#Non-Hodgkin’s Lymphoma and Chronic Lymphoma Treatment Market

[roseaa11]

Data Bridge Market Research analyses that the non-hodgkin’s lymphoma and chronic lymphoma treatment will exhibit a CAGR of around 7.75% for the forecast period of 2022-2029. Growing demand for targeted mode of therapies, surge in the research and development activities for the development of novel drugs and therapies, increasing cases of cancer and chronic diseases among population and increased expenditure for the development of healthcare infrastructure are the major factors attributable to the growth of non-hodgkin’s lymphoma and chronic lymphoma treatment market.

[stevenwilliam12]

Selective CXCR4 Inhibitor Market Insights: Trends, Target Population & Forecast to 2034

The CXCR4 chemokine receptor is a critical player in various physiological and pathological processes, including immune cell trafficking, stem cell homing, and cancer metastasis. Targeting the CXCR4 receptor has emerged as a promising strategy for the treatment of several diseases, particularly in oncology, hematological disorders, and HIV/AIDS. The market for selective CXCR4 inhibitors is witnessing substantial growth, driven by the increasing prevalence of cancer, autoimmune diseases, and infectious diseases, as well as advancements in molecular biology and drug development.

Market Size and Growth

The selective inhibitor of CXCR4 market is poised to experience robust growth, with an estimated compound annual growth rate (CAGR) of 12-15% through 2034. This growth is fueled by the increasing recognition of CXCR4 as a therapeutic target in various diseases, as well as the development of novel small molecule inhibitors, monoclonal antibodies, and peptides designed to block CXCR4 activation.

Several factors are contributing to the market's growth:

Rising Cancer Incidence: CXCR4 plays a pivotal role in the migration and metastasis of cancer cells, making it an important target for cancer therapeutics. Increasing cancer incidence, particularly in solid tumors such as breast cancer, ovarian cancer, and non-small cell lung cancer, is driving demand for CXCR4 inhibitors.

Advancements in Hematology: CXCR4 inhibitors are being explored for their potential to treat hematological disorders like acute myeloid leukemia (AML) and lymphoma. These disorders often rely on CXCR4 for immune cell trafficking, providing a strong rationale for the development of targeted therapies.

Infectious Disease and HIV: CXCR4 is also involved in the entry of HIV into host cells, particularly in CXCR4-tropic HIV strains. The development of CXCR4 inhibitors offers a potential therapeutic approach for treating HIV/AIDS, particularly in patients resistant to other treatments.

Stem Cell Therapy: CXCR4 is integral to the homing of stem cells to damaged tissues, especially in regenerative medicine. Inhibitors of CXCR4 are being studied to enhance stem cell mobilization, providing potential applications in bone marrow transplants and tissue regeneration.

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Target Population

The target population for selective CXCR4 inhibitors is diverse, including patients suffering from a variety of cancer types, hematological disorders, autoimmune diseases, and HIV infections. The primary target groups include:

Cancer Patients:

Solid Tumors: CXCR4 is involved in cancer cell migration, metastasis, and the establishment of secondary tumors. Solid tumors such as breast, ovarian, prostate, and non-small cell lung cancer (NSCLC) are key areas where CXCR4 inhibitors are being tested.

Hematological Malignancies: In diseases like acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and non-Hodgkin lymphoma, CXCR4 inhibitors can block the homing of cancer cells to the bone marrow, thereby disrupting tumor growth and improving patient outcomes.

HIV/AIDS: CXCR4 inhibitors can prevent the entry of HIV into host cells, making them an important treatment option, especially for patients with CXCR4-tropic HIV strains that do not respond to traditional antiretroviral therapy.

Autoimmune Diseases: CXCR4 plays a role in the trafficking of immune cells to sites of inflammation, making CXCR4 inhibitors potential treatments for autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

Stem Cell Mobilization: CXCR4 inhibitors are also being explored in regenerative medicine, particularly for hematopoietic stem cell mobilization. These therapies are being studied for their potential to improve outcomes in bone marrow transplantation and other regenerative treatments.

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Competitive Landscape

The competitive landscape of the selective CXCR4 inhibitor market is marked by significant investment in research and development by both large pharmaceutical companies and specialized biotech firms. Key players in this market include:

Genzyme (Sanofi): Genzyme, a leader in rare disease treatments, has developed Mozobil (plerixafor), an FDA-approved CXCR4 inhibitor used to mobilize hematopoietic stem cells in patients undergoing stem cell transplants. This product is already commercially available and represents a significant player in the market.

Janssen Pharmaceuticals (Johnson & Johnson): Janssen is actively involved in the development of CXCR4 inhibitors for hematological malignancies, including AML. The company is investigating novel inhibitors that target CXCR4 in combination with other cancer therapies.

Bayer: Bayer has been working on CXCR4-targeting drugs for cancer therapy, particularly focusing on solid tumors and hematological cancers. The company is exploring the combination of CXCR4 inhibitors with existing therapies like chemotherapy and immunotherapy.

Pfizer: Pfizer is developing selective CXCR4 inhibitors for various indications, including cancer and HIV/AIDS. The company is particularly focused on the use of CXCR4 inhibitors as a means of disrupting tumor metastasis.

Verastem Oncology: Verastem is focused on developing novel therapies for cancer, including CXCR4 inhibitors that are currently undergoing clinical trials for their potential in treating ovarian cancer, pancreatic cancer, and other solid tumors.

X4 Pharmaceuticals: X4 Pharmaceuticals is a clinical-stage biotechnology company dedicated to the development of CXCR4 inhibitors for treating rare diseases, particularly focusing on the WHIM syndrome (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis), a rare genetic disorder involving CXCR4 dysfunction.

Market Forecast - 2034

The market forecast for selective CXCR4 inhibitors through 2034 indicates strong growth, with the market anticipated to reach $2.5 billion to $3 billion by 2034. Several factors will contribute to this growth:

Increasing Applications in Oncology: CXCR4 inhibitors are expected to become an important part of the immuno-oncology landscape, particularly when used in combination with immune checkpoint inhibitors or other cancer therapies. Their potential to inhibit metastasis and improve tumor microenvironments will drive demand.

Expansion into Autoimmune Diseases: As research reveals the potential of CXCR4 inhibitors in treating autoimmune conditions, the market will expand beyond cancer and HIV to include therapies for diseases like rheumatoid arthritis, lupus, and multiple sclerosis.

R&D and Clinical Advancements: With many ongoing clinical trials, the approval of new CXCR4 inhibitors for a variety of indications is expected to accelerate, providing new treatment options for patients and expanding the market for these drugs.

Increased HIV Treatment Options: The continued development of CXCR4 inhibitors for HIV/AIDS, particularly for patients with drug-resistant strains, will contribute significantly to market growth, especially as newer, more potent inhibitors come to market.

Global Expansion: As healthcare infrastructure improves in emerging markets, the adoption of CXCR4 inhibitors is expected to increase, particularly in oncology and HIV treatments.

By 2034, the selective CXCR4 inhibitors market is expected to be a multi-billion-dollar industry, offering new treatment options for a wide range of conditions and significantly impacting the therapeutic landscape for cancer, autoimmune diseases, and HIV.

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Conclusion

The selective CXCR4 inhibitors market is poised for rapid expansion, driven by advancements in drug development, an increasing patient population across multiple therapeutic areas, and the promising potential of these inhibitors in oncology, hematology, autoimmune diseases, and HIV treatment. With a competitive landscape rich in innovation and clinical progress, the market is expected to grow substantially by 2034, providing new therapeutic avenues for patients and reshaping the treatment options for several critical diseases.

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[delveinsight12]

CD20 Market Size, Target Population, Competitive Landscape & Market Forecast - 2034

The CD20 market represents a vital segment in oncology and autoimmune disease therapeutics, driven by the role of CD20-targeting drugs in treating conditions like non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), and rheumatoid arthritis.

CD20 Market Size and Forecast

The CD20 drug market is projected to grow significantly, influenced by rising global cancer incidence, the expansion of biologics, and ongoing innovation in monoclonal antibody (mAb) therapies. Growth is particularly notable in regions like the U.S., the EU4 (France, Germany, Italy, Spain), the UK, and Japan. Increased awareness, enhanced diagnostics, and an aging population also contribute to the market’s expansion. This market is expected to achieve substantial valuation by 2034 due to upcoming therapeutic launches and improved access to treatments.

Read more @ https://www.delveinsight.com/report-store/cd20-market-forecast

CD20 Target Population

The primary target population includes individuals diagnosed with B-cell malignancies and autoimmune conditions. Non-Hodgkin lymphoma and chronic lymphocytic leukemia patients form the largest share of this population. Enhanced diagnostic methods are broadening the scope of the addressable market.

CD20 Market Competitive Landscape

The competitive landscape is robust, dominated by major players such as Roche (with Rituxan/MabThera and Gazyva/Gazyvaro), Novartis, and emerging biosimilars. Innovations include new monoclonal antibodies and combination regimens integrating CD20-targeting therapies with CAR-T cells or small-molecule inhibitors.

Additionally, the emergence of biosimilars is introducing competitive pricing dynamics, fostering accessibility in markets with constrained healthcare budgets.

CD20 Market Market Future Outlook

Ongoing clinical trials for novel CD20 inhibitors aim to address unmet needs, such as reducing side effects and increasing efficacy in refractory or relapsed cases. Combination therapies, particularly those integrating immune checkpoint inhibitors, represent a promising avenue. Regulatory approvals and adoption in emerging markets will also shape the market trajectory.

For an in-depth report, you can explore DelveInsight's dedicated resource on the [CD20 Market Forecast - 2034](https://www.delveinsight.com/report-store/cd20-market-forecast).

[laocommunity]

Revolutionizing cancer treatment: A comprehensive overview of Rituxan (rituximab) Drug Market, Impactful Strategies, and Forecast to 2030

Revolutionizing cancer treatment: A comprehensive overview of Rituxan (rituximab) Drug Market, Impactful Strategies, and Forecast to 2030 Revolutionizing cancer treatment: A comprehensive overview of Rituxan (rituximab) Drug Market, Impactful Strategies, and Forecast to 2030 Cancer is a devastating disease that affects millions of people around the world, causing physical and emotional pain for both patients and their loved ones. For decades, researchers and scientists have been working tirelessly to develop treatments to combat this disease. One such treatment that has proven to be incredibly effective is Rituxan (rituximab). Rituxan is a type of immunotherapy drug that targets cancer cells by binding to a specific protein on their surface. This causes the cancer cells to die, while leaving healthy cells unharmed. Rituxan has been approved by the US Food and Drug Administration (FDA) for the treatment of several types of cancer, including non-Hodgkin’s lymphoma and chronic lymphocytic leukemia. The Rituxan Drug Market The Rituxan drug market has experienced significant growth in recent years. According to a report by Transparency Market Research, the global market for Rituxan was valued at over $7 billion in 2018, and is expected to reach nearly $10 billion by 2026. This growth has been driven by a number of factors, including an increase in the prevalence of cancer, advancements in medical technology, and an aging population. One of the key drivers of the Rituxan drug market has been the increasing use of immunotherapy in cancer treatment. Immunotherapy is a type of treatment that uses the body’s own immune system to fight cancer. Rituxan is one of the most effective immunotherapy drugs available, and is used in combination with other treatments such as chemotherapy to provide maximum benefit to patients. Impactful Strategies In order to continue the growth of the Rituxan drug market and improve patient outcomes, there are several impactful strategies that can be implemented. One of the most important strategies is to increase awareness of Rituxan among physicians and patients. This can be done through targeted marketing campaigns, educational materials, and outreach programs. Another strategy is to continue investing in research and development to improve the effectiveness and safety of Rituxan. This includes exploring new applications of the drug, such as in the treatment of autoimmune diseases. By continuing to innovate and improve, Rituxan can remain at the forefront of cancer treatment. Finally, it is important to make Rituxan accessible to as many patients as possible. This includes working with insurance companies and healthcare providers to ensure that the drug is covered by insurance, as well as exploring alternative pricing models to make the drug more affordable. Forecast to 2030 Looking ahead to the next decade, the Rituxan drug market is expected to continue its growth trajectory. According to a report by Global Market Insights, the market is projected to reach $9.5 billion by 2030. This growth will be driven by factors such as an increasing incidence of cancer, advancements in medical technology, and a growing aging population. In addition, new applications of Rituxan may be discovered, expanding the market even further. For example, there is ongoing research into the use of Rituxan in the treatment of autoimmune diseases such as rheumatoid arthritis and lupus. Conclusion Rituxan has revolutionized cancer treatment, providing a highly effective and safe option for patients with certain types of cancer. As the demand for cancer treatment continues to grow, the Rituxan drug market is poised to continue its impressive growth trajectory. By implementing impactful strategies and continuing to innovate, Rituxan can remain a leader in cancer treatment for years to come. #BUSINESS Read the full article

[mediwinpharma]

Top Demand Drug companies in India in the Last Decade

Over the past decade, the demand for drug companies in India has significantly increased, reflecting the country's evolving healthcare industry. In fact, a report by Statista indicates that the Indian healthcare and pharmaceuticals sector is anticipated to experience an extraordinary growth rate of 754% between 2017 and 2060.

As India emerges as a major player in the pharmaceutical industry, it is critical to understand the demand for various drugs in the country. It provides valuable insights into the health concerns of the people, the shifting demographics, and the evolving medical requirements.

So, read the article below to gain in-depth knowledge about high-demand drugs in India and the factors influencing this demand. This knowledge can help drug companies to focus their R&D and production to cater to the specific needs of the Indian market.

Top 8 Demand Drugs in India

Some of the best drugs in India and their uses are given below:

1. Humira

Humira (adalimumab) is a widely used biological medication known for its effectiveness in treating various conditions. It functions as a tumor necrosis blocker, which helps suppress the immune system by blocking the activity of factor-α (TNF). TNF is a protein associated with inflammation and autoimmune diseases.

Uses

Treats rheumatoid arthritis in adults.

Indicated for adults with hidradenitis suppurativa (HS).

Tackles chronic plaque psoriasis.

Treats non-infectious intermediate, posterior, and panuveitis.

Approved for adult patients with active ulcerative colitis.

Used to reduce signs and symptoms of active ankylosing spondylitis.

2. Keytruda

Keytruda is a cancer medication that contains the active substance pembrolizumab. It belongs to a class of drugs known as immune checkpoint inhibitors. Keytruda blocks a protein called PD-1 in immune cells. This allows the immune system to recognize and attack cancer cells.

Uses

Treats advanced or metastatic melanoma.

Treats advanced NSCLC.

Treats children with classical Hodgkin lymphoma.

Treats advanced renal cell carcinoma.

Used in combination with chemotherapy or other cancer medicines to treat oesophageal cancer.

Prevents blood clots in cases like broken bones, immobility, surgeries, etc.

3. Eliquis

Eliquis is a prescription medication that belongs to the class of drugs known as anticoagulants or blood thinners. It is considered an anticoagulant because apixaban is its active ingredient. Eliquis is FDA-approved for treating and preventing dangerous blood clots that can block blood vessels in the body.

Uses

Treats deep vein thrombosis (DVT).

Prevents stroke.

Treats pulmonary embolism (PE).

Reduces the risk of systemic embolism.

Avoids thromboembolic events in individuals with chronic kidney disease.

Used as an anticoagulant therapy during cardiac catheterization procedures

4. Revlimid

Revlimid is a medication that contains the drug lenalidomide. It is a thalidomide analog, an immunomodulatory drug (IMiD) with various putative molecular targets and biological effects. Revlimid is primarily used to treat multiple types of cancers affecting blood cells.

Uses

Used in combination with dexamethasone for the treatment of multiple myeloma.

Used as maintenance therapy after an autologous hematopoietic stem cell transplant (auto-HSCT).

Treats lymphoplasmacytic lymphoma.

Used off-label for the treatment of systemic light-chain amyloidosis.

Tackles myelodysplastic syndromes.

Used in combination with rituximab to treat follicular and marginal zone lymphoma.

5. Imbruvica

Imbruvica is a medication available in tablet and capsule forms that are taken orally once a day. Its active ingredient is ibrutinib. Ibrutinib works by inhibiting specific proteins in cancer cells, slowing their growth, and preventing the spread of cancer.

Uses

Treats mantel cell lymphoma (MCL).

Treats chronic lymphocytic leukemia (CLL).

Tackles small lymphocytic lymphoma (SLL).

Treats waldenström's macroglobulinemia (WM).

Manages chronic graft versus host disease (cGVHD).

Prescribed off-label to diffuse large B-cell lymphoma (DLBCL).

6. Stelara

Stelara is a highly effective medication that contains ustekinumab. Ustekinumab is a monoclonal antibody derived from immune system cells. It is specifically designed to target and alleviate the symptoms of various inflammatory conditions associated with immune system dysfunction.

Uses

Provides relief for people suffering from this autoimmune skin condition.

Treats psoriatic arthritis for adults.

Deals with the challenges of moderate to severe Crohn's disease.

Treats adults with this type of inflammatory bowel disease.

Used off-label in the treatment of active systemic lupus erythematosus.

Used for investigational purposes of hidradenitis suppurativa.

7. Xarelto

Xarelto (rivaroxaban) is a medication also classified as a blood thinner. It works by inhibiting the activity of Factor Xa, an enzyme involved in blood clot formation. While Xarelto does not thin the blood, it helps prevent the formation of blood clots and reduces the risk of strokes and systemic embolisms in certain medical conditions.

Uses

Reduces the risk of stroke and systemic embolism with nonvalvular atrial fibrillation.

Treats and maintains drugs for deep vein thrombosis (DVT).

Reduces the risk of recurrence of pulmonary embolism.

Prevents blood clot formation in patients suffering from heart failure, respiratory disease, or infectious diseases.

Used as a prophylactic treatment to prevent blood clots in patients with cancer.

Prevents the recurrence of ischemic events, such as heart attacks or peripheral artery disease

8. Opdivo

Opdivo is an immunotherapy drug that belongs to a class of medications known as checkpoint inhibitors. It targets the PD-1 receptor, found on the surface of T cells, the immune cells responsible for fighting cancer. PD-1 helps regulate immune responses in healthy tissues, but cancer cells can exploit this mechanism to evade immune attacks. Opdivo blocks the interaction between PD-1 and PD-L1/PD-L2 molecules in cancer cells. This blockage enables T cells to recognize and destroy cancer cells effectively.

Uses

Treats advanced melanoma.

Treats non-small cell lung cancer.

Used in combination with ipilimumab for newly diagnosed malignant pleural mesothelioma.

Treats adult patients with classical Hodgkin lymphoma.

Treats patients with recurrent or metastatic head and neck squamous cell carcinoma.

Treats with microsatellite instability-high (MSI-H) or mismatch repair-deficient (dMMR) metastatic colon.

Factors that Impact the Demand for the Drugs

Here are four key factors that impact the demand for drugs:

1. Disease Prevalence and Epidemiology

The prevalence of diseases and their impact on the population greatly influence the demand for drugs. The burden of chronic diseases, or infectious outbreaks, shapes the market for specific medications to treat and manage these conditions.

2. Demographic Changes

Changing demographics, such as aging populations and urbanization, play a crucial role in drug demand. Different age groups have varying healthcare needs, and understanding demographic shifts helps target drug development and delivery strategies accordingly.

3. Economic Factors

Economic factors, including income levels, affordability, and healthcare expenditures, substantially impact drug demand. If medicines are expensive or not affordable, people may struggle to access their prescribed treatments. The cost and accessibility of medications greatly affect the choices people make and their ability to follow through with the necessary treatments.

4. Government Policies and Regulations

Regulatory frameworks, pricing regulations, reimbursement policies, and intellectual property rights all affect the availability, accessibility, and affordability of medicines. This further influences its demand in the market. Understanding and navigating these factors is crucial for ensuring that drugs are accessible and affordable to those who need them.

The Bottom Line

In conclusion, understanding the demand for drugs in India is vital for pharmaceutical companies, policymakers, and healthcare providers. By now, you must be aware of the factors that significantly impact drug demand. By aligning their strategies with these factors, stakeholders can meet the evolving healthcare needs of the Indian market effectively.

Moreover, if you're looking for a trusted name in the pharmaceutical industry for reliable and high-quality medications, consider Mediwin Pharmaceuticals. They have been one of the top pharma companies serving India since 1990. It is among the top pharmaceutical manufacturing companies in Ahmedabad because they facilitate effective medications for chronic conditions, specialized therapies, and preventive care.

So, visit Mediwin’s website today to discover its diverse product portfolio!

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[aartichede08]

Targeted Cancer Therapies Market Is Witnessing Significant Growth Owing To Rise In Incidence Rate Of Cancer

Targeted therapies, which include monoclonal antibodies and small molecule inhibitors, have significantly changed the treatment of cancer over the past 10 years. These drugs are now a component of therapy for many common malignancies, including breast, colorectal, lung, and pancreatic cancers, as well as lymphoma, leukemia, and multiple myeloma. The mechanisms of action and toxicities of targeted therapies differ from those of traditional cytotoxic chemotherapy. Targeted therapies are generally better tolerated than traditional chemotherapy, but they are associated with several adverse effects, such as acneiform rash, cardiac dysfunction, thrombosis, hypertension, and proteinuria. 

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TARGETED CANCER THERAPIES MARKET OUTLOOK

The global Targeted Cancer Therapies Market Is Witnessing Significant Growth Owing To Rise In Incidence Rate Of Cancer, minimal adverse effects and high adoption rate. There has been tremendous innovation over the past decade with the emergence of new drugs with very promising efficacy, along with increasing adoption of precision medicine technologies, as well as advanced monitoring techniques such as liquid biopsy. The use of targeted therapy has markedly changed outcomes for some diseases. Imatinib has had a dramatic effect on chronic myeloid leukemia, and rituximab, sunitinib, and trastuzumab have revolutionized the treatment of non-Hodgkin’s lymphoma, renal cell carcinoma, and breast cancer, respectively. Targeted therapy also introduces new economic considerations. Substituting oral small molecule inhibitors for traditional chemotherapy eliminates some treatment costs, including those associated with vascular access and intravenous infusions.

TARGETED CANCER THERAPIES MARKET SEGMENTAL OVERVIEW

The report analyses the global targeted cancer therapies market based on type, cancer type, end user and geography.

TARGETED CANCER THERAPIES MARKET BY TYPE

Based on type, the market is categorized into angiogenesis inhibitors, apoptosis inducers, gene expression modulators, hormone therapies, immunotherapies, monoclonal antibodies and signal transduction inhibitors. Monoclonal antibodies exert their anticancer effects through a variety of mechanisms including; by recruiting host immune functions to attack the target cell; by binding to ligands or receptors, thereby interrupting essential cancer cell processes; or by carrying a lethal payload, such as a radioisotope or toxin, to the target cell.

TARGETED CANCER THERAPIES MARKET BY CANCER TYPE

By various cancer types, the global targeted cancer therapies market is segmented into breast cancer, colorectal cancer, gastrointestinal, leukemia, lung cancer, lymphoma, melanoma, prostate cancer and others. The FDA has approved targeted therapies for more than 15 types of cancer, including those of the breast, prostate, colon, and lung. Some of the products used for Breast cancer are Everolimus (Afinitor), tamoxifen (Nolvadex), toremifene (Fareston), Trastuzumab (Herceptin), fulvestrant (Faslodex), anastrozole (Arimidex), exemestane (Aromasin), lapatinib (Tykerb), letrozole (Femara), pertuzumab (Perjeta), ado-trastuzumab emtansine (Kadcyla), palbociclib (Ibrance), ribociclib (Kisqali), neratinib maleate (Nerlynx), abemaciclib (Verzenio), olaparib (Lynparza) etc.

TARGETED CANCER THERAPIES MARKET BY END USER

By various end users, the global targeted cancer therapies market is segmented into hospitals, cancer & radiation therapy centers and clinics. Overall, patients prefer less invasive outpatient procedures that can be performed in doctor’s office, instead of hospital procedures that would potentially require anaesthesia.

TARGETED CANCER THERAPIES MARKET BY GEOGRAPHY

By geography, the global targeted cancer therapies market is studied across the countries of key regions such as, North America, Europe, Asia Pacific and rest of the world regions which includes Latin America, and Middle East & Africa. North America dominated the global targeted cancer therapies market in 2018. A combination of factors such as technology innovations, medical insurance coverage, aging population, and changing lifestyles are seen to affect market dynamics significantly. The industry has seen several recent changes including growing competition, rise in merger and acquisition activities, increased cancer health insurance coverage, and an increasing amount of foreign direct investment. Also, Asia-Pacific is anticipated to be the fastest growing region during the forecast period. This market is hugely driven by rising demand and investment level of government. In more developed region such as Japan and China, the offerings from the market players are expected to be diverse, focused mainly on customized demands. Additionally, the market is predicted to witness expansion in terms of the newer forms of drugs because of rising cancer incidence and growing awareness.

TARGETED CANCER THERAPIES MARKET KEY PLAYERS

The leading market players of the global targeted cancer therapies market are Abbott Laboratories, AstraZeneca PLC, AVEO Pharmaceuticals Inc., Bayer AG, Boehringer Ingelheim GmbH, CYTOKINETICS INC., GlaxoSmithKline plc, OncoGenex Pharmaceuticals Inc., Sanofi and Pfizer, Inc. In June 2018, Bayer AG and the University of Texas MD Anderson Cancer Center signed a five-year collaboration agreement to accelerate the development of novel targeted treatments based on patient or tumor characteristics for which current therapies have not shown satisfactory clinical efficacy. Moreover, in July 2018, Sanofi and REVOLUTION Medicines, Inc. announced an exclusive partnership to develop and commercialize targeted therapies, based on the biology of the cellular enzyme SHP2, for patients with non-small lung cancer and other types of cancer carrying certain mutations.

Buy now Targeted Cancer Therapies Market Report https://www.axiommrc.com/buy_now/hc2030-targeted-cancer-therapies-market-report

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[davidjones3991-blog]

Global Non-Hodgkin’s Lymphoma and Chronic Lymphoma Treatment Market 2018-2025 - Industry Applications, Market Share, Segmentation, Company Share

Non-Hodgkin’s Lymphoma (NHL), has been expected to reach a new landscape in the forecast period due to the constant innovation and improvements on finding a viable drug to battle this disease. Due to the inability of major pharmaceuticals companies having a viable solution to it, the cost of treatment is very high and hence, the market is expected to soar higher in the forecast period of 2018-2025.

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Definition: Global Non-Hodgkin’s Lymphoma and Chronic Lymphoma Treatment Market

Non-Hodgkin’s Lymphoma is a type of cancer that attacks the lymphoma tic cells that are present in our immune system and fights off infection and diseases. It is commonly found in both adults and children, and these type of cancerous cells can be found anywhere throughout the body, as the lymphoma tic cells are spread throughout the body.

Market Drivers

·Increasing cases of cancer, and chronic diseases are also one of the major drivers of this market

·Improved healthcare services available in the major regions of the world would also be one of the major drivers

Market Restraints

·Rising cost treatment and drugs still yet to be approved by the specific authorities would prove to be a major road-block in its progress

·Chemotherapy’s side effects are also set to halt any major growth in the sector  

Market Segmentation: Global Non-Hodgkin’s Lymphoma and Chronic Lymphoma Treatment Market

·By treatment, all of the segments related to various treatments available in the market are set to witness worldwide growth due to the increasing cancer cases and no particular viable proven drug in the market. Global lymphoma treatment is set to witness healthy growth in all treatment segments.

·By geography, North America has been dominating the Non-Hodgkin’s Lymphoma treatment market due to its frequency of cancer cases, and it is set to continue that trend for the foreseeable future, followed by the APAC region of the world where it has developed better healthcare services and infrastructure.

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Key Developments in the Market:

·In August 2017,Gilead Sciences, Inc. and Kite Pharma, Inc. entered into a definitive agreement in August,2017 where the drug developed by Kite Pharma, Inc. currently under review by the US FDA, and is set to be one of the first drugs to be marketed for Non-Hodgkin’s Lymphoma

·In November 2017,US FDA approved a drug called Calquence by AstraZeneca, plc and will hit the market for an aggressive form of Non-Hodgkin’s Lymphoma in adults

Competitive Analysis: Global Non-Hodgkin’s Lymphoma and Chronic Lymphoma Treatment Market

Extensive R&D currently being conducted throughout the major pharmaceutical firms finding a treatment for Non-Hodgkin’s Lymphoma, but due to the high amount of R&D cost, it is proving to be a major hurdle in trying to find a viable solution and treatment.

More information for Report @ https://databridgemarketresearch.com/reports/global-non-hodgkins-lymphoma-and-chronic-lymphoma-treatment-market/  

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[rootsanalysis-blog]

The CAR-T therapies market is characterized by a healthy pipeline of promising therapies, and is projected to be worth around USD 14 Billion in 2030

Given the success of approved CAR-T cell therapies, such as KYMRIAH®, YESCARTA®, TECARTUS® and BREYANZI®, this upcoming class of biologics are anticipated to carve out a significant share of the multi-billion dollar cancer immunotherapy market

 Roots Analysis has announced the addition of “CAR-T Cell Therapy Market (3rd Edition) by Target Indications (NHL, Multiple Myeloma, Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Follicular Lymphoma, Mantle Cell Lymphoma, Hepatocellular Carcinoma and Others), Target Antigens (CD19, BCMA, CD19 / CD22, GPC3 and EGFR), Key Players and Key Geographies (North America, Europe, Asia Pacific, Latin America, Middle East and North Africa, and Rest of the World) – Industry Trends and Global Forecasts, 2021-2030” report to its list of offerings.

 Given their ability to selectively direct a cell mediated immune response against cancer cells and, thereby, offer prolonged periods of disease remission, several CAR-T cell therapies provide a promising therapeutic strategy for advanced stage cancers and are expected to achieve blockbuster status. With four approved products and many candidate therapies under evaluation for the treatment of multiple disease indications, the CAR-T cell therapy market is characterized by a healthy and growing pipeline. Further, with lucrative financial support and notable increase in partnerships, the CAR-T-cell therapies market is abuzz with activity.

 To order this 795+ page report, which features 165+ figures and 270+ tables, please visit https://www.rootsanalysis.com/reports/view_document/car-t-therapies-market/269.html

 Key Market Insights

 Over 755 CAR-T cell therapies are currently approved / under development

Close to 40% of the aforementioned candidates are in preclinical and discovery stages, while more than 25% are being evaluated in clinical stages (phase I/II and above). Examples of late-stage clinical candidates include bb2121, CD123/CLL1 CAR-T CD19 CAR-T and LCAR-B38M CAR-T / JNJ-68284528.

 Currently, the focus is on developing product candidates to treat various types of cancers

Over 95% of the products in the development pipeline are being evaluated for the treatment of hematological malignancies, including (in decreasing order of number of pipeline products) acute lymphoblastic leukemia, non-Hodgkin's lymphoma, multiple myeloma, and acute myeloid leukemia. Only 2% of current pipeline candidates are being developed for the treatment of non-oncological indications.

 Extensive efforts are underway to improve CAR constructs

Majority of the product candidates in the clinical pipeline, including the four approved drug products, are based on second generation CARs. Further, a number of novel therapies armed with fourth generation CAR constructs, CAR-based products containing humanized scFv and bispecific CARs (CD19+CD20 or CD19+CD22 or CD19+CD30) are being evaluated worldwide.

 China is leading the product development efforts related to CAR-T cell therapies, in terms of number of active trials and supporting hospitals

In the last 10 years, over half of the 410 clinical trials evaluating various types of CAR-T cell therapies, were registered in China. In addition, owning to a favorable clinical research environment, China is presently considered to be among the leading regions in the CAR-T cell therapy space, with close to 40 industry players and more than 100 non-industry players, including hospitals and universities, contributing to this field.

 Partnership activity within this domain has grown at a CAGR of 26%, between 2011 and 2020

More than 220 agreements were inked related to CAR-T cell therapies, with the maximum activity being reported in 2018. Majority of partnership deals signed within this domain were R&D agreements (21%), technology licensing (20%) and product development and commercialization agreements (11%).

Over USD 13 billion has been invested by both private and public investors, across more than 205 instances

It is important to mention that, between 2013 and 2020, majority of the funding was acquired through venture capital rounds (37%), other equity financing elements (24%), grants (12%) and secondary offerings (12%).

 The market is anticipated to grow at a CAGR of over 28%, during the period 2021-2030

Growth in this domain is anticipated to be primarily driven by encouraging clinical trial results and the recent success of the four approved CAR-T cell therapies. North America (primarily the US) and Europe are expected to capture over 75% of the market share by 2030, in terms of the sales-based revenues.

 To request a sample copy / brochure of this report, please visit https://www.rootsanalysis.com/reports/269/request-sample.html  

 Key Questions Answered

§  Who are the leading industry and non-industry players in this market?

§  What are the prevalent R&D trends in CAR-T cell therapies domain?

§  What are the key therapeutic areas for which CAR-T cell therapies are being / have been developed?

§  What are the challenges faced by stakeholders in this industry?

§  Which are the key geographies where extensive research on CAR-T cell therapies is being conducted?

§  Who are the key investors in this domain?

§  Who are the key opinion leaders / experts that can help in driving product development efforts in this field?

§  What kind of partnership models are commonly adopted by industry stakeholders?

§  What kind of contract manufacturing support is available for CAR-T cell therapies?

§  What kind of promotional strategies are likely to be adopted for CAR-T cell therapies that are approved / commercialized in future?

§  What are the factors that are likely to influence the evolution of this upcoming market?

§  How is the current and future market opportunity likely to be distributed across key market segments?

  The USD 14 billion (by 2030) financial opportunity within the CAR-T cell therapy market has been analyzed across the following segments:

 §  Disease indication

§  Non-Hodgkin lymphoma

§  Multiple myeloma

§  Chronic lymphocytic leukemia

§  Acute lymphoblastic leukemia

§  Follicular lymphoma

§  Mantle cell lymphoma

§  Hepatocellular carcinoma

§  Colorectal cancer

 §  Target antigens

§  CD19

§  BCMA

§  CD19, CD22

§  GPC3

§  EGFR

 §  Key Geographical Regions 

North America

Europe

Asia Pacific

Latin America

Middle East and     North Africa

Rest of the     World 

 The report features inputs from eminent industry stakeholders, according to whom CAR-T cell therapies are soon likely to witness increased adoption given their broad scope of applications in various advanced stage oncological disorders. The report includes detailed transcripts of discussions held with the following experts:

§  Tim Oldham (Chief Executive Officer, Cell Therapies)

§  Troels Jordansen (Chief Executive Officer, Glycostem Therapeutics)

§  Wei (William) Cao (Co-Founder, Chairman and Chief Executive Officer, Gracell Biotechnologies)

§  Miguel Forte (Chief Operating Officer, TxCell)

§  Adrian Bot (Vice President, Scientific Affairs, Kite Pharma)

§  Vincent Brichard (Vice President, Immuno-Oncology, Celyad)

§  Brian Dattilo (Manager of Business Development, Waisman Biomanufacturing)

§  Aino Kalervo (Competitive Intelligence Manager, Strategy & Business Development, Theravectys)

§  Xian-Bao Zhan (Professor of Medicine and Director, Department of Oncology, Changhai Hospital)

§  Enkhtsetseg Purev (Assistant Professor of Medicine, University of Colorado)

 The research includes brief profiles, featuring an overview of the company, its financial information (if available), and a description of its product(s), highlighting type of therapy and current development status. Each company profile includes technology portfolio (if available), recent developments related to T-cell immunotherapies and manufacturing capabilities of the companies. 

§  Autolus

§  bluebird bio

§  CARsgen Therapeutics

§  Celgene (A Bristol Myers Squibb Company)

§  Cellectis

§  Cellular Biomedicine Group

§  Innovative Cellular Therapeutics

§  Iovance Biotherapeutics

§  Kite Pharma (A Gilead Sciences Company)

§  Kuur Therapeutics

§  Noile-Immune Biotech

§  Novartis

§  Shanghai Genechem

§  Sinobioway Cell Therapy

§  Takara Bio

§  Ziopharm Oncology

 For additional details, please visit 

https://www.rootsanalysis.com/reports/view_document/car-t-therapies-market/269.html or email sales@rootsanalysis.com

 You may also be interested in the following titles:

1.     Global T-Cell Therapies Market (5th Edition), 2021 – 2030

2.     mRNA Therapeutics and Vaccines Market, 2020-2030

3.     Gene Therapies Market (4th Edition): Industry Trends and Global Forecasts, 2020-2030

4.     Oncolytic Virus Therapy Market: Pipeline Review, Developer Landscape and Competitive Insights, 2020-2030

  About Roots Analysis

Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com

  Contact:

Ben Johnson

+1 (415) 800 3415

+44 (122) 391 1091

Ben.johnson@rootsanalysis.com

[wemresearch]

Biosimilars Market Demand, Size, Share, Scope & Forecast to 2030

The Global Biosimilar Market is expected to be valued at USD 159.02 Billion by 2030 from USD 15.6 Billion in 2021, at a CAGR of 23.5% during the forecast period of 2021 to 2030.

Medicines known as biologics or biological products are created using living organisms through extremely intricate production procedures. They must be handled and administered under strict supervision. The term "biologics" refers to a broad range of goods, including vaccines, therapeutic proteins, monoclonal antibodies, and cell and gene therapies. Biologics are used to prevent, treat, or cure a number of illnesses, such as cancer, diabetes, cystic fibrosis, chronic kidney disease, and autoimmune disorders. Biologics are at the cutting edge of scientific and biological research and may be able to treat a variety of illnesses for which there are no other effective treatments.

A biotherapeutic product that is extremely similar to a reference biologic medication is referred to as a biosimilar, also known as a follow-on biologic. It has a complicated molecular structure and is made from living things or cells. Manufacturers rely on regulatory authority authorisation to launch the production of biosimilars when the patent on a biologic medication expires. A biological medication must be demonstrated to be identical in terms of quality, safety, and efficacy in order to be labelled as a biosimilar. Biosimilars are more expensive than generic medications because their production needs greater investment in R&D and is more complicated.

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Global Biosimilar Market: Segment Analysis

Biosimilar Market segment based on Molecule

• Filgrastim

• Rituximab

Filgrastim injection is for the treatment of Neutropenia, that is low white blood cells in the body, which is caused by cancer medicines. It is a synthetic form of substance that is produced naturally in your body known as colony stimulating factor. Filgrastim helps the bone marrow in the body to make new white blood cells itself.

Rituximab is used to treat certain types of Cancer such as Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Lukemia. It slows or stops the growth of cancer cells. Some products of Rituximab are also used to treat the pain of Rheumatoid Arthritis and can also decrease swelling and pain of the joints.

Segmentation based on Indication Insights

Oncology

Female Infertility

Oncology is the largest segment in this market due to the availability of Biosimilar at a lower price than Innovation Biologics and a large number of cancer patients. The availability of Biosimilar in Oncology has reduced the prices and made cancer treatment more accessible and affordable. Due to the high prevalence of cancer, healthcare systems across the globe are more concentrated on reducing the burden of cancer by adopting cost effective treatment options.

Biologics are too expensive and cannot be afforded by everyone. Therefore, cost-effective and new Biosimilars are being manufactured in the market. In January 2016, Teva Pharmaceutical Industries Ltd. introduced Ovaleap, a biosimilar to GONAL-f (follitropin alfa) from Merck KGaA. The low cost of Biosimilars promotes patient trust and boosts the market growth.

Segmentation based on Manufacturing

Contract Manufacturing

In- house Manufacturing

Based on the type of manufacturing, the market is classified into in-house manufacturing and contract manufacturing. Amongst these, in-house manufacturing holds the majority of the market share.

Top Key Players:-

LG Life Sciences

Fresenius SE & Co. KGaA

Pfizer, Inc.

Hospira

STADA Arzneimittel AG

Dr. Reddy’s Laboratories Ltd.

Eli Lilly and Company

Genentech (Roche Group).

Synthon Pharmaceuticals, Inc.

Celltrion

Boehringer Ingelheim

Amgen, Inc.

Gedeon Richter PLC

Merck Serono (Merck Group)

Teva Pharmaceutical Industries Ltd.

Biocon Limited

Samsung Biologics

Biogen idec, Inc.

Coherus BioSciences

Viatris, Inc

Fujifilm Kyowa Kirin Biologics Co., Ltd.

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Frequently Asked Questions (FAQ):

What is the impact of COVID-19 on the biosimilars market?

Who are the key players in the biosimilars market?

Which product segment dominates in the biosimilars market?

Which indication segment of the global biosimilars market is expected to witness the highest growth?

What is the market size for biosimilars market?

About We Market Research

WE MARKET RESEARCH is an established market analytics and research firm with a domain experience sprawling across different industries. We have been working on multi-county market studies right from our inception. Over the time, from our existence, we have gained laurels for our deep rooted market studies and insightful analysis of different markets.

Our strategic market analysis and capability to comprehend deep cultural, conceptual and social aspects of various tangled markets has helped us make a mark for ourselves in the industry. WE MARKET RESEARCH is a frontrunner in helping numerous companies; both regional and international to successfully achieve their business goals based on our in-depth market analysis. Moreover, we are also capable of devising market strategies that ensure guaranteed customer bases for our clients.

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[zaras2424]

Natural Killer Cells Therapeutics Market Analysis and Forecasts Research Report 2021-2030

Natural killer (NK) cells, also known as large granular lymphocytes (LGL), are defined as a type of cytotoxic lymphocyte which is critical to the innate immune system in the human body. NK cells belong to the innate lymphoid cells (ILC) which is a rapidly expanding family in the world of biological cells. They represent 5% to 20% of all circulating lymphocytes in humans. They are useful in the treatment of various types of cancers. Hence, many scientists are conducting research to explore new possible uses of NK cells regarding medical treatment. Increase in medical research in the field of natural killer cells therapeutics is profusely driving the growth of global natural killer cells therapeutics market. In recent years, scientists have started to re-engineer T cells to attack evasive tumors and creating the first Chimeric antigen receptor (CAR)-T treatments. Many researchers have also started to seriously explore how to do the same with natural killers. Experiments have been carried out by attaching CARs for CD19 to natural killer cells. With the cells being injected into patients with either non-Hodgkin lymphoma or chronic lymphocytic leukemia, so far majority cases have been turned out to be positive as the tumors of majority patients vanished.

Access the Full Report @ https://www.absolutemarketsinsights.com/reports/Natural-Killer-Cells-Therapeutics-Market-2021---2029-862

Investments towards enhancing effectiveness of natural killer cells therapeutics showcases positive growth opportunities for the global natural killer cells therapeutics market over the forecast period. CAR T is a new cell-based cancer immunotherapy. To provide a therapeutic anti­cancer effect, NK cells do not need any kind of antigen-specific priming. The efficacy of CAR modified peripheral blood natural killer cells being used for adoptive cell therapy of B-cell precursor acute lymphoblastic leukemia has been proven. Due to the spread of the China-originated coronavirus disease 2019 (COVID-19) which is also known as SARS-CoV-2 (SARS stands for Severe Acute Respiratory Syndrome), the immunological characteristics of COVID-19 are being researched. In some countries, NK cells are being experimented with the methods of lymphopenia to minimize the damage that coronavirus can cause to patients. A research to find a method using natural killer cells therapeutics for COVID treatment can be a big opportunity for the global natural killer cells therapeutics market.

Key Findings of the Report:

The global natural killer cells therapeutics market is anticipated to reach US$ 6317.20 Mn by 2029 growing at a CAGR of 17% during the forecast period (2021-2029).

The NK cell therapies category in the global natural killer cells therapeutics market held the larger market share in 2020. NK cells are capable of recognizing a wide range of ligands. Each of these can induce a cytolytic response. NK cells can also be easily isolated and expanded ex vivo. This allows for their use in adoptive or autologous cell therapies.

Cancer emerged as a dominant category under therapeutic indication in the global natural killer cells therapeutics market. The potent innate immune system effectors for cancer treatment can be harnessed from natural killer cells therapeutics. For example, in anticancer therapy, the checkpoint immunotherapy targets inhibitory receptors of T cells and reverses their functional blocking.

The peripheral blood segment held the largest share in the global natural killer cells therapeutics market in 2020. A medical technique called leukapheresis has made it possible to harvest cells directly from the peripheral blood of a donor. In this technique, immune cells are separated out from red blood cells. Peripheral blood mononuclear cells (PBMCs) are the most common source of NK cells. It is possible to collect PBMCs through apheresis or a specific gravity centrifugal method such as Ficoll separation.

Considering the end users segment, the hospitals & clinics segment occupied the largest market share in 2020 and is also anticipated to witness highest CAGR during the forecast period.

In 2020, North America was the biggest regional market in the global natural killer cells therapeutics market due to advanced medical research that was carried out in the medical institutions located in USA and Canada. Developed medical sector, presence of key market players, and technological advancement supporting the medical research, are some of the prominent factors contributing to the market growth in this region.

Some of the major players operating in the global natural killer cells therapeutics market are Acepodia Inc., Affimed GmbH, Artiva Biotherapeutics Inc., Bellicum Phamaceuticals Inc., Cytovia Therapeutics, Dragonfly Therapeutics, EMERCell, Fate Therapeutics, Fortress Biotech Inc., Glycostem, ImmunityBio Inc., Innate Pharma S.A., Kiadis Pharma, Nkarta Inc., NKGen Biotech, NKMAX Co. Ltd., and ONK Therapeutics Limited amongst others.

Global Natural Killer Cells Therapeutics Market:

By Type

NK Cell Therapies

Antibody Directed NK Cell Therapies

By Therapeutic Indication

Cancer

Viral Infections

Autoimmune Diseases

Neurodegenerative Diseases

Others

By Source

Peripheral Blood

Umbilical Cord Blood

Induced Pluripotent Natural killer cells therapeutics (iPSC)

Others

By End Users

Hospitals & Clinics

Research Institutes

Others

By Region:

North AmericaS. Canada Mexico Rest of North America

EuropeFrance The UK Spain Germany Italy Nordic CountriesDenmark Finland Iceland Sweden Norway Benelux UnionBelgium The Netherlands Luxembourg Rest of Europe

Asia PacificChina Japan India New Zealand Australia South Korea Southeast AsiaIndonesia Thailand Malaysia Singapore Rest of Southeast Asia Rest of Asia Pacific

Middle East & AfricaSaudi Arabia UAE Egypt Kuwait South Africa Rest of Middle East & Africa

Latin AmericaBrazil Argentina Rest of Latin America

Contact Us:

Company: Absolute Markets Insights Email id: sales@absolutemarketsinsights.com Phone: +91-740-024-2424 Contact Name: Shreyas Tanna Website: https://www.absolutemarketsinsights.com

[delveinsight12]

Central Nervous System Lymphoma Market to Witness Growth by 2032 | Companies- Novartis, Prelude Therapeutics, Kite, Celgene

DelveInsight's "Central Nervous System Lymphoma Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of Central Nervous System Lymphoma, historical and forecasted epidemiology as well as the Central Nervous System Lymphoma market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The Central Nervous System Lymphoma market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Central Nervous System Lymphoma market size from 2019 to 2032, segmented by seven major markets. The Report also covers current Central Nervous System Lymphoma treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Central Nervous System Lymphoma market.

Central Nervous System Lymphoma Overview

Central nervous system lymphoma is a rare non-Hodgkin lymphoma in which malignant (cancer) cells from lymph tissue form in the brain and/or spinal cord (primary CNS) or spread from other parts of the body to the brain and/or spinal cord (secondary CNS). Central nervous system lymphoma is more common in men than women. the exact causes of CNS lymphoma are not known, there are several factors that may increase a person's risk for developing the disease, such as having a compromised immune system due to acquired immunodeficiency syndrome (AIDS), other disorders of the immune system, or chronic immunosuppression (a reduced function of the immune system) as a result of organ transplantation. To diagnose Central Nervous System lymphoma different tests are used to examine the eyes, brain and spinal cord. Physical exam and history, neurological exam to check mental status, coordination, ability to walk normally and how well the muscles, senses and reflexes work, slit-lamp eye exam - this test uses a special microscope with a bright, narrow slit of light to check the outside and inside of the eye. Vitrectomy - A surgical procedure in which some of the vitreous humor (the gel-like fluid inside the eyeball) is removed and examined under a microscope to check for cancer cells. Chest x-ray and CT scans of the chest and abdomen. MRI scans of the brain and spinal cord. There is no standard treatment for Central Nervous System lymphoma. Methotrexate-based combinations that include rituximab (Rituxan) have been the most successful for Central Nervous System lymphoma patients. Methotrexate is usually given at high doses and requires that the patient be hospitalized while giving the chemotherapy.

Learn more about Central Nervous System Lymphoma, treatment algorithms in different geographies, and patient journeys. Contact to receive a sample @ Central Nervous System Lymphoma Market Outlook 2032

Central Nervous System Lymphoma Market 

The Central Nervous System Lymphoma market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Central Nervous System Lymphoma market trends by analyzing the impact of current Central Nervous System Lymphoma therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.

This segment gives a thorough detail of the Central Nervous System Lymphoma market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Central Nervous System Lymphoma market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to DelveInsight, the Central Nervous System Lymphoma market in 7MM is expected to witness a major change in the study period 2019-2032.

Request a sample and discover more about the report offerings at: https://www.delveinsight.com/sample-request/central-nervous-system-lymphoma-market

Central Nervous System Lymphoma Epidemiology 

The Central Nervous System Lymphoma epidemiology section provides insights into the historical and current Central Nervous System Lymphoma patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Central Nervous System Lymphoma market report also provides the diagnosed patient pool, trends, and assumptions. 

Click here and explore more about Central Nervous System Lymphoma Epidemiology

Central Nervous System Lymphoma Drugs Uptake

This section focuses on the uptake rate of the potential Central Nervous System Lymphoma drugs recently launched in the Central Nervous System Lymphoma market or expected to be launched in 2019-2032. The analysis covers the Central Nervous System Lymphoma market uptake by drugs, patient uptake by therapies, and sales of each drug.   

Central Nervous System Lymphoma Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Central Nervous System Lymphoma market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Key Central Nervous System Lymphoma Companies

• Shandong New Time Pharmaceutical

• PIQUR Therapeutics

• Ono Pharmaceutical

• Janssen, LP

• Kazia Therapeutics

• Beijing InnoCare Pharma Tech

• Celltrion

• Bristol Myers Squibb

• AstraZeneca

• Novartis

• Prelude Therapeutics

• Kite, A Gilead Company

• Celgene

Central Nervous System Lymphoma Pipeline Development Activities

The Central Nervous System Lymphoma report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Central Nervous System Lymphoma key players involved in developing targeted therapeutics.

Request for a sample report to understand more about the Central Nervous System Lymphoma pipeline development activities at: Central Nervous System Lymphoma Therapy Assessment

Central Nervous System Lymphoma Therapeutics Assessment

Major key companies are working proactively in the Central Nervous System Lymphoma Therapeutics market to develop novel therapies which will drive the Central Nervous System Lymphoma treatment markets in the upcoming years.

Get the Detailed TOC of the Central Nervous System Lymphoma Market report here: Central Nervous System Lymphoma Market

[ken-research-market-research]

Global Bendamustine Injection Market 2021 Industry Analysis by Sales, Demand, Upcoming Trends, Consumption and Growth, Forecast 2027: Ken Research

Global Bendamustine Injection Market 2021 Industry Analysis by Sales, Demand, Upcoming Trends, Consumption and Growth, Forecast 2027: Ken Research

Bendamustine injection is utilized to cure chronic lymphocytic leukemia (CLL; a type of cancer of the white blood cells). Bendamustine injection is also utilized to treat a type of non-Hodgkins lymphoma (NHL: cancer that starts in a type of white blood cell that generally fights infection) that is sluggish spreading, but has persisted to worsen throughout or after treatment with another…

[healthcare-market]

BCL-2 (B-cell lymphoma 2) Inhibitors Market Trends and Forecast up to 2027

BCL-2 (B-cell lymphoma 2) Inhibitors Market: Introduction

· BCL-2, also known as B Cell Lymphoma 2, is a protein encoding gene belonging to the B cell lymphoma family. This protein is considered to be an outer mitochondrial protein membrane, which functions as a signaling pathway to further control the mitochondrial permeability against the apoptotic stimuli response. Aberrant expression and translocation of chromosomes are considered to be cancer symptoms in various tissues. The BCL-2 family comprise the 25-apoptotic and anti-apoptotic members that maintain a balance between new forming cells and old dying cells.

· Venetoclax is the only and fist approved FDA BCL-2 inhibitor drug for chronic lymphocytic lymphoma (CLL) patients. Although various clinical trials are being carried out for the development of new BCL-2 inhibitors.

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Key Drivers and Restraints of Global BCL-2 (B-cell lymphoma 2) Inhibitors Market

· There is a rise in the prevalence of Diffuse B cell Lymphoma (DLBCL), a common type of non-Hodgkin lymphoma. As per Lymphoma Research Foundation article, in 2019, in the U.S., DLBCL accounted for 22% of new diagnosed B cell lymphoma cases. Each year, 18,000 people are diagnosed with DLBCL globally. This B cell lymphoma affects people over 60 years of age. As per the American Cancer Society's, in the year 2019, 20,720 people are estimated to be diagnosed with CLL. Moreover, 90% of the people diagnosed with CLL are estimated to affecting people above 50 years of age. In the U.S., 2,220 men and 1,710 women are expected to be suffering from CLL every year. Moreover, as per the American Cancer Society, about 3,930 death are expected to take place in 2019.

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· Governments of developed and developing countries are initiating awareness campaigns to reduce mortality and morbidity rates. This is expected to boost the demand in the effective cancer treatment. For instance, Public Health England, an executive agency of the Department of Health in the U.K., started “Be Clear on Cancer” campaign aimed at improving early diagnosis of cancer by holding the public awareness program. In April 2016, the U.S. Government allocated US$ 5.2 Bn for the National Cancer Institute (NCI), a Federal Government agency, for cancer research and training. The budget increased by 5.3% as compared to the previous year. NCI conducts clinical trials on cancer patients who require repetitive diagnosis to check the prognosis of cancer.

· Availability of BCl-2 inhibitors is limited, the first and only approved drug for the BCL 2 inhibitor is Venetoclax. The FDA approved this drug as a second line treatment for CLL. This limits the availability of treatment to physicians and patients globally.

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Combination Therapy a Preferred Treatment for CLL

· Venetoclax is the only selective inhibitor of the BCL-2 for the relapsed /refractory CLL with 17p deletion depending on the high response rate and safety profile. The inhibitor belongs to the BH3-mimetics class, which is an emerging and novel compound class for the treatment of the BCL-2 indication.

· Various clinical settings have proved the combination of Venetoclax with other compounds successful in treating the BCL-2 indication. Venetoclax is expected to be used in combination with other agents. As compared to monotherapy, the usage of Venetoclax in combination with other drugs reduces adverse events in patients of nausea, diarrhea, thrombocytopenia, and others.

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North America to Lead Global BCL-2 (B-cell lymphoma 2) Inhibitors Market

· In terms of region, the global BCL-2 (B-cell lymphoma 2) inhibitors market can be divided into: North America, Europe, Asia Pacific, Latin America, and Middle East & Africa

· North America is expected to lead the global BCL-2 Inhibitors market, owing to rising cases of CLL and hematology malignancies patient pool. Moreover, approval for Venetoclax in the region, along with combination with other drugs is likely to the drive the market in the region. Ongoing strategic collaborations are also anticipated to fuel the development of the North America BCL-2 inhibitors market. Technological advancement and investments in research & development will propel the market in the region.

· Campaigns for creating awareness about CLL and treatments are likely to boost the demand for BCL-2 inhibitors

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[udaycmi]

Blood Cancer Drugs Market to Generate Exciting Opportunities in the Industry by 2027

The global blood cancer drugs market is anticipated to reach USD 55.6 billion by 2025 according to a new report published by Polaris Market Research. The report ‘Blood Cancer Drugs Market [By Blood Cancer Type (Leukemia (Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia), Lymphoma (Hodgkin Lymphoma, Non-Hodgkin Lymphoma (B-Cell Lymphoma, T-Cell Lymphoma)), and Myeloma; By Drugs (Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others); By Treatment Approaches (Chemotherapeutic, mAbs/Targeted Therapies, and Immunotherapeutic); By Region]: Market Size & Forecast, 2017 – 2025’ provides insights on the current market scenario and the future prospects.

The demand for blood cancer drug is primarily driven by growing death incidences by blood cancer, and continuous innovation for developing novel treatments with the help of several ongoing clinical trials. Moreover, increasing research and development of biological and targeted therapies as treatment will spur the blood cancer drugs market during the upcoming period. However, the high price of drugs and the stringent government policies will limit the growth of blood cancer drugs market during the forecast period.

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Most of the blood cancers start in the bone marrow, where blood is produced. In blood cancer the growth of normal blood cells is dislodged by the uncontrollable growth of abnormal blood cells. These cancerous cells prevent the blood from performing many of its functions. Hence, the existing treatments of blood cancer are being the foundation for developing the new drugs. The steady flow of the blood cancer drugs has created opportunity for research and development in the existing market. For instance, Amgen Inc. received approval for BLINCYTO in July 2017, which is used in treating B-cell precursor Acute Lymphoblastic leukemia. Similarly, European blood cancer drugs market witnessed the approvals of Gazyvaro, by Roche AG that is used in treating advanced follicular lymphoma. Also, novel technologies like CAR-T are likely to be launched this year.

The global blood cancer drugs market is segmented into blood cancer type, drugs and treatment approaches. On the basis of blood cancer type, the global blood cancer drugs market is segmented into leukemia, lymphoma and myeloma. The lymphoma segment is expected to drive the majority market of blood cancer drugs followed by leukemia. The global market of this segment is primarily driven by the increasing prevalence of lymphoma, and presence of effective treatments in the market. On the basis of drugs, the global blood cancer drugs market is further categorized into Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others. This continuous innovation for treating various sub-types of blood cancers has led to the development of novel types of treatments. For instance, the combination of Revlimid and Velcade has emerged as the preferential drugs in trials for treating multiple myeloma.

The leading companies operating in this industry include Johnson & Johnson Inc., Amgen Inc., Bayer AG., Pfizer, Inc., AbbVie Inc., Roche Holding AG., Celgene Corporation, AstraZeneca, Novartis AG, GlaxoSmithKline PLC, Merck & Co., Inc., and Eli Lily & Co. among others.

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Polaris Market Research is a global market research and consulting company. The company specializes in providing exceptional market intelligence and in-depth business research services for our clientele spread across different enterprises. We at Polaris are obliged to serve our diverse customer base present across the industries of healthcare, technology, semi-conductors and chemicals among various other industries present around the world

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[techsciresearch]

Non-Hodgkin Lymphoma Therapeutics Market to Grow with 10.02% CAGR until 2026 – TechSci Research

Increasing prevalence of Non-Hodgkin lymphomas (NHL) and other types of cancers to drive global Non-Hodgkin Lymphoma (NHL) therapeutics market

According to TechSci Research report, “Global Non-Hodgkin Lymphoma (NHL) Therapeutics Market By Type of Therapy (Immunotherapy, Targeted Therapy, Chemotherapy, Stem Cell Transplant, Others), By Cell Type (B-cell Lymphomas, T-cell Lymphomas), By Drug Type (Revlimid, Rituxan, Keytruda, Imbruvica, Opdivo, Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies, Others), By Region, Competition Forecast & Opportunities, 2026”, the market was valued at USD7931.54 million in 2020 and is expected to reach USD14689.31 million in 2026 by witnessing double digit CAGR of 10.02% during the forecast period. The global Non-Hodgkin Lymphoma (NHL) therapeutics market is primarily driven by growing prevalence of Non-Hodgkin’s lymphomas (NHL) and other types of cancers around the world coupled with increasing expenditure on medical and healthcare infrastructure. Also, increasing awareness towards the effects of Non-Hodgkin’s lymphomas (NHL) and extensive R&D activities are acting as some other major drivers for this market. In addition to this, factors like the US Food and Drug Administration’s approval for chronic lymphocytic leukemia therapy drugs and increasing demand for innovative drugs and novel technologies are expected to drive the market growth through 2026.

Moreover, patent expiry of standard drugs, especially in untapped markets is anticipated to provide profitable growth opportunities for this market in near future. Apart from this, improved diagnostic techniques to detect NHL is fueling the growth of global Non-Hodgkin Lymphoma (NHL) therapeutics market. However, the market is also susceptible to some restraints. High cost of NHL drugs and stringent regulatory guidelines is anticipated to limit the market growth. Furthermore, various complications associated with NHL drugs are expected to hamper the global Non-Hodgkin Lymphoma (NHL) therapeutics market growth in coming years.

Browse 132 figures spread through 110 Pages and an in-depth TOC on "Global Non-Hodgkin Lymphoma Therapeutics Market"

https://www.techsciresearch.com/report/non-hodgkin-lymphoma-nhl-therapeutics-market/5113.html

The global Non-Hodgkin Lymphoma (NHL) therapeutics market is segmented based on type of therapy, cell type, drug type, distribution channel and region. Based on type of therapy, the market can be segmented into immunotherapy, targeted therapy, chemotherapy, stem cell transplant, others. Among these, immunotherapy segment dominated the market in 2020 and is further projected to maintain its dominance in the next 5 years as well. This can be attributed to higher revenue realization by these drugs. Targeted therapy is anticipated to register highest growth in the market over the coming years owing to high accuracy of these therapies in targeting cancer.  In addition to this, presence of large number of targeted therapies for Non-Hodgkin Lymphoma (NHL) treatment is another factor which is further contributing to the high growth of this segment.

Regionally, North America dominated global Non-Hodgkin Lymphoma therapeutics market in 2020. High prevalence of Non-Hodgkin lymphoma (NHL) in the region and efforts by leading pharmaceutical companies to develop efficient treatment options is further expected to aid the market growth in North America during the forecast period. The second most dominating market is expected to be Europe on account of growing number of patients requiring treatment in the region and high usage of advanced therapeutics. However, Asia-Pacific is anticipated to undergo fastest growth through 2026 due to improving healthcare reimbursement policies and increasing prevalence of Non-Hodgkin lymphoma (NHL) among the population in the region.

Major players operating in the global Non-Hodgkin Lymphoma (NHL) therapeutics market include AstraZeneca PLC, Baxter International Inc., Bayer AG, Novartis AG, Eli Lilly and Company, Spectrum Pharmaceuticals, Inc., Teva Pharmaceutical Industries Ltd., Bristol Myers Squibb Company, GlaxoSmithKline PLC, Janssen Pharmaceuticals, Inc., F. Hoffmann-La Roche Ltd, Sanofi S.A., Merck & Co., Inc., Kyowa Kirin Co., Ltd. and AbbVie Inc. The market is highly competitive and key market players are investing on R&D activities to introduce new and more effective products in global market.  

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“Extensive R&D activities are the most important tool for the growth of Non-Hodgkin Lymphoma  therapeutics market, which is why, large number of pharmaceutical companies are engaged in these activities to develop innovative formulations. Also, availability of the biosimilars at a reduced price is leading to high growth in global Non-Hodgkin Lymphoma (NHL) therapeutics market,” said Mr. Karan Chechi, Research Director with TechSci Research, a research based global management consulting firm.

“Global Non-Hodgkin Lymphoma (NHL) Therapeutics Market By Type of Therapy (Immunotherapy, Targeted Therapy, Chemotherapy, Stem Cell Transplant, Others), By Cell Type (B-cell Lymphomas, T-cell Lymphomas), By Drug Type (Revlimid, Rituxan, Keytruda, Imbruvica, Opdivo, Others), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies, Others), By Region, Competition Forecast & Opportunities, 2026” has evaluated the future growth potential of global Non-Hodgkin Lymphoma (NHL) therapeutics market and provides statistics & information on market size, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges and opportunities in global Non-Hodgkin Lymphoma (NHL) therapeutics market.

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