements, partnerships, and R&D activities

Thoroughly analyze smaller market segments strategically, focusing on their potential, individual patterns of growth, and impact on the overall market

To thoroughly outline the competitive landscape within the market, including an assessment of business and corporate strategies, aimed at monitoring and dissecting competitive advancements.

Identify the primary market participants, based on their business objectives, regional footprint, product offerings, and strategic initiatives

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Market Segmentation:

The Spatial Genomics & Transcriptomics Market is segmented into product type, application, end-user, and region. Based on product type the market is categorized into Instruments, Consumables and Software. On the basis of application, it is further segmented into Translational Research and Drug Discovery & Development. Based on end-user it is segmented into Pharmaceutical & Biotechnology Companies, Contract Research Organizations and Academic & Research Institutes. Whereas based on region, it is divided into North America, Europe, Asia-Pacific, and Rest of the World .

Key Players:

The Spatial Genomics & Transcriptomics Market Report includes players such as 10x Genomics, Inc. (U.S), NanoString Technologies, Inc. (U.S), Seven Bridges Genomics Inc. (U.S), Akoya Biosciences, Inc. (U.S), ZEISS Group (Germany), Dovetail Genomics, LLC (U.S), Phase Genomics, Inc. (U.S), Spatial Transcriptomics AB (Sweden), RevoluGen Ltd. (U.K) and S2 Genomics, Inc. (U.S), among others.

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Research Scope

Scope – Highlights, Trends, Insights. Attractiveness, Forecast

Market Sizing – Product Type, End User, Offering Type, Technology, Region, Country, Others

Market Dynamics – Market Segmentation, Demand and Supply, Bargaining Power of Buyers and Sellers, Drivers, Restraints, Opportunities, Threat Analysis, Impact Analysis, Porters 5 Forces, Ansoff Analysis, Supply Chain

Business Framework – Case Studies, Regulatory Landscape, Pricing, Policies and Regulations, New Product Launches. M&As, Recent Developments

Competitive Landscape – Market Share Analysis, Market Leaders, Emerging Players, Vendor Benchmarking, Developmental Strategy Benchmarking, PESTLE Analysis, Value Chain Analysis

Company Profiles – Overview, Business Segments, Business Performance, Product Offering, Key Developmental Strategies, SWOT Analysis.

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[ilmemcmi]

Spatial Omics Market Increasing Adoption of Spatial Omics in Drug Discovery and Diagnostics

Spatial omics refers to technologies that help localize gene expression and other molecular information in cells and tissues at subcellular resolution to analyze biological systems. Spatial omics allows simultaneous mapping of multiple targets in intact biological tissues to understand complex biological processes and disease pathogenesis. The technology helps obtain genomic, transcriptomic and proteomic details from specific cell types or structures within tissues. This provides better insights compared to conventional bulk-omics techniques that generate averaged measurements from biological samples containing mixed cell populations. With its ability to generate molecular spatial information while preserving tissue architecture, spatial omics is finding rising application in drug discovery, diagnostics and clinical research. Global spatial omics market is estimated to be valued at USD 315.5 Mn in 2024 and is expected to exhibit a CAGR of 9.4% during the forecast period (2024-2031).

Growing use of spatial omics techniques like spatial transcriptomics, mass spectrometry imaging and others in academic and pharmaceutical research is a key factor driving market growth. Spatial Omics Market Growth is being widely adopted by pharmaceutical companies for target identification and validation, biomarker discovery, toxicity prediction and drug efficacy evaluation during preclinical development. It is also finding increasing use in clinical applications like cancer diagnostics, immuno-oncology and neuroscience research. Spatial information helps gain a better understanding of tissue heterogeneity, cellular interactions and biomarker correlations, fueling demand for spatial omics technologies. Key Takeaways Key players operating in the spatial omics market are Gilson Company, Inc., Russell Finex Ltd., Retsch GmbH, Lao Soung Machinery Co. Ltd., Endecotts Ltd., Bionics Scientific Technologies Ltd., and Thermo Fischer Scientific, Advantech Manufacturing, Dual Manufacturing Co., Inc., and GKM Siebtechnik GmbH. Key opportunities in the spatial omics market include development of spatial omics assays and kits specific to various disease areas. This will help facilitate broader adoption of the technology across diagnostic and clinical settings. Growing investments by pharmaceutical and biotech companies in spatial biology startups is another opportunity area. Globally, North America currently dominates the spatial omics market owing to significant research funding and presence of major market players. However, Asia Pacific is anticipated to emerge as the fastest growing regional market over the forecast period driven by increasing R&D spending, biotech investments and focus on precision medicine in countries like China, India and Japan. Key players are also expanding their geographical presence across emerging markets through partnerships and new facilities. Market Drivers and Restrain The key driver for the spatial omics market is increasing focus on precision medicine. Spatial omics techniques help gain molecular insights from individual cells and regions within tissues to better understand disease pathogenesis, predict treatment response and develop targeted therapies. This supports the underlying goal of precision medicine to provide personalized healthcare based on individual patient profiles. Another major driver is rising funding for spatial biology research from government and private organizations worldwide as spatial omics holds potential to accelerate drug discovery processes. The high costs of instruments and software tools required for spatial omics experiments act as a key restraint. Spatial profiling techniques currently generate large datasets requiring costly infrastructure for data analysis, storage and sharing. Limited availability of trained professionals with expertise in spatial analysis also poses a challenge. Standardization issues associated with sample preparation, data acquisition and software tools can hamper wider adoption of spatial omics methods. However, technology advancements are expected to progressively address these restraints over the coming years.

Segment Analysis

Spatial omics sub-segment dominates the market currently. Spatial omics techniques help analyze the expression of genes and proteins at a spatial level within a tissue sample. These techniques can capture molecular information from a whole tissue slice or a tissue section in its native spatial context, enabling the visualization and mapping of molecular landscapes with cellular resolution. Advances in spatial omics techniques like multiplexed ion beam imaging (MIBI), multiplexed error-robust fluorescence in situ hybridization (MERFISH), and spatial transcriptomics are driving the growth of this sub-segment. Global Analysis

North America is expected to be the fastest growing as well as the dominating regional market during the forecast period. The presence of leading spatial omics players and availability of research funding for spatial analysis from government as well as private organizations are driving the growth of the market in this region. Asia Pacific is also expected to witness high growth rate owing to increasing research activities in countries like China and India. Research institutions and pharmaceutical companies in Asia Pacific are widely adopting spatial omics techniques for applications like biomarker discovery and drug development.

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About Author:

Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163)

[businessresearchreportss]

An Overview of the Next Generation Sequencers Market: Trends and Insights

The next-generation sequencers (NGS) market is characterized by rapid technological advancements, expanding applications across various fields, and growing adoption of genomic technologies for research, diagnostics, and precision medicine.

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Here's an overview of the trends and insights shaping the NGS market:

1. Market Growth and Size:

The NGS market continues to grow rapidly, driven by increasing demand for high-throughput sequencing technologies, declining sequencing costs, and expanding applications in genomics research, clinical diagnostics, and personalized medicine.

Market research reports project robust growth rates for the NGS market, with estimates of the market size reaching billions of dollars globally.

2. Technological Advancements:

Continuous technological advancements in NGS platforms, sequencing chemistry, and bioinformatics tools enhance sequencing accuracy, throughput, and data quality.

Innovations such as single-molecule sequencing, nanopore sequencing, long-read sequencing, and spatial transcriptomics expand the capabilities of NGS technologies and enable new applications in genomic analysis.

3. Expanding Applications:

NGS technologies find applications across a wide range of fields, including genomics, oncology, reproductive health, infectious diseases, agriculture, forensics, and environmental research.

NGS is increasingly used for whole-genome sequencing, exome sequencing, transcriptome analysis, epigenomics, metagenomics, and microbiome studies, driving demand for sequencing services and bioinformatics solutions.

4. Precision Medicine and Clinical Diagnostics:

NGS plays a pivotal role in advancing precision medicine initiatives by enabling comprehensive genomic profiling, molecular diagnostics, and targeted therapies for cancer and rare diseases.

Clinical applications of NGS include cancer genomics, inherited genetic disorders, pharmacogenomics, prenatal screening, infectious disease detection, and liquid biopsy testing, contributing to personalized treatment approaches and improved patient outcomes.

5. Integration with Other Technologies:

Integration of NGS with other technologies, such as artificial intelligence (AI), machine learning, CRISPR/Cas9 gene editing, and single-cell analysis, enhances data analysis, interpretation, and biological insights.

Multi-omics approaches combining genomics, transcriptomics, proteomics, and metabolomics data provide comprehensive insights into complex biological systems and disease mechanisms.

6. Shift towards Clinical Sequencing:

There is a growing trend towards clinical adoption of NGS technologies in healthcare settings, including hospitals, diagnostic laboratories, and academic medical centers.

Regulatory approvals, reimbursement policies, and guidelines for NGS-based tests are facilitating the integration of genomic sequencing into routine clinical practice for disease diagnosis, prognosis, treatment selection, and monitoring.

7. Cost Reduction and Accessibility:

Declining sequencing costs, improvements in sequencing efficiency, and scalability of NGS platforms make genomic sequencing more accessible and affordable for research laboratories and clinical laboratories worldwide.

Increased competition among NGS instrument manufacturers, service providers, and sequencing reagent suppliers drives cost optimization and innovation in the market.

8. Data Management and Bioinformatics:

Effective data management, storage, analysis, and interpretation remain critical challenges in NGS research and clinical applications.

Bioinformatics tools, software solutions, and cloud-based platforms are developed to address the growing volume, complexity, and diversity of genomic data generated by NGS experiments, enabling researchers to extract meaningful insights from large-scale sequencing datasets.

9. Regulatory Landscape and Quality Assurance:

Regulatory agencies worldwide, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), provide guidance and oversight for NGS-based tests, ensuring analytical validity, clinical utility, and quality assurance.

Quality control standards, proficiency testing programs, and accreditation requirements for NGS laboratories promote standardized practices and ensure the reliability and reproducibility of sequencing results.

10. Global Market Dynamics:

The NGS market exhibits regional variations in adoption rates, market penetration, and regulatory frameworks across different geographic regions, influenced by factors such as healthcare infrastructure, funding availability, research priorities, and economic conditions.

Overall, the next-generation sequencers market continues to evolve rapidly, driven by technological innovation, expanding applications, and increasing demand for genomic solutions in research, clinical diagnostics, and healthcare. As NGS technologies mature and become more integrated into routine practice, they hold immense promise for advancing our understanding of the genome and improving patient care in diverse fields of medicine and biology.

[omkarpatel]

Spatial Genomics Transcriptomics is Estimated to Witness High Growth Owing to Opportunity of Healthcare Advancements

Spatial genomics transcriptomics is an emerging technique which allows simultaneous analysis of RNA expression levels within individual cells in their original tissue context at high resolution. It enables unbiased mapping of the cellular composition of tissues and detecting cell types, states and interactions in situ. The technique combines spatial imaging with sequencing to determine where transcripts are located in fixed and stained tissues. This provides immense advantages over other bulk tissue RNA-seq techniques as it offers spatial context and cellular resolution of gene expression.

The global Spatial Genomics Transcriptomics Market s estimated to be valued at US$ 450 million in 2023 and is expected to exhibit a CAGR of 13% over the forecast period 2023-2030, as highlighted in a new report published by Coherent Market Insights. Market Opportunity: The key opportunity driving the high growth of the spatial genomics transcriptomics market is its potential to advance healthcare. Spatial genomics can unravel the complex interplay between cells in healthy and diseased tissues. This technique is being applied to further understand various disease conditions like cancer at an unprecedented scale and resolution. Researchers are mapping expression of genes in tissues to gain novel insights into development and progression of diseases. Spatial understanding of genetic changes in situ can prove pivotal in discovering biomarkers and designing more precise therapies. Several biopharma companies are investing heavily in spatial genomics to accelerate drug discovery and development efforts. The ability of this technique to provide precise spatial mapping of gene expression holds immense potential to transform healthcare in the coming years. Porter’s Analysis Threat of new entrants: The spatial genomics transcriptomics market requires high capital investment and established distribution channels which poses significant barriers for new players. Bargaining power of buyers: Large pharmaceutical companies have strong bargaining power due to their high volume purchases. However, various product options provide flexibility to buyers. Bargaining power of suppliers: Key technology providers like 10x Genomics have considerable influence over prices and innovations. Nonetheless, their dependence on a small buyer base mitigates bargaining power. Threat of new substitutes: Limited substitutes exist for spatial genomics transcriptomics techniques due to their unique capability to detect molecular profiles of tissues at high resolution. Competitive rivalry: Players like NanoString and Illumina compete intensely on technology advancements, licensing deals and geographic expansions. SWOT Analysis Strength: Spatial genomics transcriptomics provides comprehensive single-cell analysis without requiring cell dissociation. It allows mapping gene expression in anatomical context of tissues. Weakness: High costs, complex workflow and heavy data analysis requirements restrict wider adoption. Challenges remain in achieving optimal resolution, scale and specificity. Opportunity: Growing R&D in genomics, drug discovery and development is stimulating demand. Potential clinical applications include cancer diagnostics, neuroscience and inflammatory diseases. Threats: Stringent regulatory norms and data privacy laws pose compliance issues. Slow commercialization compared to other omics technologies. Key Takeaways The global spatial genomics transcriptomics market is expected to witness high growth. Advancing capabilities to reveal cell-type organization and gene correlations at microanatomical scales will support market rise. The global Spatial Genomics Transcriptomics Market is estimated to be valued at US$ 300 million in 2023 and is expected to exhibit a CAGR of 13% over the forecast period 2023-2030. North America dominates current demand owing to extensive research and technology development activities in the region. Asia Pacific is likely to be the fastest growing market for spatial genomics transcriptomics during the forecast period. Countries like China, India and South Korea are strengthening genomic research infrastructure which will support technology adoption. Key players: Key players operating in the spatial genomics transcriptomics market are 10x Genomics, NanoString Technologies, Seven Bridges Genomics, Dovetail Genomics, S2 Genomics and others. 10x Genomics has established itself as the market leader by launching product upgrades frequently and filing patents for new techniques.

[john9028]

Spatial Genomics and Transcriptomics Market share,trends,application and demand analysis 2033

Spatial genomics and transcriptomics are innovative technologies that allow the visualization and analysis of gene expression patterns and their spatial distribution within tissues or even single cells. These techniques combine the power of traditional genomics and transcriptomics with high-resolution imaging to provide a comprehensive understanding of gene expression at a spatially resolved level. Spatial genomics aims to study the organization and function of the genome within the three-dimensional (3D) context of the cell or tissue. It allows researchers to map the location of genes, regulatory elements, and structural variations within the genome in situ, providing valuable information about the architecture and regulation of the genome. On the other hand, spatial transcriptomics is a technique that enables the spatial mapping of transcriptomes, which are the complete set of RNA transcripts produced by a cell or tissue. By preserving the spatial information of the transcriptome,.

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[techscitumbler]

Cancer Transcriptome Atlas launched a new product based on Nano String Technologies' and launched a new platform called as GeoMx Digital Spatial Profiler (DSP) platform, which is used for readout on Illumina's next-generation sequencing (NGS) technology.

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Spatial Genomics and Transcriptomics Market is anticipated to witness impressive growth during the forecast period. This can be ascribed to growing demand for early diagnosis and remedial treatment and developing innovative products for the treatment of chronic diseases.

#healthcare#healthcareindustry#pharmaceuticalindustry#clinicaltrials#opportunities#biotechnology#growth

[fusiontechnologyankush]

Spatial Genomics & Transcriptomics Market 2022 Global Industry Share, Growth, Drivers, Emerging Technologies, and Forecast Research Report 2028

Report Summary

The Spatial Genomics & Transcriptomics Market report provides a detailed analysis of global market size, regional and country-level market size, segmentation market growth, market share, competitive Landscape, sales analysis, impact of domestic and global market players, value chain optimization, trade regulations, recent developments, opportunities analysis, strategic market growth analysis, product launches, area marketplace expanding, and technological innovations.

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The report offers detailed coverage of Spatial Genomics & Transcriptomics industry and main market trends with impact of coronavirus. The market research includes historical and forecast market data, demand, application details, price trends, and company shares of the leading Spatial Genomics & Transcriptomics by geography. The report splits the market size, by volume and value, on the basis of application type and geography.

At the same time, we classify Spatial Genomics & Transcriptomics according to the type, application by geography. More importantly, the report includes major countries market based on the type and application. Finally, the report provides detailed profile and data information analysis of leading Spatial Genomics & Transcriptomics company.

The major players included in the report are NanoString Technologies Seven Bridges Genomic Horizon Discovery Group CARTANA Advanced Cell Diagnostics 10x Genomics Dovetail Genomics Illumina S2 Genomics

Based on the type of product, the global Spatial Genomics & Transcriptomics market segmented into Instruments Consumables Software

Based on the end-use, the global Spatial Genomics & Transcriptomics market classified into Academic Research Pharmaceutical Manufacturer Others

Based on geography, the global Spatial Genomics & Transcriptomics market segmented into North America (United States, Canada and Mexico) Europe (Germany, UK, France, Italy, Russia and Spain etc.) Asia-Pacific (China, Japan, Korea, India, Australia and Southeast Asia etc.) South America (Brazil, Argentina and Colombia etc.) Middle East & Africa (South Africa, UAE and Saudi Arabia etc.)

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Table of Contents

1 RESEARCH SCOPE 1.1 Research Product Definition 1.2 Research Segmentation 1.2.1 Product Type 1.2.2 Main product Type of Major Players 1.3 Demand Overview 1.4 Research Methodology

2 GLOBAL Spatial Genomics & Transcriptomics INDUSTRY 2.1 Summary about Spatial Genomics & Transcriptomics Industry

2.2 Spatial Genomics & Transcriptomics Market Trends 2.2.1 Spatial Genomics & Transcriptomics Production & Consumption Trends 2.2.2 Spatial Genomics & Transcriptomics Demand Structure Trends 2.3 Spatial Genomics & Transcriptomics Cost & Price

3 MARKET DYNAMICS 3.1 Manufacturing & Purchasing Behavior in 2020 3.2 Market Development under the Impact of COVID-19 3.2.1 Drivers 3.2.2 Restraints 3.2.3 Opportunity 3.2.4 Risk

4 GLOBAL MARKET SEGMENTATION 4.1 Region Segmentation (2017 to 2021f) 4.1.1 North America (U.S., Canada and Mexico) 4.1.2 Europe (Germany, UK, France, Italy, Rest of Europe) 4.1.3 Asia-Pacific (China, India, Japan, South Korea, Southeast Asia, Australia, Rest of Asia Pacific) 4.1.4 South America (Brazil,, Argentina, Rest of Latin America) 4.1.5 Middle East and Africa (GCC, North Africa, South Africa, Rest of Middle East and Africa) 4.2 Product Type Segmentation (2017 to 2021f) 4.2.1 Instruments 4.2.2 Consumables 4.2.3 Software 4.3 Consumption Segmentation (2017 to 2021f) 4.3.1 Academic Research 4.3.2 Pharmaceutical Manufacturer 4.3.3 Others

5 NORTH AMERICA MARKET SEGMENT 5.1 Region Segmentation (2017 to 2021f) 5.1.1 U.S. 5.1.2 Canada 5.1.3 Mexico 5.2 Product Type Segmentation (2017 to 2021f) 5.2.1 Instruments 5.2.2 Consumables 5.2.3 Software 5.3 Consumption Segmentation (2017 to 2021f) 5.3.1 Academic Research 5.3.2 Pharmaceutical Manufacturer 5.3.3 Others 5.4 Impact of COVID-19 in North America

What our report offers: – Market share assessments for the regional and country-level segments – Strategic recommendations for the new entrants – Covers Market data for the years 2020, 2021, 2022, 2025, and 2028 – Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations) – Strategic recommendations in key business segments based on the market estimations – Competitive landscaping mapping the key common trends – Company profiling with detailed strategies, financials, and recent developments – Supply chain trends mapping the latest technological advancements

Free Customization Offerings: All the customers of this report will be entitled to receive one of the following free customization options: • Company Profiling o Comprehensive profiling of additional market players (up to 3) o SWOT Analysis of key players (up to 3) • Regional Segmentation o Market estimations, Forecasts and CAGR of any prominent country as per the client’s interest (Note: Depends on feasibility check) • Competitive Benchmarking o Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

[desaletushki]

Omics-Based Clinical Trials Market Size Is Anticipated To Reach $49.5 Billion By 2030

The global omics-based clinical trials market size is anticipated to reach USD 49.5 billion by 2030, according to the new report of Grand View Research, Inc. The market is expected to expand at a CAGR of 7.4% from 2022 to 2030. Omics has turned out to be the most advanced approach in molecular research. It includes all the field of biological sciences that ends with the suffix - omics. Various disciplines can be classified as omics such as proteomics, genomics, transcriptomics, and metabolomics. The outbreak of coronavirus accelerated the adoption of new approaches, models, and technology in clinical trials, this has positively impacted market growth.

The outbreak of COVID-19 has caused havoc and has disrupted almost every sector of industry.

Initially, the outbreak has negatively impacted the ecosystem of clinical trials and affected many ongoing studies for numerous indications. However, in the second half of 2020, researchers started developing innovative therapeutics and vaccines against COVID-19, which has supported the market recovery and growth, and continuance of business by CROs. There has been an increase in the clinical trials activity with oncology trials attaining historically high levels. The extensive research for understanding the COVID-19 infection has turned the attention to the application of omics-based studies.

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For instance, in June 2021, a group of researchers at University Hospital Tuebingen initiated a clinical trial on comparative genetic and immune response analysis of different COVID-19 vaccine candidates using a multi-omics approach. The growing application of spatial OMICS, for the identification of biomarkers, is a major factor boosting the growth of the market. To study the efficacy and toxicity of the drug, spatial OMICS play a major role and have simplified drug discovery and development. Biomarker identification along with the clinical application is widely used in drug development and discovery. Biomarkers are used to identify the pathway of the diseases and the progression and help to understand the cause.

The rising prevalence of chronic diseases such as cancer and cardiac disorders and the increasing demand for omics-based clinical trials in developing countries are boosting the market’s growth. Cancer is one of the leading causes of death in the United States. In 2018 alone, there were an estimated 1,735,350 new diagnoses and 609,640 cancer-related deaths. Single-cell multi-OMIC analysis is a novel tool that is opening doors in cancer drug development and further advance the current treatment options. The market is also driven by a rising number of biologics, demand for advanced technologies, and the need for personalized medicines and orphan drugs. Additionally, growing biotechnology and the pharmaceutical industry have propelled the demand for non-invasive instruments, full applications for single-cell multi-omics technology, and conventional labs are bolstering future market growth.

Omics-Based Clinical Trials Market Highlights

By phase type, phase II segment held the largest market share in 2021 with a share of 37.8% due to the major number of phase II omics-based ongoing clinical trials

Based on the study design, interventional studies had the highest market share in 2021 since, among the three types of studies, interventional studies accounted for a larger number of clinical trials, especially in oncology

The oncology segment dominated the indication segment in 2021 owing to the rising research attention in the field and increasing demand for omics-based clinical trials for early detection and prevention of the disease

North America is expected to maintain its lead in the market over the forecast period owing to technological advancements, rising R&D, and the presence of major pharmaceutical and biotechnology players in the region

Key Companies & Market Share Insights

The market for omics-based clinical trials is highly competitive in nature due to the presence of a substantial number of developed as well as medium to small-sized organizations Several market participants are privately held or are a part of private equity firms’ portfolios. For instance, In March 2018, Danaher Corporation acquired Integrated DNA Technologies. This acquisition aimed at expanding Danaher’s presence in the highly attractive genomics market. Another company is Rebus Biosystems Inc., a U.S.-based life science technology company in December 2021, announced that it has acquired the assay assets and IP of EEL Transcriptomics AB, a company that is privately held focused on high-plex spatial transcriptomics based on single-cell resolution. Some of the prominent players in the omics-based clinical trials market include: Parexel International Corporation, Pharmaceutical Product Development (PPD), Charles River Laboratory, ICON plc, SGS SA, Eli Lilly and Company, Pfizer Inc., Covance Inc., Novo Nordisk, Rebus Bio

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Spatial Genomics & Transcriptomics Market Size, Share, Growth Trends, Analysis and Forecast 2019-2027

Spatial Genomics & Transcriptomics Market: Overview

The spatial genomics & transcriptomics market is prognosticated to bring profitable growth during the assessment period of 2019-2027. The growing incidence of various genetic disorders such as neurological disorders, cancer, and others will bring tremendous growth prospects for the spatial genomics & transcriptomics market. Technological advancements in the genetic engineering space will also play a vital role in the growth of the spatial genomics & transcriptomics market.

·         An increase in the collaborations between research institutes and numerous countries will have a positive impact on the growth of the spatial genomics & transcriptomics market. The players are focusing on these activities for deriving new formulations and upgrading their processes. These upgrades help in providing enhanced convenience and benefit to the consumers, eventually increasing the growth rate of the spatial genomics & transcriptomics market.

 ·         Mergers, acquisitions, partnerships, and joint ventures are crucial for the spatial genomics & transcriptomics market growth. The players indulge in these collaborations for expanding their foothold across the spatial genomics & transcriptomics market, ultimately sowing the seeds of growth. The players also concentrate on expanding their service offerings. This factor will have a profound impact on the growth of the spatial genomics & transcriptomics market.

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 Global Spatial Genomics & Transcriptomics Market: Introduction

 Spatial genomics & transcriptomics enables researchers to not only see what is in a cell but how cells are organized in relation to one another, offering invaluable insights into understanding a disease by using the data that was earlier beyond the reach of modern methods. Spatial genomics & transcriptomics incorporates the exploration and assortment of transcriptomes. It has diverse applications, primarily in molecular genetics. The global spatial genomics & transcriptomics market is witnessing a lot of instances of new product launches. For example, Trio RNA-Seq launched by NuGEN Technologies, Inc. is particularly suitable for use in low-abundance transcript applications, as it offers an extremely sensitive whole transcriptomics solution. This innovation embodies three powerful technologies for performing high-sensitivity ribonucleic acid (RNA) analysis: single-primer isothermal amplification (SPIA), DimerFree, and AnyDeplete.

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Global Spatial Genomics & Transcriptomics Market: Competition Landscape

Key players operating in the global spatial genomics & transcriptomics market are focusing on mergers and acquisitions. For instance, in December 2018, 10X Genomics acquired Spatial Transcriptomics, a pioneer in the emerging field of spatial genomics. Spatial Transcriptomics offers a technology designed to allow RNA sequencing to perform in the 2D technology. In August 2018, 10X Genomics acquired Epinomics, a pioneer in the growing space of epigenetics. The acquisition would provide 10X Genomics with the ATAC-seq technology and fundamental IP to accelerate discoveries and conduct further research in epigenomics.

10X Genomics

Founded in 2012, 10X Genomics is headquartered in California, the U.S. The company develops integrated systems and solutions for genome sequencing, exome sequencing, and single-cell transcriptomics. 10X Genomics, Inc. was formerly known as 10X Technologies, Inc. and it changed its name to 10X Genomics, Inc. in March 2015. The company offers chromium single-cell gene expression solutions, chromium single-cell immune profiling solutions, chromium single-cell CNV solutions, chromium single-cell ATAC solutions, chromium genome solutions, chromium exome solutions, and chromium de novo assembly solutions.

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Illumina, Inc.

Established in 2000, Illumina, Inc. is headquartered in California, the U.S. The company is a global life science company engaged in the development and commercialization of genetic analysis solutions covering the areas such as sequencing, genotyping, and expression. The company operates its business through two major segments: Core Illumina and the consolidated variable interest entities (VIEs), which include the activities of GRAIL, Inc. (GRAIL) and Helix Holdings I, LLC (Helix). Core Illumina consists of Illumina, Inc.’s core operations. Core Illumina's products and services serve customers in research, clinical, and applied sectors and enable the adoption of a wide range of genomic solutions. The company provides whole-genome sequencing, genotyping, NIPT, and support services. The company's technology platforms support the scale of experimentation required for population-scale studies, genome-wide discovery, target selection, and validation studies.

Dovetail Genomics LLC

Founded in 2013, Dovetail Genomics LLC is headquartered in California, the U.S. The company’s business line includes providing commercial, physical and biological research and development services. The company is involved in de novo assembly, structural variation, microbiome analysis, cancer research, phasing analysis, and comprehensive view of genomes. In 2018, the company introduced its first commercial service for analysis of human genomes.

Global Spatial Genomics & Transcriptomics Market – Dynamics

Drug discovery and disease identification a key driver

Increasing awareness about disease management and drug discovery drives the global spatial genomics & transcriptomics market. Disease management and drug discovery are the most rapidly expanding application segments of the market. The rise in genome knowledge has led to increased research in several, rare, genetic and oncology diseases. Also, the increasing demand from diagnostics in neurology and immunology as well as other areas of biology has been significantly driving the market. Personalized medicine and companion diagnostics are significant add-on part responsible for growth of the global spatial genomics & transcriptomics market. According to a magazine called Labtimes, over 700,000 genetic tests are performed in Europe every year and over 30 million people suffer from some form of a genetic disorder. Spatial genomics technology bridges microscopy and RNA sequencing to generate complete transcriptome data from a single intact tissue sample and utilizes standard instrumentation for sequencing already present in most labs, allowing for barrier-free adoption.

Increased investments in genomics

With increasing investment in spatial genomics & transcriptomics along with expanding supporting growth from investors are expected to offer the greatest market attractiveness in terms of revenue. Certain countries do have challenging entry barriers in terms of political and legal framework clearance. However, with increasing awareness and adoption, the market penetration is expected to offset the entry barriers. Government funding and support and collaborative research with large pharmaceutical players are estimated to be significant drivers of this market in the near future. For instance, in January 2019, 10X Genomics received a combined funding of US$ 243 Mn, of which US$ 35 Mn was an extension of 10X Genomics Series-D financing. 

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Spatial Genomics and Transcriptomics Market Report 2022 to 2030 By Top Key Players, Types & Applications

The Spatial Genomics and Transcriptomics Market size was $163.8 million in 2020, and is expected to grow at a value of more than $470.55 million by 2030, registering a CAGR (Compound annual growth rate) of over 11% from 2022 to 2030.

Due to the rising potential of spatial genomic analysis as a cancer diagnosis tool and the arrival of the fourth generation of sequencing, the market for spatial genomics and transcriptomics will experience significant expansion. A desirable novel biomarker needed in many cancer types is genome placement. The use of spatial information as a diagnostic biomarker for many diseases was made possible by the discovery of spatial patterns in the genome for a number of medical problems. Biomarkers that enable more accurate classification between benign and malignant tumours are in increased demand. The need for spatial genomics analysis as a cancer detection tool is increasing as a result of this factor.

A research created by FutureWise Industry Research offers a thorough analysis of the market trends for spatial genomics and transcriptomics that will impact the expansion of the overall market. Additionally, it has comprehensive details on the profitability graph, SWOT analysis, market share, and regional expansion of this company. The study also provides information on the current status of important market participants in the examination of this industry's competitive landscape.

Spatial Genomics and Transcriptomics Market: Segmentation Analysis

Spatial Genomics and Transcriptomics Market by technology:

·         Spatial transcriptomics

Sequencing based methods

§  Laser capture microdissection

·         FFE tissue samples

·         Others

Transcriptome in-vivo analysis (TIVA)

In situ sequencing

Microtomy sequencing

·         IHC

·         Microscopy based RNA imaging techniques

Single molecule RNA fluorescence in-situ hybridization

Padlock probes/rolling circle amplification

Branched DNA probes

·         Spatial genomics

FISH

Microscopy-based live DNA imaging

Genome perturbation tools

Massively-parallel sequencing

Biochemical techniques

Others

The spatial transcriptomics section ruled the market with a revenue share of more than 80% in 2020 attributable to its high reception when contrasted with spatial genomic techniques for the transcriptomic study of single cells. The development of this section can likewise be ascribed to the accessibility of automated sequencing philosophies, for example, laser catch microdissection technique (LCM), to fulfil the growing need for nucleic acid sequencing of biological specimens or single cells.

Spatial Genomics and Transcriptomics Market by workflow:

Spatial imaging

Spatial analysis

Spatial sequencing.

Spatial Genomics and Transcriptomics Market by product type:

·         Instruments

By mode

§  Automated

§  Semi-automated

§  Manual

·         By type

Sequencing platform

IHC

Microscopy

Flow cytometry

Mass spectrometry

Others

·         Consumables

·         Software

Bioinformatics tools

Imaging tools

Storage and  management databases

Among these, Consumables Segment is expected to witness healthy growth during the forecast Period. The section is projected amplify substantially because of the rising occurrences of various chronic disease and cancer cases across the globe. Inferable from an increment in the rising rates, increasing R&D development are likely to push the market progression.

Spatial genomics and transcriptomics market by application: 

Translational research

Drug discovery & development

Others

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Top Key Players:-

Akoya Biosciences, Inc.

BioSpyder Technologies Inc.

Bio-Techne Corporation (Advanced Cell Diagnostics, Inc.)

Dovetail Genomics, LLC

Fluidigm Corporation

Genomic Vision SA, Illumina, Inc.

Lunaphore Technologies SA

Nanostring Technologies, Inc.

Natera Inc.

PerkinElmer Inc. (Horizon Discovery Group Plc.)

Rarecyte, Inc.

Rebus Biosystems, LLC

Resolve Biosciences

S2 Genomic

Seven Bridges Genomics

Singular Genomics System, Inc.

Tecan Group Ltd. (Nugen Technologies, Inc.)

Ultivue, Inc.

Veranome Biosystems LLC

Vizgen Corporation

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