#Anti-Asthmatic Drug

[semper-legens]

107. The Thieves of Ostia, by Caroline Lawrence

Owned: Yes Page count: 190 My summary: In Ancient Rome, young Flavia Gemina is on the tail of a mystery. With her new found friends - ex-slave girl Nubia, Jonathan the asthmatic Jewish boy, and Lupus the mute beggar - she’s trying to work out who is killing her town’s dogs, and why? My rating: 4/5

Yep, it seems that every time I read something unrelated but set in Ancient Rome, I get that hankering to reread the Roman Mysteries. If you weren't around for my posts about it last time, this is a kids' book series, historical fiction set in the first year of Emperor Titus' reign, around 79-80 CE. It follows a young Roman girl, Flavia Gemina, and her friends as they solve mysteries and slowly get embroiled in the politics and major happenings of the time. It was reasonably mature for the demographic at which it was aimed, never wanting to talk down to its 8-12 year old audience, but nonetheless presenting information in a way that was suitable for that demographic, not being too gory or including things that were too complex to get into. It was my gateway drug, not just to historical fiction, but to history in general when I was a kid. This series brought its setting alive for me in a way that I had never encountered before, and I hold it very dear to my heart. And you know what, it holds up. Sure, its prose is simple as befits a book for children, but there's an honesty to it that I really appreciate, and a complexity that suits its audience perfectly. There's a lot of these books, so buckle in - though I will be reading other stuff in between, for a palate cleanser.

Our cast of children offers a very balanced look at Roman (or, I guess, Ostian) life in this time period. Flavia is a freeborn, middle-class-equivalent girl, the 'everyman' of the setting. But Jonathan is Jewish (and Christian) and his father is not a Roman citizen, Nubia is enslaved, and Lupus is a homeless, mute orphan who we will later learn is Greek. And Flavia herself, as a girl, is hardly the most privileged in Roman society, though she still has her free, relatively high birth to fall back on. They're all children, and in one way or another they're all outcasts. It's an interesting choice to make, showing a microcosm of the diversity of people one might find in Italy at this time; Lawrence could easily have shown all the characters as being white Italians, but instead we have a mixture of people from across the Roman Empire. And there's a mix of personalities on display here too. Flavia is smart and bossy, Jonathan is morose, Nubia is quiet and empathetic, and Lupus is cheeky and exuberant. I particularly enjoy how full of character Lupus is despite being unable to talk or (in this book) communicate through anything other than gesture and mime. It's a well-rounded, well-balanced group of protagonists that will naturally invite its audience to relate heavily to at least one of them. (When I was a kid, I related to Flavia the most, though I wanted to be more like Nubia. These days, it's Jonathan.)

And much of Roman life is on display here. We get a child's crash course to a lot of concepts relating to life in this time and place, but as I said in the intro, there's nuance here. Of course Flavia is going to have compassion for Nubia, a girl her age being sold, and buy her to set her free, but it's noteworthy that Flavia isn't really anti-slavery (her family has an enslaved cook and doorman), she's just empathetic. The potential dangers Nubia faces are clear; she's explicitly sold naked, and Flavia's father Marcus uncomfortably tells her that someone might buy Nubia as a 'wife'. The implication is clear for anyone with the knowledge to see it, though the narrative never dwells there. And Marcus deflects this, too, saying that eleven or twelve is not too old for a slave - something that certainly grossed me out when I read this as a kid. Slavery is seen as a fact of life and normalised by Flavia, but the narrative makes it clear that it was an awful position for anyone to be in, and isn't itself pro-slavery, which is a good balance for this sort of historical fiction. It's a mature approach for a series intended for 8-12 year olds, and I commend it for that the same way I commend Animorphs or Jacqueline Wilson's books for the same things.

The one thing that's really giving me pause when I look back on it is this series' treatment of Christianity. Now, this is 79 CE - Jesus Christ is just fading out of living memory, and the Roman authorities are not big fans of the cult of Christianity. Jonathan's family is Christian, but as is historically accurate, they're Jewish as well. In later books, we see them celebrate Jewish holidays and pray in a Jewish fashion, they just follow Jesus Christ as well. Christianity has not yet diverged into how we would recognise it today. Our earliest sign that Jonathan's family is Jewish is when they're eating at Flavia's house - they're served snails, and Jonathan's sister Miriam asks their father Mordecai if it's permitted. The thing is that the series seems to want to push Christianity in a way that's a little uncomfortable for me in the present day. It's not something child!me would have noticed - I am a Christian and was raised Christian, and read a lot of books for Christian kids - but I can't help but notice how prevalent Christianity is here. Even in this early section - Flavia still follows the Roman gods, but they pray to the Christian god at one point for their sins, even if Flavia doesn't quite get the 'monotheism' thing. (She seems to treat Jonathan's god as if he's just a separate, foreign god as opposed to being The Only One like Jonathan.) It feels like it has an agenda, and it's an uncomfortable footnote in what is otherwise a great series.

Next, more Mysteries, as the kids take a holiday to Pompeii.

[vjinstrument]

Plethysmometer in Action: Real-World Applications

The plethysmometer might sound like a device straight out of a science fiction novel, but it's actually a valuable tool with very real applications across various scientific fields. Essentially, a plethysmometer measures volume changes in an enclosed space. This capability makes it incredibly useful for studying a variety of phenomena, from the breathing patterns of a lab rat to the swelling of a patient's limb.

Let's explore some of the most common and fascinating real-world applications of the plethysmometer:

1. Respiratory Research:

One of the primary uses of plethysmography is in respiratory research. By placing a subject inside a plethysmometer (often referred to as a body box), researchers can precisely measure changes in lung volume during breathing. This provides valuable insights into lung function, helping diagnose respiratory diseases like asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis.

Plethysmography can also be used to assess the effectiveness of new drugs and therapies designed to improve respiratory function. For example, researchers might use a plethysmometer to measure how a new bronchodilator medication affects airway resistance in asthmatic patients.

2. Preclinical Drug Development:

The plethysmometer plays a crucial role in preclinical drug development, particularly in evaluating the safety and efficacy of new pharmaceuticals. For instance, it can be used to:

Assess the effects of drugs on respiratory function: As mentioned earlier, plethysmography can identify potential respiratory side effects of new drugs.

Measure inflammation and edema: In studies involving inflammatory conditions, a plethysmometer can precisely measure changes in paw or limb volume in animal models, providing valuable data on the efficacy of anti-inflammatory drugs.

This data is crucial for determining whether a drug is safe and effective enough to move on to clinical trials in humans.

3. Cardiovascular Research:

While less common than respiratory applications, plethysmography can also be used in cardiovascular research. By measuring blood flow and volume changes in limbs, researchers can gain insights into vascular health and the effects of cardiovascular diseases.

4. Material Science:

Believe it or not, the plethysmometer even finds applications in material science! It can be used to measure the expansion and contraction of materials in response to changes in temperature or pressure. This information is valuable for developing new materials with specific properties, such as those used in construction or aerospace engineering.

Connecting the Dots: Plethysmometer and Pharmaceutical Production

While the plethysmometer itself is not directly involved in pharmaceutical production, the data it generates can significantly impact the development and optimization of drug manufacturing processes.

For instance, imagine a new drug being developed to treat a respiratory illness. Plethysmography data from preclinical studies can help researchers understand how the drug affects lung function. This knowledge can then be used to inform the formulation and delivery of the drug.

Furthermore, consider the role of fluid bed processors in pharmaceutical manufacturing. These machines are commonly used in processes like drying, granulation, and coating of drug particles. The goal is often to optimize these processes to create drug particles with desired characteristics for efficient drug delivery.

A fluid bed processor for granulation, for example, aims to create granules with consistent size and density. This is crucial for ensuring uniform drug release and bioavailability. While the plethysmometer doesn't directly measure these particle characteristics, the data it generates on drug efficacy can indirectly guide the optimization of processes like granulation. If a drug formulation shows poor bioavailability in plethysmography studies, it might signal a need to revisit the granulation process and adjust parameters to improve particle properties.

In conclusion, the plethysmometer is a versatile tool with a wide range of applications across various scientific disciplines. From respiratory research to material science, its ability to precisely measure volume changes provides invaluable insights that drive innovation and improve our understanding of the world around us. Although not directly used in production, it plays a vital role in the research and development of new pharmaceuticals, ultimately influencing manufacturing processes like those involving fluid bed processors.

[exim-pedia]

How to Export Medicines from India: A Comprehensive Guide

India stands as a prominent global player in the pharmaceutical industry, known for its extensive production and export of medicines. With its substantial contribution to the world's pharmaceutical needs, understanding how to export medicines from India can be both lucrative and impactful. This article provides a detailed overview of the process, requirements, and key insights into medicine exports from India.

1. Overview of India's Pharmaceutical Export Market

India is a major force in the global pharmaceutical market, contributing significantly to the production and supply of medicines. Here’s a snapshot of India’s pharmaceutical export landscape:

Global Leadership: India accounts for 20% of the world’s pharmaceutical volume and over 60% of global vaccine supply.

Export Growth: Pharmaceutical exports from India surged from Rs. 90,415 crore in 2013–14 to Rs. 2,04,110 crore in 2022–23, reflecting a remarkable growth trajectory.

Key Products: The primary products exported include formulations, biologics, bulk pharmaceuticals, and drug intermediates. Formulations and biologics alone make up approximately 73.31% of India’s pharmaceutical exports.

2. Major Medicines Exported from India

India’s pharmaceutical sector exports a wide range of medicines. Some of the most commonly exported medicines include:

Analgesics & Anti-Inflammatories

Antispasmodic Analgesics

Diuretics & Anti-Diuretics

Pro-Kinetics & Gut Relaxants

Anti-Asthmatics

Antibacterials

These medicines are essential in various therapeutic areas, including pain management, gastrointestinal health, respiratory issues, and bacterial infections.

3. Key Destinations for Indian Medicines

India’s pharmaceutical exports reach over 200 countries, with significant markets including:

United States: The largest importer, accounting for over 31% of India’s pharmaceutical exports.

South Africa

Belgium

United Kingdom

Brazil

India’s export markets also extend to the Middle East, Asia, CIS, North America, Africa, the European Union, ASEAN, Latin America, and the Caribbean.

4. Steps to Export Medicines from India

Exporting medicines from India involves several crucial steps:

Business Registration and Documentation:

Register Your Business: Ensure your business is registered with the Ministry of Corporate Affairs (MCA) and has GST registration.

Obtain an Import Export Code (IEC): Required for international trade.

Drug License: A license from the relevant Drug Regulatory Authority in India.

Certificate of Pharmaceutical Product (CPP): Required for international markets.

Product Compliance:

Get Approval from DCGI: Ensure your products meet the Drug Controller General of India’s standards.

Product Registration in Destination Country: Comply with the regulatory requirements of the importing country.

Logistics and Distribution:

Customs Clearance: Work with a customs agent to manage export documentation and compliance.

Find Distributors and Buyers: Establish connections with international distributors or buyers.

Export Documentation:

Certificate of Analysis

Letter of Credit (if applicable)

Proforma Invoice

Destination Control Statement

5. Key Export Data and Trends

2021–2022: India’s pharmaceutical exports amounted to US$ 24.62 billion, with a 1% increase from the previous year.

2022–2023: The total value of pharmaceutical exports reached US$ 25.4 billion.

Growth Rate: The export value grew by 18% year-on-year from 2020–21 to 2021–2022.

Formulations and biologics dominated the export market, representing about 75% of total pharmaceutical exports.

6. Leading Pharmaceutical Exporters in India

Some of the prominent medicine exporters in India include:

Elkos Healthcare Pvt. Ltd.

Aurobindo Pharma

Cipla Limited

Dr. Reddy’s Laboratories

Sun Pharmaceutical Industries

Lupin Limited

These companies have established themselves as significant contributors to the global pharmaceutical supply chain.

7. Why is India Famous for Medicine?

India’s prominence in the pharmaceutical industry is attributed to:

Affordable and High-Quality Medications: India is often referred to as the "Pharmacy of the World" due to its ability to produce cost-effective medicines.

Medical Tourism: India is a leading destination for medical tourism, offering advanced medical care at lower costs compared to many Western countries.

Rich Heritage in Ayurveda: India’s traditional medical system, Ayurveda, continues to be a significant aspect of its pharmaceutical offerings, particularly in the export of herbal and traditional medicines.

8. Conclusion

Exporting medicines from India involves a structured process, including obtaining the necessary licenses, complying with international regulations, and navigating logistics. With its strong position in the global pharmaceutical market, India offers substantial opportunities for businesses in the medicine export sector. By understanding the market dynamics and adhering to the required steps, businesses can successfully engage in pharmaceutical exports.

For detailed and up-to-date export data and to connect with medicine exporters, platforms like Eximpedia.app provide valuable insights and resources.

FAQs

Who is the largest exporter of medicine in India?

Elkos Healthcare Pvt. Ltd. is considered the largest exporter, alongside other significant players like Aurobindo Pharma and Cipla Limited.

What medicines are exported from India?

Major exports include analgesics, anti-inflammatories, diuretics, and antibacterials.

How to start pharma export?

Understand market dynamics, obtain necessary documentation, and comply with regulatory requirements.

Which countries buy medicine from India?

Major importers include the United States, South Africa, Belgium, the UK, and Brazil.

How many documents are required for pharma export?

Required documents include business registration, drug license, IEC, CPP, and more.

Why is India famous for medicine?

India is known for its affordable medications, rich Ayurvedic heritage, and robust pharmaceutical sector.

For more information on Ayurvedic medicine export from India or other related queries, contact Eximpedia.app for the latest global trade data and insights.

[shifahospitaltvl]

Asthma Doctors in Tirunelveli

What is Asthma?

Asthma is known to be regarded as a chronic respiratory disease which is triggered by inflammation of the airways and subsequent constriction. Some of the signs include wheezing, coughing, chest stiffness, and short breaths. Self management and control of asthma is very important in order to have a better quality of life and reduce the occurrences of the severity of the attack.

Key Treatment Options

Inhalers:

Quick-Relief Inhalers: Also known as rescue inhalers, these contain bronchodilators which work quickly to widen air passage muscles as a result of contraction. They are used during an asthma attack to help in opening up the passages as quickly as possible.

Long-Term Control Inhalers: Such inhalers have corticosteroids or other anti-inflammatory substances that bring changes to the inflammation of the bronchi, preventing the appearance of such manifestations. They are used every day in order to manage this disease, which is called asthma.

Oral Medications:

Leukotriene Modifiers: These drugs have benefit in reducing inflammation and mucus plugging of airways thus improving breathing.

Theophylline: This drug is used to prevent the muscles around the airways from contracting thus helping to open the airways for use is usually preferred for patients who do not respond to other treatments.

Lifestyle Modifications:

Avoiding Triggers: Knowing and staying away from substances that cause allergic reactions or trigger respiratory problems like ragweed, dust, cigarette smoking, and fragrances will go a long way in controlling asthma.

Regular Monitoring: Taking some tests such as visual acuity, pulse oximetry, and a lung function test that involves using a peak flow meter to monitor the severity of asthma and thus manage it appropriately.

Healthy Living: There are ways to prevent asthmatic episodes, among which are adoption of correct hygiene practices, exercise and dieting to enhance respiratory functioning.

Immunotherapy: For severe asthma due to allergies, allergen immunotherapy more commonly referred to as allergy shots may be prescribed that will gradually help to reduce the allergic sensitivity to specified allergens.

Shifa Hospital has recruited expert staff to cater for their patients. To sum up, it can be said that Shifa Hospital is one of the best options for people who want to get professional asthma treatment. Dr. Bala is a pulmonology doctor in Tirunelveli who is practicing in Tirunelveli, she has specialization in the treatment of asthma. In line with the treatment and patient care, Dr. Bala affords the necessary treatment procedures and patients with asthma also get to lead improved lives.

If you require specialized asthma management in Tirunelveli, Shifa Hospital and Dr. Bala are what you are looking for to help ease your plight and lead a healthier life again.

[hcareindia]

H & Care Incorp is a PCD pharma company in India dealing in the marketing and distributorship of pharma drugs. They provide wholesale distributorship of pharma products, with a wide range of drugs including anti-infectives, anti-diabetic, anti-inflammatory, anti-asthmatics and anti-cancer products.

Also Visit : Top 10 Pharmaceutical Companies In India 

[unibytekids]

Top Pediatric PCD Pharma Franchise Companies In India

India has a population of more than 253 million infants and adolescents. The demand for pediatric drugs in India is very high and the pediatric healthcare market is expected to grow by 6.35% CAGR during the forecast period. According to the data 5 million children under the age of 5 years of age died in 2020. Infectious diseases like pneumonia, diarrhea, malaria, premature birth, and intra-articular complications remain the top killers among children under 5 years old worldwide. The increasing number of pediatric deaths creates a demand for advanced pediatric health care and drives market growth. Unibyte Kids is a dedicated Top Pediatric PCD Pharma Franchise Company in India. 

If you are looking to start your own Pediatric Pharma Franchise in India. If you are looking to start your own Pediatric PCD Pharma Franchise business in India, then Unibyte Kids is the right choice for you. We offer a high-quality pediatric medicines range certified by ISO, WHO & GMP. Our product line includes extensive therapeutic value such as anti-worm medication, anaemia medication, Immunosuppressant and antifoaming medicines to treat various ailments in children such as Bacterial infections, Hay fever, Urticaria etc. Our manufacturing and packaging are supplied through company-owned pharmaceutical manufacturing units. We are proud to offer our associates the opportunity to start their own Pediatric Pharma Distributor business in India. With our presence across India, You can trust that our products are reliable, effective and safe. 

Top Pediatric PCD Pharma Franchise Companies In India - Unibyte Kids

Unibyte Kids is the most trusted and reliable pharmaceutical company in India for Pediatric PCD Pharma Franchise. We offer a wide variety of high-quality pharmaceuticals that are highly recommended by many well-known and experienced Paediatricians. We have links with many doctors and paediatricians who keep us informed about the increasing demand for quality medicines for kids. Our production units are well-equipped and air-conditioned. With the increasing demand, our success rate in the pediatric sector is very high. Some of the key features of our company are such as - 

Firstly our products are premium in quality and WHO, GMP, and ISO certified. 

We are working with several experts and healthcare providers. 

The franchise service is provided by the company at the PAN India Level.

Our state-of-the-art storage warehouse is conveniently located on excise duty-free and gnarly in all zones.

We have a wide range of product portfolios in the pediatric range. 

Monopoly Rights

Quality Assured Products 

24/7 Customer Supports

Quick Delivery

Wide Range and Premium Quality Pediatric Pharmaceutical Products at Unibyte Kids.

Unibyte Kids is a highly reputed and genuine PCD Pharma Franchise company that only sells high-quality products. All the products offered by the company are formulated and manufactured by the top paediatricians in the country. Since the products are intended to be used by children, we ensure that all formulations are safe to consume and have no adverse effects. Our manufacturing plants are equipped with the latest technology and machinery, allowing us to produce high-quality, safe and secure products. We offer a wide variety of products in various segments, such as:

Multivitamin Drops

Anti-allergic/Anti-asthmatic Products

Prebiotic & Probiotics Range

Rexigenic, or Appetite stimulant Medicines

Zinc Syrup

Multivitamin Syrup 

Antibiotic Syrups

Anticholinergics/antispasmodics Drops

Anti-Ulcer Medicines

Cholecalciferol/ Vitamin D3 Drops

Digestive enzymes Drugs

Anti-inflammatory Medicines

Anti-Cold & Cough Syrup

Hematinic/Folic Acid (Oral) Products

Worm Medicine (Anthelmintics)

Conclusion

One should keep some important factors by deciding pediatric PCD pharma franchise, for instance, the reputation of the company product range perks and benefits provided by the company, profit margins, etc. You can go through your gained knowledge, to choose the best and reliable Pediatric PCD Franchise company that is most beneficial for you. We can see the increasing demand for Pediatric range medicine ensures massive success in the Pharmaceutical industry.  

[zenbiotech11]

Diclofenac Sodium Sr Pellets Manufacturers

Diclofenac Sodium Sr Pellets Manufacturers

Looking for the finest diclofenac sodium sr pellets manufacturers? Look no further than Zen Biotech.

Established in 2000 by a visionary team, Zen Biotech has been dedicated to providing top-notch pharmaceuticals for a diverse range of medical applications worldwide. Our commitment to quality and consistency is unwavering, constantly driving us to enhance our standards. We proudly hold GMP certification, and WRG certification, and adhere to ISO 9001–2004 quality norms.

Our Specialization: Pellets and Granules for Various Pharmaceutical Applications

At Zen Biotech, our expertise lies in the production of pellets and granules tailored for a multitude of pharmaceutical applications. From anti-asthmatic pellets to anti-platelets, anti-malarial pellets, antifungal pellets, hyperacidity pellets, and more, we cater to a broad spectrum of medical needs.

State-of-the-Art Facility and Experienced Professionals

Backed by a cutting-edge production facility, Zen Biotech ensures that each drug meets the highest quality standards while remaining affordable. Our team of seasoned professionals is dedicated to maintaining excellence in every step of the manufacturing process.

Our Commitment to Reliability

As leading diclofenac sodium sr pellets manufacturers, we are steadfast in our mission to become a trusted name in the pharmaceutical industry. Our commitment to quality, affordability, and reliability sets us apart in delivering pharmaceutical solutions you can depend on.

For superior pharmaceutical products, partner with Zen Biotech. Contact us today to explore how our innovative solutions can meet your medical needs. 

[agexpharma-123]

Where is Benzalkonium Chloride used?

Benzalkonium chloride, also known as BKC, BAK or Alkyl dimethyl benzyl ammonium chloride, is a quaternary ammonium salt and a cationic surfactant with broad antimicrobial activity against bacterial, yeasts, fungi and viruses. It is a mixture of alkybenzydimethylammonium chloride, the alkly groups having lengths of 8 to 18.It was initially used in hard contact lens solutions but is now ubiquitous. Currently, it can be found in most topical multi-use ophthalmic preparations.

Agex Pharma which is also  a leading Dementholised Peppermint oil manufacturer in Germany manufactures benzalkonium chloride in 50% and 80% solutions as a disinfectant and preservative with excellent detergency, anti-bacterial, anti-fungal attributes.

HOW IS BENZALKONIUM CHLORIDE USED IN FORMULATIONS?

Benzalkonium chloride is widely used in inhalations, IM injections, nasal, ophthalmic, and topical preparations as an antimicrobial preservative, antiseptic, disinfectant, solubilizing and wetting agent. It is used in similarly to other cationic surfactants, such as cetrimide.

Benzalkonium chloride can also be added to topical medical devices, antiseptic wipes and cosmetics as an alternative to parabens. It produces significantly less stinging or burning compared with isopropyl alcohol and hydrogen peroxide when used in topical products.

Benzalkonium chloride solutions are active against a wide range of bacteria, yeasts, and fungi. Activity is more marked against Gram-positive than Gram- negative bacteria but minimal against bacterial endospores and acid-fast bacteria. The antimicrobial activity of Benzalkonium Chloride is greatly dependent on the alkyl composition of the mixture.

Note that benzalkonium chloride has been associated with ototoxicity when applied to the ear. Prolonged contact with the skin may cause irritation and hypersensitivity. Benzalkonium Chloride is also known to cause bronchoconstriction in some asthmatics when used in nebulizer solutions.

It is commonly used as a disinfectant in the food industry and industrial and domestic areas, but additional tests are needed before it can be used as a biocide. Aside from that, the spectrum of benzalkonium chloride usage is wide, from preservatives in certain consumer products to skin antiseptics and active ingredients in surgical disinfection. Although widely used by the industry, there is certain evidence about its toxic effects on the pulmonary system, causing ailments such as bronchoconstriction in asthmatic patients . 

 

HEALTH BENEFITS OF BENZALKONIUM CHLORIDE ?

Benzalkonium chloride is a dietary supplement that has been found to have a number of health benefits. It has been shown to help reduce inflammation, improve digestion, and boost the immune system. It has also been found to help reduce the risk of certain types of cancer, as well as reduce the risk of heart disease. Additionally, it has been found to help reduce the symptoms of allergies, asthma, and other respiratory conditions. Finally, it has been found to help improve skin health, reduce wrinkles, and improve overall skin tone.

WHAT ARE THE DANGERS OF BENZALKONIUM CHLORIDE ?

Benzalkonium chloride is a chemical compound used as a preservative in many dietary supplements. It is known to cause skin and eye irritation, as well as respiratory problems. It can also cause allergic reactions in some people, and long-term exposure can lead to liver and kidney damage. In addition, it can interact with other medications, so it is important to consult with a doctor before taking any dietary supplement containing benzalkonium chloride.

EXAMPLE PRODUCTS CONTAINING BENZALKONIUM CHLORIDE :

Antiseptic wipes, hand sanitizer, nasal sprays, throat lozenges, mouthwash, eye drops, ear drops, contact lens solution.

HOW IS BENZALKONIUM CHLORIDE REGULATED ACROSS THE WORLD?

Benzalkonium chloride is regulated differently across the world. In the United States, it is regulated as a food additive by the Food and Drug Administration (FDA). In the European Union, it is regulated as a biocide by the European Chemicals Agency (ECHA). In Canada, it is regulated as a drug by Health Canada. In Australia, it is regulated as a therapeutic good by the Therapeutic Goods Administration (TGA).

CURRENT REGULATION

In Europe, the European Commission (EC) is involved in the regulation of BACs. Recent rules in the European market included a change in the maximum residual levels of BACs allowed in food products from 0.5 mg/kg to 0.1 mg/kg, values which will undergo an additional review by the end of 2019. Additionally, recent changes in legislation, Decision (EU) 2016/1950 and the Biocidal Products Regulation (EU) no. 528/2012 (the BPR) , meant that BACs are no longer approved for use in several biocidal products, such as consumer hand and body wash antiseptics, which is in contrast with current legislation in the United States.

In the United States, the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) share the role of regulating BACs. Such agencies regularly update regulations based on current scientific data, occasionally limiting the use of compounds found not to be safe or effective. Final determinations, however, can be delayed by requests from the industry sector that commercializes such products. As an example, the FDA recently published three proposed and final decisions regarding the use of chemicals as consumer hand rub antiseptics, consumer hand and body wash antiseptics, and health care antiseptics . The rules banned specific biocides, such as triclosan, or added additional and stricter regulatory approvals for several others, such as chlorhexidine, regarding the applications mentioned above. In all instances, however, BACs were excluded from the decisions and granted deferral letters as requested by manufacturers. The decisions granted manufacturers extra time to provide data to fill gaps related to safety and efficacy. Since 2015, letters and recommendations have been moving back and forth between the FDA and manufacturers and their representatives, such as the American Cleaning Institute, Lonza America, and Henkel Consumer Goods, Inc. . Decisions to postpone any action regarding the regulation of BACs were taken based on the affirmation of lack of sufficient data in the literature. Yet, multiple researchers have studied the safety aspects of BACs over the years, which include data on the toxicity to humans and the environment, as we discuss next.

NORTH AMERICA ACCOUNTED FOR HIGHEST CONSUMPTION OWING TO RISING PRODUCT DEMAND FROM OIL &GAS SECTOR

During the historical period (2014-2019) , North America jheld the largest  benzalkonium chloride market share due to the rising opportunities for U.S. and Canadian oilfield equipment manufacturers in the region . With the increase in exploration  and production activities in the region , driven bby the rising investments in the oil & gas sector , the region i8s expected to witnmess a high volume demand  for benzalkonium chlorideand continue the trend of dominating the global industry during the forecast period.

How have we used Benzalkonium Chloride in our products at Agex Pharma?

At Agex Pharma  which is also  3-Chloro-1,2-Propanediol manufacturer in Germany our  Foam Hand Sanitiser is based on the active ingredient Benzalkonium chloride. A unique formulation featuring exceptional skin feel, conditioning and moisturising properties. The efficacy of our product has been confirmed to reduce S. aureus 99.9999% in as little as 15 seconds.

This Hand Sanitizer is in compliance with the FDA Final Tentative Monograph for OTC Hand Sanitizer preparations (leave-on sanitizers not requiring a rinse). Agex Pharma produces a fast-drying, non-sticky foam that contains unique non-drying, conditioning and moisturising ingredients- leaving the skin with a soft, refreshing and silky after-feel, and does not contain polymer thickeners or silicones.

[beautyrelay245]

Asthanil Capsules

Asthanil Asthma Capsules are used for a drug that belongs to a class of drugs called salbutamol syrup, known as bronchodilators. It is used to treat symptoms of asthma, chronic bronchitis, and other lung diseases. Ayurvedic medicine for asthma, Asthanil, contains salbutamol as its active ingredient. COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. It is an anti-asthmatic medication.

[beautyproducts24]

Asthanil Capsules

Asthanil Asthma Capsules are used for a drug that belongs to a class of drugs called salbutamol syrup, known as bronchodilators. It is used to treat symptoms of asthma, chronic bronchitis, and other lung diseases. Ayurvedic medicine for asthma, Asthanil, contains salbutamol as its active ingredient. COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. It is an anti-asthmatic medication.

[divayanshimehra]

Asthanil Capsules

Asthanil Asthma Capsules are used for a drug that belongs to a class of drugs called salbutamol syrup, known as bronchodilators. It is used to treat symptoms of asthma, chronic bronchitis, and other lung diseases. Ayurvedic medicine for asthma, Asthanil, contains salbutamol as its active ingredient. COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. It is an anti-asthmatic medication.

[revayukit]

Asthanil Capsules

Asthanil Asthma Capsule are used for a drug that belongs to a class of drugs called salbutamol syrup, known as bronchodilators. It is used to treat symptoms of asthma, chronic bronchitis, and other lung diseases. Ayurvedic medicine for asthma, Asthanil, contains salbutamol as its active ingredient. COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. It is an anti-asthmatic medication.

[beautyrelaylondon11]

Asthanil Capsules

Asthanil Asthma Capsule are used for a drug that belongs to a class of drugs called salbutamol syrup, known as bronchodilators. It is used to treat symptoms of asthma, chronic bronchitis, and other lung diseases. Ayurvedic medicine for asthma, Asthanil, contains salbutamol as its active ingredient. COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. It is an anti-asthmatic medication.

[ramlakhan0]

Asthanil Capsules

Asthanil Asthma Capsule are used for a drug that belongs to a class of drugs called salbutamol syrup, known as bronchodilators. It is used to treat symptoms of asthma, chronic bronchitis, and other lung diseases. Ayurvedic medicine for asthma, Asthanil, contains salbutamol as its active ingredient. COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. It is an anti-asthmatic medication.

[fadingfirementality]

Asthanil Capsules

Asthanil Asthma Capsule are used for a drug that belongs to a class of drugs called salbutamol syrup, known as bronchodilators. It is used to treat symptoms of asthma, chronic bronchitis, and other lung diseases. Ayurvedic medicine for asthma, Asthanil, contains salbutamol as its active ingredient. COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. It is an anti-asthmatic medication.