#mayne cord

[cloudyfacewithjam]

Paddy Mayne (Jack O'Connell) in SAS: Rogue Heroes Season 1 Episode 1

[my-scene-queen-space]

Real Name: Lauren deCamp

Scene Queen Name: Lauren Cakes/Mayne Cord

Instagram account: (@lauren.decamp)

Facebook account: (@lndecamp)

[whysojiminimnida]

Is it only me who feels like JKs singing has worsened. No, not hating just I felt so

His voice was one of my favorite. In live versions, he was infamous for singing exactly like in studio version. We have heard him singing acapellas etc very well. But in the last online concert that was not the situation. His original singing voice and the tone of singing and his stability was very much affected.

Then I thought ok Mayne he have some cold or something. But them again yesterday also it happened. Don't know if its coz he was tensed. But his singing was not the same good level. It was breathy and shaky. In both MU and Butter. Especially in MU , after Chris Martin singing JKs out of tone singing was not pleasant to hear.

I've heard him n JM saying he sings 8-10 hrs a day. He have said he wanted to find a conformable voice, in that korean variety they went on early 2021. But then his singing has worsened. I wish he take of his voice and improve it again.

Oh LORD y'all are just out here to hurt my heart today aren't you? Actually Jungkook has very close to perfect pitch. I'm often struck by how, in random VLives (i.e., his birthday) and behind videos (i.e., at the AMAs in the lot with Chris Martin) he is perfectly in tune. His voice is one of the most stable in the industry. Was he nervous at the AMAs? Yes. Wouldn't you be? Nerves account for a lot of vibrato and breath control issues that wouldn't normally be heard. So does exertion and while Koo is an incredibly stable vocalist - holding his tone and key while in aerobic-level motion - he isn't immune to those small vocal changes. You try jumping up and down twenty times and running across a hall WHILE SINGING and tell me how your voice sounds. Maybe record it. Just to give yourself a reality check. Koo actually trains his voice by singing while running for a reason. If you can do better by all means send in that Hybe audition tape. Were there serious sound quality issues, such that the boys were singing in an echo chamber, at the AMAs? Also yes. Namjoon and the others commented on it in their Live after the show, and many of us at home heard the problems with the sound. I don't feel like we can blame Jungkook personally for tech issues that mask or magnify effects and acoustics. Or for room temperature, humidity, vocal cord fatigue... I mean our boy was out there in the LA night drunk AF singing his cords off within a day of that performance. It does have effects. OMG JUST LET PEOPLE LIVE DAMN. Most artists do not have perfect pitch - many have perfect ears, they can hear even slight variations - and good or trained singers can learn to emulate the exact tone they're hearing. But perfect pitch is quite rare. Have you ever heard Ed Sheeran sing live? OMG y'all I love him but he is not it for being in tune on stage. Camila Cabello's pretty good. Ariana Grande is really good - she's very close to perfect. Gaga is in tune 99% of the time. I'd give Jeon Jungkook a 95-98 personally. And for what it's worth I believe he has a perfect ear so if he's off he can damn well hear it himself, he does not need you running your piehole to tell him. As far as vocalists go, honey, I doubt very seriously you're even in the same city as Jungkookie. His own members aren't except Jimin sometimes, all the guys are pitchy occasionally BECAUSE IT'S NORMAL AND THEY ARE HUMAN AND ALSO DANCING YOU OVERCRITICAL HOSEBAG. Don't come out here just to voice shame my baby Koo. You'll get the same backhand I reserve for Jimin antis who talk about he can't sing with zero knowledge of a whistle register or chest/head transition points. Fuck off with that nonsense. Take it back to the hater's lounge where they have ageism, racism, homophobia and now armchair vocal coaches. Boo. You're mean. Go away. Stan someone else, I hear SZA needs new fans these days. The Golden Maknae is terribly upset by your attitude while he picks up a few new awards and some endorsements and a few billion extra won ARMY and the company left lying around.

[dreamdropsystemarchive]

You don't have to reply if this makes you uncomfortable but what the heck happened to your legs? Sorry if i said it i just wanna know...

hello. im not sure if this is meant for me or Shane.... if its for me i was created without legs but i would wear bandages around my legs. where they got cut off. i was made like this. i dont know why. i was made in the mind of a child and Shane is still a child to us so its hard to know why its like this. Mayne because they want that for them

the body still has legs but causes us (mostly Shane and Sunny and I cause we front the most) a lot of physical pain (that were taking medicine for) and physical pain for Shane.

have you heard of BIID? its Body Integrity Identity Disorder. its a mental illness. heres this from the internet: BIID is a rare, infrequently studied and highly secretive condition in which there is a mismatch between the mental body image and the physical body. Subjects suffering from BIID have an intense desire to amputate a major limb or severe the spinal cord in order to become paralyzed. or blindness.

Shane is struggling with this illness. i dont have their permission to explain whats going on with them specificity cause but im sure they'd talk about it soon. its something theyve had since a child i know. and its just got worse. were actually scared they might take steps to actually have their desired body that could put the body in danger - Andy

[xalagezo-blog]

Human herpesvirus 6 encephalomyelitis. - Free Online Library

https://www.thefreelibrary.com/Humanherpesvirus6encephalomyelitis.-a0122552763 (4.) Tenembaum S, Chamoles N, Fejerman N. Acute disseminated encephalomyelitis a long-term follow-up study of 84 pediatric patients. Neurology. 2002;59:1224-31. (1.) Denes E, Magy L, Pradeau K, Alain S, Weinbreck P, Ranger-Rogez S. Successful treatment of human herpesvirus type 6 encephalomyelitis in immunocompetent patient [letter]. Emerg Infect Dis. 2004; 10:729-31. (7.) Cohen O, Steiner-Birmanns B, Biran I, Abramsky O, Honigman O, Steiner I. Recurrence of acute disseminated encephalomyelitis at the previously affected brain site. Arch Neural. 2001;58:797-801. (8.) Braun DK, Dominguez (3, Pellet PE. Human herpesvirus 6. Clin Microbiol Rev. 1997; 10:521-67. The neurotropism of HHV-6 and that the CNS may be a site of viral persistence or latency are well recognized (8,9). On autopsy, evidence of fulminant, confirms that HHV-6 causes acute CNS disease (8). Nevertheless, whether evidence of HHV-6 DNA in CSF demonstrated by PCR can be solely relied on is debatable. HHV-6 DNA was detected in the CSF of 41 (28.9%) of 142 children with a history of HHV-6 infection (9). HHV6-DNA was detected in the CSF of 47 (61%) of 77 children examined after primary HHV-6 infection. In the remaining 30 children (39%), HHV-6 DNA was detected in both peripheral blood mononuclear cells and CSF samples. HHV-6 variant A was detected more frequently in CSF than in specimens of other sites, which suggests that HHV-6A has greater neurotropism (10). The role of HHV-6 in acute multifocal neurologic disease in immunocompetent adults requires additional observation, and its role in multiple sclerosis is in question. Much can be learned from careful study of patients (1). Address for correspondence: Eric Denes, Service de maladies infectieuses, Centre Hospitalier Universitaire Dupuytren, 2 Ave Martin Luther King, 87042 Limoges Cedex, France; fax: 33-5-55-05-66-48; email: eric.denes@unilim.fr (2.) Soto-Hernandez JL. Human herpesvirus 6 encephalomyelitis [letter]. Emerg infect Dis. 2004;10:1700-1. Implicating HHV-6 in the pathogenesis of neurologic manifestations in the reported case can be challenged, as suggested by Dr. Soto-Hernandez (2). Polymerase chain reaction (PCR) results must be interpreted cautiously, especially in cases that lack corroborating clinical evidence of infection. In our case, the diagnosis was made initially when HHV-6 was found in the patient's cerebral spinal fluid (CSF) by using PCR, by the absence of other cause, and by our experience: adult CSF is usually negative for HHV-6 by using PCR. Moreover, in our case, clinical symptoms and HHV-6 in the patient's CSF evolved in the same way. The neurologic tropism of HHV-6 is well known, and the main manifestation in adults is encephalitis, especially in an immunosuppressed context. Diagnosis is usually based on finding HHV-6 genetic material in the CSF (3,4), which has now replaced brain biopsy. Positive tissue results do not distinguish latent from productive infections when PCR-positive CSF indicates viral particle production in the central nervous system (CNS). In our case, the absence of brain tissue did not allow immunohistochemical staining or in situ hybridization. In the study by Caserta et al. (5), cited by Dr. Soto-Hernandez, HHV-6 PCR was positive in CSF and negative in peripheral blood mononuclear cells in 28.9% of children [less than or equal to] 3 years old with prior HHV-6 infection. These results provide evidence of HHV-6 persistence in the CNS; this phenomenon is now well recognized. Nevertheless, HHV-6 persistence after primary infection is quite different from reactivation in an immunocompetent adult. High-avidity anti-HHV-6 immunoglobulin G detected in the patient's serum when the symptoms started proved that our patient had been infected with HHV-6 previously. * Centre Hospitalier Universitaire, Dupuytren, Limoges, France (6.) Stave O, Zamvil SS. Pathogenesis, diagnosis, and treatment of acute disseminated encephalmnyelitis. Curr Opin Neural. 1999;12:395-401. (3.) Hartung HP, Grossman Rt. ADEM: Distinct disease or part of the MS spectrum? Neurology. 2001;56:1257-60. (10). Hall CB, Caserta MT, Schnabel KC, Long C, Epstein LG. Insel RA, et al. Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A. Clin Infect Dis. 1998;26:32-7. Jose Luis Soto-Hernandez * (7.) Schwartz S, Mohr A, Knauth M, Wildemann B, Storch-Hagenloeher B. Acute disseminated encephalomyelitis. A follow up study of 40 adult patients. Neurology. 2001;56:1313-8. (5.) Caserta MT, Hall CB, Schnabel K, McIntyre K, Long C, Costanzo M, et al. Neuroinvasion and persistence of human herpesvirus 6 in children. J Infect Dis. 1994;170:1586-9. (9.) Black JB, Sanderlin KC, Goldsmith CS, Gary HE, Lopez C, Pellett PE. Growth properties of human herpesvirus-6 strain Z29.J Virol Methods. 1989;26:133-45. * Instituto Nacional de Neurologia Mexico, Mexico City, Mexico We appreciate Dr. Soto-Hernandez's suggestion concerning acute demyelinating encephalomyelitis (ADEM) in our case. ADEM is an inflammatory demyelinating disease of the CNS, occurring mostly in children and rarely in young adults, soon after an infection or a vaccination. The disease is often associated with exanthema. A virus is often thought to be the cause, but viral symptoms are often not documented and rarely treated. ADEM may evolve into multiple sclerosis, and HHV-6 has been proposed as one of the causes of that condition (6). For example, multiple sclerosis developed in 14% of children and 35% of adults with ADEM in the study by Schwarz et al. (7). I caution the casual reader who may conclude that using antiviral drugs against herpes viruses is recommended when acute mutlifocal neurologic disease clinically compatible with ADEM is indicated. High-dose IV methylprednisolone is the most utilized treatment, and the patient in the Denes et al. report was given it early in her hospital stay. The available evidence supports methylprednisolone as an essential drug in the management of ADEM. (3.) Yoshihara S, Kato R, Inoue T, Miyagawa H, Sashihara J, Kawakami M, et al. Successful treatment of life-threatening human herpesvirus-6 encephalitis with donor lymphocyte infusion in a patient who had undergone human leukocyte antigen-haploidentical nonmyeloablative stem cell transplantation. Transplantation. 2004;77:835-8. (1.) Denes E, Magy L, Pradeau K, Alain S, Weinbreck E Ranger-Roguez S. Successful treatment of human herpesvirus 6 encephalomyelitis in an immunocompetent patient. Emerg Infect Dis. 2004;10:729-31. (6.) Cermelli C, Berti R, Soldan SS, Mayne M, D'ambrosia JM, Ludwin SK, et al. High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by laser microdissection. J Infect Dis. 2003;187:1377-87. (4.) Wainwright MS, Martin PL, Morse RP, Lacaze M, Provenzale JM, Coleman RE, et al. Human herpesvirus 6 limbic encephalitis after stem cell transplantation. Ann Neurol. 2001;50:612-9. Eric Denes * and Sylvie Ranger-Rogez * In conclusion, we think that viruses, particularly HHV-6, should be considered in ADEM, even in immunocompetent patients. In case of a positive result, antiviral treatment must be given, eventually in association with corticosteroids. We cannot recommend using corticosteroids alone because of the risk of spreading the infection. References Address for correspondence: Jose Luis Soto-Hernandez, Instituto Nacional de Neurologia Mexico, Insurgentes Sur 3877, Tlalpan CP 14269, Mexico City, Mexico; fax: 525-528-7494; email: joseluissotohernandez@ yahoo.com

References In Reply: The disease that we reported (1) was encephalomyelitis induced by a human herpesvirus 6 (HHV-6) reactivation. Our aim was to emphasize that HHV-6 can cause such a disease, even when the patient is immunocompetent, and to urge physicians to search for it. Spontaneous improvement of ADEM is regularly reported; however, when treatment is needed, especially during the acute phase, steroid therapy is frequently used. In our case, corticosteroids did not affect the evolution of the patient's neurologic symptoms. Conversely, introducing the antiherpes drags (cidofovir and ganciclovir) was followed by improved clinical signs and negative results for HHV-6 in the CSF by PCR. Corticosteroids likely influence inflammation associated with ADEM, but if ADEM is the result of a viral infection with persistent viral replication, steroids might be deleterious, allowing an increase in viral replication (8,9). (9.) Caserta MT, Hall CB, Schnabel K, McIntyre K, Long C, Costanzo M, et al. Neuroinvasion and persistence of human herpesvirus 6 in children. J Infect Dis. 1994;170:1586-9 (8.) Hudnall SD, Rady PL, Tyring SK, Fish JC. Hydrocortisone activation of human herpesvirus 8 viral DNA replication and gene expression in vitro. Transplantation. 1999;67:648-52. (2.) Mader I, Stock KW, Ettlin T, Probst A. Acute disseminated eucephalomyelitis: MR and CT features. Am J Neuroradiol. 1996;17:104-9. (5.) Schwarz S, Mohr A, Knauth M, Wildemann B, Storch-Hagenlocher B. Acute disseminated encephalomyelitis: a follow-up study of 40 adult patients. Neurology. 2001;56:1313-8. To the Editor: Denes et al. (1) reports successful treatment of human herpesvirus 6 (HHV-6) encephalomyelitis. The patient was an immuno-competent young woman whose symptoms were fever, urinary retention, blurred vision, quadriparesis, bilateral papillitis, and optic neuritis. Magnetic resonance imaging (MRI) showed multiple lesions on the spinal cord white matter and the left thalamus, and the cerebral spinal fluid (CSF) showed inflammation. The patient was treated with acyclovir for 3 days, high-dose methylprednisolone for 5 days, cidofovir for 1 day, and ganciclovir for 15 days, starting on day 23 of hospitalization. By establishing a relationship between antiviral drug doses, serial determinations of HHV-6 DNA by polymerase chain reaction (PCR) in CSF, and neurologic improvement, Denes et al. concluded that antiherpesvirus drugs led to her recovery. This case fits well in the spectrum of acute disseminated encephalomyelitis (ADEM), an inflammatory demyelinating disease of the central nervous systems of children and young adults, which occur in close temporal relationship with several infectious illnesses and immunizations (2-6). The disease has particular predilection to the optic nerves, spinal cord, brainstem, basal ganglia, and cerebral and cerebellar hemispheres. Maximal neurologic deficits are reached within several days, and resolution takes weeks or months. The condition is typically monophasic, but relapses have been reported (7). Histologic multifocal areas of inflammation and demyelinization are Ibund. In the pathogenesis of ADEM, an initial injury caused by an infectious agent, followed by a secondary autoimmune response, has been postulated, and animal models have provided experimental support; both CD4 and CD8 T cells have been implicated in a secondary autoimmune response (6). Despite the lack of controlled studies, corticosteroids are widely used to treat ADEM and high-dose methylprednisolone is the drug of choice (3,4). The largest series of ADEM in adults included 40 patients with a mean follow-up period of 38 months. The patients were given a standardized treatment regimen about herpes of methylprednisolone, 500 mg daily intravenously for 5 days, with no additional therapy if they recovered completely. In patients with persistent neurologic deficits, the initial intravenous therapy was followed by a regimen of oral methylprednisolone, which was slowly tapered over 4 to 6 weeks. In patients with no response to this therapy, or whose condition had deteriorated during therapy, cyclophosphamide was given to seven patients, and immunoglobulin was given to one patient. Thirty-eight of 40 patients improved during the acute phase of the illness; in 7, symptoms completely resolved. One patient's condition remained unchanged and one patient died; no antiviral drugs were given (5).

[lndecamp-blog-blog]

Two days ago we celebrated our first anniversary.

[alexgaskarthismydrug-blog]

[polaroidperfectphotography-blog]

[cloudyfacewithjam]

The way that lovers use is this; They bow, catch hands, with never a word, And their lips meet, and they do kiss, -- So I have heard. They queerly find some healing so, And strange attainment in the touch; There is a secret lovers know, -- I have read as much. And theirs no longer joy nor smart, Changing or ending, night or day; But mouth to mouth, and heart on heart, -- So lovers say. - The Way That Lovers Use, by Rupert Brooke