#Haemophilia Treatment Growth

[market-spy]

Regenerative Medicine Market Forecast to Grow at 27.2% CAGR from 2024 to 2031 | SkyQuest Technology

SkyQuest projects that the global Regenerative Medicine Market will attain a value of USD 83.6 billion by 2031, with a CAGR of 27.2% during the forecast period (2024-2031). The basic goal of regenerative medicine is to restore function that has been compromised by any cause. Regenerative medicine can repair or replace tissues and organs damaged by aging, disease, or trauma, as well as normalize congenital abnormalities. Additionally, it helps reduce inflammation and stop the growth of scar tissue. In addition, some promising methods, such as endogenous stem cell stimulation and organoid transplantation to heal small tissue injuries, will drive market growth in the coming years.

Download a detailed overview:https://www.skyquestt.com/sample-request/regenerative-medicine-market

Cell Therapy to Dominate the Market Share by Offering Early Clinic Applications

The cell therapy segment is the largest segment in the regenerative medicine market and is accounted for the highest revenue share. This dominance is expected to continue throughout the forecast period. Primary cell-based therapies are the most developed medicines accessible due to their use for various therapeutic purposes and early clinical applications. The stem cell and progenitor cell-based therapeutics segment is growing, owing to significant investments in stem cell research and changes in regulatory rules to allow for their use in clinical applications.

Gene Therapy Segment to be the Fastest Growing Due to Increase in Investments in Gene Therapy

The gene therapy segment is the fastest growing segment in the regenerative medicine market by product. The advancements in gene technology provide precise correction of genetic defects which contributes to segmental growth. It offers long-lasting solutions for conditions such as haemophilia, muscular dystrophy, and others. The increase in the investments in gene therapy is driving the expansion of the market growth.

North America is the Leading Consumer Due to the Presence of Major Market Players

North America is the largest region in the global market, accounting for more than 45% of the total revenue. This is due to the presence of many major players in the US. The presence of research institutions interested in developing innovative treatments and the availability of advanced technologies contributes to many clinical trials in the region. Financial availability, as well as many initiatives by government and private organizations, contributes to the largest revenue stream from the United States.

Regenerative Medicine Market Insights:

Drivers

Rising Incidence of Chronic and Genetic Diseases

Advancements in Genomic Technologies

Patient-Centric Approach and Preventive Medicine

Restraints

High Cost of Regenerative Medicine Technologies

Data Privacy and Security Concerns

Interpretation Difficulties and Clinical Relevance

Prominent Players in Regenerative Medicine Market

Illumina, Inc.

Thermo Fisher Scientific Inc.

Novartis AG

Abbott Laboratories

Agilent Technologies

Almac Group

Amgen Inc.

Astellas Pharma Inc.

AstraZeneca PLC

Bio-Rad Laboratories, Inc.

Key Questions Answered in Regenerative Medicine Market Report

Which are the primary factors propelling the growth of the Regenerative Medicine Market?

What factors are supporting the growth of the Regenerative Medicine Market?

What role does research institute plays in North America's dominance in the global market for Regenerative Medicine?

This report provides the following insights:

Analysis of key drivers (growing demand for better data security, rising adoption of Blockchain and IoT technologies, increasing use of decentralized systems in different industry verticals), restraints (interoperability issues with legacy systems, complexities in integration with existing infrastructure, concerns regarding scalability of gas cleaning technologies systems), and opportunities (growing demand for data monetization, rising demand for transparent yet trusted transactions), influencing the growth of regenerative medicine market.

Market Penetration: All-inclusive analysis of product portfolio of different market players and status of new product launches.

Product Development/Innovation: Elaborate assessment of R&D activities, new product development, and upcoming trends of the regenerative medicine market.

Market Development: Detailed analysis of potential regions where the market has potential to grow.

Market Diversification: Comprehensive assessment of new product launches, recent developments, and emerging regional markets.

Competitive Landscape: Detailed analysis of growth strategies, revenue analysis, and product innovation by new and established market players.

About Us:

SkyQuest is an IP focused Research and Investment Bank and Accelerator of Technology and assets. We provide access to technologies, markets and finance across sectors viz. Life Sciences, CleanTech, AgriTech, NanoTech and Information & Communication Technology.

We work closely with innovators, inventors, innovation seekers, entrepreneurs, companies and investors alike in leveraging external sources of R&D. Moreover, we help them in optimizing the economic potential of their intellectual assets. Our experiences with innovation management and commercialization have expanded our reach across North America, Europe, ASEAN and Asia Pacific.

Contact:

Mr. Jagraj Singh

Skyquest Technology

1 Apache Way,

Westford,

Massachusetts 01886

USA (+1) 351-333-4748

Email: sales@skyquestt.com

Visit Our Website: https://www.skyquestt.com/

[actu24hp]

Roche warns of lower results in 2023

BASEL, Switzerland (Reuters) – Swiss pharmaceutical group Roche warned on Thursday of a decline in its results in 2023, as sales growth in drugs such as the haemophilia treatment Hemlibra and one against sclerosis plates Ocrevus will not offset the decline in demand for COVID-19 related products and diagnostic tests. Roche therefore expects consolidated sales at constant exchange rates and core…

[blogaarti]

Bruise Treatment Market Insights, Growth and Investment Feasibility By 2029

Bruises are a common occurrence, and they occur usually after a trauma injury. Bruise forms after the blood vessels under the skin get injured, thereby trapping the blood underneath and creating a black, purple, or blue mark. Besides blunt trauma, the growing prevalence of blood-related health disorders such as haemophilia, leucocytosis, Von Willebrand disease, and anaemia are some of the common causes of bruising. As per data provided by the Centres of Disease Control and Prevention (CDC), over 1 in every 5000 males is expected to develop haemophilia. This medical condition is also known to affect all ethnic groups and races. Moreover, growing awareness of health and fitness is increasing people’s interest in sports activities and workouts. Such a lifestyle can increase the chances of injuries such as sprains. All these factors are collectively nurturing favourable conditions for the growth of the global bruise treatment market.

 For More Industry Insight Read: https://www.fairfieldmarketresearch.com/report/bruise-treatment-market

 Growing Prevalence of Blood Disorders to Maintain Positive Growth Curve for Bruise Treatment Market 

The growing incidence of blood disorders such as anaemia, haemophilia, leucocytosis, and Von Willebrand disease has created a significant healthcare challenge. In turn, this is spiking the number of bruises across the globe. Several anticoagulant and anti-inflammatory bruise treatment medications are growing in demand. Moreover, disorders such as haemophilia can hamper appropriate natural clotting of blood which can result in constant bruising of the patients. In addition, the Von Willebrand disease in the ageing population is also contributing to this healthcare challenge. All these factors are expected to be some of the key drivers of the global bruise treatment market expansion in the future.

 Development of More Potent Anti-inflammation Bruise Medications to Boost Growth Prospects of Bruise Treatment Market 

A bruise by itself is not a particularly serious medical condition, mainly due to the high availability of bruise medications. Modern bruise medications significantly limit the chances of developing infections on bruises. Yet, most bruises can be a cause of inflammation due to high trauma on nerves. Moreover, critical inflammation can still lead to complexities and discomfort. Against this backdrop, soaring demand for anti-inflammation bruise treatment medications is emerging as a notable growth prospect. Simultaneously, nonsteroidal anti-inflammatory drugs (NSAIDs) are also growing in demand as they help with sprains, headaches, and painful menstruation. These developments are providing impetus to the global bruise treatment market.

 North America to Lead Bruise Treatment Market Owing to High Prevalence of von Willebrand Disease 

The growing geriatric population, high incidence of haemophilia, and greater healthcare awareness are aiding the growth of the bruise treatment market across North America. Moreover, the cases of disorders such as Von Willebrand disease are also increasing in the region. The presence of a robust healthcare infrastructure in North America is expected to maintain the region’s leading position in the market. The regional pharmaceutical and biotechnology players are constantly investing in advanced bruise treatment R&D. All these factors are boding well for the regional bruise treatment market.

Key Market Player 

The most competitive players participating in the global bruise treatment market include TriDerma, Bioderma, Arnicare Boiron, Pharmavite LLC, Stada Arzneimittel AG, Zealous Health Private Limited, and Topix Pharmaceuticals Inc.

 For More Information Visit: https://www.fairfieldmarketresearch.com/report/bruise-treatment-market

 About Us

Fairfield Market Research is a UK-based market research provider. Fairfield offers a wide spectrum of services, ranging from customized reports to consulting solutions. With a strong European footprint, Fairfield operates globally and helps businesses navigate through business cycles, with quick responses and multi-pronged approaches. The company values an eye for insightful take on global matters, ably backed by a team of exceptionally experienced researchers. With a strong repository of syndicated market research reports that are continuously published & updated to ensure the ever-changing needs of customers are met with absolute promptness.

[melbournenewsvine]

Midlothian biotechnology firm ProFactor Pharma seals game-changer deal to broaden use of low-cost Haemophilia A treatment

The Roslin-headquartered firm explains that the disorder involves not being able to make enough, or any, “Factor VIII” to stop bleeding. However, it says it has developed a proprietary cell line capable of producing Recombinant Human Factor FVIII (rhFVIII) at significantly higher yields, which when combined with a production process employing “innovative” disposable/single-use technology, delivers a low cost of goods. It has now revealed the completion of a Product Development, Technology Transfer and Licence Agreement with PT Bio Farma (Persero), which will see Indonesia’s largest pharmaceutical company and manufacturer of vaccines and other biological products scale up PFP technology to industrial level and implement clinical trials in South-east Asia and India. According to PFP, which in 2019 sealed a £2 million funding injection and counts Scottish venture capital firm Kelvin Capital as an investor, the tie-up opens an estimated $1.36bn (£1.52bn) total addressable market for treatment in India, Indonesia, Malaysia, Thailand, Philippines, Singapore, and Vietnam. The Scottish business added that under the deal, Bio Farma will make up-front and milestone payments of “several million” dollars to access its technology and royalties on sales, and comes as the Indonesian company already distributes products to 150 countries and will also supply PFP finished product for global sales. From left: John McNicol of Kelvin Capital with PFP’s CEO Jaymin Amin and board director Ian Fotheringham at the biotech firm’s offices in Roslin. Picture: contributed. PFP chief executive Jaymin Amin said: “This agreement has the potential to be a real game-changer for the treatment of Haemophilia A across the world, and significantly in the undersupplied markets in Asia, Middle East, Eastern Europe and South America that cannot afford to buy current treatments. There also is a huge undersupply of [rhFVIII] worldwide, which PFP is now well-placed to address. We will soon commence a major Series A funding round to begin human clinical trials, which will run over two to three years. Once concluded, we are confident that we will have a treatment that will be low-cost and accessible to every sufferer of Haemophilia A, no matter where they live.” Also commenting was the firm’s chief financial officer Richard Cruse, who said: “This agreement demonstrates PFP is open to collaborations with pharma companies in these underserved markets to make treatment available not only via additional volumes, but also for those locked out by high prices.” Honesti Basyir, president director of Bio Farma, said: “Collaboration with [PFP] will further maximise Bio Farma’s innovation and performance, especially related to its vision and mission to produce quality life sciences products of international standard and affordable for people in various parts of the world.” PFP cites research finding that there are 660,000-plus sufferers of Haemophilia A worldwide but only around 191,000 are currently treated, with a major challenge being a significant lack of provision in markets excluded from medications involving rhFVIII due to high prices. Kerry Sharp, director of entrepreneurship and investment at Scottish Enterprise, said: “Scotland’s life sciences sector is internationally renowned… [PFP’s] agreement with Bio Farma demonstrates how Scottish companies can drive global innovation in the pharma sector and beyond. We look forward to continuing our partnership with the company as it delivers potential growth opportunities and medical advances.” Source link Originally published at Melbourne News Vine

[techsciresearch]

North America to Dominate Haemophilia Treatment Market During Forecast Period – TechSci Research

Increasing number of haemophilic patients worldwide and increased diagnosis rate across the globe to drive global haemophilia treatment market

According to TechSci Research report, “Global Haemophilia Treatment Market By Type, By Product, By Treatment, By Therapy, By Region, Competition, Forecast & Opportunities, 2025”, global haemophilia treatment market is expected to witness significant CAGR during the forecast period. Increasing number of haemophilic patients worldwide is one of the major factors accounting for the growth of global haemophilia treatment market. Moreover, upsurge in the use of prophylactic treatment for hemophilia is expected to bode well for the growth of global haemophilia treatment market through the forecast period. In addition to this, supportive initiatives plan by governments worldwide in order to commence early screening of neonates is expected to positively influence the growth of global haemophilia treatment market in the years to come. Also, growing severity with the genetic evolution, is making headway for the growth of global haemophilia treatment market. Furthermore, rising availability of hemophilia drugs is also contributing to increasing market growth. However, there are certain factors that might hamper the growth of global haemophilia treatment market over the coming years including high cost of recombinant products, stringent government regulations and serious adverse effects associated with plasma derived products.

Browse XX market data Tables and XX Figures spread through XXX Pages and an in-depth TOC on " Global Haemophilia Treatment Market "

https://www.techsciresearch.com/report/haemophilia-treatment-market/5057.html

Global haemophilia treatment market can be segmented based on type, product, treatment, therapy, company, and region. Considering the product, the market is fragmented into plasma derived coagulation factor concentrate, recombinant coagulation factor concentrates, desmopressin, and antifibrinolytics agents. Here, the recombinant coagulation factor concentrates segment dominated the global haemophilia treatment market in terms of largest market share until 2019 and is further anticipated to maintain its dominance during the forecast period as well, which can be accredited to increase in production of recombinant factor concentrates to treat hemophilia coupled with high availability of plasma-derived concentrates. Moreover, enhanced safety of replacement therapy by using recombinant factor concentrates, is further boosting the segmental growth. In terms of treatment, the market is categorized into on-demand and prophylaxis. Out of which, the prophylaxis treatment segment is forecast to grow at a high CAGR in the years to come, on account of its efficiency and better end results. Additionally, preference for long-term prophylaxis treatment to prevent chronic arthropathy and joint bleeding in patients with severe haemophilia, is further contributing to the growth of the segment.

Novo Nordisk A/S, Shire, Chugai Pharmaceutical Co. Ltd., Bayer AG, Pfizer, Inc., CSL Behring, BioMarin, Octopharma AG, Genzyme Corporation, Spark Therapeutics, Inc., Baxter International, Inc.s, Grifols SA, Kedrion, Biogen Idec, Inc., Hospira, Incare among others are the leading players operating in global haemophilia treatment market. The players are adopting several growth strategies to enhance the market scenario of haemophilia treatment. Other competitive strategies include mergers & acquisitions; agreements, partnerships, and collaborations; and expansions to diverse their product portfolio in order to strengthen their market position.

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customers can also request for 10% free customization on this report.

“North America is forecast to dominate the global haemophilia treatment market during the next five years on account of presence of favorable healthcare reimbursement and insurance policies in the region. Furthermore, growing demand and adoption rate of haemophilia medications is also contributing to the growing trend. Additionally, better diagnostic techniques in the region is anticipated to bolster the growth of growth of global haemophilia treatment market over the coming years.”, said Mr. Karan Chechi, Research Director with TechSci Research, a research based global management consulting firm.

“Global Haemophilia Treatment Market By Type, By Product, By Treatment, By Therapy, By Region, Competition, Forecast & Opportunities, 2025” has evaluated the future growth potential of global haemophilia treatment market and provides statistics & information on market size, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges and opportunities in global haemophilia treatment market.

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[jstawowy]

Inżynieria genetyczna, 2020

Cykl Inżynieria genetyczna nawiązuje do wykorzystywania organizmów transgenicznych w medycynie w celu szerzenia wiedzy, która bywa zapominana we współczesnym świecie na rzecz bardziej popularnych, powtarzanych często informacji - często mówimy o czymś prezentując tylko jeden punkt widzenia i zapominamy (lub nie wiemy), że temat posiada również drugą stronę. Różnokształtne i różnowymiarowe obrazy mają za zadanie w sposób luźny nawiązywać do budowy substancji dających się wyprodukować z GMO na rzecz człowieka. Plakietki doczepione do prac posiadają funkcję informacyjną – są na nich zapisane informacje dot. poszczególnych leków/substancji – a także mają przypominać swoim wyglądem ceny i w ten sposób nawiązywać do rynku sprzedaży leków.

Inżynieria genetyczna ogrywa ważną rolę w leczeniu wielu schorzeń. Dużo słyszy się na temat rzekomo złego wpływu pożywienia produkowanego przy pomocy GMO na organizm ludzki, większość z nas niewiele jednak wie o tym, jak ogromne zmiany zaszły w medycynie dzięki użyciu organizmów transgenicznych. Bez inżynierii genetycznej wielu z nas nie miałoby szans na normalne życie (lub życie w ogóle).

Na liście leków produkowanych z użyciem GMO znajdziemy m.in. substancje hormonalne (hormon wzrostu, gonadotropiny, insulina), interleukiny (cząsteczki koordynujące pracę układu odpornościowego), interferony (białka zwalczające infekcje wirusowe), czynniki krzepnięcia krwi (których brak chorym na hemofilię), enzymy stosowane w terapii wrodzonych zaburzeń metabolicznych. Większość wyżej wymienionych substancji produkują dziś genetycznie modyfikowane mikroby, najczęściej bakterie – pałeczki okrężnicy (Escherichia coli) i laseczki sienne (Baccillus subtilis), czasem również drożdże Saccharomyces cerevisieae lub Pichia pastoris. Organizmy z modyfikowanym DNA produkują na nasz użytek także przeciwciała monoklonalne używane w leczeniu schorzeń autoimmunologicznych takich jak stwardnienie rozsiane, reumatyzm czy choroba Leśniowskiego-Crohna. Dzięki inżynierii genetycznej możemy wytwarzać również szczepionki z  pominięciem hodowli niebezpiecznych dla człowieka patogenów (np. preparaty przeciwko WZW typu B, wprowadzone do użytku w 1986 roku).

Insulina

Praca Insulina jest jedną z cyklu prac Inżynieria genetyczna, który nawiązuje do wykorzystywania organizmów transgenicznych w medycynie. Na plakietce przyczepionej do obrazu widnieje ciąg aminokwasów budujących łańcuchy insuliny ludzkiej, z kolei okrągłe twory na powierzchni płótna mają przywodzić na myśl kolonie bakterii E. coli na szalce petriego.

Genetic engineering, 2020

Genetic engineering plays an important role in the treatment of many diseases. We hear a lot about the supposedly bad effects of GMO food on the human body, but most of us don't know much about how enormous changes have occurred in medicine through the use of transgenic organisms. Without genetic engineering many of us would have no chance of a normal life (or life in general).

The list of medicaments produced with the use of GMO includes hormonal substances (growth hormone, gonadotropins, insulin), interleukins (molecules that coordinate the work of the immune system), interferons (proteins that fight viral infections), blood clotting factors (which are helpful in haemophilia), enzymes used in the treatment of congenital metabolic disorders. Most of the substances mentioned above are produced today by genetically modified microbes, most often bacteria  – coliform bacteria (Escherichia coli) and hay bacilli (Baccillus subtilis), sometimes also by the Saccharomyces cerevisieae or Pichia pastoris. Organisms with modified DNA also produce monoclonal antibodies used in the treatment of autoimmune diseases such as multiple sclerosis, rheumatism or Crohn's disease. Thanks to genetic engineering we can also produce vaccines without breeding pathogens that are dangerous to humans (e.g. preparations against hepatitis B).

Insuline

The artwork Insulin is one of the series named Genetic Engineering, which relates to the use of transgenic organisms in medicine. The plaque attached to the painting shows a string of amino acids that build the human insulin chains, while the round formations on the surface of the canvas are supposed to resemble colonies of E. coli bacteria in a petri dish.

[expert-market-research]

Global Haemophilia Treatment Market Is Expected To Grow Steadily At CAGR Of 5% In The Forecast Period Of 2021-2026

The new report by Expert Market Research titled, “Global Haemophilia Treatment Market Report and Forecast 2021-2026“, gives an in-depth analysis of the Global Haemophilia Treatment Market, assessing the market based on its segments like disease type, product type, therapy, end use and major regions like North America, Europe, Asia Pacific, Latin America, Middle East and Africa. The report tracks the latest trends in the industry and studies their impact on the overall market. It also assesses the market dynamics, covering the key demand and price indicators, along with analysing the market based on the SWOT and Porter’s Five Forces models.

Get a Free Sample Report with Table of Contents – https://www.expertmarketresearch.com/reports/haemophilia-treatment-market/requestsample

The key highlights of the report include:

Market Overview (2021-2026)

Forecast CAGR (2021-2026): 5 %

The increase in a number of government policies will increase the growth of the industry over the forecast period. Education and diagnostic services are provided by bodies such as the World Haemophilia Organization and governments in many countries. Government efforts to strengthen public health and treat vulnerable patients will fuel demand growth for haemophilia care in the near term. However, the high cost of haemophilia medicines will be one of the key factors impeding development. High spending, R&D, drug development and sales by manufacturers are factors that result in high drug costs. For middle-and lower-income families, high retail prices are unaffordable, limiting business growth.

Haemophilia Treatment Market Industry Definition and Major Segments

Haemophilia is an inherited medical condition that impairs the body’s ability to control coagulation or blood clotting. In this disorder, bleeding from the affected artery is poorly regulated by clotting factors; thus, coagulation does not occur.

Read Full Report with Table of Contents – https://www.expertmarketresearch.com/reports/haemophilia-treatment-market

Based on disease type, the market is bifurcated into:

Haemophilia A

Haemophilia B

Von Willebrand Disease

Others

Based on product type, the market is divided into:

Recombinant Factor Concentrate

Plasma-derived Factor Concentrate

Desmopressin

Antifibrinolytics

Others

Bases of therapy, the market is segmented into:

Replacement Therapy

Gene Therapy

Immune Tolerance Induction Therapy

Others

Based on end use, the industry can be categorized into:

Hospital Pharmacy

Retail Pharmacy

Online

Others

The regional markets for Haemophilia Treatment include:

North America

Europe

Asia Pacific

Latin America

Middle East and Africa

Haemophilia Treatment Market Trends

The global haemophilia treatment industry is rising due to the increasing incidence and seriousness of bleeding disorders, which has contributed to the development of medical knowledge and the increasing number of clinical research activities in haemophilia. Moreover, due to some factors, such as the growing use of haemophilia prophylactic medications, the discovery of novel coagulating factors, scientific advances, the booming biotechnology industry, increasing people’s awareness and increasing research and development aimed at discovering curative agents, the global market for haemophilia treatment is flourishing. Regionally, North America has dominated the industry in recent years and contributed a large market share. The rising prevalence of the disease and the preference for prophylaxis therapy are expected to be some of the drivers of regional growth. In the United States, people are suffering from this disease at a very young age.

Key Market Players

The major players in the market are Grifols SA, F. Hoffmann-La Roche Ltd, Pfizer Inc, Baxter International Inc, Bayer AG, SANOFI, among others. The report covers the market shares, capacities, plant turnarounds, expansions, investments, mergers and acquisitions, among other latest developments of these market players.

About Us

Expert Market Research is a leading business intelligence firm, providing custom and syndicated market reports along with consultancy services for our clients. We serve a wide client base ranging from Fortune 1000 companies to small and medium enterprises. Our reports cover over 100 industries across established and emerging markets researched by our skilled analysts who track the latest economic, demographic, trade and market data globally.

At Expert Market Research, we tailor our approach according to our clients’ needs and preferences, providing them with valuable, actionable and up-to-date insights into the market, thus, helping them realize their optimum growth potential. We offer market intelligence across a range of industry verticals which include Pharmaceuticals, Food and Beverage, Technology, Retail, Chemical and Materials, Energy and Mining, Packaging and Agriculture.

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[myabhijitr]

Plasmid DNA Manufacturing Market Size Is Estimated To Reach USD 2,733.8 Million with Exhibit a 23.2% CAGR by 2028 | Future Business Opportunities and Industry Insights | Cobra Biologics, VGXI, Aldevron

The global plasmid DNA manufacturing market is probably going to grow within the estimated period thanks to the growing number of patients choosing gene therapy. as an example, as of November 2017, approximately 2,600 gene therapy clinical trials were either ongoing, completed, or approved in 36 countries, per data published by the Journal of Gene Medicine in March 2018. The countries where the tests were conducted are Kingdom of The Netherlands, Switzerland, Japan, Germany, France, China, Canada, Australia, UK, US, and others. Furthermore, diseases targeted by gene therapy count neurological diseases, eye diseases, severe combined immunodeficiency (SCID), haemophilia A and B, inflammatory and infectious diseases, cancer, cardiovascular diseases, and others.

Get Free Sample PDF Copy (Including Full TOC, List of Tables & Figures, Chart) @ https://www.coherentmarketinsights.com/insight/request-sample/2593

The number of Kovid-19 infections is on the increase globally, resulting in fears of a shortage of life-saving equipment and other essential medical supplies to forestall the spread of the epidemic and supply optimal care to those affected. Furthermore, until pharmacological treatment is developed, ventilators function a vital treatment priority for COVID-19 patients who may require serious care. Currently, there’s an urgent have to accelerate the manufacturing process to develop a good range of test kits (antibody tests, self-administered and others).

Major players working within the market are specializing in the event of DNA vaccines for the treatment of COVID-19. In April 2020, INOVIO Pharmaceuticals Inc. German contract manufacturer Richter-Helm BioLogics GmbH & Co. to support production of INOVIO’s investigative DNA vaccine. Agreed to expand production partnership with KG, which is currently INO-4800. Phase 1 clinical trials for Covid-19 treatment within the US and Phase 2/3 efficacy tests within the summer of April 2020 could potentially move forward. Increasing government efforts to combat Kovid-19 will help speed up the epidemic. as an example, in March 2020, the US announced a US $ 2.9 million assistance package to India to assist the govt. of India develop laboratory systems, activate case detection and event-based surveillance, and assist technical experts in response and preparation. this is often a part of the US Global Aid Program to fight COVID-19.

Global Plasmid DNA Manufacturing Market: Drivers

The key players are specializing in various inorganic growth strategies like collaboration, which is probably going to drive growth within the global plasmid DNA manufacturing market over the estimated period. as an example, Biomay, CDMO, and BIA Separations, a number one bio chromatography development and manufacturing company, entered into a cooperation agreement to co-develop financial production systems in May 2018, for the assembly and refining of enormous DNA plasmids.

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The size of the worldwide Plasmid DNA Manufacturing Market is probably going to witness a CAGR of 23.2% during the estimated period because of the adoption of inorganic growth strategies like market share of major players, the worldwide plasmid DNA manufacturing market is probably going to grow within the estimated period. as an example, in June 2017, Alma Bio Therapeutics SAS (Alma) and Delphi Genetics expanded their strategic alliance (partnership) to develop plasmid DNA drugs. Under this alliance, Delphi Genetics created plasmid DNA for the Alma Biotherapy SAS pipeline.

Depending on the kind of product, the Plasmid DNA segment is probably going to exhibit high CAGR within the global plasmid DNA manufacturing market over the estimated period. for instance, Cobra Biologics is developing pDNA for a spread of clinical applications within the UK, in keeping with world organization (EU) clinical trials guidelines. the corporate has developed its own production process for the purification and production of pDNA, including technology associated with cell-lysis technology, operator repressor titration (ORT), and antibiotic-free plasmid maintenance systems.

In terms of the event phase, pre-clinical therapeutics is probably going to dominate the worldwide plasmid DNA manufacturing market by 2021. Increased research and development activities for the event of novel plasmid DNA are likely to extend the segmentation during this estimated period. as an example, Applied DNA Sciences Inc., the leader in large-scale polymerized chain reaction-based DNA production, announced that its wholly-owned subsidiary LineaRx Inc, specializing in next-generation biotherapeutics, has begun pre-clinical development of a non-viral, plasmid. -Free (NVPF) chimeric antigen receptor (CAR) modified T lymphocyte (CAR T) production platform available to CAR-T developers worldwide in October 2018.

Among the regions, North America is probably going to dominate the worldwide plasmid DNA manufacturing market by 2021. thanks to the presence of key players within the region, North America expects significant growth in markets that specialize in expanding facilities. Production and research and development activities. as an example, VGXI Inc. has announced the launch of a novel facility to expand its bio-production services in November 2018, including space for flexible scale plasmid DNA production still as GMP production areas for RNA synthesis.

Competitive Landscape

Key players performing in the Global Plasmid DNA Manufacturing Market are Geneone Life Science, Puresyn Inc., Altogen Biosystems, Genopis Inc., Synbio Technologies, Ajinomoto Bio-Pharma Services, Luina Bio Pvt Ltd, Greenpak Biotech Ltd, Lonza, GeneImmune Biotechnology Corp., Biomiga, Delphi Genetics, Cepham Life Sciences, JAFRAL Ltd., Biomay, Akron Biotech, Creative Biogene, GENEWIZ, Genscript Biotech Corporation, Luminous BioSciences (LBS) LLC, Vigene Biosciences, MeiraGTx Limited, LakePharma Inc., Waisman Biomanufacturing, Cell and Gene Therapy Catapult, PlasmidFactory GmbH & Co. KG, Nature Technology Corporation, Kaneka Corporation, Aldevron, VGXI Inc., and Cobra Biologics and Pharmaceutical Services*.

[accurizemarketresearch]

Global Specialty Generics Market Global Scenario, Market Size, Outlook, Trend, and Forecast, 2020 – 2030

The Global Specialty Generics Market was valued at US$ 61 billion in 2021 and is predictable to reach US$ 147.6 billion by 2030 which is projected to attain a CAGR of 10.3 % during the forecast period from 2021- 2030.

Specialty Generics are the generic versions of specialty drugs that are cost-effective compared to specialty pharmaceuticals. They can be used once off-patented for the treatment of complex & chronic health conditions which include epilepsy, multiple sclerosis, cancer, HIV, autoimmune diseases, hepatitis, rheumatoid arthritis among others.

Market Dynamics

The prime reason attributed for the market growth is due to the widespread popularity of specialty generics for the treatment of rare chronic diseases such as cancer, haemophilia, HIV AIDS among others. These are cost-effective compared to branded versions and also don’t need high-cost production & marketing. In addition, rising geriatric & aging population, rising prevalence of numerous life-threatening diseases, rise in demand from the emerging economies, and patent expiration of several branded specialty drugs are also augmenting the demand for specialty generics during the forecast period.

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Only lesser numbers of key players are available owing to its complex manufacturing requirements, relatively lower volumes, and higher capital costs are needed which results in a lower price reduction compared to traditional generics. It also requires prior authorization to order, special handling, monitoring & administration. Moreover, lack of skilled workforce, raw material sourcing, and the production of specialty generics is a complex process. Such challenges are expected to hinder the market growth of the global specialty generics market over the upcoming years. Furthermore, the advancement of cost-effective drugs for the treatment of multiple sclerosis, oncology, and other infectious diseases are expected to deliver substantial prospects for the specialty generics market expansion across the globe.

The Global Specialty Generics Market is segmented by route of administration, disease indication, distribution channel, and region. Based on disease indication, it is categorized into autoimmune diseases, oncology, infectious diseases, and others. By route of administration, it bifurcates into oral, injectables, and others. The distribution channel is bifurcated into specialty pharmacies, retail pharmacies, hospital pharmacies, and others. Based on regional insights, the global specialty generics market is categorized into North America (US, Canada, Mexico, Rest of America), Asia Pacific (India, China, Rest of Asia Pacific), Europe (UK, Germany, Russia, Rest of Europe) and Rest of the world (Latin America and Middle East & Africa).

For more information visit Accurize Market Research

[delicatemagazinedreamer]

Plasma Therapy Market Upcoming Trends, Demand, Regional Analysis and Impact of Covid-19 2028

Plasma treatment can help people live healthy, disorder-free lives by replacing missing or inadequate proteins. Human blood now provides various plasma-derived medicines for debilitating, chronic, and life-threatening illnesses as a result of improved plasma-fractionation procedures. Plasma products are essential in medical treatment and prevention. Plasma Therapy Market products are essential in the treatment of bleeding emergencies, autoimmune illnesses, and a variety of chronic conditions such as haemophilia, congenital, and acquired immunodeficiencies.

The growth in incidence of life-threatening diseases, such as chronic inflammatory demyelinating polyneuropathy (CIPD), idiopathic thrombocytopenic purpura (ITP), and multifocal motor neuropathy, is driving the Global Plasma Therapy Market (MMN). Plasma from a patient who had recovered from COVID-19 was utilised to treat another COVID-19 patient. 

Convalescent plasma has the potential to become a viable therapy option in the fight against the pandemic. As a result of the increase in demand for plasma-derived immunoglobulins for treatment procedures for COVID-19 patients with autoimmune and inflammatory illnesses, the Plasma Therapy Market for immunoglobulin is expected to grow.

Read more @ https://creativeedge16.blogspot.com/2022/01/global-plasma-therapy-market-is.html

[blogaarti]

Bruise Treatment Market Volume, Analysis, Future Prediction, Industry Overview and Forecast 2029

An alarming rise in the incidence of blood disorders such as anaemia, leukocytosis, haemophilia, and Von Willebrand Disease has become a core concern for people. Von Willebrand Disease (VWD) is a disease in which blood doesn't clot properly, causing fatal bruises. Noticeably, geriatric population is more susceptible to VWD. This has generated substantial demand for anti-inflammatory and anticoagulant drugs. In addition, with people turning toward healthier lifestyles, there has been an upsurge in physical and sports activities.  Due to intense workout sessions, individuals often develop bruises, strain, and sore muscles which need prompt treatment. As a result, there has been a momentous rise in the demand for bruise treatment. Such a landscape is fostering the ground for the global bruise treatment market to expand and grow throughout the projection period. 

For More Industry Insights Read: https://www.fairfieldmarketresearch.com/report/bruise-treatment-market

 Soaring Prevalence of Haemophilia to Bolster Bruise Treatment Market Growth Prospects

Centres of Disease Control and Prevention (CDC) recently reported that 1 in every 5000 males are likely to develop haemophilia. Among these, almost 60% of individuals suffering from haemophilia A are in a critical phase. Such an incessant rise in the prevalence of haemophilia has surged the number of bruises at a global level. Haemophilia is a rare blood disorder, wherein, due to lack of blood-clotting proteins the blood fails to clot properly. To this end, minor bumps or even minor scratches might lead to significant bruises. This puts forth the need for various drugs including anti-inflammatory and anticoagulant medications efficiently treat and heal these bruises. Against such a backdrop, the bruise treatment market is pivotally positioned to expand and prosper on the global front.

 Anti-Inflammatory Drugs to Unlock Fresh Revenue Streams for Bruise Treatment Market

The critical inflammation caused by bruises often leads to complexities and discomfort. As a result, people may feel severe pain, swelling, and redness along with loss of function. Essentially, nonsteroidal anti-inflammatory drugs (NSAIDs) help in easing pain, swelling, and other such conditions. Their ability to relieve pain, headaches, and sprains has gained notable traction in bruise treatments. That’s why these anti-inflammatory drugs are widely mentioned in post-injury prescriptions. Over-the-counter (OTC) availability of these NSAIDs has garnered tremendous popularity and boosted sales of anti-inflammatory drugs including aspirin, heparin, ibuprofen, warfarin, and clopidogrel. Against this backdrop, burgeoning sales of anti-inflammatory drugs are creating headways for the global bruise treatment expansion, generating a subsequent influx of revenue.

 North America Spearheads Growth Owing to Sustained Demand for Bruise Treatment & Growing Geriatric Population

Almost 1% of the US population is affected by Von Willebrand Disease. Approximately, 1.38 individuals per million in North America are suffering from Von Willebrand Disease type 3.  Such an alarming rise in the incidence of blood disorders and the growing geriatric population have elevated the demand for bruise treatment in the region. Furthermore, growing awareness regarding bruises and well-established healthcare infrastructure has surged R&D activities in the pharmaceutical and biotechnology domains. Under such circumstances, North America is set to scale dominance across the global bruise treatment market.

 Key Market Players

Some of the most prominent players operating in the global bruise treatment market include Pharmavite LLC, Bioderma, Zealous Health Private Limited, Arnicare Boiron, TriDerma, Stada Arzneimittel AG, and Topix Pharmaceuticals Inc.

 For More Information Visit: https://www.fairfieldmarketresearch.com/report/bruise-treatment-market

 About Us

Fairfield Market Research is a UK-based market research provider. Fairfield offers a wide spectrum of services, ranging from customized reports to consulting solutions. With a strong European footprint, Fairfield operates globally and helps businesses navigate through business cycles, with quick responses and multi-pronged approaches. The company values an eye for insightful take on global matters, ably backed by a team of exceptionally experienced researchers. With a strong repository of syndicated market research reports that are continuously published & updated to ensure the ever-changing needs of customers are met with absolute promptness.

[crimsonpublishersanatomyme]

Open Access Research in Anatomy

Do Gene and Cell Therapies will Ultimately Replace Repeated Injections for the Treatment of Chronic Diseases by Shravana Kumar Chinnikatti in Open Access Research in Anatomy

Opinion

Medical innovations are extremely important to be protected and exploited in an effective manner as they have strong social and economic impact. The potential of the gene editing tool CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) phenomenon seems to be the latest experimental use of the technology is creating skin grafts that trigger the release of insulin and help manage diabetes. This comes from the Research that has successfully tested the idea with mice that gained less weight and showed a reversed resistance to insulin because of the grafts [1]. I think this approach could eventually be used to treat a variety of metabolic and genetic conditions, not just diabetes it's a question of using skin cells to trigger different chemical reactions in the body because easy and abundantly available skin cells available at our disposal. This CRISPER is a new and innovative way of editing specific genes in the body which is responsible for a particular disease which is debilitating and by using a biological copy and paste technique: it can do everything from cut out HIV virus DNA to slow the growth of cancer cells and vice versa [2]. Any kind of disease where the body is deficient in specific molecules could potentially be targeted by this new technique. And if it works with diabetes, it could be time to say goodbye to needles and insulin injections. Any kind of disease where the body is deficient with specific molecules could potentially be targeted by this new technique. And if it works successfully with diabetes, it could be time to say goodbye to needles and insulin injections and also can be potentially be tried for the treatment of other disease like haemophilia and different cancers [3].

CRISPR-Cas9 editing of human embryos to correct an inherited form of heterotrophic cardiomyopathy (HCM) mutations in any one or multiple of these genes cause HCM [4]. Although autosomal dominant, these mutations face little selective pressure that might reduce their frequency because heart failure does not typically begin until after reproduction age. Mutations in MYBPC3 account for 40% of genetic HCM. The gene encodes the thick filament- associated cardiac myosin-binding protein C, which regulates structure of the sarcomeres in cardiac muscle [5]. This condition, however, is a common cause of sudden death among young athletes. The details of this work, published online August 2 in Nature, show the new methods avoid some of the pitfalls seen in prior attempts and would likely be safer [6]. Families with this form of HCM can use pre-implantation genetic diagnosis (PGD) after in vitro fertilization to select from the half of their embryos that do not inherit a parent's mutation [7]. If available, gene editing, which creates double-strand breaks in the DNA that permit replacement of the mutant allele with a normal (wild-type) one, would expand the pool of embryos from which to select.

Previous attempts, which introduced the gene editing (Cas9 enzyme and guide RNA) at fertilization, led to mosaic 8-celled embryos, in which some cells had the correction and some did not. Mosaic embryos would make PGD impossible and reproduction more, rather than less, risky for these couples with the new technique it completely possible to avoid mosaicism [8]. It can create fully corrected human embryos by shifting the timetable, injecting oocytes on the brink of fertilization, at metaphase of the second meiotic division, with sperm and the CRISPR components. In this sperms were from a man with a MYBPC3 4-base deletion mutation in one of the two copies of the gene (heterozygote); 12 healthy young women donated the oocytes, which had normal genes [9]. This new system used that copied wild-type gene from the oocyte. These oocytes provide the template for a natural form of DNA correction (homology-directed repair) that removes the mutant gene from the male genome and replaces it with a copy of the maternal normal gene. The DNA repair system, which is in the cytoplasm, comes from the oocyte because mature sperm have so little cytoplasm. So the introduction of CRISPR at the time of sperm injection eliminated the issue of mosaicism [10].

This new system comes with caution that, this approach for an autosomal dominant condition does not apply to an autosomal recessive condition, which is the mode of inheritance most common in young children with genetic diseases and these both copies of the targeted gene from an affected parent are mutant, an exogenous copy would need to be introduced, and that might not be safe. Adapting this technology to correct the two mutant alleles of an autosomal recessive condition could be exposing human gametes or embryos to small molecule inhibitors that could have deleterious effects on embryonic development [11].

https://crimsonpublishers.com/oara/fulltext/OARA.000509.php

For more open access journals in Crimson Publishers

Please click on link: https://crimsonpublishers.com

For More Articles on Open Access Research in Anatomy

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[lucy20kart]

Increased Government Efforts To Improve Public Awareness About Haemophilia Care Are Expected To Boost Growth In The Rest Of The World Factor Viii Deficiency Treatment Market

increased government efforts to improve public awareness about haemophilia care are expected to boost growth in the Rest Of The World Factor Viii Deficiency Treatment Market during the forecast period. To support successful haemophilia control in Australia, the NBA (National Bleeding Authority) provides money to AHCDO (Australian Hemophilia Center Directors' Organization) for haemophilia A treatment and management.

The rising prevalence of bleeding diseases, such as haemophilia, is likely to drive market growth throughout the forecast period. According to the World Federation of Hemophilia report 2018, approximately 337,000 persons worldwide suffered from bleeding problems, with 210,454 being diagnosed with haemophilia. Furthermore, according to World Federation of Hemophilia statistics from 2018, there were around 2,653 haemophilia patients in Australia, with 2,152 being diagnosed with haemophilia A.

Raed More@ https://bit.ly/3cDhQ7C

[medicswiththeo]

How Key Companies Are Shaping The Bleeding Disorders Therapeutics Market?

Bleeding disorders, also known as coagulopathy, are a group of conditions in which the blood cannot clot properly due to the missing or defective protein. Bleeding Disorder can affect a person irrespective of his genders, ages and race and the person is likely to bleed more than the average person. A minor cut or scrape may result in intense bleeding.

The coagulation factors are proteins in the blood that works with platelets and plays a vital role in the blood clot. Platelets, bound together to form the fibrin clot, and any defect in the clotting factors or platelets can lead to excessive or prolonged bleeding. Excessive bleeding during or after surgery and injury, nosebleeds, bleeding of the gums, bleeding into joints, heavy menstrual bleeding are common symptoms of bleeding disorders. It is observed that most Bleeding disorders are inherited. Still, some of the diseases may develop over time due to certain medical conditions such as deficiency of vitamin K, medications side effects, low red blood cell count, and specific liver disease.

Bleeding disorders are classified based on the types of defects such as coagulation factor deficiencies, platelet disorders, vascular disorders or fibrinolytic defects. Hemophilia A and B and Von Willebrand’s disease are common bleeding disorders due to Coagulation factor Deficiencies. As the month of March is celebrated as Bleeding disorder awareness month, we have covered some of the common bleedings disorders with key companies operating in the market to address the therapeutics challenges in their management.

Haemophilia is classified based on the missing clotting factor in the blood. Hemophilia A is one of the most common genetic bleeding disorders caused by missing or defective factor VIII, a clotting protein, due to which it is also called factor VIII deficiency.

A consists of nearly 80% of the total patient pool of Hemophilia. Hemophilia A cases are categorised as mild, moderate and severe cases based on the severity of the diseases. Further, is it observed that moderate and severe cases consist of around 75% of the patient pools of Hemophilia A. As per the Delveinisght, the total Hemophilia A prevalent population in the 7MM was 43,243 in 2020, which is expected to rise during the study period.

As of now, there is no cure for Hemophilia A. Factor Replacement Concentrates, and Bypassing agents are the major treatment option for Hemophilia A. However, at present, some of the key pharma and biotech players are exploring the potential of gene therapy for Hemophilia A. Companies such as BioMarin Pharmaceutical, Novo Nordisk, Sanofi, Pfizer, Sangamo Therapeutics, Spark Therapeutics and many others are working on novel therapeutic approaches for Hemophilia A which is expected to change the outcome for the patients affected with it. Along with the launch of the upcoming therapies, the rise in healthcare spending is expected to provide stimulus to the Hemophilia A market growth.

Hemophilia B, also called factor IX deficiency , is caused by missing or defective factor IX, a clotting protein. Haemophilia B is the second most common type of haemophilia. Being male and family history are the two main risk factors for Hemophilia B, however, in some cases, females may also show some signs of bleeding. It is genetically passed down in the family, and it may also occur by spontaneous mutation. It is found to be more prevalent in the royal families of Spain, Germany, and Russia, due to which it is also known as the “Royal disease. Like other bleeding disorders, the Hemophilia B affected person may bleed longer than other people and internal bleeding into joints and muscles and external bleeding may also occur.

According to the Delveinsight analysis, in 2020,  the total Hemophilia B prevalent population in the 7MM in 2020 was 10,739 and expected to rise by 2030. The prevalent population of Hemophilia B in the United States was observed to be 4,134 cases in 2020.

Hemophilia B lacks a permanent cure; however, treatment options such as Recombinant Factor IX Concentrates, Plasma-Derived Factor IX Concentrates, and Fresh Frozen Plasma are available in the market. At present companies such as Novo Nordisk, Sanofi, Pfizer, Sangamo Therapeutics, Catalyst Biosciences, uniQure, and others are working on different therapeutic approaches for Hemophilia B.

Von Willebrand disease is the most common bleeding disorder that equally affects men and women; however, women are likely to show more symptoms than men. As per the CDC, in the United States, around 1% of the population which is roughly around 3.2 million, is found to be affected by Von Willebrand disease. VWD is inherited from one or both parents and caused by the absence or defect in the von Willebrand factor, a protein that helps in blood clotting. The signs and symptoms of Von Willebrand disease may vary from person to person according to the severity and types. The disease largely remains unnoticed for years until the episode of severe bleeding occurs after surgery or other such procedures.

Over the past few years, increased awareness and improved diagnostics tools have played a significant role in accessing Von Willebrand disease’s burden. According to Delveinsight, in 2017, the total diagnosed Von Willebrand disease prevalent population in seven major markets was observed to be 33,758. Among the 7MM, the United States accounted for the highest diagnosed prevalence.

As per the CDC, “between 2012 and 2016, more than 14,600 men, women, and children were seen at haemophilia treatment centres for the treatment of VWD, and about 2/3 were women and girls. The current VWD treatment option is categorised into three parts based on drugs administered, which includes Non-replacement Therapy, Replacement Therapy and Adjunct Therapy. To minimise the burden of the VWD, some of the key market players, such as Shire Plc., CSL Behring, LFB Biomedicaments SA, Octapharma AG, Grifols SA and many others are working on developing Von Willebrand disease therapies. The entry of the promising expanded recombinant therapies and regulatory approvals is expected to fuel the VWD market growth during the forecasted period.

Idiopathic thrombocytopenic purpura Idiopathic thrombocytopenic purpura is another blood disorder that results in an abnormal decrease in the number of platelets in the blood which can lead to bleeding gums, internal bleeding and excessive bruising. Occurring in both children and adults, ITP can cause purple bruises. Blood in the vomit, urine or stool, nosebleeds, bruising, uncontrolled bleeding during surgery or due to cut and gum bleeding are some of the most common symptoms of ITP. Apart from bleeding, diabetes, osteoporosis, cataracts are some of the most common complications of ITP.  Idiopathic thrombocytopenic purpura is diagnosed based on the medical and medication history, physical exam and complete blood count, the blood and urine tests.

As per the Delveinsight estimations, the total Idiopathic thrombocytopenic purpura prevalent population in the seven major markets was found to be 180,498 in 2017. The current ITP therapeutics market is marked with several first- and second-line therapies. The therapeutics approach for ITP aims to provide a platelet count that prevents major bleeding rather than correcting the platelet count to normal levels. Some of the pharma giants such as Biotest, UCB Biopharma, Argenx BVBA, GC Pharma, SK Plasma, Jiangsu HengRui Medicine, Argenx, Kezar Life Sciences, Bristol-Myers Squibb, Principia Biopharma, and Protalex hold the potential to improve the dynamics of  Idiopathic thrombocytopenic purpura market with the launch of potential therapies during the forecast period.

Worldwide a significant proportion of the population is living with different bleeding disorders and creates a significant challenge in term of diagnosis and treatment. It affects the quality of life of the patients and their life expectancy. However, to address the unmet need in the treatment market companies at the global level are conducting various clinical trials to provide safe and effective therapeutic options. Similarly, some of the companies are exploring the potential of gene therapy as a treatment option for haemophilia A. Overall, in the coming years, the launch of emerging therapies, rising awareness, increasing healthcare spending, and regulatory approval is expected to address several prevailing challenges in bleeding disorder treatment and management.