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How to Determine the Best Liquid Multivitamin: A Comprehensive Guide

In today's bustling world, taking care of our health is paramount. A reliable way to support our well-being is by incorporating a high-quality liquid multivitamin into our daily routine. However, with the plethora of options available, it can be challenging to discern which product truly stands out as the best liquid multivitamin. Here, we will explore key factors to consider in order to make an informed decision.

·         Understanding the Benefits of Liquid Multivitamins

Before diving into the selection process, let's first understand why liquid multivitamins are gaining popularity. Liquid supplements offer distinct advantages over their pill counterparts, including easier absorption, faster assimilation into the bloodstream, and improved bioavailability. The liquid form allows for superior nutrient absorption, making it an ideal choice for individuals with digestive issues or difficulty swallowing pills.

·         Assessing Ingredients and Nutrient Profile

When evaluating the best liquid multivitamin, carefully scrutinize its ingredient list and nutrient profile. Look for a comprehensive blend of essential vitamins, minerals, and antioxidants that support overall health and address your specific needs. The product should provide adequate amounts of key nutrients such as vitamins A, C, D, E, B-complex vitamins, calcium, magnesium, and zinc. Avoid products with excessive fillers, artificial additives, or unnecessary ingredients.

·         Quality Standards and Manufacturing Practices

To ensure the best liquid multivitamin, it's crucial to consider the brand's quality standards and manufacturing practices. Look for products manufactured by reputable companies that adhere to strict quality control measures, such as Good Manufacturing Practices (GMP) certification. These certifications indicate that the product undergoes rigorous testing to ensure potency, purity, and safety. Additionally, prioritize brands that source their ingredients from trusted suppliers and emphasize sustainability and ethical practices.

·         Bioavailability and Absorption Rate

One of the primary advantages of liquid multivitamins is their superior bioavailability and absorption rate. Seek out products that utilize high-quality, bioavailable forms of vitamins and minerals, such as methylated B-vitamins or chelated minerals. These forms are more readily absorbed and utilized by the body, ensuring optimal nutrient delivery and utilization. Consider the presence of bioenhancers or absorption-boosting ingredients like black pepper extract (piperine) or liposomal delivery systems that can further enhance the bioavailability of the nutrients.

·         Customer Reviews and Testimonials

Another valuable aspect to consider when determining the best liquid multivitamin is to peruse customer reviews and testimonials. Online platforms, forums, and social media can provide insights into the experiences of other users. Pay attention to reviews that highlight positive results, effectiveness, and overall satisfaction with the product. However, bear in mind that individual experiences may vary, so it's crucial to consider a wide range of opinions before making your decision.

·         Consultation with Healthcare Professionals

While conducting your research, it's always advisable to consult with healthcare professionals such as doctors or registered dietitians. They can offer personalized guidance based on your specific nutritional needs, medical history, and any potential interactions with medications or existing conditions. Their expertise will help you navigate the vast array of options and select the best liquid multivitamin that aligns with your health goals.

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Does Liposomal Vitamin C Help Lose Weight Fast?

Vitamin C is popular for boosting immunity and skin health. But do you know that it can also help with fat burn? Yes, it can help you lose weight fast if you have an adequate amount of vitamin C in your body.

Vitamin C is a water soluble vitamin, and this is because it can’t penetrate fatty tissues effectively. So, it is difficult to get enough vitamin C from traditional or regular supplements. But not to worry, there is the best form of vitamin C called liposomal vitamin C, formulated using an advanced technology, i.e., liposomal encapsulation technology. Liposomes are tiny fat bubbles that are designed to carry vitamin C to the target region effectively. Liposomal vitamin C shows higher absorption (up to 95%) than regular vitamin C. And it is more than twice as effective as regular supplements.

Liposomal Vitamin C for Weight Loss

When your body has enough vitamin C, it helps promote metabolism and increase fat burning. When you workout, vitamin C increases body fat oxidation, and you lose fat fast. Therefore, people with vitamin C deficiency may not lose fat easily. Liposomal vitamin C supplements and a vitamin C-rich diet do help with weight loss fast, but it won’t help if your calorie intake is higher and you do no physical activity to burn your calories.

It’s not a good idea to take too much vitamin C. According to the office of dietary supplements, taking high doses of vitamin C may affect the absorption of other nutrients and could also cause abdominal cramps, diarrhea, and nausea. To avoid the side effects, adults should not take more than 2,000 milligrammes of vitamin C daily.

Sources of Vitamin C

1. Orange and Orange Juice

2. Red Peppers

3. Lemon

4. Grapefruit

5. Kiwis

6. Guavas

7. Kale

8. Broccoli

9. Strawberries

10. Papayas

One can get the best liposomal vitamin C supplement online at Asterveda Healthcare. We have a wide range of the best quality liposomal supplements in India.

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Top 10 Best Vitamin C Supplements For Women

Top 10 Best Vitamin C Supplements For Health

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process.

Vitamin C — also known as ascorbic acid — is an essential nutrient that plays a critical role in some of your body’s most vital functions.

Whether your goal is to give your immune system a boost or support skin health, you’re going to want to get plenty of vitamin C.

Vitamin C is a particularly unique nutrient because it also functions as an antioxidant that protects your cells against potential damage (1).

Here are the 10 best vitamin C supplements of 2020.

1. Thorne’s Vitamin C with Flavonoids

Thorne is well known for producing some of the highest quality supplements on the market, and this product is no exception.

Each capsule provides 500 mg of vitamin C and 75 mg of citrus-derived flavonoids. These compounds are found in fruits and vegetables and boast both antioxidant and anti-inflammatory benefits

Thorne’s manufacturing facilities are certified by several globally recognized third-party regulatory agencies, including NSF International and the Therapeutic Goods Administration (TGA).

All of Thorne’s supplements are tested for potency, purity, and quality multiple times throughout the manufacturing process, so you always know you’re getting a top-tier product.

Shop for Thorne’s Vitamin C with Flavonoids online.

2. Integrative Therapeutics’ Buffered Vitamin C

Price: $$

Integrative Therapeutics is a supplement company that has held a strong reputation for quality for over 3 decades.

Each capsule provides a dose of 1,000 mg of vitamin C with added minerals that may improve digestive tolerance. This feature makes it a great option for anyone with a sensitive stomach or history of difficulty tolerating nutritional supplements

Integrative Therapeutics holds itself to some of the highest ingredient sourcing and manufacturing standards in the industry, so you never have to wonder whether you’re getting a good product.

Their manufacturing facilities are certified by NSF International, a third-party regulatory agency.

Shop for Integrative Therapeutics’ Buffered Vitamin C online.

3. Kirkland Signature’s Vitamin C

Kirkland Signature provides an affordable alternative to expensive, high-end supplement brands without sacrificing quality.

Each of their vitamin C capsules contains a 1,000 mg dose of vitamin C and citrus-derived flavonoids for an added antioxidant boost.

Kirkland Signature’s vitamin C capsules are verified for purity and quality by United States Pharmacopeia (USP), so you can rest assured you’re getting exactly what the label claims.

Shop for Kirkland Signature’s Vitamin C online.

4. Best chewable: NOW Foods’ Chewable C 500

If you’re not a fan of swallowing pills, NOW Foods’ chewable vitamin C tablets may be the product for you.

NOW Foods is a reputable brand that produces a variety of affordable, high quality nutritional supplements.

Each orange-flavored tablet provides a 500-mg dose of vitamin C and contains just 1 gram of added sugar. They’re also 100% vegan and free of major allergens.

NOW Foods prides themselves on their meticulous testing protocols. Each supplement is tested in-house for purity and potency, and all of their manufacturing facilities are certified by the Food and Drug Administration (FDA).

Shop for NOW Foods’ Chewable C 500 online.

5–6. Best Gummies

Gummy vitamins are one of the hottest trends in nutrition supplements — and understandably so. Whether you’re a kid — or a kid at heart — taking your vitamin C has never been easier or more delicious.

However, although gummy vitamins are convenient and taste great, they should not be confused with candy.

It’s important that you don’t exceed the recommended dose, as too much vitamin C could lead to unintended side effects. Like other supplements, be sure to store them away from little ones to avoid a potential overdose.

5. Nordic Naturals’ vitamin C gummies

Price: $$

Nordic Naturals’ vitamin C gummies are made from high quality, natural ingredients and suitable for adults and children over the age of 4.

Each 2-gummy serving contains 250 mg of vitamin C and 4 grams of added sugar.

The orange-flavored gummies are sweetened with cane sugar and colored with natural fruit and vegetable juices. They don’t contain any artificial sweeteners or flavors and are gluten- and dairy-free.

Nordic Naturals’ vitamin C gummies are third-party tested for purity and potency, so you know you’re getting what you have paid for.

Shop for Nordic Naturals’ vitamin C gummies online.

6. Carlson Labs’ Kid’s Vitamin C Gummies

Carlson Labs’ vitamin C gummies for kids are a great option if you’re looking for a quality supplement specifically designed with your children in mind.

Each orange-flavored gummy provides 125 mg of vitamin C and contains only 2 grams of added sugar. They don’t harbor any artificial colors, sweeteners, or preservatives and are 100% gluten- and soy-free.

When it comes to quality, Carlson Labs has been an industry leader since 1965. All of their products are manufactured in an FDA-certified facility and come with a purity and potency guarantee.

Shop for Carlson Labs’ Kid’s Vitamin C Gummies online.

7–8. Best liquid

Liquid supplements are a convenient option for anyone looking for a supplement that can be easily mixed into beverages and absorbed quickly.

7. Pure Encapsulations’ Liposomal Vitamin C Liquid

Pure Encapsulations’ liquid vitamin C is made with a unique, liposomal form of vitamin C that’s encapsulated in sunflower oil.

Research suggests that liposomal forms of vitamin C may boost your body’s absorption, so you get more out of each dose

Each teaspoon (5 mL) provides 1,000 mg of vitamin C and doesn’t contain any added sugars or artificial sweeteners.

All of Pure Encapsulations’ products are certified gluten-free and third-party tested for quality, purity, and potency.

Shop for Pure Encapsulations’ Liposomal Vitamin C Liquid online.

8. Garden of Life’s Organic Vitamin C Spray

Garden of Life’s vitamin C spray is made from a variety of 100% organic, whole foods like strawberries, blueberries, and tart cherries.

You’ll receive a 60-mg dose of vitamin C in every 5 sprays, and it doesn’t contain any added sugar or artificial sweeteners. It comes in two flavors and is suitable for adults and children over 4 years of age.

The dose of vitamin C in this product is lower than many traditional supplements, making it a great option for anyone who eats a variety of vitamin-C-containing foods but still needs some extra help filling in potential nutrient gaps.

All of Garden of Life’s products are third-party tested for quality and purity, and its manufacturing facilities are FDA certified.

Shop for Garden of Life’s Organic Vitamin C Spray online.

9–10. Best powdered

Powdered supplements are a great, flexible option. Whether you plan on drinking them mixed into juices and smoothies or want to fill your own capsules with customized doses, powdered vitamin C is the way to go.

9. Swanson’s Vitamin C Powder

Swanson’s vitamin C powder contains nothing but 100% pure, powdered vitamin C.

It dissolves easily into almost any liquid, and you don’t have to worry about any added fillers, sweeteners, or preservatives.

Each scoop provides 1,000 mg of vitamin C, but you can tailor the serving size to fit your needs.

When it comes to purity and quality, Swanson holds themselves to exceptionally high standards. All of their supplements undergo in-house and third-party testing, so you can rest assured you’re getting a great product every time.

Shop for Swanson’s Vitamin C Powder online.

10. Bulk Supplements’ Vitamin C Powder

Bulk Supplements’ vitamin C powder is pure vitamin C without any added ingredients, such as preservatives, sugars, or fillers.

Each scoop provides a 750-mg dose, but like other powdered supplements, it’s easy to adjust the serving to meet your needs.

All of Bulk Supplements’ products are produced in an FDA-approved facility and third-party tested for purity and potency.

Shop for Bulk Supplements’ Vitamin C Powder online.

How to choose

Selecting the right vitamin C supplement depends on a variety of factors, including the form, quality, dose, and price.

You can start by considering how you’ll be using the supplement. For instance, if you prefer to take a pill, you’ll want to check out encapsulated vitamin C supplements.

If you don’t like swallowing pills or want to mix it into beverages, your best bet is to consider liquid or powdered supplements.

Next, you want to check the supplement’s quality. Evaluate whether a brand is reputable by exploring their ingredient sourcing and manufacturing standards. A good product will also be tested by third-party organizations, such as USP, Consumer Labs, or NSF International.

Take a look at added ingredients, too. If you’re trying to limit your intake of added sugars, you want to opt for a supplement that doesn’t contain sugar.

Another factor to consider is the dosage. The recommended daily amount of vitamin C for adults is 90 mg for men, 75 mg for women, and up to 120 mg for women who are pregnant or breastfeeding. However, certain medical conditions may require that you take much higher doses.

Children have lower vitamin C requirements, which range from 25–75mg per day, depending on their age. However, it’s not generally advised to give children a vitamin C supplement unless their pediatrician has recommended it.

Note that the Tolerable Upper Intake Level (UL) for vitamin C for men, as well as women ages 19 and above, is 2,000 mg. Meanwhile, the UL for children ranges from 400–1,800 mg, depending on age. Daily intakes at or below these amounts are unlikely to result in any adverse health effects .

Vitamin C supplements come in a wide range of dosage options. If you’re looking for a high dose, it may be more economical and convenient to find a concentrated supplement. This way you won’t be stuck consuming multiple servings of a lower dose option.

Generally, high doses of vitamin C are unnecessary and could contribute to harmful side effects. Only consume high doses if your healthcare provider recommends doing so.

Finally, you want to consider your budget. Some professional-grade brands can be expensive, but keep in mind that a higher price doesn’t necessarily mean a better product. There are plenty of high-quality options available at various price points.

Possible side effects

Although vitamin C is a natural compound, getting too much of it can cause uncomfortable and potentially serious side effects.

Some of the most common reported side effects include headaches, flushed skin, nausea, and vomiting.

Consuming high doses of vitamin C for prolonged periods may also increase your risk of kidney stones .

Always consult your healthcare provider prior to adding any nutritional supplement to your routine.

The bottom line

Vitamin C is an essential nutrient that plays a diverse role in keeping your body healthy.

Although vitamin C deficiency is rare in developed countries, it can cause serious health problems that, if left untreated, could be fatal.

If you have trouble getting enough vitamin C from your diet, supplements are a great option. They come in a variety of physical forms, dosages, and price points.

Always consult your healthcare provider prior to adding any new supplements to your health and wellness regimen.

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Buy Online R- Alpha Lipoic Acid

Alpha Lipoic Acid skin items aren't a staple of each magnificence schedule. This Universal Antioxidant doesn't have Vitamin C status in the magnificence passageways. Before long you'll be seeing green (in respect to the verdant greens in which Alpha Lipoic Acid normally happens) in the skincare segment. Dermatologists like Dr. Nicholas Perricone have been reading the supplement for quite a long time, coming full circle in the arrival of topical Alpha Lipoic Acid serums. It is anything but a craze or a marvel fixing. Alpha Lipoic Acid healthy skin advantages are genuine, science-supported, and complex. To buy online R-Alpha Lipoic Acid you will get many websites.

Alpha Lipoic Acid is ground-breaking cell reinforcement

"What I believe is interesting is its capacity to help relieve atrophic changes in the skin, for example, creepy or dainty skin," says Jennifer Mills, an esthetician in New Orleans who uses Alpha Lipoic Acid skin items and prescribes them to her customers. She began taking the item for circulatory strain support; however then saw the impacts on her skin the vast majority of which come from its cancer prevention agent capacities.

The advantages of cancer prevention agents are in invalidating the harm of free radicals, which have been embroiled in rashly maturing skin. Along these lines, it's basic to comprehend the free extreme hypothesis of maturing. Pubmed is loaded up with logical language, however here's an increasingly available clarification. Think about a free extreme like a zombie, however rather than minds it's insatiable for electrons.

It goes this way. You're a solid cell, loaded with electrons, protons, and neutrons. You're tending to your very own concerns, carrying out your responsibility to keep this general public of a body working. At that point this precarious, hungry atom appears, missing an electron like a zombie is feeling the loss of a working hippocampus. It needs your electron.

So it does what any zombie does and assaults you to take it, and when you lose that electron, you become precisely like the free radical. You join the crowd. You assault different cells and take their electrons, until there's an apoptosis pestilence and the body turns into the site of a free extreme zombie end of the world.

In the skin, free radicals can harm collagen, prompting untimely loss of versatility. They can cause hyper pigmentation and undesirable textural changes. You know zombie skin. Furthermore, they originate from all over: sustenance, liquor, contaminants noticeable all around (like tobacco smoke), and even the sun.

Things being what they are, how would you stop the eager for electron crowd from assuming control over your body? Fortunately, nature has a superior answer than any of the researchers in any zombie end of the world film: Antioxidants. These atoms have an additional electron that they give to the free radical before it can destabilize solid cells. Presently, if there was just a race of people brought into the world with two minds, one of which they could give to satisfy the zombie.

Alpha Lipoic Acid is such an incredible cell reinforcement since it is both water-and fat-solvent, so it battles free radicals in pretty much every tissue in the body. It can likewise energize different cell reinforcements — like healthy skin staples Vitamin C and Glutathione — after they've given their additional electrons. Alpha Lipoic Acid healthy skin items advantage you by alleviating the falling harm brought about by free radicals in the skin.

"ALA shields polyunsaturated fats from free extreme harm, avoiding oxidized fats, lipid peroxides, from framing," says Mills, LE, and A.A. Kinfolk. "Tobacco smoke for example, causes degenerative consequences for the skin. Alpha Lipoic Acid can alleviate those wounds through cancer prevention agent pathways. On the off chance that these progressions can happen with harmed skin, think about the progressions that can happen in a sound epidermis when Alpha Lipoic Acid is utilized as a prophylactic."

In the epidermis, the external layer of the skin, free radicals can aggregate from presentation to daylight. In a recent report, dermatologist Nicholas Perricone, MD, found that topical Alpha Lipoic Acid skin cream helped the presence of sun-harmed skin. Wrinkles and loss of skin solidness begins in the dermis, the center layer of the skin since that is the place the collagen is. What's without more radicals aren't the main risk to this significant auxiliary protein.

Alpha Lipoic Acid averts AGE development

AGEs are Advanced Glycation End Products that development in the skin as a side-effect of sugar digestion. Since we have an entire article about their consequences for the skin, we won't dive into a great deal of detail here. Simply realize that when the happen in the skin, they move generally in the dermis where they solidify collagen filaments and bargain their capacity to recover. This prompts wrinkled, listing skin. Gracious, and AGEs additionally slaughter the cells that that produce collagen.

Before anybody pondered Alpha Lipoic Acid healthy skin benefits, the supplement was principally used to help sound glucose digestion and insulin affectability. It likewise represses Glycation and the arrangement of AGEs.

Alpha Lipoic Acid advances glutathione generation

In the event that you've investigated skin lighting up, you think about "the ace cancer prevention agent" Glutathione. It very well may be successful when connected topically to the skin, however then you pass up all the supplement's advantages to the liver, the muscles, and extremely all aspects of the body. It's additionally a famously troublesome supplement to get from eating routine or supplement, which we clarify in detail in another article. Various examinations affirm that Alpha Lipoic Acid incites cells to create more glutathione, so enhancing with Alpha Lipoic Acid can enable you to understand the advantages of the two supplements.

Topical or ingestible Alpha Lipoic Acid skin items?

Both! Topical creams and serums are incredible for tending to skin tinge as they dependably enter the external epidermis. Immovability, then again, depends on sufficient collagen which is packed essentially in the dermis, the center layer of the skin. Topical supplements regularly don't enter the dermis.

The most dependable path for a supplement to arrive at the dermis is through the circulatory system. In this way, in case you're progressively worried about relieving free extreme harm in the dermis or restraining AGEs in collagen, an oral Alpha Lipoic Acid enhancement is the best approach. It's additionally the best way to get the various advantages of Alpha Lipoic Acid that run further than the skin, however contribute altogether to by and large wellbeing that is constantly obvious outwardly.

This issue with Alpha Lipoic Acid enhancements however is exactly what makes it such ground-breaking cell reinforcement: it's both pulled in to and repulsed by water. That makes it powerless to quick discharge from the body.

When you take standard oral Alpha Lipoic Acid enhancements, assimilation is fast yet deficient. Its half-life in plasma is a negligible 30 minutes. Fundamentally, some of it is consumed, however a great part of the supplement is discharged before it can get to the cells. Analysts state that Alpha Lipoic Acid seems to utilize a Na+ - subordinate multivitamin transporter to go from the blood plasma into tissues. These transporters are in constrained supply, so if an ALA atom can't get a brisk lift, it's reasonable bound for discharge.

Our Lypo-Spheric® Alpha Lipoic Acid is exemplified in liposomes that transport the supplement from the stomach related framework, through the intestinal divider and into the circulation system and the cells without depending on rare multivitamin transporters. The phospholipids that make up the liposomes are a similar material that establishes your cell layer, so the liposome can slip into the cell. That fat-based creation keeps the Alpha Lipoic Acid atoms unblemished through the fluid locales of the body since you recognize what happens when you attempt to blend oil and water. You can also prefer Lypo Extract website to buy online R-Alpha Lipoic Acid. It is well known for quality services.

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8 Key Vitamins for Beautiful Skin and Optimal Health

There are many vitamins your skin and your body need to be healthy and vibrant. In this article I will focus on 8 key nutrients.

Your skin is a reflection of your overall health and well-being.

The vitamins and nutrients that will help your skin look it’s best also make the rest of your body work its best. What’s good for the skin is good for the rest of the body and vice versa. If your skin is showing signs of aging, this is more than an issue of personal vanity. External aging and internal aging are intimately related. Poor skin can be a sign of poor health.

So today I want to talk a bit about the intimate relationship between your skin and the rest of the body. Along the way we will cover some steps you can take to turn back the hands of time, reverse the effects of aging, and get that younger, tighter, glowing skin you’ve always dreamed of.

Skin Science 101

Your skin is one of the largest and most important organs in your body. Unfortunately, most of us simply don’t give our skin the support it needs so it can function at its best.

You see, the cells in the outer layer of your skin—the epidermis—divide continuously, which means they need a lot of nutritional support. The deeper layers—the dermis—are made up of the collagen and elastin proteins, which also need plenty of support and are often undernourished by the standard American diet and lifestyle.

Skin aging is a complex biological phenomenon that consists of two independent and biologically distinct processes: intrinsic aging and extrinsic aging.1

Intrinsic aging, as its name suggests, comes from within. It is the type of damage that affects any cell in the body. One of the primary causes are free radicals which cause oxidation (rusting) of cell membranes, DNA, and so on. To combat this type of oxidative damage, it is recommended you eat a plant-based diet rich in natural antioxidants. And, as so many of us are depleted of these natural antioxidants, supplementation can help as well.

Extrinsic aging is aging from without and refers primarily to “photo-aging”: the result of exposure to outdoor elements such as ultraviolet (UV) irradiation. Photo-aged skin often shows up as the classical age-related changes we all think of: deep wrinkles, sallow discoloration, and irregular pigmentation.

Photo-aging occurs because UV light from the sun is divided into UV-A and UV-B. UV-A damages the deeper layers of the skin while UV-B causes sunburns on the outer layers. Collagen in the deeper layers of the skin can also be damaged by enzymes called “metallo-proteinases” which are turned on by UV sunlight. Oxidation plays an important role in the way that UV light damages the skin, doubling your need for the crucial antioxidants that reverse this process.

Topical agents typically focus on antioxidant support to reduce the damage from sun and elements. This can help mitigate extrinsic aging. But having an antioxidant rich diet and supplementing properly takes this all a very big step further. Taking these additional steps can help both intrinsic and extrinsic” aging, giving you more bang for your buck.

So to get the most out of your anti-aging program, here is what I recommend:

Consume large amounts of richly-colored vegetables as close as possible to their original uncooked raw form. Richly-colored plants contain phytochemicals of which many are potent anti-oxidants.

Use sunscreen. This helps protect your skin from the effects of UV light.

Don’t smoke.

Consume moderate amounts of alcohol.

Supplement

When it comes to supplementation a great way to kick start your program is to try and IV infusion designed enhance collagen synthesis and protect your skin, like the Skin and Collagen IV Treatment at our clinic in Newport Beach, CA. It also provides your body a fast replacement of the nutrients your skin needs. This helps stop and reverse the aging process. Once your base levels of these nutrients are remediated, you can maintain them with oral Liposomal Vitamin C, Liposomal Glutathione and other supplements discussed in this post (see below).

There are a few key nutrients that play a crucial role in skin health. You should consider the following as you are creating a supplement plan for your skin and your overall health.

8 Key Skin Nutrients:

1. Vitamin A (retinol—the active form of Vitamin A)…

Vitamin A is required for maintaining many essential physiological processes in the body including normal growth and development, normal vision, a healthy immune system, normal reproduction, and healthy skin and barrier functions. In excess of 500 genes are thought to be regulated by retinol.

Vitamin A is beneficial in the treatment of acne, “liver spots”, wrinkles and rough skin. One study showed that 0.4% retinol applied topically had promising anti-aging benefits (2)

UV light depletes the skin of Vitamin A. So it’s clear why this vitamin is part of anti-aging and skin improvement formulas.

It’s always a good idea to test your levels of vitamins, minerals and antioxidants before you begin treatment. If you are low in Vitamin A, a good way to get your retinol levels up quickly is to take 500,000 units per day orally for 3 days, 250,000 units for the next 3 days, 125,000 units for the next 3 days and then maintain on 60,000 units. You also should continue to test your Vitamin A levels periodically as this is a fat soluble vitamin and can accumulate to toxic levels. AVOID VITAMIN A THERAPY COMPLETELY IF YOU ARE PREGNANT

2. Niacinamide (B3 also called nicotinamide):

Niacinamide helps with moisture retention in the skin. Topically, applied niacinamide (also known as nicotinamide) 2-4% is also an effective skin whitener. Nicotinamide, an amide form of vitamin B3, boosts cellular energy and regulates poly-ADP-ribose-polymerase 1, an enzyme with important roles in DNA repair and the expression of inflammatory cytokines (3)

Nicotinamide shows promise for the treatment of a wide range of dermatological conditions, including autoimmune blistering disorders, acne, rosacea, aging skin and atopic dermatitis.

In particular, recent studies have also shown it to be a potential agent for reducing actinic keratoses and preventing skin cancers (4). Oral nicotinamide was also found to be safe and effective in reducing the rates of new non-melanoma skin cancers and actinic keratoses in high-risk patients.

3. Dexpanthenol (B5)

Like Niacinamide, Vitamin B5 is also important in maintaining tissue hydration. It reduces cholesterol levels and inflammation as well through the production of Acetyl CoA. B5 also regulates keratinocyte proliferation.

In a study, topical B5 5% ointment was as effective as 1% hydrocortisone treatment in mild to moderate atopic dermatitis (eczema) (5). Also, giving B5 orally may help decrease facial acne as shown in a study of 48 patients (6).

There is no known upper limit known for B5 supplementation, and there are lots of protocols online of high dose B5 to treat acne. For example, 5-10 grams per day has been shown to decrease acne as per Dr. Leung’s protocol, but this is not a published study by any means. Some are reporting it as effective as the commercial drug Accutane but without the major side effects.

However, one possible side effect of high dose B5 to be aware of is that stool will turn green (from bile dumping), and this may be accompanied by abdominal pain and bloating. An alternative protocol to the very high dose B5 is to use a smaller dose of B5 and combine it with L-carnitine. This may be particularly effective in treating oily skin problems as B5 decreases the accumulation of fat/oil in the skin and L-carnitine helps shuttle the fatty acids into the mitochondria to be used as energy.

In IV form B5 can be used in high doses of 500-1000 mg per IV once or twice per week. B5 is already one of the main ingredients in many of the treatments in our IV Vitamin Therapy Clinic and we often customize and individualize each IV infusion to the particular needs of our patient. WE can add a high dose of Vitamin B5 for example to almost any of the existing treatments if in fact we feel it is necessary.

4. Vitamin C

Vitamin C, also known as Ascorbic Acid, is a very important antioxidant known to reduce the photo-aging because it protects against UV light damage. It also plays an integral role in collagen production.

Topical Vitamin C:

• Reduces wrinkling in as little as 2 weeks

• Decreases the activity of melanocytes, which means it is an effective treatment in de-pigmentation of the skin,

• Decreases skin roughness

• Is effective only if the topical cream has a pH below 3.5 and only the L-ascorbic acid form is effective so make sure to check the ingredients.

• Is available in concentrations of 3-10%. However, many get the maximum benefit from 20% concentrations.

• Rarely can cause rash and can be applied every 8 hours. It’s half-life is 4 days.

• Is safe to use with other agents like glycolic acid, sunscreen etc.

Increased intake of oral Vitamin C is associated with decreased skin dryness. When taking oral Ascorbic Acid I recommend using Liposomal Vitamin C which is a vitamin encapsulation technology allowing up to 90% absorption.

IV infusions with Vitamin C are very easy to tolerate and have the added effect of increasing overall energy and vitality.

5. Minerals

Minerals are important in skin formation and protection. Mineral oxides (such as Zinc Oxide) absorb UV light and protect the deeper levels of skin from damage. Of the essential minerals, selenium and zinc have been studied most extensively when it comes to their impact on skin. Both appear to be important in protecting the skin from photo-aging and free radical damage (8).

Zinc stabilizes cell membranes and is important in cell division. This can help in wound healing. Zinc oxide and Zinc titanium are commonly found in sunscreens.

Selenium plays an important part in antioxidant proteins like glutathione peroxidase (PHGPx) and Thioredoxin Reductase (TDR) which protect skin cells from free radicals. Selenium is also key in recycling the master anti-oxidant glutathione. Selenium is present in many dandruff shampoo formulations as well.

6. Amino Acids

The amino acids L-lysine and L-proline are an integral part of collagen molecule and collagen forms the base layer of skin. However other branched chain amino acids (BCAA’s) and L-Glutamine may also play a role in collagen formation. UV Light exposure decreases the formation of new collagen and needs to be counteracted. Supplementing with key amino acids may help reverse this process. In one animal study (9) BCAA’s, L-Glutamine and proline administered orally were able to increase collagen synthesis which was initially decreased by using UV light exposure.

7. Glutathione

Glutathione is a major antioxidant in the body and plays a critical role in Phase II detoxification pathways in the body. This means it inactivates toxic molecules like heavy metals and makes them more water soluble, so that the kidneys can then flush them out.

Glutathione also has a reputation for skin whitening (10). Importantly, it inhibits melanin formation (melanin is the pigment in skin) by suppressing the activity of an enzyme called tyrosinase.

A 2012 double-blind study of 60 participants taking 500 mg reduced glutathione for 4 weeks saw reduced melanin production at 6 different skin sites (11). In another double-blind placebo controlled study in 2014, 30 participants used 2% oxidized (inactive) topical glutathione for 10 weeks and achieved a significantly lower melanin index (whitening) (12) To be fair however, two 2016 studies dispute the effect glutathione has on inhibiting melanin.(13,14)

While there are no current studies on the effect of IV Glutathione treatments for skin whitening, we do know that glutathione has a protective effect on skin through its antioxidant effect and it is considered safe even in very large doses—much higher than the typical 600-1000 mg IV doses used in IV clinics throughout the world including our clinic, IV for Life, in Newport Beach, CA.

Many patients report an evening out of their complexion, better skin tone and moisture after IV Glutathione treatments.

When taking glutathione orally I recommend only using Liposomal Glutathione, as plain glutathione has very poor absorption due to destruction by bile and stomach acid.

8. CoQ10

Coenzyme Q 10 (CoQ10) may have positive effects on photo-aging, wrinkles, skin spots, dryness and tumors. This is because it is a powerful antioxidant which neutralizes the free radicals induced by UV light which are thought to be a major factor that initiate the up-regulation of matrix metalloproteinases (MMPs). MMP’s are enzymes present in fluctuating levels in keratinocytes and fibroblasts in the deeper levels of skin.

MMP’s damage the collagen structure of skin and degrade it causing a wrinkled, aged look. A 2008 study of topically applied 1% CoQ10 cream found that the subjects had a significant reduction of wrinkles, and it is thought that this was caused by CoQ10’s antioxidant action. In addition CoQ10 inhibits MMP production, protecting dermal fiber components from degradation, leading to rejuvenation of wrinkled skin (15).

CoQ10 is easily absorbed by mouth and can be very helpful in energy production. It is depleted by “statins” which are popular prescription medications used to lower cholesterol and should definitely be used in conjunction with these medications. CoQ10 is also available as a intramuscular (IM) shot or as an IV infusion at our clinic IV for Life.

By eating well, and taking the right supplements (along with the other lifestyle tips noted above), you can get that glowing, beautiful skin you have always wanted, reverse the signs of aging and enhance your overall health at the same time.

References

 Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clinical, cosmetic and investigational dermatology. 2014.

2) Molecular basis of retinol anti-aging properties in naturally aged human skin in vivo.

Int J. Cosmetic Sci. 2016

3 Nicotinamide and The Skin Austrealas. J Dermatol. 2014.

4 A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention. N Engl J Med. 2015.

5 Comparative trial of 5% dexpanthenol in water-in-oil formulation with 1% hydrocortisone ointment in the treatment of childhood atopic dermatitis: a pilot study. J Drugs Dermatol. 2012.

6 A randomized, double-blind, placebo-controlled study of a novel pantothenic Acid-based dietary supplement in subjects with mild to moderate facial acne. Dermatol Ther 2014.

7 Vitamin C in dermatology. Indian Dermatol Online J. 2013

8 Linus Pauling Institute – Micronutrient Information Center http://lpi.oregonstate.edu/mic/micronutrients-health/skin-health/nutrient-index/minerals

9 Importance of amino acid composition to improve skin collagen protein synthesis rates in UV-irradiated mice Amino Acids. 2012.

10 Glutathione as a skin whitening agent: Facts, myths, evidence and controversies Indian J. Dermatol 2016

11 Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study. J Dermatolog Treat 2012.

12 Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women

Clin Cosmet Investig Dermatol. 2014.

13 Glutathione as a depigmenting agent: an overview. Int. J Cosmet. Sci 2005.

14 The Glutathione Derivative, GSH Monoethyl Ester, May Effectively Whiten Skin but GSH Does Not. Int J Mol Sci. 2016.

15 Mechanisms of inhibitory effects of CoQ10 on UVB-induced wrinkle formation in vitro and in vivo. Biofactors 2008.

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