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steve0discusses · 4 years ago

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S4 Ep37: Return of O R B S

Heyyyyy boy, look who’s back, it’s orbs!

So we’ve seen a lot of orbs on this show and I fully admit that I kinda started...I started feeling a kinship for the orbs. Something about these mysterious death balls of Yugioh that we see over and over just became really relatable during a pandemic. Being trapped in a bubble and unable to get close to anyone you know is such a 2020 vibe, youknow?

These orbs that are apparently so normalized in this universe that everyone is just max chilling in an orb and just doing their best at not thinking about whether or not they’ll still have to poop in this completely transparent orb in front of all of their friends.

Also, welcome back, Yugi. Apparently he was just taking a nap this entire time. That’s canon and you know what? Good for him.

And then everyone else just kinda showed up, tired, in an orb, feeling kind of frustrated because there’s literally nothing else they can do to get out of this situation. It’s basically a zoom call in 2020.

(read more under the cut)

TBH if Pegasus was in a zoom call, you know he’d just be talking about wine. You know he’d just be in a zoom call with a bunch of straight-laced teenagers just going off about the weird wine he got from a subscription box that he bought when he was day drunk a week ago. You know he’d just be like “I mean is it good? Should I keep it? Should I drink it anyway?” While popping the cork on stream and just pouring it directly into a cereal bowl.

I can feel the orb life going on here. I can especially feel Seto Kaiba, who fell asleep during the zoom call without turning off the camera.

On the other side of the room is people dying as they get sucked directly into their impending doom.

Long ago, about...last year I think...I recapped an episode from the beginning of the season where Pegasus introduced this blank card--that I assumed was blank.

But that card from that episode--it wasn’t actually blank. It was a symbolic blank card and the show runners were like “our child audience will surely get that we just don’t want to spoil the ending” as I, a full grown adult, completely thought this card was blank.

But like...this is Pegasus. You can’t just be tossing out blank cards like that!

...anyway...it’s fine, because we get a little bit more about the time that Pegasus donned that quantum hat that is sometimes square and sometimes round and then just harassed a bunch of people in Egypt until one guy tore out his eyeball and replaced it with a Christmas ornament.

I freakin have the hardest time believing this guy was married once.

PS, now I know that when you uh put people’s hair into strips like this, it’s a lot of effort to animate and it doesn’t look anything like hair. Glad Yugioh taught me that none of us ever need to do that. Ever again. Erase that idea from your to-do list, it doesn’t work.

Anyway, Pegasus lets us know that while he was trying to revive his dead wife and putting a cold compress on his new golden eye-socket, he was also like...obsessed with finding these three dragons.

And he was like “but they didn’t exist anywhere else!” He looked in outer space?? In atoms??? all over the place (this was in the show, PS, he looked on a molecular level for these duel monster dragons) until he was like “ah! That’s because they DID never exist!”

PS...are there...molecular duel monsters?

Just asking for a friend.

...so they did exist, they just had exactly the same names they do now, but were humans so I guess Pegasus just...didn’t realize that they were the same. Kinda like how when I used to read manga as a kid or watch anime and they’d go into chibi forms I thought those were different people. It’s just like that.

Anyway if dragons are turning into humans please don’t tell that to Kaiba. Blue eyes white dragon wife is much funnier as a dragon.

But like...I get that mechanically, in the game, you have to change them to human to make the cards work but...why do we care if they’re human or dragons anyway? Dartz comes from a world where most people turned into monsters. And like if no one’s trying to date them, not even Kaiba...who cares? Dartz’ wife is a freakin monster and I don’t remember seeing him divorce her at any point.

Anyway, it was an odd thing for the show to throw in there about cards we have no relationship with. It’s a complicated season, and we spent way more time on our minibosses than we ever spent with the three tragic dragon characters that are going to actually save our asses.

Now back in the soul hut, Dartz has decided to do the strategy where he convinces Pharaoh to give up. Which youknow...

The show acts like Pharaoh has any idea of who he used to be and it’s like do you even know how long Marik spent trying to teach Pharaoh anything about his past? Like Marik stood there with his back exposed and was like “I wrote it down! See? That’s about you!! Read my back scriptures!!!” and Yami kind of squinted at it and was like “Nah...” and then the island exploded.

So anyway, the only way that Dartz can convince Pharaoh to kill himself is to show Pharaoh the invite code to the orb zoom call. And so Dartz like “your friends are having so much fun in death zoom right now, don’t you want to hang one last time? Don’t you want to see what they’re up to? Don’t you want to hear them complain about working from home and how small their orb is and how their back is cramped all the time because the park is closed so they never go on walks anymore? Don’t you want to hear and secretly enjoy how much weight Joey gained from eating Doritos for 8 straight months? Don’t you want that in your life, Pharaoh?”

And then he just...decided to possess his bean because obviously that wouldn't work.

Freakin Usagi Tsukino over here.

Speaking of:

I’m also imagining that this scene in the big ol bathtub was probably...longer...in the original version? Just saying that because...what’s the point of putting a shirt on the boy? Unless it was implied that at some point you saw the whole boy? Maybe I blinked and missed a shot of the whole boy?

Anyway this scene felt heavily edited, that’s my hypothesis, if it wasn’t and someone was like “yo put a shirt on the boy” then I...don’t know what to say about that. It’s a pair of shoulders. I’m pretty sure half of their cards are racier than that.

Do you like the evidence that we have here that Tea and Tristan totally biffed it last episode? I do.

Anyway, as the Orichalcos shrinks and threatens to take Pharaoh’s soul, the puzzle taps into his dark powers, and the power of friendship and also all the minibosses who died kinda formed a ring around him and bumped the orichalcos back into place.

Nice that Mai got added to the friend pile, but only in death. Also, I’m pretty sure Alister is here and Pharaoh never met him? But there’s more of a reason as to why the mini bosses are here, since they have their own agenda outside of Pharaoh and being his best buddy so I won’t question that too much.

This is friendship from Yami’s perspective, and like...Yami kinda wants to be friends with most people. Hell, if Bakura were introduced this season, he’d be here, too. That’s just how Pharaoh rolls.

Yami decided that, although he’s a huge mess of a human being and screw it at every possible opportunity, his core isn’t made up of a dark magic curse with a crusty soul left over from some kingdom that botched it 5000 years ago. He’s decided that he’s moving on from that sort of anxiety--becoming his own sort of person--separate from Yugi, separate from his past, and separate from the powers that he’s often defined by. And it’s about time. It’s about time he recognizes that he needs to stop clinging to the ancient past (although I’m pretty sure his ancient past will be the entirety of next season)

He should give himself a real name while he’s at it, but youknow, he's not going to. Yami hasn’t quite figured out names yet.

Nightmare foreshortening, that’s what this is. Like you have to just roll a dice when you do foreshortening, and sometimes you get snake eyes, the rest of the time, you get this.

So not only are these guys voiced by Seto, Yugi, and Joey, they have faces that are like a blend of Valon, Raphael, Mai and Alister (yes that was four people for three dragon people, just go with it)--but the show doesn’t really focus on that, or at least not in this episode.

But, it does give the three mini bosses a reason to be chosen by the Orichalcos, if it’s inferred that they were some reincarnated version of the original dragons. Especially since Valon had the ability to just punch out the Orichalcos when he was still alive, and apparently that is the same thing this card does.

I can’t believe that him punching stuff was foreshadowing. I should have known. The answer in this show is always punching.

And so the episode ends with some...something that happened, but don’t ask me about it.

One of the reasons I don’t go over card games here. I mean...c’mon.

Come the freakin on.

Anyway we have some more episodes before this is over but at least this guy is at 0 hp so like...how long can you draw out one single play of cards? (I say, knowing they can stretch this game out...infinitely)

anyway, here’s where you can read these from the top. Hope y’all are staying safe!

https://steve0discusses.tumblr.com/tagged/yugioh/chrono

#ygo #yugioh #Yu-Gi-Oh #recap #photo recap #episode recap #yugi muto #joey wheeler #maxamillion pegasus #is dead #dartz #yami muto #just a mess of orbs #S4 #s3 ep37

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wildscienceblog · 4 years ago

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My unpopular opinion about popular science topics: A new study says that SARS-CoV-2 RNA may integrate into the human genome - DON’T PANIC, this is likely not the case and even if it was, would probably lack clinical relevance :) -

For a few days now, there has been an ongoing heated discussion on Academic Twitter and other scientific outreach outlets regarding a bioRxiv preprint titled “SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome” (Zhang et al. bioRxiv, 2020). The study proposes that the sustained viral RNA shedding and recurrence of PCR positive testing after recovery might be due to retrointegration (in simple terms this is the insertion of DNA sequences into a host genome mediated by an RNA intermediate, the enzymes reverse-transcriptase and endonuclease and chaperone proteins) of SARS-CoV-2 into the DNA of patients (i.e. their nuclear DNA). The senior author is the renowned scientist Rudolf Jaenisch who together with Beatrice Mintz, produced the first-ever transgenic mammals by injecting retroviral DNA into early mice embryos. He is a professor of biology at MIT and his lab based in the Whitehead Institute for Biomedical Research works on epigenetics and epigenome editing and transgenic models to understand neurological disorders and cancer and has recently included research on SARS-CoV-2. This research focus is shared by his co-authors, who also are postdoctoral researchers at his lab. The first author, Liguo Zhang studies epigenetics and nuclear organization in the nervous system and how their misregulation leads to diseases, followed by Alexsia Richards who is currently examining the tropism and transcriptional response to SARS-CoV-2, Andrew Khalil focuses on understanding the role of the adaptive immune system in regulating metabolism, Emile Wogram combines stem cell technologies, genome engineering, biochemistry, and proteomics to study microglial phagocytosis, and Haiting Ma is concerned with studying signaling pathways and epigenetics of stems cells differentiation and maturation into functional lineages. Richard A. Young also a professor of biology at MIT and a member of the Whitehouse Institute pioneer in the systems biology of gene control in health and disease also participated in this research.

Nevertheless, these findings are raising many eyebrows among the scientific community, especially under the current climate where an mRNA-based vaccine against SARS-CoV-2 is already approved in some countries and another one to be soon authorized (see here and here if you want to learn more of the current status on vaccines’ roll out). Scientists from fields ranging from immunology to cancer biology to the closest it gets to the topics being addressed in the polemic study, mobile elements, transposons, and endogenous viruses as well as clinical virology, have sharply criticized the soundness of their conclusions and are calling for the retraction of the preprint.

A major concern is the adequacy of the experimental assays used to support the hypothesis of retrotransposition events. Zhang et al. (bioRxiv, 2020) report to have found chimeric transcripts of fused viral and cellular sequences in published data of cultured cells and primary cells of patients. They overexpressed human LINE-1 or HIV-1 reverse transcriptase in cells which were then infected with SARS-CoV-2 and applied a single-molecule RNA-FISH (i.e. an in situ hybridization method that uses probes of multiple oligonucleotides to detect individual RNA molecules inside of single cells https://sites.google.com/site/singlemoleculernafish/home?authuser=0) to confirm that viral sequences were integrated and detected their transcription in the nucleus of the cells overexpressing LINE-1. They also analyzed published data on LINE-1 expression in cells infected with SARS-CoV-2 and chimeric read abundance and found a correlation between these two. Furthermore, they suggest a molecular mechanism by which LINE-1 expression can be stimulated under SARS-CoV-2 infection via cytokines. However, Cedric Feschotte a professor at the Department of Molecular Biology and Genetics in Cornell University with 20 years of experience studying mobile elements points out that these experimental approaches are insufficient to sustain an in vivo retrotransposition because they omit gold standard techniques such as isolating and reporting of “the sequence of the integrants along with flanking genomic regions (junction sequences spanning both viral and flanking DNA)” and fail to present hallmarks of the proposed LINE-1 dependent process (e.g. short direct repeats flanking integrant, integration at preferred L1 endonuclease cleavage site [TTTT/AA], polyA tail at the 3’ end or chimera with the 3’ end of endogenous L1/Alu). A generalized opinion among critics of Zhang et al. (bioRxiv, 2020) is that the chimeric reads are likely to be artifacts of library preparation or template-switching events and that their approach does not rule out these possibilities.

Aris Katzourakis, a professor of Evolution and Genomics at the University of Oxford whose research is centered in the study of ancient viruses and uses endogenous viral elements, including retroviruses tweeted: “ … genomic integration of coronaviral DNA is highly implausible, given there is not a single known genomic fossil of integrated coronaviruses in any know host genome that has ever been sequenced to date.” Which is a strong and educated argument (yet not a smoking gun) against the evidence presented by Zhang et al. (bioRxiv, 2020). Moreover, various academics argue that even if substantiated under experimental conditions, is a whole different thing to prove retrotransposition happening during natural infection with SARS-CoV-2. Clinical scientists draw attention that is definitely not unique to SARS-CoV-2 the persistency of viral debris in tissues of convalescent or recovered patients (even though its mechanism and clinical relevance remain subject to discussion e.g. see here). Altogether, they agree that its clinical relevance is far from proven and unlikely to exist.

As dull as it is for me, I am merely a spectator here since, despite my keen curiosity for genetic mobile elements, I have very limited first-hand experience on these subjects. I do think that a take-home message is that probably many features described as novel or unique to SARS-CoV-2 (which sometimes alarm scientists and the general public alike) might be in fact more ubiquitous than the flood of SARS-CoV-2 scientific papers would have us believe. In my opinion, the reason being that the acuteness and the timing in terms of technology and communications of this pandemic have powered studies at scales that have not been possible to conduct in other disease outbreaks. In other words, we are looking too much, too close, and perhaps missing a bigger picture (I have seen a strikingly low number of papers building upon previous knowledge on other coronaviruses, especially at the clinical level). Whether or not SARS-CoV-2 integrates into our genomes and if so, whether this has clinical implications, is definitely something that cannot yet and should not be answered based on the findings by Zhang et al. (bioRxiv, 2020). It is also safe to say, that whereas the semantics can be confusing for the general public, even if retrotransposition is later proven to occur in vivo during natural infections, there is still a long shot from there to assert that this implies a direct risk for mRNA vaccines to integrate into our genomes because they are designed such that they do not interact with our DNA (they do not go inside the nucleus, you can read more about the different vaccines and their mechanisms here). Having said that, clinical usage of mRNA vaccines is new, and we will be confirming and learning more about how they (hopefully well!) work soon.

Lastly, I want to share that my motivation to write this piece was not so much the hot topic that SARS-CoV-2 is but rather the atmosphere that this paper as others in various fields which present (seemingly) premature conclusions and bold takes have triggered. This paper has the feature of being presented as a preprint. Preprints have the goal of allowing the scientific audience “to see, discuss, and comment on the findings immediately” before peer-review is completed. Therefore, while I find most critiques to this paper very compelling and I strongly agree that when a bias or unsubstantiated evidence is identified, this should be acknowledged and corrected, I consider a poor scientific practice to demand a retraction of a publication at a stage that has precisely the aim of calling for discussion. I am talking now of a number of papers I have seen being targeted by similar reactions. The intentions of authors cannot be, of course, inferred, so why not waiting for them to take part in the discussion before deploying what seems like attempts to bowdlerize rather than enriching, correcting, or helping improve. Has not this been the case of most wondrous and prodigious scientific findings and technological advances? In the past, findings that were about to change the world but too odd for their surrounding context (please let me be clear that I am not referring to any particular paper that I believe to have such potential, but rather to a general attitude towards outliers of the mainstream) were met by generalized disbelief and mockery. I thought that we have already moved away from the practices that discourage sharing surprising results. Of course, there is a thin line between sharing to prompt healthy discussions and incurring unethical practices, but where are going to end up if we try to ban everything that does not comply with our preconceptions? And even if claims end up being wrong, how are we supposed to ensure that they are corrected if we promote distrust and an unwelcoming arena. Is this a retrogression powered by a more than ever intolerant society? or it never left and is it just becoming evident as communications allow it? I think we should do better.

#covidー19 #sars-cov-2 #rna #retrotransposons #dna #science #epigenetics

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raspberryjones · 5 years ago

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At This Time...

Sitting here paralyzed for days, trying to figure out what more I can do. Quarantined, distracted from grading these final papers by the fires in my feed, knowing that donating to activist organizations and RT’ing, on top of crying, shaking and cursing, is not nearly enough. Plus, just about anything I say/do on the socials feels like a f*cking performance. All of it — except the anger and the stream of information that continues to reassert the utter disdain that this country’s White supremacy (not just Tr*mp, but the whole friggin’ establishment) has for Black and Brown people, here and throughout the world. The insidiousness.

Even wallowing in my own exhaustion — jobless, hope on a tattered string, watching the powers that be f*ck the populace over in every way imaginable… All of it feels self-pitying, when I can recognize my privilege and be struck by the existential sorrow that, even before this week’s events, or the racial disparity of the pandemic’s victims, surrounds most Black American lives. When I hear my Black and Brown friends and colleagues express their own exhaustion, as so many have over the past five days, it has the weight not just of the moment, or a political term, but of history. Personal, familial, written in volumes, reaffirmed constantly — and running contrary to America’s dip-shit self-mythologizing.

And yet... Despite this horror-show past, with white supremacy’s attempts to subjugate them for generations, Black America’s ability to move society forward has been beyond fucking remarkable. The creation of culture, the strength of moral character, the depth of communal compassion. It is no overstatement that the moral and creative compass of not just Black excellence but of the African-American community I’ve known, has been among primary lodestars of my life in this country. And while I do not expect all other folks to feel the same way I do, I most certainly judge those who feel contrary — or those who dismiss the notion that, if anyone’s ever made this hard land great in the past, it’s been Black Americans.

And that in the struggle to understand the fullness of this account, you will find pretty much all contemporary crises. It’s incredible that, in 2020, a majority of people still don’t comprehend the connections between systemic white privilege and Black death in the headlines, between colonization culture and the overwhelming inequality rampant in American society, between the contemporary malaise of the Western imagination and the whitewashing of the media. For a person who does not simply work in/with culture founded on the Black experience, but gets their very lifeblood form it, this is a hard fucking pill to swallow. The big “YOU don’t get it!”

So, when thinking about WTF else I can do, as a writer who deeply supports Black American communities in the struggle against white supremacy, I thought it worthwhile to reiterate some of this historical record’s personal and social importance. Having just spent a semester teaching NYU sophomores about how we got here — while re-reading classic texts by LeRoi Jones and Ralph Ellison and Isabel Wilkerson, Nikole Hannah Jones’s massive new one, and discussing the contemporary settings of these ideas with DeForrest Brown Jr. and Angel Bat Dawid — what I believe should be our collective mission is fresh and clear in my mind.

This is where music comes in. It’s especially important that anyone who listens to contemporary music in the 21st century, also participates in reappraising these whitewashed texts, restoring Blackness back to the center of this culture. Not only to acknowledge the proper origins of the forms and ideas that are so important to it — and thus, acknowledge the people who developed these forms and ideas — but act accordingly in times of crisis, requiring us to use our white privilege to support pro-Black and anti-colonialist positions in a way that could actually lead to structural change. To “see something, say something” when companies belligerently monetize the (Black) people’s culture and do not recompense the community, or when cops act like overseers that treat Black lives as wanton boys do flies.

Because… Here’s the thing: blues and jazz are the basis of all great new music of the last 100 years — paving the way for the post-modern Black electronic music (hip-hop, house and techno and electro) which is the core of pretty much all popular sounds of the 21st century. And the Black experience is the DNA of these musics — meaning, in the clearest terms, that we don’t get to have this music without the burden that preceded it. This is at the core of the accusation that “loving Black culture more than Black people.” You do NOT get to do one without the other, and still call it “love.”

Unlike European art, that original Black music is not the product of some art-school- and conservatory-learned experiments. Or of commissions from a royal court. Or of direct updates on thousand-year folk forms. Oral traditional and molecular memory aside, Black American music’s past was almost completely — genocidally, is also a word — wiped away in the Middle Passage. So when it came to fruition in the years during and after Reconstruction, it did so as a personal Black expression of what to do and how to live in this new, foreign here-and-now, far from “home.” This music is, simultaneously, a lament and celebration, complaint and utopia, art and evidence, personal diary and modernist work. Nothing like that had been conceived before, and it was so revolutionary that almost no one’s been able to build a next-level to it since.

It was also the first musical art-form original to the United States. Now imagine: the engine of this art-form’s motivation was a desire to express oneself within a society that did not want to hear any of what you had to say. A society that, in many cases, did not regard you as fully human. And yet think of how Black music expresses the full spectrum of humane truths and emotions. Actually, fuck it, don’t read me telling you about it. Go listen to the Wesley Morris episode of the 1619 Project podcast, who does a far better job than I of narrating Black American music’s wonders. This is why remaining on the sidelines, or providing only cursory support to the uprising, does not sit well.

It is crucial that people around the world know this history when they hear a variation of these musics being described as “global phenomena” or “universal,” or divided into “genres.” Such terms might seem neutral, or even complementary to its creators; but at their core, they move to dilute the role that the Black experience played in its birth. And distancing the music from the people who made it (and why), mitigates the music’s values. What was once specific becomes conditional — out goes the particularity of its expressions (feelings, words, citations), and in come market-democratizing generalities, like capitalization and trends, elements that tend to be elevated by whoever controls mass communication. This is how a local culture becomes a global genre, and how some people who make “techno” or “jazz” music in [insert European city here] can’t comprehend why “neutrality” towards George Floyd’s death is a betrayal of their creative work.

But... They will do as they will do. And, as I said before, we will judge them - because it is on these very decisions and proclamations that the intention of the art-work (a crucial aspect in the value of the art-work — its contemporary “aura” some might say), that artists and their audiences are judged. And when I mis-step, my Black friends and colleagues will also judge me, and the humility and self-reflection with which I handle this will say volumes about what my cultural intentions are. Because for the rest of us, there never has been nor will continue to be a disconnection between the culture we have sworn allegiance to, and the need to change society’s norms, to speak about the need for social justice, and to continually reassert that #BlackLivesMatter and #BrownLivesMatter.

And that if you continue to engage with the words and ideas that I hope to continue putting out into the world, this is their starting point. That music — for all its glory and hope and joy and wrenching feeling and fuck-you energy and let’s-love energy and all that — is neither the beginning nor the end. It is one narrative of history’s arc. That chapters of this history are being written all the time, some quietly and some in push-notifications, and that what’s going on outside our windows at this moment, is a major scene of the permanent record. To be quiet is to be complicit. I choose not to be complicit. I hope that you make that choice as well.

youtube

#blacklivesmatter #brown lives matter #how to be an ally #jazz #techno #House Music #black music #hip-hop #sister rosetta tharpe

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bme-girl · 4 years ago

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University asks

from this blog

How far along are you in your studies? About to start the 4th/5th year of my undergrad program. So close, yet so far lol

How far do you plan on pursuing academia? I want to get my PhD and maybe I’ll do some post-doc work after that?

What made you want to attend university? My mom wasn’t able to attend in her home country and my dad got his Bachelor’s on his dad’s GI Bill. They allowed me to see how there are some limits without it and how education in this country is your ticket to money and living comfortably.

What do you study? Biomedical Engineering + Chemical/Biological Engineering

What do you wish to accomplish by studying at university? The end goal is to contribute to the knowledge in the field and have an impact on the community by inspiring underrepresented youth like me

What do you want to do with your degree? Be a researcher and teach in some capacity

What’s your dream job? Being a researcher and influencer for Latinx youth in STEM

Has university been what you expected it to be? Tbh, I don’t think so even though I didn’t really know what to expect. I’ve learned SO much along the way that no one had the knowledge to tell me when before uni

What’s the most important thing you have learned about yourself at university? That I’m strong af, I can do whatever I want to in life–literally. And not to compare yourself to others

What surprised you the most about university? The types of friends I made, people I met, and places I went bc of opportunities through uni

What classes are you taking this/next semester? For fall 2020, I am taking Chemical Engineering Design 1 (not truly a design class. more like ethics, safety, etc.), Transport Phenomena in Biomedical Eng, Separation Processes, Biochemistry, and an Independent Study.

What has been the most interesting class you’ve taken? This past semester I took a biomedical eng project-based course and it was LIT af, very challenging but projects were super realistic and interesting

What has been your favourite class you’ve taken? Same course as 12^ like it made me realize my true style of learning and working and it was difficult but so so cool

What is your favourite professor like? Haha, same prof as 12 & 13^^ he was laid back, challenging, young and tech-savvy. More than anything, he was there if you just needed someone to talk to. He didn’t ‘bend’ rules but he knew what it’s like to be a student with limited resources and no super-human abilities. Just a cool guy I’d grab a drink with

If you have to write a thesis, what are you going to write it on? I will have to provide a written report for the independent study so I’m gonna ask if it can be like a thesis. It’ll probs be on something like improving multi-modal neuroimaging data fusion using machine learning

What is your weird academic niche? I’m not really sure. Sometimes I feel like I am my own niche? Lmao. I don’t really know how to answer this tbh

What’s your favourite thing about academia? That honesty and integrity are highly valued and people just like wondering about things on a deeper level and bigger scale and have conversations about it

What’s your least favourite thing about academia? That it’s toxic: not as diverse, kinda bureaucratic, research matters more than ability to teach (in the US)

Would you go to a different university if you had to choose again? Yes and no: instead of going to a different uni then transferring to where I am now, I would 100% just have gone to the one I’m at now in the first place

Would you choose a different subject if you had to choose again? I don’t think so

If you couldn’t study the subject you study now, what would you study? Software Engineering or Comp Sci

What is your favourite course style? More applied learning, like projects. Not as exam heavy.

Theoretical or practical? AHHH! Both

Best book you’ve had to read for a course? Numerical Methods in MATLAB for Engineers

Worst book you’ve had to read for a course? Molecular Physical Chemistry for Engineers by Yates and Johnson OMFG LITERAL TRASH, even our instructor hated it

Favourite online resource? YouTube lol– broad but legit the best way to learn ANYTHING

The topic of the best essay you’ve written? I have a problem where everything I wrote in the past I now see as really bad bc my writing is always evolving. Most recent essay–maternal mortality rates in the US and race gaps within

Would you ever consider getting a phd? I am indeed considering haha

Who is doing the most interesting research in your field at the moment? In my research, Vince Calhoun or Danilo Bzdok. In my major, I’m not sure

Do you have any minors? I haven’t declared it officially, but I think I can achieve a math minor my 5th year

What is subject you wish your university taught but doesn’t? I don’t blame them cause it’s just now gaining more popularity, but like a strictly computational biology/biostatistics subject would be amazing

What is an area of your subject you wish your university taught but doesn’t? Same as 31^

The best advice anyone has ever given you about university? Do everything, don’t hold back. An opportunity can come from the smallest of things

Do you care about your grades? Yeah, but it’s not everything

Do you think you study enough? Sometimes I do, sometimes I don’t

How did your attitude towards studying and school change between high school and university? Uni hit me like a truck bc my high school was not the best. I learned to live and breathe studying, how to learn, how to manage my time, and my attitude is more serious and business-minded, but also have crazy fun in the right time and place

What do you do to rewind? Like to unwind? exercise, make music, watch movies, hit the hot tub

Best tip for making friends at university? Be yourself and be honest :)

Are you involved in any clubs/societies/extracurriculars? President for a diversity student org and I do intramural sports!

Have you done or are you planning on doing any internships? I’ve completed one research internship and I hope to do another next summer.

What is an interesting subject that you would never study yourself? Physics probably lol

What has been your favourite thing about university so far? The people, the location of my uni, the learning

What is your plan B career? Work in industry after undergrad, probably in biotech

Do you ever regret your choice of subject or university? Not really

Do you ever regret going to university? Hell no

How do you study? I try to vary it– I’ll read, do a crap ton of practice problems, do a study group with a lot of talking and teaching each other concepts, watch videos from other sources

What do you wish you’d done differently in your first year? Not been a student-athlete

What things do you think you did right in your first year? Was honest with myself

What are your thoughts on Academia? It can be good and bad, and it’s up to us as the next generation to change the bad :)

Strangest university tip you have? Hmmmmm... Don’t assume all your advisers/administration/profs know what you’re truly capable of. (not strange, but I don’t think it’s that common)

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subboxy · 5 years ago

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LookFantastic Beauty Box March 2020 Review "Unconstricted" Edition + 15% Off Coupon

It's time to review the March 2020 LookFantastic Beauty Box! LookFantastic is one of my favorite beauty subscription boxes! LookFantastic sends you 6 luxury beauty products (with guaranteed value of over $60), a copy of ELLE magazine, and a Beauty Box magazine filled with tips and tricks to help you look your best. You'll get a mix of a mix of cosmetics, hair care, skincare, body care and beauty tools in both deluxe sample and full size products! Price: $19/month Shipping: Free DEAL: Get 15% off your first box using this link and coupon code BLOOM15. We were sent this box for review purposes. LookFantastic Beauty Box March 2020 Review "Unconstricted" The March 2020 LookFantastic box shipped in a pink box with a beautiful design of women from around the world. Don't you just love this design?!?

The theme of this month's box is "Unconstricted". This month's focus in collaboration and inclusion. In March, we celebrated International Women's Day, so this box theme made a lot of sense!

Each month, LookFantastic includes a booklet that has all the deets of what's included in the box and other beauty and lifestyle tips!

The inside of this month's box has a quote that says "In a world where you can be anything, be yourself". I wish I had this quote and learned this when I was a teenager!

LookFantastic always wraps their monthly beauty goodies in colored tissue paper. It's like getting a monthly gift for yourself!

Here's our first peek at everything we got in our box!

Madara Organic Skincare Time Miracle Wrinkle Resist Eye Cream - Worth $44.64

I was super excited to see this eye cream! One of the first areas on your face to get wrinkles (for me anyway) was near my eyelid area. This eye cream targets signs of tiredness and aging, as well as tackling fine lines and wrinkles. It will intensely hydrate and Target science of fatigue, crow's feet, and Fine Lines, weaving your eye Contour skin comforted and more resilient. It has multi-molecular hyaluronic acid, physio-moisturizers and antioxidant-rich cellular bio complex, to deliver profound care and strengthen your defense against daily stressors. You can use this eye cream in the morning and at night around your eye area. This cream has been dermatologist tested. 97% of people report they have better looking eye contour skin. 88% of people say they have less visible lines and wrinkles. Sign me up!!! Grow Gorgeous Intelligent Haircare - Worth $4.78

You can get visibly thicker and more nourished hair with this unique hair mask from Grow Gorgeous. It is formulated with caffeine to stimulate your roots, oat lipids to lock in moisture and hyaluronic acid for a silky soft finish. You can apply this to clean damp hair by massaging The mask into your scalp and smoothing it through the length of your hair. All you need to do is leave it in for 10 minutes and then rinse thoroughly. Rituals The Ritual of Ayurveda Nurturing Shower Oil - Worth $6.25

This shower oil has a lovely scent! The base of the shower oil is Indian Rose and Sweet Almond Oil, which leaves your skin feeling soft and will put your mind at ease. To use this oil, you pour a few drops into your palm and massage it all over your body in circular motions. Upon contact with water the soil changes into a luxurious foam, leaving you feeling clean, refreshed, and smelling delicious! Rodial Bee Venom Cleansing Balm - Worth $16.58

You can take your facial cleansing routine to the next level with this luxury skin brightening cleansing balm from Rodial. It is formulated with bee venom, which is an anti-aging wonder ingredient that wmooths your complexion, pumps fine lines, and decongests your skin of any dirt and impurities. To use the cleansing balm, you should massage a queen-size amount onto your dry face. Then splash a small amount of water on your face to emulsify and allow the balm to transform into a milky cleanser. Then rinse it off. bellapierre Kiss Proof Lip Creme - Worth $10

I think we got a bonus in this month's box, because the lip creme from bellapierre is not listed in the booklet. This perfectly pink lip creme provides full coverage and last for hours without needing a touch up. The creamy formula goes on smoothly and dries to a beautiful matte finish in a snap! Elizabeth Arden Superstart Skin Renewal Booster - Worth $9.57

The skin booster from Elizabeth Arden is designed to restore your Skin's natural ability repair and renew. It has a fusion of super ingredients that has resulted in over 90% of women agreeing that it helped their skin look less damaged and irritated. To use this booster you apply one pump on to your freshly cleansed face, before applying serum and moisturizer. Hairburst Chewable Hair Vitamins - Worth $15.93

I can always use a little help making my hair look healthier and shinier. These hair care vitamins from Hairburst will help you combat effects of heat styling, coloring, and aging. Research shows that 98% of users and noticed faster hair growth taking these vitamins. For best results,. you should take two capsules per day ideally both together in the morning before eating. In Summary

I am in love with all of the wonderful beauty products that LookFantastic curated this month. They will definitely help make me look and feel my best. My favorite item in this month's box, hands down, is the Madara Time Miracle Wrinkle Resist Eye Cream. But I do love all of the other skincare, beauty, and hair care items as well! Retail Value: The retail value of the February box was a whopping $107.75 USD, which is a really great deal for only $19! DEAL: Get 15% off your first box using this link and coupon Check out our past LookFantastic Beauty Box Reviews! Join Read the full article

#beauty #beautybox #lfbeautybox #lookfantastic #lookfantasticbeautybox #lookfantasticreviews #monthlysubscription #subscriptionbox

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goldeneyedgirl · 5 years ago

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2019 Fic Meme

My end of year fic meme, compiled from some old Livejournal fic memes that I do when I write stuff. I do this for fun, because I like looking back at what I have and haven’t written, and what keeps popping up again.

It’s meant to be silly fun, and if anyone else wants to do it, PLEASE DO. I don’t want to tag anyone and put pressure on you in case you don’t want to/don’t think you have enough fic/hate memes.

Twilight

12 Days of Fic-Mas (Twilight, WIP) Day 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, bonus. Twelve days of fic extracts, previews, and drabbles focusing on Alice Cullen. Encompasses Folie A Deux, The Only Girl in the World, JessaminexAlice, Omens, Asylum, The Long Way Around, The Dark and the Unknown, Hybrid, Runaway, All These Broken Things, & The Unexpected Second Life of Mary Alice Brandon

Shadow to Light (WIP) (Alice/Jasper, AU Angst, PG) In 1918, Jasper lures the newborn known as Mary-Alice back to Monterrey. He is lost to her before it even begins.

Total number of completed stories: Lol.

Total word count: 33,304 words were posted.

Looking back, did you write more fic than you thought you would this year, less, or about what you’d predicted? Look, I just... 2019 was a wash in so many ways. I played a lot of Fortnite really badly. I would have loved to be able to say Shadow to Light was finished, or that I was posting Hybrid regularly or something, but I can’t. I wish, wish, wish I had posted more but alas.

What pairing/genre/fandom did you write that you would never have predicted in January? Outside of Twilight, I dabbled with some reader/Ben in the Umbrella Academy, and I was messing around with some Janet/Wanda in my personal MCU canon. As for Twilight, I think my stuff got a lot darker? Like, we’re down the rabbit hole here, and somehow Alice ended up being the most feared vampire in the Americas? Yeah.

And there’s the Avengers/Twilight fic that is simultaneously three fics and one fic because I cannot make Executive Decisions and I can’t decide if I like 1. Alice knowing Bucky from Before Jasper; 2. Alice knowing Hawkeye from when he was a kid in the circus and being how Natasha and Clint got out of Budapest, or 3. the Volturi hooking up with Hydra and ... yeah, I think this one is legit the most second-most one of the most embarrassing things I’ve ever written. (I’ve been filing today, and boy howdy have I written some actual shit.)

What’s your own favourite story of the year? Not the most popular, but the one that makes you happiest? That’s like making me pick a favourite child. I’m always so, so proud of Shadow to Light, and I love The Dark and the Unknown ‘verse, and Hybrid is just hanging out there, chilling and ugh. My babies <3

Did you take any writing risks this year? What did you learn from them? TwilightFicMas was a huge risk! I wasn’t sure anyone cared unless I was posting more Shadow to Light, and people were SO nice and enthusiastic. So I guess the lesson is shut up and share more fic? Get out of your own head and spend time in the community because fandom isn’t meant to be lonely?

Do you have any fanfic or profic goals for the New Year? I’m starting a graphic design business AND my masters in design in 2020, so I figure fic is going to be my downtime next year. Ideally, I would love to get STL finished, Memento Vivere’s sequel going, and have a few of my shorter pieces posted. I would really love to get some of my original stuff ready for publication, but I’d be happy studying, running my business, and doing the fic thing for 2020.

My best story of this year: That’s up to the readers, I guess. Everyone seemed obscenely enthusiastic about The Unexpected Second Life of Mary Alice Brandon, though, and I was not expecting that at all - I was actually upset that I left the ‘dud’ fic for the last day of FicMas.

My most popular story: Shadow to Light. Everyone is so nice and enthusiastic and polite about that one. I’m not used to it! Fandom for me is usually me sitting in a corner, doin’ my obscure thing, and maybe one or two people will read what I’m working on.

Story of mine most under-appreciated by the universe, in my opinion: I think everyone was super enthusiastic and nice about everything I posted this year. Maybe Folie A Deux? But like, that reflects more on me and the excerpts that I chose to post rather than the fic or the audience itself.

Most fun story to write: The Unexpected Second Life of Mary Alice Brandon because that Alice is so happy; I have this playlist for it that is super upbeat and funky.

Hybrid is fun because that Alice likes to torment Jasper. He understands Edward on a molecular level once Alice arrives.

Most Sexy Story: The Dark and the Unknown is the front-runner for that, because most of the sexy goings-on in Shadow to Light is very much focused on the psychological and emotional aspects rather than the physical.

Story with the single sexiest moment: The Dark and the Unknown. I am still deeply uncomfortable writing sex scenes, so this may be the only one I ever do. The implication of a blow job in Shadow to Light nearly kill me tbh.

The forest behind the school is silent; just her breathing, and the slight wind. No birds or wildlife, none of the hum of the traffic or of the school.

They don’t undress more than necessary, her skirt slid to her hips, and he takes her roughly against a tree, flakes of bark falling into the dirt. She is hot and slick, and silent as he fucks her, his fingers digging into her hips, a growl rising in his chest. She is every bit his fantasy; the smell of damp flowers, the sweetness of her flesh, her willing supplication. His fingers tear through the lace of her tights as he grips her thighs, and the heels of her shoes must be bending, she’s digging them into the backs of his legs so hard.

Most “holy crap, that’s wrong, even for you” story: The Long Way Around makes Jasper and Alice’s relationship pretty fucked up, and tbh I look back at it and really struggle with how dark it is and how dark Jasper’s character becomes. There’s a reason that Shadow to Light is the ‘official’ version - it’s a better balance, and I actually think Maria is a lot more interesting in Shadow to Light as a villain with complex relationships with both Jasper and Alice to the point where none of them really want to have to kill each other, but there is a lot of hate on both sides.

Story that shifted my own perceptions of the characters: That’s a hard question. Shadow to Light definitely did that because I had to consider what happened when you took Alice out of the picture, and how that changed what happened, and considered the inter-family relationships. So much of canon relies on Alice’s visions that things can’t just happen the same way.

Hardest story to write: Shadow to Light isn’t easy because I have such a specific idea of how it plays out, how it ‘looks’ in my head, and because Alice is so fundamentally different to canon. More innocent when it comes to normal interactions, and so controlled because it meant life or death - but she’s still got to be Alice in a way that people can recognize. It also has to sound right? If I can’t get the right turn of phrase for one scene, it has to be put aside until I can work it out.

All These Broken Things is hard because I started it back in, like, 2014ish and my writing and understanding of the characters and canon has changed so much - plus there are a few sections that came to me quite early in the writing, and now sound really out of place, but are such a strong linchpin for the story that I have to rework them in. It’s a good kind of hard, though, because I’ve improved so much, my ideas and goals are more refined.

Most disappointing: Omens is a little bitch, honestly. I started it for a fic contest and kept going to explore Alice’s human life, and it doesn’t quite feel like my writing? It needs reworking, and be a little less obvious because I think the ‘four horsemen of the apocalypse’ is a good theme for a Human!Alice fic.

Easiest story to write: Depends on my mood; Hybrid is great when I’m in kind of a ‘girls kicking ass’ mood and boot up my action girls playlist.

Biggest surprise: Hybrid started as a love story that was basically ‘yeah, let’s make this shit super dramatic and overwrought’, and turned into this actual story with a huge focus on family and relationships. I can’t remember why I decided Alice’s father had a husband except that I was thinking about small town ‘otherness’, and LGBT+ people can and are still considered ‘other’ in these spaces.

Then you add in Alice and Cynthia who are basically in the same boat but have been separated for their entire lives. Alice has knowledge in her corner, whilst having to fight through foster care, abuse, and hospital; whilst Cynthia has lived a very normal but privileged life as the daughter of a mixed-race same-sex couple in a very small town. I went full-hog with this, and added in an extended family, because I really hated how canon went balls-to-the-wall to isolate Bella from everyone, including Charlie.

Like, this thing is a monster, and whilst I plan to sit down and rewrite the outline (which dates back to 2016, and I hate the ending of), I stopped outlining at 65 freaking chapters.

Most unintentionally telling story: I think this question that still confuses me finally gets a decent answer in The Dark and the Unknown - Jasper is seeing most of it from his perspective, and there isn’t a ton of dialogue. I’ve tried to avoid an info-dump, but it’s meant to be quite supernatural in tone, and focusing on vampire senses and gifts enhances that.

Story I’d like to revise: All These Broken Things wins that one. Due to the age of the piece, there are some pacing and tone issues in later chapters that are the reason I haven’t formally posted it.

Story I didn’t write but will at some point, I swear: Oh man, I really want to finish A Thousand Years of Solitude, which is a Tanya fic. I’m really happy with what I’ve got so far, but it sounds smarter and more layered than it really is, so I’m kind of stuck.

Mad World because Romani!Alice is super sassy and taking 0% of Swan or Cullen bullshit - I think 90% of my fic is just me going, “yeah, that’s not how normal people react.” And I’m a sucker for gothic horror.

What else? Aww, Against A Wall which is AU Human Jasper coming from the shittiest home, and Alice finding him. It’s meant to be short, and another one I have a really clear idea of how it needs to work.

And the one where Alice’s gift is a sentient power that pushes her to follow it; that Bad Things happen if she doesn’t; that Renesmee was always Endgame for Something, and Alice was a key piece to get that result. Or the one where Aro takes Alice as a ‘guest’ for a period because of Edward and Bella, and Alice’s gift is basically broken.

Good times. I have like 5 years of fic on this computer, we could be here for awhile.

#my fic #twilight fic #meme #my writing

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aaltohelsinki · 4 years ago

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Meet the 2021 team!

Hello everyone! The Aalto-Helsinki 2021 team has already been working on our project for a few months at least but we haven’t fully introduced ourselves here on the blog. Nevertheless, we have already introduced ourselves on our Instagram page (go give us a follow if you haven’t already 😉). Our team consists of 10 highly motivated students from the two top Finnish universities, Aalto University and the University of Helsinki. We all have very different backgrounds but what we have in common is that we all want to create future innovations to global challenges.

Sally, Team Leader

I’m currently studying in the Microbiology and Microbial Biotechnology Master's program at the University of Helsinki. I am originally from Northern California in the USA. I attended the University of California, Davis (UC Davis) and graduated in June 2020 with a Bachelor's Degree in Global Disease Biology with a minor in Public Health Sciences. I am interested in medical microbiology and healthcare-related biotechnology, specifically the use of viruses in gene therapy, but I don't have any lab experience with this. I would say my true passion is education, and I hope to improve communication between scientists and public health workers.

In this year’s iGEM team I’ll be working in the wet lab and I’m also a part of the fundraising team and blog team.

What comes to my hobbies, I love to hike, play volleyball, write short stories, cook new recipes, and I'm currently learning how to play the drums. Also, my favorite ice cream flavor is chocolate chip cookie dough.

Emma, Team Vice Leader

Originally, I come from Oulu and I moved to Helsinki to study Energy and Environmental Engineering at Aalto University. After my first year, I chose bioinformatics as my minor and felt really excited about courses more related to biosciences. This led me eventually to change my study direction and apply for the Biology Bachelor’s program at the University of Helsinki. The coolest thing I’ve ever learned is evolution as a whole - knowing where we come from, the origin of life, and the events that lead us to this moment!

In this year’s iGEM team I’ll be mainly working in the dry lab but also the wet lab. I’m also a part of the fundraising team and I’m responsible for our website.

My hobbies include hiking, cooking, reading, knitting, music. Also, my favorite ice cream flavor is coconut and salted caramel.

Anni

I’m currently studying in the Master’s program of Genetics and Molecular Biosciences at the University of Helsinki and I’m starting in the Life Science Technologies Master’s program at Aalto in the Fall. I am originally from Porvoo, Finland, and now living in Helsinki. My areas of interest are genetics and bioinformatics, and in the future, I would like to work with innovations to promote medical and health technologies.

In this year’s iGEM team I’ll be mainly working in the wet lab but also in the dry lab. I’m also a part of the social media team and blog team.

My hobbies include playing the guitar, painting, running, and doing other sports. I love to spend time outdoors and in nature. Also, my favorite ice cream flavor is chocolate.

Anniina

I’m currently studying Biosystems and Biomaterials Engineering at Aalto University and I did my Bachelor’s in Bioinformation Technology at Aalto University. I have always thought that biology is complex and I wanted to learn how biological systems function on a molecular level. I think biophysical chemistry and programming have helped me to understand biology more in-depth.

In this year’s iGEM team I’ll be working in the dry lab and I’m also a part of the fundraising team.

What comes to my hobbies, I really enjoy cooking and baking! I also like to spend my time swimming, cycling, thrifting, and learning how to use oil pastels and paints. Also, my favorite ice cream flavor is hazelnut.

Enrique

I’m currently studying in the Master’s program in Microbiology and Microbial Biotechnology at the University of Helsinki. I am from Madrid, Spain. I did my Bachelor’s in Biotechnology at Universidad Politécnica de Madrid. My areas of interest are biotechnology, music, history, and art history.

In this year’s iGEM team I’ll be working mainly in the wet lab but also the dry lab. I’m a part of the fundraising team and the blog team as well.

My hobbies include playing the guitar, football, and theatre. Also, my favorite ice cream flavor is chocolate.

Iiris

I’m a student of the Molecular Biosciences Bachelor’s program at the University of Helsinki and I have computer science as my minor. I’m really interested in molecular biology but also computer science, technology, and innovations and I would like to combine these in my future career.

In this year’s iGEM team I’ll be mainly working in the dry lab but also in the wet lab. I’m also a part of the social media team and the blog team.

My favorite hobby is definitely ringette but I also love other sports! Also, my favorite ice cream flavor is mint with chocolate chips.

Joanna

I’m currently studying in the Translational Medicine Master’s program at the University of Helsinki. I’m originally from Canada and I completed my Bachelor’s at the University of Toronto in Human Physiology major and Immunology and Physiology minors. One of my main passions includes increasing accessibility to scientific research. I find it very fulfilling to be able to simplify a complex concept enough to have those of different backgrounds understand it!

In this year’s iGEM team I’ll be working in the wet lab and I’m also a part of the graphic design team, the fundraising team, and the social media team.

My hobbies include cooking and anything superhero-related. Also, my favorite ice cream flavor is cookies and cream.

Rupesh

I’m currently studying in the Genetics and Molecular Biosciences Master’s program at the University of Helsinki. I'm originally from Chennai, India. I did my Bachelor’s in Biotechnology at Anna University, Chennai. My areas of interest include molecular biology and biochemistry.

In this year’s iGEM team I’ll be working in the wet lab and I’m also a part of the graphic design team and the blog team.

My hobbies are football, graphic design, and cooking (ever since I moved to Helsinki!). Also, my favorite ice cream flavor is chocolate.

Sofie

I’m currently studying in the Neuroscience Master's program at the University of Helsinki. I completed my Bachelor’s degree with a minor in statistics at the Victoria University of Wellington, New Zealand, before moving back home closer to my family. I have been interested in the brain for as long as I can remember. I find it fascinating how powerful yet fragile something can be. Our brains create our realities, and the way that happens is something I have been particularly interested in the past couple of years, in addition to neuropsychiatric disorders.

In this year’s iGEM team I’ll be working in the dry lab. I’m also a part of the graphic design team and the human practices team.

My hobbies include air yoga, running, and photography. Also, my favorite ice cream flavor is feijoa.

Vilma

I’m currently studying in the Master’s program of Biotechnology at Aalto University. I'm originally from Texas but have Finnish parents from Rovaniemi. I did my Bachelor of Chemical Engineering with minors in Biochemistry and Chemistry at the University of Minnesota, Twin-cities. The coolest thing I’ve ever learned is quantum tunneling. It blew my mind when I learned about it.

In this year’s iGEM team I’ll be working in the dry lab. I’m a part of the graphic design team and the social media team as well.

My hobbies include playing soccer (pre-covid) and jigsaw puzzles (covid). Also, my favorite ice cream flavor is vanilla.

…….

Moi kaikille! Aalto-Helsinki tiimimme on työskennellyt jo ahkerasti muutaman kuukauden ajan, ja nyt on vihdoin aika esitellä itsemme myös täällä blogin puolella. Olemme kuitenkin julkaisseet esittelykuvamme ja haastattelumme Instagramissa (käy seuraamassa meitä 😉), missä ne ovat edelleen nähtävissä. Tiimimme koostuu kymmenestä motivoituneesta opiskelijasta, jotka ovat kahdesta suomen huippuyliopistosta, Aalto yliopistosta ja Helsingin yliopistosta. Meillä kaikilla on hyvin erilaiset opiskelutaustat, mutta meitä yhdistää into kehittää tulevaisuuden ratkaisuja globaaleihin haasteisiin.

Sally, tiiminvetäjä

Opiskelen Mikrobiologian ja mikrobibiotekniikan maisteriohjelmassa Helsingin yliopistossa. Olen kotoisin Pohjois-Kaliforniasta, Yhdysvalloista. Opiskelin kandidaatiksi Kalifornian yliopistossa (UC Davis) ja valmistuin kesäkuussa 2020 Global Disease Biology -ohjelmasta, sivuaineenani Public Health Sciences. Olen kiinnostunut lääketieteellisestä mikrobiologiasta ja terveydenhuoltoon liittyvästä biotekniikasta, varsinkin virusten käytöstä geeniterapiassa, vaikka minulla ei ole vielä labrakokemusta tästä. Sanoisin, että varsinainen intohimoni kohdistuu koulutukseen ja toivon, että voin tulevaisuudessa parantaa kommunikaatiota tieteen ja kansanterveysalan työntekijöiden välillä.

iGEM-projektissamme työskentelen wet-lab-puolella, ja kuulun myös varainkeruu- ja blogitiimiin.

Mitä harrastuksiini tulee, rakastan patikointia, lentopalloa, kirjoittaa novelleja, kokeilla uusia reseptejä, ja tällä hetkellä opettelen soittamaan rumpuja. Lempijäätelömakuni on suklaahiput ja keksitaikina.

Emma, apulaistiiminvetäjä

Olen kotoisin Oulusta, josta muutin Helsinkiin opiskelemaan Energia- ja ympäristötekniikkaa Aalto yliopistoon. Ensimmäisenä opiskeluvuotena valitsin bioinformatiikan sivuaineen ja kiinnostuin kovasti kursseista, jotka olivat yhteydessä biotieteisiin. Tämä johti siihen, että muutin opiskelusuuntaustani ja hain Biologian kandiohjelmaan Helsingin ylopistoon. Siistein oppimani asia on evoluutio kokonaisuudessaan – mistä me tulemme, mistä elämä on alkanut ja kaikki tapahtumat jotka ovat johtaneet tähän hetkeen!

iGEM-projektissamme työskelen pääsääntöisesti dry-lab-puolella ja osittain wet-lab-puolella. Kuulun myös varainkeruutiimiin ja olen vastuussa meidän nettisivuista.

Harrastuksiini kuuluu patikointi, kokkaus, lukeminen, kutominen ja musiikki. Lempijäätelömakuni on kookos ja suolattu karamelli.

Anni

Opiskelen Genetiikan ja molekulaaristen biotieteiden maisteriohjelmassa Helsingin yliopistossa, ja aloitan Life Science Technologies -maisteriohjelmassa Aalto yliopistossa syksyllä. Olen kotoisin Porvoosta ja nykyisin asun Helsingissä. Mielenkiinnon kohteisiini kuuluu muun muassa genetiikka ja bioinformatiikka, ja haluaisin tulevaisuudessa päästä kehittämään uusia innovaatioita lääketieteen tai terveysteknologian edistämiseksi.

iGEM-projektissamme työskentelen pääsääntöisesti wet-lab-puolella ja osittain dry-lab-puolella. Kuulun myös some- ja blogitiimiin.

Harrastuksiini kuuluu musiikki, kitaran soitto, maalaaminen, lenkkeily ja muu urheilu. Rakastan viettää aikaa ulkona ja luonnossa. Lempijäätelömakuni on suklaa.

Anniina

Opiskelen Biosystems and Biomaterials Engineering -pääainetta Aalto yliopistossa, jossa suoritin myös kanditutkintoni Bioinformaatioteknologia-ohjelmasta. Olen aina ajatellut, että biologia on monimutkaista ja olen halunnut oppia miten biologiset systeemit toimivat molekyylitasolla. Uskon, että biofysikaalinen kemia ja ohjelmointi ovat auttaneet minua ymmärtämään biologiaa syvemmällä tasolla.

iGEM-projektissamme työskentelen dry-lab-puolella ja kuulun myös varainkeruutiimiin.

Mitä harrastuksiini tulee, tykkään todella kokata ja leipoa! Tykkään myös uida ja pyöräillä, ja opettelen miten käyttää pastelli- ja öljyvärejä. Lempijäätelömakuni on hasselpähkinä.

Enrique

Tällä hetkellä opiskelen Mikrobiologian ja mikrobibiotekniikan maisteriohjelmassa Helsingin yliopistossa. Olen kotoisin Madridista, Espanjasta. Opiskelin kanditutkintoni Bioteknologiasta, Madridin teknillisessä yliopistossa. Mielenkiinnon kohteitani ovat bioteknologia, musiikki, historia sekä taidehistoria.

iGEM-projektissamme työskentelen pääsääntöisesti wet-lab-puolella ja osittain dry-lab-puolella. Kuulun myös projektin varainkeruu- ja blogitiimiin.

Harrastuksiani ovat kitaran soitto, jalkapallo ja teatteri. Lempijäätelömakuni on suklaa.

Iiris

Olen molekyylibiotieteiden kandiopiskelija Helsingin yliopistosta, ja opiskelen tietojenkäsittelytieteitä sivuaineena. Olen erittäin kiinnostunut sekä molekulaarisesta biologiasta että tietojenkäsittelytieteistä, teknologiasta ja innovaatioista, ja haluaisin yhdistää kaikki nämä tulevaisuuden urallani.

iGEM-projektissamme työskentelen pääsääntöisesti dy-lab-puolella ja osittain wet-lab-puolella. Kuulun myös projektin some- ja blogitiimiin.

Lempiharrastukseni on ehdottomasti ringette, mutta rakastan myös muuta urheilua! Lempijäätelömakuni on minttujäätelö suklaahipuilla.

Joanna

Opiskelen Translational Medicine -maisteriohjelmassa Helsingin yliopistossa. Olen kotoisin Kanadasta ja suoritin kandidaatin tutkinnon Toronton yliopistossa, pääaineena ihmisen fysiologia ja sivuaineinani immunologia ja fysiologia. Yksi suurimmista kiinnostuksen kohteistani on lisätä tieteellisen tutkimuksen yleistä saatavuutta. Mielestäni on erittäin palkitsevaa, kun onnistuu yksinkertaistamaan monimutkaisen konseptin niin, että se on ymmärrettävä laajalle yleisölle!

iGEM-projektissamme työskentelen wet-lab-puolella. Kuulun myös graafisen suunnittelun tiimiin, ja varainkeruu- ja sometiimiin.

Harrastukiini kuuluu kokkaaminen ja kaikki supersankareihin liittyvä. Lempijäätelömakuni on keksit ja kermajäätelö.

Rupesh

Opiskelen Genetiikan ja molekulaaristen biotieteiden maisteriohjelmassa Helsingin yliopistossa. Olen kotoisin Chennaista, Intiasta. Opiskelin kandidaatiksi Anna yliopistossa Chennaissa. Kiinnostuksen kohteitani ovat muun muassa molekulaarinen biologia ja biokemia.

iGEM-projektissamme työskentelen wet-lab-puolella. Kuulun myös graafisen suunnittelun tiimiin ja blogitiimiin.

Harrastuksiani ovat jalkapallo, graafinen suunnittelu ja kokkaus (siitä asti kun muutin Helsinkiin). Lempijäätelömakuni on suklaa.

Sofie

Opiskelen neurotieteiden maisteriohjelmassa Helsingin yliopistossa. Suoritin kanditutkintoni psykologiasta tilastotieteen sivuaineella, Victorian yliopistossa Wellingtonissa, Uudessa-Seelannissa. Tämän jälkeen muutin takaisin Suomeen lähemmäs perhettäni. Olen ollut kiinnostunut aivoista niin kauan kuin muistan. On kiehtovaa, miten aivot ovat niin vaikutusvaltainen mutta hauras elin. Aivomme luovat todellisuutemme, ja tapa, jolla tämä tapahtuu on kiinnostanut minua jo useamman vuoden, neuropsykiatristen sairauksien lisäksi.

iGEM-projektissamme työskentelen dry-lab-puolella. Kuulun myös projektin graafisen suunnittelun ja yhteiskunnallisen vaikuttamisen tiimeihin.

Harrastuksiini kuuluu ilmajooga, lenkkeily ja valokuvaus. Lempijäätelömakuni on feijoa.

Vilma

Opiskelen Bioteknologian maisteriohjelmassa Aalto yliopistossa. Olen kotoisin Teksasista, mutta minulla Rovaniemeltä kotoisin olevat vanhemmat. Suoritin kanditutkinontoni Minnesotan Twin-Cities Yliopistossa, Chemical Engineering -ohjelmassa sivuaineina biokemia ja kemia. Siistein oppimani asia on kvanttitunnelointi. Sen oppiminen oli tajunnanräjäyttävää.

iGEM-projektissamme työskentelen dry-lab-puolella. Kuulun myös graafisen suunnittelun tiimin ja sometiimiin.

Harrastuksiini kuuluu jalkapallo (ennen korona-aikaa) ja palapelit (korona-aikana). Lempijäätelömakuni on vanilja.

#igem #aaltohelsinki

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contempoyanna · 4 years ago

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PPF Events (Past-Present-Future)

No matter who and what you are, there are certain happenings that happened in this world that may have affected the way we live right now. It does not really matter if we were alive at the time it happened, it still affects us. Have you ever thought about that? Ever thought about why the society you are living in has these certain standards, these methods, and issues? What may have influenced them or caused them to be as is? Well, you may have not but I have.

PPF Events, as I would like to call it, are global occurrences that, in my opinion, affected the life I am living right now; events that happened before I was even formed in my mother’s uterus, as I was growing up (and experiencing the awkwardness during puberty - yikes) and, of course, those that might have (unknowingly) an impact on my future.

With that, let me just start discussing these events that live rent-free in my mind, what they are, when (a bit of how) they happened and why I think it affects me.

Might wanna grab a snack and a cup of coffee while you read this, it’s going to be a while yeah.

Let’s start with the 1800s...

(photo: https://www.coveyclub.com/blog_posts/seneca-falls-convention-feminism/)

Feminism is one of the most known movements for women empowerment and gender equality.

Not even my parents were alive when this happened.

As I grew up and discovered more about this, I realized that the reason why women nowadays are slowly (but surely) being recognized as equals to men is because of a movement that happened by the 19th century (19th right?) and in New York - further proves that America was indeed a land of opportunity. Now, before I discuss why I think it affected me, let me clarify something. Feminism aka Women’s Rights Movement is meant to fight for equality, for women to be recognized as an equal to men. It is not meant to say that women are superior yet it is meant to say that women should be equal to men.

Some of you may not be aware but feminism has four waves, and in this post I am referring to the first wave that happened July 1848 in Seneca Falls, New York City.

It was THE conference that had 300 women discussing what their rights are socially, civil and religious. From what I have read, it was a fruitful meeting (well it wasn’t successful but it was somewhat fruitful). It was concluded with a long, long list of male-centric laws that demean a women’s self-esteem and self-respect. TLDR; These laws exclude women’s rights (to which I say no <3).

This wave was the foundation of how women today can walk freely and proudly say that they deserve the same rights to be respected and equally acknowledge their strengths as done to men. These were the women who encouraged and influenced many of us that we are not just to depend and be abject to our ‘partner’, we are more than that.

We are women, humans that deserve to be respected, to have civil rights and to be more than just a “wife”.

Interested? You can read more here Senaca Falls Convention & The Women’s Rights Movements.

1991′s Pinatubo Eruption

(photo: https://globalnation.inquirer.net/100047/filipinos-pinatubo-photo-named-among-greatest-of-all-time)

Pretty sure almost everyone, well at least every Filipino and neighboring countries, know about this event that was proclaimed as one of the greatest eruptions of all time. It was always taught during history -how unforgettable June 15,1991 is - because of its global reach and impact.

In fact, it was so great that the fumes it released changed global climates, causing some to drop a few degrees of the normal temperature and Asian countries to have a temporary shift in their rain patterns.

Why do I think this affected me? Well, I am a person of this Earth thus what affects the Earth affects me too. See, before Mount Pinatubo, global warming (I’m sure almost everyone of us is aware of this matter) has been a concern by many scientists and environmentalists alike. As many of the articles (although I only referenced the one I based on the most) I have read stated, for 60 - 70 years, the global temperatures continue to rise because of the emission of greenhouse gases.

The eruption of Mount Pinatubo injected particles (fumes?) of sulfur dioxide in the atmosphere which decreased the global temperatures for two (2) years, approximately. This event further proved that humans were - and still are - the main contributor to the continuous climate change and global warming we are experiencing.

TLDR; This global occurrence further proved that we are the ones destroying our home. It affects me, as it affects you, because what affects the Earth should affect us.

Want to know more? Read here: Pinatubo 25 Years Later

How about events as I was growing up?

#METOO Movement - 2006

(photo: https://news.harvard.edu/gazette/story/2020/08/challenge-of-archiving-the-metoo-movement/)

If you frequented on Twitter during 2016 and late 2017, you might be familiar with #MeToo.

Originally founded by Tarana Burke through using the phrase “me too” in MySpace (that’s something I haven’t heard in a long time), she thought of a way to help sexual crime victims and, at the same time, make people all over the world aware of how much of an impact sexual harassment has on the victim.

#MeToo movement aims to make aware how common sexual harassment, abuse and violence is through victims sharing their own experiences thus letting them know they are not alone.

How has this affected me? Well, personally I have been one who has experienced sexual harassment in (dare I say) minimal forms. Such as being catcalled, or even being sexually assaulted while commuting in public transpo.

Most sexual harassment or sexual assault victims find it hard to confess what had been done to them because of the different norms in their society, however the #MeToo movement tells you that you are not alone. That your voice should be heard, because you are not wrong. You were the one wronged.

Especially with how conservative our society is, where they usually blame the victim for how they dress or how they act which resulted to them being harassed or assaulted rather than the offender, it is a huge relief that there are people who would be there to fight for you in a way that you cannot for yourself.

Read more: Understanding the Me Too movement: A Sexual Harassment Awareness Guide.

2013′s Typhoon Haiyan

(photo: Manila Bulletin)

Here in the Philippines, Typhoon Haiyan is better known as “Yolanda” and to many of us (including my family) this has been one of the most traumatizing experience out of all the typhoons our country has experienced. Although our experience is not as bad as those in Tacloban, Leyte, it certainly was not the best either. Our place has never really been flooded - not even during Ondoy - but during Yolanda, flood washed into our house that we had to stay upstairs until it went down.

You would see debris, garbage and even some swimming rats. In addition to that, the strong winds could be felt and the loud thunder, followed by a bright lightning strike. It really was a scene that I would never forget. How much more to those who lost their family, their home, their source of income? Did this affect my life? Yes, greatly I can say. How? It opened my eyes to a lot of things.

First, was how unready we, as a country, were when calamities like this strike us. One would think that we would be prepared since our country is prone to strong typhoons such as this, yet we are not.

Other than that, according to the World Meteorological Organization (WMO), the typhoon was caused by human-induced climate change which is also a by-product of global warming. Add to that, the never ending garbage everywhere that we cannot seem to solve.

As I have said earlier, what affects the Earth, affects me. In this case, it directly affected me and my ‘kapwa’ Filipino, endangering thousands of lives and destroying a whole island’s worth of homes.

Read more: 2013 Typhoon Haiyan: Facts, FAQs, and how to help & UN: ‘Yolanda’ tops extreme events of 2013

Events that will (greatly) affect me in the future?

2020 - COVID-19 Pandemic

(photo: https://www.fda.gov/food/food-safety-during-emergencies/food-safety-and-coronavirus-disease-2019-covid-19)

None of us expected to spend our 2020 this way, but here we are. Stuck indoors because of a virus that has yet been cured or found an effective (and safe) vaccine.

Pretty sure a lot of us are affected with this pandemic, especially our futures. For students like us, you are either affected by this because you have to struggle in online classes (and in our country, trust me that’s a challenge) or due to personal matters, you would be taking a leap year from school or university.

For adults, like our parents, this has really been an event that has been heavy on financial load and struggling to spend money for our everyday needs. Especially since a lot of companies laid off on their employees due to economic circumstances and for the sake of the company itself.

I cannot say for sure, whether this pandemic has a good or bad effect on my future, but I can say that it is an experience that taught me a lot of things on how to handle difficult situations and gave me a rough idea on what I would be dealing with as a doctor in the near future.

Development of Nanotechnology

(photo: https://www.medicaldevice-network.com/comment/nanotechnology-medicine-technology/)

Nanotechnology sounds like something that came out of a sci-fi book but I’m telling you, it’s real. Various fields are developing ways to maximize this especially in the field of medicine.

What it is and how does it work you may ask?

This technology uses physics and molecular chemistry elements as a foundation, forming a functional system with unique characteristics that is engineered at a molecular level and occurs at nanoscale.

There are many applications of it as of today (in different industries too) yet what fascinates me the most is that nanotechnology may be one of the methods to cure cancer and prevent other diseases if properly utilized by medicine.

You may have noticed that I am focusing on the applications of nanotech in medicine but that is because I am going to be part of the medicinal field sometime in the future - which is basically why I’m biased.

Going back, according to the National Nanotechnology Initiative of the U.S., gold nanoparticles are currently being researched and clinically trialed as a potential treatment for all kinds of illnesses (especially terminal ones like cancer). Add to that, nanotechnology is to thank for the improved imaging and diagnostic tools we have that help in early diagnosis, individualized treatments and better success rates - therapeutically.

As promising as it sounds, keep in mind that it is a fairly young and new scientific discovery so it is bound to have many faults. However, as we age, technology also advances and improves its many faults along the way - for example, Artificial Intelligence (A.I.) and other robotic mechanisms.

Thus, I do believe that the discovery of this certain technology has a great impact not only on my future, but, as someone who will be working in the medicinal field, also the future of medicine itself.

Here’s a few articles that will inform you about nanotechnology in medicine:

The Future of Nanotechnology in Medicine, Benefits and Applications of Nanotechnology & Nanotechnology in Medicine: Technology Trends

In conclusion?

The world continue to advance towards (hopefully) better things. In my lifetime, these are some of the events that I believe made a great impact on my life.

I am pretty sure that we all have different global events that continuously affect the way we live, the way we are as a person.

Looking at it on another perspective, these occurrences may be a lesson for the future generation. A reference of what to do and what NOT to do (especially with how our government handled this pandemic).

How about you? What PPF events made an impact in your life?

#GEWORLD #personal #random thoughts #random opinion

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awakeningstar-posts · 5 years ago

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Food for thought: Connecting some dots on COVID-19

I am putting together this blog in response to friends and family who are looking for information outside of the mainstream news fear porn that we are subjected to everyday. I started doing my own research in February out of curiosity because my intuition told me something wasn't right.

Disclaimers: I used to work in public health and am by no means anti-vaccine, although I have newfound understanding of the concerns raised. I have voted democrat since 2012 and come from a liberal family. With that said, the narrative we are seeing playing out is not one that I can put my trust behind for reasons I will outline below. The more I learn the more I become skeptical of the global establishment narrative #wwg1wga

When the crisis jumped from China to the rest of the world in February/March, I was impressed with the global coordination to contain the virus. Closed borders, airport shut downs, quarantines, loan assistance for small businesses and unemployment relief for workers. Standard formula, applied globally. What a fantastic response by governments, including those who have turned a blind eye to the millions who die annually from diseases that could be prevented with existing life saving medicine, improved regulations on food and water supplies, and alternative medicines. But here we are in 2020 and all of a sudden, your health and mine are so important that they were willing to shut down economies. Had world leaders suddenly grown a heart or was there more to this story ?

In this post, I will not go into theories about the agenda. The truth is that I don't know. There are theories ranging from 5G, New world order, ID 2020, and more. I will refrain from making any theories but rather present facts that I have come across that had made me think there was more to the story than was being presented to us. My aim isn't to further any conspiracy theories. With that said I do not subscribe to the thought that an individual who thinks for him or herself is a conspiracy theorist, but rather someone seeking truth. As with all information, I urge you to do your own research and come up with your own conclusions.

1st question I researched: Was COVID-19 a natural virus that mutated from bats?

Information I came across: Francis Boyle interview stating that this was a bio-weapon. For information, Francis Boyle is a Professor of International Law at the University of Illinois College of Law. He drafted the U.S. domestic implementing legislation for the Biological Weapons Convention, known as the Biological Weapons Anti-Terrorism Act of 1989.

The interview was removed by youtube and recovered here by a youtube user: https://www.youtube.com/watch?v=U9KZjydtAWU

March 9: Mahmoud Ahmadinejad, Former President of Iran sends letter to UN Secretary General to investigate the potential of COVID-19 as a bio-weapon https://twitter.com/Ahmadinejad1956/status/1237072414841937920?s=20

More information pointing to a man-made virus:

Indian researchers publish study showing that it was unlikely to have a natural original because of its unusual similarities with HIV and Ebola. I read the study before it was taken down from this site: https://www.biorxiv.org/content/10.1101/2020.01.30.927871v2

Article on the censoring of this study: https://www.ccn.com/hiv-ebola-like-mutations-suggest-coronavirus-leaked-from-a-lab/

PR Luc Montagnier, French Virologist and Nobel Prize winner in Medicine states the virus came out of a lab and backs up censored Indian study. https://www.youtube.com/watch?v=usyQgPU-VrI

https://www.youtube.com/watch?v=durcHyxpFT4

Question 2: If this virus really was engineered, who made it ?

There is evidence pointing to the fact that there was a study conducted in 2015 on the coronavirus with US scientists and Chinese scientists from various American institutions and the Wuhan Institute of Virology.

Overview: https://www.thegatewaypundit.com/2020/05/updated-dr-fauci-likely-broke-us-law-funded-wuhan-lab-continue-coronavirus-projects-banned-us-2014/

US National Institute of health funded Coronavirus Study in 2015 (Notable partners : Harvard Medical School, University of North Carolina, Wuhan Institute of Virology see authors information): https://www.nature.com/articles/nm.3985#Sec1

Excerpt:

« On the basis of these findings, we synthetically re-derived an infectious full-length SHC014 recombinant virus and demonstrate robust viral replication both in vitro and in vivo. Our work suggests a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations. »

Response to the controversy of the 2015 US and China study:

https://www.nature.com/news/engineered-bat-virus-stirs-debate-over-risky-research-1.18787

Excerpt:

« The argument is essentially a rerun of the debate over whether to allow lab research that increases the virulence, ease of spread or host range of dangerous pathogens — what is known as ‘gain-of-function’ research. In October 2014, the US government imposed a moratorium on federal funding of such research on the viruses that cause SARS, influenza and MERS (Middle East respiratory syndrome, a deadly disease caused by a virus that sporadically jumps from camels to people).

The latest study was already under way before the US moratorium began (2015 study), and the US National Institutes of Health (NIH) allowed it to proceed while it was under review by the agency, says Ralph Baric, an infectious-disease researcher at the University of North Carolina at Chapel Hill, a co-author of the study. The NIH eventually concluded that the work was not so risky as to fall under the moratorium, he says.

But Wain-Hobson disapproves of the study because, he says, it provides little benefit, and reveals little about the risk that the wild SHC014 virus in bats poses to humans.

Other experiments in the study show that the virus in wild bats would need to evolve to pose any threat to humans — a change that may never happen, although it cannot be ruled out. Baric and his team reconstructed the wild virus from its genome sequence and found that it grew poorly in human cell cultures and caused no significant disease in mice.

“The only impact of this work is the creation, in a lab, of a new, non-natural risk,” agrees Richard Ebright, a molecular biologist and biodefence expert at Rutgers University in Piscataway, New Jersey. Both Ebright and Wain-Hobson are long-standing critics of gain-of-function research. »

Question 3: Is it a coincidence that the virus came out of Wuhan and not somewhere else in China?

A simple google search told me that Wuhan was home to the Wuhan Institute of Virology, which is a BSL 4-lab. The highest clearance level for research on dangerous pathogens. https://www.bbc.com/news/science-environment-52318539

US, UK, and Australia investigating the origins: https://www.express.co.uk/news/world/1270676/China-UK-US-Wuhan-virus-lab-coronavirus-origin-mystery-COVID-19-latest

https://www.foxnews.com/politics/australia-joins-us-china-coronavirus-pandemic

Thought: Assuming this was man-made and it as released by accident, does that matter right now, when we are dealing with a lethal virus and a pandemic?

Question 4: Is the coronavirus death toll including numbers of people who would have died of other diseases? *Disclaimer: I am in no way suggesting that this disease isn't real or that it hasn't been the cause of death for some. I do think we owe it to ourselves to get to the bottom of it so we can treat those who are sick, protect those who are vulnerable, and actually have proper plans for how we move forward.

May 9: Dr. Birx (former head of CDC's Global HIVAIDS dept) states: irx and others were frustrated with the CDC’s antiquated system for tracking virus data, which they worried was inflating some statistics — such as mortality rate and case count — by as much as 25 percent, according to four people present for the discussion or later briefed on it. Two senior administration officials said the discussion was not heated.

“There is nothing from the CDC that I can trust,” Birx said, according to two of the people. https://www.washingtonpost.com/politics/as-deaths-mount-trump-tries-to-convince-americans-its-safe-to-inch-back-to-normal/2020/05/09/bf024fe6-9149-11ea-a9c0-73b93422d691_story.html

BBC article on how to interpret Coronavirus death numbers, focused on UK data.

"Nearly 10% of people aged over 80 will die in the next year, Prof Sir David Spiegelhalter at the University of Cambridge points out, and the risk of them dying if infected with coronavirus is almost exactly the same. That does not mean there will be no extra deaths - but, Sir David says, there will be "a substantial overlap".

"Many people who die of Covid [the disease caused by coronavirus] would have died anyway within a short period," he says.

Knowing exactly how many is impossible to tell at this stage."

https://www.bbc.com/news/health-51979654

In Italy:

Prof Ricciardi (scientific adviser to Italy’s minister of health) added that Italy’s death rate may also appear high because of how doctors record fatalities.

“The way in which we code deaths in our country is very generous in the sense that all the people who die in hospitals with the coronavirus are deemed to be dying of the coronavirus.

On re-evaluation by the National Institute of Health, only 12 per cent of death certificates have shown a direct causality from coronavirus, while 88 per cent of patients who have died have at least one pre-morbidity - many had two or three,” he says.

https://www.telegraph.co.uk/global-health/science-and-disease/have-many-coronavirus-patients-died-italy/

In the US:

Dr. Scott Jensen, a Minnesota family physician who is also a Republican state senator, told "The Ingraham Angle" Wednesday that the Centers for Disease Control and Prevention's (CDC) guidelines for doctors to certify whether a patient has died of coronavirus are "ridiculous" and could be misleading the public

https://www.foxnews.com/media/physician-blasts-cdc-coronavirus-death-count-guidelines

CNN confirms CDC change in guidelines and 'probable cases' that will make the numbers spike on April 16, one month after the guidelines were changed and numbers already inflated since early March https://edition.cnn.com/2020/04/15/health/us-coronavirus-deaths-trends-wednesday/index.html

Thought: Wait if this is a pandemic and this virus is lethal to the point where the entire world has come to a standstill, why do they need to inflate the numbers when reporting it?

Question 5: Shouldn't we focus now on finding the treatment instead of being distracted by the origins?

Thought: What if the same people behind the origins are controlling the public narrative and have an agenda (profits for pharmaceutical companies, vaccine, insert the list of theories)?

In October 2019, Bill and Melinda Gates Foundation, World Economic Forum, and Johns Hopkins organized Event 201. A simulation of a coronavirus with exactly the same symptoms as the one we are seeing. Yes, I understand that the last couple pandemics were coronaviruses with the same symptoms. What made me scratch my head wasn't the fact that that the simulation happened or that their was a preparation for a potential outbreak. What shocked me is that the global leadership listened? Since when do people listen to public health officials and prioritize health over our economies? Health over money, wow that's new!

And here we are following the simulation play by play. I hope when we come out of this nightmare we will take a similar care for the millions who die of malaria, malnutrition, and more annually. Mobilize all resources until there are no more preventable deaths, because it's the number of deaths we want to reduce right? I digress...

Videos of the simulation can be found here: https://www.centerforhealthsecurity.org/event201/videos.html

I watched them so that I could know what was planned ahead. We did not end up seeing the internet blackout but censorship of any opposing views to the mainstream narrative is in full swing (videos taken down on youtube, scientists silenced, doctors silenced, citizen journalists silenced...)

On potential Vaccine:

See also link to potential vaccine agenda: https://awakeningstar-posts.tumblr.com/post/618825201145249792/mass-vaccination-agenda

See here for information on vaccines pushed by the Gates Foundation and video on the link between CDC, the pharmaceutical industry and Gates.

Why is Robert F Kennedy Jr, son of former US Attorney General and nephew to President Kennedy against Gates? Kennedy is an attorney and advocate for safe vaccines for children.

https://theduran.com/robert-f-kennedy-jr-exposes-gates-plan-to-control-global-health-policy-video/

Why did Microsoft patent a cryptocurrency system using body activity data in mid-March 2020. Would that require a vaccination and a chip? https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2020060606

Some information on Fauci's past: https://forbiddenknowledgetv.net/hivaids-research-pioneer-dr-judy-mikovits-blows-whistle-on-dr-fauci/amp/?__twitter_impression=true

Researcher nearing some “very significant findings” in his work on the coronavirus was found killed at his Pittsburgh-area home: https://www.washingtontimes.com/news/2020/may/4/bing-liu-university-pittsburgh-coronavirus-researc/

Plandemic (video has been pulled down multiple times, please search the subject in youtube to find a new link): https://www.youtube.com/watch?v=fsi9csLNb-Y&feature=youtu.be

Random insert but why aren't we talking about the head of Harvard University's Chemistry Department, Charles Liebert's who was arrested with two of his graduate students on their way to China in January? Why does he also have a link with an institution in Wuhan? Why did one of his grad students get arrested trying to smuggle 21 biological vials into China? https://www.justice.gov/usao-ma/pr/harvard-university-professor-and-two-chinese-nationals-charged-three-separate-china

Why is it that in the middle of this pandemic, the mainstream media is bent on attacking President Trump rather than coming together and finding solutions? We can play blame games later. If this really is a pandemic with the numbers being reported in the mainstream media, I would think they would be able to put their pettiness aside in the middle of a crisis.

Nobody took COVID-19 seriously at first. https://twitter.com/realDonaldTrump/status/1249858152578920449?s=20

I know some of us liberals have varying degrees of Trump derangement syndrome where everything the President does and said is viewed negatively. I know because I used to be like that and cognitive dissonance wouldn't allow me to disassociate with the image CNN gave me of him. Did it ever cross your mind that he isn't the enemy?

Question 6: Is Hydroxychloroquine a potential treatment or not?

Update June 2: “Surgisphere, whose employees appear to include a sci-fi writer and adult content model, provided database behind Lancet and New England Journal of Medicine hydroxychloroquine studies. It was also behind a decision by the WHO and research institutes around the world to halt trials of the controversial drug hydroxychloroquine.“ https://www.theguardian.com/world/2020/jun/03/covid-19-surgisphere-who-world-health-organization-hydroxychloroquine Remember when they said the Indian Scientists who discovered the HIV strains in coronavirus had not followed proper protocol, or that Dr. Rault’s study was ‘anecdotal’? And then they went and got data from a team of 6 including a sci-fi writer and adult content model. Let that sink in.

Update May 3: Meanwhile heroic medical professionals are coming out to state that hydroxychloriquiine is effective. Don't believe me, do your research. https://twitter.com/DocEvenhouse/status/1256765070245269505?s=20

On March 17 a study in France published findings of using an existing drug, Hydroxychloroquine as a potential treatment.

See study below :

Notable collaborators (Department of Virology, Biological and Pathological Center, Centre Hospitalier Universitaire de Nice, Infectiologie, Hôpital de l’Archet, Centre Hospitalier Universitaire de Nice, Thai Binh University of Medicine and Pharmacy)

In press March 17 https://www.mediterranee-infection.com/wp-content/uploads/2020/03/Hydroxychloroquine_final_DOI_IJAA.pdf

March 24 Dr. Fauci of the National Institutes of Health was asked March 24 whether the drug was considered a treatment for the novel coronavirus.

"The answer is no," he said, "and the evidence that you're talking about ... is anecdotal evidence."

Thought: Interesting statement, in response to a study not anecdotal evidence. Why not call for further studies to be done? We are looking to stop the spread of this lethal disease, no?

https://www.npr.org/sections/coronavirus-live-updates/2020/04/03/827177623/fact-check-premature-trump-continues-to-claim-drug-can-treat-coronavirus?t=1587336343410

Did Fauci already know about chloroquine as a potential treatment to coronavirus in 2005? https://pubmed.ncbi.nlm.nih.gov/16115318/

March 30th : FDA approves emergency use of Hydroxychloroquine https://www.fda.gov/media/136537/download

April 6th : Mixed messages sent to the US public about hydroxychloroquine https://www.youtube.com/watch?v=ceUDBPaQ77E

Mainstream media denies hydroxychloroquine as possible treatment.

Thought: We don’t know if it is THE treatment but given that an initial study has been conducted, does it not warrant that we explore a drug that could save lives ?

April 9 : Gates reiterates it could take another 18 months until we return to normalcy due to vaccine development. https://www.cnbc.com/video/2020/04/09/bill-gates-an-effective-covid-19-vaccine-is-at-least-18-months-away.html

April 9 : Studies begin testing if hydroxychloroquine is effective

April 10 : https://edition.cnn.com/2020/03/28/health/coronavirus-hydroxychloroquine-trial/index.html

April 15: https://edition.cnn.com/2020/04/15/health/new-french-study-hydroxychloroquine/index.html

Thought: I don't know if hydroxychloroquine is the most effective treatment, nobody will know until the studies are concluded but if there has been some success shouldn't we look at it? Why is CNN deciding before the results of the study that the drug is ineffective?

As of April 17 55 countries had placed orders for Hydroxychloroquine

Include : Afghanistan, Bhutan, Bangladesh, Nepal, Maldives, Mauritius, Seychelles, Sri Lanka, Dominican Republic, Madagascar, Myanmar, Zambia, Uganda, Burkina Faso, Niger, Mali, Democratic Republic of Congo, Egypt, Armenia, Kazakhstan, Ecuador, Jamaica, Marshall Islands, Syria, Ukraine, Eswatini, Chad, Republic of Congo, Senegal, Sierra Leone, Zimbabwe, France, Jordan, Kenya, Netherlands, Nigeria, Oman, Peru, Philippines, Russia, Slovenia, South Africa, Tanzania, UAE, Uzbekistan, Uruguay, Colombia, Algeria, Bahamas, Bolivia, Guyana, UK, US.

India is in the process of supplying anti-malarial drug hydroxychloroquine to 55 coronavirus-hit countries as grants as well as on commercial basis

https://www.indiatoday.in/india/story/india-sending-hydroxychloroquine-to-55-countries-will-not-procure-ppes-from-china-1667822-2020-04-17

May 10: https://www.forbes.com/sites/alexledsom/2020/05/10/hydroxychloroquinenumber-of-prescriptions-explode-in-france/#56428ce2180f

Numerous studies under way to further study the effects of hydroxychloroquine. Jury is out, but why the backlash on this potential drug?

And that's a wrap. Long but I wanted to show the full picture as I understand it. Think for yourselves, there is a lot of misinformation being spread by the mainstream media and alternative media. There is also a lot of censoring happening, doctors who previously were given platforms on mainstream media being called pseudo doctors for having differing views than the mainstream narrative, namely Dr. Oz and Dr. Drew. Funny how they weren't pseudo doctors when the same media channels were giving them platforms for the last decade. Ask yourself why information is being kept from us and as always, follow the money trails. Links between WHO, Gates, NIH, Fauci.

See Wikileaks drop on influence of Big Pharma on WHO (whose 2nd largest funder is Gates): https://www.collective-evolution.com/2020/04/19/wikileaks-highlights-the-influence-of-big-pharma-on-policy-making-within-the-world-health-organization/

See for Truth about vaccines and CDC and Big Pharma's role in past vaccine push and the censoring of scientific data raising concerns on vaccine safety: https://youtu.be/cHWeJ0f_o3A

After all this research, all I can say is do not blindly follow the official narrative, educate yourself and make informed decisions.

How many coincidences before mathematically impossible? What are the odds of that? Coincidence? #Q

As I mentioned before, I come from a liberal background, I currently do not follow any establishment party ever since Jimmy Dore showed me the light on the Corporate Democrats. I am just a truth seeker who wants everyone on this planet to live their best lives and that means freeing ourselves from a system that does not serve us.

Disclaimer: I am not suicidal and do not have suicidal thoughts. If something happens to me, it is not an accident. Stay safe. #WWG1WGA

More resources:

Follow Dr. Rashid Buttar on youtube: https://www.youtube.com/watch?v=KzXs1OHvItA

Robert F. Kennedy Jr on twitter: @RobertKennedyJr or look up his name to see articles people have tagged re Gates and vaccine agenda

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happyfestivalglitter-blog · 5 years ago

Link

Top Guidelines Of Psilocybin powder (Psilocin)BY

FEBRUARY 5, 2020

Psilocin and psilocybin are prohibited underneath the Ley Basic de Salud of 1984, which also particularly mentions psilocybin-that contains fungi as currently being coated because of the legislation, and mentions Psilocybe mexicana and Psilocybe cubensis especially.

the subsequent Raise in the general public’s recognition of microdosing arrived from the podcast job interview the writer gave with Tim Ferriss in March of 2015.

Psilocybin mushrooms don’t grow at the same speed. Diverse levels in the mushroom lifecycle comprise really variable quantities of the Lively compound. Modest mushrooms may possibly turn into more robust than completely developed mushrooms for the same number of dried bodyweight.

Microdosing isn’t magically beneficial If your thoughts is solely not attending to itself. Consideration is a peculiar factor. Listen to the brain and your body, as well as their interactions with the entire world about.

Due to this, it disappoints me that shulgin would propose that ethanol would yield pure psilocybin. proteins and nucleic acids also precipitate in chilly ethanol, question any molecular biologist.

Something is for certain – with microdosing, there’s no possibility of getting a “lousy journey” or suffering from extreme psychedelic results. Getting a microdose is the ideal way to be launched to psychedelics safely and securely and easily.

Should the mushrooms are brittle and effectively dry, they may be crushed with fingers. Cannabis grinders also operate very well. If they don’t seem to be entirely dry and you can continue to bend them, allow for them to dry even further.

Psilocybin in almost any variety is illegitimate. According to the Ukrainian Felony Code, fetal bodies of fungi containing psilocybin are considered a psychotropic substance, as well as the dose, which involves criminal legal responsibility, is 0.

And as our personal economies come to be a lot more summary, the mutual, cost-free assists and pleasures of relatives and Group lifestyle is going to be supplanted by a sort of displaced citizenship and by commerce with impersonal and self-intrigued suppliers…

As to your id in the crystals which were drifting all-around from the cooled Soxhlet receiver, from their becoming insoluble in ethanol, and white, and clear, I might guess you are seeing pure psilocybin.

Psychedelics which include psilocybin imitate the neurotransmitter serotonin once they enter the Mind – and we recognize that serotonin is found in increased levels in movement states.

Imagery found on prehistoric murals and rock paintings of recent-day Spain and Algeria implies that human usage of psilocybin mushrooms predates recorded heritage. In Mesoamerica, the mushrooms had extensive been consumed in read more spiritual and divinatory ceremonies in advance of Spanish chroniclers first documented their use while in the 16th century. In 1959, the Swiss chemist Albert Hofmann isolated the Lively principle psilocybin through the mushroom Psilocybe mexicana.

Have heard about this currently being accomplished with no filtration and evaporation/focus procedures along with the dosage was done by utilizing a simple shot glass value on the alcoholic combination. The consequences have been a potent 8hr journey.

02 Although psychedelic substances are already unlawful and prohibited from study in most nations up until eventually the earlier few years, several foremost gurus have picked up on exploration that started within the nineteen fifties and 60s.

Not Known Details About psilocybin powder

Psilocybin mushrooms are and keep on for use in indigenous New Planet cultures in spiritual, divinatory, or spiritual contexts. Reflecting the this means with the phrase entheogen (“the god within”), the mushrooms are revered as effective spiritual sacraments that present use of sacred worlds. Normally Utilized in tiny team Local community options, they improve group cohesion and reaffirm traditional values.

If there’s no vacuum filtering machine at hand, economical dust-pollen masks make good filters to the slurry. These can be obtained at components, drug and paint suppliers. They are frequently white or tan coloured, match more than the nose and mouth and therefore are held on on the facial area by a rubber band hooked up to your filter.

The majority of the comparatively handful of lethal incidents noted while in the literature that are associated with psychedelic mushroom use require the simultaneous usage of other medicine, Specifically Liquor. Most likely the most common cause of hospital admissions resulting from psychedelic mushroom utilization entail “terrible excursions” or stress reactions, wherein affected individuals become extremely anxious, confused, agitated, or disoriented.

Remarkable! Thank you for sharing. I will certainly Do that simply because creating them into powder offers them a lot more versatility.

With all these encouraging final results noted from whole doses, there’s motive to think that microdosing psilocybin could carry about likewise favourable lifestyle improvements.

Residing A prosperous lifetime ensures that we are true to our minds and also to our bodies. Isn’t it important to wake up Together with the Sunlight, to eat right and at the best occasions, to rest punctually, to remain Energetic and to go on walks, to comport oneself with dignity and honor, to deal with oneself and Other folks with regard and dignity?

When the mushrooms are brittle and successfully dry, they may be crushed with fingers. Cannabis grinders also do the job effectively. If they don’t seem to be entirely dry and website you may continue to bend them, enable them to dry even more.

We endorse drying a batch of mushrooms, grinding them into a powder, and measuring out about 0.1g of powder as your starter microdose. You could then change the amount appropriately just after your 1st try.

On cooling and with time, the free of charge base psilocybin molecules coalesce while in the liqueur and precipitate right into a whitish crystalline extract which falls to The underside of the storage vessel. The freebase Psilocybin molecules occur with each other rapid inside the neat alcohol.

Prepare your mushrooms slices on the dehydrating racks in one layer. Don’t crowd them an excessive amount of since you require that air flowing as a result of the many racks.

The riskiest point about microdosing is its likely illegal nature. Usually know about your neighborhood regulations and don’t undertake any unlawful routines.

Many people just sprinkle the calculated dose of the Psilocybin Mushrooms along with their food stuff. Some people such as the earthy taste of mushrooms a great deal that they “dip” a calculated micro-dose underneath the lip, and soon after some time swallow it.

Blend them with other spices for an amazing kick of flavor! The best part would be the mushroom powder is often created from any culinary mushroom (Be aware The range of colours you may reach with diverse mushrooms) and it truly is Tremendous effortless to get it done!

also working day tripper had been are you presently finding that this is fewer than 40 percent pure Have you ever completed this yourself and analyzed explained compound. and were did u get the concept you happen to be losing 50 % of one’s generate.

#psilocybin mushrooms

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inkofamethyst · 5 years ago

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January 19, 2020

Day 20 of being cute: I can say that I’ve been excused for the past few days because I’ve been nursing my poor ravaged mouth back to health. It’s not been a great time.

So! Got my wisdom teeth out Friday, spent most of that day numb and sleeping, only occasionally waking up to be spoon-fed ice cream and a pill by my mother. Spent most of Saturday sleeping too, with some occasional reading (finished Flowers for Algernon: 4/5) as ice packs were on and off my face every half hour for a twelve-hour period. Thought today was going to be a sleepy day too, but it wasn’t, just slow. I watched the Critical Role episode that I’d saved, but it was awfully funny and the laughter made my jowls hurt more. The endorphins were lovely but the pain.

By the way, I look like I ate a wasp.

And that’s been the weekend! I may do some sewing tomorrow (perhaps the last day of sewing and the dress will finally be put together?!) and pack some clothes for school. I’ll be leaving to go back this coming Saturday. I don’t really want to go but I do need to implement a schedule in my life. I also need to learn whether I’ll be able to learn from last semester’s mistakes. I’ll be learning new things in every single class this semester (Organic Chem, Calc 3, Anatomy 2, Humanities) so I’m really going to have to maintain some semblance of discipline without overly comparing myself to my hyper-productive and self-motivated DnD-friend. Cons of being a ~gifted~ kid: Self-motivation isn’t really a thing? Like, you get so used to the awards and rewards to the point where the fanfare following achievement becomes the motivation. So that fanfare becomes less frequent, motivation can either gradually shift to self-motivation, or can drop entirely. We’ll see how it goes, I guess.

You know, I haven’t had a right crush in a long while. Not since middle school, really. I don’t know why. And the only people I’ve ever been asked out by has been a guy who couldn’t spell punctuation (punkshoeashun was the spelling, I believe) and a guy who ended up being gay, so, yeah. I’m really not hitting home runs in the whole “guy” department. I’m hopeful that this year’s being cute (which roughly translates to “actually putting effort into my appearance on a daily basis and also trying to file down my rougher personality edges”) resolution thingy will help me out? Confidence is a big thing that I lack right now, and maybe it shows.

Anyway I bring up this crush thing because lots of people around me are being caught by the crush bug and I’m feeling... left out? Annoyed? Tired? I don’t know. Having a crush is exhausting and also something I just don’t want to be a part of right now. Yes, it’d be nice to feel ~desired~ but like?? So much more comes with that and I don’t think I can handle it. And you know what? Maybe that could change. Maybe something happens this semester (massively unlikely but, like,) and then I find out that I can handle it.

But then if/when the relationship ends, I don’t want to feel like I’m missing something. I don’t want to be on some endless chase because, at least for right now, romance isn’t what I immediately want out of life.

What do I want? Companionship. I just want friends right now. And I want to know that I’m making the right choice on my major. And I want to be okay with who I am.

Let’s unpack that second-to-last one, shall we? I’ve been meaning to this entire break. I’m a biochem major. Why? Well, if you were to ask me I’d say this scripted line that impresses most people “I enjoy molecular biology and I like learning the deeper meaning behind why things work the way that they do so a background in chemistry seems perfect for understanding biology, hence, biochemistry.” What do I plan to do with it? “Well, I’d like to continue my education to the doctorate level, likely with a PharmD, or perhaps a PhD, and then I’d like to do research.”

Easy answers.

But, for real. I’ve always been defined by my intelligence. I was never a real artsy kid, and even though I was good at English I knew that math and science were the “smart kid” subjects. So I tried to be good at them. And I was. Resilient too, especially when I wasn’t the top of the class. But I was still praised for my skills in the humanities, though I was still mediocre at best in the arts which I enjoyed, and rarely received recognition for my work in STEM. People would tell me that I was a smart kid. One of the brightest or whatever. And I wanted to prove them right by being the brightest in the toughest subjects. I never was. Math and chemistry never came to me easily. The humanities were hard, but I did enjoy them. Guiltily though, because they were the “easy” subjects. The ones people did if they couldn’t handle math and science. I had to prove that I could handle them. I still feel that need to prove myself.

But what if I’ve chosen wrong? What if this isn’t really what I want to do with the rest of my life and I’m just wasting four years and $100k in scholarship money (which, by the way, is lovely for purchasing $200 books for OChem) on the “safe” thing. I chose Biochem partially because of interest and partially because it sounded difficult. Impressive. Stately. Smart. No one immediately thinks of a history major as “smart.” Not dumb, necessarily, but not as smart as a comp sci, engineering, or chem major. But god I’d love to just learn about history all day long. That’d really be a paradise.

And what would I even do if I changed my major from STEM to humanities? What comes after college? Where would I find my place? What would my legacy be? (And, yes, even now as I ask, I remind myself that my legacy need not exist in the history books, but in the people I affect, though it’s not an easy thing to come to terms with that my name will be forgotten like so many others even if the results of my actions will live on in people’s hearts long after I’m gone.)

Does biochemistry excite me?

I don’t know yet. I’ve never taken a biochem class in my life. And I don’t understand half of the things that the biochem class descriptions mention. I’m afraid of getting excited? What if I don’t like it after all?

...The best way to know is to try, isn’t it?

Well, fine. I’ve got to try, I suppose, and I’ve got to try fast.

Things I’ve got to do: 1. Develop a resume. 2. Find a research opportunity somewhere for this summer. Whether it’s paid or not I’ve got to try out this whole biochem thing before it’s too late to change. 3. Start reading more in my field. I know I won’t be able to comprehend everything, but getting an idea about whether the realistic work in my field fascinates me or not (I can’t bank on the real-life equivalent of SHIELD picking me up after graduation to work with superhero physiology, okay?) will be crucial. And that’s that.

And if it turns out that I don’t like biochem after all then... well, that’s a bridge I’ll cross if I ever get to it.

And you know what? I’ve just got to keep reassuring myself that none of this means that my theatre dream is over. Perhaps a dream deferred. A personal project to work toward. And once I’ve got enough saved up that I can take a time and pursue the passion, then it’ll be okay. I just... I just need a backup plan. Whatever talent I’ve got is raw and unrefined. Refining will take some time. I’ll have to hustle for it.

Today I’m thankful for clarity of mind. I’m thankful for this long break which has allowed me time to rejuvenate and spend time with friends (Avatar binge starts Tuesday!!). All I need now is a deep breath before I head back into the thick of it all.

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hellacookies · 4 years ago

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LONG BUT IMPORTANT

The 2013 -2014 Ebola epidemic was extremely deadly to Africa.

The 1918 -1919 influenza outbreak was the most deadly pandemic in the last 250 years, killing 50-100 million humans.

Learning about these two spillover events, one can use lessons from history to predict what may happen in the future. I hate to say this, but we are not ready. Not ready as a nation, and certainly not prepared as a citizen to sacrifice to conquer any viral sickness or pandemic.

I strongly suggest two books to read and learn about the history of microbiology, virology, and epidemics: the Crisis in the Red Zone by Richard Preston and The Great Influenza by Barry. Both have precious insights and information and how epidemics and pandemics begin to spread, kill, and die out. The book details how the population and government deal or fail to deal with diseases. The parallels are striking.

We must take the lessons of history, or we are doomed to repeat the past.

In the next several paragraphs, I take passages from both books and incorporate them into my understanding of virology, immunology, molecular biology, and molecular genetics. The take-home point is one can prepare for an outbreak because what happens in an explosion is predictable.

As any epidemiologist will say, and I quote from an official in Brussels, “it’s always a change in behavior. Outbreaks end when people decide they’re going to end. “

Many viruses are Zoonotic, meaning these viruses typically exist in animals and, for some unknown reason, can spill over into the human species. When we have a spillover event, an outbreak occurs. This happened in Wuhan, China, with this virus. The virus escaped, leading to an outbreak.

Outbreaks lead to endemic, epidemics, or pandemics depending on spread.

Viruses are nothing more than a strand of DNA or RNA coated with a lipoprotein shell; there is disagreement if viruses are alive or dead. Viruses have a unique ability to invade a cell, take over the reproductive mechanism to enable viral reproduction. The virus, like every other organism in this world, only wants to survive, and it does it through its host. If the virus reproductive rate is extremely high such as Ebola, it can be too successful by killing off its host and extinguishing itself.

If the virus, the reproductive rate, or Ro (R naught) is too low, it can’t replicate fast enough; the species usually finds a way to snuff out the virus, and the disease retreats into the virosphere.

Influenza has a Ro is 1.1, meaning for every one person that has H1N1, it will infect 1.1 other people. This enables the the virus succeed and spread into the population, but not extinguish itself.

The higher the R number, the more contagious (infective) viruses are. An example: measles R number between 14 and 16. For one person having Measles, they can infect many. Measles is also a ‘dry virus’ and is genuinely airborne (see below).

Another question that enters people's minds is how fatal this contagion is? To answer this question, we look at the CFR or case fatality rate. Mathematically it is cases infected divided by deaths time 100. (For percentage, multiply).

For influenza, the flu, it is approximately 0.1 %. For COVID-19, it’s probably going to end up between 0.5 and 0.8%, for an Ebola Zaire 60%, for the mutated strain Ebola Zaire, A82V, the Macona strain, it’s close to 90% fatality if infected by even one tiny virion.

Let me explain some virology. I like to group viruses into two significant groups wet and dry. Dry viruses, like measles, are airborne. This means the virus can survive in the air independent of respiratory secretions or any other mechanism for hours. You could be in an elevator that someone was in half an hour ago, the person long gone, and you still contract measles.

Wet viruses, such as influenza, the common cold (many of these are beta coronaviruses), Ebola, Lassa fever, many others, require the virus to ‘hitch a ride’ on respiratory secretions. The latter two, it is also travel by sweat, feces, and urine.

This is why masks and PPE are so important, so vital in slowing the spread of wet germs. Parenthetically, masks are not enough and have to be used in conjunction with quarantine, social isolation, social distancing, and appropriate hygiene.

Once the virus enters the respiratory tract, it latches on to a receptor. In the case of coronavirus, it is the ACE2 receptor.

In the case of Ebola, a filovirus, it’s a cholesterol receptor. Either way, once the virus obtains entry to the human cell, it takes over cellular function and tells the cell to reproduce itself until the cell bursts open.

Many viruses are composed of a strand of RNA, ribonucleic acid. At the molecular level, the virus finds the ORF, open reading frame, or the three amino acid genetic sequence AUG, (Adenosine=Uricil=Guinine) and attaches its genetic code at that point.

This changes the cell function to replicate itself. The cell will continue to replicate and replicate more of the virus until the cell explodes and infect other cells; the process begins again. After multiple replications, the patient becomes ill and may succumb to the infection. Unfortunately, as in the case of coronavirus and especially measles, our patient is infectious and secreting virions, infecting you, before symptoms occur. In fact, in coronavirus, the patient is most infectious 24 to 48 hours before symptoms arise. That is a fact. This is why masks keep others safe.

RNA viruses tend to mutate at a fast rate. If you read about the 2014 Ebola epidemic in West Africa, you could trace the single amino acid mutation from patient to patient. It is termed genetic drift and usually does not cause any change in the infectivity or severity of the virus. It is the virus adapting to infecting humans and trying to perfect itself, make itself better at making you sick. All viruses drift. If it’s sudden and causes another strain, we call that a genetic shift.

In 1918 between the first wave and the second wave, the influenza H1N1 RNA virus did mutate and made the flu (don’t worry.....it’s just “the flu”) a perfect killing machine. The same thing happened with Ebola in 2014. A single amino acid shift in position 82 from Alanine to Valine, cause Ebola to become even more deadly, and the case fatality rate of 60% to jump to 90%. Ebola, unlike coronavirus, is exceptionally infectious through any type of sweat or body secretions. Many in Africa died, burying loved ones just coming in contact with the deceased.

You may wonder how the Ebola epidemic in Africa was overcome. It was not conquered by modern medicine; medieval techniques conquered it.

In the Macona triangle, where the new Ebola strain began, small villages practice reverse isolation and close themselves off from everybody else. No one in or out. They were “ preppers,” having 30 days of food and water in reserve.

Families sacrificed loved ones in to “doctors camps. “ run by the MSF. (french abbv for doctor’s without borders)

These camps run by local physicians, nurses, and complimented by MSF, separate the highly infectious patients from the rest of the population.

People today complain about wearing masks for this epidemic. My question is how would you feel if you had to give away your child, wife, father or mother, and put him or her in a doctor camp, knowing they would die alone because the patient had a fever? The alternative would be your entire family by destroyed by a virus too small to see.

The Ancient Rule was practiced, meaning villages would put the sick in a specific hut. The healthier sick, help the sicker bed ridden ones. Ebola is hemorrhagic fever, and many die by bleeding from the GI tract, dehydration and intractable vomiting, diarrhea.

Food and water will be left outside the shelter for two weeks. If anyone survived, they would join the rest of the village, after which the hut and bodies will be torched, and burned to the ground, then covered with dirt.

The virus was killed by fire, just like the Bubonic Plague in the 1300s. There were no burials, no ceremonies; the villagers realized how deadly this disease was. That’s how Ebola was conquered in Africa. I’m happy to say we now have a vaccine and medicines that are effective for Ebola. These vaccines are still being researched. Can’t happen here? Google Thomas Duncan or nurse Nina Pham, 2014, Ebola.

Duncan, died from Ebola in NYC in September 2014. He was on a NYC subway the day before he fell ill to the disease, sent home, returned to an ER and diagnosed.

No one has any idea how close we came to a significant Ebola outbreak in the United States in 2014. Only by the grace of God, and shear luck did we escape. (Oh, he had the Mecona strain with a mortality of 90%. We have 500 level 3 isolation beds in the entire USA. We are not ready.)

What does that have to do with coronavirus, you may ask?

As I also noted in the 1918 pandemic, the RNA virus also mutated and became more deadly. As you are aware of no vaccine was ever developed until recently; in fact, the virus was not identified until 2003. Cities that practiced quarantine, social distancing, mask usage, cities that closed their schools, shops, and movie theaters had fewer hospitalizations than cities that did not. That is a fact of history. Coronavirus has mutated. We have a D614G variant. The amino acid Aspartic acid, position 614, is now changed to Glycine. It is in the spike protein and binds more robust than the original virus. We do NOT know what this means or what it will do.

In conclusion, what I am trying to point out is the only way we’re going to beat a virus without any effective vaccine or cure is to do what was done years back throughout history. We quarantine, we stay home when we’re sick, we Social distance, and yes, wear a mask to protect not only yourself but others. Is it inconvenient? Yes, it is, but you know it’s more inconvenient putting on a level 3 hazmat suit to taking care of a coronavirus or Ebola patient in an ICU ( I have, and it’s not fun). It matters not whether it’s in Charleston South Carolina, Meadville, Pennsylvania, or in Sierra Leone, Africa. The virus does not care. It’s apolitical. It wants one thing and one thing only, to replicate and live. The virus is not a Republican or conservative, liberal, Democrat, or any monicker you wish to put on it

Understand this. The virus is not a single entity. It morphs, it changes, it hides, it deceives. It can mutate into a less or more deadly form. We can prevail, but it will involve sacrifice.

Unfortunately, it appears to me that many Americans care more about themselves than others, and are unwilling to sacrifice.

And it's just a virus, ”like the flu”?

Dr. Tom Arno MD FACC

#shinee #black lives matter #blm #naya rivera #the bad batch #queen #kelly preston #the old guard #gfriend #she ra #kpop #funny #good omens #meme #art #atla #atla zuko #tiktok #bts

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khalilhumam · 5 years ago

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‘While I breathe, I hope’: In conversation with Ali Gharavi of the #Istanbul10

New Post has been published on http://khalilhumam.com/while-i-breathe-i-hope-in-conversation-with-ali-gharavi-of-the-istanbul10/

‘While I breathe, I hope’: In conversation with Ali Gharavi of the #Istanbul10

‘The humanity of what I experienced in detention was humbling.’

A picture of #Istanbul10. Photo credit: Amnesty International via Wikimedia Commons [CC BY-SA 4.0].

Editor's note: This interview is republished through a partnership between Global Voices and IFEX. Read the full interview here. Ali Gharavi is a strategy and holistic security consultant working with human rights defenders, their organisations and communities. He is one of ten people — including İdil Eser, former director of Amnesty Turkey — who were arrested in Turkey in July 2017 at an information management and well-being workshop on Buyukada island. The hashtag #Istanbul10 was used in the sustained advocacy efforts that called for the dropping of all charges against them and their immediate release. In March 2020, ahead of an anticipated – but since postponed – verdict hearing, Ali spoke with IFEX Regional Editor Cathal Sheerin about how his experience being arrested in Turkey and jailed for four months has affected his life and informed his work. CS: How do you feel about the upcoming hearing?

I feel a combination of anticipation and anxiety. It’s been a roller coaster of emotions over the last almost three years and the verdict was supposed to have been reached at the last hearing. In terms of realistic outcomes, we’ve talked about two or three possibilities with our families, lawyers and the authorities in Sweden. I’ve been trying to keep my wits about me and not putting all my eggs in one basket, but we’re pretty optimistic that the outcome could be acquittal.

What makes you optimistic for acquittal?

I’m only nominally optimistic really because these things can turn on a dime. At the hearing before the last one, the prosecutor said that – of the ten of us plus Taner Kılıç – he would accept acquittal for five because of lack of evidence, but the rest he wanted to convict. I was in the acquittal group. All of us are quite adamant, however, about not having this ‘split’ decision.

Why do you think you were divided into two groups?

It’s really hard to say. Two of us in the acquittal group – Peter Steudtner and I – are not Turkish, so it’s possible that they want to remove the international angle from all of this. However, that’s just my speculation. It’s actually quite arbitrary, and I think this is partly because they have no evidence. It might even be a way to ramp this down: Let’s acquit half of them now and then acquit the rest in a trickle.

What has been the impact of your arrest, detention and trial on your family and friends?

This is a really important question for me, because we always tend to concentrate on the person who’s at the centre of the crisis. However, I compare the experience to a cluster bomb, where the first detonation is our arrest and the subsequent explosions take place in our families, among our friends and at our work as people discover what has happened. It’s not just confined to the ten or 11 who are in prison – it spreads like a virus, infecting everyone it comes into contact with. My partner went through great trauma, as did other members of my family, because of this. It can be all-encompassing for some people, as it was for me. It changes one’s life. You become a different person because of the trauma you endured: four months of being in various Turkish prisons leaves its footprint; and then, for your partner, there’s not knowing where her loved one is for two months, whether he is alive or not. My wife, Laressa Dickey, Peter’s partner, Magdalena Freudenschuss, and our colleague, Dan O’Cluanaigh, ended up creating a de facto response organisation that helped coordinate and inform the activities of all the other advocacy groups, such as IFEX. We called it the ‘Family Unit’ and its activities were informed by the work that Peter, Dan and I do – holistic security – which is about being actively aware that a crisis has many different aspects, including the digital footprint, physical security, health and psychological well-being. The ‘Family Unit’ did strategic planning and set objectives, such as caring for the families of the incarcerated and providing systematic communications so that each family had all the relevant information about their loved ones. They also developed protocols with our lawyers; some of this was as mundane as giving the lawyers our shoe and underwear sizes so that they could buy things for us. It’s basic, but that’s the stuff that makes it easier for the lawyers to do their actual work. The lawyers became the only mode of contact with us; my own lawyer is now my dearest friend because he was my lawyer and also my personal shopper, confidante, adviser and therapist.

Ali Gharavi. Photo credit: Annie Game

How aware were you when you were detained of the advocacy that was taking place on your behalf? What impact did it have on your morale?

Maintaining my morale was one of the biggest challenges for me. I was held at four different sites. At one point, they transferred us to the anti-terrorism headquarters for interrogation, which sounds like – and was – quite a harrowing experience. Then my family heard that, because of overcrowding, they’d placed me in a two-person cell with four others, two of whom were ISIS members. Obviously, when you hear that, it sounds like the most horrendous situation, but in reality it was actually a very supportive environment. Those two supposed ISIS members were actually just two religious boys who’d grown beards. I walked in to this very compact area where they’d all heard that these ‘super-spies’ were coming, and this young nineteen-year-old supposed ISIS member started speaking to me in German, knowing that I’d lived in Germany. He said: “You’re our elder, you’re our uncle, this is your home, whatever you want we’ll provide.” The moments which – from the outside – looked quite devastating, were sometimes actually moments of amazing solidarity. Most of our incarceration was spent in a maximum security prison. Because they supposedly thought we were super-advanced spies they put us in the Number Nine Prison, which has extra security. I had only one hour a week to see people – usually my lawyer or sometimes a diplomat. You begin to forget what the outside looks like and you assume that the outside doesn’t remember you either. But every week my wife would email details to my lawyer of everything that was being done for us, so that my lawyer could print it all out and pretend that it was a legal document (because that was the only thing I was permitted to look at). I’ve done letter-writing campaigns in the past, and I never knew for sure if they had any effect on the people who were in jail, but having been on the inside, I can say that those moments were life-saving. Sometimes my lawyer would search for my name on Twitter and print out all the tweets that had been posted that week about me; there was also this Twitter campaign, #haikusforAli, and demonstrations in Brussels, sit-ins in front of embassies. All of those moments reminded me that people on the outside were thinking of me and mobilising. I’m not exaggerating when I say that those were the things that saved me when I was in the depths of an abyss.

How has the experience affected how you work?

The kind of work I’d been doing was intended exactly for this kind of situation, where you need to pay attention to the whole person, not just their devices or the organisation’s activities. Because of my incarceration, I now understand that at a molecular level. For me, the whole experience has placed a higher premium on understanding people – who they are, where they are – as a big part of how we can actually help them regardless of whichever aspect of their work we’re trying to assist them with. One thing the experience revealed was how inadequately resourced and researched care and crisis response is: how do you care for not just the person incarcerated, but also his family, the community around him, his colleagues? Once the crisis is ‘over’ the assumption is that life goes on as usual, whereas there’s actually recovery that needs to be done. Often there’s also a massive financial burden due to legal costs and the inability to work for a while. After my release I went to Berlin and arrived into a very supportive debriefing environment. It’s a very privileged situation to be in – those ten days were very helpful in making me understand that I’d be going through this trauma and recovery and that it’s not just business as usual. There was a crowd-funder created for me so that I didn’t just have to drop back into work, and there was physical and psychological therapy too. I knew it intellectually, but now I know it viscerally, that just because you get released the trauma doesn’t just go away. It takes years to be functional again. People assume that when you recover you’re going to go back to being who you were, but that’s not true.

Would you ever return to Turkey?

It would be very difficult for me to feel safe there, but I would go, if only in order to ‘get back on the horse’. If the verdict doesn’t go the way we expect, then I’d be incarcerated if I turned up there, so I obviously wouldn’t return. I love Turkey – the people and the environment – and I feel like a big part of my life and friends is now off-limits to me. But I dream of when I’ll be able to go back, hug the people who were inside with me and eat baklava with them. As Cicero said: ‘While I breathe, I hope.’ The humanity of what I experienced in detention was humbling. Regardless of why those people were incarcerated with me, they – that young 19-year-old who spoke to me in German, and others – were an amazing source of inspiration and support. During the toughest times I’d be angry with them, but they were amazingly unwavering. I’ve heard via word of mouth that those two supposed ISIS members are now back with their families and all is well. I owe them a big debt of gratitude. Most of the time I was incarcerated alongside political prisoners who faced trial on specious charges, or who had been (and continue to be) detained for years on end as they wait for an indictment. And now we hear that despite the mortal threat of COVID-19 sweeping through the prison system, those prisoners will stay behind bars.

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technicaldr · 7 years ago

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The Future of Diabetes Management

One in eleven persons has to cope with diabetes worldwide on a daily basis

According to the latest estimates of the WHO, 422 million people suffer from diabetes worldwide – and the number is growing steadily. It means that one person in eleven has to manage the chronic condition on a daily basis, which might lead to stroke, blindness, heart attack, kidney failure or amputation. There are two types of diabetes: when the body does not produce enough insulin (type 1 diabetes) and when the organism cannot utilize the generated insulin (type 2 diabetes). While the latter can be prevented with conscious lifestyle choices, the former is a mystery to the medical community. But if someone has diabetes, that means having a constant companion.

In both cases, the treatment of the symptoms requires constant blood glucose control, which usually requires a kind of insulin intake at regular intervals, as well as blood pressure control and/or foot care. It is a truly technologically dependent condition: you need to monitor your blood glucose level, your blood pressure, your weight, follow a meal plan, test your blood every now and then. Luckily, there are so many digital health innovations for diabetes patients out there that diabetes management has been improving for years steadily – and it will significantly change in the coming years.

But technology in itself is insufficient: you need people to utilize it – and diabetes patients do. It is one of the largest and most motivated communities both online and offline, sharing their experiences on social media and other platforms. I believe one of the most amazing development is due to the diabetes community: the #wearenotwaiting movement advocated the absolutely efficient DIY artificial pancreas for so long and so successfully that the FDA approved it! Democratized healthcare at its finest!

1) Digital Contact Lenses

Although Google stopped developing its augmented reality glass, Google Glass, they did not give up on combining vision and technology. The search engine giant and Novartis signed an agreement in order to cooperate on the development of the digital contact lens patented in 2014. According to the plans, through the lens, you can get more information from the digital world plus it can measure blood glucose levels from tears as an added benefit.

Google and Novartis said the lens would contain a tiny and ultra slim microchip that would be embedded in one of its thin concave sides. Through its equally tiny antenna, it would send data about the glucose measurements from the user’s tears to his or her paired smartphone via installed software. Originally, the companies promised to put the digital contact lens around 2020 on the market, but Novartis Chief Executive Joe Jimenez in 2015 said that the contact lens would be on track to begin testing that year – and backtracked later.

Since then, there has been no news about the state of progress. However, in March 2017 Novartis Chairman Joerg Reinhardt talked down the chances of the project bringing visible results in the next couple of years, which is not very promising. [It’s] a long-term project, not something where we were expecting a breakthrough in the first couple of years. We certainly haven’t seen such a breakthrough. We don’t expect anything incredible in the next three to four years, Reinhardt said.

2) Gamification

Isn’t it more fun to make the diabetes monster happy than to boringly measure blood glucose level? There are already companies leveraging on your inner child. There are amazing applications for smartphones that can help you manage diabetes efficiently. MySugr, an Austrian company, released several applications that can add a little bit of gamification to the traditional diabetes management apps.

The company also developed the mySugr Junior App designed for kids to learn how to manage diabetes properly. It also enables parents to keep control over the therapy when they are not around the kid. The app looks like a game in which the children get points for every entry and the goal is to score a particular amount of points every single day.

3) Patient empowerment with big data

I have been quantifying my health for decades, I have even done so before the start of the wearable revolution: in an excel spreadsheet. But it’s not just l’art pour l’art data collection, I want to know everything about my organism in order to live longer and healthier in full mental, physiological and psychological capacity. So I am always happy to see inventions aiming to do the same.

Doug Kanter collected data about himself for a full year – blood sugar readings, insulin doses, meals, sporting activity etc. His company, Databetes was born out of his own experiences with diabetes. It helps patients better manage their condition by providing a good way for logging and measuring data, as well as a revolutionary concept to analyze the big data behind one person’s disease. Patients can support each other through social media channels and become coaches for each other. Look at sixuntilme.com for best practice examples.

4) Artificial pancreas

The bionic or artificial pancreas basically replicates what a healthy version of the organ does on its own, and it enables diabetes patients to live an easier life in a sustainable way. The device can measure blood glucose levels constantly and decide upon the insulin delivery itself. Engineers from Boston University have developed a bionic pancreas system that uses continuous glucose monitoring along with subcutaneous delivery of both rapid-acting insulin and glucagon as directed by a computer algorithm. However, it was not in commercial use.

As there was no single device on the medical market, which was able to monitor blood sugar and supply insulin automatically, creative persons invented a DIY version from existing technologies. Aas I mentioned above, a grass-root (social media) movement called #wearenotwaiting grew out of the initiative, who campaigned for the introduction of such artificial pancreas on the market for years persistently. One of the leading figures of the movement, Dana Lewis told me how an artificial pancreas eases everyday life. She has been using the device for almost two years by the time the US Food and Drug Administration finally approved it.

5) Food scanners

Currently, we have absolutely no idea, what we are eating – not to speak about what we should. Food scanners promised they will be able to tell how many grams of sugar a piece of fruit contains, or what the alcohol percentage of a drink is. Canadian TellSpec announced its aim is to develop a hand–held food scanner that can inform users about specific ingredients and macronutrients, but the market launch is unfortunately in delay. The Israeli company SCiO uses a technology similar to TellSpec’s but is designed to identify the molecular content of foods, medicines, and even plants. The company says that in milliseconds the ingredients and molecular make–up of the foodstuff will appear on the user’s smartphone. However, their promises have yet to be fulfilled, as the scanner, they introduced on the market does not exactly deliver what the demo did.

The Nima gluten-sensor (already on the market!) was named one of Time Magazine’s 25 best inventions of 2015. It is a portable, nicely designed gadget, which is able to tell you from a small food sample within two minutes, whether the food on your plate contains gluten. The firm also hopes to apply its technology to detect other food allergens, including peanuts and dairy.

6) Pocket-sized gadgets

When you live with diabetes, you get used to carting around with plenty of things such as meters, test strips, lancing devices. Therefore a pocket-sized gadget combining many meters and strips can mean change in life quality. The personalized, pocket-sized, all-in-one glucose meter called Dario can offer you that comfort. Moreover, it comes with a robust real-time mobile app to manage diabetes quickly, efficiently and accurately.

For over 25 years, Medtronic has been helping people with diabetes with its complex insulin pumps. With its latest, personalized, hybrid closed-loop system it seems to get a step closer to build its own artificial pancreas. In 2016, Medtronic announced its partnership with IBM Watson. The company introduced a demo for a new app at CES 2016 that will eventually give patients detail information about the rate of insulin delivered, the constantly fluctuating glucose level and carbohydrate intake information, alongside with information from wearable trackers or calendar details.

7) Wireless blood glucose monitor

Glucose monitors usually work like this: you prick your finger, you apply the drop of blood to the glucose strip, and soon you will get the results. For someone, who requires glucose monitoring more than 3-4 times per day, it is a troublesome process.

The medical company Abbott released a FreeStyle Libre wireless monitor especially for them. It is the first of a new class of glucose monitoring devices that use “flash” technology. The user has to wear a sensor on the upper arm, which measures glucose in the body water known as “interstitial fluid”. The FreeStyle Libre is very accurate, as it can do the measurement every minute!

8) Digital tattoos

Doctors have been searching for ways how to spare patients from the pain and trouble of blood glucose monitoring for years. Beyond wireless monitors, researchers have created an electronic skin patchthat senses excess glucose in sweat and automatically administers drugs by heating up microneedles that penetrate the skin. The prototype was developed by Dae-Hyeong Kim, assistant professor at Seoul National University and researchers at MC10, the company experimenting with all kinds of microchips and biostamps that can measure numerous vital signs simultaneously.

I hope that the technology will spread around soon and it will bring the era of wireless diabetes management to every patient.

So there are more and more technologies that can help people manage diabetes properly besides potentially future therapies such as new drugs or islet cell transplantation but it’s really time to manage diabetes in a gamified and comfortable way and I believe that the best gadgets and the best technological solutions are just yet to come.

Technical Dr. Inc.'s insight:

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[email protected] or 877-910-0004 www.technicaldr.com

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