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oddwayintt · 8 months
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Get Relief from Atopic Dermatitis Symptoms with Crisaborole Ointment
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Atopic dermatitis, also known as eczema, is a common chronic skin condition characterized by red, itchy rashes. The inflammation and irritation associated with eczema can significantly impact quality of life. However, new treatment options like crisaborole topical ointment are providing hope.
What is Crisaborole?
Crisaborole is the active ingredient in a topical ointment used to treat mild to moderate atopic dermatitis. Crisaborole 2% ointment, sold under the brand name Eucrisa, contains 2% w/w crisaborole as the pharmacologically active component.
Crisaborole is a non-steroidal phosphodiesterase-4 (PDE-4) inhibitor. PDE-4 is an enzyme that breaks down cyclic adenosine monophosphate (cAMP) in immune cells. cAMP is a signaling molecule that regulates inflammatory responses. By inhibiting PDE-4, crisaborole increases cAMP levels, reducing inflammatory cytokine production and relieving atopic dermatitis symptoms.
How Does Crisaborole Ointment Work?
When applied topically, crisaborole ointment acts locally at the site of application to inhibit PDE-4 and reduce inflammation. The ointment quickly absorbs into the skin, getting to work on easing eczema flare-ups.
Within days of starting Crisnuo ointment, many patients experience decreased redness, itching, and skin lesions. The anti-inflammatory properties of crisaborole improve the visible signs and irritating symptoms of atopic dermatitis.
Continued use helps rein in inflammatory pathways, calm immune responses, and prevent future flare-ups. Crisnuo ointment works to control eczema day after day when applied as directed.
What Are the Benefits of Using Crisaborole?
Crisaborole offers certain advantages over other eczema treatments:
Steroid-free - Crisaborole manages inflammation without steroids' side effects.
Fast-acting - Crisaborole provides quick relief within days.
Safe for long-term use - Patients can use crisaborole daily for up to a year.
Well-tolerated - Most patients have no issues with burning or stinging.
Easy to use - Crisaborole comes in an easy-to-apply ointment.
Effective - Studies show crisaborole significantly improves eczema symptoms.
By controlling flare-ups and reducing the need for steroids, crisaborole can be an important medication for atopic dermatitis patients.
Who Should Use Crisaborole Ointment?
Crisaborole is FDA approved to treat mild to moderate eczema in adults and children as young as 2 years old. Patients with atopic dermatitis that is not well-controlled with other moisturizing topicals may benefit from adding crisaborole.
Crisaborole offers an effective steroid-free option for sensitive areas like the face and skin folds. It is also a good choice for chronic eczema patients who need safe long-term treatment.
Talk to your dermatologist to see if crisaborole makes sense for your or your child's eczema management plan.
How Should You Apply and Use Crisaborole?
Use crisaborole ointment exactly as instructed:
Apply a thin layer directly to affected areas.
Gently rub in until fully absorbed. Do not bandage or cover treated areas.
Avoid using on open wounds or damaged skin.
Continue using even after eczema improves to prevent flare-ups.
Stop use if irritation occurs and consult your doctor.
Crisaborole is for external use only. Follow your dermatologist's advice on incorporating crisaborole with other medications. Proper use offers the best results.
Are There Any Potential Side Effects?
Crisaborole is well tolerated by most patients. Mild application site reactions like stinging, burning, or redness can sometimes occur.
In clinical trials, the most common adverse events were vomiting, fever, diarrhea, headache, cough, nausea, nasopharyngitis, rhinovirus, bronchitis, otitis externa, pharyngitis, and ear infection. Such systemic side effects were determined to be unrelated to crisaborole use.
Talk to your doctor right away if any concerning reactions develop when using crisaborole topical ointment. Seek emergency care for severe allergic reactions like rash, itching, swelling, or trouble breathing.
Give Crisaborole a Try for Atopic Dermatitis Relief
Managing eczema flare-ups is extremely challenging. Topical steroids provide important relief but cannot be used long term.
Crisaborole offers an effective non-steroidal treatment option for mild to moderate atopic dermatitis. When applied properly, it can curb symptoms and improve quality of life. Talk to your dermatologist to see if crisaborole ointment should be part of your or your child's eczema management plan.
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